Lactoperoxidase: Properties, Functions, and Potential Applications.
Özhan HK, Duman H, Bechelany M, Karav S.Int J Mol Sci. 2025 May 24;26(11):5055. doi: 10.3390/ijms26115055.PMID: 40507866 Free PMC article. Review.
It catalyzes the oxidation of certain molecules such as thiocyanate (SCN(-)), I(-), and Br(-) in the presence of hydrogen peroxide (H(2)O(2)). This reaction leads to the formation of antimicrobial products that have a great antimicrobial spectrum, including a …2Cite
Genome-wide characterization of hypothiocyanite stress response in Escherichia coli.
Meredith JD, Gray MJ.J Bacteriol. 2025 May 22;207(5):e0052424. doi: 10.1128/jb.00524-24. Epub 2025 Apr 29.PMID: 40298396 Free PMC article.3Cite
Electric field-induced control of protein crystal morphology.
Ray D, Madani M, Dhont JKG, Platten F, Kang K.Soft Matter. 2025 Apr 16;21(16):3012-3021. doi: 10.1039/d5sm00181a.PMID: 40152611
Lett., 2024, 15, 8108-8113), we found that an alternating electric field considerably affects the location of the crystallization boundary and the liquid-liquid phase separation line as well as crystallization kinetics in lysozyme solutions containing sodium thiocyanate (N …4Cite
Kaupke A, Kwit E, Bigoraj E, Radko L, Spiess K, Rzeżutka A.Res Vet Sci. 2025 May;187:105567. doi: 10.1016/j.rvsc.2025.105567. Epub 2025 Feb 10.PMID: 400073575Cite
Saha R, Bhattacharya I, Pyne S, Mitra RK.J Phys Chem B. 2025 Feb 20;129(7):1946-1955. doi: 10.1021/acs.jpcb.4c07470. Epub 2025 Feb 12.PMID: 39936570
Thiocyanate (SCN(-)) is known to be a naive ion abundant in biological fluids, blood, and urine. …6Cite
Eg Gadegaard IS, Eskildsen MH, Østergaard SK, Nielsen JL, Rasmussen JT.Food Res Int. 2025 Feb;201:115596. doi: 10.1016/j.foodres.2024.115596. Epub 2024 Dec 30.PMID: 39849752 Free article.
Xanthine oxidase (XO) and lactoperoxidase (LPO) are highly abundant enzymes in milk. Their substrates, xanthine and thiocyanate, are found in elevated amounts in infant saliva, leading to a proposed interaction between milk and saliva referred to as the XO-LPO system. …7Cite
Can a diet rich in Brassicaceae help control Helicobacter pylori infection? A systematic review.
Properzi S, Stracci F, Rosi M, Lupi C, Villarini A, Gili A.Front Med (Lausanne). 2024 Dec 17;11:1454902. doi: 10.3389/fmed.2024.1454902. eCollection 2024.PMID: 39741515 Free PMC article.
Emerging evidence suggests that Brassicaceae-derived metabolites could serve as adjunctive therapy for Hp infection, offering potential antimicrobial and anti-inflammatory benefits. METHODS: A systematic literature review was conducted following PRISMA guidelines to assess …8Cite
Abdelmonsef AH, El-Naggar M, Ibrahim AOA, Abdelgeliel AS, Shehadi IA, Mosallam AM, Khodairy A.Molecules. 2024 Nov 22;29(23):5529. doi: 10.3390/molecules29235529.PMID: 39683688 Free PMC article.
The starting compound 1 was prepared by reaction of 4-(2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-benzoyl chloride with ammonium thiocyanate and cyanoacetic acid hydrazide. The reaction of 1 with strong electrophiles, namely, o-aminophenol, o-amino thiophenol, and/or o-phen …9Cite
Total RNA Extraction from Rice Vegetative Tissues Using Magnetic Beads.
Yoshino K, Kawakatsu T.Methods Mol Biol. 2025;2869:7-13. doi: 10.1007/978-1-0716-4204-7_2.PMID: 39499462
In this chapter, we describe a high-throughput RNA extraction method using guanidine thiocyanate and isopropyl alcohol (HighGI). The use of carboxyl-coated paramagnetic beads, instead of silica membrane columns, enables semi-automation using a liquid handling system and hi …10Cite
Devi Karthikeyan P, Thomas R, Gunasekaran A, Tewari N, Upadhyay AD, Morankar R, Mathur VP, Bansal K.J Esthet Restor Dent. 2025 Feb;37(2):571-576. doi: 10.1111/jerd.13336. Epub 2024 Oct 15.PMID: 39404155
OBJECTIVE: Tooth bleaching procedures on nonvital teeth have been performed for crown discoloration caused by regenerative endodontic therapy (RET). However, leakage of bleaching agents across the root canal can be detrimental. This study aimed to assess and compare the pe …11Cite
In Vitro Effects of Zinc Compounds on the Candidacidal Activities of Salivary Antimicrobials.
Park YJ, Kim YY, Chang JY, Kho HS.Int Dent J. 2025 Apr;75(2):1261-1268. doi: 10.1016/j.identj.2024.09.006. Epub 2024 Oct 9.PMID: 39384441 Free PMC article.
METHODS: Four zinc compounds were used: zinc chloride, gluconate, lactate, and sulphate. Three antimicrobial systems were used: hen egg-white lysozyme (HEWL), the PO system [bovine lactoperoxidase (bLPO), potassium thiocyanate, and hydrogen peroxide], and the GO-PO …12Cite
P S, S GK, Kt N, Selvaraj C, K L.Scientifica (Cairo). 2024 Aug 16;2024:6645824. doi: 10.1155/2024/6645824. eCollection 2024.PMID: 39184813 Free PMC article.
The results of different assays, such as alpha-diphenyl-beta-picrylhydrazyl (DPPH), superoxide, nitric oxide scavenging assays, and total antioxidant by thiobarbituric acid method (TBA) and ferric thiocyanate (FTC) method, demonstrated a substantial scavenging of free radi …13Cite
Izzi G, Paladino A, Oliva R, Barra G, Ruggiero A, Del Vecchio P, Vitagliano L, Graziano G.Protein Sci. 2024 Sep;33(9):e5146. doi: 10.1002/pro.5146.PMID: 39150147 Free PMC article.
D2 is a structural and cooperative domain of Thermotoga maritima Arginine Binding Protein, that possesses a remarkable conformational stability, with a denaturation temperature of 102.6C, at pH 7.4. The addition of potassium thiocyanate causes a significant decrease in the …14Cite
Petithomme-Nanrocki M, Nicolau-Guillaumet N, Borie N, Haudrechy A, Renault JH, Moussalih S, Muggeo A, Guillard T.PLoS One. 2024 Aug 14;19(8):e0306259. doi: 10.1371/journal.pone.0306259. eCollection 2024.PMID: 39141636 Free PMC article.15Cite
Glucosinolate derivatives as antifungals: A review.
Patil S, Gavandi T, Karuppayil SM, Jadhav A.Phytother Res. 2024 Nov;38(11):5052-5066. doi: 10.1002/ptr.8307. Epub 2024 Aug 5.PMID: 39101575 Review.
The wide range of chemical structures, low cost, high availability, high antimicrobial action, and lack of adverse effects are the characteristics of plant secondary metabolites. …Antifungal activity of nitrile, epithionitrile, oxazolidine-2-thion, and thiocyanate …16Cite
Oblak A, Imperl J, Kolar M, Marolt G, Krhin B, Zaletel K, Gaberscek S.Radiol Oncol. 2024 Jul 22;58(3):357-365. doi: 10.2478/raon-2024-0035. eCollection 2024 Sep 1.PMID: 39042833 Free PMC article.
Saliva samples could be diluted up to 1:8. There was no interference of thiocyanate and caffeine up to 193.5 mg/L. Our original method was comparable to ICP-MS. …17Cite
The role of metals in hypothiocyanite resistance in Escherichia coli.
Gray MJ.J Bacteriol. 2024 Aug 22;206(8):e0009824. doi: 10.1128/jb.00098-24. Epub 2024 Jul 17.PMID: 39016617 Free PMC article.
The innate immune system employs a variety of antimicrobial oxidants to control and kill host-associated bacteria. Hypothiocyanite/hypothiocyanous acid ((-)OSCN/HOSCN) is one such antimicrobial oxidant that is synthesized by lactoperoxidase, myeloperoxidase, and eos …18Cite
Heteronuclear Complexes of Hg(II) and Zn(II) with Sodium Monensinate as a Ligand.
Pantcheva I, Petkov N, Encheva E, Kolev S, Simova S, Tsanev A, Dorkov P, Ugrinov A.Molecules. 2024 Jun 29;29(13):3106. doi: 10.3390/molecules29133106.PMID: 38999058 Free PMC article.
The commercial veterinary antibiotic sodium monensinate (MonNa) binds mercury(II) or zinc(II) cations as thiocyanate [Hg(MonNa)(2)(SCN)(2)] (1) or isothiocyanate [Zn(MonNa)(2)(NCS)(2)] (2) neutral coordination compounds. …Zinc(II) binding does not influence the monensin …19Cite
Quantifying Viable M. tuberculosis Safely Obviating the Need for High Containment Facilities.
Mtafya B, Musisi E, Qwaray P, Sichone E, Walbaum N, Ntinginya NE, Gillespie SH, Sabiiti W.Methods Mol Biol. 2024;2833:145-152. doi: 10.1007/978-1-0716-3981-8_14.PMID: 38949708
In this method, we describe a process of inactivating sputum samples by either heat or guanidine thiocyanate (GTC) that renders them safe without affecting the quantification of viable bacteria. …20Cite
Ali R, Saleh SM.Biosensors (Basel). 2024 Apr 30;14(5):223. doi: 10.3390/bios14050223.PMID: 38785697 Free PMC article.
The surfactant cetyltrimethylammonium bromide (CTAB) induces the aggregation of gold nanoclusters (GNCs), leading to the development of a proposed fluorometric technique for detecting thiocyanate (SCN(-)) ions based on an anti-aggregation mechanism. This approach is straig …21Cite
Nayak M, Sonowal L, Pradhan L, Upadhyay A, Kamath P, Mukherjee S.Chem Asian J. 2024 Nov 4;19(21):e202400187. doi: 10.1002/asia.202400187. Epub 2024 Aug 26.PMID: 38665128
In this article, nickel thiocyanate nanoparticle (NiSCN-NPs) impregnated cotton gauze wound dressing (NiSCN-CG) was developed. …In vivo wound healing studies in rat models using NiSCN-CG demonstrated rapid scarless wound healing. The nickel thiocyanate impregnated …22Cite
RNA Isolation Method in Marginal Crops with High Agronomic Potential.
