Thiocyanate (Redox) pub med search

[Mechanism of Thiocyanate Dehydrogenase Functioning Based on Structural Data].

Polyakov KM, Gavryushov S.Mol Biol (Mosk). 2025 Jan-Feb;59(1):141-153.PMID: 40542637 Russian.

Thiocyanate dehydrogenase is enzyme catalyzing transformation of a thiocyanate ion into a cyanate ion with outcome of two electrons, two protons and a neutral atom of sulphur. …The complex with thiourea allows us to model binding of thiocyanate ion to the e …2Cite 

Lactoperoxidase: Properties, Functions, and Potential Applications.

Özhan HK, Duman H, Bechelany M, Karav S.Int J Mol Sci. 2025 May 24;26(11):5055. doi: 10.3390/ijms26115055.PMID: 40507866 Free PMC article. Review.

It catalyzes the oxidation of certain molecules such as thiocyanate (SCN(-)), I(-), and Br(-) in the presence of hydrogen peroxide (H(2)O(2)). This reaction leads to the formation of antimicrobial products that have a great antimicrobial spectrum, including antibacterial, …3Cite 

Cooperative Photometallobiocatalysis: Nonheme Fe Enzyme-Catalyzed Enantioconvergent Radical Decarboxylative Azidation, Thiocyanation, and Isocyanation of Redox-Active Esters.

Zhao LP, Lin K, Xie PP, Liu H, Xiang H, Liu X, Zhao Y, Liu P, Yang Y.Angew Chem Int Ed Engl. 2025 May 14:e202506361. doi: 10.1002/anie.202506361. Online ahead of print.PMID: 40366276

Herein, we report cooperative photobiocatalysis involving an engineered nonheme Fe enzyme and a tailored photoredox catalyst to achieve enantioconvergent decarboxylative azidation, thiocyanation, and isocyanation of redox-active esters via a radical mechanism. We re …4Cite 

Rotation of Hexamethylenetetramine Molecules Induces Reversible Electromagnetic Coupling Properties in Isothiocyanato-Nickel Complexes.

Abuduheni A, Zhou L, Yao Y, Liu Y, Hu H, Liu Z.Int J Mol Sci. 2025 Apr 25;26(9):4050. doi: 10.3390/ijms26094050.PMID: 40362290 Free PMC article.

In this study, a novel functional material with electromagnetic coupling properties [Ni(NCS)(4)(C(6)H(13)N(4))(2)] (1) was obtained by naturally evaporating an aqueous solution of nickel chloride hexahydrate, hexamethylenetetramine (HMTA), and potassium thiocyanate as raw …5Cite 

Molecular engineering and electrolyte optimization strategies for enhanced performance of Ru(ii) polypyridyl-sensitized DSSCs.

Abdellah IM.RSC Adv. 2025 Mar 31;15(13):9763-9786. doi: 10.1039/d5ra01470k. eCollection 2025 Mar 28.PMID: 40165914 Free PMC article. Review.

In addition, cyclometallated polypyridyl Ru(ii) complexes are explored as promising alternatives to Ru(ii) complexes incorporating labile thiocyanate (SCN) ligands for DSSCs, which offer improved stability. The relationship between the molecular structure of Ru(ii) photose …6Cite 

The stability of isothiocyanates in broccoli extract: Oxidation from erucin to sulforaphane was discovered.

Song F, Verheust Y, Sampers I, Raes K.Food Chem. 2025 Jul 15;480:143872. doi: 10.1016/j.foodchem.2025.143872. Epub 2025 Mar 14.PMID: 401203117Cite 

Array of Manganese-Based Bimetallic Metal-Organic-Framework Nanozymes with Enhanced Oxidase-like Catalytic Activity Can Simultaneously Identify and Measure Antioxidants.

Heidary O, Ashrafi H, Akhond M, Hemmateenejad B.Anal Chem. 2025 Mar 11;97(9):4860-4870. doi: 10.1021/acs.analchem.4c03942. Epub 2025 Feb 26.PMID: 40011249

The catalysts exhibit a wide range of highly potent oxidase-like catalytic activities, as verified by kinetic parameters, due to the presence of highly dispersed transition metallic and bimetallic redox nodes. These nanozymes efficiently catalyze the oxidation of colorless …8Cite 

MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation.

Santiago MJ, Chinnapaiyan S, Panda K, Rahman MS, Ghorai S, Lucas JH, Black SM, Rahman I, Unwalla HJ.J Inflamm (Lond). 2024 Aug 27;21(1):31. doi: 10.1186/s12950-024-00405-x.PMID: 39192275 Free PMC article.

Additionally, the LPO system potentially aids in maintaining cellular redox balance by reducing the levels of H(2)O(2), thus mitigating oxidative stress within the airway epithelium. …This paper demonstrates a new mechanism by which TGF-beta1 can lead to altered redox …9Cite 

One-stage anammox and thiocyanate-driven autotrophic denitrification for simultaneous removal of thiocyanate and nitrogen: Pathway and mechanism.

Chen X, Duan F, Yu X, Xie Y, Wang Z, El-Baz A, Ni BJ, Ni SQ.Water Res. 2024 Nov 1;265:122268. doi: 10.1016/j.watres.2024.122268. Epub 2024 Aug 21.PMID: 39173358

However, the research on the coupled process for removing naturally toxic thiocyanate (SCN(-)) is limited. This work successfully established and operated a one-stage coupled system by co-cultivating mature anammox and SCN(-)-driven autotrophic denitrification sludge in a …10Cite 

Resistance of Pseudomonas aeruginosa and Staphylococcus aureus to the airway epithelium oxidative response assessed by a cell-free in vitro assay.

Petithomme-Nanrocki M, Nicolau-Guillaumet N, Borie N, Haudrechy A, Renault JH, Moussalih S, Muggeo A, Guillard T.PLoS One. 2024 Aug 14;19(8):e0306259. doi: 10.1371/journal.pone.0306259. eCollection 2024.PMID: 39141636 Free PMC article.11Cite 

Physicochemical properties, biological chemistry and mechanisms of action of caries-arresting diammine-silver(I) fluoride and silver(I)-fluoride solutions for clinical use: a critical review.

Hunwin K, Page G, Edgar M, Botana A, Armitage R, Bhogadia M, Desai U, Duffin S, Duffin M, Chan W, Grootveld M.Front Oral Health. 2024 Jul 23;5:1412751. doi: 10.3389/froh.2024.1412751. eCollection 2024.PMID: 39108636 Free PMC article. Review.

Such reactions were found to slowly promote the generation of potentially physiologically-active Ag/AgCl nanoparticles from primarily-generated discoloured silver(I) chloride (AgCl) precipitates, a process involving salivary electron-donors such as thiocyanate and L-cystei …12Cite 

The role of metals in hypothiocyanite resistance in Escherichia coli.

Gray MJ.J Bacteriol. 2024 Aug 22;206(8):e0009824. doi: 10.1128/jb.00098-24. Epub 2024 Jul 17.PMID: 39016617 Free PMC article.

These results advance our understanding of the contribution of different oxidative stress responses and redox buffering pathways to HOSCN resistance in E. coli and illustrate important interactions between metal ions and the enzymes bacteria use to defend themselves agains …13Cite 

Photocascade chemoselective controlling of ambident thio(seleno)cyanates with alkenes via catalyst modulation.

Hoque IU, Samanta A, Pramanik S, Chowdhury SR, Lo R, Maity S.Nat Commun. 2024 Jul 9;15(1):5739. doi: 10.1038/s41467-024-49279-w.PMID: 38982050 Free PMC article.

Controlling the ambident reactivity of thiocyanates in reaction manifolds has been a long-standing and formidable challenge. We report herein a photoredox strategy for installing thiocyanates and isothiocyanates in a controlled chemoselective fashion by manipulating …14Cite 

A Metastable Semiquinone Molecular Switch Modulated by Ascorbate/O₂: A Study from a System Far-From-Equilibrium to Biological Assays in Mitochondria.

Rodríguez-Valdez G, Martínez-Cerda ME, Mejía-Reyes JG, Tapia-Juárez M, Olmos-Orizaba E, Cortés-Rojo C, Cortés-García CJ, Contreras-Celedón CA, Solorio-Alvarado CR, Chacón-García L.Chembiochem. 2024 Sep 16;25(18):e202400401. doi: 10.1002/cbic.202400401. Epub 2024 Sep 3.PMID: 38981854

A molecular switch based on the metastable radical anion derived from a substituted heteroaryl quinone is described. Pyrrolyl quinone thiocyanate (PQ 9) showed an interaction with the fluoride anion that was visible to the naked eye and quantified by UV/vis and 1H and 13 C …15Cite 

Exploring the synergy between copper electrolytes and molecularly engineered thiocyanate-free cyclometalated ruthenium sensitizers for dye-sensitized solar cells.

M M S, Pradhan SC, George AS, P R N, Mishra RK, John J, Soman S.Photochem Photobiol. 2024 Jul-Aug;100(4):1127-1139. doi: 10.1111/php.13984. Epub 2024 Jun 23.PMID: 38922730

Two novel cyclometalated ruthenium complexes, RC-4 and RC-5, featuring 1-phenylisoquinoline and phenyl quinazoline as ancillary ligands, respectively, were synthesized to investigate their viability with the environmentally friendly copper (Cu) redox mediator, [Cu(bpye)(2) …16Cite 

Redox Relay-Induced C-S Radical Cross-Coupling Strategy: Application in Nontraditional Site-Selective Thiocyanation of Quinoxalinones.

Shi SH, Li HY, Liu HY, Tian R, Zhu HT.J Org Chem. 2024 May 17;89(10):6826-6837. doi: 10.1021/acs.joc.4c00215. Epub 2024 Apr 26.PMID: 38669146

However, oxidative cross-coupling for constructing C-S bond is still a challenge due to sulfur overoxidation and poisoning transition-metal catalysts. Now, electrochemical redox relay using sulfur radicals formed in situ from inorganic sulfur source offers a solution to th …17Cite 

The therapeutic potential of thiocyanate and hypothiocyanous acid against pulmonary infections.

Ashtiwi NM, Kim SO, Chandler JD, Rada B.Free Radic Biol Med. 2024 Jul;219:104-111. doi: 10.1016/j.freeradbiomed.2024.04.217. Epub 2024 Apr 11.PMID: 38608822 Free PMC article. Review.

Hypothiocyanous acid (HOSCN) is an endogenous oxidant produced by peroxidase oxidation of thiocyanate (SCN(-)), an ubiquitous sulfur-containing pseudohalide synthesized from cyanide. …18Cite 

Hypothiocyanous acid reductase is critical for host colonization and infection by Streptococcus pneumoniae.

Shearer HL, Currie MJ, Agnew HN, Trappetti C, Stull F, Pace PE, Paton JC, Dobson RCJ, Dickerhof N.J Biol Chem. 2024 May;300(5):107282. doi: 10.1016/j.jbc.2024.107282. Epub 2024 Apr 9.PMID: 38604564 Free PMC article.19Cite 

Three Oxidation States of Cobalt(I/II/III) Complexes by Thiaporphyrin.

Wang F, Zhong ZB, Jia RX, Xing K, Cao R, Bai F, Duan PC.Inorg Chem. 2024 Apr 22;63(16):7233-7240. doi: 10.1021/acs.inorgchem.3c04491. Epub 2024 Apr 8.PMID: 38588385

These two allowed the development of one electron reduction and oxidation to give [Co(I)(STTP)] (3), [Co(III)(STTP)Cl(CH(3)CN)](BF(4)) (4), and [Co(III)(STTP)Cl(2)] (5). The products of the chemical redox reactions were isolated and fully characterized. In addition, the re …20Cite 

Inorganic-Organic Dual-Ligand-Regulated Photocatalysis of CdS@Zn_xCd_1-xS@ZnS Quantum Dots for Lignin Valorization.

Guo Y, Chen X, Liu Y, Chen Z, Guo P, Luo D, Zhang M, Liu X.ACS Appl Mater Interfaces. 2024 Mar 13;16(10):12624-12636. doi: 10.1021/acsami.3c18957. Epub 2024 Feb 28.PMID: 38419339

Herein, an efficient and facile ligand manipulating strategy to balance the redox reaction process is exploited via decorating the surface of the CdS@Zn(x)Cd(1-x)S@ZnS gradient-alloyed quantum dots with both inorganic ligands of hexafluorophosphate (PF(6)(-)) and organic l …21Cite 

Thiosulfate sulfurtransferase deficiency promotes oxidative distress and aberrant NRF2 function in the brain.

Luo Y, Chatre L, Melhem S, Al-Dahmani ZM, Homer NZM, Miedema A, Deelman LE, Groves MR, Feelisch M, Morton NM, Dolga A, van Goor H.Redox Biol. 2023 Dec;68:102965. doi: 10.1016/j.redox.2023.102965. Epub 2023 Nov 19.PMID: 38000344 Free PMC article.

Thiosulfate sulfurtransferase (TST, EC 2.8.1.1) was discovered as an enzyme that detoxifies cyanide by conversion to thiocyanate (rhodanide) using thiosulfate as substrate; this rhodanese activity was subsequently identified to be almost exclusively located in mitochondria …22Cite 

Organophotocatalyzed Mono- and Bis-Alkyl/Difluoroalkylative Thio/Selenocyanation of Alkenes.

Pal K, Chandu P, Das D, Jinilkumar AV, Mallick M, Sureshkumar D.J Org Chem. 2023 Dec 15;88(24):17527-17537. doi: 10.1021/acs.joc.3c02102. Epub 2023 Nov 21.PMID: 37988569

Organophotocatalyzed three-component 1,2-difluoroacetyl/alkyl/perfluoroalkylative thio/selenocyanation of styrene derivatives under stoichiometric, transition metal-, oxidant-, and additive-free, and mild redox-neutral conditions is reported. Organophotocatalyst 4CzIPN ope …23Cite 

Sulfur oxidation kinetics of Acidithiobacillus caldus and its inhibition on exposure to thiocyanate present in cyanidation tailings wastewater.

Edward CJ, Smart M, Kotsiopoulos A, Harrison STL.Res Microbiol. 2024 Jan-Feb;175(1-2):104134. doi: 10.1016/j.resmic.2023.104134. Epub 2023 Sep 28.PMID: 37777032 Free article.

The sulfur oxidation kinetics of an industrial strain of Acidithiobacillus caldus (At. caldus) cultured on elemental sulfur was explored in batch experiments in the absence and presence of thiocyanate (SCN(-)), a toxin inherent within cyanidation tailings wastewater. The C …24Cite 

Fine-Tuning of the Optical and Electrochemical Properties of Ruthenium(II) Complexes with 2-Arylbenzimidazoles and 4,4′-Dimethoxycarbonyl-2,2′-bipyridine.

Lavrova MA, Verzun SA, Mishurinskiy SA, Sirotin MA, Bykova SK, Gontcharenko VE, Mariasina SS, Korshunov VM, Taydakov IV, Belousov YA, Dolzhenko VD.Molecules. 2023 Sep 9;28(18):6541. doi: 10.3390/molecules28186541.PMID: 37764316 Free PMC article.

With an increase in substituent donation, a red shift of the absorption and emission bands occurs, and the lifetime of the excited state and the redox potential of the complex decrease. The combination of these properties shows that the complexes are excellent dyes and can …25Cite 

Characterization of the active site in the thiocyanate-forming protein from Thlaspi arvense (TaTFP) using EPR spectroscopy.

Hashemi Haeri H, Schneegans N, Eisenschmidt-Bönn D, Brandt W, Wittstock U, Hinderberger D.Biol Chem. 2023 Aug 17;405(2):105-118. doi: 10.1515/hsz-2023-0187. Print 2024 Feb 26.PMID: 37586381

Upon tissue damage, their myrosinase-catalyzed hydrolysis yields aglucones that rearrange to toxic isothiocyanates. Specifier proteins such as thiocyanate-forming protein from Thlaspi arvense (TaTFP) are non-heme iron proteins, which capture the aglucone to form alternativ …26Cite 

Simultaneous determination of intracellular reduced and oxidized glutathiones by the König reaction.

Mochizuki R, Kobayashi A, Takayama H, Toida T, Ogra Y.Anal Methods. 2023 Jul 20;15(28):3426-3431. doi: 10.1039/d3ay00860f.PMID: 37427721

The Konig reaction is commonly used for the detection of cyanide and its derivatives, including thiocyanate and selenocyanate. We found that this reaction can be used to quantify glutathione fluorometrically, and applied it to the simultaneous determination of reduced and …27Cite 

Substrate-dependent metabolomic signatures of myeloperoxidase activity in airway epithelial cells: Implications for early cystic fibrosis lung disease.

Kim SO, Shapiro JP, Cottrill KA, Collins GL, Shanthikumar S, Rao P, Ranganathan S, Stick SM, Orr ML, Fitzpatrick AM, Go YM, Jones DP, Tirouvanziam RM, Chandler JD.Free Radic Biol Med. 2023 Sep;206:180-190. doi: 10.1016/j.freeradbiomed.2023.06.021. Epub 2023 Jun 23.PMID: 37356776 Free PMC article.

Myeloperoxidase (MPO) is released by neutrophils in inflamed tissues. MPO oxidizes chloride, bromide, and thiocyanate to produce hypochlorous acid (HOCl), hypobromous acid (HOBr), and hypothiocyanous acid (HOSCN), respectively. …Continued research with this exposure mode …28Cite 

The efficient utilization of thiocyanate on simultaneous removal of ammonium and nitrate through thiosulfate-driven autotrophic denitrifiers and anammox.

Liu L, Xu Y, Yu C, Pan H, Wei C, Zhao X, Su M, Pan J.Bioresour Technol. 2023 Jul;380:129069. doi: 10.1016/j.biortech.2023.129069. Epub 2023 Apr 21.PMID: 37086926

The efficient utilization of thiocyanate remain be an important bottleneck in the low-cost nitrogen removal for wastewaters containing thiocyanate. …The results showed that removal of nitrate and ammonium were achieved rapidly utilizing thiocyanate, which w …29Cite 

Facile route of heterostructure CeO₂-CuO nanocomposite as an efficient electron transport material for perovskite solar cells.

Manibalan G, Murugadoss G, Jayavel R, Rajesh Kumar M, Pugazhendhi A.Environ Res. 2023 Jul 1;228:115853. doi: 10.1016/j.envres.2023.115853. Epub 2023 Apr 12.PMID: 37059326

In this present paper, first time we have demonstrated that the CeO(2)-CuO composite as an electron transport material (ETM) with copper (I) thiocyanate (CuSCN) as hole transport material (HTM) for the perovskite solar cells device fabrication. …30Cite 

Plasma hydrogen sulfide, nitric oxide, and thiocyanate levels are lower during pregnancy compared to postpartum in a cohort of women from the Pacific northwest of the United States.

Zeigler MB, Fay EE, Moreni SL, Mao J, Totah RA, Hebert MF.Life Sci. 2023 Jun 1;322:121625. doi: 10.1016/j.lfs.2023.121625. Epub 2023 Mar 30.PMID: 37001802 Free PMC article.

AIMS: Pregnancy alters multiple physiological processes including angiogenesis, vasodilation, inflammation, and cellular redox, which are partially modulated by the gasotransmitters hydrogen sulfide (H(2)S) and nitric oxide (NO). In this study, we sought to determine how p …31Cite 

Visible-light-induced C(sp(3))-H thiocyanation of pyrazolin-5-ones: a practical synthesis of 4-thiocyanated 5-hydroxy-1H-pyrazoles.

Hu X, Guo H, Jiang H, Zheng R, Zhou Y, Wang L.Org Biomol Chem. 2023 Mar 8;21(10):2232-2235. doi: 10.1039/d3ob00092c.PMID: 36810647

A direct, aerobic and visible light photocatalytic approach to synthesize 4-thiocyanated 5-hydroxy-1H-pyrazoles via cross-coupling of pyrazolin-5-ones with ammonium thiocyanate is described. Under redox-neutral and metal-free conditions, a series of 4-thio …32Cite 

Oxoammonium Salt-Promoted Multifunctionalization of Saturated Cyclic Amines Based On β-Oxo Cyclic Iminium Ion Intermediates.

He Y, Liu Q, Yang J, Zheng Z, Chai GL, Zhang X, Fan X.Org Lett. 2022 Oct 28;24(42):7839-7844. doi: 10.1021/acs.orglett.2c03253. Epub 2022 Oct 20.PMID: 36264018

Herein we describe a convenient method for multiple C(sp(3))-H bond functionalization of saturated cyclic amines through oxoammonium salt-promoted oxidation to afford a beta-oxo cyclic iminium ion as a key intermediate, followed by cascade addition with thiocyanate and div …33Cite 

Unusual Cytochrome c552 from Thioalkalivibrio paradoxus: Solution NMR Structure and Interaction with Thiocyanate Dehydrogenase.

Britikov VV, Bocharov EV, Britikova EV, Dergousova NI, Kulikova OG, Solovieva AY, Shipkov NS, Varfolomeeva LA, Tikhonova TV, Timofeev VI, Shtykova EV, Altukhov DA, Usanov SA, Arseniev AS, Rakitina TV, Popov VO.Int J Mol Sci. 2022 Sep 1;23(17):9969. doi: 10.3390/ijms23179969.PMID: 36077365 Free PMC article.

The search of a putative physiological electron acceptor for thiocyanate dehydrogenase (TcDH) newly discovered in the thiocyanate-oxidizing bacteria Thioalkalivibrio paradoxus revealed an unusually large, single-heme cytochrome c (CytC552), which was co-purified wit …34Cite 

Escherichia coli RclA is a highly active hypothiocyanite reductase.

Meredith JD, Chapman I, Ulrich K, Sebastian C, Stull F, Gray MJ.Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2119368119. doi: 10.1073/pnas.2119368119. Epub 2022 Jul 22.PMID: 35867824 Free PMC article.

We have found, in Escherichia coli, that the flavoprotein RclA, previously implicated in reactive chlorine resistance, reduces HOSCN to thiocyanate with near-perfect catalytic efficiency and strongly protects E. coli against HOSCN toxicity. …35Cite 

Photochemical C(sp)(2)-H bond thiocyanation and selenocyanation of activated arenes, batch and continuous-flow approaches.

Lemir ID, Oksdath-Mansilla G, Castro-Godoy WD, Schmidt LC, Argüello JE.Photochem Photobiol Sci. 2022 May;21(5):849-861. doi: 10.1007/s43630-021-00167-y. Epub 2022 Feb 3.PMID: 35113403

Herein, we report an eco-friendly photochemical oxidative C(sp)(2)-H thiocyanation and selenocyanation of activated arenes. The reaction proceeds under Violet LED irradiation in the presence of K(2)S(2)O(8), which quickly oxidizes KSCN and KSeCN, finally producing arylthio …36Cite 

Structural evidence of the oxidation of iodide ion into hyper-reactive hypoiodite ion by mammalian heme lactoperoxidase.

Singh PK, Ahmad N, Yamini S, Singh RP, Singh AK, Sharma P, Smith ML, Sharma S, Singh TP.Protein Sci. 2022 Feb;31(2):384-395. doi: 10.1002/pro.4230. Epub 2021 Nov 18.PMID: 34761444 Free PMC article.

To perform its innate immune action against invading microbes, LPO utilizes hydrogen peroxide (H(2) O(2) ) to convert thiocyanate (SCN(-) ) and iodide (I(-) ) ions into the oxidizing compounds hypothiocyanite (OSCN(-) ) and hypoiodite (IO(-) ). …37Cite 

Evaluation of canonical choline chloride based deep eutectic solvents as dye-sensitized solar cell electrolytes.

Boogaart DJ, Essner JB, Baker GA.J Chem Phys. 2021 Aug 14;155(6):061102. doi: 10.1063/5.0055644.PMID: 34391350

To begin to address this deficiency in understanding, we performed a comprehensive characterization of the three “canonical” choline chloride-based DESs (i.e., reline, ethaline, and glyceline) as DSSC electrolytes hosting the iodide-triiodide (I(-)/I(3) (-)) redox couple. …38Cite 

Deletion of the lactoperoxidase gene causes multisystem inflammation and tumors in mice.

Yamakaze J, Lu Z.Sci Rep. 2021 Jun 14;11(1):12429. doi: 10.1038/s41598-021-91745-8.PMID: 34127712 Free PMC article.

Strongly oxidative H(2)O(2) is biologically important, but if uncontrolled, would lead to tissue injuries. Lactoperoxidase (LPO) catalyzes the redox reaction of reducing highly reactive H(2)O(2) to H(2)O while oxidizing thiocyanate (SCN(-)) to relatively tissue-inno …39Cite 

Hexaferrocenium tri[hexa(isothiocyanato)iron(III)] trihydroxonium complex as a new DNA intercalator for electrochemical DNA biosensor.

Ariffin EY, Zakariah EI, Ruslin F, Kassim M, Yamin BM, Heng LY, Hasbullah SA.Sci Rep. 2021 Apr 12;11(1):7883. doi: 10.1038/s41598-021-86939-z.PMID: 33846405 Free PMC article.

Ferrocene or ferrocenium has been widely studied in the field of organometallic complexes because of its stable thermodynamic, kinetic and redox properties. Novel hexaferrocenium tri[hexa(isothiocyanato)iron(III)]trihydroxonium (HexaFc) complex was the product from the rea …40Cite 

Catalytic Properties of Flavocytochrome c Sulfide Dehydrogenase from Haloalkaliphilic Bacterium Thioalkalivibrio paradoxus.

Tikhonova TV, Lilina AV, Osipov EM, Shipkov NS, Dergousova NI, Kulikova OG, Popov VO.Biochemistry (Mosc). 2021 Mar;86(3):361-369. doi: 10.1134/S0006297921030111.PMID: 33838635 Free article.

The Thioalkalivibrio paradoxus ARh1 genome contains five copies of genes encoding homologous FCCs with an amino acid sequence identity from 36 to 54%. When growing on thiocyanate or thiosulfate as the main energy source, the bacterium synthesizes products of different copi …41Cite 

Antioxidant activity of two edible isothiocyanates: Sulforaphane and erucin is due to their thermal decomposition to sulfenic acids and methylsulfinyl radicals.

Cedrowski J, Dąbrowa K, Przybylski P, Krogul-Sobczak A, Litwinienko G.Food Chem. 2021 Aug 15;353:129213. doi: 10.1016/j.foodchem.2021.129213. Epub 2021 Feb 1.PMID: 33774519 Free article.

Their chemopreventive and anticancer activity is attributed to ability to modulate cellular redox status due to induction of Phase 2 cytoprotective enzymes (indirect antioxidant action) but many attempts to connect the bioactivity of ITCs with their radical trapping activi …42Cite 

Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues.

Flouda K, Gammelgaard B, Davies MJ, Hawkins CL.Redox Biol. 2021 May;41:101873. doi: 10.1016/j.redox.2021.101873. Epub 2021 Jan 21.PMID: 33550113 Free PMC article.

This has sparked interest in the development of therapeutic approaches that decrease HOCl formation during chronic inflammation, including the use of alternative MPO substrates. Thiocyanate (SCN(-)) supplementation decreases HOCl production by favouring formation of hypoth …43Cite 

A sensitive, high-throughput fluorescent method for the determination of lactoperoxidase activities in milk and comparison in human, bovine, goat and camel milk.

Zou Z, Bauland J, Hewavitharana AK, Al-Shehri SS, Duley JA, Cowley DM, Koorts P, Shaw PN, Bansal N.Food Chem. 2021 Mar 1;339:128090. doi: 10.1016/j.foodchem.2020.128090. Epub 2020 Sep 16.PMID: 33152878

The traditional method for LPO activity measurement using ABTS (2,2′-azinobis(3-ethylbenzothiazoline-6-sulphonate) cannot achieve high sensitivity and is affected by indigenous milk thiocyanate. A more sensitive microplate fluorescent assay was developed by monitoring gene …44Cite 

Photoredox chemistry in the synthesis of 2-aminoazoles implicated in prebiotic nucleic acid synthesis.

Liu Z , Wu LF , Bond AD , Sutherland JD .Chem Commun (Camb). 2020 Nov 14;56(88):13563-13566. doi: 10.1039/d0cc05752e. Epub 2020 Oct 14.PMID: 33151212 Free PMC article.

Thiourea itself is produced by heating ammonium thiocyanate, a product of the reaction of HCN and hydrogen sulfide under UV irradiation….45Cite 

Structure and synthesis of copper-based Schiff base and reduced Schiff base complexes: a combined experimental and theoretical investigation of biomimetic catalytic activity.

Mandal A, Sarkar A, Adhikary A, Samanta D, Das D.Dalton Trans. 2020 Nov 10;49(43):15461-15472. doi: 10.1039/d0dt02784g.PMID: 33141130

Complexes 1 and 2 have 1D polymeric chain-like structures bridging through thiocyanate and azide anions, whereas complex 3 has a mononuclear structure in the solid state. …EPR studies confirmed that for complex 1, the OAP oxidation goes through the generation of an organ …46Cite 

The Role of Thiocyanate in Modulating Myeloperoxidase Activity during Disease.

San Gabriel PT, Liu Y, Schroder AL, Zoellner H, Chami B.Int J Mol Sci. 2020 Sep 3;21(17):6450. doi: 10.3390/ijms21176450.PMID: 32899436 Free PMC article. Review.

Thiocyanate (SCN(-)) is a pseudohalide anion omnipresent across mammals and is particularly concentrated in secretions within the oral cavity, digestive tract and airway. Thiocyanate can outcompete chlorine anions and other halides (F(-), Br(-), I(-)) as substrates …47Cite 

Comparing DPPP fluorescence and UV based methods to assess oxidation degree of krill oil-in-water emulsions.

Uluata S, Durmaz G, Julian McClements D, Decker EA.Food Chem. 2021 Mar 1;339:127898. doi: 10.1016/j.foodchem.2020.127898. Epub 2020 Aug 27.PMID: 32871303

In this study, lipid oxidation evaluation methods were compared for a krill-oil-in-water emulsion system. With this aim, thiocyanate and DPPP (diphenyl-1-pyrenylphosphine) fluorescence methods were comparatively examined to determine primary oxidation products. 2-thiobarbi …48Cite 

The Study of Plasticized Amorphous Biopolymer Blend Electrolytes Based on Polyvinyl Alcohol (PVA): Chitosan with High Ion Conductivity for Energy Storage Electrical Double-Layer Capacitors (EDLC) Device Application.

Aziz SB, M Hadi J, Dannoun EMA, Abdulwahid RT, R Saeed S, Shahab Marf A, Karim WO, Kadir MFZ.Polymers (Basel). 2020 Aug 27;12(9):1938. doi: 10.3390/polym12091938.PMID: 32867191 Free PMC article.

In this study, plasticized films of polyvinyl alcohol (PVA): chitosan (CS) based electrolyte impregnated with ammonium thiocyanate (NH(4)SCN) were successfully prepared using a solution-casting technique. The structural features of the electrolyte films were investigated t …49Cite 

Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN(-)).

Vanichkitrungruang S, Chuang CY, Hawkins CL, Davies MJ.Redox Biol. 2020 Sep;36:101641. doi: 10.1016/j.redox.2020.101641. Epub 2020 Jul 9.PMID: 32863239 Free PMC article.

The effect of increasing concentrations of the alternative MPO substrate thiocyanate (SCN(-)), which might decrease HOCl formation were also examined. Exposure of fibronectin to MPO/H(2)O(2)/Cl(-) is shown to result in damage to the functionally important cell-binding and …50Cite 

Anammox reactor exposure to thiocyanate: Long-term performance and microbial community dynamics.

Yu X, Nishimura F, Hidaka T.Bioresour Technol. 2020 Dec;317:123960. doi: 10.1016/j.biortech.2020.123960. Epub 2020 Aug 5.PMID: 32822893

The present study estimated the effects of thiocyanate (SCN(-)), a common pollutant in coking wastewaters, on anammox processes and microbial communities in anammox reactors for over two years of continuous exposure. …51Cite 

Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages.

Guo C, Davies MJ, Hawkins CL.Redox Biol. 2020 Sep;36:101666. doi: 10.1016/j.redox.2020.101666. Epub 2020 Jul 31.PMID: 32781424 Free PMC article.

As such, there is increasing interest in the use of thiocyanate (SCN(-)) therapeutically to decrease inflammatory disease, as SCN(-) is the favoured substrate for MPO, and a potent competitive inhibitor of HOCl formation. …52Cite 

Simultaneous removal of nitrate and heavy metals in a continuous flow nitrate-dependent ferrous iron oxidation (NDFO) bioreactor.

Jokai K, Nakamura T, Okabe S, Ishii S.Chemosphere. 2021 Jan;262:127838. doi: 10.1016/j.chemosphere.2020.127838. Epub 2020 Aug 1.PMID: 32768756

However, when the reactor is fed with coke-oven wastewater supplemented with 10 mM nitrate, 5 mM Fe(II), 4 mM acetate, and 10 mg/L ZnCl(2), the reactor performance significantly decreased, most likely due to the inhibition of bacterial growth by thiocyanate or organic cont …53Cite 

Oxidative killing of encapsulated and nonencapsulated Streptococcus pneumoniae by lactoperoxidase-generated hypothiocyanite.

Gingerich AD, Doja F, Thomason R, Tóth E, Bradshaw JL, Douglass MV, McDaniel LS, Rada B.PLoS One. 2020 Jul 30;15(7):e0236389. doi: 10.1371/journal.pone.0236389. eCollection 2020.PMID: 32730276 Free PMC article.

Airway epithelial cells, the primary responders to pneumococcal infection, orchestrate an extracellular antimicrobial system consisting of lactoperoxidase (LPO), thiocyanate anion and hydrogen peroxide (H2O2). LPO oxidizes thiocyanate using H2O2 into the final produ …54Cite 

Degradation of thiocyanate by electrochemical oxidation process in coke oven wastewater: Role of operative parameters and mechanistic study.

Turan A, Keyikoglu R, Kobya M, Khataee A.Chemosphere. 2020 Sep;255:127014. doi: 10.1016/j.chemosphere.2020.127014. Epub 2020 May 10.PMID: 32679632

This study presents the removal of thiocyanate (SCN(-)) from coke oven wastewater by the electrooxidation (EO) process. Initially, the performances boron-doped diamond (BDD) and different DSA (Dimensionally stable anode) electrodes including Ti/IrO(2), Ti/IrO(2)-RuO(2), an …55Cite 

Peroxidasin mediates bromination of tyrosine residues in the extracellular matrix.

Bathish B, Paumann-Page M, Paton LN, Kettle AJ, Winterbourn CC.J Biol Chem. 2020 Sep 4;295(36):12697-12705. doi: 10.1074/jbc.RA120.014504. Epub 2020 Jul 16.PMID: 32675287 Free PMC article.

The level of 3-bromotyrosine was significantly higher in extracellular matrix than intracellular proteins, although a low amount was detected intracellularly. 3-Bromotyrosine levels increased with higher bromide concentrations and decreased in the presence of physiological concen …56Cite 

Bioactive Sterol Derivatives Isolated from the Pleurotus djamor var. Roseus Induced Apoptosis in Cancer Cell Lines.

Jagadeesh R, Babu G, Lakshmanan H, Oh OM, Jang JK, Kong KW, Raaman N.Cardiovasc Hematol Agents Med Chem. 2020;18(2):124-134. doi: 10.2174/1871525718666200303123557.PMID: 32660409

In vitro lipid peroxidation activities of isolated compounds were determined by ferric thiocyanate (FTC) and thiobarbituric acid (TBA) method. The sterol derivatives C2 and C3 compounds displayed strong antioxidant activity and were not significantly different (p<0.05) …57Cite 

The role of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) in the induction of mitochondrial dysfunction in macrophages.

Love DT, Guo C, Nikelshparg EI, Brazhe NA, Sosnovtseva O, Hawkins CL.Redox Biol. 2020 Sep;36:101602. doi: 10.1016/j.redox.2020.101602. Epub 2020 Jun 10.PMID: 32570189 Free PMC article.

A host of chronic inflammatory diseases are accelerated by the formation of the powerful oxidant hypochlorous acid (HOCl) by myeloperoxidase (MPO). In the presence of thiocyanate (SCN(-)), the production of HOCl by MPO is decreased in favour of the formation of a milder ox …58Cite 

Diversity and uniformity in anion-pi complexes of thiocyanate with aromatic, olefinic and quinoidal pi-acceptors.

Wilson J , Maxson T , Wright I , Zeller M , Rosokha SV .Dalton Trans. 2020 Jul 7;49(25):8734-8743. doi: 10.1039/d0dt01654c. Epub 2020 Jun 18.PMID: 32555839

Combined experimental and computational studies revealed that all these complexes were formed by an attraction of the anion to the face of the pi-system, and the arrangements of thiocyanate followed the areas of the most positive potentials on the surfaces of the pi-accept …59Cite 

Antioxidant capacity of extract from Jiangtang Xiaozhi recipe in vitro.

Song W, Yuan Y, Yu N, Gu H, Zhou Y, Chen X, Wang S, Fan K, Ge Z, Jin L, Xu Y.J Tradit Chin Med. 2020 Jun;40(3):393-400. doi: 10.19852/j.cnki.jtcm.2020.03.005.PMID: 32506852

In vitro antioxidant assays were used in this experiment, including 1,1-Diphenyl-2-picrylhydrazyl free radical (DPPH) radical scavenging ability, 2-2′-Azinobis-(3-ethylbenzthiazoline-6-sul phonate (ABTS) radical scavenging ability, reducing power assay, fluorescence recovery afte …60Cite 

Switching the Switch: Ligand Induced Disulfide Formation in HDAC8.

Jänsch N, Sugiarto WO, Muth M, Kopranovic A, Desczyk C, Ballweg M, Kirschhöfer F, Brenner-Weiss G, Meyer-Almes FJ.Chemistry. 2020 Oct 15;26(58):13249-13255. doi: 10.1002/chem.202001712. Epub 2020 Sep 11.PMID: 32428298 Free PMC article.

PD-404,182 was shown to be a selective covalent inhibitor of HDAC8 that forms mixed disulfides with several cysteine residues and is also able to transform thiol groups to thiocyanates. Moreover, HDAC8 was shown to be regulated by a redox switch based on the reversi …61Cite 

Trinuclear copper biocatalytic center forms an active site of thiocyanate dehydrogenase.

Tikhonova TV, Sorokin DY, Hagen WR, Khrenova MG, Muyzer G, Rakitina TV, Shabalin IG, Trofimov AA, Tsallagov SI, Popov VO.Proc Natl Acad Sci U S A. 2020 Mar 10;117(10):5280-5290. doi: 10.1073/pnas.1922133117. Epub 2020 Feb 24.PMID: 32094184 Free PMC article.

Here we report the discovery and characterization of a previously undescribed copper center that forms the active site of a copper-containing enzyme thiocyanate dehydrogenase (suggested EC 1.8.2.7) that was purified from the haloalkaliphilic sulfur-oxidizing bacterium of t …62Cite 

Inhibition of the mitochondrial respiratory components (Complex I and Complex III) as stimuli to induce oxidative damage in Oryza sativa L. under thiocyanate exposure.

Lin YJ, Yu XZ, Li YH, Yang L.Chemosphere. 2020 Mar;243:125472. doi: 10.1016/j.chemosphere.2019.125472. Epub 2019 Nov 25.PMID: 3199589663Cite 

Effectiveness of reactive oxygen species generated from rGO/CdS QD heterostructure for photodegradation and disinfection of pollutants in waste water.

Afreen G, Shoeb M, Upadhyayula S.Mater Sci Eng C Mater Biol Appl. 2020 Mar;108:110372. doi: 10.1016/j.msec.2019.110372. Epub 2019 Nov 1.PMID: 31924024

A facile synthetic route is presented to produce reduced graphene oxide/CdS quantum dot (rGO/CdS QD) heterostructure by monowave-assisted solvothermal method where room temperature ionic liquid 1-ethyl-3-methylimidazolium thiocyanate serves as a “green” precursor. The prep …64Cite 

Interaction of iron ions with melanin.

Żądło AC, Sarna T.Acta Biochim Pol. 2019 Dec 11;66(4):459-462. doi: 10.18388/abp.2019_2889.PMID: 31826048 Free article.

One of the antioxidant roles of melanin is binding redox-active transition metal ions. The aim of this study was to examine the redox reactions accompanying iron binding by melanin. …The iron binding was examined by electron paramagnetic resonance (EPR) spectrosco …65Cite 

Foliar application is an effective method for incorporating selenium into peanut leaf proteins with antioxidant activities.

Gao Q, Liu ZH, Wu JL, Geng Y, Zhang Q, Tie M, Gu XJ, Tanokura M, Xue YL.Food Res Int. 2019 Dec;126:108617. doi: 10.1016/j.foodres.2019.108617. Epub 2019 Aug 12.PMID: 31732068

Their antioxidant activities were also evaluated using free radical scavenging assay, reducing power assay and ferric thiocyanate (FTC) test. As results, the PSPL exhibited potent DPPH radical (96.2%) and superoxide anion radical (98.4%) scavenging activities and showed st …66Cite 

Cyanate Induces Oxidative Stress Injury and Abnormal Lipid Metabolism in Liver through Nrf2/HO-1.

Hu L, Tian K, Zhang T, Fan CH, Zhou P, Zeng D, Zhao S, Li LS, Smith HS, Li J, Ran JH.Molecules. 2019 Sep 5;24(18):3231. doi: 10.3390/molecules24183231.PMID: 31491954 Free PMC article.

Usually, 0.8% of the molar concentration of urea is converted into cyanate, while myeloperoxidase (MPO) catalyzes the oxidation of thiocyanate to produce cyanate at the site of inflammation during smoking, inflammation, or exposure to environmental pollution. …67Cite 

Antioxidant and Protective Effects of Atrina Pectinata Extract.

Kim YS, Kim EK, Dong X, Shin WB, Park JS, Kim SJ, Go EA, Byun HG, Park PJ.Adv Exp Med Biol. 2019;1155:627-641. doi: 10.1007/978-981-13-8023-5_56.PMID: 31468436

Lipid peroxidation inhibitory activity was confirmed using ferric thiocyanate and thiobarbituric acid assays. Furthermore, the protective effect of the A. pectinata extract against t-BHP-induced oxidative stress on Chang cells were evaluated using MTT assay and the measure …68Cite 

Modelling of simultaneous nitrogen and thiocyanate removal through coupling thiocyanate-based denitrification with anaerobic ammonium oxidation.

Chen X, Yang L, Sun J, Dai X, Ni BJ.Environ Pollut. 2019 Oct;253:974-980. doi: 10.1016/j.envpol.2019.07.104. Epub 2019 Jul 20.PMID: 31352189

Thiocyanate (SCN(-))-based autotrophic denitrification (AD) has recently been demonstrated as a promising technology that could be integrated with anaerobic ammonium oxidation (Anammox) to achieve simultaneous removal of nitrogen and SCN(-). …69Cite 

Application of transition metal ions in a study of photoinduced modifications of melanin.

Żądło AC.Acta Biochim Pol. 2019 May 16;66(2):237-241. doi: 10.18388/abp.2018_2802.PMID: 31095651 Free article.

The interaction of melanin with metal ions was examined by electron paramagnetic resonance (EPR) spectroscopy and a thiocyanate assay. Weak photodegradation of melanin was shown to increase exposure of melanin subunits, while stronger photodegradation caused a loss of mela …70Cite 

Signaling by hydrogen sulfide and cyanide through post-translational modification.

Gotor C, García I, Aroca Á, Laureano-Marín AM, Arenas-Alfonseca L, Jurado-Flores A, Moreno I, Romero LC.J Exp Bot. 2019 Aug 19;70(16):4251-4265. doi: 10.1093/jxb/erz225.PMID: 31087094 Review.

The mode of action of cyanide is under investigation, although it has recently been demonstrated to perform post-translational modification of protein cysteine thiols to form thiocyanate, a process called S-cyanylation. Therefore, the signaling roles of sulfide and most pr …71Cite 

Lindera glauca (Siebold et Zucc.) Blume Stem Extracts Protect Against tert-Butyl Hydroperoxide-Induced Oxidative Stress.

Kim YS, Kim EK, Dong X, Park JS, Shin WB, Kim SJ, Go EA, Park PJ, Lim BO.J Med Food. 2019 May;22(5):508-520. doi: 10.1089/jmf.2018.4289.PMID: 31084540

Lipid peroxidation was estimated using ferric thiocyanate (FTC) and thiobarbituric acid (TBA) method. Both LGSW and LGSE strongly inhibited lipid peroxidation. …72Cite 

Thiocyanate-induced labilization of schwertmannite: Impacts and mechanisms.

Fan C, Guo C, Zhang J, Ding C, Li X, Reinfelder JR, Lu G, Shi Z, Dang Z.J Environ Sci (China). 2019 Jun;80:218-228. doi: 10.1016/j.jes.2018.12.015. Epub 2018 Dec 29.PMID: 30952339

Understanding the mechanisms that induce schwertmannite labilization and affect its capacity to remove heavy metals are of great environmental and geochemical significance. Thiocyanate (SCN) is a hazardous pseudohalide that is also normally found in AMD. However, little is …73Cite 

A halogen-bonding foldamer molecular film for selective reagentless anion sensing in water.

Hein R , Borissov A , Smith MD , Beer PD , Davis JJ .Chem Commun (Camb). 2019 Apr 18;55(33):4849-4852. doi: 10.1039/c9cc00335e.PMID: 30950463

We describe self-assembled monolayers of novel halogen-bonding and hydrogen-bonding foldamer receptors capable of selectively recruiting perrhenate, iodide and thiocyanate in water. Unprecedented anion sensing via impedance-derived capacitance spectroscopy enables subseque …74Cite 

The Significance of Lactoperoxidase System in Oral Health: Application and Efficacy in Oral Hygiene Products.

