Paracetamol has been reported to be as effective as aspirin in the treatment of musculoskeletal pain in dogs.

• Maddison JE, Page SW, Church D (2002). Small Animal Clinical Pharmacology. Elsevier Health Sciences. pp. 260–1. ISBN 978-0702025730.

The main effect of toxicity in dogs is liver damage, and GI ulceration has been reported.

• Richardson JA (2000). “Management of acetaminophen and ibuprofen toxicoses in dogs and cats” (PDF). Journal of Veterinary Emergency and Critical Care. 10 (4): 285–91. doi:10.1111/j.1476-4431.2000.tb00013.x. Archived from the original (PDF) on 1 April 2010.
• Villar D, Buck WB, Gonzalez JM (June 1998). “Ibuprofen, aspirin and acetaminophen toxicosis and treatment in dogs and cats”. Veterinary and Human Toxicology. 40 (3): 156–62. PMID 9610496.
• Gwaltney-Brant S, Meadows I (March 2006). “The 10 Most Common Toxicoses in Dogs”. Veterinary Medicine: 142–8. Archived from the original on 10 July 2011. Retrieved 28 October 2019.
• Dunayer E (2004). “Ibuprofen toxicosis in dogs, cats, and ferrets”. Veterinary Medicine: 580–6. Archived from the original on 10 July 2011.

N-acetylcysteine treatment is efficacious in dogs when administered within two hours of paracetamol ingestion.

• Richardson JA (2000). “Management of acetaminophen and ibuprofen toxicoses in dogs and cats” (PDF). Journal of Veterinary Emergency and Critical Care. 10 (4): 285–91. doi:10.1111/j.1476-4431.2000.tb00013.x. Archived from the original (PDF) on 1 April 2010.
• Maddison JE, Page SW, Church D (2002). Small Animal Clinical Pharmacology. Elsevier Health Sciences. pp. 260–1. ISBN 978-0702025730.