Casarrubias-Castillo K, Délano-Frier JP, Palmeros-Suárez PA.Methods Mol Biol. 2024;2787:201-207. doi: 10.1007/978-1-0716-3778-4_13.PMID: 38656491
In the method described here, the use of guanidinium thiocyanate and two additional precipitation steps with different reagents designed to obtain high yields and RNA purity levels from diverse plant species employed for plant functional genomics studies is described….23Cite
Polozsányi Z, Galádová H, Kaliňák M, Jopčík M, Kaliňáková B, Breier A, Šimkovič M.Plants (Basel). 2024 Mar 30;13(7):995. doi: 10.3390/plants13070995.PMID: 38611524 Free PMC article.
Research on ITCs that have proven anticancer, antimicrobial, and chemoprotective properties is usually conducted with pure commercially available compounds. …While SFN is stable in aqueous media during the measurement, pHBITC undergoes non-enzymatic hydrolysis to p-hydro …24Cite
The therapeutic potential of thiocyanate and hypothiocyanous acid against pulmonary infections.
Ashtiwi NM, Kim SO, Chandler JD, Rada B.Free Radic Biol Med. 2024 Jul;219:104-111. doi: 10.1016/j.freeradbiomed.2024.04.217. Epub 2024 Apr 11.PMID: 38608822 Free PMC article. Review.
Hypothiocyanous acid (HOSCN) is an endogenous oxidant produced by peroxidase oxidation of thiocyanate (SCN(-)), an ubiquitous sulfur-containing pseudohalide synthesized from cyanide. …This imparts both antioxidant and antimicrobial potential to SCN(-). In this rev …25Cite
Improved SARS-CoV-2 RNA recovery in wastewater matrices using a CTAB-based extraction method.
Ousset MJ, Pianciola LA, Mazzeo M, Oteiza JM, Jaureguiberry MS, Venturino A, Barril PA.J Virol Methods. 2024 Jun;327:114918. doi: 10.1016/j.jviromet.2024.114918. Epub 2024 Mar 29.PMID: 38556176
These methods included CTAB-based, TRIzol-based, and guanidinium thiocyanate (GTC)-based extraction procedures coupled with silica spin column-based purification, and an automated extraction/purification protocol using paramagnetic particles. …26Cite
Palekyte A, Morkowska A, Billington O, Morris-Jones S, Millard J, Marakalala MJ, Owolabi O, Sambou B, Zumla A, Sutherland JS, McHugh TD, Honeyborne I.Clin Chem. 2024 Apr 3;70(4):642-652. doi: 10.1093/clinchem/hvae013.PMID: 38479728
Acetic acid was tested and compared to 4 M guanidine thiocyanate to be simultaneously bactericidal and preserve mycobacterial RNA. The extraction was based on silica column technology and incorporated low-cost reagents: 3 M sodium acetate and ethanol for the RNA extraction …27Cite
Jermusek FA Jr, Webb LJ.Biochemistry. 2024 Jan 2;63(1):27-41. doi: 10.1021/acs.biochem.3c00366. Epub 2023 Dec 11.PMID: 3807882628Cite
Ahmed SR, Sherazee M, Das P, Shalauddin M, Akhter S, Basirun WJ, Srinivasan S, Rajabzadeh AR.Biosens Bioelectron. 2024 Feb 15;246:115857. doi: 10.1016/j.bios.2023.115857. Epub 2023 Nov 24.PMID: 38029708
Herein, the surface of the pristine borophene was first modified with the addition of thiocyanate groups to improve hydroxyl radical (OH) scavenging activity. Then, the oxidation reaction of TMB was accelerated under applied electrochemical potential. …29Cite
Silva-Flores PG, Galindo-Rodríguez SA, Pérez-López LA, Álvarez-Román R.Molecules. 2023 Oct 18;28(20):7142. doi: 10.3390/molecules28207142.PMID: 37894621 Free PMC article.
The antioxidant activity was evaluated using the ferric thiocyanate method. The ex vivo effects on pig skin were evaluated based on biophysical parameters using bioengineering techniques. …30Cite
Park SM, Choi C, Rhee MS.Food Res Int. 2023 Nov;173(Pt 1):113312. doi: 10.1016/j.foodres.2023.113312. Epub 2023 Jul 23.PMID: 37803623
Afterward, 16 DNA purification protocols involving the following steps (steps 2-3) were assessed: the precipitation of meat proteins (step 2; using 2.5, 5.0 M NaCl or 1:1, 2:1 ethanol as the precipitant) and binding of DNA to silicon dioxide particles with chaotropic salts (step …31Cite
Abdelfattah MM, Hosny Y, Elkady NA, Abbas EM, Farahat IG, Hassan NHA, Helwa R.Biochem Genet. 2024 Jun;62(3):1827-1839. doi: 10.1007/s10528-023-10509-3. Epub 2023 Sep 25.PMID: 37747532 Free PMC article.
The homemade phenol-based RNA extraction reagents were prepared using saturated phenol pH 4.3 (adjusted by 0.5 M citrate buffer) and guanidine thiocyanate. To validate the phenol-based reagent, RNA was purified from different biological samples (cell line, tissues, and fun …32Cite
Phosphoproteomics After Guanidinium Thiocyanate Extraction of Tissue Biopsies.
Rolfs F, de Goeij-de Haas RR, Knol JC, Piersma SR, Jimenez CR.Methods Mol Biol. 2023;2718:285-302. doi: 10.1007/978-1-0716-3457-8_16.PMID: 37665466
Focusing on the phosphoproteomic aspect of this workflow, we here provide detailed information on our protocol, which is based on commonly used acid guanidinium thiocyanate-phenol-chloroform (AGPC) extraction with RNA-Bee. We describe the necessary steps for biopsy collect …33Cite
Magacz M, Alatorre-Santamaría S, Kędziora K, Klasa K, Mamica P, Pepasińska W, Lebiecka M, Kościelniak D, Pamuła E, Krzyściak W.Int J Mol Sci. 2023 Jul 28;24(15):12136. doi: 10.3390/ijms241512136.PMID: 37569513 Free PMC article.
The lactoperoxidase (LPO) system shows promise in the prevention of dental caries, a common chronic disease. This system has antimicrobial properties and is part of the non-specific antimicrobial immune system. Understanding the efficacy of the LPO system in the fig …34Cite
Kumar GS, Dubey A, Panda SP, Alawi MM, Sindi AA, Azhar EI, Dwivedi VD, Agrawal S.J Biomol Struct Dyn. 2024 Aug;42(13):6850-6862. doi: 10.1080/07391102.2023.2245059. Epub 2023 Aug 7.PMID: 37551014
Subsequently, three antibiotic drug molecules, i.e., Amikacin hydrate (-66.87 kcal/mol), Isepamicin sulphate (-60.8 kcal/mol), and Bekanamycin (-46.89 kcal/mol), were selected on the basis of their binding free energy value for further computational studies in comparison to refer …35Cite
Chedupaka R, Audipudi AV, Sangolkar AA, Mamidala S, Venkatesham P, Penta S, Vedula RR.Mol Divers. 2024 Jun;28(3):1565-1576. doi: 10.1007/s11030-023-10675-x. Epub 2023 Jul 25.PMID: 37490125
A general and sustainable approach for the synthesis of benzimidazole-thiazole compounds via an efficient, one-pot, domino, pseudo-four-component reaction using 5-amino-2-mercaptobenzimidazole, aralkyl halides, ammonium thiocyanate, and substituted alpha-bromo-acetophenone …36Cite
Biswas S, Wasai A, Ghosh M, Rizzoli C, Roy A, Saha S, Mandal S.J Inorg Biochem. 2023 Oct;247:112314. doi: 10.1016/j.jinorgbio.2023.112314. Epub 2023 Jul 7.PMID: 37478779
In this work, we report a distorted square pyramidal mononuclear copper(II) complex [Cu(L)(NCS)] (1) which was obtained by the reaction of the aqueous solution of ammonium thiocyanate to a methanolic solution of copper nitrate trihydrate and corresponding Schiff-base ligan …37Cite
Optimized Method for Mycobacteria DNA Extraction from Sputum for Isothermal Amplification.
Mun BS, Yoon J, Yoon SY.Ann Clin Lab Sci. 2023 May;53(3):476-481.PMID: 37437925
For DNA adsorption protocol, one-step protocol of adding DNA adsorption solution containing 4.5 M gudanidinium thiocyanate (GuSCN) before thermal lysis and performing DNA purification using spin column showed achieved efficient DNA extraction. …38Cite
Viswanathan V, Ahmad MI, Singh PK, Ahmad N, Sharma P, Sharma S, Singh TP.J Inorg Biochem. 2023 Oct;247:112311. doi: 10.1016/j.jinorgbio.2023.112311. Epub 2023 Jul 3.PMID: 37421730
The previous structural studies have shown that LPO converts substrates, thiocyanate (SCN(-)) and iodide (I(-)) ions into oxidized products, hypothiocyanite (OSCN(-)) and hypoiodite (IO(-)) ions respectively. …39Cite
Li X, Ji Y, Zu T, Huang X, Wang J, Cao Y, Cui Z.Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2023 Aug;40(8):1025-1034. doi: 10.1080/19440049.2023.2227742. Epub 2023 Jul 6.PMID: 37410937
Cyanide and thiocyanate were derivatized with pentafluorobenzyl bromide (PFBBr) as PFB-CN and PFB-SCN, respectively. …The proposed method was validated as a simple, fast and highly sensitive method for the determination of cyanide and thiocyanate in milk….40Cite
Total Bacterial RNA Isolation and Northern Blotting Analysis.
Karlsson J, Eichner H, Loh E.Methods Mol Biol. 2023;2674:73-85. doi: 10.1007/978-1-0716-3243-7_5.PMID: 37258961
The ability to obtain clean and undegraded RNA could be challenging and daunting and remains the most crucial experimental step prior to downstream analyses, such as Northern blotting, quantitative PCR (qPCR), and RNA-seq.This chapter describe two methods (acid guanidinium thi …41Cite
Dual oxidase 1 is dispensable during Mycobacterium tuberculosis infection in mice.
Gupta T, Sarr D, Fantone K, Ashtiwi NM, Sakamoto K, Quinn FD, Rada B.Front Immunol. 2023 Mar 3;14:1044703. doi: 10.3389/fimmu.2023.1044703. eCollection 2023.PMID: 36936954 Free PMC article.
One of the innate defenses used by respiratory epithelial cells to prevent microbial infection is an oxidative antimicrobial system consisting of the proteins, lactoperoxidase (LPO) and Dual oxidase 1 (Duox1), the thiocyanate anion (SCN-) and hydrogen peroxide (H2O2 …42Cite
Azizi M, Abdulrahman YJ, Abdessamad NH, Azzaz AA, Naguib DM.Environ Sci Pollut Res Int. 2023 Apr;30(18):53397-53410. doi: 10.1007/s11356-023-25566-9. Epub 2023 Mar 1.PMID: 36854946
Moreover, the analytical results showed that the two extracts are complex and contained thiocyanic acid, benzene, 3-pyridine carboxaldehyde, benzyl nitrile, ethyl tridecanoate, ethyl oleate, and dodecanoic acid ethyl ester. …43Cite
To Cut the Mustard: Antimicrobial Activity of Selenocyanates on the Plate and in the Gas Phase.
