Prolactin receptor modulators
Prolactin Agonists Growth hormone Human placental lactogen Placental growth hormone (growth hormone variant) Prolactin S179D-hPRL Somatotropin An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks
Prolactin (PRL)
Prolactin (PRL), also known as lactotropin, is a protein best known for its role in enabling mammals to produce milk. It is influential in over 300 separate processes in various vertebrates, including humans. Bole-Feysot C, Goffin V, Edery M, Binart N, Kelly PA (June 1998). "Prolactin (PRL)
Gastrin-releasing peptide aka GRP and Pro-Gastrin-Releasing-Peptide aka Pro-GRP (and something called PreProGRP?)
Gastrin-releasing peptide, also known as GRP, is a neuropeptide, a regulatory molecule that has been implicated in a number of physiological and pathophysiological processes. Most notably, GRP stimulates the release of gastrin from the G cells of the stomach. The gene from which GRP is derived encodes a number
Progastrin
Progastrin is an 80-amino acid intracellular protein and the precursor of gastrin, a gastrointestinal hormone produced by G cells in the gastric antrum.Fiona M., Gribble; Frank, Reimann; Geoffrey, P. Roberts (2018). Gastrointestinal Hormones. Physiology of the Gastrointestinal Tract, Elsevier. pp. 31â70. The main function of gastrin is to regulate acid secretion.Rehfeld, Jens F.; Goetze,
Gastrin
Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas. Gastrin binds to cholecystokinin B receptors to stimulate the release of histamines in enterochromaffin-like cells, and it
Several high-ranking government officials closely tied to the approval and subsequent defense of aspartame took jobs in the NutraSweet industry
U.S. Attorney Samuel Skinner went to work for Sidley & Austin, G.D. Searle's law firm. Assistant U.S. Attorney William Conlon went to work for Sidley & Austin. H.R. Roberts, director of the FDA's Bureau of Food took a job as vice president
After an unsuccessful bid in the late ’70s, G.D. Searle reapplied for FDA approval of aspartame the day after Ronald Reagan was inaugurated.
G.D. Searle CEO Donald Rumsfeld served as a key member of Reagan's transition team. In April 1981 From Sweetheart Deal President Ronald Reagan introducing new Mideast Envoy Donald Rumsfeld, Nov 1, 1983 Thoughts for another day: Rumsfeld - 'Valiant Thor'? đ¤¨
Ezekiel Stone Wiggins (1839 â 1910) was a Canadian weather and earthquake predictor known as the “Ottawa Prophet”
He was also the author of several scientific, educational and religious works. Wiggins wrote the "Architecture of the Heavens containing a new theory of the universe and the extent of the deluge, and testimony of the Bible and geology in opposition
No proof for the need of zinc in human cells was shown until the late 1930s where its presence was demonstrated in carbonic anhydrase and the 1960s where it was identified as a necessary element for humans
Zinc was identified to be essential in fungal growth of yeast as shown by Jules Raulin in 1869 yet no proof for the need of zinc in human cells was shown until the late 1930s where its presence was demonstrated in carbonic anhydrase and the 1960s where
Rennet
Animal rennet to be used in the manufacture of cheddar cheese For the apple varieties, see Reinette Rennet is a complex set of enzymes produced in the stomachs of ruminant mammals. Chymosin, its key component, is a protease enzyme that curdles the casein in milk. In addition to chymosin, rennet contains other enzymes, such as pepsin and a lipase. Rennet has traditionally been
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Chymase and Chymosin – Rumored To Be Synonyms (and a little renin and rennin)
Chymase Alternative name for chymosin ["chymase ." A Dictionary of Food and Nutrition. . Encyclopedia.com. 25 Aug. 2022 https://www.encyclopedia.com] Mast Cell Chymase and Tryptase and some MMPs Chymase and tryptase are packaged in secretory granules together with histamine and other mediators in mast cells, which are infiltrated in rheumatoid synovium. Chymase is a chymotrypsin-like
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