Magacz M, Kędziora K, Sapa J, Krzyściak W.Int J Mol Sci. 2019 Mar 21;20(6):1443. doi: 10.3390/ijms20061443.PMID: 30901933 Free PMC article. Review.

The main role of this enzyme is to oxidize salivary thiocyanate ions (SCN(-)) in the presence of hydrogen peroxide (H2O2) to products that exhibit antimicrobial activity. …75Cite 

Metal-based biologically active compounds: Synthesis, spectral and antioxidant studies of transition metal complexes with hydrazone derivatives.

Tanoli AK, Khan Z, Kamal T, Ali M, Latif M, Maqsood ZT.Pak J Pharm Sci. 2019 Jan;32(1):103-108.PMID: 3077279776Cite 

Removal of cyanide adsorbed on pyrite by H₂O₂ oxidation under alkaline conditions.

Tu Y, Han P, Wei L, Zhang X, Yu B, Qian P, Ye S.J Environ Sci (China). 2019 Apr;78:287-292. doi: 10.1016/j.jes.2018.10.013. Epub 2018 Nov 14.PMID: 30665647

The removal of cyanide adsorbed on pyrite by H(2)O(2) oxidation under alkaline conditions was due to the oxidation of pyrite. Hexacyanoferrate, thiocyanate and sulfate were generated with mole ratios of about 2.03:1.12:3.17 during the cyanide removal….77Cite 

Degradation of cyanide, aniline and phenol in pre-treated coke oven wastewater by peroxide assisted electro-oxidation process.

Singh H, Mishra BK.Water Sci Technol. 2018 Dec;78(10):2214-2227. doi: 10.2166/wst.2018.503.PMID: 30629549

The present study explored the feasibility of using graphite electrodes for the electrochemical oxidation of cyanide, thiocyanate, phenol and aniline with hydrogen peroxide. The dosing effects of hydrogen peroxide and current density were examined in the pre-treated coke o …78Cite 

Methylseleninic Acid Induces Lipid Peroxidation and Radiation Sensitivity in Head and Neck Cancer Cells.

Lafin JT, Sarsour EH, Kalen AL, Wagner BA, Buettner GR, Goswami PC.Int J Mol Sci. 2019 Jan 8;20(1):225. doi: 10.3390/ijms20010225.PMID: 30626124 Free PMC article.

Results from 4,4-difluoro-4-bora-3a,4a-diaza-S-indacene (BODIPY) C11 oxidation and ferric thiocyanate assays revealed that MSA induced LPO in cells rapidly and persistently. Propidium iodide (PI) exclusion assay found that MSA was more toxic to cancer cells than other rela …79Cite 

Application of metabolic division of labor in simultaneous removal of nitrogen and thiocyanate from wastewater.

Pan J, Ma J, Wu H, Chen B, He M, Liao C, Wei C.Water Res. 2019 Mar 1;150:216-224. doi: 10.1016/j.watres.2018.11.070. Epub 2018 Nov 30.PMID: 30528918

Here, we present a combined experimental and modeling study on the simultaneous removal of nitrogen and thiocyanate from wastewater by using a syntrophic microbial community. The syntrophic division of labor was achieved by coupling autotrophic denitrification (AD) and ana …80Cite 

Functional Annotation and Analysis of Dual Oxidase 1 (DUOX1): a Potential Anti-pyocyanin Immune Component.

Rashid MI, Ali A, Andleeb S.Interdiscip Sci. 2019 Dec;11(4):597-610. doi: 10.1007/s12539-018-0308-1. Epub 2018 Nov 27.PMID: 30483939

Upon detection of bacterial pathogens mainly Pseudomonas aeruginosa, DUOX1 is activated in bronchial epithelial cells. Both the host and pathogen enter a redox dual with DUOX1 and hypothiocyanite from host and Pyocyanin (PCN) as a redox active virulence factor from …81Cite 

Low-level thiocyanate concentrations impact on iron oxidation activity and growth of Leptospirillum ferriphilum through inhibition and adaptation.

Edward CJ, Kotsiopoulos A, Harrison STL.Res Microbiol. 2018 Dec;169(10):576-581. doi: 10.1016/j.resmic.2018.10.003. Epub 2018 Nov 2.PMID: 30391481 Free article.

Ferrous iron oxidation activity and growth of unadapted and thiocyanate-adapted L. ferriphilum HT was studied in batch culture across increasing thiocyanate (SCN(-)) concentrations in the range 0-2 mg/L to assess the feasibility of recycling remediated cyanidation w …82Cite 

Ag/Pyridine Co-Mediated Oxidative Arylthiocyanation of Activated Alkenes.

Kong DL, Du JX, Chu WM, Ma CY, Tao JY, Feng WH.Molecules. 2018 Oct 22;23(10):2727. doi: 10.3390/molecules23102727.PMID: 30360416 Free PMC article.

These mechanistic results may impact the design and refinement of other radical based reactions proceeding through catalytic oxidations mediated by Ag(I)-pyridine/persulfate. The chemical versatility of thiocyanate moiety was also highlighted via SCN-tailoring chemistry in …83Cite 

Ruthenium pyridyl thiocyanate complex increased the production of pro-inflammatory TNFalpha and IL1beta cytokines by the LPS stimulated mammalian macrophages in vitro.

Ayaz F.Mol Biol Rep. 2018 Dec;45(6):2307-2312. doi: 10.1007/s11033-018-4392-4. Epub 2018 Oct 4.PMID: 30284682

In our study we used a ruthenium pyridyl thiocyanate complex, K330, to examine its effect on the activity of the innate immune system cells, macrophages in vitro. …84Cite 

Synergistic inhibition of anaerobic ammonium oxidation (anammox) activity by phenol and thiocyanate.

Oshiki M, Masuda Y, Yamaguchi T, Araki N.Chemosphere. 2018 Dec;213:498-506. doi: 10.1016/j.chemosphere.2018.09.055. Epub 2018 Sep 10.PMID: 30245226

Coke-oven wastewater discharged from the steel-manufacturing process is phenol and thiocyanate (SCN)-rich wastewater, which inhibits microbial activities in biological wastewater treatment processes. …85Cite 

Determination of thiocyanate in exhaled breath condensate.

Chandler JD, Horati H, Walker DI, Pagliano E, Tirouvanziam R, Veltman M, Scholte BJ, Janssens HM, Go YM, Jones DP.Free Radic Biol Med. 2018 Oct;126:334-340. doi: 10.1016/j.freeradbiomed.2018.08.012. Epub 2018 Aug 22.PMID: 30144632 Free PMC article.

Thiocyanate is a heme peroxidase substrate that scavenges oxidants produced during inflammation and regulates host defense. …The method reliably quantified as little as 4 pmol thiocyanate in EBC and could detect even lower amounts. We successfully measured thio …86Cite 

Monitoring Dose Response of Cyanide Antidote Dimethyl Trisulfide in Rabbits Using Diffuse Optical Spectroscopy.

Lee J, Rockwood G, Logue B, Manandhar E, Petrikovics I, Han C, Bebarta V, Mahon SB, Burney T, Brenner M.J Med Toxicol. 2018 Dec;14(4):295-305. doi: 10.1007/s13181-018-0680-6. Epub 2018 Aug 9.PMID: 30094773 Free PMC article.

Dimethyl trisulfide (DMTS) is capable of reacting with CN to form the less toxic thiocyanate with high efficiency, even without the sulfurtransferase rhodanese. We investigated a soluble DMTS formulation with the potential to provide a continuous supply of substrate for CN …87Cite 

Redox Interconversion between Cobalt(III) Thiolate and Cobalt(II) Disulfide Compounds.

Jiang F, Siegler MA, Sun X, Jiang L, Fonseca Guerra C, Bouwman E.Inorg Chem. 2018 Aug 6;57(15):8796-8805. doi: 10.1021/acs.inorgchem.8b00549. Epub 2018 Jul 19.PMID: 30024150 Free PMC article.

The redox interconversion between Co(III) thiolate and Co(II) disulfide compounds has been investigated experimentally and computationally. …This work is an unprecedented example of redox interconversion between a high-spin Co(II) disulfide compound and a low-spin …88Cite 

Konzo: a distinct neurological disease associated with food (cassava) cyanogenic poisoning.

Kashala-Abotnes E, Okitundu D, Mumba D, Boivin MJ, Tylleskär T, Tshala-Katumbay D.Brain Res Bull. 2019 Feb;145:87-91. doi: 10.1016/j.brainresbull.2018.07.001. Epub 2018 Jul 5.PMID: 29981837 Free PMC article. Review.

Biochemical and toxicological studies suggest that the metabolites of linamarin (alpha-Hydroxyisobutyronitrile beta-D-glucopyranoside, the main cassava cyanogen), notably cyanide (mitochondrial toxin), thiocyanate (AMPA chaotropic agent), and cyanate (protein carbamoylatin …89Cite 

Can the Electron-Accepting Properties of Odorants Be Involved in Their Recognition by the Olfactory System?

Pshenichnyuk SA, Rakhmeyev RG, Asfandiarov NL, Komolov AS, Modelli A, Jones D.J Phys Chem Lett. 2018 May 3;9(9):2320-2325. doi: 10.1021/acs.jpclett.8b00704. Epub 2018 Apr 23.PMID: 2966567990Cite 

Cigarette smoke modifies neutrophil chemotaxis, neutrophil extracellular trap formation and inflammatory response-related gene expression.

White PC, Hirschfeld J, Milward MR, Cooper PR, Wright HJ, Matthews JB, Chapple ILC.J Periodontal Res. 2018 Aug;53(4):525-535. doi: 10.1111/jre.12542. Epub 2018 Mar 25.PMID: 29574730

This study tested the hypothesis that cigarette smoke extract (CSE) and its components/metabolites nicotine, cotinine and thiocyanate (SCN-), may influence neutrophil functions. MATERIAL AND METHODS: Chemotaxis was assessed in neutrophils pre-treated with CSE using real-ti …91Cite 

Myeloperoxidase-catalyzed oxidation of cyanide to cyanate: A potential carbamylation route involved in the formation of atherosclerotic plaques?

Delporte C, Zouaoui Boudjeltia K, Furtmüller PG, Maki RA, Dieu M, Noyon C, Soudi M, Dufour D, Coremans C, Nuyens V, Reye F, Rousseau A, Raes M, Moguilevsky N, Vanhaeverbeek M, Ducobu J, Nève J, Robaye B, Vanhamme L, Reynolds WF, Obinger C, Van Antwerpen P.J Biol Chem. 2018 Apr 27;293(17):6374-6386. doi: 10.1074/jbc.M117.801076. Epub 2018 Mar 1.PMID: 29496995 Free PMC article.

Moreover, we present two further pathways of carbamylation that involve reaction products of MPO, namely oxidation of cyanide by hypochlorous acid and reaction of thiocyanate with chloramines. Finally, using an in vivo approach with mice on a high-fat diet and carrying the …92Cite 

Pulsed corona discharge for improving treatability of coking wastewater.

Liu M, Preis S, Kornev I, Hu Y, Wei CH.J Environ Sci (China). 2018 Feb;64:306-316. doi: 10.1016/j.jes.2017.07.003. Epub 2017 Jul 12.PMID: 29478652

The energy efficiency of COD, phenol, thiocyanate and cyanide degradation by PCD was the subject of the research. The cost-effective removal of intermediate oxidation products with addition of lime was also studied. …Oxidative treatment of RCW showed the removal of pheno …93Cite 

Comparison of Adaptive Neuroprotective Mechanisms of Sulforaphane and its Interconversion Product Erucin in in Vitro and in Vivo Models of Parkinson’s Disease.

Morroni F, Sita G, Djemil A, D’Amico M, Pruccoli L, Cantelli-Forti G, Hrelia P, Tarozzi A.J Agric Food Chem. 2018 Jan 31;66(4):856-865. doi: 10.1021/acs.jafc.7b04641. Epub 2018 Jan 22.PMID: 2930717994Cite 

Simultaneous nitrite and ammonium production in an autotrophic partial denitrification and ammonification of wastewaters containing thiocyanate.

Pan J, Wei C, Fu B, Ma J, Preis S, Wu H, Zhu S.Bioresour Technol. 2018 Mar;252:20-27. doi: 10.1016/j.biortech.2017.12.059. Epub 2017 Dec 20.PMID: 29306125

The study aimed to develop a novel denitrification process forming nitrite and ammonium in wastewaters containing thiocyanate. High-efficiency nitrite and ammonium production was observed due to autotrophic partial denitrification and ammonification as a result of nitrate …95Cite 

Kinetics of Decomposition of Thiocyanate in Natural Aquatic Systems.

Kurashova I, Halevy I, Kamyshny A Jr.Environ Sci Technol. 2018 Feb 6;52(3):1234-1243. doi: 10.1021/acs.est.7b04723. Epub 2018 Jan 18.PMID: 29283564

Rates of thiocyanate degradation were measured in waters and sediments of marine and limnic systems under various redox conditions, oxic, anoxic (nonsulfidic, nonferruginous, nonmanganous), ferruginous, sulfidic, and manganous, for up to 200-day period at micromolar …96Cite 

Reaction Product Variability and Biological Activity of the Lactoperoxidase System Depending on Medium Ionic Strength and pH, and on Substrate Relative Concentration.

Bafort F, Damblon C, Smargiasso N, De Pauw E, Perraudin JP, Jijakli MH.Chem Biodivers. 2018 Mar;15(3):e1700497. doi: 10.1002/cbdv.201700497. Epub 2018 Mar 7.PMID: 2926674197Cite 

Secreted heme peroxidase from Dictyostelium discoideum: Insights into catalysis, structure, and biological role.

Nicolussi A, Dunn JD, Mlynek G, Bellei M, Zamocky M, Battistuzzi G, Djinović-Carugo K, Furtmüller PG, Soldati T, Obinger C.J Biol Chem. 2018 Jan 26;293(4):1330-1345. doi: 10.1074/jbc.RA117.000463. Epub 2017 Dec 14.PMID: 29242189 Free PMC article.

Oxidation of halides and thiocyanate by heme peroxidases to antimicrobial oxidants is an important cornerstone in the innate immune system of mammals. …The metalloprotein follows the halogenation cycle, whereby compound I oxidizes iodide and thiocyanate at high ra …98Cite 

Cyanate improves insulin sensitivity and hepatic steatosis in normal and high fat-fed mice: Anorexic and antioxidative effects.

Kang SS, Mun KC, Seo JH, Choe M, Ha E.Chem Biol Interact. 2018 Jan 5;279:121-128. doi: 10.1016/j.cbi.2017.10.026. Epub 2017 Nov 4.PMID: 29113807

Cyanate, known as uremic toxin, is an electrophile produced spontaneously from urea or by myeloperoxidase-catalyzed oxidation of thiocyanate. Herein, we explored metabolic effects of cyanate in normal chow diet (NCD)- and high fat diet (HFD)-fed mice. …99Cite 

Potentiation of antimicrobial photodynamic inactivation by inorganic salts.

Hamblin MR.Expert Rev Anti Infect Ther. 2017 Nov;15(11):1059-1069. doi: 10.1080/14787210.2017.1397512. Epub 2017 Oct 31.PMID: 29084463 Free PMC article. Review.

The most powerful and versatile salt is potassium iodide, but potassium bromide, sodium thiocyanate, sodium azide and sodium nitrite also show potentiation. The mechanism of potentiation with iodide is likely to be singlet oxygen addition to iodide to form iodine radicals, …100Cite 

Reactivation of peroxidase activity in human saliva samples by polyphenols.

Gau J, Arnhold J, Flemmig J.Arch Oral Biol. 2018 Jan;85:70-78. doi: 10.1016/j.archoralbio.2017.09.037. Epub 2017 Oct 7.PMID: 29032047

OBJECTIVES: The enzyme lactoperoxidase (LPO), which is released into several body fluids like saliva, is an essential part to maintain the oral bacterial homeostasis by catalysing the oxidation of thiocyanate (SCN(-)) to hypo-thiocyanite ((-)OSCN). The formation of unreact …101Cite 

Inhibition of 5α-Reductase, IL-6 Secretion, and Oxidation Process of Equisetum debile Roxb. ex Vaucher Extract as Functional Food and Nutraceuticals Ingredients.

Chaiyana W, Punyoyai C, Somwongin S, Leelapornpisid P, Ingkaninan K, Waranuch N, Srivilai J, Thitipramote N, Wisuitiprot W, Schuster R, Viernstein H, Mueller M.Nutrients. 2017 Oct 10;9(10):1105. doi: 10.3390/nu9101105.PMID: 28994714 Free PMC article.

The inhibition of lipid peroxidation was determined by the ferric thiocyanate method. The cytotoxicity of the extracts on dermal papilla cells and irritation test by hen’s egg test chorioallantoic membrane assay were also investigated. …102Cite 

A single-domain rhodanese homologue MnRDH1 helps to maintain redox balance in Macrobrachium nipponense.

Tang T, Li X, Liu X, Wang Y, Ji C, Wang Y, Wang X, Xie S, Liu F, Wang J.Dev Comp Immunol. 2018 Jan;78:160-168. doi: 10.1016/j.dci.2017.09.022. Epub 2017 Oct 4.PMID: 28987482

Rhodaneses are known to catalyze in vitro the transfer of a sulfane sulfur atom from thiosulfate to cyanide with concomitant formation of thiocyanate, however, their biological functions remain speculative despite the main role is considered as detoxifying cyanide especial …103Cite 

Effect of heat shock protein 90 against ROS-induced phospholipid oxidation.

Zhang M, Wang D, Geng Z, Li P, Sun Z, Xu W.Food Chem. 2018 Feb 1;240:642-647. doi: 10.1016/j.foodchem.2017.08.005. Epub 2017 Aug 2.PMID: 28946323

Lipid oxidation was assessed by ferric thiocyanate method, and particle size, zeta potential measurements and transmission electron microscopy were employed to detect physical and chemical changes during oxidation of liposomes. …104Cite 

Antioxidant Activity of Extract from the Cephalothorax of Fenneropenaeus chinensis.

Kim YS, Kim EK, Ryu BI, Jeon NJ, Hwang JW, Choi EJ, Moon SH, Jeon BT, Park PJ.Adv Exp Med Biol. 2017;975 Pt 2:1153-1163. doi: 10.1007/978-94-024-1079-2_92.PMID: 28849530

The lipid peroxidation was estimated using ferric thiocyanate (FTC) assay and thiobarbituric acid (TBA) methods. However, a higher lipid peroxidation activity was observed in TBA method than FTC method. …105Cite 

Low-density lipoprotein modified by myeloperoxidase oxidants induces endothelial dysfunction.

Abdo AI, Rayner BS, van Reyk DM, Hawkins CL.Redox Biol. 2017 Oct;13:623-632. doi: 10.1016/j.redox.2017.08.004. Epub 2017 Aug 5.PMID: 28818791 Free PMC article.

Low-density lipoprotein (LDL) modified by hypochlorous acid (HOCl) produced by myeloperoxidase (MPO) is present in atherosclerotic lesions, where it is implicated in the propagation of inflammation and acceleration of lesion development by multiple pathways, including the inducti …106Cite 

Reaction of Dimethyl Trisulfide with Hemoglobin.

Dong X, Kiss L, Petrikovics I, Thompson DE.Chem Res Toxicol. 2017 Sep 18;30(9):1661-1663. doi: 10.1021/acs.chemrestox.7b00181. Epub 2017 Aug 18.PMID: 28809548

DMTS acts as a sulfur donor in the conversion of cyanide to the less-toxic thiocyanate. The alternate reaction pathways of DMTS in the blood are not well understood. …107Cite 

Determination of Enzymes Associated with Sulfite Toxicity in Plants: Kinetic Assays for SO, APR, SiR, and In-Gel SiR Activity.

Brychkova G, Kurmanbayeva A, Bekturova A, Khozin I, Standing D, Yarmolinsky D, Sagi M.Methods Mol Biol. 2017;1631:229-251. doi: 10.1007/978-1-4939-7136-7_14.PMID: 28735401

Additionally, cysteine serves as a precursor for the biosynthesis of glutathione, the reactive oxygen species scavenger essential for redox status homeostasis during stress. Cysteine is generated by the sulfate reductive pathway where sulfite oxidase (SO; EC 1.8.3.1) is an …108Cite 

Possible Reactions of Dietary Phenolic Compounds with Salivary Nitrite and Thiocyanate in the Stomach.

Takahama U, Hirota S.Antioxidants (Basel). 2017 Jul 5;6(3):53. doi: 10.3390/antiox6030053.PMID: 28678174 Free PMC article. Review.

Because a salivary component of nitrite is protonated to produce active nitrous acid at acidic pH, the redox reactions of nitrous acid with phenolic compounds in foods become possible in the stomach. …Caffeic acid, chlorogenic acid, and rutin are oxidized to quinones and …109Cite 

In vitro and in vivo antioxidative and hepatoprotective activity of aqueous extract of Cortex Dictamni.

Li L, Zhou YF, Li YL, Wang LL, Arai H, Xu Y.World J Gastroenterol. 2017 Apr 28;23(16):2912-2927. doi: 10.3748/wjg.v23.i16.2912.PMID: 28522909 Free PMC article.

A linoleic acid system, including ferric thiocyanate (FTC) and thiobarbituric acid (TBA) assays, was used to evaluate the inhibition of lipid peroxidation. …110Cite 

Iodine-Pseudohalogen Ionic Liquid-Based Electrolytes for Quasi-Solid-State Dye-Sensitized Solar Cells.

Lennert A, Sternberg M, Meyer K, Costa RD, Guldi DM.ACS Appl Mater Interfaces. 2017 Oct 4;9(39):33437-33445. doi: 10.1021/acsami.7b01522. Epub 2017 Apr 27.PMID: 28448122

The latter were mixed with additives such as 4-tert-butylpyridine (4tbpy) and guanidinium thiocyanate (GuSCN) to optimize electrode surface coverage, ionic diffusion, and dye regeneration. …111Cite 

Tannins and Tannin-Related Derivatives Enhance the (Pseudo-)Halogenating Activity of Lactoperoxidase.

Gau J, Prévost M, Van Antwerpen P, Sarosi MB, Rodewald S, Arnhold J, Flemmig J.J Nat Prod. 2017 May 26;80(5):1328-1338. doi: 10.1021/acs.jnatprod.6b00915. Epub 2017 Apr 3.PMID: 28368593112Cite 

Thiocyanates as attractive redox-active electrolytes for high-energy and environmentally-friendly electrochemical capacitors.

Gorska B, Bujewska P, Fic K.Phys Chem Chem Phys. 2017 Mar 15;19(11):7923-7935. doi: 10.1039/c7cp00722a.PMID: 28262879

Therefore, thiocyanate-based electrolytes were recognized as cheap and highly conductive electrolytic solutions (up to 401 mS cm(-1) for NH(4)SCN at RT) allowing a cell voltage of 1.6 V in a symmetric carbon/carbon system to be achieved. At the same time, they display an a …113Cite 

Pre-steady-state Kinetics Reveal the Substrate Specificity and Mechanism of Halide Oxidation of Truncated Human Peroxidasin 1.

Paumann-Page M, Katz RS, Bellei M, Schwartz I, Edenhofer E, Sevcnikar B, Soudi M, Hofbauer S, Battistuzzi G, Furtmüller PG, Obinger C.J Biol Chem. 2017 Mar 17;292(11):4583-4592. doi: 10.1074/jbc.M117.775213. Epub 2017 Jan 31.PMID: 28154175 Free PMC article.

The heme enzyme is shown to follow the halogenation cycle that is induced by the rapid H(2)O(2)-mediated oxidation of the ferric enzyme to the redox intermediate compound I. We demonstrate that chloride cannot act as a two-electron donor of compound I, whereas thiocyana …114Cite 

ZnO Nanostructures for Dye-Sensitized Solar Cells Using the TEMPO(+) /TEMPO Redox Mediator and Ruthenium(II) Photosensitizers with 1,2,3-Triazole-Derived Ligands.

Wahyuono RA, Schulze B, Rusu M, Wächtler M, Dellith J, Seyring M, Rettenmayr M, Plentz J, Ignaszak A, Schubert US, Dietzek B.Chempluschem. 2016 Dec;81(12):1281-1291. doi: 10.1002/cplu.201600377. Epub 2016 Sep 20.PMID: 31964059

A series of thiocyanate-free bis(tridentate) ruthenium(II) complexes incorporating 1,2,3-triazole-derived NNN-, NCN-, and CNC-coordinating ligands has been employed for sensitizing ZnO photoanodes for dye-sensitized solar cells (DSSCs). Additionally, the first use of the T …115Cite 

A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.

Johnson GS, Li J, Beaver LM, Dashwood WM, Sun D, Rajendran P, Williams DE, Ho E, Dashwood RH.Mol Nutr Food Res. 2017 Apr;61(4):10.1002/mnfr.201600769. doi: 10.1002/mnfr.201600769. Epub 2017 Jan 3.PMID: 27860235 Free PMC article.

This noncoding RNA was confirmed as a novel functional pseudogene for NmrA-like redox sensor 1, and was given the name NmrA-like redox sensor 2 pseudogene (NMRAL2P). …116Cite 

Effects of thiocyanate on granule-based anammox process and implications for regulation.

Chen QQ, Chen H, Zhang ZZ, Guo LX, Jin RC.J Hazard Mater. 2017 Jan 5;321:81-91. doi: 10.1016/j.jhazmat.2016.08.044. Epub 2016 Aug 16.PMID: 27614321

A typical noncompetitive model was used to fit the data for thiocyanate inhibition, and the 50% inhibition concentration (IC(50)) of thiocyanate on anammox was 620.4mgL(-1) at 200mgL(-1) total nitrogen level. …The NRE was decreased to 57.1% under 130mgL(-1) thi …117Cite 

Molecularly Engineered Ru(II) Sensitizers Compatible with Cobalt(II/III) Redox Mediators for Dye-Sensitized Solar Cells.

Wu KL, Huckaba AJ, Clifford JN, Yang YW, Yella A, Palomares E, Grätzel M, Chi Y, Nazeeruddin MK.Inorg Chem. 2016 Aug 1;55(15):7388-95. doi: 10.1021/acs.inorgchem.6b00427. Epub 2016 Jul 15.PMID: 27420188

Thiocyanate-free isoquinazolylpyrazolate Ru(II) complexes were synthesized and applied as sensitizers in dye-sensitized solar cells (DSCs). …118Cite 

New insights into thiocyanate oxidation by human myeloperoxidase.

Schlorke D, Flemmig J, Gau J, Furtmüller PG, Obinger C, Arnhold J.J Inorg Biochem. 2016 Sep;162:117-126. doi: 10.1016/j.jinorgbio.2016.06.019. Epub 2016 Jun 15.PMID: 27343172

Human myeloperoxidase (MPO) uses chloride and thiocyanate as physiological substrates at neutral pH. Oxidation of thiocyanate to hypothiocyanite mediated by the redox intermediate Compound I rapidly restores the ferric state of MPO. At low thiocyanate …119Cite 

Rapid determination of lipid peroxidation using a novel pyridoxamine-participating ferrous oxidation-sulfosalicylic acid spectrophotometric method.

Chen J, Cai D, Zhang Y.Food Chem. 2016 Nov 15;211:637-44. doi: 10.1016/j.foodchem.2016.05.106. Epub 2016 May 17.PMID: 27283678

In addition, current method has a significant linear correlation with both conventional thiobarbituric acid (R(2)=0.9999) and ferric thiocyanate assays (R(2)=0.9675). This method offers a rapid technique for evaluating lipid peroxidation without heating and sophisticated i …120Cite 

Nitrite and nitroso compounds can serve as specific catalase inhibitors.

Titov VY, Osipov AN.Redox Rep. 2017 Mar;22(2):91-97. doi: 10.1080/13510002.2016.1168589. Epub 2016 Apr 14.PMID: 27075937 Free PMC article.

It was found that chloride and bromide in concentration above 80 mM and thiocyanate in concentration above 20 muM enhance catalase inhibition by nitrite and the nitroso compounds more than 100 times. …This group acquires a positive charge in the active center of enzyme b …121Cite 

Reactive Oxygen Species and Neutrophil Function.

Winterbourn CC, Kettle AJ, Hampton MB.Annu Rev Biochem. 2016 Jun 2;85:765-92. doi: 10.1146/annurev-biochem-060815-014442. Epub 2016 Apr 6.PMID: 27050287 Review.122Cite 

Measurement of Antioxidant Capacity by Electron Spin Resonance Spectroscopy Based on Copper(II) Reduction.

Li D, Jiang J, Han D, Yu X, Wang K, Zang S, Lu D, Yu A, Zhang Z.Anal Chem. 2016 Apr 5;88(7):3885-90. doi: 10.1021/acs.analchem.6b00049. Epub 2016 Mar 9.PMID: 26927869123Cite 

High photo-currents with a zwitterionic thiocyanate-free dye in aqueous-based dye sensitized solar cells.

Fayad R, Shoker TA, Ghaddar TH.Dalton Trans. 2016 Apr 7;45(13):5622-8. doi: 10.1039/c6dt00071a. Epub 2016 Feb 29.PMID: 26924085

We report a new water soluble and stable thiolate/disulfide redox couple (T(-)/DS) and its use with a new zwitterionic and thiocyanate-free dye (T169) in a 100% aqueous electrolyte system. …124Cite 

Antioxidant and ACE Inhibitory Bioactive Peptides Purified from Egg Yolk Proteins.

Yousr M, Howell N.Int J Mol Sci. 2015 Dec 7;16(12):29161-78. doi: 10.3390/ijms161226155.PMID: 26690134 Free PMC article.125Cite 

The myeloperoxidase-derived oxidant hypothiocyanous acid inhibits protein tyrosine phosphatases via oxidation of key cysteine residues.

Cook NL, Moeke CH, Fantoni LI, Pattison DI, Davies MJ.Free Radic Biol Med. 2016 Jan;90:195-205. doi: 10.1016/j.freeradbiomed.2015.11.025. Epub 2015 Nov 23.PMID: 26616646

Phosphorylation of protein tyrosine residues is critical to cellular processes, and is regulated by kinases and phosphatases (PTPs). PTPs contain a redox-sensitive active site Cys residue, which is readily oxidized. Myeloperoxidase, released from activated leukocytes, cata …126Cite 

Formation of cyanogen iodide by lactoperoxidase.

Schlorke D, Flemmig J, Birkemeyer C, Arnhold J.J Inorg Biochem. 2016 Jan;154:35-41. doi: 10.1016/j.jinorgbio.2015.11.005. Epub 2015 Nov 3.PMID: 26580225

Here we describe the formation of the inter(pseudo)halogen cyanogen iodide (ICN) by LPO. This product is formed when both, thiocyanate and iodide, are present together in the reaction mixture. Using (13)C nuclear magnetic resonance spectroscopy and gas chromatography-mass …127Cite 

Lactoperoxidase as a potential drug target.

Flemmig J, Gau J, Schlorke D, Arnhold J.Expert Opin Ther Targets. 2016;20(4):447-61. doi: 10.1517/14728222.2016.1112378. Epub 2015 Nov 11.PMID: 26558497 Review.

The enzyme contributes in external secretions to the humoral immune defense against pathogens by oxidation of thiocyanate (SCN(-)) and iodide (I(-)). The generation of oxidized thiocyanate and/or iodine species is also important in numerous biotechnological applicat …128Cite 

Purification and Characterization of a Novel Redox-Regulated Isoform of Myrosinase (beta-Thioglucoside Glucohydrolase) from Lepidium latifolium L.

Bhat R, Kaur T, Khajuria M, Vyas R, Vyas D.J Agric Food Chem. 2015 Dec 2;63(47):10218-26. doi: 10.1021/acs.jafc.5b04468. Epub 2015 Nov 19.PMID: 26527478

With sinigrin as substrate, the enzyme showed Km and Vmax values of 171 23 muM and 0.302 mumol min(-1) mg(-1), respectively. The enzyme was found to be redox-regulated, with an increase in Vmax and Kcat in the presence of GSH. Reduced forms of the enzyme were found to be m …129Cite 

Photoinduced Bimolecular Electron Transfer from Cyano Anions in Ionic Liquids.

Wu B, Liang M, Maroncelli M, Castner EW Jr.J Phys Chem B. 2015 Nov 19;119(46):14790-9. doi: 10.1021/acs.jpcb.5b09216. Epub 2015 Nov 9.PMID: 26501776

The set of five cyano anion ILs studied comprises the 1-ethyl-3-methylimidazolium cation paired with each of these five anions: selenocyanate, thiocyanate, dicyanamide, tricyanomethanide, and tetracyanoborate. Measurements with these anions dilute in acetonitrile and 1-eth …130Cite 

Formation of stable radicals in catechin/nitrous acid systems: participation of dinitrosocatechin.

Morina F, Takahama U, Mojović M, Popović-Bijelić A, Veljović-Jovanović S.Food Chem. 2016 Mar 1;194:1116-22. doi: 10.1016/j.foodchem.2015.08.081. Epub 2015 Aug 21.PMID: 26471661131Cite 

Micro Ion Extractor for Single Drop Whole Blood Analysis.

Nakamura Y, Maeda S, Nishiyama H, Ohira S, Dasgupta PK, Toda K.Anal Chem. 2015 Jul 7;87(13):6483-6. doi: 10.1021/acs.analchem.5b01681. Epub 2015 Jun 22.PMID: 26084326

A reproducible fraction of iodide and thiocyanate was transferred through a membrane to an acceptor solution layer by electromigration for 60 s. An isolator solution layer and a cation exchange membrane is provided between the acceptor and the anode to prevent gas formatio …132Cite 

Bioreactor microbial ecosystems for thiocyanate and cyanide degradation unravelled with genome-resolved metagenomics.

Kantor RS, van Zyl AW, van Hille RP, Thomas BC, Harrison ST, Banfield JF.Environ Microbiol. 2015 Dec;17(12):4929-41. doi: 10.1111/1462-2920.12936. Epub 2015 Jul 28.PMID: 26031303 Free article.

Gold ore processing uses cyanide (CN(-) ), which often results in large volumes of thiocyanate– (SCN(-) ) contaminated wastewater requiring treatment. Microbial communities can degrade SCN(-) and CN(-) , but little is known about their membership and metabolic potential. . …133Cite 

Comparison of five analytical methods for the determination of peroxide value in oxidized ghee.

Mehta BM, Darji VB, Aparnathi KD.Food Chem. 2015 Oct 15;185:449-53. doi: 10.1016/j.foodchem.2015.04.023. Epub 2015 Apr 14.PMID: 25952892

Bureau of Indian Standard (BIS), Association of Analytical Communities (AOAC) and American Oil Chemists’ Society (AOCS), and two colorimetric methods, the ferrous xylenol orange (FOX) and ferric thiocyanate (International Dairy Federation, IDF) methods based on oxidation o …134Cite 

Preparation and X-ray Structural Study of Dibenziodolium Derivatives.

Postnikov PS, Guselnikova OA, Yusubov MS, Yoshimura A, Nemykin VN, Zhdankin VV.J Org Chem. 2015 Jun 5;80(11):5783-8. doi: 10.1021/acs.joc.5b00741. Epub 2015 May 15.PMID: 25951091

Dibenziodolium hydrogen sulfate, bis(triflyl)imidate, or triflate can be readily converted to various other dibenziodolium derivatives (chloride, bromide, thiocyanate, azide, cyanide, phenylsulfinate) by anion exchange. Structures of key products have been established by s …135Cite 

Comparative reactivity of the myeloperoxidase-derived oxidants HOCl and HOSCN with low-density lipoprotein (LDL): Implications for foam cell formation in atherosclerosis.

Ismael FO, Proudfoot JM, Brown BE, van Reyk DM, Croft KD, Davies MJ, Hawkins CL.Arch Biochem Biophys. 2015 May 1;573:40-51. doi: 10.1016/j.abb.2015.03.008. Epub 2015 Mar 18.PMID: 25795019

However, the reactivity of the other major MPO oxidant, hypothiocyanous acid (HOSCN) with LDL is poorly characterised, which is significant given that thiocyanate is the favoured substrate for MPO. In this study, we comprehensively compare the reactivity of HOCl and HOSCN …136Cite 

Real-time assays for monitoring the influence of sulfide and sulfane sulfur species on protein thiol redox states.

Greiner R, Dick TP.Methods Enzymol. 2015;555:57-77. doi: 10.1016/bs.mie.2014.11.020. Epub 2015 Jan 10.PMID: 25747475

Here, we detail in vitro assays for the real-time monitoring of thiol redox states in two model proteins with oxidizable cysteines, PTEN, and roGFP2. These allow kinetic measurements of the response of defined protein thiols (or disulfides) to sulfide and sulfane sulfur sp …137Cite 

Possible roles of plant sulfurtransferases in detoxification of cyanide, reactive oxygen species, selected heavy metals and arsenate.

Most P, Papenbrock J.Molecules. 2015 Jan 14;20(1):1410-23. doi: 10.3390/molecules20011410.PMID: 25594348 Free PMC article. Review.

Maintenance of the GSH/GSSG ratio is important for cellular redox balance, which is crucial for the survival of the plants. In this context, sulfurtransferases (Str), also called rhodaneses, comprise a group of enzymes widely distributed in all phyla, paving the way for th …138Cite 

Biochemical mechanisms and therapeutic potential of pseudohalide thiocyanate in human health.

Chandler JD, Day BJ.Free Radic Res. 2015 Jun;49(6):695-710. doi: 10.3109/10715762.2014.1003372. Epub 2015 Jan 28.PMID: 25564094 Free PMC article. Review.

Thiocyanate (SCN(-)) is a ubiquitous molecule in mammalian biology, reaching up to mM concentrations in extracellular fluids. …139Cite 

A mild copper-catalyzed aerobic oxidative thiocyanation of arylboronic acids with TMSNCS.

Sun N, Che L, Mo W, Hu B, Shen Z, Hu X.Org Biomol Chem. 2015 Jan 21;13(3):691-6. doi: 10.1039/c4ob02208d.PMID: 25514847

A facile and efficient transformation of arylboronic acids to their corresponding aryl thiocyanates has been successfully developed. Based on the CuCl-catalyzed oxidative cross-coupling reaction between arylboronic acids and trimethylsilylisothiocyanate (TMSNCS) under oxyg …140Cite 

Antiinflammatory and Antimicrobial Effects of Thiocyanate in a Cystic Fibrosis Mouse Model.

Chandler JD, Min E, Huang J, McElroy CS, Dickerhof N, Mocatta T, Fletcher AA, Evans CM, Liang L, Patel M, Kettle AJ, Nichols DP, Day BJ.Am J Respir Cell Mol Biol. 2015 Aug;53(2):193-205. doi: 10.1165/rcmb.2014-0208OC.PMID: 25490247 Free PMC article.

Thiocyanate (SCN) is used by the innate immune system, but less is known about its impact on inflammation and oxidative stress. …SCN significantly decreased airway neutrophil infiltrate and restored the redox ratio of glutathione in lung tissue and airway epitheli …141Cite 

Enhancing the stability of porphyrin dye-sensitized solar cells by manipulation of electrolyte additives.

Lau GP, Tsao HN, Yi C, Zakeeruddin SM, Grätzel M, Dyson PJ.ChemSusChem. 2015 Jan;8(2):255-9. doi: 10.1002/cssc.201403225. Epub 2014 Dec 8.PMID: 25488713

Furthermore, we identify a previously unreported pathway for device degradation, and show that the addition of N-methylbenzimidazole and a thiocyanate salt to the electrolyte is critical to obtaining long-lived devices….142Cite 

Inactivation of human salivary glutathione transferase P1-1 by hypothiocyanite: a post-translational control system in search of a role.

Fabrini R, Bocedi A, Camerini S, Fusetti M, Ottaviani F, Passali FM, Topazio D, Iavarone F, Francia I, Castagnola M, Ricci G.PLoS One. 2014 Nov 13;9(11):e112797. doi: 10.1371/journal.pone.0112797. eCollection 2014.PMID: 25393952 Free PMC article. Clinical Trial.

Cys47 and Cys101, the most reactive sulfhydryls of GSTP1-1, are mainly involved in a redox interaction which leads to the formation of an intra-chain disulfide bridge. A reactivation procedure has been optimized and used to quantify GSTP1-1 in saliva of 30 healthy subjects …143Cite 

Effect of soybean lecithin on iron-catalyzed or chlorophyll-photosensitized oxidation of canola oil emulsion.

Choe J, Oh B, Choe E.J Food Sci. 2014 Nov;79(11):C2203-8. doi: 10.1111/1750-3841.12683. Epub 2014 Oct 13.PMID: 25312008

The effect of soybean lecithin addition on the iron-catalyzed or chlorophyll-photosensitized oxidation of emulsions consisting of purified canola oil and water (1:1, w/w) was studied based on headspace oxygen consumption using gas chromatography and hydroperoxide production using …144Cite 

Oxidative nucleophilic strategy for synthesis of thiocyanates and trifluoromethyl sulfides from thiols.

Yamaguchi K, Sakagami K, Miyamoto Y, Jin X, Mizuno N.Org Biomol Chem. 2014 Dec 7;12(45):9200-6. doi: 10.1039/c4ob01655f.PMID: 25297894

Thiocyanates and trifluoromethyl sulfides are important compounds and have classically been synthesized via multistep procedures together with the formation of significant amounts of byproducts. …OMS-2 can catalyze oxidative homocoupling of the thiolate species, thus res …145Cite 

How covalent heme to protein bonds influence the formation and reactivity of redox intermediates of a bacterial peroxidase.

Auer M, Nicolussi A, Schütz G, Furtmüller PG, Obinger C.J Biol Chem. 2014 Nov 7;289(45):31480-91. doi: 10.1074/jbc.M114.595157. Epub 2014 Sep 22.PMID: 25246525 Free PMC article.

Moreover, apparent bimolecular rate constants of the reaction of compound I with iodide, thiocyanate, bromide, and tyrosine increased significantly and became similar to LPO. Kinetic data are discussed and compared with known structure-function relationships of the mammali …146Cite 

[In vitro study of the effect of a lactoperoxidase-peroxidase-thiocyanate system with iodine on the cariogenicinity of streptococcus mutans].

Liu X, Liu Y, Liang J, Shi L, Chu J, Li B.Hua Xi Kou Qiang Yi Xue Za Zhi. 2014 Aug;32(4):404-8. doi: 10.7518/hxkq.2014.04.020.PMID: 25241547 Free PMC article. Chinese.

OBJECTIVE: This study aimed to investigate the effect of a lactoperoxidase-peroxidase-thiocyanate (LPO-H2O-SCN-) system with different concentrations of iodine (I-) on Streptococcus mutans (S. mutans), particularly on various parameters, including growth, adhesion, glucosy …147Cite 

Simultaneous oxidation of cyanide and thiocyanate at high pressure and temperature.

Oulego P, Collado S, Laca A, Díaz M.J Hazard Mater. 2014 Sep 15;280:570-8. doi: 10.1016/j.jhazmat.2014.08.051. Epub 2014 Sep 2.PMID: 25218257

Thiocyanate and cyanide are important contaminants that frequently appear mixed in industrial effluents. …The presence of cyanide (3.85 mM) increased the kinetic constant of thiocyanate degradation by a factor of 1.6, in comparison to the value obtained for the in …148Cite 

Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants.

Bonifay V, Barrett TJ, Pattison DI, Davies MJ, Hawkins CL, Ashby MT.Arch Biochem Biophys. 2014 Dec 15;564:1-11. doi: 10.1016/j.abb.2014.08.014. Epub 2014 Aug 27.PMID: 25172223

Substrate selectivity depends upon the relative abundance of the halides, but the pseudo-halide thiocyanate (SCN(-)) is a major substrate, and sometimes the exclusive substrate, of all defensive peroxidases in most physiologic fluids. …The reactant in these cases may be …149Cite 

Thiocyanate-free ruthenium(II) sensitizers for dye-sensitized solar cells based on the cobalt redox couple.

Wu KL, Clifford JN, Wang SW, Aswani Y, Palomares E, Lobello MG, Mosconi E, De Angelis F, Ku WP, Chi Y, Nazeeruddin MK, Grätzel M.ChemSusChem. 2014 Oct;7(10):2930-8. doi: 10.1002/cssc.201402030. Epub 2014 Aug 21.PMID: 25146378

Two thiocyanate-free ruthenium(II) sensitizers, TFRS-41 and TFRS-42, with distinctive dialkoxyphenyl thienyl substituents were successfully prepared and tested for potential applications in making dye-sensitized solar cells (DSCs). …In addition, DFT calculation and detai …150Cite 

Removement of thiocyanate from industrial wastewater by microwave-Fenton oxidation method.

Xi B, Shi Q.J Environ Sci (China). 2013 Dec;25 Suppl 1:S201-4. doi: 10.1016/S1001-0742(14)60656-2.PMID: 25078832

The microwave radiation oxidation process, Fenton as catalytic agent, was used to remove the thiocyanate from the industrial wastewater. The effects of microwave power, radiation time, pH and the feeding in ways of catalyst on the degradation rate of synthetic wastewater w …151Cite 

Thiocyanate complexes of uranium in multiple oxidation states: a combined structural, magnetic, spectroscopic, spectroelectrochemical, and theoretical study.