Sarfraz M, Nasim MJ, Gruhlke MCH, Handzlik J, Jacob C.Antibiotics (Basel). 2023 Feb 1;12(2):290. doi: 10.3390/antibiotics12020290.PMID: 36830201 Free PMC article.
Various aromatic selenocyanates have been synthesized and, similar to some of the most Reactive Sulfur Species (RSS), such as allicin, found to be active against a range of bacteria, including Escherichia coli, Pseudomonas syringae and Micrococcus luteus, and fungi, including Ver …44Cite
Hallberg LAE, Barlous K, Hawkins CL.Antioxidants (Basel). 2023 Feb 14;12(2):478. doi: 10.3390/antiox12020478.PMID: 36830036 Free PMC article.
Therefore, studies were extended to examine the efficacy of a range of antioxidant compounds that modulate HOCl production by MPO to prevent NETosis. It was shown that thiocyanate, selenocyanate and various nitroxides could prevent NETosis in PLB-985 neutrophils exposed to …45Cite
Magacz M, Papież M, Kościelniak D, Jurczak A, Kędziora K, Pamuła E, Krzyściak W.Int J Mol Sci. 2023 Jan 30;24(3):2640. doi: 10.3390/ijms24032640.PMID: 36768964 Free PMC article.
Attempts are being made to develop oral hygiene products enriched with various antimicrobial agents. One of them is lactoperoxidase-an enzyme that can oxidise (pseudo)halide ions to reactive products with antimicrobial activity. Currently, commercially availa …46Cite
Zhao Q, Cao J, Cai X, Wang J, Kong F, Wang D, Wang J.Appl Environ Microbiol. 2023 Feb 28;89(2):e0189222. doi: 10.1128/aem.01892-22. Epub 2023 Feb 1.PMID: 36722969 Free PMC article.
Finally, the main volatile compounds were identified by solid-phase microextraction (SPME)-gas chromatography-mass spectroscopy (GC-MS) as S-methyl thioacetate, methyl thiocyanate, methyl disulfide, 1-decene, 2-ethylhexanol, 1,4-undecadiene, 1-undecene, 1,3-benzothiazole, …47Cite
Hypothiocyanite and host-microbe interactions.
Meredith JD, Gray MJ.Mol Microbiol. 2023 Mar;119(3):302-311. doi: 10.1111/mmi.15025. Epub 2023 Feb 6.PMID: 36718113 Free PMC article.
The pseudohypohalous acid hypothiocyanite/hypothiocyanous acid (OSCN(-) /HOSCN) has been known to play an antimicrobial role in mammalian immunity for decades. It is a potent oxidant that kills bacteria but is non-toxic to human cells. Produced from thiocyanate (SCN …48Cite
Xie X, Lei Y, Li Y, Zhang M, Sun J, Zhu MQ, Wang J.J Colloid Interface Sci. 2023 May;637:20-32. doi: 10.1016/j.jcis.2023.01.081. Epub 2023 Jan 18.PMID: 36682115
In this work, a multifunctional bioadhesive hydrogel with double colorimetric-integrated of polyethylene glycol (PVA)-dextran (Dex)-borax-bromothymol blue (BTB)-fluorescein thiocyanate (FITC) and functionalization by tungsten disulfide-catechol nanozyme (CL/WS(2)) was crea …49Cite
King L, Wang Q, Xia L, Wang P, Jiang G, Li W, Huang Y, Liang X, Peng X, Li Y, Chen L, Liu L.Environ Int. 2023 Jan;171:107713. doi: 10.1016/j.envint.2022.107713. Epub 2022 Dec 21.PMID: 36565572 Free article.
BACKGROUND: Evidence on environmental exposure to perchlorate, nitrate, and thiocyanate, three thyroidal sodium iodine symporter (NIS) inhibitors, and thyroid function in the Chinese population remains limited. …Each 1-unit increase in log-transformed urinary thiocyan …50Cite
Akiba Y, Leung AM, Bashir MT, Ebrahimi R, Currier JW, Neverova N, Kaunitz JD.Sci Rep. 2022 Dec 3;12(1):20935. doi: 10.1038/s41598-022-23803-8.PMID: 36463312 Free PMC article.
The lactoperoxidase (LPO)-hydrogen peroxide-halides reaction (LPO system) converts iodide and thiocyanate (SCN(-)) into hypoiodous acid (HOI) and hypothiocyanite (OSCN(-)), respectively. …Institute of Medicine (1,100 g/day) may augment the generation of antimicrobial …51Cite
Łukomska A, Wiśniewska A, Dąbrowski Z, Lach J, Wróbel K, Kolasa D, Domańska U.Molecules. 2022 Aug 5;27(15):4984. doi: 10.3390/molecules27154984.PMID: 35956933 Free PMC article.
Trihexyltetradecylphosphonium bis(2,4,4-trimethylpentyl) phosphinate, [P(6,6,6,14)][Cyanex272], ([P(6,6,6,14)][BTMPP]), trihexyltetradecylphosphonium thiocyanate, [P(6,6,6,14)][SCN], methyltrioctylammonium chloride (Aliquat 336), as well as bis(2,4,4-trimethylpentyl)phosph …52Cite
Hanke M, Hansen N, Tomm E, Grundmeier G, Keller A.Int J Mol Sci. 2022 Aug 1;23(15):8547. doi: 10.3390/ijms23158547.PMID: 35955680 Free PMC article.
Here, we investigated the denaturation of DNA origami nanostructures by three Gdm salts, i.e., guanidinium chloride (GdmCl), guanidinium sulfate (Gdm(2)SO(4)), and guanidinium thiocyanate (GdmSCN), at different temperatures and in dependence of incubation time. Using DNA o …53Cite
Shearer HL, Pace PE, Paton JC, Hampton MB, Dickerhof N.J Biol Chem. 2022 Sep;298(9):102359. doi: 10.1016/j.jbc.2022.102359. Epub 2022 Aug 9.PMID: 35952759 Free PMC article.
Hypothiocyanous acid (HOSCN) is an antimicrobial oxidant produced from hydrogen peroxide and thiocyanate anions by heme peroxidases in secretory fluids such as in the human respiratory tract. …Using deletion mutants, we demonstrate that the HOSCN reductase is disp …54Cite
Candida auris PCR for high-throughput infection control screening.
Crawford LC, Kidd SE, Anninos TM, Turra M, Weldhagen GF.Med Mycol. 2022 Aug 18;60(8):myac057. doi: 10.1093/mmy/myac057.PMID: 35927750
Finally, the use of a lysis buffer comprising 4 m guanidinium thiocyanate rendered swab-equivalent quantities of C. auris non-viable, providing assurance of the safety benefit of PCR over culture. …55Cite
Escherichia coli RclA is a highly active hypothiocyanite reductase.
Meredith JD, Chapman I, Ulrich K, Sebastian C, Stull F, Gray MJ.Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2119368119. doi: 10.1073/pnas.2119368119. Epub 2022 Jul 22.PMID: 35867824 Free PMC article.
HOSCN is abundant in saliva and airway secretions and has long been considered a highly specific antimicrobial that is nearly harmless to mammalian cells. However, certain bacteria, commensal and pathogenic, are able to escape damage by HOSCN and other harmful antimicro …56Cite
Direct Cyanation of Thiophenols or Thiols to Access Thiocyanates under Electrochemical Conditions.
Jiang C, Zhu Y, Li H, Liu P, Sun P.J Org Chem. 2022 Aug 5;87(15):10026-10033. doi: 10.1021/acs.joc.2c00995. Epub 2022 Jul 22.PMID: 35866614
A novel electrochemical cross-coupling method for the synthesis of thiocyanates via the direct cyanation of readily available thiophenols or thiols with trimethylsilyl cyanide (TMSCN) was developed. …External oxidant-free, transition-metal-free and mild operating conditi …57Cite
Lin Y, Cai Q, Luo Y, Li B, Chen Y, Yang X, Xuan Y, Yang H, He R.Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2205574119. doi: 10.1073/pnas.2205574119. Epub 2022 Jul 11.PMID: 35858331 Free PMC article.
Unexpectedly, we found that lack of chemerin-CMKLR1 signaling specifically reduced expression of lactoperoxidase (LPO), a peroxidase that is predominantly expressed in colonic ECs and utilizes H(2)O(2) to oxidize thiocyanates to the antibiotic compound, thereby leading to …58Cite
[On integration of the iodine deficiency elimination and salt reduction programs].
Fedorenko EV, Kolomiets ND, Mokhort TV, Sychik SI, Belysheva LL, Mokhort EG, Petrenko SV.Vopr Pitan. 2022;91(3):53-63. doi: 10.33029/0042-8833-2022-91-3-53-63. Epub 2022 May 4.PMID: 35852978 Russian.
To assess the feasibility of integrating iodine deficiency prevention and salt reduction programmes among the adult population in the Republic of Belarus. Material and methods. Using the thiocyanate-nitrite method, the determination of iodine in various types of foods was …59Cite
The Prevalence and Risk Factors Associated with Iodine Deficiency in Canadian Adults.
Mathiaparanam S, Nori de Macedo A, Mente A, Poirier P, Lear SA, Wielgosz A, Teo KK, Yusuf S, Britz-Mckibbin P.Nutrients. 2022 Jun 21;14(13):2570. doi: 10.3390/nu14132570.PMID: 35807751 Free PMC article.
Herein, we examined the prevalence of iodine deficiency in adults (median age of 61 years) based on the analysis of 24 h urine samples collected from 800 participants in four clinical sites across Canada in the Prospective Urban and Rural Epidemiological (PURE) study. Urinary iod …60Cite
Sakalli B, Basmaci F, Dalmizrak O.BMC Oral Health. 2022 Jun 30;22(1):266. doi: 10.1186/s12903-022-02300-4.PMID: 35773675 Free PMC article.
The penetration of peroxide release was measured using the colorimetric ferric thiocyanate method. Statistical analysis of the data was performed with Three-way ANOVA and Tukey’s test (P = 0.05). …CONCLUSIONS: Peroxide diffusion was significantly influenced by the kind o …61Cite
Xu S, Chuang CY, Malle E, Gamon LF, Hawkins CL, Davies MJ.Free Radic Biol Med. 2022 Aug 1;188:162-174. doi: 10.1016/j.freeradbiomed.2022.06.222. Epub 2022 Jun 16.PMID: 35718304 Free article.
