Nepenthesin (and the carnivorous plants it comes from)

Nepenthesin (also spelled nepenthacin or nepenthasin) is an aspartic protease of plant origin that has so far been identified in the pitcher secretions of Nepenthes and in the leaves of Drosera peltata. Discovery In the late 19th century, Sydney Howard Vines showed that…

Cell surface receptor deficiencies

Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the plasma membrane of cells. They act in cell signaling by receiving (binding to) extracellular molecules. They are specialized integral membrane proteins that allow communication between the cell and…

Disorders of bleeding and clotting

Clotting By cause Clotting factors Antithrombin III deficiency Protein C deficiency Activated protein C resistance Protein S deficiency Factor V Leiden Prothrombin G20210A Platelets Sticky platelet syndrome Thrombocytosis Essential thrombocythemia DIC Purpura fulminans…

Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01)

Antiplatelet drugs Glycoprotein IIb/IIIa inhibitors Abciximab Eptifibatide Orbofiban Roxifiban Sibrafiban§Tirofiban ADP receptor/P2Y12 inhibitors Thienopyridines Clopidogrel Prasugrel Ticlopidine Nucleotide/nucleoside analogs Cangrelor Elinogrel Ticagrelor Prostaglandin analogue (PGI2) Beraprost Iloprost Prostacyclin Treprostinil COX inhibitors Acetylsalicylic acid/Aspirin# Aloxiprin Carbasalate…

Integrin αIIbÎČ3 – Glycoprotein IIb/IIIa

In medicine, glycoprotein IIb/IIIa (GPIIb/IIIa, also known as integrin αIIbÎČ3) is an integrin complex found on platelets. It is a receptor for fibrinogen[1] and von Willebrand factor and aids platelet activation. The complex is formed via calcium-dependent association of gpIIb and gpIIIa,…

List of human clusters of differentiation (OR CD) MOLECULES

* = group; ** = not listed on hcdm CD1* MHC-like molecule that presents lipid molecules CD1a CD1a (Cluster of Differentiation 1a), or T-cell surface glycoprotein CD1a, is a human protein encoded by the CD1A gene. An antigen-presenting…

Tetraspanin

Tetraspanins are a family of membrane proteins found in all multicellular eukaryotes. Tetraspanins, also referred to as the transmembrane 4 superfamily (TM4SF) proteins, have four transmembrane alpha-helices and two extracellular domains, one short (called the small extracellular domain or loop, SED/SEL…

Cell membrane protein disorders (other than Cell surface receptor, enzymes, and cytoskeleton)

Arrestin Oguchi disease 1 Myelin Pelizaeus–Merzbacher disease – Dejerine–Sottas disease – Charcot–Marie–Tooth disease 1B, 2J Pulmonary surfactant Surfactant metabolism dysfunction 1, 2 Cell adhesion molecule IgSF CAM:OFC7 – Cadherin: DSG…

X-Linked Disorders

X-linked dominant inheritance X-linked dominant X-linked hypophosphatemia – Focal dermal hypoplasia – Fragile X syndrome – Aicardi syndrome – Incontinentia pigmenti – Rett syndrome – CHILD syndrome – Lujan–Fryns syndrome…

Inborn error of purine–pyrimidine metabolism

Inborn errors of purine–pyrimidine metabolism are a class of inborn error of metabolism disorders specifically affecting purine metabolism and pyrimidine metabolism. An example is Lesch–Nyhan syndrome. Urine tests may be of use in identifying some of these…

Orotidine 5′-phosphate decarboxylase

Orotidine 5′-phosphate decarboxylase (OMP decarboxylase) or orotidylate decarboxylase is an enzyme involved in pyrimidine biosynthesis. It catalyzes the decarboxylation of orotidine monophosphate (OMP) to form uridine monophosphate (UMP). The function of this enzyme is essential to the de novo biosynthesis of the pyrimidine nucleotides uridine…

  • Zinc
  • January 3, 2023
IQGAP1

Ras GTPase-activating-like protein IQGAP1 (IQGAP1) also known as p195 is a ubiquitously expressed protein that in humans is encoded by the IQGAP1gene.[5][6][7] IQGAP1 is a scaffold protein involved in regulating various cellular processes ranging from organization of the actincytoskeleton, transcription,…