Hashem E, Platts JA, Hartl F, Lorusso G, Evangelisti M, Schulzke C, Baker RJ.Inorg Chem. 2014 Aug 18;53(16):8624-37. doi: 10.1021/ic501236j. Epub 2014 Jul 29.PMID: 25072532

Electronic absorption and photoluminescence spectra of the uranium(IV) compounds have been measured. The redox chemistry of [Et4N]4[U(NCS)8] has been explored using IR and UV-vis spectroelectrochemical methods. Reversible 1-electron oxidation of one of the coordinated t …152Cite 

High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction.

Nedoboy PE, Morgan PE, Mocatta TJ, Richards AM, Winterbourn CC, Davies MJ.Free Radic Res. 2014 Oct;48(10):1256-66. doi: 10.3109/10715762.2014.947286.PMID: 25050609

MPO uses H2O2 to generate oxidants including HOCl and HOSCN, from chloride and thiocyanate (SCN(-)) ions, respectively. SCN(-) is the preferred substrate. Elevation of this anion decreases HOCl generation and increases HOSCN formation, a thiol-specific oxidant. …153Cite 

Multiple sulfur isotopes fractionations associated with abiotic sulfur transformations in Yellowstone National Park geothermal springs.

Kamyshny A Jr, Druschel G, Mansaray ZF, Farquhar J.Geochem Trans. 2014 May 28;15:7. doi: 10.1186/1467-4866-15-7. eCollection 2014.PMID: 24959098 Free PMC article.

Triple sulfur isotope ((32)S, (33)S, (34)S) fractionation patterns in waters of hydrothermal pools are more consistent with redox processes involving intermediate sulfur species than with bacterial sulfate reduction. …CONCLUSIONS: The variation of sulfate isotopic compos …154Cite 

Uric acid and thiocyanate as competing substrates of lactoperoxidase.

Seidel A, Parker H, Turner R, Dickerhof N, Khalilova IS, Wilbanks SM, Kettle AJ, Jameson GN.J Biol Chem. 2014 Aug 8;289(32):21937-49. doi: 10.1074/jbc.M113.544957. Epub 2014 Jun 13.PMID: 24928513 Free PMC article.

LPO is a mammalian peroxidase that plays a key role in the innate immune defense by oxidizing thiocyanate to the bactericidal and fungicidal agent hypothiocyanite. We now demonstrate that urate is a good substrate for bovine LPO. …At physiologically relevant concentratio …155Cite 

Mechanism and regulation of peroxidase-catalyzed nitric oxide consumption in physiological fluids: critical protective actions of ascorbate and thiocyanate.

Rees MD, Maiocchi SL, Kettle AJ, Thomas SR.Free Radic Biol Med. 2014 Jul;72:91-103. doi: 10.1016/j.freeradbiomed.2014.03.037. Epub 2014 Apr 4.PMID: 24704973

We show that NO consumption by myeloperoxidase Compound I is significant in substrate-rich fluids and is resistant to competitive inhibition by ascorbate. However, thiocyanate effectively inhibits this process and yields hypothiocyanite at the expense of NO consumption. .. …156Cite 

Components of a standardised olive leaf dry extract (Ph. Eur.) promote hypothiocyanite production by lactoperoxidase.

Flemmig J, Rusch D, Czerwińska ME, Rauwald HW, Arnhold J.Arch Biochem Biophys. 2014 May 1;549:17-25. doi: 10.1016/j.abb.2014.03.006. Epub 2014 Mar 18.PMID: 24657078

By using excess hydrogen peroxide, we forced the accumulation of inactive enzymatic intermediates which are unable to promote the two-electronic oxidation of thiocyanate. Both OLE and certain extract components showed a strong LPO-reactivating effect. Thereby an o-hydroxyp …157Cite 

Effect of cross-linking of interfacial sodium caseinate by natural processing on the oxidative stability of oil-in-water (o/w) emulsions.

Phoon PY, Paul LN, Burgner JW 2nd, San Martin-Gonzalez MF, Narsimhan G.J Agric Food Chem. 2014 Apr 2;62(13):2822-9. doi: 10.1021/jf403285z. Epub 2014 Mar 18.PMID: 24606400

Oil oxidation was monitored by the ferric thiocyanate perioxide value assay. Higher homogenization pressure resulted in improved intrinsic emulsion oxidative stability, which is attributed to increased interfacial cross-linking as indicated by higher weighted average sedim …158Cite 

Synthesis, antioxidant, and antiacetylcholinesterase activities of sulfonamide derivatives of dopamine-related compounds.

Göçer H, Akıncıoğlu A, Öztaşkın N, Göksu S, Gülçin İ.Arch Pharm (Weinheim). 2013 Nov;346(11):783-92. doi: 10.1002/ardp.201300228. Epub 2013 Oct 8.PMID: 24591156

The antioxidant activities of the synthesized phenolic sulfonamides were investigated by thiocyanate method, 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS(+)), 1,1-diphenyl-2-picryl-hydrazyl (DPPH()), N,N-dimethyl-p-phenylenediamine (DMPD(+)), and superoxide …159Cite 

Wet oxidation of real coke wastewater containing high thiocyanate concentration.

Oulego P, Collado S, Garrido L, Laca A, Rendueles M, Díaz M.J Environ Manage. 2014 Jan;132:16-23. doi: 10.1016/j.jenvman.2013.10.011. Epub 2013 Nov 21.PMID: 24269931

A positive effect of the matrix of real coke wastewater was observed, resulting in faster thiocyanate degradation than was obtained with synthetic wastewaters. Besides, the effect of oxygen concentration and temperature on thiocyanate wet oxidation was more noticeab …160Cite 

Antileukemic Efficacy of Monomeric Manganese-Based Metal Complex on KG-1A and K562 Cell Lines.

Dash SK, Chattopadhyay S, Ghosh T, Tripathy S, Das S, Das D, Roy S.ISRN Oncol. 2013 Oct 8;2013:709269. doi: 10.1155/2013/709269. eCollection 2013.PMID: 24223312 Free PMC article.

In this background, recent studies demonstrate that monomeric manganese (MnII) thiocyanate complex (MMTC) holds great promise to exert effective antileukemic effects. MMTC was developed by a simple chemical reaction and characterized by elemental analyses, thermal analyses …161Cite 

Hypothiocyanous acid oxidation of tubulin cysteines inhibits microtubule polymerization.

Clark HM, Hagedorn TD, Landino LM.Arch Biochem Biophys. 2014 Jan 1;541:67-73. doi: 10.1016/j.abb.2013.10.026. Epub 2013 Nov 9.PMID: 24215946 Free PMC article.

Thiol oxidation is a probable outcome of cellular oxidative stress and is linked to degenerative disease progression. In addition, protein thiol redox reactions are increasingly identified as a mechanism to regulate protein structure and function. …162Cite 

Antioxidant/prooxidant effects of α-tocopherol, quercetin and isorhamnetin on linoleic acid peroxidation induced by Cu(II) and H2O2.

Bakır T, Sönmezoğlu I, Imer F, Apak R.Int J Food Sci Nutr. 2014 Mar;65(2):226-34. doi: 10.3109/09637486.2013.845654. Epub 2013 Oct 24.PMID: 24152374

Cu(II)-induced LA peroxidation followed pseudo-first-order kinetics with respect to primary (hydroperoxides) and secondary (aldehydes- and ketones-like) oxidation products, which were determined by ferric thiocyanate and thiobarbituric acid-reactive substances methods, res …163Cite 

Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells.

Lloyd MM, Grima MA, Rayner BS, Hadfield KA, Davies MJ, Hawkins CL.Free Radic Biol Med. 2013 Dec;65:1352-1362. doi: 10.1016/j.freeradbiomed.2013.10.007. Epub 2013 Oct 10.PMID: 24120969164Cite 

A reversible competition colorimetric assay for the detection of biothiols based on ruthenium-containing complex.

Hao Y, Xiong D, Wang L, Chen W, Zhou B, Liu YN.Talanta. 2013 Oct 15;115:253-7. doi: 10.1016/j.talanta.2013.04.076. Epub 2013 May 3.PMID: 24054588

A novel reversible colorimetric sensor, which based on a competitive ligation of Hg(2+) by thiols, cysteine (Cys) or glutathione (GSH), and thiocyanate (SCN) on the N3 dye (bis(4,4′-dicarboxy-2,2′-bipyridine) dithiocyanato ruthenium (II)), was developed for the detection o …165Cite 

[Study of antioxidant and membrane activity of rosmarinic acid using different model systems].

Popov AM, Osipov AN, Korepanova EA, Krivoshapko ON, Artiukov AA.Biofizika. 2013 Sep-Oct;58(5):775-85.PMID: 25481945 Russian.

Linoleic acid peroxidation was assessed by iron-thiocyanate method. In these studies, trolox was used as a reference antioxidant, and ascorbic acid, and dihydroquercetin were taken as standards. …166Cite 

Thiocyanate potentiates antimicrobial photodynamic therapy: in situ generation of the sulfur trioxide radical anion by singlet oxygen.

St Denis TG, Vecchio D, Zadlo A, Rineh A, Sadasivam M, Avci P, Huang L, Kozinska A, Chandran R, Sarna T, Hamblin MR.Free Radic Biol Med. 2013 Dec;65:800-810. doi: 10.1016/j.freeradbiomed.2013.08.162. Epub 2013 Aug 19.PMID: 23969112 Free PMC article.

In order to chemically enhance PDT by the formation of longer-lived radical species, we asked whether thiocyanate (SCN(-)) could potentiate the methylene blue (MB) and light-mediated killing of the gram-positive Staphylococcus aureus and the gram-negative Escherichia coli. …167Cite 

Spectroscopic studies on the antioxidant activity of p-coumaric acid.

Kiliç I, Yeşiloğlu Y.Spectrochim Acta A Mol Biomol Spectrosc. 2013 Nov;115:719-24. doi: 10.1016/j.saa.2013.06.110. Epub 2013 Jul 8.PMID: 23892112

In vitro radical scavenging and antioxidant capacity of p-coumaric acid were clarified using different analytical methodologies such as total antioxidant activity determination by ferric thiocyanate, hydrogen peroxide scavenging, 1,1-diphenyl-2-picryl-hydrazyl free radical …168Cite 

Electronic and interfacial behavior of gemini metallosurfactants with copper(II)/pseudohalide cascade cores.

Verani CN, Shanmugam R, Xavier FR, Allard MM, Kpogo KK.Dalton Trans. 2013 Nov 21;42(43):15296-306. doi: 10.1039/c3dt50788b.PMID: 23877838

Diagnostic IR stretches support the presence of mu1,1-bridged (end-on, 2075 cm(-1)) azide groups in 1 and mu1,3-bridged (end-to-end, 2117 cm(-1)) thiocyanate groups in 2. Anion-to-copper LMCT electronic processes at 390 and 440 nm for 1 and at 415 nm for 2 reinforce the na …169Cite 

Transcription factor Nrf2 protects renal dopamine D1 receptor function during oxidative stress.

Banday AA, Lokhandwala MF.Hypertension. 2013 Sep;62(3):512-7. doi: 10.1161/HYPERTENSIONAHA.113.01358. Epub 2013 Jul 22.PMID: 23876469

We investigated the role of nuclear factor E2-related factor 2 (Nrf2), a redox-sensitive transcription factor, in reducing oxidative stress, protecting renal D1R function and lowering BP in rats. …Treatment of rats with sulforaphane alone induced modest activation of Nrf …170Cite 

Selenocysteine confers resistance to inactivation by oxidation in thioredoxin reductase: comparison of selenium and sulfur enzymes.

Snider GW, Ruggles E, Khan N, Hondal RJ.Biochemistry. 2013 Aug 13;52(32):5472-81. doi: 10.1021/bi400462j. Epub 2013 Jul 31.PMID: 23865454 Free PMC article.171Cite 

Glutathione and γ-glutamylcysteine in hydrogen peroxide detoxification.

Quintana-Cabrera R, Bolaños JP.Methods Enzymol. 2013;527:129-44. doi: 10.1016/B978-0-12-405882-8.00007-6.PMID: 23830629

Hydrogen peroxide (H2O2) is an important regulator of cell redox status and signaling pathways. However, if produced in excess, it can trigger oxidative damage, which can be counteracted by the antioxidant systems. …Whereas most assays rely on coupled enzymatic reactions …172Cite 

Total phenolic, total flavonoid content, and antioxidant capacity of the leaves of Meyna spinosa Roxb., an Indian medicinal plant.

Sen S, De B, Devanna N, Chakraborty R.Chin J Nat Med. 2013 Mar;11(2):149-57. doi: 10.1016/S1875-5364(13)60042-4.PMID: 23787182

Total antioxidant activity of the extracts was estimated by the ferric thiocyanate method. Inhibition assay of lipid peroxidation and oxidative hemolysis were also performed to confirm the protective effect of the extracts. …173Cite 

Oxidation of thiocyanate with H2O2 catalyzed by [Ru(III)(edta)(H2O)]-.

Chatterjee D, Paul B, Mukherjee R.Dalton Trans. 2013 Jul 21;42(27):10056-60. doi: 10.1039/c3dt50723h. Epub 2013 May 29.PMID: 23714771

The [Ru(III)(edta)(H2O)](-) (edta(4-) = ethylenediaminetetraacetate) complex is shown to catalyze the oxidation of thiocyanate (SCN(-)) with H2O2 mimicking the action of peroxidases. The kinetics of the catalytic oxidation process was studied by using stopped-flow and rapi …174Cite 

Fluorescence quenching of protonated β-carbolines in water and microemulsions: evidence for heavy-atom and electron-transfer mechanisms.

Mousa SA, Douglas P, Burrows HD, Fonseca SM.Photochem Photobiol Sci. 2013 Sep;12(9):1606-14. doi: 10.1039/c3pp50044f.PMID: 23708826

The observation of the (SCN)2(-) transient in microemulsions demonstrates that it is possible to have the protonated beta-carboline and at least two thiocyanate ions in the same water pool….175Cite 

Antioxidant potential of phenolic extracts of Mimusops elengi.

Shahwar D, Raza MA.Asian Pac J Trop Biomed. 2012 Jul;2(7):547-50. doi: 10.1016/S2221-1691(12)60094-X.PMID: 23569968 Free PMC article.

Antioxidant activity of the extracts and partitioned fractions of M. elengi was evaluated in terms of radical scavenging potential (DPPH), inhibition of lipid peroxidation [ferric thiocyanate (FTC)], and total antioxidant activity (phosphomolybdate method). Total phenolics …176Cite 

Polar paradox revisited: analogous pairs of hydrophilic and lipophilic antioxidants in linoleic acid emulsion containing Cu(II).

Bakır T, Sönmezoğlu I, Imer F, Apak R.J Sci Food Agric. 2013 Aug 15;93(10):2478-85. doi: 10.1002/jsfa.6063. Epub 2013 Mar 20.PMID: 23520052

RESULTS: LA peroxidation induced by Cu(II) followed pseudo-first-order kinetics with respect to the formation of primary (hydroperoxides) and secondary (aldehyde- and ketone-like) oxidation products, which were determined by ferric thiocyanate (Fe(III)-SCN) and thiobarbitu …177Cite 

A series of inorganic solid nitrogen sources for the synthesis of metal nitride clusterfullerenes: the dependence of production yield on the oxidation state of nitrogen and counter ion.

Liu F, Guan J, Wei T, Wang S, Jiao M, Yang S.Inorg Chem. 2013 Apr 1;52(7):3814-22. doi: 10.1021/ic302436k. Epub 2013 Mar 12.PMID: 23480680

A series of nitrogen-containing inorganic solid compounds with variable oxidation states of nitrogen and counter ions have been successfully applied as new inorganic solid nitrogen sources toward the synthesis of Sc-based metal nitride clusterfullerenes (Sc-NCFs), including ammon …178Cite 

Two arginine residues in the substrate pocket predominantly control the substrate selectivity of thiocyanate hydrolase.

Yamanaka Y, Arakawa T, Watanabe T, Namima S, Sato M, Hori S, Ohtaki A, Noguchi K, Katayama Y, Yohda M, Odaka M.J Biosci Bioeng. 2013 Jul;116(1):22-7. doi: 10.1016/j.jbiosc.2013.01.013. Epub 2013 Mar 1.PMID: 23453853

Thiocyanate hydrolase (SCNase) of Thiobacillus thioparus THI115 is a cobalt (Co)-containing enzyme that catalyzes the hydrolysis of thiocyanate (SCN-), a major component of wastewater from coke oven factories, to carbonyl sulfide and ammonia. …179Cite 

Apoptotic role of natural isothiocyanate from broccoli (Brassica oleracea italica) in experimental chemical lung carcinogenesis.

Kalpana Deepa Priya D, Gayathri R, Gunassekaran GR, Murugan S, Sakthisekaran D.Pharm Biol. 2013 May;51(5):621-8. doi: 10.3109/13880209.2012.761242. Epub 2013 Feb 4.PMID: 23373711 Free article.180Cite 

Ambidentate thiocyanate and cyanate ligands in dinitrosyl iron complexes.

Hsieh CH, Brothers SM, Reibenspies JH, Hall MB, Popescu CV, Darensbourg MY.Inorg Chem. 2013 Feb 18;52(4):2119-24. doi: 10.1021/ic3025149. Epub 2013 Feb 1.PMID: 23373599

The nu(NO) IR values shift to lower values for 1 > 2 > (N(3))(2)Fe(NO)(2)(-) > (PhS)(2)Fe(NO)(2)(-), reflecting the increasing donor ability of the ancillary ligands and consistent with the redox potentials of the complexes, and the small trends in Mossbauer isome …181Cite 

Detailed kinetics and mechanism of the oxidation of thiocyanate ion (SCN-) by peroxomonosulfate ion (HSO5(-)). Formation and subsequent oxidation of hypothiocyanite ion (OSCN-).

Kalmár J, Lente G, Fábián I.Inorg Chem. 2013 Feb 18;52(4):2150-6. doi: 10.1021/ic302544y. Epub 2013 Jan 30.PMID: 23363374

The haloperoxidase-catalyzed in vivo oxidation of thiocyanate ion (SCN(-)) by H(2)O(2) is important for generation of the antimicrobial hypothiocyanite ion (OSCN(-)), which is also susceptible to oxidation by strong in vivo oxidizing agents (i.e., H(2)O(2), OCl(-), OBr(-)) …182Cite 

Effect of thermal behavior of β-lactoglobulin on the oxidative stability of menhaden oil-in-water emulsions.

Phoon PY, Narsimhan G, San Martin-Gonzalez MF.J Agric Food Chem. 2013 Feb 27;61(8):1954-67. doi: 10.1021/jf304834n. Epub 2013 Feb 18.PMID: 23356684

Oxidative stability was monitored by the ferric thiocyanate peroxide value assay. Higher oxidative stability was attained by beta-lactoglobulin in the molten globule state than in the native or denatured state. …183Cite 

Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation.

Bai Y, Cui W, Xin Y, Miao X, Barati MT, Zhang C, Chen Q, Tan Y, Cui T, Zheng Y, Cai L.J Mol Cell Cardiol. 2013 Apr;57:82-95. doi: 10.1016/j.yjmcc.2013.01.008. Epub 2013 Jan 23.PMID: 23353773184Cite 

Alcohol causes alveolar epithelial oxidative stress by inhibiting the nuclear factor (erythroid-derived 2)-like 2-antioxidant response element signaling pathway.

Jensen JS, Fan X, Guidot DM.Am J Respir Cell Mol Biol. 2013 Apr;48(4):511-7. doi: 10.1165/rcmb.2012-0334OC.PMID: 23306837 Free PMC article.

Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a redox-sensitive master transcription factor that regulates activation of the antioxidant response element (ARE). …185Cite 

Synthesis and antioxidant activity of O-alkyl selenocarbamates, selenoureas and selenohydantoins.

Merino-Montiel P, Maza S, Martos S, López Ó, Maya I, Fernández-Bolaños JG.Eur J Pharm Sci. 2013 Feb 14;48(3):582-92. doi: 10.1016/j.ejps.2012.12.016. Epub 2012 Dec 31.PMID: 23287366

Organoselenium compounds were also found to be capable of inhibiting the chain reaction involving lipid peroxidation (ferric thiocyanate method); thus, when tested at 0.74 mM, sugar selenocarbamates exhibited 49-71% inhibition of alkyl peroxides-mediated degradation of lin …186Cite 

Crystal structures of the HypCD complex and the HypCDE ternary complex: transient intermediate complexes during [NiFe] hydrogenase maturation.

Watanabe S, Matsumi R, Atomi H, Imanaka T, Miki K.Structure. 2012 Dec 5;20(12):2124-37. doi: 10.1016/j.str.2012.09.018. Epub 2012 Nov 1.PMID: 23123111 Free article.

The Fe(CN)(2)CO moiety of [NiFe] hydrogenases is assembled via unknown transient interactions among specific maturation proteins HypC (metallochaperone), HypD (redox protein), and HypE (cyanide synthesis/donor). Here, we report the structures of the HypC-HypD and HypC-HypD …187Cite 

Neuroprotective effects of erucin against 6-hydroxydopamine-induced oxidative damage in a dopaminergic-like neuroblastoma cell line.

Tarozzi A, Morroni F, Bolondi C, Sita G, Hrelia P, Djemil A, Cantelli-Forti G.Int J Mol Sci. 2012;13(9):10899-10910. doi: 10.3390/ijms130910899. Epub 2012 Aug 30.PMID: 23109827 Free PMC article.

The pretreatment of SH-SY5Y cells with ER was also shown to prevent the redox status impairment, in terms of intracellular ROS and O(2) (-) formation, and loss of mitochondrial membrane potential, early events that are initiators of the apoptotic process, induced by 6-OHDA …188Cite 

Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl).

Hadfield KA, Pattison DI, Brown BE, Hou L, Rye KA, Davies MJ, Hawkins CL.Biochem J. 2013 Jan 15;449(2):531-42. doi: 10.1042/BJ20121210.PMID: 23088652

The ability of HOSCN to impair apoA-I-mediated cholesterol efflux may contribute to the development of atherosclerosis, particularly in smokers who have high plasma levels of SCN- (thiocyanate)….189Cite 

Preventing protein oxidation with sugars: scavenging of hypohalous acids by 5-selenopyranose and 4-selenofuranose derivatives.

Storkey C, Pattison DI, White JM, Schiesser CH, Davies MJ.Chem Res Toxicol. 2012 Nov 19;25(11):2589-99. doi: 10.1021/tx3003593. Epub 2012 Oct 30.PMID: 23075063190Cite 

Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells.

Rees MD, Dang L, Thai T, Owen DM, Malle E, Thomas SR.Free Radic Biol Med. 2012 Dec 15;53(12):2344-56. doi: 10.1016/j.freeradbiomed.2012.10.002. Epub 2012 Oct 9.PMID: 23059132 Free PMC article.

Notably, diversion of MPO from HOCl production by thiocyanate or nitrite attenuated de-adhesion and associated signaling responses, despite the latter substrate supporting MPO-catalyzed fibronectin nitration. These data show that subendothelial-localized MPO employs a nove …191Cite 

Myeloperoxidase-derived oxidants rapidly oxidize and disrupt zinc-cysteine/histidine clusters in proteins.

Cook NL, Pattison DI, Davies MJ.Free Radic Biol Med. 2012 Dec 1;53(11):2072-80. doi: 10.1016/j.freeradbiomed.2012.09.033. Epub 2012 Sep 29.PMID: 23032100192Cite 

Phenylalkyl isoselenocyanates vs phenylalkyl isothiocyanates: thiol reactivity and its implications.

Crampsie MA, Pandey MK, Desai D, Spallholz J, Amin S, Sharma AK.Chem Biol Interact. 2012 Oct 25;200(1):28-37. doi: 10.1016/j.cbi.2012.08.022. Epub 2012 Sep 13.PMID: 22982772 Free PMC article.

Finally, the panels were tested for their ability to redox cycle when reacted with GSH to form superoxide and other reactive oxygen species (ROS). ISC compounds showed a much greater ability to redox cycle than corresponding ITCs, and were able to induce higher leve …193Cite 

Vascular peroxidase 1 catalyzes the formation of hypohalous acids: characterization of its substrate specificity and enzymatic properties.

Li H, Cao Z, Zhang G, Thannickal VJ, Cheng G.Free Radic Biol Med. 2012 Nov 15;53(10):1954-9. doi: 10.1016/j.freeradbiomed.2012.08.597. Epub 2012 Sep 12.PMID: 22982576 Free PMC article.194Cite 

Defensin protein from sweet potato (Ipomoea batatas [L.] Lam ‘Tainong 57’) storage roots exhibits antioxidant activities in vitro and ex vivo.

Huang GJ, Deng JS, Chen HJ, Huang SS, Liao JC, Hou WC, Lin YH.Food Chem. 2012 Dec 1;135(3):861-7. doi: 10.1016/j.foodchem.2012.05.082. Epub 2012 May 29.PMID: 22953797

Antioxidant status [2,2′-azinobis[3-ethylbenzthiazoline-6-sulphonic acid (ABTS) assay], scavenging activity against DPPH (1,1-dipheny-2-picrylhydrazyl) radical method, reducing power method, Fe(2+)-chelating ability, FTC (ferric thiocyanate) method, and protection of calf …195Cite 

In vitro protective effects of Thymus quinquecostatus Celak extracts on t-BHP-induced cell damage through antioxidant activity.

Kim YS, Lee SJ, Hwang JW, Kim EK, Kim SE, Kim EH, Moon SH, Jeon BT, Park PJ.Food Chem Toxicol. 2012 Nov;50(11):4191-8. doi: 10.1016/j.fct.2012.08.015. Epub 2012 Aug 17.PMID: 22921350

In addition, the extracts from the TQC leaf and stem showed stronger antioxidant activity than that of vitamin C, alpha-tocopherol in ferric thiocyanate (FTC) and thiobarbituric acid (TBA) methods. Cytoprotective and anti-apoptotic effect of water extracts from TQC was als …196Cite 

Label-free impedimetric immunosensor for ultrasensitive detection of cancer marker Murine double minute 2 in brain tissue.

Elshafey R, Tlili C, Abulrob A, Tavares AC, Zourob M.Biosens Bioelectron. 2013 Jan 15;39(1):220-5. doi: 10.1016/j.bios.2012.07.049. Epub 2012 Aug 3.PMID: 22898660

The assembly processes of the immunosensor had been monitored with cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) techniques using Fe(CN)(6)(3-/4-) solution as redox probe. The impedance changes upon binding of MDM2 protein to the sensor surface w …197Cite 

Oxidation of SCN- with air and micellar polyoxoperoxometalates.

Wei M, Chen X, Wang H, Li H, Wang Y, Wang X, Huo M.Chemosphere. 2013 Jan;90(2):318-22. doi: 10.1016/j.chemosphere.2012.07.015. Epub 2012 Aug 9.PMID: 22877935198Cite 

Major differences among chemopreventive organoselenocompounds in the sustained elevation of cytoprotective genes.

Poerschke RL, Franklin MR, Bild AH, Moos PJ.J Biochem Mol Toxicol. 2012 Sep;26(9):344-53. doi: 10.1002/jbt.21427. Epub 2012 Jul 16.PMID: 22807314 Free PMC article.

Cytoprotective enzyme elevation through the nuclear erythroid 2 p45-related factor 2 (Nrf2)-Kelch-like ECH-associated protein 1/antioxidant response element pathway has been promulgated for cancer prevention. This study compares the redox insult and sustained cytoprotectiv …199Cite 

Antioxidant sulforaphane and sensitizer trinitrobenzene sulfonate induce carboxylesterase-1 through a novel element transactivated by nuclear factor-E2 related factor-2.

Chen YT, Shi D, Yang D, Yan B.Biochem Pharmacol. 2012 Sep 15;84(6):864-71. doi: 10.1016/j.bcp.2012.06.025. Epub 2012 Jul 6.PMID: 22776248 Free PMC article.200Cite 

Cotinus coggyria: a rich source of antioxidants.

Riaz T, Abbasi MA, Aziz-ur-Rehman, Rubab K, Shahzadi T, Ajaib M, Khan KM.Pak J Pharm Sci. 2012 Jul;25(3):679-86.PMID: 22713961

Antioxidant activity of these four fractions and the left behind aqueous fraction was measured by four methods such as: 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity, ferric thiocyanate assay, ferric reducing antioxidant power (FRAP) assay and total …

201Cite 

Nuclear factor erythroid 2-related factor 2 nuclear translocation induces myofibroblastic dedifferentiation in idiopathic pulmonary fibrosis.

Artaud-Macari E, Goven D, Brayer S, Hamimi A, Besnard V, Marchal-Somme J, Ali ZE, Crestani B, Kerdine-Römer S, Boutten A, Bonay M.Antioxid Redox Signal. 2013 Jan 1;18(1):66-79. doi: 10.1089/ars.2011.4240. Epub 2012 Aug 6.PMID: 22703534 Free article.202Cite 

Review of the catalytic voltammetric determination of titanium traces.

Bobrowski A, Zarębski J.Acta Chim Slov. 2012 Jun;59(2):221-32.PMID: 24061234 Review.

In addition to a survey of literature (91 references), catalytic polarographic, voltammetric and catalytic adsorptive stripping voltammetric determination of titanium traces at liquid mercury and metallic films electrodes are discussed briefly. Moreover, the application of the …203Cite 

Antioxidant properties of various solvent extracts from purple basil.

Yeşiloğlu Y, Sit L.Spectrochim Acta A Mol Biomol Spectrosc. 2012 Sep;95:100-6. doi: 10.1016/j.saa.2012.04.036. Epub 2012 May 3.PMID: 22613128204Cite 

High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine.

Talib J, Pattison DI, Harmer JA, Celermajer DS, Davies MJ.Free Radic Biol Med. 2012 Jul 1;53(1):20-9. doi: 10.1016/j.freeradbiomed.2012.04.018. Epub 2012 Apr 27.PMID: 22609005

In previous studies we have demonstrated that smokers have elevated levels of thiocyanate ions (SCN(-)), relative to nonsmokers, and increased thiol oxidation, as SCN(-) is a favored substrate for MPO, and the resulting hypothiocyanous acid (HOSCN) targets thiol groups rap …205Cite 

Role of 4-hydroxynonenal in chemopreventive activities of sulforaphane.

Sharma R, Sharma A, Chaudhary P, Sahu M, Jaiswal S, Awasthi S, Awasthi YC.Free Radic Biol Med. 2012 Jun 1-15;52(11-12):2177-85. doi: 10.1016/j.freeradbiomed.2012.04.012. Epub 2012 Apr 23.PMID: 22579574 Free PMC article. Review.206Cite 

Crosstalk between Nrf2 and the proteasome: therapeutic potential of Nrf2 inducers in vascular disease and aging.

Chapple SJ, Siow RC, Mann GE.Int J Biochem Cell Biol. 2012 Aug;44(8):1315-20. doi: 10.1016/j.biocel.2012.04.021. Epub 2012 May 7.PMID: 22575091 Review.

In vascular models, activators of the transcription factor NF-E2 related factor 2 (Nrf2) pathway have been shown to restore redox homeostasis by increasing antioxidant/electrophilic response element-mediated (ARE/EpRE) expression of phase II and antioxidant enzymes, includ …207Cite 

Synthesis and bioactivity of pyrazole acyl thiourea derivatives.

Wu J, Shi Q, Chen Z, He M, Jin L, Hu D.Molecules. 2012 May 3;17(5):5139-50. doi: 10.3390/molecules17055139.PMID: 22555301 Free PMC article.

Thess were then reacted with ammonium thiocyanate in the presence of PEG-400 to afford 5-chloro-3-methyl-1-substituted-1H-pyrazole-4-carbonyl isothiocyanates 5. …208Cite 

Myeloperoxidase-derived chlorinating species induce protein carbamylation through decomposition of thiocyanate and urea: novel pathways generating dysfunctional high-density lipoprotein.

Holzer M, Zangger K, El-Gamal D, Binder V, Curcic S, Konya V, Schuligoi R, Heinemann A, Marsche G.Antioxid Redox Signal. 2012 Oct 15;17(8):1043-52. doi: 10.1089/ars.2011.4403. Epub 2012 May 8.PMID: 22462773 Free PMC article.

RESULTS: Here, we show that MPO-derived chlorinating species rapidly decompose the plasma components thiocyanate (SCN) and urea, thereby promoting (lipo)protein carbamylation. Strikingly, the presence of physiologic concentrations of SCN completely prevented MPO-induced 3- …209Cite 

In vitro assessment of relief to oxidative stress by different fractions of Boerhavia procumbens.

Abbasi MA, Rubab K, Rehman A, Riaz T, Shahzadi T, Khalid M, Ajaib M.Pak J Pharm Sci. 2012 Apr;25(2):357-64.PMID: 22459462

The antioxidant activity of all these fractions and the remaining aqueous fraction was evaluated by four methods such as: 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity, ferric reducing antioxidant power (FRAP) assay, total antioxidant activity and ferric …210Cite 

Decreased mucosal sulfide detoxification is related to an impaired butyrate oxidation in ulcerative colitis.

De Preter V, Arijs I, Windey K, Vanhove W, Vermeire S, Schuit F, Rutgeerts P, Verbeke K.Inflamm Bowel Dis. 2012 Dec;18(12):2371-80. doi: 10.1002/ibd.22949. Epub 2012 Mar 20.PMID: 22434643

The colonic mucosal thiosulfate sulfurtransferase (TST) enzyme removes H(2) S by conversion to the less toxic thiocyanate. In this study we measured colonic mucosal TST enzyme activity and gene expression in UC and controls. …211Cite 

In vitro antioxidant activity study of novel chromone derivatives.

Phosrithong N, Samee W, Nunthanavanit P, Ungwitayatorn J.Chem Biol Drug Des. 2012 Jun;79(6):981-9. doi: 10.1111/j.1747-0285.2012.01368.x. Epub 2012 Mar 21.PMID: 22381130

Forty-eight chromone derivatives were evaluated for their antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl free radical scavenging assay, ferrous ions (Fe(2+) ) chelating activity test, total antioxidant activity test (Ferric thiocyanate and Thiobarbituric acid met …212Cite 

Antioxidant activity and protective effect of anthocyanin oligomers on H₂O₂-triggered G2/M arrest in retinal cells.

Hwang JW, Kim EK, Lee SJ, Kim YS, Moon SH, Jeon BT, Sung SH, Kim ET, Park PJ.J Agric Food Chem. 2012 May 2;60(17):4282-8. doi: 10.1021/jf205321j. Epub 2012 Apr 17.PMID: 22380882

The inhibitory effect of anthocyanin oligomers on lipid peroxidation was examined with ferric thiocyanate (FTC) and thiobarbituric acid (TBA). The inhibitory activity of anthocyanin oligomers was found to be comparable to that of vitamin E. …213Cite 

Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids.

Pattison DI, Davies MJ, Hawkins CL.Free Radic Res. 2012 Aug;46(8):975-95. doi: 10.3109/10715762.2012.667566. Epub 2012 Apr 23.PMID: 22348603 Review.

The major reactive species produced by MPO under physiological conditions are hypochlorous acid (HOCl) and hypothiocyanous acid (HOSCN), with the ratio of these oxidants critically dependent on the concentration of thiocyanate ions (SCN-). The reactivity and selectivity of …214Cite 

Protective effect of sulphoraphane against oxidative stress mediated toxicity induced by CuO nanoparticles in mouse embryonic fibroblasts BALB 3T3.

Akhtar MJ, Ahamed M, Fareed M, Alrokayan SA, Kumar S.J Toxicol Sci. 2012 Feb;37(1):139-48. doi: 10.2131/jts.37.139.PMID: 22293418 Free article.215Cite 

Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates.

Barrett TJ, Pattison DI, Leonard SE, Carroll KS, Davies MJ, Hawkins CL.Free Radic Biol Med. 2012 Mar 15;52(6):1075-85. doi: 10.1016/j.freeradbiomed.2011.12.024. Epub 2012 Jan 8.PMID: 22248862 Free PMC article.

Although HOSCN is a major MPO oxidant, particularly in smokers, who have elevated plasma thiocyanate, the role of this oxidant in disease is poorly characterized. HOSCN induces cellular damage by targeting thiols. …This is the first direct evidence for the formation of p …216Cite 

Neutral gold complexes with tridentate SNS thiosemicarbazide ligands.

Maia PI, Nguyen HH, Ponader D, Hagenbach A, Bergemann S, Gust R, Deflon VM, Abram U.Inorg Chem. 2012 Feb 6;51(3):1604-13. doi: 10.1021/ic201905t. Epub 2012 Jan 10.PMID: 22233323

However, systematic variation of the alkyl groups in the N(4)-position of the thiosemicarbazone building blocks as well as the replacement of the chloride by thiocyanate ligands do not considerably influence the biological activity. On the other hand, the reduction of Au(I …217Cite 

Apoptosis, antimicrobial and antioxidant activities of phytochemicals from Garcinia malaccensis Hk.f.

Taher M, Susanti D, Rezali MF, Zohri FS, Ichwan SJ, Alkhamaiseh SI, Ahmad F.Asian Pac J Trop Med. 2012 Feb;5(2):136-41. doi: 10.1016/S1995-7645(12)60012-1.PMID: 22221758 Free article.

Antibacterial activity was conducted by disc diffusion and microdilution methods, whereas antioxidant activities were done by ferric thiocyanate method and DPPH radical scavenging. RESULTS: The phytochemical study led to the isolation of alpha,beta-mangostin and cycloart-2 …218Cite 

Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells.

Cook NL, Viola HM, Sharov VS, Hool LC, Schöneich C, Davies MJ.Free Radic Biol Med. 2012 Mar 1;52(5):951-61. doi: 10.1016/j.freeradbiomed.2011.12.001. Epub 2011 Dec 23.PMID: 22214747 Free PMC article.219Cite 

Enhancement of iron(II)-dependent reduction of nitrite to nitric oxide by thiocyanate and accumulation of iron(II)/thiocyanate/nitric oxide complex under conditions simulating the mixture of saliva and gastric juice.

Takahama U, Hirota S.Chem Res Toxicol. 2012 Jan 13;25(1):207-15. doi: 10.1021/tx200438q. Epub 2011 Dec 28.PMID: 22145785220Cite 

Nrf2 and NF-κB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucose-induced changes.

Negi G, Kumar A, Sharma SS.Curr Neurovasc Res. 2011 Nov;8(4):294-304. doi: 10.2174/156720211798120972.PMID: 22023613221Cite 

Thiocyanate-capped PbS nanocubes: ambipolar transport enables quantum dot based circuits on a flexible substrate.

Koh WK, Saudari SR, Fafarman AT, Kagan CR, Murray CB.Nano Lett. 2011 Nov 9;11(11):4764-7. doi: 10.1021/nl202578g. Epub 2011 Oct 24.PMID: 22011060

We report the use of thiocyanate as a ligand for lead sulfide (PbS) nanocubes for high-performance, thin-film electronics. PbS nanocubes, self-assembled into thin films and capped with the thiocyanate, exhibit ambipolar characteristics in field-effect transistors. T …222Cite 

Sulforaphane inhibits mitochondrial permeability transition and oxidative stress.

Greco T, Shafer J, Fiskum G.Free Radic Biol Med. 2011 Dec 15;51(12):2164-71. doi: 10.1016/j.freeradbiomed.2011.09.017. Epub 2011 Sep 21.PMID: 21986339 Free PMC article.

This study tested the hypothesis that treatment of rats with sulforaphane (SFP), an activator of the Nrf2 pathway of antioxidant gene expression, increases the resistance of liver mitochondria to redox-regulated PTP opening and elevates mitochondrial levels of antioxidants …223Cite 

Structure reactivity relationship in the reaction of DNA guanyl radicals with hydroxybenzoates.

Do TT, Tang VJ, Aguilera JA, Milligan JR.Radiat Phys Chem Oxf Engl 1993. 2010 Nov 1;79(1):1144-1148. doi: 10.1016/j.radphyschem.2010.06.006.PMID: 21966099 Free PMC article.

We have modeled this process by employing gamma irradiation in the presence of thiocyanate ions, a method which also produces single electron oxidized guanyl radicals in plasmid DNA in aqueous solution. …A comparison of the rates of these reactions with the redox …224Cite 

Antioxidant protective effect of flavonoids on linoleic acid peroxidation induced by copper(II)/ascorbic acid system.

Beker BY, Bakır T, Sönmezoğlu I, Imer F, Apak R.Chem Phys Lipids. 2011 Nov;164(8):732-9. doi: 10.1016/j.chemphyslip.2011.09.001. Epub 2011 Sep 9.PMID: 21925488

The extent of copper-initiated peroxide production in a LA system assayed by ferric thiocyanate method was used to determine possible antioxidant and prooxidant activities of the added flavonoids. …225Cite 

Assessment of cassava toxicity in patients with tropical chronic pancreatitis.

Girish BN, Rajesh G, Vaidyanathan K, Balakrishnan V.Trop Gastroenterol. 2011 Apr-Jun;32(2):112-6.PMID: 21922874

In this study we aimed to estimate cyanogens detoxifying enzyme rhodanese, thiocyanate and sulfur containing amino acids in cassava consumer as well as cassava non-consumer TCP patients and healthy controls and compare the same. …Serum thiocyanate was significantl …226Cite 

Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage.

Skaff O, Pattison DI, Morgan PE, Bachana R, Jain VK, Priyadarsini KI, Davies MJ.Biochem J. 2012 Jan 1;441(1):305-16. doi: 10.1042/BJ20101762.PMID: 21892922 Free PMC article.227Cite 

High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase.

Morgan PE, Pattison DI, Talib J, Summers FA, Harmer JA, Celermajer DS, Hawkins CL, Davies MJ.Free Radic Biol Med. 2011 Nov 1;51(9):1815-22. doi: 10.1016/j.freeradbiomed.2011.08.008. Epub 2011 Aug 18.PMID: 21884783

We hypothesized that smokers would have a high level of thiocyanate (SCN(-)), a preferred substrate for MPO, which in turn would predispose to thiol oxidation, an established independent risk factor for atherosclerosis. …228Cite 

Isoeugenol-based novel potent antioxidants: synthesis and reactivity.

Fındık E, Ceylan M, Elmastaş M.Eur J Med Chem. 2011 Sep;46(9):4618-24. doi: 10.1016/j.ejmech.2011.07.041. Epub 2011 Jul 28.PMID: 21843909

Antioxidant and radical scavenging activities of synthesized compounds (7-12) were determined by using various in vitro assays such as 1,1-diphenyl-2-picrylhydrazyl free radicals (DPPH), 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radicals (ABTS(+)), and superoxide anio …229Cite 

Quinoprotein adducts accumulate in the substantia nigra of aged rats and correlate with dopamine-induced toxicity in SH-SY5Y cells.

Wang N, Wang Y, Yu G, Yuan C, Ma J.Neurochem Res. 2011 Nov;36(11):2169-75. doi: 10.1007/s11064-011-0541-z. Epub 2011 Jul 22.PMID: 21785836230Cite 

Inhibition of premature death by isothiocyanates through immune restoration in LP-BM5 leukemia retrovirus-infected C57BL/6 mice.

Ho JN, Kang ER, Yoon HG, Jeon H, Jun W, Watson RR, Lee J.Biosci Biotechnol Biochem. 2011;75(7):1234-9. doi: 10.1271/bbb.100840. Epub 2011 Jul 7.PMID: 21737943 Free article.231Cite 

Influence of electrolyte co-additives on the performance of dye-sensitized solar cells.

Stergiopoulos T, Rozi E, Karagianni CS, Falaras P.Nanoscale Res Lett. 2011 Apr 7;6(1):307. doi: 10.1186/1556-276X-6-307.PMID: 21711833 Free PMC article.

The presence of specific chemical additives in the redox electrolyte results in an efficient increase of the photovoltaic performance of dye-sensitized solar cells (DSCs). …In a comparative work, we investigated in detail the action of TBP and NMBI additives in ionic liq …232Cite 

Effect of oxidation on surface-enhanced Raman scattering activity of silver nanoparticles: a quantitative correlation.

Han Y, Lupitskyy R, Chou TM, Stafford CM, Du H, Sukhishvili S.Anal Chem. 2011 Aug 1;83(15):5873-80. doi: 10.1021/ac2005839. Epub 2011 Jul 13.PMID: 21644591233Cite 

Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties.

Göçer H, Gülçin I.Int J Food Sci Nutr. 2011 Dec;62(8):821-5. doi: 10.3109/09637486.2011.585963. Epub 2011 Jun 2.PMID: 21631390

The aim of this study was to determine the antioxidant activity of CAPE using different methods such as total antioxidant activity by the thiocyanate method, 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid radicals, 1,1-diphenyl-2-picryl-hydrazyl free radicals, N,N-d …234Cite 

Encapsulation of astaxanthin-rich Xanthophyllomyces dendrorhous for antioxidant delivery.

Lee JS, Park SA, Chung D, Lee HG.Int J Biol Macromol. 2011 Oct 1;49(3):268-73. doi: 10.1016/j.ijbiomac.2011.04.021. Epub 2011 May 7.PMID: 21575657235Cite 

Monomeric, trimeric, and tetrameric transition metal complexes (Mn, Fe, Co) containing N,N-bis(2-pyridylmethyl)-2-aminoethanol/-ate: preparation, crystal structure, molecular magnetism and oxidation catalysis.