MPO also utilizes H(2)O(2) to oxidize other substrates, and we hypothesized that mixtures of other plasma anions, including bromide (Br(-)), iodide (I(-)), thiocyanate (SCN(-)) and nitrite (NO(2)(-)), at normal or supplemented concentrations, might modulate MPO-mediated HO …62Cite
Ashtiwi NM, Sarr D, Nagy T, Reneer ZB, Tripp RA, Rada B.Front Immunol. 2022 May 18;13:859033. doi: 10.3389/fimmu.2022.859033. eCollection 2022.PMID: 35663985 Free PMC article.63Cite
Plaszkó T, Szűcs Z, Vasas G, Gonda S.Phytochemistry. 2022 Aug;200:113245. doi: 10.1016/j.phytochem.2022.113245. Epub 2022 May 24.PMID: 35623473 Free article. Review.
Though the most widely known glucosinolate decomposition products are the antimicrobial isothiocyanates, there is a wide range of other volatile and non-volatile natural products that arise from this biosynthetic pathway. …It deals with compounds including (1) glucosinol …64Cite
Resistance of Streptococcus pneumoniae to Hypothiocyanous Acid Generated by Host Peroxidases.
Shearer HL, Kaldor CD, Hua H, Kettle AJ, Parker HA, Hampton MB.Infect Immun. 2022 Mar 17;90(3):e0053021. doi: 10.1128/IAI.00530-21. Epub 2022 Jan 18.PMID: 35156851 Free PMC article.
However, the addition of physiological concentrations of thiocyanate protected the bacteria. Similarly, S. pneumoniae remained viable in the presence of lactoperoxidase and thiocyanate even though the majority of bacterial H(2)O(2) was converted to hypothiocyanous a …65Cite
Zepeda B, Verdonk JC.Curr Protoc. 2022 Jan;2(1):e351. doi: 10.1002/cpz1.351.PMID: 35077031
This became particularly problematic during the COVID-19 crisis when supply chains were affected and when RNA extraction and analysis reagents were suddenly scarce at a time when they were particularly required. Acid guanidinium thiocyanate-phenol-chloroform (AGPC) is one …66Cite
Rahin Ahmed S, Sherazee M, Srinivasan S, Reza Rajabzadeh A.Food Chem. 2022 Jun 15;379:132152. doi: 10.1016/j.foodchem.2022.132152. Epub 2022 Jan 15.PMID: 35063843
Thiocyanate (SCN(-)) concentration monitoring in food is important to ensure the health and safety of the consumers.A colorimetric detection of thiocyanate (SCN(-)) based on the nanozymatic activity of gold nanoparticle-graphene quantum dots (GQDs-Au NPs) hybrids in …67Cite
Biocides in antifouling paint formulations currently registered for use.
Paz-Villarraga CA, Castro ÍB, Fillmann G.Environ Sci Pollut Res Int. 2022 Apr;29(20):30090-30101. doi: 10.1007/s11356-021-17662-5. Epub 2022 Jan 8.PMID: 34997484
Cuprous oxide, copper pyrithione, zinc pyrithione, zineb, DCOIT, and cuprous thiocyanate were the most frequent ones, with mean relative concentrations of 35.9 12.8%, 2.9 1.6%, 4.0 5.3%, 5.4 2.0%, 1.9 1.9%, and 18.1 8.0% (w/w) of respective biocide present in the antifouli …68Cite
Bregenzer A, Ottiger C, Krismer C, Sager K, Fux CA.Swiss Med Wkly. 2021 Dec 23;151:w30089. doi: 10.4414/smw.2021.w30089. eCollection 2021 Dec 20.PMID: 34964589 Free article.
For HCV RNA extraction, the whole DBS was cut out with an 18-mm puncher and transferred into 1.3 ml guanidinium thiocyanate-containing buffer (provided by Cepheid). After mixing and incubating at room temperature for 2-3 hours, 1 ml supernatant was analysed with the Xpert …69Cite
Shearer HL, Paton JC, Hampton MB, Dickerhof N.Free Radic Biol Med. 2022 Feb 1;179:24-33. doi: 10.1016/j.freeradbiomed.2021.12.261. Epub 2021 Dec 17.PMID: 3492310170Cite
Reverse Ordered Sequential Mechanism for Lactoperoxidase with Inhibition by Hydrogen Peroxide.
Cupp-Sutton K, Ashby MT.Antioxidants (Basel). 2021 Oct 20;10(11):1646. doi: 10.3390/antiox10111646.PMID: 34829517 Free PMC article.
Lactoperoxidase (LPO, Fe(III) in its resting state in the absence of substrates)-an enzyme secreted from human mammary, salivary, and other mucosal glands-catalyzes the oxidation of thiocyanate (SCN(-)) by hydrogen peroxide (H(2)O(2)) to produce hypothiocyanite (OSCN(-)), …71Cite
Determination of exposure to major iodide ion uptake inhibitors through drinking waters.
Cengiz MF, Sen F, Bilgin AK, Boyaci-Gunduz CP.Environ Res. 2022 Mar;204(Pt D):112345. doi: 10.1016/j.envres.2021.112345. Epub 2021 Nov 10.PMID: 34774300
The transportation can be blocked by some polyatomic anions known as I(-) uptake inhibitors. Perchlorate (ClO(4)(-)), thiocyanate (SCN(-)) and nitrate (NO(3)(-)) are reported as the major I(-) uptake inhibitors and exposure could be through various routes. …72Cite
Singh PK, Ahmad N, Yamini S, Singh RP, Singh AK, Sharma P, Smith ML, Sharma S, Singh TP.Protein Sci. 2022 Feb;31(2):384-395. doi: 10.1002/pro.4230. Epub 2021 Nov 18.PMID: 34761444 Free PMC article.
To perform its innate immune action against invading microbes, LPO utilizes hydrogen peroxide (H(2) O(2) ) to convert thiocyanate (SCN(-) ) and iodide (I(-) ) ions into the oxidizing compounds hypothiocyanite (OSCN(-) ) and hypoiodite (IO(-) ). …73Cite
Welk A, Patjek S, Gärtner M, Baguhl R, Schwahn C, Below H.BMC Microbiol. 2021 Nov 3;21(1):302. doi: 10.1186/s12866-021-02333-9.PMID: 34732139 Free PMC article. Clinical Trial.
BACKGROUND: Antimicrobial agents are considered valuable adjuncts to mechanical methods of plaque control. …Therefore, using physiological substances is promising due to no risk of development, for example, of microbial resistances, allergies or DNA damaging. The …74Cite
Tomar SK, Kumar R, Chakraborty S.J Hazard Mater. 2022 Jan 15;422:126861. doi: 10.1016/j.jhazmat.2021.126861. Epub 2021 Aug 11.PMID: 34403942
Aerobic granular sludge potential for concurrent biodegradation of two nitrogenous heterocyclic compounds (NHCs), i.e., pyridine and indole, and ammonia nitrogen along with phenol and thiocyanate was investigated in three sequencing batch reactors (SBRs) (R1, R2, and R3). …75Cite
Honeywood MJ, Jeffries-Miles S, Wong K, Harrington C, Burns CC, Oberste MS, Bowen MD, Vega E.J Virol Methods. 2021 Nov;297:114262. doi: 10.1016/j.jviromet.2021.114262. Epub 2021 Aug 9.PMID: 34384823 Free PMC article.
In this study, we investigated the use of guanidine thiocyanate-based nucleic acid extraction buffers from commercially available nucleic acid extraction kits to inactivate poliovirus in cell culture isolates and stool suspensions, two common types of poliovirus IM and PIM …76Cite
Charmforoshan E, Karimi E, Oskoueian E, Iranshahi M.Nutr Cancer. 2022;74(5):1829-1836. doi: 10.1080/01635581.2021.1962922. Epub 2021 Aug 11.PMID: 34378465
The nitric oxide scavenging activity (IC(50): 670.9 g/ml) showed its moderate antioxidant potential. Similarly, the results of ferric thiocyanate and thiobarbituric acid assays reconfirmed the moderate antioxidant activity of auraptene and indicated the percentage inhibiti …77Cite
Lactose oxidase: An enzymatic approach to inhibit Listeria monocytogenes in milk.
Flynn BT, Kozak SM, Lawton MR, Alcaine SD.J Dairy Sci. 2021 Oct;104(10):10594-10608. doi: 10.3168/jds.2021-20450. Epub 2021 Jul 30.PMID: 34334205 Free article.
Lactose oxidase (LO) is a microbial-derived enzyme with antimicrobial properties. It oxidizes lactose into lactobionic acid and reduces oxygen, generating H(2)O(2). …These LO treatments were then applied to raw milk with various modifications; higher levels of LO as well …78Cite
Efficient method for isolation of high-quality RNA from Psidium guajava L. tissues.
Carpinetti PA, Fioresi VS, Ignez da Cruz T, de Almeida FAN, Canal D, Ferreira A, Ferreira MFDS.PLoS One. 2021 Jul 26;16(7):e0255245. doi: 10.1371/journal.pone.0255245. eCollection 2021.PMID: 34310664 Free PMC article.
Here, quality and yields of RNA isolates were compared using six extraction protocols: two protocols based on the application of cetyltrimethylammonium bromide (CTAB) lysis buffer, one protocol which uses the TRIzol reagent, one which applies guanidine thiocyanate lysis bu …79Cite
Flynn B, deRiancho D, Lawton MR, Alcaine SD.Foods. 2021 Jun 25;10(7):1471. doi: 10.3390/foods10071471.PMID: 34201990 Free PMC article.
Lab-scale queso fresco was produced and inoculated with L. monocytogenes at final concentrations of 1 log CFU/mL and 1 CFU/100 mL. LO and LO sodium thiocyanate (TCN) combinations were incorporated into the milk or topically applied to the finished cheese product in varying …80Cite
Evaluation of stability and inactivation methods of SARS-CoV-2 in context of laboratory settings.
Widera M, Westhaus S, Rabenau HF, Hoehl S, Bojkova D, Cinatl J Jr, Ciesek S.Med Microbiol Immunol. 2021 Aug;210(4):235-244. doi: 10.1007/s00430-021-00716-3. Epub 2021 Jul 1.PMID: 34196781 Free PMC article.
In addition, lysates of infected cells and virus containing supernatant were subjected to RT-qPCR analysis. We have found that guanidine thiocyanate and most of the tested detergent containing lysis buffers were effective in inactivation of SARS-CoV-2, however, the M-PER l …81Cite
Dual oxidase 1 promotes antiviral innate immunity.
Sarr D, Gingerich AD, Asthiwi NM, Almutairi F, Sautto GA, Ecker J, Nagy T, Kilgore MB, Chandler JD, Ross TM, Tripp RA, Rada B.Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2017130118. doi: 10.1073/pnas.2017130118.PMID: 34168077 Free PMC article.
While a line of prior in vitro observations suggested that DUOX1 works in partnership with an airway peroxidase, lactoperoxidase (LPO), to produce antimicrobial hypothiocyanite (OSCN(-)) in the airways, the in vivo role of DUOX1 in mammalian organisms has remained unproven …82Cite
Deletion of the lactoperoxidase gene causes multisystem inflammation and tumors in mice.
