Konzo is an epidemic paralytic disease reportedly from simultaneous malnutrition and high dietary cyanide intake

Konzo is an epidemic paralytic disease occurring among hunger-stricken rural populations in Africa where a diet dominated by insufficiently processed cassava results in simultaneous malnutrition and high dietary cyanide intake. 

Konzo was first described by Giovanni Trolli in 1938 who compiled the observations from eight doctors working in the Kwango area of the Belgian Congo (now Democratic Republic of the Congo).

  • Trolli, Giovanni (1938). “Résumé des observations réunies, au Kwango, au sujet de deux affections d’origine indeterminee: Paraplégie spastique épidémique, ‘Konzo’des indigènes du Kwango” (in French). Fonds Reine Elisabeth, Brussels.

“Konzo” means “tied legs” in the Yaka language in Southwestern DR Congo and was the designation by the first affected population in DR Congo as reported by Dr G. Trolli in 1938. The name, taken up by Hans Rosling and colleagues, aptly describes the typical spastic gait of those affected.

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