Shin JW, Rowthu SR, Hyun MY, Song YJ, Kim C, Kim BG, Min KS.Dalton Trans. 2011 Jun 7;40(21):5762-73. doi: 10.1039/c1dt10028a. Epub 2011 Apr 27.PMID: 21523305

In complex 1 the Mn(II) is bonded to one bpaeOH and two thiocyanate ions, while in complex 2 it is coordinated to a deprotonated bpaeO(-) and two azide ions. …The structures of monomeric iron(II) and cobalt(II) complexes 3 and 5 with two thiocyanate ions are isomo …236Cite 

Chemopreventive role of sulforaphane by upholding the GSH redox cycle in pre- and post-initiation phases of experimental lung carcinogenesis.

Priya DK, Gayathri R, Gunassekaran G, Murugan S, Sakthisekaran D.Asian Pac J Cancer Prev. 2011;12(1):103-10.PMID: 21517240 Free article.

Sulforaphane, supplemented orally at a dose of 9mumoles /mouse/day was found to greatly lessen the damaging effects of B(a)P in mice by increasing the availability of reducing equivalents to fulfil the futile GSH redox cycle and replenish GSH biosynthesis, stabilizing the …237Cite 

Nrf2 inhibits LXRα-dependent hepatic lipogenesis by competing with FXR for acetylase binding.

Kay HY, Kim WD, Hwang SJ, Choi HS, Gilroy RK, Wan YJ, Kim SG.Antioxid Redox Signal. 2011 Oct 15;15(8):2135-46. doi: 10.1089/ars.2010.3834. Epub 2011 Jun 13.PMID: 21504366 Free PMC article.238Cite 

A new type of dye-sensitized solar cell with a multilayered photoanode prepared by a film-transfer technique.

Miao Q, Wu L, Cui J, Huang M, Ma T.Adv Mater. 2011 Jun 24;23(24):2764-8. doi: 10.1002/adma.201100820. Epub 2011 Apr 15.PMID: 21495092 No abstract available.239Cite 

In vitro antioxidant and radical scavenging of Guinean kinkeliba leaf (Combretum micranthum G. Don) extracts.

Touré A, Xu X, Michel T, Bangoura M.Nat Prod Res. 2011 Jul;25(11):1025-36. doi: 10.1080/14786419.2010.482048.PMID: 21480049

The antioxidant properties of the water and ethanol leaf extracts of kinkeliba (Combretum micranthum) were investigated, including scavenging of the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical (IC50 values: 8.02 0.34 for the ethanol extract [KE] and 9.1 0.28 for the water extrac …240Cite 

Mechanochemical synthesis in copper(II) halide/pyridine systems: single crystal X-ray diffraction and IR spectroscopic studies.

Bowmaker GA, Di Nicola C, Pettinari C, Skelton BW, Somers N, White AH.Dalton Trans. 2011 May 14;40(18):5102-15. doi: 10.1039/c1dt10224a. Epub 2011 Mar 29.PMID: 21445441

[(py)(2)Cu(mu-I)(2)Cu(py)(2)] (structurally defined). Bromide or N-thiocyanate may be substituted for the unbound iodide ion in the solvated salt, resulting in complexes which crystallize in space group Ccca, but with both anions and the metal atom disordered. …Several o …241Cite 

Enhancement of respiratory mucosal antiviral defenses by the oxidation of iodide.

Fischer AJ, Lennemann NJ, Krishnamurthy S, Pócza P, Durairaj L, Launspach JL, Rhein BA, Wohlford-Lenane C, Lorentzen D, Bánfi B, McCray PB Jr.Am J Respir Cell Mol Biol. 2011 Oct;45(4):874-81. doi: 10.1165/rcmb.2010-0329OC. Epub 2011 Mar 25.PMID: 21441383 Free PMC article.

The other components include epithelial ion transporters, which mediate the secretion of the oxidizable anion thiocyanate (SCN(-)) into airway surface liquid, and lactoperoxidase (LPO), which catalyzes the H(2)O(2)-dependent oxidation of the pseudohalide SCN(-) to yield th …242Cite 

A new family of heteroleptic ruthenium(II) polypyridyl complexes for sensitization of nanocrystalline TiO2 films.

Giribabu L, Bessho T, Srinivasu M, Vijaykumar C, Soujanya Y, Reddy VG, Reddy PY, Yum JH, Grätzel M, Nazeeruddin MK.Dalton Trans. 2011 May 7;40(17):4497-504. doi: 10.1039/c0dt01417f. Epub 2011 Mar 14.PMID: 21403942

Two new heteroleptic ruthenium(II) photosensitizers that contains 2,2′;6,2”-terpyridine with extended pi-conjugation with donor groups, a 4,4′-dicarboxylic acid-2,2′-bipyridine anchoring ligand and a thiocyanate ligand have been designed, synthesized and fully characteriz …243Cite 

Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions.

Lorentzen D, Durairaj L, Pezzulo AA, Nakano Y, Launspach J, Stoltz DA, Zamba G, McCray PB Jr, Zabner J, Welsh MJ, Nauseef WM, Bánfi B.Free Radic Biol Med. 2011 May 1;50(9):1144-50. doi: 10.1016/j.freeradbiomed.2011.02.013. Epub 2011 Feb 18.PMID: 21334431 Free PMC article.

A recently discovered enzyme system produces antibacterial hypothiocyanite (OSCN(-)) in the airway lumen by oxidizing the secreted precursor thiocyanate (SCN(-)). Airway epithelial cultures have been shown to secrete SCN(-) in a CFTR-dependent manner. …244Cite 

Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages.

Harada N, Kanayama M, Maruyama A, Yoshida A, Tazumi K, Hosoya T, Mimura J, Toki T, Maher JM, Yamamoto M, Itoh K.Arch Biochem Biophys. 2011 Apr 1;508(1):101-9. doi: 10.1016/j.abb.2011.02.001. Epub 2011 Feb 12.PMID: 21303654

In this study, we demonstrated genetically that a redox-sensitive transcription factor, Nrf2, regulates Fpn1 mRNA expression in macrophages. …245Cite 

Low temperature removal of inorganic sulfur compounds from mining process waters.

Liljeqvist M, Sundkvist JE, Saleh A, Dopson M.Biotechnol Bioeng. 2011 Jun;108(6):1251-9. doi: 10.1002/bit.23057. Epub 2011 Jan 28.PMID: 21280027

Mining process waters may also contain inhibiting substances such as thiocyanate from cyanidation plants. However, toxicity experiments suggested their expected concentrations would not inhibit thiosalt oxidation by Acidithiobacillus ferrivorans SS3. …246Cite 

Pharmacological targeting of the transcription factor Nrf2 at the basal ganglia provides disease modifying therapy for experimental parkinsonism.

Jazwa A, Rojo AI, Innamorato NG, Hesse M, Fernández-Ruiz J, Cuadrado A.Antioxid Redox Signal. 2011 Jun 15;14(12):2347-60. doi: 10.1089/ars.2010.3731. Epub 2011 Mar 28.PMID: 21254817 Free article.247Cite 

Antioxidant and free radical scavenging activities of some fruits.

Prakash D, Upadhyay G, Pushpangadan P, Gupta C.J Complement Integr Med. 2011 Jan;8. doi: 10.2202/1553-3840.1513.PMID: 22754941

They also showed better inhibition of lipid peroxidation measured by using ferric thiocyanate assay and by using egg yolk compared to the reference standard quercetin. The ferrous and ferric ion chelating capacity of the promising fruits and their underutilized parts in te …248Cite 

Brain mitochondria from rats treated with sulforaphane are resistant to redox-regulated permeability transition.

Greco T, Fiskum G.J Bioenerg Biomembr. 2010 Dec;42(6):491-7. doi: 10.1007/s10863-010-9312-9.PMID: 21061051 Free PMC article.

This study tested the hypothesis that administration of SFP to normal rats increases resistance of isolated brain mitochondria to redox-sensitive PTP opening. SFP or DMSO vehicle was administered intraperitoneally to adult male rats at 10 mg/kg 40 h prior to isolation of n …249Cite 

Conformational analysis and design of cross-strand disulfides in antiparallel β-sheets.

Indu S, Kochat V, Thakurela S, Ramakrishnan C, Varadarajan R.Proteins. 2011 Jan;79(1):244-60. doi: 10.1002/prot.22878.PMID: 21058397

All Top7 mutants were characterized for stability through guanidinium thiocyanate chemical denaturation. Both exposed and two of the three buried NHB mutants were appreciably stabilized. …All four exposed Top7 disulfide mutants showed mild redox activity….250Cite 

A sensitive spectrophotometric method for the determination of propranolol HCl based on oxidation bromination reactions.

El-Didamony AM.Drug Test Anal. 2010 Mar;2(3):122-9. doi: 10.1002/dta.103.PMID: 20878893

The residual bromine (in method B), is treated with excess of iron(II) and the resulting iron(III) is complexed with thiocyanate and the absorbance is measured at 480 nm. Method C involves treating the unreacted bromine with a measured excess of iron(II) and the remaining …251Cite 

Bio-guided isolation of antioxidant compounds from Chrysophyllum perpulchrum, a plant used in the Ivory Coast pharmacopeia.

Philippe BA, Karine N, Barthélemy AK, Noél ZG, David NJ, Joseph DA, Hosttetmann K.Molecules. 2010 Sep 13;15(9):6386-98. doi: 10.3390/molecules15096386.PMID: 20877230 Free PMC article.

In the present study, the antioxidative and radical-scavenging activities of the methanolic extract were studied with three standard biological tests: DPPH reduction, ferric thiocyanate (FTC) lipidic peroxidation inhibition and thiobarbituric acid reacting substances (TBAR …252Cite 

Use of metallopeptide based mimics demonstrates that the metalloprotein nitrile hydratase requires two oxidized cysteinates for catalytic activity.

Shearer J, Callan PE, Amie J.Inorg Chem. 2010 Oct 4;49(19):9064-77. doi: 10.1021/ic101765h.PMID: 20831172 Free PMC article.

Nitrile hydratases (NHases) are non-heme Fe(III) or non-corrin Co(III) containing metalloenzymes that possess an N(2)S(3) ligand environment with nitrogen donors derived from amidates and sulfur donors derived from cysteinates. A closely related enzyme is thiocyanate hydro …253Cite 

Antioxidant properties of Urtica pilulifera root, seed, flower, and leaf extract.

Ozen T, Cöllü Z, Korkmaz H.J Med Food. 2010 Oct;13(5):1224-31. doi: 10.1089/jmf.2009.1303.PMID: 20828318

Antioxidative activity of the extracts was measured using the ferric thiocyanate method, thiobarbituric acid method, reductive potential, metal chelating, free radical, superoxide anion radical, and hydrogen peroxide scavenging activity. …254Cite 

Euphorbia peroxidase catalyzes thiocyanate oxidation in two different ways, the distal calcium ion playing an essential role.

Pintus F, Spanò D, Bellelli A, Angelucci F, Scorciapino AM, Anedda R, Medda R, Floris G.Biochemistry. 2010 Oct 12;49(40):8739-47. doi: 10.1021/bi1007854. Epub 2010 Sep 16.PMID: 20822104

The oxidation of the pseudohalide thiocyanate (SCN(-)) by Euphorbia peroxidase, in the presence or absence of added calcium, is investigated. After incubation of the native enzyme with hydrogen peroxide, the formation of Compound I occurs and serves to catalyze the thio …255Cite 

Hypertonic saline increases lung epithelial lining fluid glutathione and thiocyanate: two protective CFTR-dependent thiols against oxidative injury.

Gould NS, Gauthier S, Kariya CT, Min E, Huang J, Brian DJ.Respir Res. 2010 Aug 27;11(1):119. doi: 10.1186/1465-9921-11-119.PMID: 20799947 Free PMC article.

CFTR mutations lead to decreased levels of glutathione (GSH) and thiocyanate (SCN) in the epithelial lining fluid (ELF). Hypertonic saline is used to improve lung function however the mechanism is uncertain. …256Cite 

Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis.

Thomson E, Brennan S, Senthilmohan R, Gangell CL, Chapman AL, Sly PD, Kettle AJ; Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF); Balding E, Berry LJ, Carlin JB, Carzino R, de Klerk N, Douglas T, Foo C, Garratt LW, Hall GL, Harrison J, Kicic A, Laing IA, Logie KM, Massie J, Mott LS, Murray C, Parsons F, Pillarisetti N, Poreddy SR, Ranganathan SC, Robertson CF, Robins-Browne R, Robinson PJ, Skoric B, Stick SM, Sutanto EN, Williamson E.Free Radic Biol Med. 2010 Nov 15;49(9):1354-60. doi: 10.1016/j.freeradbiomed.2010.07.010. Epub 2010 Jul 18.PMID: 20647044

BAL fluid was analyzed for MPO, halogenated tyrosines as markers of hypohalous acids, thiocyanate, and protein carbonyls. MPO was the only peroxidase detected in BAL samples from children with CF and its concentration was markedly higher than in controls. …They correlate …257Cite 

Kinetic and thermodynamic resolution of the interactions between sulfite and the pentahaem cytochrome NrfA from Escherichia coli.

Kemp GL, Clarke TA, Marritt SJ, Lockwood C, Poock SR, Hemmings AM, Richardson DJ, Cheesman MR, Butt JN.Biochem J. 2010 Oct 1;431(1):73-80. doi: 10.1042/BJ20100866.PMID: 20629638

Under comparable conditions Km values of ~22 and ~300 muM describe nitrite and nitric oxide reduction respectively, whereas the affinities of nitrate and thiocyanate for NrfA fall more than 50-fold on enzyme reduction. These results are discussed in terms of the nature of …258Cite 

Hypothiocyanous acid is a potent inhibitor of apoptosis and caspase 3 activation in endothelial cells.

Bozonet SM, Scott-Thomas AP, Nagy P, Vissers MC.Free Radic Biol Med. 2010 Sep 15;49(6):1054-63. doi: 10.1016/j.freeradbiomed.2010.06.028. Epub 2010 Jul 13.PMID: 20615463259Cite 

Antioxidative activities of histidine containing caffeic acid-dipeptides.

Seo HS, Kwak SY, Lee YS.Bioorg Med Chem Lett. 2010 Jul 15;20(14):4266-72. doi: 10.1016/j.bmcl.2010.04.135. Epub 2010 May 6.PMID: 20542693

The antioxidative activities were measured using 2,2′-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging test and lipid peroxidation test with ferric thiocyanate method. Some of the CA-His dipeptides exhibited better radical scavenging activities than CA, and all of the C …260Cite 

Reduction of electron deficient guanine radical species in plasmid DNA by tyrosine derivatives.

Tsoi M, Do TT, Tang VJ, Aguilera JA, Milligan JR.Org Biomol Chem. 2010 Jun 7;8(11):2553-9. doi: 10.1039/b922749k. Epub 2010 Mar 24.PMID: 20485790

As a model for this process we have used gamma-irradiation in the presence of thiocyanate ions to generate single electron oxidized guanine radicals in a plasmid target in aqueous solution. …261Cite 

An atomistic picture of the regeneration process in dye sensitized solar cells.

Schiffmann F, Vandevondele J, Hutter J, Urakawa A, Wirz R, Baiker A.Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4830-3. doi: 10.1073/pnas.0913277107. Epub 2010 Mar 5.PMID: 20207948 Free PMC article.

In situ vibrational spectroscopy confirms the reversible binding of I(2) to the thiocyanate group. Additionally, simulations of the electrolyte near the interface suggest that acetonitrile is able to cover the (101) surface of anatase with a passivating layer that inhibits …262Cite 

Role of lipid peroxidation in cellular responses to D,L-sulforaphane, a promising cancer chemopreventive agent.

Sharma R, Sharma A, Chaudhary P, Pearce V, Vatsyayan R, Singh SV, Awasthi S, Awasthi YC.Biochemistry. 2010 Apr 13;49(14):3191-202. doi: 10.1021/bi100104e.PMID: 20205397 Free PMC article.263Cite 

Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis.

Niso-Santano M, González-Polo RA, Bravo-San Pedro JM, Gómez-Sánchez R, Lastres-Becker I, Ortiz-Ortiz MA, Soler G, Morán JM, Cuadrado A, Fuentes JM; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED).Free Radic Biol Med. 2010 May 15;48(10):1370-81. doi: 10.1016/j.freeradbiomed.2010.02.024. Epub 2010 Mar 2.PMID: 20202476

In a search for a physiological pathway that might counterbalance PQ-induced ASK1 activation, we analyzed the role of the transcription factor Nrf2, master regulator of redox homeostasis, and its target thioredoxin (Trx), which binds and inhibits ASK1. Trx levels were unde …264Cite 

Latest news about the sulfurtransferase protein family of higher plants.

Papenbrock J, Guretzki S, Henne M.Amino Acids. 2011 Jun;41(1):43-57. doi: 10.1007/s00726-010-0478-6. Epub 2010 Feb 5.PMID: 20135153 Review.

The best characterized Str is bovine rhodanese (EC 2.8.1.1) which catalyses in vitro the transfer of a sulfane sulfur atom from thiosulfate to cyanide, leading to the formation of sulfite and thiocyanate. Plants as well as other organisms contain many proteins carrying a t …265Cite 

Small molecular, macromolecular, and cellular chloramines react with thiocyanate to give the human defense factor hypothiocyanite.

Xulu BA, Ashby MT.Biochemistry. 2010 Mar 9;49(9):2068-74. doi: 10.1021/bi902089w.PMID: 20085320 Free PMC article.

Thiocyanate reacts noncatalytically with myeloperoxidase-derived HOCl to produce hypothiocyanite (OSCN(-)), thereby potentially limiting the propensity of HOCl to inflict host tissue damage that can lead to inflammatory diseases. …Our observations are further evidence fo …266Cite 

Utilization of oxidation reactions for the spectrophotometric determination of captopril using brominating agents.

El-Didamony AM, Erfan EA.Spectrochim Acta A Mol Biomol Spectrosc. 2010 Mar;75(3):1138-45. doi: 10.1016/j.saa.2009.12.075. Epub 2010 Jan 6.PMID: 20080436

In method (C), the surplus bromine is treated with excess of iron(II) and the resulting iron(III) is complexed with thiocyanate and the absorbance is measured at 478 nm. In all the methods, the amount of bromine reacted corresponds to the drug content. …267Cite 

Heterogeneous electron transfer kinetics and electrocatalytic behaviour of mixed self-assembled ferrocenes and SWCNT layers.

Nkosi D, Pillay J, Ozoemena KI, Nouneh K, Oyama M.Phys Chem Chem Phys. 2010 Jan 21;12(3):604-13. doi: 10.1039/b918754e. Epub 2009 Nov 16.PMID: 20066346

Using cyclic voltammetry and electrochemical impedance spectroscopy, the impact of neighbouring SWCNTs on the electron transfer dynamics of the ferrocene molecular assemblies in an acidic medium (0.5 M H(2)SO(4)) and in a solution of an outer-sphere redox probe ([Fe(CN)(6) …268Cite 

Kinetic model of the H(2)O(2)-SCN(-)-OH(-)-Cu(2+) oscillator and its application to the interpretation of the potentiometric responses of various inert electrodes monitoring the reaction course.

Wiśniewski A, Pekala K, Orlik M.J Phys Chem A. 2010 Jan 14;114(1):183-90. doi: 10.1021/jp907558n.PMID: 20055515

Thus, even the opposite phases of the potentiometric oscillations are explainable in terms of the oscillatory behavior of the same redox couple. Understanding of such phenomena is crucial for the proper interpretation of potentiometric data in complex chemical systems….269Cite 

Catalytic wet oxidation of thiocyanate with homogeneous copper(II) sulphate catalyst.

Collado S, Laca A, Díaz M.J Hazard Mater. 2010 May 15;177(1-3):183-9. doi: 10.1016/j.jhazmat.2009.12.015. Epub 2009 Dec 5.PMID: 20045245

The effects of copper concentration, initial thiocyanate concentration, pressure and temperature on the reaction rate were analyzed and the main products of reaction were identified. …A mechanistic model based on the formation of a transition complex between a copper cat …270Cite 

In vitro studies on the antioxidant and protective effect of 2-substituted -8-hydroxyquinoline derivatives against H(2)O(2)-induced oxidative stress in BMSCs.

Wang TT, Zeng GC, Li XC, Zeng HP.Chem Biol Drug Des. 2010 Feb;75(2):214-22. doi: 10.1111/j.1747-0285.2009.00925.x. Epub 2009 Dec 17.PMID: 20028394

The activity against lipid peroxidation was determined using ammonium thiocyanate method. The results revealed that introduction of electron-donating groups at 2nd position decreased the antioxidant activities of 8-hydroxyquinoline derivatives. …271Cite 

Antioxidant protection of eicosapentaenoic acid and fish oil oxidation by polyphenolic-enriched apple skin extract.

Rupasinghe HP, Erkan N, Yasmin A.J Agric Food Chem. 2010 Jan 27;58(2):1233-9. doi: 10.1021/jf903162k.PMID: 20000574

The ASE were effective in reducing the oxidation induced by heat, UV light and peroxyl radical, when the extent of oxidation of the emulsions and bulk oil was measured by using the ferric thiocyanate test, the thiobarbituric acid reactive substances assay and Rancimat. On …272Cite 

Redox thermodynamics of lactoperoxidase and eosinophil peroxidase.

Battistuzzi G, Bellei M, Vlasits J, Banerjee S, Furtmüller PG, Sola M, Obinger C.Arch Biochem Biophys. 2010 Feb 1;494(1):72-7. doi: 10.1016/j.abb.2009.11.021. Epub 2009 Nov 26.PMID: 19944669

These heme enzymes belong to the peroxidase-cyclooxygenase superfamily and catalyze the oxidation of thiocyanate, bromide and nitrite to hypothiocyanate, hypobromous acid and nitrogen dioxide that are toxic for invading pathogens. …Comparison with published data for myel …273Cite 

In situ solid state formation of copper(I) coordination polymers by thermal reduction of copper(II) precursor compounds: structure and reactivity of [Cu(NCS)2(pyrimidine)2]n.

Wriedt M, Näther C.Dalton Trans. 2009 Dec 14;(46):10192-8. doi: 10.1039/b909838k. Epub 2009 Aug 28.PMID: 19921053

Reaction of copper(II) thiocyanate with pyrimidine leads to the formation of the new ligand-rich 1:2 (1:2 = ratio metal salt to ligand) copper(II) compound [Cu(NCS)(2)(pyrimidine)(2)](n) (1). …274Cite 

Disulfides as cyanide antidotes: evidence for a new in vivo oxidative pathway for cyanide detoxification.

Zottola MA, Beigel K, Soni SD, Lawrence R.Chem Res Toxicol. 2009 Dec;22(12):1948-53. doi: 10.1021/tx900258m.PMID: 19891443

It is known that cyanide is converted to thiocyanate in the presence of the enzyme rhodanese. The enzyme is activated by sulfur transfer from an appropriate sulfur donor. …S-Methyl methylthiosulfonate (MTSO) was used to determine whether a mixed disulfide, if formed, wou …275Cite 

Comparison of the protective effects of steamed and cooked broccolis on ischaemia-reperfusion-induced cardiac injury.

Mukherjee S, Lekli I, Ray D, Gangopadhyay H, Raychaudhuri U, Das DK.Br J Nutr. 2010 Mar;103(6):815-23. doi: 10.1017/S0007114509992492. Epub 2009 Oct 27.PMID: 19857366

Recently, broccoli, a vegetable of the Brassica family, has been found to protect the myocardium from ischaemic reperfusion injury through the redox signalling of sulphoraphane, which is being formed from glucosinolate present in this vegetable. …The results of the prese …276Cite 

Extracellular redox status regulates Nrf2 activation through mitochondrial reactive oxygen species.

Imhoff BR, Hansen JM.Biochem J. 2009 Dec 10;424(3):491-500. doi: 10.1042/BJ20091286.PMID: 19778293

The redox status of the extracellular compartment has only just been elucidated as a mechanism controlling intracellular signal transduction and correlates with aging, diabetes, heart disease and lung fibrosis. …NIH 3T3 cells were cultured in medium with extracellular Cy …277Cite 

Screening and evaluation of antioxidant activity of some amido-carbonyl oxime derivatives and their radical scavenging activities.

Ozen T, Taş M.J Enzyme Inhib Med Chem. 2009 Oct;24(5):1141-7. doi: 10.1080/14756360802669981.PMID: 19772487 Free article.

The antioxidant activity of some amido-carbonyl oximes containing a C=O and -NH-R adjacent to the oxime group, [Phenyl-C(=O)-C(=N-OH)-N(-H)-Phenyl(-R)] where R= H, 4-chloro, 4-methyl, 4-methoxy, 3,4-dichloro, 3,4-dimethyl, 3-chloro-4-dimethyl, 3-chloro-4-methoxy, naphthyl and an …278Cite 

Investigation of antioxidant properties of Nasturtium officinale (watercress) leaf extracts.

Ozen T.Acta Pol Pharm. 2009 Mar-Apr;66(2):187-93.PMID: 19719054 Free article.

Extracts were evaluated for total antioxidant activity by ferric thiocyanate method, total reducing power by potassium ferricyanide reduction method, 1,1-diphenyl-2-picrylhydrazyl (DPPH*) radical scavenging activities, superoxide anion radical scavenging activities in vitr …279Cite 

Sulforaphane treatment protects skeletal muscle against damage induced by exhaustive exercise in rats.

Malaguti M, Angeloni C, Garatachea N, Baldini M, Leoncini E, Collado PS, Teti G, Falconi M, Gonzalez-Gallego J, Hrelia S.J Appl Physiol (1985). 2009 Oct;107(4):1028-36. doi: 10.1152/japplphysiol.00293.2009. Epub 2009 Aug 27.PMID: 19713431 Free article.

Our data demonstrate that SF acts as an indirect antioxidant in skeletal muscle and could play a critical role in the modulation of the muscle redox environment, leading to the prevention of exhaustive exercise-induced muscle damage….280Cite 

Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase.

Gandin V, Fernandes AP, Rigobello MP, Dani B, Sorrentino F, Tisato F, Björnstedt M, Bindoli A, Sturaro A, Rella R, Marzano C.Biochem Pharmacol. 2010 Jan 15;79(2):90-101. doi: 10.1016/j.bcp.2009.07.023. Epub 2009 Aug 7.PMID: 19665452

The inhibitory effect of the redox proteins was also observed intracellularly in cancer cells pretreated with gold(I) complexes. …In addition, they were able to activate caspase-3 and induce apoptosis observed as nucleosome formation and sub-G1 cell accumulation. The com …281Cite 

Thiohalobacter thiocyanaticus gen. nov., sp. nov., a moderately halophilic, sulfur-oxidizing gammaproteobacterium from hypersaline lakes, that utilizes thiocyanate.

Sorokin DY, Kovaleva OL, Tourova TP, Muyzer G.Int J Syst Evol Microbiol. 2010 Feb;60(Pt 2):444-450. doi: 10.1099/ijs.0.012880-0. Epub 2009 Aug 4.PMID: 19654366

The bacterium was an obligate aerobe capable of chemolithoautotrophic growth with thiocyanate and thiosulfate. With thiosulfate, it grew at NaCl concentrations of 0.2-3.0 M (optimum 0.5 M) and at pH 6.3-8.0 (optimum pH 7.3-7.5). During growth on thiocyanate, cyanate …282Cite 

Cysteine, thiourea and thiocyanate interactions with clays: FT-IR, Mossbauer and EPR spectroscopy and X-ray diffractometry studies.

de Santana H, Paesano A Jr, da Costa AC, di Mauro E, de Souza IG, Ivashita FF, de Souza CM, Zaia CT, Zaia DA.Amino Acids. 2010 Apr;38(4):1089-99. doi: 10.1007/s00726-009-0318-8. Epub 2009 Jul 5.PMID: 19579002

The present study examined the adsorption of cysteine, thiourea and thiocyanate on bentonite and montmorillonite at two different pHs (3.00, 8.00). The conditions used here are closer to those of prebiotic earth. …For the interaction of thiocyanate with the clays, …283Cite 

Peroxidative metabolism of beta2-agonists salbutamol and fenoterol and their analogues.

Reszka KJ, McGraw DW, Britigan BE.Chem Res Toxicol. 2009 Jun;22(6):1137-50. doi: 10.1021/tx900071f.PMID: 19462961 Free PMC article.

We show that in the presence of hydrogen peroxide, both myeloperoxidase, secreted by activated neutrophils present in inflamed airways, and lactoperoxidase, which is naturally present in the respiratory system, catalyze oxidation of these beta(2)-agonists. Azide, cyanide, thio …284Cite 

Synthesis and characterization of redox-active tris(pyrazolyl)borate cobalt complexes.

Harding DJ, Harding P, Daengngern R, Yimklan S, Adams H.Dalton Trans. 2009 Feb 28;(8):1314-20. doi: 10.1039/b815001j.PMID: 19462652

The reaction of [Tp(Ph2)CoBr] with NaX (X = N3, NO2) or potassium thiocyanate (KNCS) permits isolation of [Tp(Ph2)CoX] (X = N3 4, NCS 5, NO2 6). In contrast, the reaction of cobalt(II) acetate with KTp(Ph2) yields [Tp(Ph2)CO(OAc)(Hpz(Ph2))] 7 as a result of B-N bond cleava …285Cite 

Cellular responses to cancer chemopreventive agent D,L-sulforaphane in human prostate cancer cells are initiated by mitochondrial reactive oxygen species.

Xiao D, Powolny AA, Antosiewicz J, Hahm ER, Bommareddy A, Zeng Y, Desai D, Amin S, Herman-Antosiewicz A, Singh SV.Pharm Res. 2009 Jul;26(7):1729-38. doi: 10.1007/s11095-009-9883-5. Epub 2009 Apr 21.PMID: 19384467 Free PMC article.286Cite 

New paradigm in molecular engineering of sensitizers for solar cell applications.

Bessho T, Yoneda E, Yum JH, Guglielmi M, Tavernelli I, Imai H, Rothlisberger U, Nazeeruddin MK, Grätzel M.J Am Chem Soc. 2009 Apr 29;131(16):5930-4. doi: 10.1021/ja9002684.PMID: 19334729

A novel thiocyanate-free cyclometalleted ruthenium sensitizer for solar cells is designed and developed. …Molecular orbitals analysis confirmed the experimental assignment of redox potentials, and TDDFT calculations allowed assignment of the visible absorption ban …287Cite 

Antioxidant and antimicrobial activities of bitter and sweet apricot (Prunus armeniaca L.) kernels.

Yiğit D, Yiğit N, Mavi A.Braz J Med Biol Res. 2009 Apr;42(4):346-52. doi: 10.1590/s0100-879×2009000400006.PMID: 19330262 Free article.

The antioxidant properties of apricot kernels were evaluated by determining radical scavenging power, lipid peroxidation inhibition activity and total phenol content measured with a DPPH test, the thiocyanate method and the Folin method, respectively. In contrast to extrac …288Cite 

What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach.

Pattison DI, Hawkins CL, Davies MJ.Chem Res Toxicol. 2009 May;22(5):807-17. doi: 10.1021/tx800372d.PMID: 19326902

Ascorbate or alpha-tocopherol, even at the levels achieved in human supplementation studies, do not attenuate these reactions. In contrast, elevated levels of thiocyanate ions (SCN(-)), as detected in heavy smokers, can modulate HOCl-mediated reactions as a result of the f …289Cite 

Analysis of 7,8-dihydro-8-oxo-2′-deoxyguanosine in cellular DNA during oxidative stress.

Mangal D, Vudathala D, Park JH, Lee SH, Penning TM, Blair IA.Chem Res Toxicol. 2009 May;22(5):788-97. doi: 10.1021/tx800343c.PMID: 19309085 Free PMC article.

Cellular DNA was isolated using cold DNAzol (a proprietary product that contains guanidine thiocyanate) instead of chaotropic- or phenol-based methodology. Chelex-treated buffers were used to prevent Fenton chemistry-mediated generation of reactive oxygen species (ROS) and …290Cite 

Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents.

Higgins LG, Kelleher MO, Eggleston IM, Itoh K, Yamamoto M, Hayes JD.Toxicol Appl Pharmacol. 2009 Jun 15;237(3):267-80. doi: 10.1016/j.taap.2009.03.005. Epub 2009 Mar 20.PMID: 19303893

Sulforaphane can stimulate cellular adaptation to redox stressors through transcription factor Nrf2. Using mouse embryonic fibroblasts (MEFs) as a model, we show herein that the normal homeostatic level of glutathione in Nrf2(-/-) MEFs was only 20% of that in their wild-ty …291Cite 

[Kinetics study on reaction of chlorine dioxide and thiocyanide in water].

Hu C, Bi X, Zhang L, Li H.Wei Sheng Yan Jiu. 2009 Jan;38(1):22-3, 35.PMID: 19267068 Chinese.292Cite 

Necessity of fine tuning in Mo(iv) bis(dithiolene) complexes to warrant nitrate reduction.

Majumdar A, Pal K, Sarkar S.Dalton Trans. 2009 Mar 21;(11):1927-38. doi: 10.1039/b815436h. Epub 2009 Jan 28.PMID: 19259562

Complexes , and can be converted to or depending on the amount of thiocyanate employed. Complexes and undergo a facile interconversion among themselves. Substitution of essential thiolate coordination rather than replacing the dissociable PPh(3) in and by thiocyanate …293Cite 

Free radical scavenging and lipid peroxidation activity of the Shahani black grape.

Yassa N, Beni HR, Hadjiakhoondi A.Pak J Biol Sci. 2008 Nov 1;11(21):2513-6. doi: 10.3923/pjbs.2008.2513.2516.PMID: 19205274

The antioxidant activity of grape berry juice, seed and skin extracts were measured by the inhibition of lipid peroxidation (Ferric Ammonium Thiocyanate) and free radical scavenging activity (2, 2-diphenyl-l-picrylhydrazyl) methods. …294Cite 

Correlation between the stability and redox potential of three homologous cytochromes c from two thermophiles and one mesophile.

Takeda T, Sonoyama T, Takayama SJ, Mita H, Yamamoto Y, Sambongi Y.Biosci Biotechnol Biochem. 2009 Feb;73(2):366-71. doi: 10.1271/bbb.80607. Epub 2009 Feb 7.PMID: 19202290 Free article.

The stability of the oxidized and reduced forms of three homologous cytochromes c from two thermophiles and one mesophile was systematically monitored by means of Soret absorption measurements in the presence of various concentrations of a denaturant, guanidine thiocyanate …295Cite 

First stable reduced form of [Co(5)](+10): fine tuning of linear pentacobalt(ii) complexes containing delocalized metal-metal bonds through ligand modification.

Wang WZ, Ismayilov RH, Wang RR, Huang YL, Yeh CY, Lee GH, Peng SM.Dalton Trans. 2008 Dec 21;(47):6808-16. doi: 10.1039/b811520f. Epub 2008 Oct 22.PMID: 19153628

Electrochemical studies on both and showed one reversible oxidation and one reversible reduction at E(1/2) = +0.82 and -0.05 V for , and at E(1/2) = +0.89 and +0.02 V for , respectively. The redox reactions of the thiocyanate complex happened at higher potentials th …296Cite 

Effect of broccoli (Brassica oleracea) and its phytochemical sulforaphane in balanced diets on the detoxification enzymes levels of tilapia (Oreochromis niloticus) exposed to a carcinogenic and mutagenic pollutant.

Villa-Cruz V, Davila J, Viana MT, Vazquez-Duhalt R.Chemosphere. 2009 Mar;74(9):1145-51. doi: 10.1016/j.chemosphere.2008.11.082. Epub 2009 Jan 13.PMID: 19144376297Cite 

Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures.

Siebert A, Desai V, Chandrasekaran K, Fiskum G, Jafri MS.J Neurosci Res. 2009 May 15;87(7):1659-69. doi: 10.1002/jnr.21975.PMID: 19125416

Once activated, these genes work synergistically to maintain intracellular redox homeostasis. In this study, we test the hypothesis that Nrf2 activation can protect dopaminergic neurons against 6-hydroxydopamine (6-OHDA)-induced toxicity. …298Cite 

Molecular mechanisms underlying cochlear degeneration in the tubby mouse and the therapeutic effect of sulforaphane.

Kong L, Chen GD, Zhou X, McGinnis JF, Li F, Cao W.Neurochem Int. 2009 Mar-Apr;54(3-4):172-9. doi: 10.1016/j.neuint.2008.08.013. Epub 2008 Dec 9.PMID: 19114066 Free PMC article.

Yet, the mechanism underlying the tub-related cochlear degeneration is still unclear. The reduction/oxidation (redox) imbalance in the cell is related to many kinds of diseases. This study examined expressions of thioredoxin (Trx) and Trx reductase (TrxR), an important …299Cite 

Antioxidant and antiinflammatory activity of pine pollen extract in vitro.

Lee KH, Kim AJ, Choi EM.Phytother Res. 2009 Jan;23(1):41-8. doi: 10.1002/ptr.2525.PMID: 19107823

It was observed also that the antioxidant activity, measured by the ferric thiocyanate method, increased with the addition of PPE to the linoleic acid emulsion system. …300Cite 

Electrocatalytic behaviour of carbon paste electrode modified with iron(II) phthalocyanine (FePc) nanoparticles towards the detection of amitrole.

Siswana M, Ozoemena KI, Nyokong T.Talanta. 2006 Jul 15;69(5):1136-42. doi: 10.1016/j.talanta.2005.12.014. Epub 2006 Jan 10.PMID: 18970694

The mechanism for the interaction of amitrole with the nanoFePc is proposed to involve the Fe((III))Pc/Fe((II))Pc redox process. Using chronoamperometry (E=+0.42V versus Ag/AgCl) technique, the sensor was reliably employed for amitrole assay at pH 12.0 phosphate buffer (wi …301Cite 

Catalytic spectrophotometric determination of tungsten using the malachite green-Ti(III) redox reaction and a thiocyanate activator.

Pourreza N, Mohammadi-Sedehi I.Talanta. 2002 Mar 4;56(3):435-9. doi: 10.1016/s0039-9140(01)00566-5.PMID: 18968515

Thiocyanate was found to have a highly activating effect on the tungsten-catalyzed reaction of malachite green with Ti(III). …302Cite 

Reactive sulfur species: kinetics and mechanism of the reaction of thiocarbamate-S-oxide with cysteine.

Wang X, Ashby MT.Chem Res Toxicol. 2008 Nov;21(11):2120-6. doi: 10.1021/tx800195n.PMID: 18942795

Hypothiocyanite decomposes via an unknown mechanism that involves multiple redox and hydrolytic steps to eventually yield mixtures of CN(-)/OCN(-) and SO(3)(2-)/SO(4)(2-). …303Cite 

Interaction between ascorbic acid and chlorogenic acid during the formation of nitric oxide in acidified saliva.

Takahama U, Tanaka M, Hirota S.J Agric Food Chem. 2008 Nov 12;56(21):10406-13. doi: 10.1021/jf8018535. Epub 2008 Oct 16.PMID: 18922016

The NO formation in acidified saliva was enhanced by ascorbic acid and chlorogenic acid. Thiocyanate ion (SCN(-)) also enhanced the transformation of nitrous acid to NO. During the NO formation in the presence of both ascorbic acid and chlorogenic acid, ascorbic acid was p …304Cite 

In vitro antioxidant activity of silymarin.

Köksal E, Gülçin I, Beyza S, Sarikaya O, Bursal E.J Enzyme Inhib Med Chem. 2009 Apr;24(2):395-405. doi: 10.1080/14756360802188081.PMID: 18830883 Free article.

In the present paper, we clarified the antioxidant activity of silymarin by employing various in vitro antioxidant assay such as 1,1-diphenyl-2-picryl-hydrazyl free radical (DPPH(.)) scavenging, 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activ …305Cite 

The Pseudomonas toxin pyocyanin inhibits the dual oxidase-based antimicrobial system as it imposes oxidative stress on airway epithelial cells.

Rada B, Lekstrom K, Damian S, Dupuy C, Leto TL.J Immunol. 2008 Oct 1;181(7):4883-93. doi: 10.4049/jimmunol.181.7.4883.PMID: 18802092 Free PMC article.

The dual oxidase-thiocyanate-lactoperoxidase (Duox/SCN(-)/LPO) system generates the microbicidal oxidant hypothiocyanite in the airway surface liquid by using LPO, thiocyanate, and Duox-derived hydrogen peroxide released from the apical surface of the airway epithel …306Cite 

Effect of humic substances on the Fenton treatment of wastewater at acidic and neutral pH.

Lipczynska-Kochany E, Kochany J.Chemosphere. 2008 Oct;73(5):745-50. doi: 10.1016/j.chemosphere.2008.06.028.PMID: 18657846

At pH 3.5, humate had no effect on the removal of arsenic, thiocyanate and cyanide, but the removal of all organic compounds (phenol, 2,4-dimethylphenol, benzene, toluene, o-xylene, m- & p-xylene and dichloromethane) was significantly inhibited. …307Cite 

Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation.

Hawkins CL, Pattison DI, Stanley NR, Davies MJ.Biochem J. 2008 Dec 15;416(3):441-52. doi: 10.1042/BJ20070941.PMID: 18652572

With albumin, thiols are oxidized preferentially forming unstable sulfenyl thiocyanate derivatives, as evidenced by the reversible incorporation of (14)C from HOS(14)CN. …308Cite 

Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal cell death.

Rojo AI, Rada P, Egea J, Rosa AO, López MG, Cuadrado A.Mol Cell Neurosci. 2008 Sep;39(1):125-32. doi: 10.1016/j.mcn.2008.06.007. Epub 2008 Jun 20.PMID: 18619545

Considering that oxidative stress is central to excitotoxic damage, in this study we sought to analyze if the transcription factor Nrf2, guardian of redox homeostasis, might be targeted to prevent kainate-induced neuron death. Hippocampal slices from Nrf2 knockout mice exh …309Cite 

Controllable redox reaction of chemically purified DNA-single walled carbon nanotube hybrids with hydrogen peroxide.

Xu Y, Pehrsson PE, Chen L, Zhao W.J Am Chem Soc. 2008 Aug 6;130(31):10054-5. doi: 10.1021/ja802743h. Epub 2008 Jul 9.PMID: 18611008

We report for the first time the controllable redox reaction of chemically purified ssDNA-HiPco SWNT hybrids with hydrogen peroxide. …The tunable redox reaction of SWNTs and H2O2 mediated by thiocyanate ions may offer a new sensing scheme for continuously m …310Cite 

High-performance dye-sensitized solar cells based on solvent-free electrolytes produced from eutectic melts.

Bai Y, Cao Y, Zhang J, Wang M, Li R, Wang P, Zakeeruddin SM, Grätzel M.Nat Mater. 2008 Aug;7(8):626-30. doi: 10.1038/nmat2224. Epub 2008 Jun 29.PMID: 18587401

Solvent-free room-temperature ionic liquids have been pursued as an attractive solution to this dilemma, and device efficiencies of over 7% were achieved by using some low-viscosity formulations containing 1-ethyl-3-methylimidazolium thiocyanate, selenocyanate, tricyanomet …311Cite 

The transcription factor Nrf2 is a therapeutic target against brain inflammation.

Innamorato NG, Rojo AI, García-Yagüe AJ, Yamamoto M, de Ceballos ML, Cuadrado A.J Immunol. 2008 Jul 1;181(1):680-9. doi: 10.4049/jimmunol.181.1.680.PMID: 18566435 Free article.

In this study, we identify the transcription factor Nrf2, guardian of redox homeostasis, as such target in a model of LPS-induced inflammation in mouse hippocampus. …The aliphatic isothiocyanate sulforaphane elicited an Nrf2-mediated antioxidant response in the BV2 micro …312Cite 

Reduction of nitrous Acid to nitric oxide by coffee melanoidins and enhancement of the reduction by thiocyanate: possibility of its occurrence in the stomach.

Takahama U, Hirota S.J Agric Food Chem. 2008 Jun 25;56(12):4736-44. doi: 10.1021/jf703660k. Epub 2008 Jun 4.PMID: 18522412

Reactions of nitrous acid with freeze-dried instant coffee and its methanol-insoluble melanoidin fractions were studied at pH 2 in the presence and absence of thiocyanate (SCN (-)), simulating the mixture of coffee, saliva, and gastric juice. Coffee contained stable radica …313Cite 

Aurocyanide, dicyano-aurate (I), a pharmacologically active metabolite of medicinal gold complexes.

Graham GG, Whitehouse MW, Bushell GR.Inflammopharmacology. 2008 Jun;16(3):126-32. doi: 10.1007/s10787-007-0020-y.PMID: 18521543

Au(CN) (2) (-) is generated from the therapeutic gold complexes by small amounts of hydrogen cyanide, HCN, produced from thiocyanate, SCN(-), by myeloperoxidase (MPO) an enzyme in neutrophils which normally produces hypochlorite, OCl(-). …Au(CN) (2) (-) may also be invol …314Cite 

Demonstration by redox fluorometry that sulforaphane protects retinal pigment epithelial cells against oxidative stress.

del V Cano M, Reyes JM, Park CY, Gao X, Mori K, Chuck RS, Gehlbach PL.Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2606-12. doi: 10.1167/iovs.07-0960.PMID: 18515589

The ratio of these measurements served as the index of cellular redox status. RESULTS: Redox ratio and cell viability decreased in a dose-dependent manner after oxidant exposure. …Similar results were observed after insult with tert-butyl hydroperoxide. CONCLUSION …315Cite 

Trace level determination of molybdenum in environmental and biological samples using surfactant-mediated liquid-liquid extraction.