Yamakaze J, Lu Z.Sci Rep. 2021 Jun 14;11(1):12429. doi: 10.1038/s41598-021-91745-8.PMID: 34127712 Free PMC article.
Lactoperoxidase (LPO) catalyzes the redox reaction of reducing highly reactive H(2)O(2) to H(2)O while oxidizing thiocyanate (SCN(-)) to relatively tissue-innocuous hypothiocyanite (OSCN(-)). SCN(-) is the only known natural, effective reducing-substrate of LPO; humans nor …83Cite
Anion inhibition studies of the α-carbonic anhydrases from Neisseria gonorrhoeae.
Nocentini A, Hewitt CS, Mastrolorenzo MD, Flaherty DP, Supuran CT.J Enzyme Inhib Med Chem. 2021 Dec;36(1):1061-1066. doi: 10.1080/14756366.2021.1929202.PMID: 34030562 Free PMC article.
Anions/small molecules such as cyanate, thiocyanate, nitrite, nitrate, bisulphite, sulphate, hydrogensulfide, phenylboronic acid, phenylarsonic acid, selenate, tellurate, tetraborate, perrhenate, peroxydisulfate, selenocyanate, iminodisulfonate, and fluorosulfonate showed …84Cite
Preliminary investigation on iodine nutrition in captive giant pandas.
Yao Y, Xu Q, He X, Wang H, Yan H, Gao J, Hou R, Li X, Wang H.J Trace Elem Med Biol. 2021 Sep;67:126780. doi: 10.1016/j.jtemb.2021.126780. Epub 2021 May 18.PMID: 34023729 Free article.
Next, the urinary iodine (UI) and urinary thiocyanate (UT) levels of infant, sub-adult, adult and geriatric captive giant pandas was measured during the periods when the pandas consume both bamboo leaves- and culm (bamboo leaf-culm stage). …CONCLUSIONS: Our results indic …85Cite
Oral peroxidases: From antimicrobial agents to ecological actors (Review).
Courtois P.Mol Med Rep. 2021 Jul;24(1):500. doi: 10.3892/mmr.2021.12139. Epub 2021 May 13.PMID: 33982776 Free PMC article. Review.
In the presence of hydrogen peroxide (H(2)O(2)), oral peroxidases catalyze the oxidation of the pseudohalide anion thiocyanate (SCN(-)) to hypothiocyanite (OSCN(-)), a strong oxidant that serves an antimicrobial role. …86Cite
Phenolic Compounds of Reynoutria sp. as Modulators of Oral Cavity Lactoperoxidase System.
Magacz M, Oszajca M, Nawrot-Hadzik I, Drożdż R, Jurczak A, Hadzik J, Smakosz A, Krzyściak W.Antioxidants (Basel). 2021 Apr 26;10(5):676. doi: 10.3390/antiox10050676.PMID: 33926051 Free PMC article.
Lactoperoxidase (LPO) together with its (pseudo)halogenation cycle substrates, H(2)O(2) and thiocyanate ions oxidized to hypothiocyanite ions, form one of the main systems involved in antimicrobial defense within the oral cavity. …Finally, the ability to enhance t …87Cite
Mannai S, Benfradj N, Karoui A, Salem IB, Fathallah A, M’Hamdi M, Boughalleb-M’Hamdi N.Molecules. 2021 Apr 23;26(9):2479. doi: 10.3390/molecules26092479.PMID: 33922854 Free PMC article.
The in vitro test of three aqueous extract doses of R. raphanistrum against some apple and peach decline agents showed its efficacy in reducing mycelia growth. The in vivo assay of fine powder of this plant on peach seedlings revealed that treatment 8-weeks before the inoc …88Cite
Singh PK, Sharma P, Bhushan A, Kaur P, Sharma S, Singh TP.J Inorg Biochem. 2021 Jul;220:111461. doi: 10.1016/j.jinorgbio.2021.111461. Epub 2021 Apr 18.PMID: 33882424
Lactoperoxidase (LPO) is a mammalian heme peroxidase which catalyzes the conversion of thiocyanate (SCN) and iodide (I(-)) by hydrogen peroxide (H(2)O(2)) into antimicrobial hypothiocyanite (OSCN) and hypoiodite (IO(-)). …89Cite
Rolfs F, Piersma SR, Dias MP, Jonkers J, Jimenez CR.Mol Cell Proteomics. 2021;20:100078. doi: 10.1016/j.mcpro.2021.100078. Epub 2021 Apr 2.PMID: 33819647 Free PMC article.
Although lysis of cells and tissues with urea is widely used for phosphoproteomic applications, DNA, RNA, and proteins can be simultaneously extracted from small samples using acid guanidinium thiocyanate-phenol-chloroform (AGPC). Use of AGPC for mass spectrometry-based ph …90Cite
Manimaran P, Balasubramaniyan S, Azam M, Rajadurai D, Al-Resayes SI, Mathubala G, Manikandan A, Muthupandi S, Tabassum Z, Khan I.Molecules. 2021 Feb 5;26(4):823. doi: 10.3390/molecules26040823.PMID: 33562489 Free PMC article.
2,4-Dinitrophynylhydrazine and two thiocyanate ions in a (M:L1:L2) 1:2:2 molar ratio was synthesized in the complexes of Co(II) and Ni(II). …The in-vitro biological activity of the ligand and the metal complexes were screened against the Gram-positive and negative pathog …91Cite
Kang G, Jing Y, Liu W, Zhang C, Lu L, Chen C, Lu Y.Analyst. 2021 Mar 7;146(5):1650-1655. doi: 10.1039/d1an00002k. Epub 2021 Feb 1.PMID: 33522553
In this work, a novel convenient colorimetric method for sensitive detection of thiocyanate (SCN(-)) has been developed based on its suppression of the oxidase-like activity of palladium square nanoplates on reduced graphene oxide (Pd SP@rGO). …92Cite
Singh PK, Pandey S, Rani C, Ahmad N, Viswanathan V, Sharma P, Kaur P, Sharma S, Singh TP.J Biol Inorg Chem. 2021 Feb;26(1):149-159. doi: 10.1007/s00775-020-01844-6. Epub 2021 Jan 11.PMID: 33427997
Lactoperoxidase, a heme-containing glycoprotein, catalyzes the oxidation of thiocyanate by hydrogen peroxide into hypothiocyanite which acts as an antibacterial agent. …93Cite
Singh LH, Chandra AK, Yumnam SD, Sarkar D, Manglem RK, Dhabali T, Mookerjee S, Ray I.Ecotoxicol Environ Saf. 2021 Jan 15;208:111711. doi: 10.1016/j.ecoenv.2020.111711. Epub 2020 Dec 7.PMID: 33396042 Free article.
METHODS: Goiter survey conducted in children and women of reproductive ages by palpation followed by measurement of urinary iodine, thiocyanate and house-hold salt iodine to evaluate iodine nutritional status and consumption pattern of bamboo-shoots (BS). …CONCLUSIONS: G …94Cite
Structure of Yak Lactoperoxidase at 1.55 Å Resolution.
Viswanathan V, Rani C, Ahmad N, Singh PK, Sharma P, Kaur P, Sharma S, Singh TP.Protein J. 2021 Feb;40(1):8-18. doi: 10.1007/s10930-020-09957-2. Epub 2021 Jan 3.PMID: 33389415
It is secreted from mammary, salivary, lachrymal and mucosal glands. It catalyses the conversion of thiocyanate into hypothiocyanate and halides into hypohalides. LPO belongs to the superfamily of mammalian heme peroxidases which also includes myeloperoxidase (MPO), eosino …95Cite
Torii S, Furumai H, Katayama H.Sci Total Environ. 2021 Feb 20;756:143067. doi: 10.1016/j.scitotenv.2020.143067. Epub 2020 Oct 17.PMID: 33131851 Free PMC article.
This study aims (1) to compare the whole process recovery of Pseudomonas phage phi6, a surrogate for enveloped viruses, among combinations of primary concentration [ultrafiltration (UF), electronegative membrane vortex (EMV), and polyethylene glycol precipitation (PEG)] and RNA e …96Cite
Farrant KV, Spiga L, Davies JC, Williams HD.J Bacteriol. 2020 Dec 18;203(2):e00300-20. doi: 10.1128/JB.00300-20. Print 2020 Dec 18.PMID: 33106346 Free PMC article.
Once established, P. aeruginosa infections persist and are rarely eradicated despite host immune cells producing antimicrobial oxidants, including hypochlorous acid (HOCl) and hypothiocyanous acid (HOSCN). …To combat infection, the host’s immune system produces the an …97Cite
Catao ECP, Gallois N, Fay F, Misson B, Briand JF.Environ Pollut. 2021 Jan 1;268(Pt A):115835. doi: 10.1016/j.envpol.2020.115835. Epub 2020 Oct 14.PMID: 33099201
The two coatings differed in metals composition, either Cu thiocyanate and Zn pyrithione (A3) or Cu2O (Hy). Metal resistance genes (MRG) specific to copper (cusA, copA, cueO) or other metals (czcA and pbrT) were monitored with qPCR in parallel to the microbial community us …98Cite
Antimicrobials offered from nature: Peroxidase-catalyzed systems and their mimics.
Tonoyan L, Montagner D, Friel R, O’Flaherty V.Biochem Pharmacol. 2020 Dec;182:114281. doi: 10.1016/j.bcp.2020.114281. Epub 2020 Oct 17.PMID: 33075313 Free article. Review.
The control of antimicrobial resistance requires the development of novel antimicrobial alternatives and naturally occurring peroxidase-catalyzed systems may be of great value in this era of emerging antimicrobial resistance. …Particular attention is paid t …99Cite
Urbański LJ, Angeli A, Hytönen VP, Di Fiore A, Parkkila S, De Simone G, Supuran CT.J Inorg Biochem. 2020 Dec;213:111274. doi: 10.1016/j.jinorgbio.2020.111274. Epub 2020 Oct 7.PMID: 33068968
Here we investigated the inhibition of TvaCA1 with inorganic anions and small molecules and observed that thiocyanate, cyanide, selenite, selenocyanate and divanadate are sub-millimolar inhibitors, whereas sulfamide, sulfate, phenylboronic acid and phenylarsonic acid are m …100Cite
Familial Aggregation of Endemic Congenital Hypothyroidism Syndrome in Congo (DR): Historical Data.
Weichenberger CX, Rivera MT, Vanderpas J.Nutrients. 2020 Oct 2;12(10):3021. doi: 10.3390/nu12103021.PMID: 33023116 Free PMC article.
Besides severe iodine deficiency, environmental exposure to thiocyanate overload and selenium deficiency, factors not randomly distributed within families and population, intervened in the full expression of endemic CH. …101Cite
Vanichkitrungruang S, Chuang CY, Hawkins CL, Davies MJ.Redox Biol. 2020 Sep;36:101641. doi: 10.1016/j.redox.2020.101641. Epub 2020 Jul 9.PMID: 32863239 Free PMC article.
