Adamalysin II, the protein world’s very own Eastern diamondback rattlesnake superstar

Adamalysin II and its unexpected rendezvous with mammalian reproductive tracts – how nature took a venomous snake and turned its deadly bite into a blueprint for life itself

a snake venom metalloproteinase has a surprising connection to mammalian reproductive tracts through structural and functional similarities:

Overall Structure

Active Site

Comparison with Other Metalloproteinases

inspired by Refined 2.0 A X-ray crystal structure of the snake venom zinc-endopeptidase adamalysin II. Primary and tertiary structure determination, refinement, molecular structure and comparison with astacin, collagenase and thermolysin

Abstract

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