Shrivas K, Agrawal K, Harmukh N.J Hazard Mater. 2009 Jan 15;161(1):325-9. doi: 10.1016/j.jhazmat.2008.03.092. Epub 2008 Mar 27.PMID: 18462870

The method is based on the reaction of Mo (V) with thiocyanate (SCN(-)) and methyltrioctyl ammonium chloride (MTOAC) in acidic medium. The red colored complex of molybdenum is extracted with N-phenylbenzimidoyl thiourea (PBITU) in 1-pentanol for its determination by spectr …316Cite 

Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid.

Lloyd MM, van Reyk DM, Davies MJ, Hawkins CL.Biochem J. 2008 Sep 1;414(2):271-80. doi: 10.1042/BJ20080468.PMID: 18459943

This induction of damage by HOSCN may be of critical importance in people with elevated levels of SCN(-) (thiocyanate ions) arising from cigarette smoking, and plays a role in the pathologies associated with this biological insult….317Cite 

Direct and indirect antioxidant properties of inducers of cytoprotective proteins.

Dinkova-Kostova AT, Talalay P.Mol Nutr Food Res. 2008 Jun;52 Suppl 1:S128-38. doi: 10.1002/mnfr.200700195.PMID: 18327872 Review.

Cellular protection against oxidative and electrophile toxicities is provided by two types of small-molecule antioxidants: (i) direct antioxidants, which are redox active, short-lived, are sacrificed in the process of their antioxidant actions and need to be replenished or …318Cite 

Nrf2 activation by sulforaphane restores the age-related decrease of T(H)1 immunity: role of dendritic cells.

Kim HJ, Barajas B, Wang M, Nel AE.J Allergy Clin Immunol. 2008 May;121(5):1255-1261.e7. doi: 10.1016/j.jaci.2008.01.016. Epub 2008 Mar 5.PMID: 18325578 Free PMC article.

OBJECTIVES: We sought (1) to elucidate the role of DC redox equilibrium in the decrease of contact hypersensitivity (CHS) and T(H)1 immunity during aging and (2) to determine how restoration of glutathione (GSH) levels by the Nrf2-mediated antioxidant defense pathway affec …319Cite 

Synthesis of dimeric phenol derivatives and determination of in vitro antioxidant and radical scavenging activities.

Güllçin I, Daştan A.J Enzyme Inhib Med Chem. 2007 Dec;22(6):685-95. doi: 10.1080/14756360601164903.PMID: 18237020 Free article.

Their antioxidant capacity and radical scavenging activity were examined using different in vitro methodologies such as 1,1-diphenyl-2-picryl-hydrazyl (DPPH*) free radical scavenging, 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, total …320Cite 

Modification of IkappaBalpha by taurine bromamine inhibits tumor necrosis factor alpha-induced NF-kappaB activation.

Tokunaga S, Kanayama A, Miyamoto Y.Inflamm Res. 2007 Nov;56(11):479-86. doi: 10.1007/s00011-007-7016-3.PMID: 18224289321Cite 

Thiocyanate hydrolase, the primary enzyme initiating thiocyanate degradation in the novel obligately chemolithoautotrophic halophilic sulfur-oxidizing bacterium Thiohalophilus thiocyanoxidans.

Bezsudnova EY, Sorokin DY, Tikhonova TV, Popov VO.Biochim Biophys Acta. 2007 Dec;1774(12):1563-70. doi: 10.1016/j.bbapap.2007.09.003. Epub 2007 Sep 21.PMID: 17964868

Thiohalophilus thiocyanoxidans is a first halophilic sulfur-oxidizing chemolithoautotrophic bacterium capable of growth with thiocyanate as an electron donor at salinity up to 4 M NaCl. The cells, grown with thiocyanate, but not with thiosulfate, contained an enzyme …322Cite 

Dual-function of thiocyanate on nitrite-induced formation of reactive nitrogen oxide species in human oral cavity: inhibition under neutral and enhancement under acidic conditions.

Takahama U, Ryu K, Oniki T, Hirota S.Free Radic Res. 2007 Nov;41(11):1289-300. doi: 10.1080/10715760701710885.PMID: 17957543323Cite 

‘Multipurpose oxidase’ in atherogenesis.

Rader DJ, Ischiropoulos H.Nat Med. 2007 Oct;13(10):1146-7. doi: 10.1038/nm1007-1146b.PMID: 17917660 No abstract available.324Cite 

Protein carbamylation links inflammation, smoking, uremia and atherogenesis.

Wang Z, Nicholls SJ, Rodriguez ER, Kummu O, Hörkkö S, Barnard J, Reynolds WF, Topol EJ, DiDonato JA, Hazen SL.Nat Med. 2007 Oct;13(10):1176-84. doi: 10.1038/nm1637. Epub 2007 Sep 9.PMID: 17828273

We now report the discovery of an alternative and quantitatively dominant mechanism for cyanate formation and protein carbamylation at sites of inflammation and atherosclerotic plaque: myeloperoxidase-catalyzed oxidation of thiocyanate, an anion abundant in blood whose lev …325Cite 

Synthesis of positively charged silver nanoparticles via photoreduction of AgNO3 in branched polyethyleneimine/HEPES solutions.

Tan S, Erol M, Attygalle A, Du H, Sukhishvili S.Langmuir. 2007 Sep 11;23(19):9836-43. doi: 10.1021/la701236v. Epub 2007 Aug 17.PMID: 17705409

Importantly, these positively charged Ag nanoparticles demonstrate superior SERS activity over negatively charged citrate reduced Ag nanoparticles for the detection of thiocyanate and perchlorate ions; therefore, they are promising candidates for sensing and detection of a …326Cite 

Thiohalomonas denitrificans gen. nov., sp. nov. and Thiohalomonas nitratireducens sp. nov., novel obligately chemolithoautotrophic, moderately halophilic, thiodenitrifying Gammaproteobacteria from hypersaline habitats.

Sorokin DY, Tourova TP, Braker G, Muyzer G.Int J Syst Evol Microbiol. 2007 Jul;57(Pt 7):1582-1589. doi: 10.1099/ijs.0.65112-0.PMID: 17625198

A single strain, HRhD 3sp(T), with vibrio-shaped cells, was obtained from a co-culture capable of complete denitrification of nitrate in the presence of either thiocyanate or thiosulfate as electron donor. It grew anaerobically with thiosulfate, reducing nitrate to nitrite …327Cite 

Reactions of thiocyanate in the mixture of nitrite and hydrogen peroxide under acidic conditions: investigation of the reactions simulating the mixture of saliva and gastric juice.

Takahama U, Tanaka M, Oniki T, Hirota S.Free Radic Res. 2007 Jun;41(6):627-37. doi: 10.1080/10715760701218566.PMID: 17516234328Cite 

Disruption of the aspartate to heme ester linkage in human myeloperoxidase: impact on ligand binding, redox chemistry, and interconversion of redox intermediates.

Zederbauer M, Furtmüller PG, Bellei M, Stampler J, Jakopitsch C, Battistuzzi G, Moguilevsky N, Obinger C.J Biol Chem. 2007 Jun 8;282(23):17041-52. doi: 10.1074/jbc.M610685200. Epub 2007 Apr 16.PMID: 17438335 Free article.

By contrast, in both variants rates of compound I reduction by chloride and bromide (but not iodide and thiocyanate) were substantially decreased compared with the wild-type protein. Bimolecular rates of compound II (but not compound I) reduction by ascorbate and tyrosine …329Cite 

Antioxidant and protective effect of an oleanolic acid-enriched extract of A. deliciosa root on carbon tetrachloride induced rat liver injury.

Bai X, Qiu A, Guan J, Shi Z.Asia Pac J Clin Nutr. 2007;16 Suppl 1:169-73.PMID: 17392098 Free article.

The antioxidant and hepatoprotective activities of various EEAD fractions and OLA were carefully investigated by the methods of ferric thiocyanate (FTC) and thiobarbituric acid (TBA), as well as the model of CCL4-induced liver toxicity in rats. …330Cite 

The vinyl-sulfonium bond in human myeloperoxidase: impact on compound I formation and reduction by halides and thiocyanate.

Zederbauer M, Furtmüller PG, Ganster B, Moguilevsky N, Obinger C.Biochem Biophys Res Commun. 2007 May 4;356(2):450-6. doi: 10.1016/j.bbrc.2007.02.157. Epub 2007 Mar 8.PMID: 17359937

Compared with wild-type recombinant MPO the cyanide association rate with ferric Met243Val was significantly enhanced as were also the calculated apparent bimolecular compound I reduction rates by iodide (>10(8) M(-1)s(-1)) and thiocyanate (>10(8) M(-1)s(-1)). By con …331Cite 

Chemolithoautotrophic oxidation of thiosulfate, tetrathionate and thiocyanate by a novel rhizobacterium belonging to the genus Paracoccus.

Ghosh W, Roy P.FEMS Microbiol Lett. 2007 May;270(1):124-31. doi: 10.1111/j.1574-6968.2007.00670.x. Epub 2007 Feb 26.PMID: 17326754

While SST had versatile chemolithotrophic abilities to oxidize thiosulfate, tetrathionate, thiocyanate, sulfide and elemental sulfur, JT 001 could oxidize thiosulfate, soluble sulfide, elemental sulfur and a relatively lesser amount of tetrathionate. …332Cite 

Dual action of sulforaphane in the regulation of thioredoxin reductase and thioredoxin in human HepG2 and Caco-2 cells.

Bacon JR, Plumb GW, Howie AF, Beckett GJ, Wang W, Bao Y.J Agric Food Chem. 2007 Feb 21;55(4):1170-6. doi: 10.1021/jf062398+.PMID: 17300148

In summary, the dietary isothiocyanate, sulforaphane, is important in the regulation of thioredoxin reductase/thioredoxin redox system in cells….333Cite 

Synthesis, characterization, and biomimetic chemistry of cis-oxosulfidomolybdenum(VI) complexes stabilized by an intramolecular Mo(O)=S…S interaction.

Laughlin LJ, Eagle AA, George GN, Tiekink ER, Young CG.Inorg Chem. 2007 Feb 5;46(3):939-48. doi: 10.1021/ic061213d.PMID: 17257038

The complexes react with excess cyanide to form thiocyanate and Tp*MoO(S2PR2), under anaerobic conditions, or Tp*MoO2(S2PR2), under aerobic conditions; the latter models the production of thiocyanate and desulfo molybdenum hydroxylases upon cyanolysis of molybdenum …334Cite 

Saliva plays a dual role in oxidation process in stomach medium.

Gorelik S, Kohen R, Ligumsky M, Kanner J.Arch Biochem Biophys. 2007 Feb 15;458(2):236-43. doi: 10.1016/j.abb.2006.12.006. Epub 2006 Dec 12.PMID: 17250799

The pseudoperoxidase activity of lactoperoxidase increased lipid peroxidation, while thiocyanate and nitrite-reduced lipid peroxidation. The effect of a saliva specimen on lipid peroxidation was correlated with the concentration of nitrite in the specimen, but not with tha …335Cite 

Determination of antioxidant and radical scavenging activity of Basil (Ocimum basilicum L. Family Lamiaceae) assayed by different methodologies.

Gülçin I, Elmastaş M, Aboul-Enein HY.Phytother Res. 2007 Apr;21(4):354-61. doi: 10.1002/ptr.2069.PMID: 17221941

In the present study, the possible radical scavenging and antioxidant activity of the water (WEB) and ethanol extracts (EEB) of basil was investigated using different antioxidant methodologies: 1,1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging, scavenging of superoxid …336Cite 

Denitrification in a binary culture and thiocyanate metabolism in Thiohalophilus thiocyanoxidans gen. nov. sp. nov. – a moderately halophilic chemolithoautotrophic sulfur-oxidizing Gammaproteobacterium from hypersaline lakes.

Sorokin DY, Tourova TP, Bezsoudnova EY, Pol A, Muyzer G.Arch Microbiol. 2007 Jun;187(6):441-50. doi: 10.1007/s00203-006-0208-3. Epub 2007 Jan 10.PMID: 17216167

As well as thiosulfate, strain HRhD 2 can also use thiocyanate as electron donor, representing a first halophilic SOB capable of growth with thiocyanate at 2-4 M NaCl. Product and enzymatic analysis identified the “carbonyl sulfide (COS) pathway” of primary thioc …337Cite 

NADH screen-printed electrodes modified with zirconium phosphate, Meldola blue, and Reinecke salt. Application to the detection of glycerol by FIA.

Radoi A, Compagnone D, Batic M, Klincar J, Gorton L, Palleschi G.Anal Bioanal Chem. 2007 Feb;387(3):1049-58. doi: 10.1007/s00216-006-0975-3. Epub 2007 Jan 4.PMID: 17203252338Cite 

Molecular engineering of organic sensitizers for solar cell applications.

Kim S, Lee JK, Kang SO, Ko J, Yum JH, Fantacci S, De Angelis F, Di Censo D, Nazeeruddin MK, Grätzel M.J Am Chem Soc. 2006 Dec 27;128(51):16701-7. doi: 10.1021/ja066376f.PMID: 17177420

The photovoltaic data using an electrolyte having composition of 0.6 M M-methyl-N-butyl imidiazolium iodide, 0.04 M iodine, 0.025 M LiI, 0.05 M guanidinium thiocyanate, and 0.28 M tert-butylpyridine in a 15/85 (v/v) mixture of valeronitrile and acetonitrile revealed a shor …339Cite 

Selenium and sulforaphane modify the expression of selenoenzymes in the human endothelial cell line EAhy926 and protect cells from oxidative damage.

Campbell L, Howie F, Arthur JR, Nicol F, Beckett G.Nutrition. 2007 Feb;23(2):138-44. doi: 10.1016/j.nut.2006.10.006. Epub 2006 Dec 5.PMID: 17150329340Cite 

Effect of thiocyanate on the peroxidase and pseudocatalase activities of Leishmania major ascorbate peroxidase.

Dolai S, Yadav RK, Datta AK, Adak S.Biochim Biophys Acta. 2007 Feb;1770(2):247-56. doi: 10.1016/j.bbagen.2006.10.001. Epub 2006 Oct 5.PMID: 17118560341Cite 

A novel volumetric method for quantitation of titanium dioxide in cosmetics.

Kim YS, Kim BM, Park SC, Jeong HJ, Chang IS.J Cosmet Sci. 2006 Sep-Oct;57(5):377-83.PMID: 17111072

In this research, we analyzed the amounts of titanium dioxide in sunscreen cosmetics by adapting redox titration, reduction of Ti(IV) to Ti(III), and reoxidation to Ti(IV). After calcification of other organic ingredients of cosmetics, titanium dioxide is dissolved by hot …342Cite 

Antioxidant activity of Viscum album ssp. album.

Onay-Uçar E, Karagöz A, Arda N.Fitoterapia. 2006 Dec;77(7-8):556-60. doi: 10.1016/j.fitote.2006.08.001. Epub 2006 Sep 22.PMID: 17056203

Scavenging activity was tested by 1,1-diphenyl-2-picrylhydrazyl (DPPH) method and the inhibitory effect on lipid peroxidation was examined by ferric thiocyanate and thiobarbituric acid methods. The extract from mistletoe grown on lime tree in summer showed the highest acti …343Cite 

Lactoperoxidase-catalyzed oxidation of thiocyanate by hydrogen peroxide: a reinvestigation of hypothiocyanite by nuclear magnetic resonance and optical spectroscopy.

Nagy P, Alguindigue SS, Ashby MT.Biochemistry. 2006 Oct 17;45(41):12610-6. doi: 10.1021/bi061015y.PMID: 17029415344Cite 

Diversity of culturable halophilic sulfur-oxidizing bacteria in hypersaline habitats.

Sorokin DY, Tourova TP, Lysenko AM, Muyzer G.Microbiology (Reading). 2006 Oct;152(Pt 10):3013-3023. doi: 10.1099/mic.0.29106-0.PMID: 17005982 Free article.

The group represents a new genus with closest relatives among as yet undescribed marine thiodenitrifying isolates. With thiocyanate as a substrate, an enrichment culture at 2 M NaCl yielded a pure culture of moderately halophilic SOB capable of aerobic growth with thioc …345Cite 

A new model of cystic fibrosis pathology: lack of transport of glutathione and its thiocyanate conjugates.

Childers M, Eckel G, Himmel A, Caldwell J.Med Hypotheses. 2007;68(1):101-12. doi: 10.1016/j.mehy.2006.06.020. Epub 2006 Aug 24.PMID: 16934416

These alterations in normal cellular GSH levels affect the redox state of the cell, thereby affecting the intracellular stress protein, metallothionein. The authors describe how this disruption of the redox state caused by excess cellular GSH, will naturally prevent …346Cite 

Thiocyanate cannot inhibit the formation of reactive nitrogen species in the human oral cavity in the presence of high concentrations of nitrite: detection of reactive nitrogen species with 4,5-diaminofluorescein.

Takahama U, Hirota S, Oniki T.Chem Res Toxicol. 2006 Aug;19(8):1066-73. doi: 10.1021/tx060038a.PMID: 16918246347Cite 

The effect of ethanol extract of Hypericum lysimachioides on lipid profile in hypercholesterolemic rabbits and its in vitro antioxidant activity.

Hakimoğlu F, Kizil G, Kanay Z, Kizil M, Isi H.Atherosclerosis. 2007 May;192(1):113-22. doi: 10.1016/j.atherosclerosis.2006.07.013. Epub 2006 Aug 9.PMID: 16901489

Total antioxidant activity of ethanol extract of HL was tested by using ferric thiocyanate (FTC) and thiobarbituric acid (TBA) methods. Antioxidative activities of ethanol extract of HL was found to be comparable with Vitamin E. …348Cite 

Dye-sensitized SnO2 electrodes with iodide and pseudohalide redox mediators.

Bergeron BV, Marton A, Oskam G, Meyer GJ.J Phys Chem B. 2005 Jan 20;109(2):937-43. doi: 10.1021/jp0461347.PMID: 16866462

Dye-sensitized mesoporous nanocrystalline SnO2 electrodes and the pseudohalogen redox mediator (SeCN)2/SeCN- or (SCN)2/SCN- or the halogen redox mediator I3-/I- were implemented for regenerative solar cell studies. …349Cite 

Reactivity of DNA guanyl radicals with phenolate anions.

Ly A, Bandong SL, Tran NQ, Sullivan KJ, Milligan JR.J Phys Chem B. 2005 Jul 14;109(27):13368-74. doi: 10.1021/jp050495k.PMID: 16852669

Electron-deficient guanine species are major intermediates produced in DNA by the direct effect of ionizing radiation (ionization of the DNA itself) because of preferential hole migration within DNA to guanine bases. By using thiocyanate ions to modify the indirect effect …350Cite 

Photophysical and (photo)electrochemical properties of a coumarin dye.

Wang ZS, Hara K, Dan-oh Y, Kasada C, Shinpo A, Suga S, Arakawa H, Sugihara H.J Phys Chem B. 2005 Mar 10;109(9):3907-14. doi: 10.1021/jp044851v.PMID: 16851443

The sandwich-type solar cell with NKX-2753, under illumination of full sun (AM1.5, 100 mW cm(-2)), produced 16.1 mA cm(-2) of short-circuit photocurrent, 0.60 V of open-circuit photovoltage, and 0.69 of fill factor, corresponding to 6.7% of overall energy conversion efficiency us …351Cite 

Sensitive spectrophotometric methods for quantitative determination of chlorprothixene in pharmaceutical dosage form.

Misiuk W.Pak J Pharm Sci. 2006 Apr;19(2):87-94.PMID: 16751116

The second method involves the formation of ion-pair between the drug under investigation and inorganic complexes of titanium (IV) thiocyanate followed by its extraction with mixture of butanol-chloroform (1:9, v/v). The optimum conditions for the oxidation of CPT or ion-p …352Cite 

Nitrate-dependent [Fe(II)EDTA]2- oxidation by Paracoccus ferrooxidans sp. nov., isolated from a denitrifying bioreactor.

Kumaraswamy R, Sjollema K, Kuenen G, van Loosdrecht M, Muyzer G.Syst Appl Microbiol. 2006 Jun;29(4):276-86. doi: 10.1016/j.syapm.2005.08.001. Epub 2005 Sep 1.PMID: 16682296

Apart from [Fe(II)EDTA]2-, BDN-1 could also use thiosulfate and thiocyanate as inorganic electron donors. Nitrate, nitrite, N2O, [Fe(II)EDTA.NO]2- and oxygen could be used by strain BDN-1 as electron acceptors. …353Cite 

Screening of antiradical and antioxidant activity of monodesmosides and crude extract from Leontice smirnowii tuber.

Gülçin I, Mshvildadze V, Gepdiremen A, Elias R.Phytomedicine. 2006 May;13(5):343-51. doi: 10.1016/j.phymed.2005.03.009. Epub 2005 Sep 16.PMID: 16635742

In the current study we investigated the possible antiradical and antioxidant activity of the monodesmosides (MLS) and crude extract (CELS) of Leontice smirnowii using different antioxidant tests: 1,1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging, scavenging of supero …354Cite 

Optimization of the components concentrations of the lactoperoxidase system by RSM.

Adolphe Y, Jacquot M, Linder M, Revol-Junelles AM, Millière JB.J Appl Microbiol. 2006 May;100(5):1034-42. doi: 10.1111/j.1365-2672.2006.02892.x.PMID: 16630004

METHODS AND RESULTS: Experimental design using RSM was used for modelling effects and interactions of GOD (28.5-142.5 IU l(-1)), glucose (0.55-11.11 mmol l(-1)), LPO (0-6284 IU l(-1)) concentrations, and pH-values (6.0-7.4) on thiocyanate peroxidation. A fixed SCN- concent …355Cite 

Is the hypothiocyanite anion (OSCN)- the major product in the peroxidase catalyzed oxidation of the thiocyanate anion (SCN)-? A joint experimental and theoretical study.

Dua S, Maclean MJ, Fitzgerald M, McAnoy AM, Bowie JH.J Phys Chem A. 2006 Apr 13;110(14):4930-6. doi: 10.1021/jp058144t.PMID: 16599464356Cite 

Quercetin-dependent scavenging of reactive nitrogen species derived from nitric oxide and nitrite in the human oral cavity: interaction of quercetin with salivary redox components.

Takahama U, Hirota S, Oniki T.Arch Oral Biol. 2006 Aug;51(8):629-39. doi: 10.1016/j.archoralbio.2006.02.011. Epub 2006 Apr 3.PMID: 16581012

Nitrite-induced fluorescence increase was also observed in the saliva which contained salivary redox components. Quercetin effectively inhibited the fluorescence increase. During the inhibition of the fluorescence increases by quercetin, the flavonol was oxidized. …The m …357Cite 

A method to determine RNA and DNA oxidation simultaneously by HPLC-ECD: greater RNA than DNA oxidation in rat liver after doxorubicin administration.

Hofer T, Seo AY, Prudencio M, Leeuwenburgh C.Biol Chem. 2006 Jan;387(1):103-11. doi: 10.1515/BC.2006.014.PMID: 16497170

The protein denaturing agents guanidine thiocyanate and phenol/chloroform at neutral pH were found to be very efficient for the isolation of RNA and DNA from rat brain, liver and muscle. …358Cite 

Alkylthio unit as an alpha-pyrrole protecting group for use in dipyrromethane synthesis.

Thamyongkit P, Bhise AD, Taniguchi M, Lindsey JS.J Org Chem. 2006 Feb 3;71(3):903-10. doi: 10.1021/jo051806q.PMID: 16438499

The RS group was readily introduced into the pyrrole alpha-position by the reaction of 2-thiocyanatopyrrole (prepared from pyrrole, ammonium thiocyanate, and iodine) and the corresponding Grignard reagent RMgBr. Each 2-alkylthio group activated the pyrrole ring toward deut …359Cite 

Myeloperoxidase metabolizes thiocyanate in a reaction driven by nitric oxide.

Galijasevic S, Saed GM, Hazen SL, Abu-Soud HM.Biochemistry. 2006 Jan 31;45(4):1255-62. doi: 10.1021/bi051438k.PMID: 16430221

We examined the potential physiological relevance of myeloperoxidase (MPO)-nitric oxide (NO) interactions as they may relate to the cosubstrate, pseudo halide thiocyanate (SCN(-)), and substrate switching. Direct spectroscopic and rapid kinetics studies revealed that SCN(- …360Cite 

Spectrophotometric detection of iodide and chromic (III) in urine after oxidation to iodine and chromate (VI).

Paul BD, Jacobs A.J Anal Toxicol. 2005 Oct;29(7):658-63. doi: 10.1093/jat/29.7.658.PMID: 16419396

After oxidation, the samples were treated with sodium azide and ammonium thiocyanate. In presence of thiocyanate, the azide reduced iodine to iodide almost immediately, and the solutions showed negative response to ABTS. The results were compared with that of a cont …361Cite 

Interaction of hypohalous acids and heme peroxidases with unsaturated phosphatidylcholines.

Spalteholz H, Wenske K, Arnhold J.Biofactors. 2005;24(1-4):67-76. doi: 10.1002/biof.5520240108.PMID: 16403965362Cite 

Time-dependent modulation of thioredoxin reductase activity might contribute to sulforaphane-mediated inhibition of NF-kappaB binding to DNA.

Heiss E, Gerhäuser C.Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1601-11. doi: 10.1089/ars.2005.7.1601.PMID: 16356123

These findings further emphasize the importance of redox modulation or thiol reactivity for the regulation of NF-kappaB-dependent transcription by SFN. Antioxid. Redox Signal. 7, 1601-1611….363Cite 

Photochemistry of the [Fe4(mu3-S)3(NO)7]- complex in the presence of S-nucleophiles: a spectroscopic study.

Chmura A, Szaciłowski K, Waksmundzka-Góra A, Stasicka Z.Nitric Oxide. 2006 May;14(3):247-60. doi: 10.1016/j.niox.2005.10.005. Epub 2005 Dec 7.PMID: 16337819

The effect is interpreted in terms of formation of a pseudo-cubane adduct, [Fe(4)(mu(3)-S)(3)(mu(3)-SR)(NO)(7)](2-), whose existence in equilibrium with the parent complex has no detectable influence on the spectral properties, whereas shifts the redox potential and induce …364Cite 

Mechanism of nitrite oxidation by eosinophil peroxidase: implications for oxidant production and nitration by eosinophils.

van Dalen CJ, Winterbourn CC, Kettle AJ.Biochem J. 2006 Mar 15;394(Pt 3):707-13. doi: 10.1042/BJ20051470.PMID: 16336215 Free PMC article.

It uses hydrogen peroxide to oxidize thiocyanate and bromide to their respective hypohalous acids. Nitrite is also a substrate for eosinophil peroxidase. …Spectral studies showed that nitrite reduced the enzyme to its compound II form, which is a redox intermediat …365Cite 

Chemolithotrophic haloalkaliphiles from soda lakes.

Sorokin DY, Kuenen JG.FEMS Microbiol Ecol. 2005 May 1;52(3):287-95. doi: 10.1016/j.femsec.2005.02.012.PMID: 16329914 Free article. Review.

Among them, the genus Thioalkalivibrio was most metabolically diverse, including denitrifying, thiocyanate-oxidizing and facultatively alkaliphilic species. Culturable methane-oxidizing populations in the soda lakes belong to the type I methanotroph group in the Gammaprote …366Cite 

Active site structure and catalytic mechanisms of human peroxidases.

Furtmüller PG, Zederbauer M, Jantschko W, Helm J, Bogner M, Jakopitsch C, Obinger C.Arch Biochem Biophys. 2006 Jan 15;445(2):199-213. doi: 10.1016/j.abb.2005.09.017. Epub 2005 Oct 26.PMID: 16288970 Review.

Myeloperoxidase (MPO), eosinophil peroxidase, lactoperoxidase, and thyroid peroxidase are heme-containing oxidoreductases (EC 1.7.1.11), which bind ligands and/or undergo a series of redox reactions. Though sharing functional and structural homology, reflecting their phylo …367Cite 

Autocatalytic modification of the prosthetic heme of horseradish but not lactoperoxidase by thiocyanate oxidation products. A role for heme-protein covalent cross-linking.

Wojciechowski G, Huang L, Ortiz de Montellano PR.J Am Chem Soc. 2005 Nov 16;127(45):15871-9. doi: 10.1021/ja054084t.PMID: 16277530

The mammalian peroxidases eosinophil peroxidase, lactoperoxidase (LPO), and myeloperoxidase oxidize thiocyanate to the antimicrobial agents hypothiocyanous acid (HOSCN) and (SCN)2 and are part of a defense system that protects the host from infections. Horseradish peroxida …368Cite 

Kinetic determination of thiocyanate on the basis of its catalytic effect on the oxidation of methylene blue with potassium bromate.

Shishehbore MR, Nasirizadeh N, Kerdegari AA.Anal Sci. 2005 Oct;21(10):1213-6. doi: 10.2116/analsci.21.1213.PMID: 16270581 Free article.

Under the optimum experimental conditions (0.56 M of sulfuric acid, 3.9 x 10(-5) M of MB, 3.0 x 10(-3) M of bromate, 180 s, 25 degrees C), thiocyanate can be determined in the range 5.0 – 180 ng/ml. The relative standard deviations (n = 8) are 2.81 and 1.43% for 10.0 and 1 …369Cite 

Antioxidant and antiradical activities of L-carnitine.

Gülçin I.Life Sci. 2006 Jan 18;78(8):803-11. doi: 10.1016/j.lfs.2005.05.103. Epub 2005 Oct 25.PMID: 16253281

Total antioxidant activity was measured according to ferric thiocyanate method. alpha-tocopherol and trolox, a water-soluble analogue of tocopherol, were used as the reference antioxidant compounds. …370Cite 

Antioxidant activity of caffeic acid (3,4-dihydroxycinnamic acid).

Gülçin I.Toxicology. 2006 Jan 16;217(2-3):213-20. doi: 10.1016/j.tox.2005.09.011. Epub 2005 Oct 21.PMID: 16243424

In the present study, the antioxidant properties of the caffeic acid were evaluated by using different in vitro antioxidant assays such as 2-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging, 1,1-diphenyl-2-picryl-hydrazyl free radical (DPPH) scavenging, …371Cite 

Oxidation of liposomal membrane suppressed by flavonoids: quantitative structure-activity relationship.

Rackova L, Firakova S, Kostalova D, Stefek M, Sturdik E, Majekova M.Bioorg Med Chem. 2005 Dec 1;13(23):6477-84. doi: 10.1016/j.bmc.2005.07.047. Epub 2005 Sep 22.PMID: 16182538

Antioxidant activity of the set of 12 flavonoids in heterogeneous membrane system of dioleoyl phosphatidylcholine liposomes stressed by peroxidative damage induced by 2,2′-azobis-(2-amidinopropane)hydrochloride azoiniciator and evaluated by the thiocyanate method was asses …372Cite 

The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory states.

Wang JG, Mahmud SA, Thompson JA, Geng JG, Key NS, Slungaard A.Blood. 2006 Jan 15;107(2):558-65. doi: 10.1182/blood-2005-05-2152. Epub 2005 Sep 15.PMID: 16166591 Free PMC article.

In vivo, bromide (Br(-)), nitrite (NO(2)(-)), and thiocyanate (SCN(-)) compete for oxidation by eosinophil peroxidase (EPO) and H(2)O(2), yielding, respectively, HOBr, NO(2)., and HOSCN. …373Cite 

Water/silica nanoparticle interfacial kinetics of sulfate, hydrogen phosphate, and dithiocyanate radicals.

Caregnato P, Bertolotti SG, Gonzalez MC, Mártire DO.Photochem Photobiol. 2005 Nov-Dec;81(6):1526-33. doi: 10.1562/2005-07-07-RA-603.PMID: 16149862

All the results are discussed in terms of the Smoluchowski equation and redox potential of the inorganic radicals….374Cite 

Bromination and chlorination reactions of myeloperoxidase at physiological concentrations of bromide and chloride.

Senthilmohan R, Kettle AJ.Arch Biochem Biophys. 2006 Jan 15;445(2):235-44. doi: 10.1016/j.abb.2005.07.005. Epub 2005 Aug 3.PMID: 16125131

Myeloperoxidase and eosinophil peroxidase use hydrogen peroxide to oxidize halides and thiocyanate to their respective hypohalous acids. Myeloperoxidase produces mainly hypochlorous acid and hypothiocyanite. …375Cite 

Haloalkaliphilic sulfur-oxidizing bacteria in soda lakes.

Sorokin DY, Kuenen JG.FEMS Microbiol Rev. 2005 Sep;29(4):685-702. doi: 10.1016/j.femsre.2004.10.005. Epub 2004 Nov 20.PMID: 16102598 Free article. Review.

The genus Thioalkalivibrio includes mostly slowly growing species better adapted to life in hypersaline conditions and with a more versatile metabolism. It includes denitrifying, thiocyanate-utilizing and facultatively alkaliphilic species….376Cite 

Production of nitric oxide-derived reactive nitrogen species in human oral cavity and their scavenging by salivary redox components.

Takahama U, Hirota S, Oniki T.Free Radic Res. 2005 Jul;39(7):737-45. doi: 10.1080/10715760500043561.PMID: 16036353

Salivary components such as ascorbate, glutathione, uric acid and thiocyanate inhibited the transformation of DAF-2 to DAF-2T in bacterial fractions without affecting nitrite-dependent NO production. …The results obtained in this study suggest that reactive nitrogen spec …377Cite 

Effect of the lactoperoxidase system against three major causal agents of disease in mangoes.

Le Nguyen DD, Ducamp MN, Dornier M, Montet D, Loiseau G.J Food Prot. 2005 Jul;68(7):1497-500. doi: 10.4315/0362-028x-68.7.1497.PMID: 16013395 Free article.

This compound is essentially used to convert thiocyanate into hypothiocyanate during the lactoperoxidase reaction. The potential of the LPS for the postharvest treatment of the fruits for controlling microbial diseases was thus demonstrated. …378Cite 

UV-vis spectroscopic study of Co(II)/Co(III) oxidation in poly[M-protoporphyrins] films and their interaction with axial ligands.

Campo Dall’ Orto V, Carballo R, Hurst JA, Rezzano I.Spectrochim Acta A Mol Biomol Spectrosc. 2005 Jul;61(9):2089-93. doi: 10.1016/j.saa.2004.08.010.PMID: 15911396

Concentration levels of iodide of 10(-1) M showed irreversible broadening of Soret band with a maximum shift from 400 nm to 380 nm attributed to film reduction. The thiocyanate anion shows a remarkable effect on polyCo(III)PP spectra. The degree of configuration interactio …379Cite 

Role of the covalent glutamic acid 242-heme linkage in the formation and reactivity of redox intermediates of human myeloperoxidase.

Zederbauer M, Jantschko W, Neugschwandtner K, Jakopitsch C, Moguilevsky N, Obinger C, Furtmüller PG.Biochemistry. 2005 May 3;44(17):6482-91. doi: 10.1021/bi0501737.PMID: 15850382

The apparent bimolecular rate constants of compound I reduction by chloride (65 M(-)(1) s(-)(1)), bromide (5.4 x 10(4) M(-)(1) s(-)(1)), iodide (6.4 x 10(5) M(-)(1) s(-)(1)), and thiocyanate (2.2 x10(5) M(-)(1) s(-)(1)) were 500, 25, 21, and 63 times decreased compared wit …380Cite 

Standard reduction potentials of all couples of the peroxidase cycle of lactoperoxidase.

Furtmüller PG, Arnhold J, Jantschko W, Zederbauer M, Jakopitsch C, Obinger C.J Inorg Biochem. 2005 May;99(5):1220-9. doi: 10.1016/j.jinorgbio.2005.02.021.PMID: 15833345

Its predominant physiological role is to convert hydrogen peroxide and thiocyanate in hypothiocyanite. In this study, the standard reduction potentials of all redox couples involved in the halogenation and peroxidase cycle of LPO have been determined by multi-mixing …381Cite 

Short communication: hydroperoxides in circulating lipids from dairy cows: implications for bioactivity of endogenous-oxidized lipids.

Löhrke B, Viergutz T, Kanitz W, Losand B, Weiss DG, Simko M.J Dairy Sci. 2005 May;88(5):1708-10. doi: 10.3168/jds.S0022-0302(05)72843-5.PMID: 15829662 Free article.

Lipohydroperoxides (LHP) were determined in serum lipids (experiment 1) and low-density lipoprotein (experiment 2) via oxidation of ferrous to ferric ions through LHP using thiocyanate as chromogen. In experiment 1, differing milk yield and milk energy output corresponded …382Cite 

Determination of in vitro antioxidant and radical scavenging activities of propofol.

Gülçin I, Alici HA, Cesur M.Chem Pharm Bull (Tokyo). 2005 Mar;53(3):281-5. doi: 10.1248/cpb.53.281.PMID: 15744098 Free article.383Cite 

Sulforaphane, erucin, and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells.

Wang W, Wang S, Howie AF, Beckett GJ, Mithen R, Bao Y.J Agric Food Chem. 2005 Mar 9;53(5):1417-21. doi: 10.1021/jf048153j.PMID: 15740016

These results suggest that dietary ITCs are important factors in the regulation of redox status through the induction of the selenoprotein thioredoxin reductase….384Cite 

Involvement of proton transfer in the reductive repair of DNA guanyl radicals by aniline derivatives.

Ly A, Tran NQ, Sullivan K, Bandong SL, Milligan JR.Org Biomol Chem. 2005 Mar 7;3(5):917-23. doi: 10.1039/b418681h. Epub 2005 Feb 7.PMID: 15731879

By means of a radiation chemical method (gamma-irradiation of aqueous thiocyanate), we are able to produce these guanyl radicals in dilute aqueous solutions of plasmid DNA where the direct effect would otherwise be negligible. …385Cite 

Sulforaphane induces thioredoxin through the antioxidant-responsive element and attenuates retinal light damage in mice.

Tanito M, Masutani H, Kim YC, Nishikawa M, Ohira A, Yodoi J.Invest Ophthalmol Vis Sci. 2005 Mar;46(3):979-87. doi: 10.1167/iovs.04-1120.PMID: 15728556

PURPOSE: Thioredoxin (Trx) is a multifunctional endogenous redox regulator that protects cells against various types of cellular or tissue stresses. …386Cite 

Redox buffering of hypochlorous acid by thiocyanate in physiologic fluids.

Ashby MT, Carlson AC, Scott MJ.J Am Chem Soc. 2004 Dec 15;126(49):15976-7. doi: 10.1021/ja0438361.PMID: 15584727387Cite 

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.

Zhang DD, Lo SC, Cross JV, Templeton DJ, Hannink M.Mol Cell Biol. 2004 Dec;24(24):10941-53. doi: 10.1128/MCB.24.24.10941-10953.2004.PMID: 15572695 Free PMC article.

The bZIP transcription factor Nrf2 controls a genetic program that protects cells from oxidative damage and maintains cellular redox homeostasis. Keap1, a BTB-Kelch protein, is the major upstream regulator of Nrf2 and controls both the subcellular localization and steady-s …388Cite 

Catalytic oxidation of SCN- and CN- ions from aqueous solutions.

Udrea I, Avramescu S.Environ Technol. 2004 Oct;25(10):1131-41. doi: 10.1080/09593332508618379.PMID: 15551827

Oxidation of inorganic contaminants, such as thiocyanate and cyanide ions, by ozone in water has improved significantly in the presence of solid catalysts based on nickel and cobalt oxides supported on alumina. …389Cite 

Salivary thiocyanate/nitrite inhibits hydroxylation of 2-hydroxybenzoic acid induced by hydrogen peroxide/Fe(II) systems under acidic conditions: possibility of thiocyanate/nitrite-dependent scavenging of hydroxyl radical in the stomach.

Takahama U, Oniki T.Biochim Biophys Acta. 2004 Nov 18;1675(1-3):130-8. doi: 10.1016/j.bbagen.2004.09.001.PMID: 15535976

An objective of the present study is to elucidate the effects of salivary SCN- and NO2- on the hydroxylation of salicylic acid which was induced by H2O2/Fe(II) and AA/H2O2/Fe(II) systems. Thiocyanate ion inhibited the hydroxylation of salicylic acid by the above systems in …390Cite 

Mononuclear and dinuclear monoperoxovanadium(v) complexes with a hetero ligand. 1.(1) Self-decomposition reaction, detection of reactive oxygen species, and oxidizing ability.

Kanamori K, Nishida K, Miyata N, Shimoyama T, Hata K, Mihara C, Okamoto K, Abe Y, Hayakawa S, Matsugo S.Inorg Chem. 2004 Nov 1;43(22):7127-40. doi: 10.1021/ic030292f.PMID: 15500351

The induction period is reduced by the addition of acid, fluoride, thiocyanate, VO(2+), VO(2)(+), and trolox compared to the solution containing perchlorate. …391Cite 

Association/dissociation of gonadotropin subunits involves disulfide bridge disruption which is influenced by carbohydrate moiety.

Galet C, Lecompte F, Combarnous Y.Biochem Biophys Res Commun. 2004 Nov 12;324(2):868-73. doi: 10.1016/j.bbrc.2004.09.143.PMID: 15474508392Cite 

[Analytical aspects of the semiquantitative determination of urinary iodine using ferroin: value of rapid screening for iodine deficiency or excess].

Plantin-Carrenard E, Cattan F, Aurengo A, Dumérat B, Foglietti MJ, Beaudeux JL.Ann Biol Clin (Paris). 2004 Jul-Aug;62(4):456-61.PMID: 15297242 Free article. French.

In this study, we described the analytical aspects of a semiquantitative method of urinary iodine using a redox indicator, ferroin. This method allows the screening of iodine excess or deficiency in a short time (< 3 hours) with a good specificity and sensitivity. …393Cite 

Acidic aqueous decomposition of thiocyanogen.

Barnett JJ, McKee ML, Stanbury DM.Inorg Chem. 2004 Aug 9;43(16):5021-33. doi: 10.1021/ic049356s.PMID: 15285679394Cite 

Active recombinant thioredoxin h protein with antioxidant activities from sweet potato (Ipomoea batatas [L.] Lam Tainong 57) storage roots.

Huang DJ, Chen HJ, Hou WC, Lin CD, Lin YH.J Agric Food Chem. 2004 Jul 28;52(15):4720-4. doi: 10.1021/jf0498618.PMID: 15264905

Total antioxidant status, 1,1-diphenyl-2-picrylhydrazyl (DPPH) staining, reducing power method, Fe2+-chelating ability, ferric thiocyanate (FTC) method, and protection of calf thymus DNA against hydroxyl radical-induced damage were studied. …395Cite 

Anaerobic growth of the haloalkaliphilic denitrifying sulfur-oxidizing bacterium Thialkalivibrio thiocyanodenitrificans sp. nov. with thiocyanate.

Sorokin DY, Tourova TP, Antipov AN, Muyzer G, Kuenen JG.Microbiology (Reading). 2004 Jul;150(Pt 7):2435-2442. doi: 10.1099/mic.0.27015-0.PMID: 15256585 Free article.

Two strains of obligate chemolithoautotrophic sulfur-oxidizing bacteria were isolated from soda-lake sediments by enrichment culture with thiocyanate and nitrate at pH 9.9. The isolates were capable of growth with thiocyanate or thiosulfate as electron donor, either …396Cite 

Repair of oxidative guanine damage in plasmid DNA by indoles involves proton transfer between complementary bases.

Ly A, Tran NQ, Ward JF, Milligan JR.Biochemistry. 2004 Jul 20;43(28):9098-104. doi: 10.1021/bi0494830.PMID: 15248767

We have used the single electron oxidizing agent (SCN)(2)(*)(-) (generated by gamma-irradiation of aqueous thiocyanate) to produce guanyl radicals in plasmid DNA. The stable product(s) formed from these radicals can be detected after conversion with a base excision repair …397Cite 

Antioxidant and anticancer activities of organic extracts from Platycodon grandiflorum A. De Candolle roots.

Lee JY, Hwang WI, Lim ST.J Ethnopharmacol. 2004 Aug;93(2-3):409-15. doi: 10.1016/j.jep.2004.04.017.PMID: 15234786398Cite 

Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage.

Gao X, Talalay P.Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10446-51. doi: 10.1073/pnas.0403886101. Epub 2004 Jun 30.PMID: 15229324 Free PMC article.399Cite 

Thiocyanate catalyzes myeloperoxidase-initiated lipid oxidation in LDL.

Exner M, Hermann M, Hofbauer R, Hartmann B, Kapiotis S, Gmeiner B.Free Radic Biol Med. 2004 Jul 15;37(2):146-55. doi: 10.1016/j.freeradbiomed.2004.04.039.PMID: 15203186

Chloride is supposed to be the major substrate for MPO, generating reactive hypochlorous acid (HOCl), modifying LDL. The pseudo-halide thiocyanate (SCN-) has been shown to be a suitable substrate for MPO, forming reactive HOSCN/SCN*. …400Cite 

Role of thiocyanate, bromide and hypobromous acid in hydrogen peroxide-induced apoptosis.

Wagner BA, Reszka KJ, McCormick ML, Britigan BE, Evig CB, Burns CP.Free Radic Res. 2004 Feb;38(2):167-75. doi: 10.1080/10715760310001643302.PMID: 15104210

We now report that when chloride is replaced by the pseudohalide thiocyanate, there is little or no H2O2-induced apoptosis. Furthermore, thiocyanate inhibits H2O2-induced apoptosis when chloride is present at physiological concentrations, and this occurs at thioc …

401Cite 

The inhibitory effects of 12 medicinal plants and their component compounds on lipid peroxidation.