The effect of increasing concentrations of the alternative MPO substrate thiocyanate (SCN(-)), which might decrease HOCl formation were also examined. Exposure of fibronectin to MPO/H(2)O(2)/Cl(-) is shown to result in damage to the functionally important cell-binding and …102Cite
Kalin R, Köksal Z, Bayrak S, Gerni S, Ozyürek IN, Usanmaz H, Karaman M, Atasever A, Özdemir H, Gülçin İ.J Biomol Struct Dyn. 2022 Jan;40(1):401-410. doi: 10.1080/07391102.2020.1814416. Epub 2020 Aug 28.PMID: 32856529
In metabolism, LPO has ability to catalyze the transformation of thiocyanate (SCN(-)) to hypothiocyanite (OSCN(-)) that is an antibacterial agent and the reaction occurs with hydrogen peroxide. …103Cite
Yu XZ, Chu YP, Zhang H, Lin YJ, Tian P.Ecotoxicology. 2021 Oct;30(8):1511-1520. doi: 10.1007/s10646-020-02266-5. Epub 2020 Aug 21.PMID: 32821975104Cite
Overcoming the undetected inhibition of bone DNA extracts obtained by total demineralization.
Saragoni VG, Celis RC, Intriago M, Melillán-Sanzana AA, Reyes P, Prieto L, Gill P.Forensic Sci Int Genet. 2020 Sep;48:102363. doi: 10.1016/j.fsigen.2020.102363. Epub 2020 Jul 31.PMID: 32769056 No abstract available.105Cite
Gingerich AD, Doja F, Thomason R, Tóth E, Bradshaw JL, Douglass MV, McDaniel LS, Rada B.PLoS One. 2020 Jul 30;15(7):e0236389. doi: 10.1371/journal.pone.0236389. eCollection 2020.PMID: 32730276 Free PMC article.
Airway epithelial cells, the primary responders to pneumococcal infection, orchestrate an extracellular antimicrobial system consisting of lactoperoxidase (LPO), thiocyanate anion and hydrogen peroxide (H2O2). LPO oxidizes thiocyanate using H2O2 into the fina …106Cite
Tomar SK, Chakraborty S.Bioresour Technol. 2020 Nov;315:123824. doi: 10.1016/j.biortech.2020.123824. Epub 2020 Jul 13.PMID: 32688255
Two sequencing batch reactors inoculated with two different kinds of industrial sludge; refinery sludge (R1) and brewery sludge (R2), were operated to observe the impact of high phenol loading (5.71 kg COD m(-3) day(-1)) along with 100 mg L(-1) of ammonia-nitrogen and thiocyan …107Cite
Turan A, Keyikoglu R, Kobya M, Khataee A.Chemosphere. 2020 Sep;255:127014. doi: 10.1016/j.chemosphere.2020.127014. Epub 2020 May 10.PMID: 32679632
This study presents the removal of thiocyanate (SCN(-)) from coke oven wastewater by the electrooxidation (EO) process. Initially, the performances boron-doped diamond (BDD) and different DSA (Dimensionally stable anode) electrodes including Ti/IrO(2), Ti/IrO(2)-RuO(2), an …108Cite
Ulfig A, Leichert LI.Cell Mol Life Sci. 2021 Jan;78(2):385-414. doi: 10.1007/s00018-020-03591-y. Epub 2020 Jul 13.PMID: 32661559 Free PMC article. Review.
Neutrophils are predominant immune cells that protect the human body against infections by deploying sophisticated antimicrobial strategies including phagocytosis of bacteria and neutrophil extracellular trap (NET) formation. …109Cite
The Single-Step Method of RNA Purification Applied to Leptospira.
Zavala-Alvarado C, Benaroudj N.Methods Mol Biol. 2020;2134:41-51. doi: 10.1007/978-1-0716-0459-5_5.PMID: 32632858 Free article.
Here, we describe an application of the effective single-step method of RNA extraction (or guanidinium thiocyanate-phenol-chloroform extraction) applied to Leptospira species. This method is based on the powerful ability of guanidinium thiocyanate to inactivate RNas …110Cite
Environment-Wide Association Study of CKD.
Lee J, Oh S, Kang H, Kim S, Lee G, Li L, Kim CT, An JN, Oh YK, Lim CS, Kim DK, Kim YS, Choi K, Lee JP.Clin J Am Soc Nephrol. 2020 Jun 8;15(6):766-775. doi: 10.2215/CJN.06780619. Epub 2020 May 22.PMID: 32628126 Free PMC article.
A total of 23 chemicals, including serum perfluorooctanoic acid, seven urinary metals, three urinary arsenics, urinary nitrate and thiocyanate, three urinary polycyclic aromatic hydrocarbons, and seven volatile organic compounds, were associated with lower risks of one or …111Cite
Pei Y, Mamtimin T, Ji J, Khan A, Kakade A, Zhou T, Yu Z, Zain H, Yang W, Ling Z, Zhang W, Zhang Y, Li X.Microb Biotechnol. 2021 Mar;14(2):465-478. doi: 10.1111/1751-7915.13615. Epub 2020 Jun 23.PMID: 32578381 Free PMC article.
However, extracting sufficient and high-quality total microbial RNA from seriously heavy metal-contaminated soils is still a challenge. In this study, the guanidine thiocyanate-high EDTA (GTHE) method was established and optimized for recovering high quantity and quality o …112Cite
Sung H, Roh KH, Hong KH, Seong MW, Ryoo N, Kim HS, Lee J, Kim SY, Ryu SW, Kim MN, Han MG, Lee SW, Lee H, Yoo CK.Ann Lab Med. 2020 Nov;40(6):439-447. doi: 10.3343/alm.2020.40.6.439. Epub 2020 Jun 17.PMID: 32539299 Free PMC article.113Cite
Investigating hypothiocyanite against SARS-CoV-2.
Cegolon L.Int J Hyg Environ Health. 2020 Jun;227:113520. doi: 10.1016/j.ijheh.2020.113520. Epub 2020 Apr 6.PMID: 32305009 Free PMC article. No abstract available.114Cite
Hussain A, Pu H, Sun DW.Spectrochim Acta A Mol Biomol Spectrosc. 2020 Mar 15;229:117994. doi: 10.1016/j.saa.2019.117994. Epub 2019 Dec 29.PMID: 31951941
A cysteamine functionalized core shelled nanoparticles (Au@Ag-CysNPs) was presented for simultaneous and rapid detection of sodium thiocyanate (STC) and benzoic acid (BA) preservatives in liquid milk using surface-enhanced Raman spectroscopy (SERS) technique. …115Cite
Afreen G, Shoeb M, Upadhyayula S.Mater Sci Eng C Mater Biol Appl. 2020 Mar;108:110372. doi: 10.1016/j.msec.2019.110372. Epub 2019 Nov 1.PMID: 31924024
A facile synthetic route is presented to produce reduced graphene oxide/CdS quantum dot (rGO/CdS QD) heterostructure by monowave-assisted solvothermal method where room temperature ionic liquid 1-ethyl-3-methylimidazolium thiocyanate serves as a “green” precursor. The prep …116Cite
Tonoyan L, Friel R, O’Flaherty V.J Glob Antimicrob Resist. 2020 Sep;22:13-17. doi: 10.1016/j.jgar.2019.12.007. Epub 2019 Dec 16.PMID: 31857249 Free article.
OBJECTIVES: Antimicrobials, at sub-lethal concentrations, can act as selectors and promoters of resistance by increasing mutation rates. We measured the rate of Escherichia coli mutation from levofloxacin (LVX) sensitivity to resistance when it was grown under the near-let …117Cite
Day BJ, Bratcher PE, Chandler JD, Kilgore MB, Min E, LiPuma JJ, Hondal RJ, Nichols DP.Free Radic Biol Med. 2020 Jan;146:324-332. doi: 10.1016/j.freeradbiomed.2019.11.016. Epub 2019 Nov 15.PMID: 31740228 Free PMC article.
A hallmark of cystic fibrosis (CF) lung pathology is an increased susceptibility to pulmonary infections. Thiocyanate ((-)SCN) is an endogenous component of the innate immunity’s peroxidase system that converts (-)SCN to the antimicrobial agent hypothiocyanite (HOSC …118Cite
Jahanbakhsh S, Dekhne MS, Kohan-Ghadr HR, Bai D, Awonuga A, Morris RT, Yang Z, Abu-Soud HM.J Inorg Biochem. 2020 Feb;203:110911. doi: 10.1016/j.jinorgbio.2019.110911. Epub 2019 Nov 12.PMID: 31734539
Here, we show that mesna (sodium-2-mercaptoethane sulfonate), primarily used to prevent nephrotoxicity and urinary tract toxicity caused by chemotherapeutic agents such as cyclophosphamide and ifosfamide, modulates the catalytic activity of lactoperoxidase (LPO) by binding …119Cite
Rapid DNA detection using filter paper.
Song Y, Gyarmati P.N Biotechnol. 2020 Mar 25;55:77-83. doi: 10.1016/j.nbt.2019.10.005. Epub 2019 Oct 14.PMID: 31622785
It can be used as a POC device, in particular for diagnosis and treatment management of infectious diseases and identification of antimicrobial drug resistance genes….120Cite
mSphere of Influence: Modifying an Old Method To Study RNA-Protein Interactions.
Tiengwe C.mSphere. 2019 Sep 4;4(5):e00600-19. doi: 10.1128/mSphere.00600-19.PMID: 31484744 Free PMC article.
(Nat Biotechnol 37:169-178, 2019, https://doi.org/10.1038/s41587-018-0001-2) influenced his research by providing a tool to capture RNA-protein complexes on a global scale using acid guanidinium thiocyanate-phenol-chloroform (AGPC), an old method hitherto applied for RNA, …121Cite
Ito Y, Touyama A, Uku M, Egami H, Hamashima Y.Chem Pharm Bull (Tokyo). 2019;67(9):1015-1018. doi: 10.1248/cpb.c19-00352.PMID: 31474724 Free article.
Thiocyanation of aromatic compounds has been investigated using the combination of 1-chloro-1,2-benziodoxol-3-(1H)-one (1) and (trimethylsilyl)isothiocyanate (TMSNCS). The reaction with electron rich aromatic compounds proceeded smoothly to provide the thiocyanated …122Cite
Analytical Comparison of Methods for Extraction of Short Cell-Free DNA from Urine.
Oreskovic A, Brault ND, Panpradist N, Lai JJ, Lutz BR.J Mol Diagn. 2019 Nov;21(6):1067-1078. doi: 10.1016/j.jmoldx.2019.07.002. Epub 2019 Aug 20.PMID: 31442674 Free PMC article.
