In 1780, the former Holy Innocents’ Cemetery in Paris was closed because of overuse. In 1786, the bodies were exhumed and the bones were moved to the Catacombs.[ “Paris’ Les Innocents cemetery”. Retrieved February 6, 2011.] Many bodies had incompletely decomposed and had reduced into deposits of fat. During the exhumation, this fat was collected and subsequently turned into candlesContinue Reading

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pharmacy (n.) late 14c., farmacie, “a medicine that rids the body of an excess of humors (except blood);” also “treatment with medicine; theory of treatment with medicine,” from Old French farmacie “a purgative” (13c.) and directly from Medieval Latin pharmacia, from Greek pharmakeia “a healing or harmful medicine, a healing or poisonous herb; a drug, poisonous potion;Continue Reading

The Aztecs were particularly noted for practicing human sacrifice on a large scale; an offering to Huitzilopochtli would be made to restore the blood he lost, as the sun was engaged in a daily battle. Human sacrifices would prevent the end of the world that could happen on each cycle of 52 years. InContinue Reading

Plant matrix metalloproteinases are metalloproteins and zinc enzymes found in plants. Matrix Metalloproteinase Matrix metalloproteinases (MMPs) are zinc endopeptidases, commonly called metzincins. MMP enzymes represent an ancient family of proteins with major similarities in genetic make-up that are present in a range of diverse organisms from unicellular bacteria to multicellular vertebrates and invertebrates. The superfamily is distinguished due to itsContinue Reading

The MMPs belong to a larger family of proteases known as the metzincin superfamily.[ Matrix Metalloproteinases: Its implications in cardiovascular disorders] Collectively, these enzymes are capable of degrading all kinds of extracellular matrix proteins, but also can process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligandsContinue Reading

Carnoy’s solution is a fixative composed of 60% ethanol, 30% chloroform and 10% glacial acetic acid, 1 gram of ferric chloride.[1][2] Carnoy’s solution is also the name of a different fixation composed of ethanol and glacial acetic acid (3:1).[3][4][5] Hm..and here are some articles that come up on a search for Carnoy’s solution at Science Direct I haven’tContinue Reading

In biology, histones are highly basic proteins abundant in lysine and arginine residues that are found in eukaryotic cell nuclei. They act as spools around which DNA winds to create structural units called nucleosomes.[1][2] Nucleosomes in turn are wrapped into 30-nanometer fibers that form tightly packed chromatin. Histones prevent DNA from becoming tangled and protect it from DNA damage. In addition, histones play important roles in gene regulation and DNA replication. WithoutContinue Reading

Heterochromatin is a tightly packed form of DNA or condensed DNA, which comes in multiple varieties. These varieties lie on a continuum between the two extremes of constitutive heterochromatin and facultative heterochromatin. Both play a role in the expression of genes. Because it is tightly packed, it was thought to be inaccessible to polymerases and therefore not transcribed;Continue Reading

Lipofuscin is the name given to fine yellow-brown pigment granules composed of lipid-containing residues of lysosomal digestion.[1][2] It is considered to be one of the aging or “wear-and-tear” pigments, found in the liver, kidney, heart muscle, retina, adrenals, nerve cells, and ganglion cells.[3] Formation and turnover Lipofuscin appears to be the product of the oxidation of unsaturated fatty acids and may be symptomatic of membrane damage, or damage to mitochondria and lysosomes. AsideContinue Reading

Leydig cells, also known as interstitial cells of the testes and interstitial cells of Leydig, are found adjacent to the seminiferous tubules in the testicle and produce testosterone in the presence of luteinizing hormone (LH).[1][2] They are polyhedral in shape and have a large, prominent nucleus, an eosinophiliccytoplasm, and numerous lipid-filled vesicles.[3] Structure The mammalian Leydig cell is a polyhedral epithelioid cell with aContinue Reading

Nitrophenols are compounds of the formula HOC6H5−x(NO2)x. The conjugate bases are called nitrophenolates. Nitrophenols are more acidic than phenol itself. Wikipedia Mono-nitrophenols with the formula HOC6H4NO2. Three isomeric nitrophenols exist: o-Nitrophenol (2-nitrophenol; OH and NO2 groups are neighboring; CAS number: 88-75-5), a yellow crystalline solid (m.p. 46 °C). m-Nitrophenol (3-nitrophenol, CAS number: 554-84-7), a yellow solid (m.p. 97Continue Reading