Cho EJ, Yokozawa T, Rhyu DY, Kim HY, Shibahara N, Park JC.Am J Chin Med. 2003;31(6):907-17. doi: 10.1142/S0192415X03001648.PMID: 14992543

The antioxidative activities of 12 medicinal plants and the compounds isolated from them were investigated using the thiocyanate method to evaluate inhibitory effects on lipid peroxidation in the linoleic acid system. …402Cite 

Enhanced protein glutathiolation and oxidative stress in cigarette smokers.

Muscat JE, Kleinman W, Colosimo S, Muir A, Lazarus P, Park J, Richie JP Jr.Free Radic Biol Med. 2004 Feb 15;36(4):464-70. doi: 10.1016/j.freeradbiomed.2003.11.018.PMID: 14975449

The glutathiolation of proteins at key Cys residues is considered an important redox-sensitive, posttranslational signaling mechanism in the regulation of critical cellular functions. …The relationship was dose-dependent, with blood GSSP levels significantly correlated w …403Cite 

Antioxidative activity and protective effect against ethanol-induced gastric mucosal damage of a potato protein hydrolysate.

Kudoh K, Matsumoto M, Onodera S, Takeda Y, Ando K, Shiomi N.J Nutr Sci Vitaminol (Tokyo). 2003 Dec;49(6):451-5. doi: 10.3177/jnsv.49.451.PMID: 14974739

The Po-P obtained by proteolysis with Amano P and pancreatin inhibited linoleic acid oxidation either by 83%, at its coexistent 0.005% in a ferric thiocyanate assay system or by 32% at its coexistent 0.0002% in a beta-carotene decolorization assay system. …404Cite 

Voltammetric studies of the catalytic mechanism of the respiratory nitrate reductase from Escherichia coli: how nitrate reduction and inhibition depend on the oxidation state of the active site.

Elliott SJ, Hoke KR, Heffron K, Palak M, Rothery RA, Weiner JH, Armstrong FA.Biochemistry. 2004 Jan 27;43(3):799-807. doi: 10.1021/bi035869j.PMID: 14730985

However, an alternative interpretation, that nitrate binding is affected by a change in the redox state of the pterin, cannot be ruled out. This proposal, implicating a specific redox transition at the active site, is supported by experiments carried out using the i …405Cite 

Repair of oxidative DNA damage by amino acids.

Milligan JR, Aguilera JA, Ly A, Tran NQ, Hoang O, Ward JF.Nucleic Acids Res. 2003 Nov 1;31(21):6258-63. doi: 10.1093/nar/gkg816.PMID: 14576314 Free PMC article.

We have produced guanyl radicals in DNA by using the single electron oxidizing agent (SCN)2-, itself derived from the indirect effect of ionizing radiation via thiocyanate scavenging of OH. We have examined the reactivity of guanyl radicals in plasmid DNA with the six most …406Cite 

Structural stability of human alpha-thrombin studied by disulfide reduction and scrambling.

Rajesh Singh R, Chang JY.Biochim Biophys Acta. 2003 Sep 23;1651(1-2):85-92. doi: 10.1016/s1570-9639(03)00238-3.PMID: 14499592

Conformational stability of alpha-thrombin was investigated by the technique of disulfide scrambling. alpha-Thrombin denatures by scrambling its native disulfide bonds in the presence of denaturant [urea, guanidine hydrochloride (GdmCl) or guanidine thiocyanate (GdmSCN)] a …407Cite 

Nitrite-catalase interaction as an important element of nitrite toxicity.

Titov VY, Petrenko YM.Biochemistry (Mosc). 2003 Jun;68(6):627-33. doi: 10.1023/a:1024609624652.PMID: 12943506

It was established that nitrite in the presence of chloride, bromide, and thiocyanate decreases the rate of hydrogen peroxide decomposition by catalase. The decrease was recorded by the permanganatometric method and by a method of dynamic calorimetry. …However, in the ab …408Cite 

Oxygen uptake during the mixing of saliva with ascorbic acid under acidic conditions: possibility of its occurrence in the stomach.

Takahama U, Hirota S, Yamamoto A, Oniki T.FEBS Lett. 2003 Aug 28;550(1-3):64-8. doi: 10.1016/s0014-5793(03)00820-2.PMID: 12935887 Free article.409Cite 

Antioxidant properties of extracts from Alchornea laxiflora (Benth) Pax and Hoffman.

Farombi EO, Ogundipe OO, Samuel Uhunwangho E, Adeyanju MA, Olarenwaju Moody J.Phytother Res. 2003 Aug;17(7):713-6. doi: 10.1002/ptr.1050.PMID: 12916064

The antioxidant activities of the leaf and root extracts of Alchornea laxiflora, a plant used locally for the preservation of food items in Nigeria, were evaluated using the ferric thiocyanate method, horseradish peroxidase catalysed oxidation of 2,2 azinobis-(3-ethylbenzo …410Cite 

A unique autocatalytic process and evidence for a concerted-stepwise mechanism transition in the dissociative electron-transfer reduction of aryl thiocyanates.

Houmam A, Hamed EM, Still IW.J Am Chem Soc. 2003 Jun 18;125(24):7258-65. doi: 10.1021/ja028542z.PMID: 12797799

Electrochemical reduction of p-methyl-, p-methoxy-, and 3,5-dinitrophenyl thiocyanates as well as p-methyl- and p-methoxyphenyl disulfides was investigated in acetonitrile at an inert electrode. This series of compounds reveals a striking change in the reductive cleavage m …411Cite 

Evaluation of the anti-oxidative effect (in vitro) of tea polyphenols.

Hashimoto F, Ono M, Masuoka C, Ito Y, Sakata Y, Shimizu K, Nonaka G, Nishioka I, Nohara T.Biosci Biotechnol Biochem. 2003 Feb;67(2):396-401. doi: 10.1271/bbb.67.396.PMID: 12729007 Free article.

Forty-three polyphenols from tea leaves were evaluated for their anti-oxidative effect against lipid peroxidation by the ferric thiocyanate method in vitro. Among these, 1,4,6-tri-O-galloyl-beta-D-glucose (hydrolyzable tannin) showed the highest anti-oxidative activity aga …412Cite 

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression.

McMahon M, Itoh K, Yamamoto M, Hayes JD.J Biol Chem. 2003 Jun 13;278(24):21592-600. doi: 10.1074/jbc.M300931200. Epub 2003 Apr 7.PMID: 12682069 Free article.

By heterologously expressing in COS1 cells epitope-tagged Nrf2 and an Nrf2DeltaETGE mutant lacking the Keap1-binding site, in both the presence and absence of Keap1 we demonstrate that Nrf2 is subject to ubiquitination and proteasomal degradation independently of both Keap1 and t …413Cite 

Valorization of cauliflower (Brassica oleracea L. var. botrytis) by-products as a source of antioxidant phenolics.

Llorach R, Espín JC, Tomás-Barberán FA, Ferreres F.J Agric Food Chem. 2003 Apr 9;51(8):2181-7. doi: 10.1021/jf021056a.PMID: 12670153

Cauliflower byproduct extracts showed significant free radical scavenging activity (vs both DPPH(*) and ABTS(*)(+) radicals), ferric reducing ability (FRAP assay), and capacity to inhibit lipid peroxidation (ferric thiocyanate assay). In addition, the antioxidant activity …414Cite 

Taming of a poison: biosynthesis of the NiFe-hydrogenase cyanide ligands.

Reissmann S, Hochleitner E, Wang H, Paschos A, Lottspeich F, Glass RS, Böck A.Science. 2003 Feb 14;299(5609):1067-70. doi: 10.1126/science.1080972.PMID: 12586941

HypE dehydrates the S-carbamoyl moiety in an adenosine triphosphate-dependent process to yield the enzyme thiocyanate. Chemical model reactions corroborate the feasibility of this unprecedented biosynthetic route and show that thiocyanates can donate CN to iron. …415Cite 

Inhibition of oral peroxidase activity by cigarette smoke: in vivo and in vitro studies.

Reznick AZ, Klein I, Eiserich JP, Cross CE, Nagler RM.Free Radic Biol Med. 2003 Feb 1;34(3):377-84. doi: 10.1016/s0891-5849(02)01297-2.PMID: 12543253

Accordingly, most of the time the oral epithelium of heavy smokers is essentially unprotected by OPO against the deleterious effects of thiocyanate ions and hydroxyl radicals produced by unremoved hydrogen peroxide in the presence of the salivary redox-active metal …416Cite 

Cellular background level of 8-oxo-7,8-dihydro-2′-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up.

Ravanat JL, Douki T, Duez P, Gremaud E, Herbert K, Hofer T, Lasserre L, Saint-Pierre C, Favier A, Cadet J.Carcinogenesis. 2002 Nov;23(11):1911-8. doi: 10.1093/carcin/23.11.1911.PMID: 12419840

The comparison of different DNA extraction protocols led to the conclusion that artefactual DNA oxidation during the extraction step could be minimized if: (i) nuclei are isolated after cell lysis; (ii) desferrioxamine, a transition metal chelator is added to the different extrac …417Cite 

3-Mercaptopyruvate sulfurtransferase of Leishmania contains an unusual C-terminal extension and is involved in thioredoxin and antioxidant metabolism.

Williams RA, Kelly SM, Mottram JC, Coombs GH.J Biol Chem. 2003 Jan 17;278(3):1480-6. doi: 10.1074/jbc.M209395200. Epub 2002 Nov 4.PMID: 12419809 Free article.

The leishmanial recombinant enzymes exhibited high activity toward 3-mercaptopyruvate and catalyzed the transfer of sulfane sulfur to cyanide to form thiocyanate. They also used thiosulfate as a substrate and reduced thioredoxin as the accepting nucleophile, the latter bei …418Cite 

Antioxidant property of an ethanol extract of the stem of Opuntia ficus-indica var. saboten.

Lee JC, Kim HR, Kim J, Jang YS.J Agric Food Chem. 2002 Oct 23;50(22):6490-6. doi: 10.1021/jf020388c.PMID: 12381138

The ethanol extract exhibited a concentration-dependent inhibition of linoleic acid oxidation in a thiocyanate assay system. In addition, the OFS extract showed dose-dependent free-radical scavenging activity, including DPPH radicals, superoxide anions (O(2)(*-)), and hydr …419Cite 

Iron(VI) and iron(V) oxidation of thiocyanate.

Sharma VK, Burnett CR, O’Connor DB, Cabelli D.Environ Sci Technol. 2002 Oct 1;36(19):4182-6. doi: 10.1021/es020570u.PMID: 12380093

Thiocyanate (SCN-) is used in many industrial processes and is commonly found in industrial and mining waste-waters. The removal of SCN- is required because of its toxic effects. The oxidation of thiocyanate (SCN-) by environmentally friendly oxidants, Fe(VI) and Fe …420Cite 

Kinetics and mechanism of the formation of nitroprusside from aquapentacyanoferrate(III) and NO: complex formation controlled by outer-sphere electron transfer.

Roncaroli F, Olabe JA, van Eldik R.Inorg Chem. 2002 Oct 21;41(21):5417-25. doi: 10.1021/ic020288o.PMID: 12377036

The aquapentacyanoferrate(II) ion was detected as a reactive intermediate in the reaction of aquapentacyanoferrate(III) with NO, by using pyrazine and thiocyanate as scavengers for this intermediate. In addition, the reactions of other [Fe(III)(CN)(5)L](n-) complexes (L = …421Cite 

Reaction of lactoperoxidase compound I with halides and thiocyanate.

Furtmüller PG, Jantschko W, Regelsberger G, Jakopitsch C, Arnhold J, Obinger C.Biochemistry. 2002 Oct 1;41(39):11895-900. doi: 10.1021/bi026326x.PMID: 12269834

This study for the first time presents transient kinetic measurements of the reactivity of its competent redox intermediate compound I with halides and thiocyanate, using the sequential stopped-flow technique. …At pH 7 and 15 degrees C, the two-electron reduction …422Cite 

On the in vitro antioxidative properties of melatonin.

Gulcin I, Buyukokuroglu ME, Oktay M, Kufrevioglu OI.J Pineal Res. 2002 Oct;33(3):167-71. doi: 10.1034/j.1600-079x.2002.20920.x.PMID: 12220332

Thus, the total in vitro antioxidant activity of melatonin was studied using a thiocyanate method. Additionally, the reducing power, the superoxide anion scavenging activity and free radical scavenging activity of melatonin were determined. …423Cite 

Artichoke (Cynara scolymus L.) byproducts as a potential source of health-promoting antioxidant phenolics.

Llorach R, Espín JC, Tomás-Barberán FA, Ferreres F.J Agric Food Chem. 2002 Jun 5;50(12):3458-64. doi: 10.1021/jf0200570.PMID: 12033811

Artichoke extracts from industrial byproducts showed a high free radical scavenging activity (versus both DPPH* and ABTS*+ radicals) as well as capacity to inhibit lipid peroxidation (ferric thiocyanate method). According to these results, the use of artichoke extracts fro …424Cite 

Photochemical electron transfer reactions of tirapazamine.

Poole JS, Hadad CM, Platz MS, Fredin ZP, Pickard L, Guerrero EL, Kessler M, Chowdhury G, Kotandeniya D, Gates KS.Photochem Photobiol. 2002 Apr;75(4):339-45. doi: 10.1562/0031-8655(2002)075<0339:petrot>2.0.co;2.PMID: 12003122

Linear Stern-Volmer fluorescence quenching plots are observed with sodium azide, potassium thiocyanate, guanosine monophosphate and tryptophan (Trp) methyl ester hydrochloride. Guanosine monophosphate, tyrosine (Tyr) methyl ester hydrochloride and Trp methyl ester hydrochl …425Cite 

Kinetic spectrophotometric determination of thiocyanate based on its inhibitory effect on the oxidation of methyl red by bromate.

Ghasemi J, Amini R, Afkhami A.Anal Sci. 2001 Mar;17(3):435-7. doi: 10.2116/analsci.17.435.PMID: 11990623 Free article.

A kinetic spectrophotometric method for measuring thiocyanate is described. The proposed method is based on the inhibitory effect of thiocyanate on the oxidation of Methyl Red by bromate in the presence of nitrite, which was monitored at 520 nm. …This method has b …426Cite 

Antioxidant activity of phenolic compounds isolated from Mesona procumbens Hemsl.

Hung CY, Yen GC.J Agric Food Chem. 2002 May 8;50(10):2993-7. doi: 10.1021/jf011454y.PMID: 11982431

The antioxidant capability of isolated compounds was also determined using the thiocyanate system and the erythrocyte ghost system. The results indicate that the phenolic acids could be important antioxidant components in Hsian-tsao, among which caffeic acid with the highe …427Cite 

Thioalkalivibrio thiocyanoxidans sp. nov. and Thioalkalivibrio paradoxus sp. nov., novel alkaliphilic, obligately autotrophic, sulfur-oxidizing bacteria capable of growth on thiocyanate, from soda lakes.

Sorokin DY, Tourova TP, Lysenko AM, Mityushina LL, Kuenen JG.Int J Syst Evol Microbiol. 2002 Mar;52(Pt 2):657-664. doi: 10.1099/00207713-52-2-657.PMID: 11931180

Nine strains of haloalkaliphilic, obligately autotrophic, sulfur-oxidizing bacteria able to grow with thiocyanate (SCN-) as the sole energy and nitrogen source were isolated from soda lakes in South-East Siberia, Kenya and Egypt after enrichment on sodium carbonate mineral …428Cite 

Defects in leukocyte-mediated initiation of lipid peroxidation in plasma as studied in myeloperoxidase-deficient subjects: systematic identification of multiple endogenous diffusible substrates for myeloperoxidase in plasma.

Zhang R, Shen Z, Nauseef WM, Hazen SL.Blood. 2002 Mar 1;99(5):1802-10.PMID: 11861298 Free article.

Subsequent HPLC fractionation of plasma filtrate (10-kd MWt cutoff) by sequential column chromatography identified nitrite, tyrosine, and thiocyanate as major endogenous substrates and 17 beta-estradiol as a novel minor endogenous substrate in plasma for MPO in promoting p …429Cite 

Formation of trithiocyanate in the oxidation of aqueous thiocyanate.

Barnett JJ, Stanbury DM.Inorg Chem. 2002 Jan 28;41(2):164-6. doi: 10.1021/ic015597d.PMID: 11800603430Cite 

Redox equilibrium between guanyl radicals and thiocyanate influences base damage yields in gamma irradiated plasmid DNA. Estimation of the reduction potential of guanyl radicals in plasmid DNA in aqueous solution at physiological ionic strength.

Milligan JR, Aguilera JA, Ward JF.Int J Radiat Biol. 2001 Dec;77(12):1195-205. doi: 10.1080/09553000110083988.PMID: 11747544

MATERIALS AND METHODS: Aqueous solutions of plasmid DNA and thiocyanate ions were subjected to 137Cs gamma-irradiation. After irradiation, the plasmid was incubated with the E. coli base excision repair endonuclease formamidopyrimidine-DNA N-glycosylase (FPG). …A good ag …431Cite 

In vitro antioxidant properties of dantrolene sodium.

Büyükokuroğlu ME, GülçIn I, Oktay M, Küfrevioğlu OI.Pharmacol Res. 2001 Dec;44(6):491-4. doi: 10.1006/phrs.2001.0890.PMID: 11735355

For this reason, the in vitro antioxidant effects of dantrolene sodium were studied using thiocyanate methods. Additionally, the reducing power and free radical scavenging activity were determined. …432Cite 

C-H activation with elemental sulfur: synthesis of cyclic thioureas from formaldehyde aminals and S8.

Denk MK, Gupta S, Brownie J, Tajammul S, Lough AJ.Chemistry. 2001 Oct 15;7(20):4477-86. doi: 10.1002/1521-3765(20011015)7:20<4477::aid-chem4477>3.0.co;2-i.PMID: 11695682

The reaction constitutes a new, solvent-free method for the synthesis of thioureas that eliminates the toxic and highly flammable CS2. For R = tBu, the ionic carbenium thiocyanates [LCH]+ SCN- dominate the product spectrum and the respective thioureas are obtained in low y …433Cite 

Reaction of guanyl radicals in plasmid DNA with biological reductants: chemical repair of DNA damage produced by the direct effect of ionizing radiation.

Milligan JR, Aguilera JA, Mares EJ, Paglinawan RA, Ward JF.Int J Radiat Biol. 2001 Nov;77(11):1095-108. doi: 10.1080/09553000110069119.PMID: 11683980

MATERIALS AND METHODS: Aqueous solutions of plasmid DNA containing 10(-3) mol dm(-3) thiocyanate or thallous ions and a reducing agent (azide, nitrite, ferrocyanide, hexachloroiridate(III), iodide, ascorbate, glutathione, glutathione disulphide, methionine, tyrosine, 5-hyd …434Cite 

Copper(II) Complexes with Unusual Axial Phenolate Coordination as Structural Models for the Active Site in Galactose Oxidase: X-ray Crystal Structures and Spectral and Redox Properties of [Cu(bpnp)X] Complexes.

Vaidyanathan M, Viswanathan R, Palaniandavar M, Balasubramanian T, Prabhaharan P, Muthiah TP.Inorg Chem. 1998 Dec 14;37(25):6418-6427. doi: 10.1021/ic971567s.PMID: 11670761

The unusual occupation of phenolate ion in the axial site is possibly due to the steric constraint at copper imposed by the 5,5,6-chelate ring sequence. The thiocyanate/acetate coordination geometry is reminiscent of the active site of the radical copper enzyme galactose o …435Cite 

A transient kinetic study on the reactivity of recombinant unprocessed monomeric myeloperoxidase.

Furtmüller PG, Jantschko W, Regelsberger G, Jakopitsch C, Moguilevsky N, Obinger C.FEBS Lett. 2001 Aug 17;503(2-3):147-50. doi: 10.1016/s0014-5793(01)02725-9.PMID: 11513872 Free article.

Spectral and kinetic features of the redox intermediates of human recombinant unprocessed monomeric myeloperoxidase (recMPO), purified from an engineered Chinese hamster ovary cell line, were studied by the multi-mixing stopped-flow technique. …Firstly, hydrogen peroxide …436Cite 

New inhibitors of iron-containing nitrile hydratases.

Bonnet D, Stevens JM, de Sousa RA, Sari MA, Mansuy D, Artaud I.J Biochem. 2001 Aug;130(2):227-33. doi: 10.1093/oxfordjournals.jbchem.a002976.PMID: 11481039 Free article.

Following this approach we report three novel inhibitors of NHases. In addition, we report thiocyanate reagents that can be used to monitor NHase activity spectroscopically….437Cite 

Comparison of low-density lipoprotein modification by myeloperoxidase-derived hypochlorous and hypobromous acids.

Carr AC, Decker EA, Park Y, Frei B.Free Radic Biol Med. 2001 Jul 1;31(1):62-72. doi: 10.1016/s0891-5849(01)00552-4.PMID: 11425491

Interestingly, even at physiological concentrations of the two halides (100 mM Cl(-), 100 microM Br(-)), MPO utilized a portion of the Br(-) to oxidize apoB cysteine residues. MPO also utilized the pseudohalide thiocyanate to oxidize apoB cysteine residues. Our data show t …438Cite 

Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms.

Heiss E, Herhaus C, Klimo K, Bartsch H, Gerhäuser C.J Biol Chem. 2001 Aug 24;276(34):32008-15. doi: 10.1074/jbc.M104794200. Epub 2001 Jun 15.PMID: 11410599 Free article.

Because SFN can interact with thiol groups by dithiocarbamate formation, it may impair the redox-sensitive DNA binding and transactivation of NF-kappa B. Sulforaphane could either directly inactivate NF-kappa B subunits by binding to essential Cys residues or interact with …439Cite 

Biological activity of complexes derived from pyridine-2-carbaldehyde thiosemicarbazone. Structure of.

García-Tojal J, García-Orad A, Díaz AA, Serra JL, Urtiaga MK, Arriortua MI, Rojo T.J Inorg Biochem. 2001 Apr;84(3-4):271-8. doi: 10.1016/s0162-0134(01)00184-2.PMID: 11374590

The metal ion is bonded to one sulfur and two nitrogen atoms of each thiosemicarbazone molecule. The thiocyanate molecules act as counterions. The copper(II) and iron(III) complexes react with reduced glutathione and 2-mercaptoethanol. The reaction of compound 1 with the a …440Cite 

Diverse heteroleptic ytterbium(III) thiocyanate complexes by oxidation from bis(thiocyanato)ytterbium(II).

Deacon GB, Forsyth CM, Wilkinson DL.Chemistry. 2001 Apr 17;7(8):1784-95. doi: 10.1002/1521-3765(20010417)7:8<1784::aid-chem17840>3.0.co;2-7.PMID: 11349921

The new ytterbium(II) thiocyanate complex [Yb(NCS)2(thf)2] (1), synthesised by redox transmetallation between [Hg(SCN)2] and ytterbium metal in THF at room temperature, gave monomeric, eight coordinate [Yb-(NCS)2(dme)3] (2, dme = 1,2-dimethoxyethane) on crystallisat …441Cite 

Iron chelation and related properties of Podophyllum hexandrum, a possible role in radioprotection.

Kumar IP, Goel HC.Indian J Exp Biol. 2000 Oct;38(10):1003-6.PMID: 11324151

Chelation, oxidation and reduction of Fe2+ and Fe3+ were measured using chelating agents 2-2′ bipiridyl and potassium thiocyanate respectively. Podophyllum extract, in a dose dependent manner, chelated Fe2+ more efficiently than Fe3+ and also modulated Fe2+/Fe3+ ratio. … …442Cite 

Comparative evaluation of antioxidant potential of alaternin (2-hydroxyemodin) and emodin.

Choi JS, Chung HY, Jung HA, Park HJ, Yokozawa T.J Agric Food Chem. 2000 Dec;48(12):6347-51. doi: 10.1021/jf000936r.PMID: 11312806

The antioxidant activities of alaternin (2-hydroxyemodin) and emodin were compared for their respective potentials to inhibit lipid peroxidation in the linoleic acid system by the thiocyanate method, to inhibit total reactive oxygen species generation in kidney homogenates …443Cite 

Redox reactivity of guanyl radicals in plasmid DNA.

Milligan JR, Aguilera JA, Nguyen JV, Ward JF.Int J Radiat Biol. 2001 Mar;77(3):281-93. doi: 10.1080/09553000010013436.PMID: 11258842

PURPOSE: It has been previously argued that gamma-irradiation of plasmid DNA in the presence of thiocyanate ions produces products recognized by the E. coli base excision-repair endonuclease formamidopyrimidine-DNA N-glycosylase (FPG), and there that derive from an interme …444Cite 

Microbial thiocyanate utilization under highly alkaline conditions.

Sorokin DY, Tourova TP, Lysenko AM, Kuenen JG.Appl Environ Microbiol. 2001 Feb;67(2):528-38. doi: 10.1128/AEM.67.2.528-538.2001.PMID: 11157213 Free PMC article.

The third group included obligately autotrophic sulfur-oxidizing alkaliphilic bacteria able to utilize thiocyanate as a sole source of energy. These bacteria could be enriched on mineral medium with thiocyanate at pH 10. Growth with thiocyanate was usually mu …445Cite 

Spectral and kinetic studies on the formation of eosinophil peroxidase compound I and its reaction with halides and thiocyanate.

Furtmüller PG, Burner U, Regelsberger G, Obinger C.Biochemistry. 2000 Dec 19;39(50):15578-84. doi: 10.1021/bi0020271.PMID: 11112545

This study for the first time presents transient kinetic measurements of the formation of compound I of human eosinophil peroxidase (EPO) and its reaction with halides and thiocyanate, using the sequential-mixing stopped-flow technique. Addition of 1 equiv of hydrogen pero …446Cite 

Thiocyanate binding to the molybdenum centre of the periplasmic nitrate reductase from Paracoccus pantotrophus.

Butler CS, Charnock JM, Garner CD, Thomson AJ, Ferguson SJ, Berks BC, Richardson DJ.Biochem J. 2000 Dec 15;352 Pt 3(Pt 3):859-64.PMID: 11104696 Free PMC article.

In the present study the effect of KSCN (potassium thiocyanate) as an inhibitor and Mo ligand has been investigated. Results are presented that show NAP is sensitive to SCN(-) (thiocyanate) inhibition, with SCN(-) acting as a competitive inhibitor of nitrate (K(i) a …447Cite 

Persuasive evidence that quinone reductase type 1 (DT diaphorase) protects cells against the toxicity of electrophiles and reactive forms of oxygen.

Dinkova-Kostova AT, Talalay P.Free Radic Biol Med. 2000 Aug;29(3-4):231-40. doi: 10.1016/s0891-5849(00)00300-2.PMID: 11035251 Free article. Review.

An extensive body of evidence supports the conclusion that by catalyzing obligatory two-electron reductions of quinones to hydroquinones, NAD(P)H:quinone reductase (QR1) protects cells against the deleterious effects of redox cycling of quinones, their ability to deplete g …448Cite 

Role of eosinophil peroxidase in the origins of protein oxidation in asthma.

Mitra SN, Slungaard A, Hazen SL.Redox Rep. 2000;5(4):215-24. doi: 10.1179/135100000101535771.PMID: 10994876 Free article. Review.449Cite 

The reactivity of myeloperoxidase compound I formed with hypochlorous acid.

Furtmüller PG, Burner U, Jantschko W, Regelsberger G, Obinger C.Redox Rep. 2000;5(4):173-8. doi: 10.1179/135100000101535717.PMID: 10994870 Free article.

Furthermore, the kinetics and spectra of the reactions of halides and thiocyanate and of physiologically relevant one-electron donors (ascorbate, nitrite, tyrosine and hydrogen peroxide) with this compound I were investigated using the sequential-mixing technique. The resu …450Cite 

Production of rhodanese by bacteria present in bio-oxidation plants used to recover gold from arsenopyrite concentrates.

Gardner MN, Rawlings DE.J Appl Microbiol. 2000 Jul;89(1):185-90. doi: 10.1046/j.1365-2672.2000.01117.x.PMID: 10945796

Although the sulphur-oxidizing bacteria were clearly able to convert cyanide to thiocyanate, it is unlikely that this rhodanese activity is responsible for the excessive cyanide wastage at the high pH values associated with the gold solubilization process….451Cite 

Kinetic studies on the oxidation of nitrite by horseradish peroxidase and lactoperoxidase.

Gebicka L.Acta Biochim Pol. 1999;46(4):919-27.PMID: 10824860

Nitrite, at neutral pH, influenced measurements of activity of lactoperoxidase with typical substrates like 2,2′-azino-bis[ethyl-benzothiazoline-(6)-sulphonic acid] (ABTS), guaiacol or thiocyanate (SCN-). The rate of ABTS and guaiacol oxidation increased linearly with nitr …452Cite 

Antioxidant properties of a North American ginseng extract.

Kitts DD, Wijewickreme AN, Hu C.Mol Cell Biochem. 2000 Jan;203(1-2):1-10. doi: 10.1023/a:1007078414639.PMID: 10724326

In a metal-free linoleic acid emulsion, NAGE exhibited a significant (p < or = 0.05) concentration (0.01-10 mg/mL) dependent mitigation of lipid oxidation as assessed by the ammonium thiocyanate method. Similar results were obtained when NAGE was incubated in a methyl l…453Cite 

EPR investigation of Cu2+-substituted photosynthetic bacterial reaction centers: evidence for histidine ligation at the surface metal site.

Utschig LM, Poluektov O, Tiede DM, Thurnauer MC.Biochemistry. 2000 Mar 21;39(11):2961-9. doi: 10.1021/bi991800t.PMID: 10715116454Cite 

Simple method for determination of thiocyanate in urine.

Haque MR, Bradbury JH.Clin Chem. 1999 Sep;45(9):1459-64.PMID: 10471648

Over the range 0-100 mg/L, there was a linear relationship given by the equation: thiocyanate content (mg/L) = 78 x absorbance. RESULTS: The picrate thiocyanate method gave no interference with urine samples containing protein at less than 7 g/L, 21 amino acids, his …455Cite 

The single cysteine residue of the Sud protein is required for its function as a polysulfide-sulfur transferase in Wolinella succinogenes.

Klimmek O, Stein T, Pisa R, Simon J, Kröger A.Eur J Biochem. 1999 Jul;263(1):79-84. doi: 10.1046/j.1432-1327.1999.00461.x.PMID: 10429190 Free article.

After this treatment, Sud-His6 retained one sulfur atom per monomer; thiocyanate was formed upon addition of cyanide to the preparation. After incubation of Sud-His6 with polysulfide, a proportion of the Sud-His6 monomers carried one or two sulfur atoms, as shown by matrix …456Cite 

Antioxidant effects of dopamine and related compounds.

Yen GC, Hsieh CL.Biosci Biotechnol Biochem. 1997 Oct;61(10):1646-9. doi: 10.1271/bbb.61.1646.PMID: 10336274 Free article.

The antioxidant effect of dopamine and its related compounds on peroxidation of linoleic acid were in the order of dopamine > alpha-tocopherol = tyramine > tyrosine > noradrenaline as measured by the thiocyanate method. These amine compounds had reducing power, an …457Cite 

Formation of glucoraphanin by chemoselective oxidation of natural glucoerucin: a chemoenzymatic route to sulforaphane.

Iori R, Bernardi R, Gueyrard D, Rollin P, Palmieri S.Bioorg Med Chem Lett. 1999 Apr 5;9(7):1047-8. doi: 10.1016/s0960-894x(99)00136-5.PMID: 10230637458Cite 

Yield of DNA strand breaks after base oxidation of plasmid DNA.

Milligan JR, Aguilera JA, Nguyen TT, Ward JF, Kow YW, He B, Cunningham RP.Radiat Res. 1999 Mar;151(3):334-42.PMID: 10073672

We have irradiated aerobic aqueous solutions of plasmid DNA with 137Cs gamma rays in the presence of inorganic radical scavengers including nitrite, iodide, azide, thiocyanate and bromide. These scavengers react with the strongly oxidizing hydroxyl radical (*OH) to produce …459Cite 

Reaction of myeloperoxidase compound I with chloride, bromide, iodide, and thiocyanate.

Furtmüller PG, Burner U, Obinger C.Biochemistry. 1998 Dec 22;37(51):17923-30. doi: 10.1021/bi9818772.PMID: 9922160

The enzyme uses hydrogen peroxide to oxidize chloride (Cl-), bromide (Br-), iodide (I-), and the pseudohalide thiocyanate (SCN-) to their respective hypohalous acids. This study for the first time presents transient kinetic measurements of the oxidation of these halides an …460Cite 

Mechanism of horseradish peroxidase catalyzed epinephrine oxidation: obligatory role of endogenous O2- and H2O2.

Adak S, Bandyopadhyay U, Bandyopadhyay D, Banerjee RK.Biochemistry. 1998 Dec 1;37(48):16922-33. doi: 10.1021/bi980899l.PMID: 9836585461Cite 

Subunit-specific interactions of cyanide with the N-methyl-D-aspartate receptor.

Arden SR, Sinor JD, Potthoff WK, Aizenman E.J Biol Chem. 1998 Aug 21;273(34):21505-11. doi: 10.1074/jbc.273.34.21505.PMID: 9705279 Free article.

Some of the effects of cyanide on NR1/NR2B receptors may be mediated by the formation of a thiocyanate adduct with a cysteine residue located in NR1. Cyanide thus is able to distinguish chemically between two different N-methyl-D-aspartate receptor subtypes and produce dia …462Cite 

Haem propionates control oxidative and reductive activities of horseradish peroxidase by maintaining the correct orientation of the haem.

Adak S, Banerjee RK.Biochem J. 1998 Aug 15;334 ( Pt 1)(Pt 1):51-6. doi: 10.1042/bj3340051.PMID: 9693101 Free PMC article.

The reconstituted enzyme oxidizes neither guaiacol (aromatic electron donor) nor iodide or thiocyanate (inorganic donor). Although the reconstituted enzyme binds guaiacol with a similar Kd (13 mM) to that of the native enzyme (10 mM), the Kd for SCN- binding (5 mM) is decr …463Cite 

The function of the periplasmic Sud protein in polysulfide respiration of Wolinella succinogenes.

Klimmek O, Kreis V, Klein C, Simon J, Wittershagen A, Kröger A.Eur J Biochem. 1998 Apr 1;253(1):263-9. doi: 10.1046/j.1432-1327.1998.2530263.x.PMID: 9578485 Free article.

Sud modified by a C-terminal His-tag (Sud-His6) was produced in Escherichia coli by expression of the sud gene. Sud-His6 catalyzed thiocyanate formation from cyanide and polysulfide. The Vmax of this activity was more than one order of magnitude higher than that of sulfide …464Cite 

Biodegradation of cyanides, cyanates and thiocyanates to ammonia and carbon dioxide by immobilized cells of Pseudomonas putida.

Chapatwala KD, Babu GR, Vijaya OK, Kumar KP, Wolfram JH.J Ind Microbiol Biotechnol. 1998 Jan;20(1):28-33. doi: 10.1038/sj.jim.2900469.PMID: 9523454

Immobilized cells of P. putida degraded cyanides, cyanates and thiocyanates to NH3 and CO2. Use of Na[14C]-CN showed that 70% of carbon of Na[14C]-CN was converted into 14CO2 and only 10% was associated with the cell biomass. …465Cite 

Cyanate-mediated inhibition of neutrophil myeloperoxidase activity.

Qian M, Eaton JW, Wolff SP.Biochem J. 1997 Aug 15;326 ( Pt 1)(Pt 1):159-66. doi: 10.1042/bj3260159.PMID: 9337863 Free PMC article.

We hypothesized that CNO- (which resembles the ‘pseudohalide’ thiocyanate, an alternative substrate for MPO) might somehow interfere with the activity of MPO. …466Cite 

Reduction of thiocyanate, cyanate, and carbon disulfide by nitrogenase: kinetic characterization and EPR spectroscopic analysis.

Rasche ME, Seefeldt LC.Biochemistry. 1997 Jul 15;36(28):8574-85. doi: 10.1021/bi970217e.PMID: 9214303467Cite 

Validation of a simple, manual urinary iodine method for estimating the prevalence of iodine-deficiency disorders, and interlaboratory comparison with other methods.

May SL, May WA, Bourdoux PP, Pino S, Sullivan KM, Maberly GF.Am J Clin Nutr. 1997 May;65(5):1441-5. doi: 10.1093/ajcn/65.5.1441.PMID: 9129474

There were no apparent effects on the method by thiocyanate, a known interfering substance. In a comparison with five other methods performed in four different laboratories, samples were collected to test the method performance over a wide range of urinary iodine values (0 …468Cite 

Low catalytic turnover of horseradish peroxidase in thiocyanate oxidation. Evidence for concurrent inactivation by cyanide generated through one-electron oxidation of thiocyanate.

Adak S, Mazumdar A, Banerjee RK.J Biol Chem. 1997 Apr 25;272(17):11049-56. doi: 10.1074/jbc.272.17.11049.PMID: 9110998 Free article.

The one-electron oxidation product of SCN- was identified by electron spin resonance spectroscopy as 5-5-dimethyl-1-pyrroline N-oxide adduct of the sulfur-centered thiocyanate radical (aN = 15.0 G and abetaH = 16.5 G). The inactivation of the enzyme in the presence of SCN- …469Cite 

Formation of reactive nitrogen species during peroxidase-catalyzed oxidation of nitrite. A potential additional mechanism of nitric oxide-dependent toxicity.

van der Vliet A, Eiserich JP, Halliwell B, Cross CE.J Biol Chem. 1997 Mar 21;272(12):7617-25. doi: 10.1074/jbc.272.12.7617.PMID: 9065416 Free article.

Peroxidase-catalyzed oxidation of NO2-, as indicated by phenolic nitration, was also observed in the presence of thiocyanate (SCN-), an alternative physiological substrate for mammalian peroxidases. Collectively, our results suggest that NO2-, at physiological or pathologi …470Cite 

Multicomponent spectroscopic investigations of salivary antioxidant consumption by an oral rinse preparation containing the stable free radical species chlorine dioxide (ClO2.).

Lynch E, Sheerin A, Claxson AW, Atherton MD, Rhodes CJ, Silwood CJ, Naughton DP, Grootveld M.Free Radic Res. 1997 Mar;26(3):209-34. doi: 10.3109/10715769709097801.PMID: 9161844

Experiments conducted on chemical model systems confirmed the oxidative decarboxylation of pyruvate by this oral rinse, and also demonstrated that urate, thiocyanate anion, and the amino acids cysteine and methionine (precursors to volatile sulphur compounds responsible fo …471Cite 

Myeloperoxidase: a key regulator of neutrophil oxidant production.

Kettle AJ, Winterbourn CC.Redox Rep. 1997 Feb;3(1):3-15. doi: 10.1080/13510002.1997.11747085.PMID: 27414766 Free article.

In addition to chlorination, myeloperoxidase displays several other activities. It readily oxidizes thiocyanate to hypothiocyanite, converts a myriad of organic substrates to reactive free radicals, and hydroxylates aromatic compounds. …472Cite 

Interaction of Escherichia coli cobalamin-dependent methionine synthase and its physiological partner flavodoxin: binding of flavodoxin leads to axial ligand dissociation from the cobalamin cofactor.

Hoover DM, Jarrett JT, Sands RH, Dunham WR, Ludwig ML, Matthews RG.Biochemistry. 1997 Jan 7;36(1):127-38. doi: 10.1021/bi961693s.PMID: 8993326473Cite 

Free radical reactions involving the angiotensin converting enzyme inhibitor captopril.

Forni LG, Hilton PJ, Willson RL, Cheeseman KH.Redox Rep. 1996 Dec;2(6):393-9. doi: 10.1080/13510002.1996.11747080.PMID: 27406674 Free article.

The results demonstrate that although captopril reacts rapidly with a number of free radicals, such as the hydroxyl radical (k = 5.1 10(9) dm(-3)mol(-1)s(-1)) and the thiocyanate radical anion (k = 1.3 10(7) dm(-3)mol(-1)s(-1)), it is not exceptional in this ability. …474Cite 

Electrochemical Properties of.

Gushikem Y, Peixoto CRM, Filho UPR, Kubota LT, Stadler E.J Colloid Interface Sci. 1996 Dec 1;184(1):236-40. doi: 10.1006/jcis.1996.0616.PMID: 8954659

The immobilized complex showed an electrochemical response due to the Ru(II)/Ru(III) redox couple. By substituting the coordinated water molecule in the adsorbed complex, the midpoint potentials shifted in the order (in mV) water, -290; thiocyanate, -200; pyridine, …475Cite 

Effects of pH and thiocyanate on hydrogen peroxide-induced evolution of molecular oxygen in human mixed saliva.

Nishioka T, Kimura M, Takahama U.Arch Oral Biol. 1996 Oct;41(10):911-7. doi: 10.1016/s0003-9969(96)00058-1.PMID: 9031698

The optimum pH was around pH 6. Sodium thiocyanate inhibited the oxygen evolution under acidic conditions in dialysed saliva, increasing the K(m) of hydrogen peroxide and decreasing the Vmax. …476Cite 

Competitive Substitution and Electron Transfer in Reactions between Haloamminegold(III) and Halocyanoaurate(III) Complexes and Thiocyanate.

Elmroth SK, Elding LI.Inorg Chem. 1996 Apr 10;35(8):2337-2342. doi: 10.1021/ic951126d.PMID: 11666433

Initial, rapid formation of mixed halide-thiocyanate complexes of gold(III) is followed by slower reduction to Au(CN)(2)(-) and Au(NH(3))(2)(+), respectively. …A transition state with an S-S interaction between attacking and coordinated thiocyanate is suggested fo …477Cite 

Evidence for more extensive deposits of epitopes of oxidized low density lipoprotein in aortas of young people with elevated serum thiocyanate levels. PDAY Research Group.

Scanlon CE, Berger B, Malcom G, Wissler RW.Atherosclerosis. 1996 Mar;121(1):23-33. doi: 10.1016/0021-9150(95)05672-6.PMID: 8678921

We know of no direct evidence linking oxidized LDL (oxLDL) in human arteries to increased atherosclerosis in individuals who show elevated serum thiocyanate levels (HST) as an indicator of recent smoking. We have studied arterial samples from smokers micromorphometrically …478Cite 

Characterization of sheep lacrimal-gland peroxidase and its major physiological electron donor.

Mazumdar A, Chatterjee R, Adak S, Ghosh A, Mondal C, Banerjee RK.Biochem J. 1996 Mar 1;314 ( Pt 2)(Pt 2):413-9. doi: 10.1042/bj3140413.PMID: 8670050 Free PMC article.

A plot of log Vmax against pH yields a sigmoidal curve consistent with a single ionizable group on the enzyme with a pK(a) value of 5.75, controlling thiocyanate oxidation. In a coupled system with the peroxidase, H2O2, SCN-, GSH, NADPH and glutathione reductase, peroxidas …479Cite 

The effect of three alpha-keto acids on 3-mercaptopyruvate sulfurtransferase activity.

Porter DW, Baskin SI.J Biochem Toxicol. 1996;11(1):45-50. doi: 10.1002/(SICI)1522-7146(1996)11:1<45::AID-JBT6>3.0.CO;2-V.PMID: 8806051

These observations add further support to the hypothesis that the mechanism of the alpha-keto acid antidotes is the nonenzymatic binding of cyanide, not stimulation of enzymes involved in the transsulfuration of cyanide to thiocyanate….480Cite 

Oxidation reactions of a bovine serum albumin-bilirubin complex. A pulse radiolysis study.

Adhikari S, Gopinathan C.Int J Radiat Biol. 1996 Jan;69(1):89-98. doi: 10.1080/095530096146219.PMID: 8601759481Cite 

Optimization of the covalent conjugating procedure (NaIO4) of horseradish peroxidase to antibodies for use in enzyme-linked immunosorbent assay.

Tsang VC, Greene RM, Pilcher JB.J Immunoassay. 1995 Nov;16(4):395-418. doi: 10.1080/15321819508013570.PMID: 8567986482Cite 

Inactivation of cholinesterase by ascorbic acid in the presence of cupric ions: a possible mechanism for the inactivation of an enzyme by the metal-catalyzed oxidation system.

Kanazawa H, Fujimoto S, Ohara A.Biol Pharm Bull. 1995 Sep;18(9):1179-83. doi: 10.1248/bpb.18.1179.PMID: 8845800 Free article.

A ternary complex involving the enzyme, Cu2+ and AsA is formed. This is followed by a redox reaction within the complex which generates a superoxide (.O2-) and hydrogen peroxide (H2O2). …Another role of H2O2 is the conversion of the reduced Cu+ within the complex to Cu2+ …483Cite 

Antioxidative activity of tetrahydrocurcuminoids.

Osawa T, Sugiyama Y, Inayoshi M, Kawakishi S.Biosci Biotechnol Biochem. 1995 Sep;59(9):1609-12. doi: 10.1271/bbb.59.1609.PMID: 8520105 Free article.484Cite 

Oxidative conversion of thiocyanate to cyanide by oxyhemoglobin during acid denaturation.

Seto Y.Arch Biochem Biophys. 1995 Aug 1;321(1):245-54. doi: 10.1006/abbi.1995.1392.PMID: 7639528

Human oxyhemoglobin (Hb-O2) converts thiocyanate to cyanide under acidic conditions, in a hemoglobin and thiocyanate concentration-dependent manner. …These data suggest that O2- generated during Hb-O2 denaturation and also a hydroperoxyl radical converted under ac …485Cite 

Mechanism of CO oxidation by carbon monoxide dehydrogenase from Clostridium thermoaceticum and its inhibition by anions.