We compared the analytical performance of two published protocols (Wizard resin/guanidinium thiocyanate and Q Sepharose), three commercial kits (Norgen, QIAamp, and MagMAX), and an in-house sequence-specific hybridization capture technique. …Hybridization capture and Q S …123Cite
Lara-Aguilar S, Alcaine SD.J Dairy Sci. 2019 Sep;102(9):7807-7812. doi: 10.3168/jds.2019-16757. Epub 2019 Jul 17.PMID: 31326180 Free article.
A commercially available solution of lactose oxidase was applied at different concentrations (0, 0.12, 1.2, and 12 g/L) in 4 types of media [brain heart infusion agar (BHI), BHI + sodium thiocyanate (NaSCN), BHI + lactose, and BHI + NaSCN + lactose] to evaluate the effect …124Cite
Al-Baarri AN, Damayanti NT, Legowo AM, Tekiner İH, Hayakawa S.Int J Food Sci. 2019 Apr 23;2019:8013402. doi: 10.1155/2019/8013402. eCollection 2019.PMID: 31179314 Free PMC article.
The enzymatic reaction involving lactoperoxidase, thiocyanate, and hydrogen peroxide was used to generate the antibacterial agent from LPOS. …This result may lead to a method for enhancement of the antimicrobial activity of LPOS in milk and derived products….125Cite
Cherkaoui A, Cherpillod P, Renzi G, Schrenzel J, Kaiser L, Schibler M.Clin Microbiol Infect. 2019 Oct;25(10):1289.e1-1289.e4. doi: 10.1016/j.cmi.2019.05.021. Epub 2019 Jun 6.PMID: 31175961 Free article.
METHODS: The accuracy of the FilmArray Blood Culture Identification Panel (BCID) assay was assessed to identify the common bacterial and fungal pathogens associated with bloodstream infections after positive blood culture inactivation using a guanidinium thiocyanate contai …126Cite
Raper E, Stephenson T, Fisher R, Anderson DR, Soares A.Bioresour Technol. 2019 Sep;288:121524. doi: 10.1016/j.biortech.2019.121524. Epub 2019 May 22.PMID: 31154279
Microbial degradation of thiocyanate (SCN(-)) has been reported to suffer from instability highlighting the need for improved understanding of underlying mechanisms and boundaries. …An uncultured species of Thiobacillus was the most abundant species (26%) and displayed s …127Cite
The preservative 2-(thiocyanomethylthio)benzothiazole: A potential allergen in leather products.
Herman A, Goossens A, Tennstedt D, Bergendorff O, Isaksson M, Mowitz M, Baeck M.Contact Dermatitis. 2019 Oct;81(4):262-265. doi: 10.1111/cod.13295. Epub 2019 May 31.PMID: 31006870
BACKGROUND: Allergic contact dermatitis caused by leather is common, and several responsible allergens, such as tanning agents, glues, mercaptobenzothiazole derivatives, and dyes, but also antimicrobials and antifungals, are involved. …128Cite
Rafińska K, Pomastowski P, Rudnicka J, Krakowska A, Maruśka A, Narkute M, Buszewski B.Food Chem. 2019 Aug 15;289:16-25. doi: 10.1016/j.foodchem.2019.03.025. Epub 2019 Mar 11.PMID: 30955598
GC/MS analysis showed that SFE extract from dried sprouts of L. sativum was especially rich in such glucosinolate derivatives as benzyl cyanide and benzyl thiocyanate. However, the extract obtained from freeze-dried sprouts by SFE with addition of 96% ethanol as co-solvent …129Cite
Zietzer A, Niepmann ST, Camara B, Lenart MA, Jansen F, Becher MU, Andrié R, Nickenig G, Tiyerili V.PLoS One. 2019 Apr 2;14(4):e0214476. doi: 10.1371/journal.pone.0214476. eCollection 2019.PMID: 30939159 Free PMC article.
ROS formation by myeloperoxidase, a key enzyme in H2O2 degradation, can be modulated by addition of sodium thiocyanate (NaSCN). However, the therapeutic use of NaSCN to counteract atherogenesis has been controversial, because MPO oxidizes NaSCN to hypothiocyanous acid, whi …130Cite
Magacz M, Kędziora K, Sapa J, Krzyściak W.Int J Mol Sci. 2019 Mar 21;20(6):1443. doi: 10.3390/ijms20061443.PMID: 30901933 Free PMC article. Review.
The main role of this enzyme is to oxidize salivary thiocyanate ions (SCN(-)) in the presence of hydrogen peroxide (H2O2) to products that exhibit antimicrobial activity. …131Cite
The science of licking your wounds: Function of oxidants in the innate immune system.
Day BJ.Biochem Pharmacol. 2019 May;163:451-457. doi: 10.1016/j.bcp.2019.03.013. Epub 2019 Mar 13.PMID: 30876918 Review.
Saliva is thought to have healing properties due to it containing many agents that have antimicrobial properties. A number of these components make up the innate immune system’s oxidant generating network. …LPO utilizes hydrogen peroxide (H(2)O(2)) and the pseudoh …132Cite
Further insights of selenium-containing analogues of WC-9 against Trypanosoma cruzi.
Chao MN, Lorenzo-Ocampo MV, Szajnman SH, Docampo R, Rodriguez JB.Bioorg Med Chem. 2019 Apr 1;27(7):1350-1361. doi: 10.1016/j.bmc.2019.02.039. Epub 2019 Feb 19.PMID: 30808607 Free PMC article.
As a continuation of our project aimed at searching for new chemotherapeutic agents against American trypanosomiasis (Chagas disease), new selenocyanate derivatives were designed, synthesized and biologically evaluated against the clinically more relevant dividing form of …133Cite
Tonoyan L, Fleming GTA, Friel R, O’Flaherty V.Sci Rep. 2019 Feb 20;9(1):2401. doi: 10.1038/s41598-019-38925-9.PMID: 30787338 Free PMC article.
We attempted to generate de novo resistance to a newly described biocidal complex, ITC (iodo-thiocyanate complex), and to levofloxacin (LVX) in Escherichia coli ATCC 25922, by means of selective chemostat culture. We measured resistance by determining the minimum inhibitor …134Cite
Bhattacharya U, Chandra AK.J Pediatr Endocrinol Metab. 2019 Feb 25;32(2):143-149. doi: 10.1515/jpem-2018-0344.PMID: 30710486
Methods Clinical examinations of the goiter, median urinary iodine (MUI), mean urinary thiocyanate (MUSCN) in SAC (6-12 years) from both sexes in the different socioeconomic groups were carried out and the iodine content of edible salt was measured. …135Cite
Electrochemical Assays and Immunoassays of the Myeloperoxidase/SCN–/H2O2 System.
Bekhit M, Gorski W.Anal Chem. 2019 Feb 19;91(4):3163-3169. doi: 10.1021/acs.analchem.8b05855. Epub 2019 Feb 7.PMID: 30689356136Cite
Removal of cyanide adsorbed on pyrite by H2O2 oxidation under alkaline conditions.
Tu Y, Han P, Wei L, Zhang X, Yu B, Qian P, Ye S.J Environ Sci (China). 2019 Apr;78:287-292. doi: 10.1016/j.jes.2018.10.013. Epub 2018 Nov 14.PMID: 30665647
The removal of cyanide adsorbed on pyrite by H(2)O(2) oxidation under alkaline conditions was due to the oxidation of pyrite. Hexacyanoferrate, thiocyanate and sulfate were generated with mole ratios of about 2.03:1.12:3.17 during the cyanide removal….137Cite
Additives for Efficient Biodegradable Antifouling Paints.
Faÿ F, Gouessan M, Linossier I, Réhel K.Int J Mol Sci. 2019 Jan 16;20(2):361. doi: 10.3390/ijms20020361.PMID: 30654517 Free PMC article.
Efficient paints based on biodegradable polymer and with no organic biocide could be obtained by mixing copper thiocyanate and additives….138Cite
Willemin ME, Lumen A.Toxicol Appl Pharmacol. 2019 Feb 15;365:84-100. doi: 10.1016/j.taap.2019.01.007. Epub 2019 Jan 9.PMID: 30639275
However, unlike perchlorate, thiocyanate presents additional modes of action within the thyroid that could contribute to the overall thyroid perturbation. …Our findings emphasize the need for more mechanistic data for chronic exposure scenarios to characterize better the …139Cite
Singh H, Mishra BK.Water Sci Technol. 2018 Dec;78(10):2214-2227. doi: 10.2166/wst.2018.503.PMID: 30629549
The present study explored the feasibility of using graphite electrodes for the electrochemical oxidation of cyanide, thiocyanate, phenol and aniline with hydrogen peroxide. The dosing effects of hydrogen peroxide and current density were examined in the pre-treated coke o …140Cite
Lafin JT, Sarsour EH, Kalen AL, Wagner BA, Buettner GR, Goswami PC.Int J Mol Sci. 2019 Jan 8;20(1):225. doi: 10.3390/ijms20010225.PMID: 30626124 Free PMC article.
Results from 4,4-difluoro-4-bora-3a,4a-diaza-S-indacene (BODIPY) C11 oxidation and ferric thiocyanate assays revealed that MSA induced LPO in cells rapidly and persistently. Propidium iodide (PI) exclusion assay found that MSA was more toxic to cancer cells than other rela …141Cite
Lactose oxidase: A novel activator of the lactoperoxidase system in milk for improved shelf life.
Lara-Aguilar S, Alcaine SD.J Dairy Sci. 2019 Mar;102(3):1933-1942. doi: 10.3168/jds.2018-15537. Epub 2019 Jan 3.PMID: 30612796 Free article.
The lactoperoxidase system (LS), an antimicrobial system naturally present in milk that is activated by H(2)O(2), has been used to inhibit microbial outgrowth in raw milk in areas where refrigeration is not viable. …Lactose oxidase oxidizes lactose and produces H(2)O(2) …142Cite
Molecular Modelling Studies of 1,4-Diaryl-2-Mercaptoimidazole Derivatives for Antimicrobial Potency.
Rani N, Singh R.Curr Comput Aided Drug Des. 2019;15(5):409-420. doi: 10.2174/1573409915666181219124956.PMID: 30569875
BACKGROUND: Imidazoles are considered as potent antimicrobial agents. In view of this 2-mercaptoimidazoles were synthesized and evaluated for antimicrobial study. METHODS: Some new 2-mercaptoimidazoles 4a-r were synthesized using substituted aniline and subst …143Cite
Huang YY, Rajda PJ, Szewczyk G, Bhayana B, Chiang LY, Sarna T, Hamblin MR.Photochem Photobiol Sci. 2019 Feb 13;18(2):505-515. doi: 10.1039/c8pp00452h.PMID: 30534721 Free PMC article.