Seravalli J, Kumar M, Lu WP, Ragsdale SW.Biochemistry. 1995 Jun 20;34(24):7879-88. doi: 10.1021/bi00024a012.PMID: 7794899

Thiocyanate acted as a mixed partial inhibitor with respect to CO. The inhibition constants were pH and temperature dependent. The pH dependencies of the inhibition constants gave pKa values of approximately 7.7. Binding of thiocyanate to the oxidized form of center …486Cite 

Thiocyanate, a plausible physiological electron donor of gastric peroxidase.

Das D, De PK, Banerjee RK.Biochem J. 1995 Jan 1;305 ( Pt 1)(Pt 1):59-64. doi: 10.1042/bj3050059.PMID: 7826354 Free PMC article.487Cite 

Concentrations of thiocyanate and hypothiocyanite in the saliva of young adults.

Jalil RA.J Nihon Univ Sch Dent. 1994 Dec;36(4):254-60. doi: 10.2334/josnusd1959.36.254.PMID: 7869127

The study was conducted to determine thiocyanate (SCN-) and hypothiocyanite (OSCN-) concentrations in resting (RWS) and stimulated whole saliva (SWS) and stimulated parotid saliva (SPS) of 20 healthy young adults aged 21-29 y. …488Cite 

Transport of ebselen in plasma and its transfer to binding sites in the hepatocyte.

Wagner G, Schuch G, Akerboom TP, Sies H.Biochem Pharmacol. 1994 Sep 15;48(6):1137-44. doi: 10.1016/0006-2952(94)90150-3.PMID: 7945407

Quantitative release of ebselen from its BSA complex was only achieved by the combined action of reductant, notably 2-mercaptoethanol, and guanidine thiocyanate, suggesting that ebselen interacts with proteins by covalent Se-S bonds as well as by ionic charge interactions. …489Cite 

Effects of isothiocyanate alkyl chain-length on hamster liver cytochrome P-450 activity.

Hamilton SM, Zhang Z, Teel RW.Cancer Lett. 1994 Jul 29;82(2):217-24. doi: 10.1016/0304-3835(94)90015-9.PMID: 8050094490Cite 

Effect of radical scavengers on the inactivation of papain by ascorbic acid in the presence of cupric ions.

Kanazawa H, Fujimoto S, Ohara A.Biol Pharm Bull. 1994 Apr;17(4):476-81. doi: 10.1248/bpb.17.476.PMID: 8069251 Free article.

The oxidation of AsA was unaffected by catalase. Both thiourea and sodium thiocyanate completely protected the enzyme from inactivation, while AsA was partially oxidized only in the initial stage. …The present results suggest that H2O2 serves as a source of secondary, hi …491Cite 

Antibacterial activity of hydrogen peroxide and the lactoperoxidase-hydrogen peroxide-thiocyanate system against oral streptococci.

Thomas EL, Milligan TW, Joyner RE, Jefferson MM.Infect Immun. 1994 Feb;62(2):529-35. doi: 10.1128/iai.62.2.529-535.1994.PMID: 8300211 Free PMC article.

In secreted fluids, the enzyme lactoperoxidase (LP) catalyzes the oxidation of thiocyanate ion (SCN-) by hydrogen peroxide (H2O2), producing the weak oxidizing agent hypothiocyanite (OSCN-), which has bacteriostatic activity. However, H2O2 has antibacterial activity in the …492Cite 

1H- and 15N-NMR study of the binding of thiocyanate to chemically modified horseradish peroxidase and involvement of salt bridge.

Modi S, Behere DV, Mitra S.Biochim Biophys Acta. 1994 Jan 11;1204(1):14-8. doi: 10.1016/0167-4838(94)90026-4.PMID: 8305470

The chemical modification of native horseradish peroxidase (HRP) has been carried out by esterification of the heme propionic group. 15N- and 1H-NMR studies on binding of thiocyanate ion to chemically modified HRP have been utilized to demonstrate the existence of salt bri …493Cite 

Release of elements due to electrochemical corrosion of dental amalgam.

Olsson S, Berglund A, Bergman M.J Dent Res. 1994 Jan;73(1):33-43. doi: 10.1177/00220345940730010501.PMID: 8294616494Cite 

[Biological oxidation of a sulfur atom in single-carbon and organic compounds].

Sorokin DIu.Mikrobiologiia. 1993 Nov-Dec;62(6):981-93.PMID: 8114647 Review. Russian.495Cite 

Ferredoxin binding site on ferredoxin: NADP+ reductase. Differential chemical modification of free and ferredoxin-bound enzyme.

Jelesarov I, De Pascalis AR, Koppenol WH, Hirasawa M, Knaff DB, Bosshard HR.Eur J Biochem. 1993 Aug 15;216(1):57-66. doi: 10.1111/j.1432-1033.1993.tb18116.x.PMID: 8365417 Free article.496Cite 

Structure-function relations in photosystem II. Effects of temperature and chaotropic agents on the period four oscillation of flash-induced oxygen evolution.

Messinger J, Schröder WP, Renger G.Biochemistry. 1993 Aug 3;32(30):7658-68. doi: 10.1021/bi00081a009.PMID: 8347576497Cite 

Cigarette-smoking, birthweight, thiocyanate and fluorescent lipid-peroxidation products in maternal and cord plasma.

Pré J, Colau JC, Vassy R.Clin Chim Acta. 1993 Jun 16;215(2):221-6. doi: 10.1016/0009-8981(93)90128-q.PMID: 8403437 No abstract available.498Cite 

Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice.

Guo Z, Smith TJ, Wang E, Eklind KI, Chung FL, Yang CS.Carcinogenesis. 1993 Jun;14(6):1167-73. doi: 10.1093/carcin/14.6.1167.PMID: 8508504499Cite 

Fluoride inhibition of SCN- and Cl-peroxidase activities in whole saliva and of recombinant myeloperoxidase. Influence of pH and hydrogen peroxide concentration.

van den Abbeele A, Pourtois M, Courtois P.J Biol Buccale. 1992 Dec;20(4):219-24.PMID: 1339090

Fluoride (F-) inhibition of peroxidase activity in whole saliva and of recombinant human myeloperoxidase was investigated using thiocyanate (SCN-) and chloride (Cl-) as substrates. At pH 5.5, SCN(-)-linked activity in whole saliva reduced to < 40% of its initial value a…500Cite 

Susceptibility of Candida albicans to peroxidase-catalyzed oxidation products of thiocyanate, iodide and bromide.

Majerus PM, Courtois PA.J Biol Buccale. 1992 Dec;20(4):241-5.PMID: 1306188

The survival rate of Candida blastospores after a 30 min exposure to lactoperoxidase system ranged from 79 to 105% in the presence of 615 microM thiocyanate, from 56 to 88% in the presence of 345 microM bromide and from 0 to 4% in the presence of 250 microM iodide. …Neve …501Cite 

Lactoperoxidase-catalyzed oxidation of thiocyanate ion: a carbon-13 nuclear magnetic resonance study of the oxidation products.

Pollock JR, Goff HM.Biochim Biophys Acta. 1992 Oct 20;1159(3):279-85. doi: 10.1016/0167-4838(92)90057-k.PMID: 1390933

Products formed from the lactoperoxidase (LPO) catalyzed oxidation of thiocyanate ion (SCN-) with hydrogen peroxide (H2O2) have been studied by 13C-NMR at pH 6 and pH 7. …502Cite 

Free radical generation and coupled thiol oxidation by lactoperoxidase/SCN-/H2O2.

Løvaas E.Free Radic Biol Med. 1992 Sep;13(3):187-95. doi: 10.1016/0891-5849(92)90014-8.PMID: 1324202

The lactoperoxidase-catalyzed oxidation of glutathione (GSH) and thiocyanate (SCN-) was studied. Oxidation of SCN- was recorded by ultraviolet spectroscopy and by electron spin resonance (ESR). …503Cite 

Lethal oxidative damage to human immunodeficiency virus by human recombinant myeloperoxidase.

Moguilevsky N, Steens M, Thiriart C, Prieels JP, Thiry L, Bollen A.FEBS Lett. 1992 May 18;302(3):209-12. doi: 10.1016/0014-5793(92)80442-j.PMID: 1318224 Free article.

In the presence of a hydrogen peroxide generating system (glucose and glucose oxidase) and sodium thiocyanate, the recombinant enzyme inhibited virus-induced syncytium formation and viral replication without causing any cytopathic effects on SupT1 reporter cells. …504Cite 

Lysozyme enhances the inhibitory effects of the peroxidase system on glucose metabolism of Streptococcus mutans.

Lenander-Lumikari M, Månsson-Rahemtulla B, Rahemtulla F.J Dent Res. 1992 Mar;71(3):484-90. doi: 10.1177/00220345920710031201.PMID: 1573081505Cite 

Determination of cysteine plus half-cystine in protein and peptide hydrolysates: use of dithiodiglycolic acid and phenylisothiocyanate derivatization.

Hoogerheide JG, Campbell CM.Anal Biochem. 1992 Feb 14;201(1):146-51. doi: 10.1016/0003-2697(92)90187-c.PMID: 1621953

The determination requires no additional sample handling, oxidation, reduction, alkylation, or desalting. Samples containing cystine are treated in the same manner as those containing cysteine. …506Cite 

Studies on the lactoperoxidase system: reaction kinetics and antibacterial activity using two methods for hydrogen peroxide generation.

Dionysius DA, Grieve PA, Vos AC.J Appl Bacteriol. 1992 Feb;72(2):146-53. doi: 10.1111/j.1365-2672.1992.tb01816.x.PMID: 1556038

Components of the lactoperoxidase system were measured during incubation in Isosensitest broth, with enzymatic (glucose oxidase, GO) or chemical (sodium carbonate peroxyhydrate, SCP) means to generate H2O2. When low levels of thiocyanate (SCN-) were used in the GO system, …507Cite 

[The addition of potassium rhodanide to artificial saliva in electrochemical corrosion research].

Borchmann M, Borchmann A.Schweiz Monatsschr Zahnmed. 1992;102(2):184-7.PMID: 1631523 German.

Polarization curves of five dental alloys and pure platinum were made in artificial saliva with and without potassium-thiocyanate. From 400 mV (SCE) the noble alloys show a current rise. The reason for this current rise not corrosion, but a redox reaction of the pot …508Cite 

Horseradish peroxidase catalyzed oxidation of thiocyanate by hydrogen peroxide: comparison with lactoperoxidase-catalysed oxidation and role of distal histidine.

Modi S, Behere DV, Mitra S.Biochim Biophys Acta. 1991 Oct 11;1080(1):45-50. doi: 10.1016/0167-4838(91)90110-l.PMID: 1932081

Horseradish peroxidase-catalysed oxidation of thiocyanate by hydrogen peroxide has been studied by 15N-NMR and optical spectroscopy at different concentrations of thiocyanate and hydrogen peroxide and at different pH values. …Chem. 264, 19677-19684), the binding o …509Cite 

Peptide maps at picomolar levels obtained by reversed-phase high-performance liquid chromatography and pre-column derivatization with phenyl isothiocyanate. Microsequencing of Phenylthiocarbamyl Peptides.

Colilla FJ, Yadav SP, Brew K, Mendez E.J Chromatogr. 1991 Jul 12;548(1-2):303-10. doi: 10.1016/s0021-9673(01)88612-x.PMID: 1939428510Cite 

Catalytic determination of ultratrace amounts of ruthenium with oscillopolarographic detection.

Zhi-Liang J.Talanta. 1991 Jun;38(6):621-5. doi: 10.1016/0039-9140(91)80145-p.PMID: 18965194

A very sensitive and selective catalytic reaction-oscillopolarographic method for the determination of Ru down to 3 ng/l. is described, based on the Ru(III)-catalysed redox reaction of Methyl Red and potassium periodate in hydrochloric acid medium. Potassium thiocyanate …511Cite 

Thiocyanate is the major substrate for eosinophil peroxidase in physiologic fluids. Implications for cytotoxicity.

Slungaard A, Mahoney JR Jr.J Biol Chem. 1991 Mar 15;266(8):4903-10.PMID: 2002037 Free article.512Cite 

Altered polymorphonuclear leukocyte Fc gamma R expression contributes to decreased candicidal activity during intraabdominal sepsis.

Simms HH, D’Amico R, Monfils P, Burchard KW.J Lab Clin Med. 1991 Mar;117(3):241-9.PMID: 1825837513Cite 

8-thiocyanatoflavins as active-site probes for flavoproteins.

Macheroux P, Massey V.Biochemistry. 1991 Jan 15;30(2):456-64. doi: 10.1021/bi00216a022.PMID: 1670991514Cite 

Lactoperoxidase-catalyzed oxidation of thiocyanate by hydrogen peroxide: 15N nuclear magnetic resonance and optical spectral studies.

Modi S, Deodhar SS, Behere DV, Mitra S.Biochemistry. 1991 Jan 8;30(1):118-24. doi: 10.1021/bi00215a018.PMID: 1988011

To establish the agent(s) responsible for the activity of the lactoperoxidase (LPO)/SCN-/H2O2 system, the oxidation of thiocyanate with hydrogen peroxide, catalyzed by lactoperoxidase, has been studied by 15N NMR and optical spectroscopy at different concentrations of t …515Cite 

Cyanide liberation and oxidative stress by organothiocyanates, organonitriles and nitroprusside in isolated hepatocytes.

Elguindi S, O’Brien PJ.Adv Exp Med Biol. 1991;283:271-4. doi: 10.1007/978-1-4684-5877-0_30.PMID: 2068995 No abstract available.516Cite 

Controlled-potential electrolysis of bulk solutions at a modified electrode: application to oxidations of cysteine, cystine, methionine, and thiocyanate.

Cox JA, Gray TJ.Anal Chem. 1990 Dec 15;62(24):2742-4. doi: 10.1021/ac00223a018.PMID: 2096738 No abstract available.517Cite 

One interferon gamma receptor binds one interferon gamma dimer.

Fountoulakis M, Juranville JF, Maris A, Ozmen L, Garotta G.J Biol Chem. 1990 Nov 15;265(32):19758-67.PMID: 2147181 Free article.518Cite 

Separation and detection of phospholipid hydroperoxides in the low nanomolar range by a high performance liquid chromatography/ironthiocyanate assay.

Mullertz A, Schmedes A, Hølmer G.Lipids. 1990 Jul;25(7):415-8. doi: 10.1007/BF02537987.PMID: 2395422519Cite 

Deoxygenation-induced cation fluxes in sickle cells: II. Inhibition by stilbene disulfonates.

Joiner CH.Blood. 1990 Jul 1;76(1):212-20.PMID: 2364172 Free article.520Cite 

Abolition of herpes simplex cytopathic effect after treatment with peroxidase generated hypothiocyanite.

Courtois P, van Beers D, de Foor M, Mandelbaum IM, Pourtois M.J Biol Buccale. 1990 Jun;18(2):71-4.PMID: 2170348

HSV1 suspensions were pre-incubated in a lactoperoxidase thiocyanate oxidizing system before inoculation in MRC5 fibroblast cultures. This pre-treatment could either delay or even abolish the HSV1 cytopathic potentiality. …521Cite 

The activation of gold complexes by cyanide produced by polymorphonuclear leukocytes–I. The effects of aurocyanide on the oxidative burst of polymorphonuclear leukocytes.

Rudkowski R, Graham GG, Champion GD, Ziegler JB.Biochem Pharmacol. 1990 Jun 1;39(11):1687-95. doi: 10.1016/0006-2952(90)90112-x.PMID: 2160817

It has been suggested that the antiarthritic gold complex, aurothiomalate (Autm), is activated by its conversion to aurocyanide by polymorphonuclear leukocytes (PMN) which generate cyanide from thiocyanate. In an examination of this hypothesis, a study has been conducted o …522Cite 

The mechanism of action of synthetic antithyroid drugs: iodine complexation during oxidation of iodide.

Raby C, Lagorce JF, Jambut-Absil AC, Buxeraud J, Catanzano G.Endocrinology. 1990 Mar;126(3):1683-91. doi: 10.1210/endo-126-3-1683.PMID: 1689656

A number of compounds of pharmaceutical importance from a variety of chemical families, including thiocyanates, isothiocyanates, thiourea and derivatives, imidazoles, and various amines, were found to form charge transfer complexes with iodine. …523Cite 

Assay of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase.

Bozeman PM, Learn DB, Thomas EL.J Immunol Methods. 1990 Jan 24;126(1):125-33. doi: 10.1016/0022-1759(90)90020-v.PMID: 2154520

MPO catalyzes the oxidation of chloride to hypochlorus acid (HOCl), which also oxidized TMB, but chloride up to 20 mM had little effect on the assay. Both MPO and EPO catalyze thiocyanate oxidation, but the product (HOSCN) was a poor oxidant for TMB, and thiocyanate …524Cite 

Cytotoxic properties of salivary oxidants.

Grisham MB, Ryan EM.Am J Physiol. 1990 Jan;258(1 Pt 1):C115-21. doi: 10.1152/ajpcell.1990.258.1.C115.PMID: 2154109

Salivary peroxidase and to a lesser extent myeloperoxidase are present in significant concentrations in saliva and catalyze the oxidation of thiocyanate anion (SCN-) by H2O2 to yield the potent oxidants hypothiocyanous acid (HOSCN) and its conjugate base hypothiocyanite an …525Cite 

Yeast alcohol dehydrogenase bound to membranes: surface and microenvironment effects on activity and stability.

Kennedy CL, Domach MM.Biotechnol Prog. 1990 Jan-Feb;6(1):41-7. doi: 10.1021/bp00001a006.PMID: 1369253526Cite 

Precolumn phenylisothiocyanate derivatization and liquid chromatography of amino acids in food.

Hagen SR, Frost B, Augustin J.J Assoc Off Anal Chem. 1989 Nov-Dec;72(6):912-6.PMID: 2592313527Cite 

A pulse radiolysis investigation of the oxidation of indolic melanin precursors: evidence for indolequinones and subsequent intermediates.

Lambert C, Chacon JN, Chedekel MR, Land EJ, Riley PA, Thompson A, Truscott TG.Biochim Biophys Acta. 1989 Oct 13;993(1):12-20. doi: 10.1016/0304-4165(89)90136-0.PMID: 2804118528Cite 

Lipid peroxidation in acrylonitrile-treated rats, evidenced by elevated ethane production.

Ivanov V, Rahier J, Lauwerys R.J Appl Toxicol. 1989 Oct;9(5):353-8. doi: 10.1002/jat.2550090512.PMID: 2592735

A dose of sodium cyanide (2.5 mg kg-1 i.p.) which leads to a urinary excretion of thiocyanate similar to that found after the intraperitoneal administration of 25 mg kg-1 acrylonitrile, does not stimulate ethane production. …529Cite 

Purification and properties of the intact P-700 and Fx-containing Photosystem I core protein.

Parrett KG, Mehari T, Warren PG, Golbeck JH.Biochim Biophys Acta. 1989 Feb 28;973(2):324-32. doi: 10.1016/s0005-2728(89)80439-6.PMID: 2537101530Cite 

Auto-oxidation of Lingula unguis and Siphonosoma cumanense hemerythrins induced by some perturbants.

Tambo F, Ichimura K, Fuseya M, Takahashi S, Yamamura T, Kihara H, Satake K.Biochem Int. 1989 Feb;18(2):311-7.PMID: 2764951

In the presence of urea, there were no drastic increases in auto-oxidation rates for the three proteins. In contrast, thiocyanate and laurate enhanced the auto-oxidation rates remarkably. In the presence of thiol reagents such as PCMB and NEM, auto-oxidation rates were enh …531Cite 

Proton translocation coupled to the oxidation of carbon monoxide to CO2 and H2 in Methanosarcina barkeri.

Bott M, Thauer RK.Eur J Biochem. 1989 Feb 1;179(2):469-72. doi: 10.1111/j.1432-1033.1989.tb14576.x.PMID: 2537211 Free article.532Cite 

Nitrous oxide reductase from Pseudomonas stutzeri. Redox properties and spectroscopic characterization of different forms of the multicopper enzyme.

Riester J, Zumft WG, Kroneck PM.Eur J Biochem. 1989 Jan 2;178(3):751-62. doi: 10.1111/j.1432-1033.1989.tb14506.x.PMID: 2536326 Free article.

The oxidation–reduction and spectroscopic properties of various forms of nitrous oxide reductase from Pseudomonas stutzeri were investigated. …Marked effects were also obtained for the exogenous ligands nitrite, azide, cyanate and thiocyanate.(ABSTRACT TRUN …533Cite 

Superoxide anion measurement by sulfonated phenyl isothiocyanate cytochrome c.

Morel F, Dianoux AC, Vignais PV.Biochem Biophys Res Commun. 1988 Nov 15;156(3):1175-81. doi: 10.1016/s0006-291x(88)80756-3.PMID: 2847727534Cite 

Determination of sulphide by anion-exchange with lead iodate.

Verma KK, Gupta D, Sanghi SK, Jain A.Talanta. 1988 Nov;35(11):917-9. doi: 10.1016/0039-9140(88)80215-7.PMID: 18964645

Chloride, bromide, iodide, fluoride, oxalate, sulphate, thiocyanate and phosphate do not interfere. Thiosulphate, sulphite, nitrite and thiols do not give an anion-exchange reaction but do interfere in the redox reaction of iodate with acidified iodide. …535Cite 

Superoxide dismutase and catalase conjugated to polyethylene glycol increases endothelial enzyme activity and oxidant resistance.

Beckman JS, Minor RL Jr, White CW, Repine JE, Rosen GM, Freeman BA.J Biol Chem. 1988 May 15;263(14):6884-92.PMID: 3129432 Free article.536Cite 

Multidimensional diffusion modes and collision frequencies of cytochrome c with its redox partners.

Gupte SS, Hackenbrock CR.J Biol Chem. 1988 Apr 15;263(11):5241-7.PMID: 2833501 Free article.

Furthermore, as ionic strength is raised from zero to 150 mM, the cytochrome ckd for the inner membrane increases, its mean occupancy time on the inner membrane to collide with a redox partner (tau) decreases, and its diffusion-based collision frequencies with its redox …537Cite 

Determination of oxidizable inorganic anions by high-performance liquid chromatography with fluorescence detection and application to the determination of salivary nitrite and thiocyanate and serum thiocyanate.

Tanabe S, Kitahara M, Nawata M, Kawanabe K.J Chromatogr. 1988 Jan 22;424(1):29-37. doi: 10.1016/s0378-4347(00)81073-7.PMID: 3366836

A sensitive method for the simultaneous determination of oxidizable inorganic anions (sulphide, thiocyanate, thiosulphate and nitrite) was developed by use of high-performance liquid chromatography and fluorimetric detection based on the formation of fluorescent cerium(III …538Cite 

Steady-state kinetics of thiocyanate oxidation catalyzed by human salivary peroxidase.

Pruitt KM, Mansson-Rahemtulla B, Baldone DC, Rahemtulla F.Biochemistry. 1988 Jan 12;27(1):240-5. doi: 10.1021/bi00401a036.PMID: 3349029

A steady-state kinetic analysis was made of thiocyanate (SCN-) oxidation catalyzed by human peroxidase (SPO) isolated from parotid saliva. …The pH-independent second-order rate constants (k4) for the oxidation of thiocyanate by compound I were estimated to be 5 X …539Cite 

Generation of a membrane potential by electron transport in plasmalemma-enriched vesicles of cotton and radish.

Hassidim M, Rubinstein B, Lerner HR, Reinhold L.Plant Physiol. 1987 Dec;85(4):872-5. doi: 10.1104/pp.85.4.872.PMID: 16665822 Free PMC article.

When 100 millimolar ascorbate was added to the grinding medium, the addition of ferricyanide to either preparation led to an inside positive membrane potential as measured by the accumulation of thiocyanate. It is suggested that electrons from ascorbate were being transpor …540Cite 

Iron autoxidation in Mops and Hepes buffers.

Tadolini B.Free Radic Res Commun. 1987;4(3):149-60. doi: 10.3109/10715768709088100.PMID: 3148493

The iron product of the oxidative reaction differs from Fe3+ in its absorption spectrum and its low reactivity with thiocyanate. Similar results are obtained when iron autoxidation is studied in unbuffered solutions brought to alkaline pH with NaOH. …The iron product rea …541Cite 

Oxidation of chloride and thiocyanate by isolated leukocytes.

Thomas EL, Fishman M.J Biol Chem. 1986 Jul 25;261(21):9694-702.PMID: 3015901 Free article.

Peroxidase-catalyzed oxidation of chloride (Cl-) and thiocyanate (SCN-) was studied using neutrophils from human blood and eosinophils and macrophages from rat peritoneal exudates. …542Cite 

The presence of desulfo xanthine dehydrogenase in purified and crude enzyme preparations from rat liver.

Ikegami T, Nishino T.Arch Biochem Biophys. 1986 Jun;247(2):254-60. doi: 10.1016/0003-9861(86)90582-5.PMID: 3459393

The enzyme was inactivated by cyanide, which caused the release of a sulfur atom from the molybdenum center as thiocyanate. The amount of thiocyanate released was almost in parallel with the initial specific activity. …543Cite 

Detection of disulphide bonds and localization of interchain linkages in the third (C3) and the fourth (C4) components of human complement.

Janatova J.Biochem J. 1986 Feb 1;233(3):819-25. doi: 10.1042/bj2330819.PMID: 3707529 Free PMC article.544Cite 

Production of nitrite ions from trinitrophenyl myosin and from trinitrophenyl subfragment-1.

Nakata S, Eiki T, Tanaka N, Koyama T, Tsukui H, Watanabe S.J Biochem. 1986 Jan;99(1):27-32. doi: 10.1093/oxfordjournals.jbchem.a135470.PMID: 3957895 Free article.545Cite 

Formation of HCN and its chlorination to ClCN by stimulated human neutrophils–2. Oxidation of thiocyanate as a source of HCN.

Stelmaszyńska T.Int J Biochem. 1986;18(12):1107-14. doi: 10.1016/0020-711x(86)90084-4.PMID: 3028884

Leucocytes challenged by Staphylococcus epidermidis or stimulated by phorbol myristate acetate (PMA) produce cyanide from thiocyanate. The amount of H14CN formed depends on KS14CN concentration and is enhanced by pretreatment of phagocytosed bacteria with penicillin or by …546Cite 

Determination of methionine sulfoxide in proteins: comparison of a gas-chromatographic and electrophoretic method.

Amiconi G, Ascoli F, Concetti A, Matarese M, Verzili D, Brunori M.J Biochem Biophys Methods. 1985 Oct;11(4-5):241-9. doi: 10.1016/0165-022x(85)90006-5.PMID: 4067174

Both methods are based on prior treatment with cyanogen bromide, which attacks methionines (but not the sulfoxide derivative) with the resultant formation of methyl thiocyanate and peptides. The amount of methyl thiocyanate is determined quantitatively by gas chroma …547Cite 

pH-dependent fluoride inhibition of peroxidase activity.

Thibodeau EA, Bowen WH, Marquis RE.J Dent Res. 1985 Oct;64(10):1211-3. doi: 10.1177/00220345850640100601.PMID: 3861651

Fluoride inhibition of lactoperoxidase occurred with all reductants tested, including thiocyanate, iodide, and guaiacol. Fluoride concentrations for 50% inhibition of enzymatic activity with iodide as reductant were: less than 0.05 mM at a pH value of 4.0, 0.3 mM at 5.0, 4 …548Cite 

Studies of pyridine nucleotide oxidizing enzymes from human neutrophils.

Mackler B, Person R, Davis KA, Ochs H.Biochem Int. 1985 Sep;11(3):319-25.PMID: 3933511

Treatment of preparations of R2 with deoxycholate or potassium thiocyanate separated the two enzymes yielding particulate preparations with only NADPH oxidase or NADH cytochrome c reductase activity, respectively….549Cite 

The electrochemical H+ gradient in the yeast Rhodotorula glutinis.

Höfer M, Nicolay K, Robillard G.J Bioenerg Biomembr. 1985 Jun;17(3):175-82. doi: 10.1007/BF00751060.PMID: 4040135

The membrane potential, delta psi, was measured by steady-state distribution of the hydrophobic ions, tetraphenylphosphonium (TPP+) for negative delta psi above pH0 4.5, and thiocyanate (SCN-) for positive delta psi below pH0 4.5. The chemical gradient of H+ was determined …550Cite 

Functional role of cysteinyl residues in tryptophanase.

Nihira T, Yasuda T, Kakizono T, Taguchi H, Ichikawa M, Toraya T, Fukui S.Eur J Biochem. 1985 May 15;149(1):129-33. doi: 10.1111/j.1432-1033.1985.tb08902.x.PMID: 3888623 Free article.551Cite 

NAD-coupled enzymatic oxidation of O-ethyl O-p-nitrophenyl phenylphosphonothioate (EPN) to its oxygen analog with liver microsomes of rats.

Sugiyama S, Igarashi T, Ueno K, Satoh T, Kitagawa H.Jpn J Pharmacol. 1985 Mar;37(3):245-52. doi: 10.1254/jjp.37.245.PMID: 3999477 Free article.

This potentiation of the anti-CEase action of EPN by NAD was significantly inhibited by addition of SKF 525-A or potassium thiocyanate (KSCN); and a simultaneous decrease in cytochrome P-450 contents were also observed. …552Cite 

In vivo and in vitro release of cyanide from neurotoxic aminonitriles.

Froines JR, Postlethwait EM, LaFuente EJ, Liu WC.J Toxicol Environ Health. 1985;16(3-4):449-60. doi: 10.1080/15287398509530754.PMID: 4087311

Investigation of cyanide released as urinary thiocyanate following ip aminonitrile administration to rats was also measured. The yield of cyanide in the in vivo study, as measured by the mole percent of administered dose, was greatest from dimethylaminonitrile (DMAA), foll …553Cite 

Determination of rhodanese activity by tetrazolium reduction.

Cannella C, Berni R, Ricci G.Anal Biochem. 1984 Oct;142(1):159-62. doi: 10.1016/0003-2697(84)90531-1.PMID: 6097140

The present method is more sensitive than the usual procedure based on the colorimetric determination of thiocyanate. Furthermore, the color developed by nitroblue tetrazolium reduction affords a straightforward means to locate rhodanese activity in polyacrylamide gels….554Cite 

Voltammetric study of the redox behaviour of the Hg(II)/Hg(I)/Hg system at a rotating metal-ring/glassy-carbon disc electrode.

Kiekens P, Temmerman E, Verbeek F.Talanta. 1984 Sep;31(9):693-701. doi: 10.1016/0039-9140(84)80152-6.PMID: 18963681

When an appropriate amount of a cation such as cadmium(II) or copper(II) is added to the test solution, mercury down to 2 x 10(-9)M (0.4 ng ml ) can be determined in acidified thiocyanate electrolyte with a relative standard deviation of about 22%….555Cite 

On the effects of thiocyanate and venturicidin on respiration-driven proton translocation in Paracoccus denitrificans.

Hitchens GD, Kell DB.Biochim Biophys Acta. 1984 Jul 27;766(1):222-32. doi: 10.1016/0005-2728(84)90235-4.PMID: 6743650

This observation militates further against arguments in which (a) a non-ohmic leak of protons from the bulk aqueous phase might alone be the cause of the low—-H+/O ratios observed in the absence of SCN-, and (b) in which there might be a delta p-dependent change (‘redox …556Cite 

A comparison of the reactions of cytochrome c oxidase, cytochrome c and azurin with Cr2+ ions.

Jones GD, Wilson MT.J Inorg Biochem. 1984 Jun;21(2):147-58. doi: 10.1016/0162-0134(84)85047-3.PMID: 6330295

The behavior of the electron acceptor site of cytochrome c oxidase stands in contrast to that of the other redox proteins with regard to the effects of added anions and we suggest that this reflects the more buried nature of this site in the complex enzyme….557Cite 

Sampling and analysing mixtures of sulphate, sulphite, thiosulphate and polythionate.

Moses CO, Nordstrom DK, Mills AL.Talanta. 1984 May;31(5):331-9. doi: 10.1016/0039-9140(84)80092-2.PMID: 18963606

Interpreting the redox chemistry of sulphur in aqueous systems requires the analysis of mixtures of various sulphoxy anions. …Methods based on ion chromatography have been developed for the direct determination of SO(2-)(4), SO(2-)(3), S(2)O(2-)(3), and SCN(-). The deter …558Cite 

Selective chemical modification of a functionally linked lysine in cytochrome P-450 LM2.

Bernhardt R, Makower A, Jänig GR, Ruckpaul K.Biochim Biophys Acta. 1984 Mar 29;785(3):186-90. doi: 10.1016/0167-4838(84)90143-2.PMID: 6422989559Cite 

Effect of injected glucagon or fatty acids on mitochondrial ATPase.

López-Moratalla N, Funes T, Garrido B, Fernández de Manzanos T, Santiago E.Arch Biochem Biophys. 1984 Feb 15;229(1):194-201. doi: 10.1016/0003-9861(84)90144-9.PMID: 6322687

These results suggest that the modification of the properties of mitochondrial ATPase induced by glucagon or fatty acids might be mediated by a change in the mitochondrial redox state….560Cite 

Cystine antagonism of the antibacterial action of lactoperoxidase-thiocyanate-hydrogen peroxide on Streptococcus agalactiae.

Mickelson MN, Anderson AJ.Appl Environ Microbiol. 1984 Feb;47(2):338-42. doi: 10.1128/aem.47.2.338-342.1984.PMID: 6370135 Free PMC article.

Cystine reduction in Streptococcus agalactiae, resulting in sulfhydryl formation, may account for antagonism of the antibacterial effect of lactoperoxidase-thiocyanate-hydrogen peroxide when cystine is present in excess of the amount needed for maximum growth. …The infor …561Cite 

[Molecular mechanisms of the biological action of nitriles].

Sukhomlinov BF, Trikulenko AV.Farmakol Toksikol. 1984 Jan-Feb;47(1):123-6.PMID: 6705900 Russian. No abstract available.562Cite 

Reduction of fading of fluorescent reaction product for microphotometric quantitation.

Picciolo GL, Kaplan DS.Adv Appl Microbiol. 1984;30:197-234. doi: 10.1016/s0065-2164(08)70056-x.PMID: 6442533 Review. No abstract available.563Cite 

Pathway of oxidation of pyruvic oxime by a heterotrophic nitrifier of the genus Alcaligenes: evidence against hydrolysis to pyruvate and hydroxylamine.

Castignetti D, Petithory JR, Hollocher TC.Arch Biochem Biophys. 1983 Jul 15;224(2):587-93. doi: 10.1016/0003-9861(83)90246-1.PMID: 6307157

Major differences were observed between pyruvic oxime and one or both of the other reductants with regard to growth yield, rates of reductant uptake, rates of oxygen uptake, sensitivity of their oxidations to inhibition by thiocyanate, and performance in reductant pulse ex …564Cite 

Metabolism of acrylonitrile by isolated rat hepatocytes.

Geiger LE, Hogy LL, Guengerich FP.Cancer Res. 1983 Jul;43(7):3080-7.PMID: 6850616

Cyanide, resulting from hydrolysis of 2-cyanoethylene oxide, appeared to be completely converted to thiocyanate, which was identified by gel exclusion chromatography and mass spectrometry of the methyl derivative. The concentration of thiocyanate formed was directly …565Cite 

Detection of the hypothiocyanite (OSCN-) ion in human parotid saliva and the effect of pH on OSCN- generation in the salivary peroxidase antimicrobial system.

Pruitt KM, Mansson-Rahemtulla B, Tenovuo J.Arch Oral Biol. 1983;28(6):517-25. doi: 10.1016/0003-9969(83)90184-x.PMID: 6578767566Cite 

The peroxidation of thiocyanate catalysed by myeloperoxidase and lactoperoxidase.

Wever R, Kast WM, Kasinoedin JH, Boelens R.Biochim Biophys Acta. 1982 Dec 20;709(2):212-9. doi: 10.1016/0167-4838(82)90463-0.PMID: 6295491567Cite 

The role of lactoperoxidase-H2O2 compounds in the catalysis of thyroglobulin iodination and thyroid hormone synthesis.

Courtin F, Deme D, Virion A, Michot JL, Pommier J, Nunez J.Eur J Biochem. 1982 Jun;124(3):603-9. doi: 10.1111/j.1432-1033.1982.tb06637.x.PMID: 7106111 Free article. No abstract available.568Cite 

Quantitative study of the reaction between quinones and iron(II) in phosphoric acid medium.

Murty NK, Dakshina Murty PM.Talanta. 1982 Mar;29(3):234-6. doi: 10.1016/0039-9140(82)80101-x.PMID: 18963119

A simple method is described for the determination of some quinones with ammonium iron(II) sulphate, by titration potentiometrically or with cacotheline, Methylene Blue, Methylene Green, thionine, Toluidine Blue, Azure A, Azure C or Azure-2-eosin as redox indicators. The r …569Cite 

Lactoperoxidase-catalyzed oxidation of thiocyanate: polarographic study of the oxidation products.

Pruitt KM, Tenovuo J, Andrews RW, McKane T.Biochemistry. 1982 Feb 2;21(3):562-7. doi: 10.1021/bi00532a023.PMID: 7066307

The lactoperoxidase-catalyzed oxidation of thiocyanate (SCN-) was studied by two different polarographic techniques: direct current polarography and linear sweep voltammetry. …570Cite 

[Determination of the iodine content in food products using the nitrite-rhodanide method].

Proskuriakova GV, Eremin IuN.Vopr Pitan. 1982 Jan-Feb;(1):59-61.PMID: 7072183 Russian.571Cite 

Proton translocation associated with nitrite respiration in Desulfovibrio desulfuricans.

Steenkamp DJ, Peck HD Jr.J Biol Chem. 1981 Jun 10;256(11):5450-8.PMID: 7016854 Free article.572Cite 

Lactoperoxidase-catalyzed oxidation of thiocyanate: equilibria between oxidized forms of thiocyanate.

Thomas EL.Biochemistry. 1981 May 26;20(11):3273-80. doi: 10.1021/bi00514a045.PMID: 7248282 No abstract available.573Cite 

The oxidation of ferrocytochrome c by Br2-, (SCN)2-, N3 and OH radicals studied by pulsed-electron and gamma-ray radiolysis.

Seki H, Imamura M.Biochim Biophys Acta. 1981 Mar 12;635(1):81-9. doi: 10.1016/0005-2728(81)90009-8.PMID: 6260165574Cite 

The characterization and magnetic properties of the azide and imidazole derivatives of Pseudomonas nitrite reductase.

Walsh TA, Johnson MK, Thomson AJ, Barber D, Greenwood C.J Inorg Biochem. 1981 Feb;14(1):1-14. doi: 10.1016/s0162-0134(00)80010-0.PMID: 6260896

Attempts to obtain a high-spin heme d1 in the intact enzyme using the weak field ligands fluoride and thiocyanate have proved unsuccessful. Electron paramagnetic resonance experiments involving an oxidized enzyme derivatives in which heme d1 is complexed by NO, and hence e …575Cite 

[Use of a modified Aldridge method for the elimination of certain amino acids and protein components interfering with the determination of thiocyanate in human and animal sera (author’s transl)].

Thürkow B, Weuffen W.Pharmazie. 1980 Aug;35(8):475-8.PMID: 7433496 German.

Since the amino acids and protein components remaining in the supernatant after protein precipitation react with bromine to give cyanogen bromide just as thiocyanate, they interfere with the determination of human and animal sera by the Aldridge method. This interference i …576Cite 

Regulatory effects of iodide and thiocyanate on tyrosine oxidation catalyzed by thyroid peroxidase.

Michot JL, Osty J, Nunez J.Eur J Biochem. 1980 Jun;107(2):297-301. doi: 10.1111/j.1432-1033.1980.tb06029.x.PMID: 7398641 Free article.

the effects of iodide, thiocyanate and perchlorate, three anions with the same molecular size, on the oxidation of tyrosine to 3,3′-bityrosine by several peroxidases were evaluated at pH 8.8, i.e. in conditions in which iodide is not oxidized. …SCN- mimics iodide effects …577Cite 

Mechanisms of inactivation of molybdoenzymes by cyanide.

Coughlan MP, Johnson JL, Rajagopalan KV.J Biol Chem. 1980 Apr 10;255(7):2694-9.PMID: 6244290 Free article.

Following gel filtration to remove excess of reductant and cyanide, the isolated enzymes remain inactive. Thiocyanate, a product of inactivation of the oxidized forms of the xanthine- and aldehyde-oxidizing enzymes by cyanide, is not released during inactivation of the red …578Cite 

Synthesis, redox characteristics, and in vitro norepinephrine uptake inhibiting properties of 2-(2-mercapto-4,5-dihydroxyphenyl)ethylamine (6-mercaptodopamine).

Chavdarian CG, Castagnoli N Jr.J Med Chem. 1979 Nov;22(11):1317-22. doi: 10.1021/jm00197a008.PMID: 533879

The synthesis of 6-mercaptodopamine was achieved by the regioselective thiocyanation of O,O-dimethyldopamine, followed by bis-O-demethylation and reductive cleavage of the S-cyano group. …579Cite 

Antibacterial action of lactoperoxidase-thiocyanate-hydrogen peroxide on Streptococcus agalactiae.

Mickelson MN.Appl Environ Microbiol. 1979 Nov;38(5):821-6. doi: 10.1128/aem.38.5.821-826.1979.PMID: 396883 Free PMC article.

Antibacterial activity of lactoperoxidase (LP)-thiocyanate (SCN)-hydrogen peroxide (H2O2) on Streptococcus agalactiae requires that the three reactants must be in contact with the cells simultaneously. …580Cite 

Free radical reactions with proteins and enzymes: the inactivation of pepsin.

Adams GE, Posener ML, Bisby RH, Cundall RB, Key JR.Int J Radiat Biol Relat Stud Phys Chem Med. 1979 Jun;35(6):497-507. doi: 10.1080/09553007914550611.PMID: 383634

The reactions of the more selective oxidizing inorganic radical anions Br2-. and (SCN)2-., with pepsin have also beenexamined. In the case of the thiocyanate radical anion (SCN)2-., the inactivation efficiency is found to depend on SCN- concentration, an effect shown to ar …581Cite 

The membrane potential in everted vesicles of Escherichia coli.

Singh AP, Bragg PD.Arch Biochem Biophys. 1979 Jun;195(1):74-80. doi: 10.1016/0003-9861(79)90328-x.PMID: 38747 No abstract available.582Cite 

Formation of dityrosine by human salivary lactoperoxidase in vitro.

Tenovuo J, Paunio K.Acta Odontol Scand. 1979;37(3):147-52. doi: 10.3109/00016357909004689.PMID: 39419

Dityrosine formation was found at pH range 6.6 to 9.3 with maximum reaction velocity at pH 8.5. However, thiocyanate ions at physiological salivary concentrations inhibited dityrosine formation by 70 to 80 per cent compared with the optimum rate. …583Cite 

Characteristics of Thiobacillus thioparus and its thiocyanate assimilation.

Katayama Y, Kuraishi H.Can J Microbiol. 1978 Jul;24(7):804-10. doi: 10.1139/m78-135.PMID: 28174

Thiocyanate-assimilatig bacterium, TK 21, was isolated from activated sludge used for the treatment of thiocyanate contained in coke-oven liquor. …These facts indicated that it belongs to the genus Thiobacillus. Potassium thiocyanate (0.5 g/l) was completel …584Cite 

Lactoperoxidase, peroxide, thiocyanate antimicrobial system: correlation of sulfhydryl oxidation with antimicrobial action.

Thomas EL, Aune TM.Infect Immun. 1978 May;20(2):456-63. doi: 10.1128/iai.20.2.456-463.1978.PMID: 352945 Free PMC article.

The antimicrobial activity of the lactoperoxidase, peroxide, thiocyanate system against Escherichia coli was directly related to the oxidation of bacterial sulfhydryls. Lactoperoxidase catalyzed the oxidation of thiocyanate, which resulted in the accumulation of hyp …585Cite 

Chloride and sulfate transport in Ehrlich ascites tumor cells: evidence for a common mechanism.

Levinson C.J Cell Physiol. 1978 Apr;95(1):23-32. doi: 10.1002/jcp.1040950104.PMID: 565363586Cite 

The electrochemical proton gradient generated by light in membrane vesicles and chromatophores from Rhodopseudomonas sphaeroides.

Michels PA, Konings WN.Eur J Biochem. 1978 Apr;85(1):147-55. doi: 10.1111/j.1432-1033.1978.tb12222.x.PMID: 25184 Free article. No abstract available.587Cite 

Oxidation of protein sulfhydryls by products of peroxidase-catalyzed oxidation of thiocyanate ion.

Aune TM, Thomas EL.Biochemistry. 1978 Mar 21;17(6):1005-10. doi: 10.1021/bi00599a010.PMID: 204336 No abstract available.588Cite 

Continuous monitoring of the electrical potential across energy-transducing membranes using ion-selective electrodes. Application to submitochondrial particles and chromatophores.

Kell DB, John P, Sorgato MC, Ferguson SJ.FEBS Lett. 1978 Feb 15;86(2):294-8. doi: 10.1016/0014-5793(78)80583-3.PMID: 414935 Free article. No abstract available.589Cite 

A study on nitrate reductase from Propionibacterium acidi-propionici.

Kaneko M, Ishimoto M.J Biochem. 1978 Jan;83(1):191-200. doi: 10.1093/oxfordjournals.jbchem.a131891.PMID: 624703 Free article.

Chlorate was an active acceptor as well as nitrate. Azide, cyanide, and thiocyanate inhibited NaR. On adding 1 mM tungstate to the growing medium, the NaR level in grown cells was lowered; addition of 0.01 mM molybdate restored the activity partially. …590Cite 

Substitution reactions of a water-soluble metalloporphyrin with azide and 1,1,3,3-tetramethyl-2-thiourea.

Pasternack RF, Gillies BS, Stromsted JP.Bioinorg Chem. 1978;8(1):33-44. doi: 10.1016/s0006-3061(00)80003-4.PMID: 623832

The mechanistic pathway proposed for thiocyanate [1] and pyridine [2] is applicable to these ligands as well once allowance is made for two attacking forms of azide, N3- and HN3. …591Cite 

Inhibition by thiocyanate of lactoperoxidase-catalysed oxidation and iodination reactions.

Tenovuo J.Arch Oral Biol. 1978;23(10):899-903. doi: 10.1016/0003-9969(78)90294-7.PMID: 33640 No abstract available.592Cite 

Accumulation of hypothiocyanite ion during peroxidase-catalyzed oxidation of thiocyanate ion.

Aune TM, Thomas EL.Eur J Biochem. 1977 Oct 17;80(1):209-14. doi: 10.1111/j.1432-1033.1977.tb11873.x.PMID: 562752 Free article. No abstract available.593Cite 

Use of diethazine hydrochloride for the extractive spectrophotometric determination of uranium and as a redox indicator.

Puzanowska-Tarasiewicz H, Tarasiewicz M, Grudniewska A.Talanta. 1977 Oct;24(10):609-12. doi: 10.1016/0039-9140(77)80104-5.PMID: 18962157

Optimum conditions have been established for the formation and extraction of the complex formed from diethazine, thiocyanate and uranium(VI). An extractive spectrophotometric method for the determination of uranium(VI) is described. Experimental conditions have been also e …594Cite 

Factors in the analysis of whole blood thiocyanate.

Ballantyne B.Clin Toxicol. 1977 Sep;11(2):195-210. doi: 10.3109/15563657708989833.PMID: 891112 No abstract available.595Cite 

A protonmotive force as the source of energy for galactoside transport in energy depleted Escherichia coli.

Flagg JL, Wilson TH.J Membr Biol. 1977 Mar 8;31(3):233-55. doi: 10.1007/BF01869407.PMID: 15125

The membrane potential (inside negative) was established by the outward diffusion of potassium (in the presence of valinomycin) or by the inward diffusion of the permeant thiocyanate ion. The magnitude of the electrochemical potential difference for protons agreed well wit …596Cite 

[Thiocyanatochromium (III) complexes in chemical analysis. 26. Oxidimetric and spectrophotometric determination of chlordiazepoxide and tetrathiocyanato-diamine-chromiates].

Ganescu I, Várhelyi C, Brinzan G, Boboc L.Pharmazie. 1977 Jan;32(1):53.PMID: 840887 German. No abstract available.597Cite 

Hypothiocyanite ion; the inhibitor formed by the system lactoperoxidase-thiocyanate-hydrogen peroxide. I. Identification of the inhibiting compound.

Hoogendoorn H, Piessens JP, Scholtes W, Stoddard LA.Caries Res. 1977;11(2):77-84. doi: 10.1159/000260252.PMID: 265188 No abstract available.598Cite 

Photophosphorylation as a function of illumination time. I. Effects of permeant cations and permeant anions.

Ort DR, Dilley RA.Biochim Biophys Acta. 1976 Oct 13;449(1):95-107. doi: 10.1016/0005-2728(76)90010-4.PMID: 61766

Potassium ions in the presence of valinomycin increase the delay to a maximum of about 50 ms whereas thiocyanate ions increase the delay to a maximum of about 25 ms. The effects of K+ with valinomycin and the effect of SCN- are not additive. …599Cite 

Titrimetric determination of thiocyanate and thiosulphate ions by oxidation with iodine in alkaline solution.

Belcher R, Liao SS, Townshend A.Talanta. 1976 Jul;23(7):541-3. doi: 10.1016/0039-9140(76)80152-x.PMID: 18961918

Thiocyanate (2.7-90 mug) and thiosulphate (4.5-90 mug) ions are oxidized by iodine in alkaline media to sulphate ions. …Each thiocyanate and thiosulphate ion results in the ultimate production of 19 and 24 iodine molecules, respectively….600Cite 

[Thiocynanatochromium(III) complexes in chemical analysis. 25. Oxydometric and spectrophotometric determination of diazepam with Reinecke salt-like compounds].

Gånescu I, Várhelyi C, Grínzan G, Boboc L.Pharmazie. 1976 Apr;31(4):259.PMID: 935234 German. No abstract available.

601Cite 

Conformational changes in cytochrome aa3 and ATP synthetase of the mitochondrial membrane and their role in mitochondrial energy transduction.

Wikström MK, Saari HT.Mol Cell Biochem. 1976 Mar 26;11(1):17-33. doi: 10.1007/BF01792831.PMID: 5667 Review.

This control is exerted by a regulatory mechanism in which the electrical potential difference controls the conformation and redox properties of the heme centres and thereby the rate of oxygen consumption. 5. The synthesis of one molecule of ATP by oxidative phosphorylatio …602Cite 

Quantitative determination of methionine in proteins: gas chromatography of methylthiocyanate liberated by cleavage with cyanogen bromide.

Váradi A, Pongor S, Kaul AK.Acta Biochim Biophys Acad Sci Hung. 1976;11(2-3):87-93.PMID: 1007888603Cite 

Turku sugar studies XII. The effect of the diet on oral peroxidases, redox potential and the concentration of ionized fluorine, iodine and thiocyanate.

Mäkinen KK, Tenovuo J, Scheinin A.Acta Odontol Scand. 1976;34(6):353-69. doi: 10.3109/00016357609004647.PMID: 797223

There were no significant differences between the sugar groups in the concentration of thiocyanate ions (mean 92 mg/l) and ionized iodine (mean 1.6 mug/l), but the concentration of ionized fluorine in saliva was lower in the xylitol group (0.128 mg/l) than in the other gro …604Cite 

[Degradation of sulfur compounds by pure cultures of Thiobacillus].

Feldmann K, Goroll D.Z Allg Mikrobiol. 1976;16(4):255-8. doi: 10.1002/jobm.3630160403.PMID: 785827 German. No abstract available.605Cite 

Fluorescein conjugates of cytochrome c as internal pH probes in submitochondrial particles.

Thomas JA, Johnson DL.Biochem Biophys Res Commun. 1975 Aug 4;65(3):931-9. doi: 10.1016/s0006-291x(75)80475-x.PMID: 239716 No abstract available.606Cite 

Evidence for the formation of a protein bound hydrodisulfide resulting from the microsomal mixed function oxidase catalyzed desulfuration of carbon disulfide.

Catignani GL, Neal RA.Biochem Biophys Res Commun. 1975 Jul 22;65(2):629-36. doi: 10.1016/s0006-291x(75)80193-8.PMID: 238535 No abstract available.607Cite 

Amino acid sequence of Streptomyces griseus trypsin. Cyanogen bromide fragments and complete sequence.

Olafson RW, Jurásek L, Carpenter MR, Smillie LB.Biochemistry. 1975 Mar 25;14(6):1168-77. doi: 10.1021/bi00677a011.PMID: 804314608Cite 

The kinetics of oxidation of reduced cytochrome c by ferricyanide derivatives.

Cassatt JC, Marini CP.Biochemistry. 1974 Dec 17;13(26):5323-8. doi: 10.1021/bi00723a011.PMID: 4373036 No abstract available.609Cite 

Acid-base titration of hemocyanin from Octopus vulgaris Lam.

Salvato B, Ghiretti-Magaldi A, Ghiretti F.Biochemistry. 1974 Nov 5;13(23):4778-83. doi: 10.1021/bi00720a015.PMID: 4429662 No abstract available.610Cite 

Interactions between oxidative metabolism and acid secretion in gastric mucosa.

Hersey SJ.Biochim Biophys Acta. 1974 Sep 16;344(2):157-203. doi: 10.1016/0304-4157(74)90003-3.PMID: 4153976 Review. No abstract available.611Cite 

Mid-potential measurements of unidentified component, controlling the rate of reduction of the b-type cytochromes.

Eisenbach M, Gutman M.FEBS Lett. 1974 Sep 15;46(1):368-71. doi: 10.1016/0014-5793(74)80409-6.PMID: 4423455 Free article. No abstract available.612Cite 

Letter: Mechanism of reduction of 1-methyl-4-thiocyanatouracil by bisulfide. A route to in vitro labeling of tRNAs with sulfur-35.

Pal BC, Schmidt DG.J Am Chem Soc. 1974 Sep 4;96(18):5943-4. doi: 10.1021/ja00825a046.PMID: 4606738 No abstract available.613Cite 

Biochemical studies on accelerated treatment of thiocyanate by activated sludge using growth factors such as pyruvate.

Woodard AJ, Stafford DA, Callely AG.J Appl Bacteriol. 1974 Sep;37(3):277-87. doi: 10.1111/j.1365-2672.1974.tb00442.x.PMID: 4420779 No abstract available.614Cite 

Amino acid sequence of ferredoxin from a photosynthetic green bacterium, Chlorobium limicola.

Tanaka M, Haniu M, Yasunobu KT, Evans MC, Rao KK.Biochemistry. 1974 Jul 2;13(14):2953-9. doi: 10.1021/bi00711a026.PMID: 4407619 No abstract available.615Cite 

Delayed light studies on photosynthetic energy conversion. VII. Effect of the high energy state, coupled to 2,3,5,6-tetramethyl p-phenylenediamine-catalyzed cyclic electron flow, on millisecond emission from chloroplasts and digitonin subchloroplast particles.

Cohen WS, Bertsch W.Biochim Biophys Acta. 1974 Jun 28;347(3):371-82. doi: 10.1016/0005-2728(74)90076-0.PMID: 4135380 No abstract available.616Cite 

Observations on the effects of chromate on the thyroid.

Chiraseveenuprapund P, Rosenberg IN.Endocrinology. 1974 Jun;94(6):1714-22. doi: 10.1210/endo-94-6-1714.PMID: 4364641 No abstract available.617Cite 

Perturbation of leukocyte metabolism by nonphagocytosable concanavalin A-coupled beads.

Romeo D, Jug M, Zabucchi G, Rossi F.FEBS Lett. 1974 May 15;42(1):90-3. doi: 10.1016/0014-5793(74)80286-3.PMID: 4604894 Free article. No abstract available.618Cite 

[Thiocyanatochrome (3)-complexes in the chemical analysis. 22. Permanganometric and colorimetric determination of levopromazine using rhodanylate-like compounds].

Várhelyi C, Ganescu I, Boboc L.Pharmazie. 1974 May;29(5):348-9.PMID: 4849995 German. No abstract available.619Cite 

The mechanisms of hemoglobin autoxidation. Evidence for proton-assisted nucleophilic displacement of superoxide by anions.

Wallace WJ, Maxwell JC, Caughey WS.Biochem Biophys Res Commun. 1974 Apr 23;57(4):1104-10. doi: 10.1016/0006-291x(74)90810-9.PMID: 4830750 No abstract available.620Cite 

Synthesis, chemistry, and biological activity of 5-thiocyanatopyrimidine nucleosides as potential masked thiols.

Nagamachi T, Fourrey JL, Torrence PF, Waters JA, Witkop B.J Med Chem. 1974 Apr;17(4):403-6. doi: 10.1021/jm00250a006.PMID: 4524606 No abstract available.621Cite 

Role of phosphate and other proton-donating anions in respiration-coupled transport of Ca2+ by mitochondria.

Lehninger AL.Proc Natl Acad Sci U S A. 1974 Apr;71(4):1520-4. doi: 10.1073/pnas.71.4.1520.PMID: 4364542 Free PMC article.

Phosphate, arsenate, acetate, butyrate, beta-hydroxybutyrate, lactate, and bicarbonate + CO(2) supported Ca(2+) uptake, whereas the permeant anions, nitrate, thiocyanate, chlorate, and perchlorate, did not. The active anions share a common denominator, the potential abilit …622Cite 

Amino acid sequence of the (lambda) light chain of a human myeloma immunoglobulin (IgG New).

Chen BL, Poljak RJ.Biochemistry. 1974 Mar 12;13(6):1295-302. doi: 10.1021/bi00703a037.PMID: 4814727 No abstract available.623Cite 

[Preparation of coupling 6-mercaptopurine derivatives with isothiocyanate structure. 1. Immunosuppressive antigen conjugates].

Wagner G, Oehlke J, Pischel H.Pharmazie. 1974 Mar;29(3):160-4.PMID: 4849457 German. No abstract available.624Cite 

[Intoxication by products used in photography (baths, fixatives, developers)].

Larcan A, Lambert H, Laprevote-Heully MC, Bertrand D.Eur J Toxicol Environ Hyg. 1974 Jan;7(1):17-21.PMID: 4844307 French. No abstract available.625Cite 

Cyanylation of sulfhydryl groups by 2-nitro-5-thiocyanobenzoic acid. High-yield modification and cleavage of peptides at cysteine residues.

Degani Y, Patchornik A.Biochemistry. 1974 Jan 1;13(1):1-11. doi: 10.1021/bi00698a001.PMID: 4808702 No abstract available.626Cite 

Alignment and partial structural analysis of the cyanogen bromide fragments from yeast inorganic pyrophosphatase.

Sterner R, Noyes C, Heinrikson RL.Biochemistry. 1974 Jan 1;13(1):91-9. doi: 10.1021/bi00698a015.PMID: 4586936 No abstract available.627Cite 

Metabolism of propranolol in rat: the fate of the N-isopropyl group.

Bakke OM, Davies DS, Davies L, Dollery CT.Life Sci. 1973 Dec 16;13(12):1665-75. doi: 10.1016/0024-3205(73)90114-8.PMID: 4591189 No abstract available.628Cite 

Isolation and characterization of the glycopeptides of porcine pancreatic lipases L-A and L-B.

Plummer TH Jr, Sarda L.J Biol Chem. 1973 Nov 25;248(22):7865-9.PMID: 4796072 Free article. No abstract available.629Cite 

The amino acid sequence of ovine pancreatic ribonuclease A.

Kobayashi R, Hirs CH.J Biol Chem. 1973 Nov 25;248(22):7833-7.PMID: 4356260 Free article. No abstract available.630Cite 

Partial sequence of trypsin inhibitior from ovumucoid.

Murthy GS, Gilardeau C, Chrétien M.Can J Biochem. 1973 Nov;51(11):1548-51. doi: 10.1139/o73-207.PMID: 4797327 No abstract available.631Cite 

[The determination of a thiocyanate group in organic thiocyanate compounds and sulfuric acid thiocyanates. Report 47. Organic thiocyanates].

Kottke K, Friedrich F, Pohloudek-Fabini R.Pharmazie. 1973 Nov-Dec;28(11):736-7.PMID: 4791257 German. No abstract available.632Cite 

Sickle cell anemia and dietary precursors of cyanate.

Houston RG.Am J Clin Nutr. 1973 Nov;26(11):1261-4. doi: 10.1093/ajcn/26.11.1261.PMID: 4594066 Review. No abstract available.633Cite 

The b cytochromes in succinate–cytochrome c reductase from pigeon breast mitochondria.

Erecińska M, Oshino R, Oshino N, Chance B.Arch Biochem Biophys. 1973 Aug;157(2):431-45. doi: 10.1016/0003-9861(73)90659-0.PMID: 4354319 No abstract available.634Cite 

[Synthesis of 2,6-dimercapto-3-aryl-4-quinazolones and various derivatives].

Stájer G, Kottke K, Pohloudek-Fabini R.Pharmazie. 1973 Jul;28(7):433-7.PMID: 4767487 German. No abstract available.635Cite 

Amino acid sequence of the first 65 residues of IgA myeloma protein.

Shinoda T.Biochem Biophys Res Commun. 1973 Jun 19;52(4):1246-51. doi: 10.1016/0006-291x(73)90634-7.PMID: 4717746 No abstract available.636Cite 

On the NH 2 -terminal residue of hirudin.

Gráf L, Patthy A, Barabás EB, Bagdy D.Biochim Biophys Acta. 1973 Jun 15;310(2):416-7. doi: 10.1016/0005-2795(73)90123-2.PMID: 4719151 No abstract available.637Cite 

The pyridoxal phosphate-binding site of rabbit muscle aldolase.

Anai M, Lai CY, Horecker BL.Arch Biochem Biophys. 1973 Jun;156(2):712-9. doi: 10.1016/0003-9861(73)90324-x.PMID: 4736987 No abstract available.638Cite 

Cyanide-insensitive respiration. I. The steady states of skunk cabbage spadix and bean hypocotyl mitochondria.

Bahr JT, Bonner WD Jr.J Biol Chem. 1973 May 25;248(10):3441-5.PMID: 4349864 Free article. No abstract available.639Cite 

Anion-binding and the state of copper in caeruloplasmin.

Byers W, Curzon G, Garbett K, Speyer BE, Young SN, Williams RJ.Biochim Biophys Acta. 1973 May 17;310(1):38-50. doi: 10.1016/0005-2795(73)90006-8.PMID: 4351064 No abstract available.640Cite 

Structure of the flavin site of Chromatium flavocytochrome c -552.

Kenney WC, Edmondson D, Seng R, Singer TP.Biochem Biophys Res Commun. 1973 May 15;52(2):434-9. doi: 10.1016/0006-291x(73)90730-4.PMID: 4351136 No abstract available.641Cite 

Effect of metabolic inhibitors on the gastric mucosal barrier.

Ritchie WP Jr, Fischer RP.Surgery. 1973 Apr;73(4):614-22.PMID: 4690107 No abstract available.642Cite 

Structure of immunoglobulin A. Amino acid sequence of cysteine-containing peptides from the J chain.

Mendez E, Frangione B, Franklin EC.Biochemistry. 1973 Mar 13;12(6):1119-24. doi: 10.1021/bi00730a016.PMID: 4631861 No abstract available.643Cite 

Bovine pancreatic deoxyribonuclease A. Isolation, composition, and amino acid sequences of the tryptic and chymotryptic peptides.

Salnikow J, Liao TH, Moore S, Stein WH.J Biol Chem. 1973 Feb 25;248(4):1480-8.PMID: 4734470 Free article. No abstract available.644Cite 

Amino acid sequences at constant and variable regions of heavy chains of monotypic immunoglubulins G and M of a single patient.

Wang AC, Gergely J, Fudenberg HH.Biochemistry. 1973 Jan 30;12(3):528-34. doi: 10.1021/bi00727a027.PMID: 4683496 No abstract available.645Cite 

Biological oxidation and conjugation of pesticidal chemicals.

Menzer RE.Residue Rev. 1973;48(0):79-116. doi: 10.1007/978-1-4615-8498-8_3.PMID: 4604159 Review. No abstract available.646Cite 

Studies on the structure of T4 thioredoxin. II. Amino acid sequence of the protein and comparison with thioredoxin from Escherichia coli.

Sjöberg BM, Holmgren A.J Biol Chem. 1972 Dec 25;247(24):8063-8.PMID: 4565673 Free article. No abstract available.647Cite 

Studies on the structure of T4 thioredoxin. I. Isolation and amino acid sequence of the peptides obtained from a tryptic digest of the protein.

Sjöberg BM.J Biol Chem. 1972 Dec 25;247(24):8058-62.PMID: 4565672 Free article. No abstract available.648Cite 

Primary structure of Escherichia coli glutamine synthetase. 3. Chemical evidence for subunit identity; amino acid sequences at the NH 2 and COOH termini.

Kingdon HS, Noyes C, Lahiri A, Heinrikson RL.J Biol Chem. 1972 Dec 25;247(24):7923-6.PMID: 4404836 Free article. No abstract available.649Cite 

Specific cleavage between variable and constant domains of rabbit antibody light chains by dilute acid hydrolysis.

Fraser KJ, Pulsen K, Haber E.Biochemistry. 1972 Dec 19;11(26):4974-7. doi: 10.1021/bi00776a016.PMID: 4404720 No abstract available.650Cite 

Homology between bovine high molecular weight and low molecular weight kininogens.

Komiya M, Kata H, Suzuki T.Biochem Biophys Res Commun. 1972 Dec 18;49(6):1438-43. doi: 10.1016/0006-291x(72)90500-1.PMID: 4674282 No abstract available.651Cite 

Isolation and characterization of the tryptic and cyanogen bromide peptides of apoLp-Gln-II (apoA-II), plasma high density apolipoprotein.

Lux SE, John KM, Ronan R, Brewer HB Jr.J Biol Chem. 1972 Dec 10;247(23):7519-27.PMID: 4344225 Free article. No abstract available.652Cite 

The amino acid sequence of cytochrome c-553 from the Chrysophycean alga Monochrysis lutheri.

Laycock MV.Can J Biochem. 1972 Dec;50(12):1311-25. doi: 10.1139/o72-176.PMID: 4345913 No abstract available.653Cite 

A study of the cystine-containing apolipoprotein of human plasma high density lipoproteins: characterization of cyanogen bromide and tryptic fragments.

Jackson RL, Gotto AM.Biochim Biophys Acta. 1972 Nov 28;285(1):36-47. doi: 10.1016/0005-2795(72)90178-x.PMID: 4347238 No abstract available.654Cite 

Amino acid sequences of the two principal neurotoxins of Enhydrina schistosa venom.

Fryklund L, Eaker D, Karlsson E.Biochemistry. 1972 Nov 21;11(24):4633-40. doi: 10.1021/bi00774a034.PMID: 4676045 No abstract available.655Cite 

Location of sulfhydryl and disulfide groups in bovine -lactoglobulins and effects of urea.

McKenzie HA, Ralston GB, Shaw DC.Biochemistry. 1972 Nov 21;11(24):4539-47. doi: 10.1021/bi00774a017.PMID: 4569282 No abstract available.656Cite 

Isolation and characterization of electrophoretically homogeneous rabbit antihapten antibody populations. 3. NH 2 -terminal light chain sequence analyses of focused anti-p-azophenyltrimethylammonium and anti-p-azobenzenearsonate antibody fractions.

Freedman MH, Guyer RB, Terry WD.J Biol Chem. 1972 Nov 10;247(21):7051-61.PMID: 4117158 Free article. No abstract available.657Cite 

Ribonuclease of Chalaropsis species. II. Chemical properties.

Fletcher PL Jr, Hash JH.Biochemistry. 1972 Nov 7;11(23):4281-5. doi: 10.1021/bi00773a014.PMID: 5079899 No abstract available.658Cite 

Multiple hemoglobins of catostomid fish. II. The amino acid sequence of the major chain from Catostomus clarkii hemoglobins.

Powers DA, Edmundson AB.J Biol Chem. 1972 Oct 25;247(20):6694-707.PMID: 4672861 Free article. No abstract available.659Cite 

Structure of immunoglobulin A. II. Sequence around the hinge region and labile disulfide bonds of an immunoglobulin A2 myeloma protein.

Wolfenstein-Todel C, Frangione B, Franklin EC.Biochemistry. 1972 Oct 10;11(21):3971-5. doi: 10.1021/bi00771a021.PMID: 4562586 No abstract available.660Cite 

Isolation and partial characterization of the cyanogen bromide fragments of 1 -acid glycoprotein and the elucidation of the amino acid sequence of the carboxyl-terminal cyanogen bromide fragment.

Ikenaka T, Ishiguro M, Emura J, Kaufmann H, Isemura S, Bauer W, Schmid K.Biochemistry. 1972 Sep 26;11(20):3817-29. doi: 10.1021/bi00770a022.PMID: 4561179 No abstract available.661Cite 

An active derivative of rabbit antibody light chain composed of the constant and the variable domains held together only by a native disulfide bond.

Poulsen K, Fraser KJ, Haber E.Proc Natl Acad Sci U S A. 1972 Sep;69(9):2495-9. doi: 10.1073/pnas.69.9.2495.PMID: 4506770 Free PMC article.662Cite 

The chemical state of 99m Tc in biomedical products. II. The chelation of reduced technetium with DTPA.

Eckelman WC, Meinken G, Richards P.J Nucl Med. 1972 Aug;13(8):577-81.PMID: 5041632 Free article. No abstract available.663Cite 

Purification and characterization of two classes of immunoglobulins from the marine toad, Bufo marinus.

Acton RT, Evans EE, Weinheimer PF, Niedermeier W, Bennett JC.Biochemistry. 1972 Jul 18;11(15):2751-9. doi: 10.1021/bi00765a003.PMID: 4625312 No abstract available.664Cite 

Absence of a specific copper(II) binding site in dog albumin is due to amino acid mutation in position 3.

Dixon JW, Sarkar B.Biochem Biophys Res Commun. 1972 Jul 11;48(1):197-200. doi: 10.1016/0006-291x(72)90362-2.PMID: 5064954 No abstract available.665Cite 

The primary structure of ovine luteinizing hormone. I. The amino acid sequence of the reduced and S-aminoethylated S-subunit (LH- ).

Liu WK, Nahm HS, Sweeney CM, Lamkin WM, Baker HN, Ward DN.J Biol Chem. 1972 Jul 10;247(13):4351-64.PMID: 5064343 Free article. No abstract available.666Cite 

The primary structure of ovine luteinizing hormone. II. The amino acid sequence of the reduced, S-carboxymethylated A-subunit (LH- ).

Liu WK, Nahm HS, Sweeney CM, Holcomb GN, Ward DN.J Biol Chem. 1972 Jul 10;247(13):4365-81.PMID: 4556309 Free article. No abstract available.667Cite 

Isolation and characterization of discrete fragments of 27 S thyroid iodoprotein.

Bilstad JM, Edelhoch H, Lippoldt R, Rall JE, Salvatore G.Arch Biochem Biophys. 1972 Jul;151(1):341-50. doi: 10.1016/0003-9861(72)90505-x.PMID: 5044523 No abstract available.668Cite 

The sequence of SCMK-B2B, a high-sulfur protein from wool keratin.

Elleman TC, Dopheide TA.J Biol Chem. 1972 Jun 25;247(12):3900-9.PMID: 4555954 Free article. No abstract available.669Cite 

C-type cytochromes of Desulfovibrio vulgaris. The primary structure of cytochrome c 553.

Bruschi M, Le Gall J.Biochim Biophys Acta. 1972 Jun 22;271(1):48-60. doi: 10.1016/0005-2795(72)90131-6.PMID: 5038698 No abstract available.670Cite 

A method for obtaining large variable-region peptides from rabbit light chains.

Freedlender EF, Haber E.Biochemistry. 1972 Jun 6;11(12):2362-70. doi: 10.1021/bi00762a023.PMID: 4112871 No abstract available.671Cite 

Carbamyl- and methylthiocarbamylinsulins.

Lindsay DG, Loge O, Losert W, Shall S.Biochim Biophys Acta. 1972 May 18;263(3):658-65. doi: 10.1016/0005-2795(72)90047-5.PMID: 5034213 No abstract available.672Cite 

Large scale preparation of S-carboxymethylated chains of human fibrin and fibrinogen and the occurrence of -chain variants.

Henschen A, Edman P.Biochim Biophys Acta. 1972 Apr 15;263(2):351-67. doi: 10.1016/0005-2795(72)90088-8.PMID: 5031163 No abstract available.673Cite 

The isolation and primary structure of a paptide containing the oxidation–reduction active cystine of Escherichia coli lipoamide dehydrogenase.

Burleigh BD Jr, Williams CH Jr.J Biol Chem. 1972 Apr 10;247(7):2077-82.PMID: 4552686 Free article. No abstract available.674Cite 

The isolation and primary structure of a peptide containing the oxidation–reduction active cystine of Escherichia coli thioredoxin reductase.

Ronchi S, Williams CH Jr.J Biol Chem. 1972 Apr 10;247(7):2083-6.PMID: 4401439 Free article. No abstract available.675Cite 

The effect of 4-bromobenzyl isothiocyanate on the redox state of nicotinamide-adenine dinucleotides in Candida albicans.

Hasilík A, Livar M.Chem Biol Interact. 1972 Apr;4(5):305-10. doi: 10.1016/0009-2797(72)90084-1.PMID: 4400387 No abstract available.676Cite 

Amino acid sequence of the human haptoglobin beta chain. I. Amino- and carboxyl-terminal sequences.

Barnett DR, Lee TH, Bowman BH.Biochemistry. 1972 Mar 28;11(7):1189-94. doi: 10.1021/bi00757a012.PMID: 5062484 No abstract available.677Cite 

The influence of permeant anions upon mitochondrial energy conservation by means of a K + gradient.

Cockrell RS.Biochem Biophys Res Commun. 1972 Mar 24;46(6):1991-8. doi: 10.1016/0006-291x(72)90749-8.PMID: 5018663 No abstract available.678Cite 

The chemical structure of tryptophanase from Escherichia coli. 3. Isolation and amino acid sequence of the tryptic peptides.

Kagamiyama H, Matsubara H, Snell EE.J Biol Chem. 1972 Mar 10;247(5):1576-86.PMID: 4551944 Free article. No abstract available.679Cite 

The inhibition of ( 35 S)thiocyanate metabolism in the thyroid gland by thyroid-stimulating hormone.

Bobek S.J Endocrinol. 1972 Feb;52(2):219-27. doi: 10.1677/joe.0.0520219.PMID: 5015378 No abstract available.680Cite 

Molecular basis of insulin action: contributions of chemical modifications and synthetic approaches.

Zahn H, Brandenburg D, Gattner HG.Diabetes. 1972;21(2 Suppl):468-75. doi: 10.2337/diab.21.2.s468.PMID: 4559915 No abstract available.681Cite 

The reductive enzymatic cleavage of thiosulfate. Methods and appliction.

Hashwa F, Pfennig N.Arch Mikrobiol. 1972;81(1):36-44. doi: 10.1007/BF00715022.PMID: 4552952 No abstract available.682Cite 

Further studies on the structural differences between the isoenzymes of human parotid -amylase.

Keller PJ, Kauffman DL, Allan BJ, Williams BL.Biochemistry. 1971 Dec 21;10(26):4867-74. doi: 10.1021/bi00802a006.PMID: 5134534 No abstract available.683Cite 

Arginine decarboxylase from Escherichia coli. IV. Structure of the pyridoxal phosphate binding site.

Boeker EA, Fischer EH, Snell EE.J Biol Chem. 1971 Nov 25;246(22):6776-81.PMID: 4942324 Free article. No abstract available.684Cite 

Denaturation of globular proteins by guanidine thiocyanate. II. Intrinsic viscosities in 4.5 M quanidine thiocyanate solutions.

Lapanje S.Biochim Biophys Acta. 1971 Sep 28;243(3):357-65. doi: 10.1016/0005-2795(71)90002-x.PMID: 5166998 No abstract available.685Cite 

Denaturation of globular proteins by guanidine thiocyanate. I. Optical rotation in aqueous guanidine thiocyanate solutions.

Lapanje S.Biochim Biophys Acta. 1971 Sep 28;243(3):349-56. doi: 10.1016/0005-2795(71)90001-8.PMID: 5001983 No abstract available.686Cite 

The amino acid substitutions found in the genetic variants of 1 -acid glycoprotein.

Nimberg R, Motoyama T, Schmid K.J Biol Chem. 1971 Sep 25;246(18):5817-21.PMID: 4938040 Free article. No abstract available.687Cite 

Effect of anions on chloroplast particles.

McEvoy FA, Lynn WS.Biochem Biophys Res Commun. 1971 Sep 17;44(6):1388-93. doi: 10.1016/s0006-291x(71)80239-5.PMID: 5003691 No abstract available.688Cite 

Rotational relaxation time of pyridoxyl 5-phosphate lysozyme.

Irwin R, Churchich JE.J Biol Chem. 1971 Sep 10;246(17):5329-34.PMID: 5094672 Free article. No abstract available.689Cite 

The energetic coupling of acid secretion in gastric mucosa.

Hersey SJ.Philos Trans R Soc Lond B Biol Sci. 1971 Aug 20;262(842):261-75. doi: 10.1098/rstb.1971.0092.PMID: 4399218 No abstract available.690Cite 

Calorimetric studies of quaternary structure and ligand-binding hemerythrin.

Langerman N, Sturtevant JM.Biochemistry. 1971 Jul 20;10(15):2809-15. doi: 10.1021/bi00791a001.PMID: 4329807 No abstract available.691Cite 

Effects of chaotropic agents on the spectroscopic properties of spinach ferredoxin.

Cammack R, Rao KK, Hall DO.Biochem Biophys Res Commun. 1971 Jul 2;44(1):8-14. doi: 10.1016/s0006-291x(71)80151-1.PMID: 4330050 No abstract available.692Cite 

Succinate dehydrogenase. II. Enzymatic properties.

Hanstein WG, Davis KA, Ghalambor MA, Hatefi Y.Biochemistry. 1971 Jun 22;10(13):2517-24. doi: 10.1021/bi00789a015.PMID: 4326770 No abstract available.693Cite 

The primary structure of Chromatium high-potential iron-sulfur protein.

Dus K, Tedro S, Bartsch RG, Kamen MD.Biochem Biophys Res Commun. 1971 Jun 18;43(6):1239-45. doi: 10.1016/s0006-291x(71)80005-0.PMID: 5569110 No abstract available.694Cite 

Glycopeptides from silk fibroin of Bombyx mori.

Sinoara H, Asano Y, Fukui A.Biochim Biophys Acta. 1971 May 18;237(2):273-9. doi: 10.1016/0304-4165(71)90317-5.PMID: 4328392 No abstract available.695Cite 

Carboxy-terminal structure of the chain of human IgA myeloma proteins.

Prahl JW, Abel CA, Grey HM.Biochemistry. 1971 May 11;10(10):1808-12. doi: 10.1021/bi00786a012.PMID: 4998234 No abstract available.696Cite 

A comparison of some properties of microsomal cytochrome P-450 from normal, methylcholanthrene-, and phenobarbital-treated rats.

Imai Y, Siekevitz P.Arch Biochem Biophys. 1971 May;144(1):143-59. doi: 10.1016/0003-9861(71)90464-4.PMID: 5117524 No abstract available.697Cite 

[Bacteria oxidizing thiocyanates in industrial waste waters].

Iurovskaia EM.Mikrobiol Zh. 1971 Mar-Apr;33(2):148-52.PMID: 5092246 Ukrainian. No abstract available.698Cite 

Cyanide-insensitive Respiration in Plant Mitochondria.

Bendall DS, Bonner WD.Plant Physiol. 1971 Feb;47(2):236-45. doi: 10.1104/pp.47.2.236.PMID: 16657603 Free PMC article.

Skunk cabbage and mung bean mitochondria contain cytochromes a and a(3) that have absorption peaks differing slightly from those of animal preparations. A slow oxidation–reduction of cytochrome a(3)-CN has been demonstrated. Cytochromes b undergo oxidation and reduc …699Cite 

Isolation of a frog hemoglobin (Rana esculenta). Purification, amino acid composition, and terminal sequences of the and chains.

Chauvet JP, Acher R.Int J Protein Res. 1971;3(5):261-9.PMID: 4944748 No abstract available.700Cite 

On the mechanism of inactivation of xanthine oxidase by cyanide.

Massey V, Edmondson D.J Biol Chem. 1970 Dec 25;245(24):6595-8.PMID: 5536559 Free article. No abstract available.701Cite 

Oxidation of thiocyanate to cyanide and sulfate by the lactoperoxidase-hydrogen peroxide system.

Chung J, Wood JL.Arch Biochem Biophys. 1970 Nov;141(1):73-8. doi: 10.1016/0003-9861(70)90108-6.PMID: 5480127 No abstract available.702Cite 

The structure of the porcine pancreatic secretory trypsin inhibitor. I. A sequence determination by Edman degradation and mass spectral identification of the p-bromophenyl-thiohydantoins.

Tschesche H, Wachter E.Eur J Biochem. 1970 Sep;16(1):187-98. doi: 10.1111/j.1432-1033.1970.tb01071.x.PMID: 5466061 Free article. No abstract available.703Cite 

Studies of the electron transport chain of extremely halophilic bacteria. IV. Role of hydrophobic forces in the structure of menadione reductase.

Lanyi JK, Stevenson J.J Biol Chem. 1970 Aug 25;245(16):4074-80.PMID: 5496993 Free article. No abstract available.704Cite 

Tenative method of analysis for molybdenum content of atmospheric particulate matter. 12134-01-70T.

Tabor EC, Braverman MM, Bumstead HE, Carotti A, Donaldson HM, Dubois L, Kupel RE.Health Lab Sci. 1970 Jul;7(3):149-51.PMID: 5449672 No abstract available.705Cite 

Thiocyanato-indoles as energy-transfer inhibitors in photophosphorylation.

Brandon PC.Arch Biochem Biophys. 1970 Jun;138(2):655-73. doi: 10.1016/0003-9861(70)90382-6.PMID: 4393556 No abstract available.706Cite 

The oxidation of reduced nicotinamide nucleotides by hydrogen peroside in the presence of lactoperoxidase and thiocyanate, iodide or bromide.

Hogg DM, Jago GR.Biochem J. 1970 May;117(4):791-7. doi: 10.1042/bj1170791.PMID: 4317722 Free PMC article.

Lactoperoxidase (EC 1.11.1.7) catalysed the oxidation of NADH by hydrogen peroxide in the presence of either thiocyanate, iodide or bromide. In the presence of thiocyanate, net oxidation of thiocyanate occurred simultaneously with the oxidation of NADH, but i …707Cite 

Lipid oxidation in biological membranes. II. Kinetics and mechanism of lipid oxidation in submitochondrial particles.

Hanstein WG, Hatefi Y.Arch Biochem Biophys. 1970 May;138(1):87-95. doi: 10.1016/0003-9861(70)90287-0.PMID: 4315698 No abstract available.708Cite 

Lipid oxidation in biological membranes. I. Lipid oxidation in submitochondrial particles and microsomes induced by chaotropic agents.

Hatefi Y, Hanstein WG.Arch Biochem Biophys. 1970 May;138(1):73-86. doi: 10.1016/0003-9861(70)90286-9.PMID: 4315697 No abstract available.709Cite 

The effects of carbon dioxide and bicarbonate on chloride fluxes across frog gastric mucosa.

Imamura A.Biochim Biophys Acta. 1970;196(2):245-53. doi: 10.1016/0005-2736(70)90012-x.PMID: 5414305 No abstract available.710Cite 

Studies on the structure of the mitochondrial membranes.

Lenaz G.Ital J Biochem. 1970 Jan-Feb;19(1):54-82.PMID: 4245917 No abstract available.711Cite 

Sequential degradation of peptides with an insoluble Edman reagent.

Dowling LM, Stark GR.Biochemistry. 1969 Dec;8(12):4728-34. doi: 10.1021/bi00840a011.PMID: 5365780 No abstract available.712Cite 

Kinetics of the resolution of complex I (reduced diphosphopyridine nucleotide-coenzyme Q reductase) of the mitochondrial electron transport system by chaotropic agents.

Davis KA, Hatefi Y.Biochemistry. 1969 Aug;8(8):3355-61. doi: 10.1021/bi00836a033.PMID: 4390165 No abstract available.713Cite 

Redox changes in the respiratory chain related to acid secretion by the intact gastric mucosa.

Hersey SJ, Jöbsis FF.Biochem Biophys Res Commun. 1969 Jul 23;36(2):243-50. doi: 10.1016/0006-291x(69)90321-0.PMID: 5799643 No abstract available.714Cite 

[On the determination of oxidising substances in biological matter using iron-II-ammonium sulfate/ammonium rhodanide].

Wagner H, Schulz M, Pradel I.Radiobiol Radiother (Berl). 1969;10(2):201-8.PMID: 5794360 German. No abstract available.715Cite 

[Some molecular and complex-chemical properties of mesomethemoglobin].

Behlke J, Scheler W.Acta Biol Med Ger. 1969;23(6):733-45.PMID: 5375476 German. No abstract available.716Cite 

Association of thiocynate with reduced bovine albumin: essential features of the binding sites.

Pande CS, McMenamy RH.Biopolymers. 1968 Oct;6(10):1487-90. doi: 10.1002/bip.1968.360061011.PMID: 5685105 No abstract available.717Cite 

Sequential degradation of peptides from their carboxyl termini with ammonium thiocyanate and acetic anhydride.

Stark GR.Biochemistry. 1968 May;7(5):1796-807. doi: 10.1021/bi00845a026.PMID: 5689841 No abstract available.718Cite 

Relationships between the copper atoms of caeruloplasmin. 3. A difference in the reactivity of the chromophoric sites.

Marriott J, Perkins DJ.Biochim Biophys Acta. 1968 Apr 9;154(3):501-6. doi: 10.1016/0005-2795(68)90010-x.PMID: 5650417 No abstract available.719Cite 

Cytostatic activity and metabolic effects of aromatic isothiocyanic acid esters.

Daehnfeldt JL.Biochem Pharmacol. 1968 Apr;17(4):511-8. doi: 10.1016/0006-2952(68)90266-9.PMID: 5689772 No abstract available.720Cite 

Super-stoichiometric ratios between ion movements and electron transport in rat liver mitochondria.

Carafoli E, Gamble RL, Rossi CS, Lehninger AL.J Biol Chem. 1967 Mar 25;242(6):1199-204.PMID: 6024755 Free article. No abstract available.721Cite 

Partial characterization of protocollagen from embryonic cartilage.

Kivirikko KI, Prockop DJ.Biochem J. 1967 Feb;102(2):432-42. doi: 10.1042/bj1020432.PMID: 6029602 Free PMC article.

Significant purification of the protocollagen polypeptides was obtained with a new technique for DEAE-Sephadex chromatography in which urea was used to prevent aggregation of the samples and the column was eluted with guanidine thiocyanate. 5. Protocollagen polypeptides we …722Cite 

Interactions between cytochrome system and H ion secretion in bullfrog gastric mucosa.

Kidder GW 3rd, Curran PF, Rehm WS.Am J Physiol. 1966 Aug;211(2):513-9. doi: 10.1152/ajplegacy.1966.211.2.513.PMID: 4288381 No abstract available.723Cite 

[Competitive inhibitors of nitrate reduction by xanthine oxidase].

Hackenthal E, Hackenthal R.Naturwissenschaften. 1966 Feb;53(3):81. doi: 10.1007/BF00594755.PMID: 4293554 German. No abstract available.724Cite 

STUDIES ON AN IODINATING ENZYME FROM CALF THYROID.

DEGROOT LJ, THOMPSON JE, DUNN AD.Endocrinology. 1965 Apr;76:632-45. doi: 10.1210/endo-76-4-632.PMID: 14289184 No abstract available.725Cite 

[THE REDUCTION OF THIOCYANATED SCHIFF BASES WITH NASCENT HYDROGEN. 8. ON ORGANIC THIOCYANATE COMPOUNDS].

SCHULZ D, POHLOUDEK-FABINI R.Arch Pharm Ber Dtsch Pharm Ges. 1964 Dec;297:757-65. doi: 10.1002/ardp.19642971209.PMID: 14337682 German. No abstract available.726Cite 

[Hydrogenation experiments on thiocyanated Schiff bases with complex metal hydrides. 7. On organic thiocyanates].

Pohloudek-Fabini R, Schulz D.Arch Pharm Ber Dtsch Pharm Ges. 1964 Nov;297(11):649-60. doi: 10.1002/ardp.19642971103.PMID: 5212808 German. No abstract available.727Cite 

A DISSIMILATORY NITRATE REDUCTASE FROM NEUROSPORA CRASSA.

NICHOLAS DJ, WILSON PJ.Biochim Biophys Acta. 1964 Jun 8;86:466-76. doi: 10.1016/0304-4165(64)90086-8.PMID: 14192898 No abstract available.728Cite 

THE OXIDATION OF THIOCYANATE BY A CYTOPLASMIC PARTICULATE FRACTION OF THYROID TISSUE.

MALOOF F, SOODAK M.J Biol Chem. 1964 Jun;239:1995-2001.PMID: 14213389 Free article. No abstract available.729Cite 

ANION REQUIREMENTS FOR GASTRIC ACID SECRETION.

DURBIN RP.J Gen Physiol. 1964 Mar;47(4):735-48. doi: 10.1085/jgp.47.4.735.PMID: 14127609 Free PMC article.

A familiar inhibitor of gastric acid production, thiocyanate ion, appears to act by competition with chloride in a reaction leading to the formation of acid. This reaction is included in a hypothetical reaction cycle, generalized from the redox model for gastric aci …730Cite 

[Histochemical changes of some dehydrogenase activities of the rat thyroid after administration of thiocyanate and methylthiouracil].

MELANI F, GENTILINI P.Sperimentale. 1962 Nov-Dec;112:496-506.PMID: 13934636 Italian. No abstract available.731Cite 

Effect of some antithyroid substances on the histochemically demonstrable succinic dehydrogenase activity in the thyroid of guinea-pig.

KUUSISTO AN, TELKKA A.Ann Med Exp Biol Fenn. 1954;32(4):337-41.PMID: 14377035 No abstract available.732Cite 

Microbiological oxidation of ammonium and thiocyanate ions in soil.

GLEEN H.Nature. 1951 Jul 21;168(4264):117-8. doi: 10.1038/168117b0.PMID: 14852981 No abstract available.733Cite 

Inhibitory effect of thiocyanate upon oxidations mediated by liver and kidney.

OLSEN NS.Arch Biochem. 1950 Apr;26(2):269-74.PMID: 15411200 No abstract available.