We have recently shown that a wide range of different inorganic salts can potentiate antimicrobial photodynamic inactivation (aPDI) and TiO2-mediated antimicrobial photocatalysis. Potentiation has been shown with azide, bromide, thiocyanate, selenocyanate, an …144Cite
Harnoss JC, Elrub QMA, Jung JO, Koburger T, Assadian O, Dissemond J, Baguhl R, Papke R, Kramer A; Supported by the Working Group Antiseptics of the International Society of Chemotherapy for Infection and Cancer (ISC).Wound Repair Regen. 2019 Mar;27(2):183-189. doi: 10.1111/wrr.12689. Epub 2018 Dec 5.PMID: 30520197
Severe CAM reactions were observed after short-term application of octenidine based wound gel (0.05%) and chlorhexidine digluconate (0.5% solution), moderate reactions for octenidine (0.05%) in aqueous solution combined with dexpanthenol (1.34%) and allantoin (0.2%) or for hydrog …145Cite
Inorganic Salts and Antimicrobial Photodynamic Therapy: Mechanistic Conundrums?
Hamblin MR, Abrahamse H.Molecules. 2018 Dec 3;23(12):3190. doi: 10.3390/molecules23123190.PMID: 30514001 Free PMC article. Review.
Most of these studies have centered around antimicrobial photodynamic inactivation that kills Gram-negative and Gram-positive bacteria in suspension. …Potassium bromide is oxidized to hypobromite, but only by titanium dioxide photocatalysis (Type I). Potassium thiocya …146Cite
Charron CS, Vinyard BT, Ross SA, Seifried HE, Jeffery EH, Novotny JA.Br J Nutr. 2018 Dec;120(12):1370-1379. doi: 10.1017/S0007114518002921.PMID: 30499426 Clinical Trial.147Cite
Rashid MI, Ali A, Andleeb S.Interdiscip Sci. 2019 Dec;11(4):597-610. doi: 10.1007/s12539-018-0308-1. Epub 2018 Nov 27.PMID: 30483939
DUOX1 is involved in lactoperoxidase-mediated innate immunity at mucosal surfaces by generation of antimicrobial hypothiocyanite at the apical surface of epithelial lining. Upon detection of bacterial pathogens mainly Pseudomonas aeruginosa, DUOX1 is activated in bronchial …148Cite
Sugita C, Shin K, Wakabayashi H, Tsuhako R, Yoshida H, Watanabe W, Kurokawa M.Acta Virol. 2018;62(4):401-408. doi: 10.4149/av_2018_408.PMID: 30472870
Hypothiocyanite (OSCN-) is a natural component of human saliva and is produced by the lactoperoxidase (LPO)/thiocyanate/hydrogen peroxide (H2O2) system. OSCN- has been previously shown to exhibit antiviral activity against influenza viruses (IFV) A/H1N1/2009 and A/H1N2/200 …149Cite
Shen Y, Chu L, Zhuan R, Xiang X, Sun H, Wang J.J Environ Manage. 2019 Feb 15;232:171-178. doi: 10.1016/j.jenvman.2018.11.050. Epub 2018 Nov 22.PMID: 30472560
This paper investigated the treatment of erythromycin thiocyanate fermentation (EryTcF) residues using ionizing radiation technology for removing ARGs and antibiotics from the fermentation residues. …150Cite
Potent anti-proliferative activities of organochalcogenocyanates towards breast cancer.
Banerjee K, Padmavathi G, Bhattacherjee D, Saha S, Kunnumakkara AB, Bhabak KP.Org Biomol Chem. 2018 Nov 21;16(45):8769-8782. doi: 10.1039/c8ob01891j.PMID: 30403243
Herein we describe the synthesis of a series of organochalcogenocyanates that have one or more selenocyanate or thiocyanate units in a single molecule. The anti-proliferative activity of these organochalcogenocyanates in different breast cancer cells shows that selenocyana …151Cite
Proteogenomic Analyses of Cellular Lysates Using a Phenol-Guanidinium Thiocyanate Reagent.
Kawashima Y, Miyata J, Watanabe T, Shioya J, Arita M, Ohara O.J Proteome Res. 2019 Jan 4;18(1):301-308. doi: 10.1021/acs.jproteome.8b00609. Epub 2018 Nov 12.PMID: 30394753152Cite
Silva FRG, Matias TMS, Souza LIO, Matos-Rocha TJ, Fonseca SA, Mousinho KC, Santos AF.Braz J Biol. 2019 Jul-Sep;79(3):452-459. doi: 10.1590/1519-6984.182959. Epub 2018 Oct 29.PMID: 30379200 Free article.
The study aimed to evaluate the antimicrobial activity, antioxidant, toxicity and phytochemical screening of the Red Propolis Alagoas. Antimicrobial activity was evaluated by disk diffusion method. Determination of antioxidant activity was performed using the DPPH a …153Cite
Luz GVS, Sousa BASM, Guedes AV, Barreto CC, Brasil LM.Molecules. 2018 Oct 19;23(10):2698. doi: 10.3390/molecules23102698.PMID: 30347718 Free PMC article. Review.
The results showed that in relation to the control of microbial contamination, the current scenario is limited, with seven publications, in which the most studied additives were isothiazolinones, oxazolidines, thiocyanates, morpholines, oxaborinanes, thiocarbamates and phe …154Cite
Synergistic inhibition of anaerobic ammonium oxidation (anammox) activity by phenol and thiocyanate.
Oshiki M, Masuda Y, Yamaguchi T, Araki N.Chemosphere. 2018 Dec;213:498-506. doi: 10.1016/j.chemosphere.2018.09.055. Epub 2018 Sep 10.PMID: 30245226
Coke-oven wastewater discharged from the steel-manufacturing process is phenol and thiocyanate (SCN)-rich wastewater, which inhibits microbial activities in biological wastewater treatment processes. …155Cite
Praziquantel Resistance in the Zoonotic Cestode Dipylidium caninum.
Jesudoss Chelladurai J, Kifleyohannes T, Scott J, Brewer MT.Am J Trop Med Hyg. 2018 Nov;99(5):1201-1205. doi: 10.4269/ajtmh.18-0533.PMID: 30226153 Free PMC article.156Cite
The Pathways of the iRFP713 Unfolding Induced by Different Denaturants.
Stepanenko OV, Stepanenko OV, Kuznetsova IM, Turoverov KK.Int J Mol Sci. 2018 Sep 15;19(9):2776. doi: 10.3390/ijms19092776.PMID: 30223568 Free PMC article.
In this work, we show that the steady-state and kinetic dependencies of the various spectral characteristics of iRFP713, developed from the bacterial phytochrome RpBphP2 and recorded at protein unfolding induced by guanidine hydrochloride (GdnHCl), guanidine thiocyanate (G …157Cite
Tunney MM, Payne JE, McGrath SJ, Einarsson GG, Ingram RJ, Gilpin DF, Juarez-Perez V, Elborn JS.J Antimicrob Chemother. 2018 Dec 1;73(12):3391-3397. doi: 10.1093/jac/dky357.PMID: 30219825
METHODS: The antimicrobial activity of ALX-009 against clinical respiratory P. aeruginosa isolates was determined by time-kill assay. …CONCLUSIONS: ALX-009 demonstrates promise as a novel antimicrobial that could be used to decrease P. aeruginosa density in the lu …158Cite
Effects of orally administered lactoferrin and lactoperoxidase on symptoms of the common cold.
Shin K, Wakabayashi H, Sugita C, Yoshida H, Sato K, Sonoda T, Yamauchi K, Abe F, Kurokawa M.Int J Health Sci (Qassim). 2018 Sep-Oct;12(5):44-50.PMID: 30202407 Free PMC article.
In saliva, LPO catalyzes the hydrogen peroxide-dependent oxidation of thiocyanate to hypothiocyanite that exhibits antimicrobial and antiviral properties. A randomized, open-label, parallel-group clinical trial was conducted to examine the effectiveness of sucking t …159Cite
Zhang L, Fang C, Liu L, Liu X, Fan S, Li J, Zhao Y, Ni S, Liu S, Wu Y.Environ Int. 2018 Nov;120:388-393. doi: 10.1016/j.envint.2018.08.024. Epub 2018 Aug 17.PMID: 30125856
OBJECTIVES: The association between exposure to iodine, perchlorate, and thiocyanate and papillary thyroid cancer (PTC) incidence was evaluated and risk factors were predicted. …RESULTS: After adjusting for confounders and creatinine standardization, urinary concentratio …160Cite
Ex vivo decontamination of yeast-colonized dentures by iodine-thiocyanate complexes.
Sebaa S, Faltot M, De Breucker S, Boucherit-Otmani Z, Bafort F, Perraudin JP, Courtois P.Clin Cosmet Investig Dent. 2018 Jul 25;10:149-158. doi: 10.2147/CCIDE.S165377. eCollection 2018.PMID: 30100762 Free PMC article.
INTRODUCTION: Under well-defined experimental conditions, and in the presence of hydrogen peroxide, lactoperoxidase produces stable iodine-thiocyanate complexes that have antimicrobial properties. A novel process was developed to short circuit the consumption of hyd …161Cite
Kühn C, Kupke F, Baldermann S, Klopsch R, Lamy E, Hornemann S, Pfeiffer AFH, Schreiner M, Hanschen FS, Rohn S.Mol Nutr Food Res. 2018 Oct;62(20):e1800588. doi: 10.1002/mnfr.201800588. Epub 2018 Aug 28.PMID: 30091516162Cite
Structural Mapping of Anion Inhibitors to β-Carbonic Anhydrase psCA3 from Pseudomonas aeruginosa.
Murray AB, Aggarwal M, Pinard M, Vullo D, Patrauchan M, Supuran CT, McKenna R.ChemMedChem. 2018 Oct 8;13(19):2024-2029. doi: 10.1002/cmdc.201800375. Epub 2018 Sep 13.PMID: 30088334
The bacterium exhibits intrinsic resistance to most antibacterial agents, including aminoglycosides and quinolones. Hence, the identification of new drug targets for P. aeruginosa is ongoing. PsCA3 is a beta-class carbonic anhydrase (beta-CA) that catalyzes the reversible …163Cite
Patel U, Gingerich A, Widman L, Sarr D, Tripp RA, Rada B.PLoS One. 2018 Jul 25;13(7):e0199167. doi: 10.1371/journal.pone.0199167. eCollection 2018.PMID: 30044776 Free PMC article.
Inactivation of different influenza virus strains was measured in vitro system containing LPO, its substrates, thiocyanate (SCN-) or iodide (I-), and the hydrogen peroxide (H2O2)-producing system, glucose and glucose oxidase (GO). …Inactivation of H1N1 and H1N2 viruses b …164Cite
Fe-T1 Sensor Based on Coordination Chemistry for Sensitive and Versatile Bioanalysis.
Dong M, Zheng W, Chen Y, Xianyu Y, Ran B, Qian Z, Jiang X.Anal Chem. 2018 Aug 7;90(15):9148-9155. doi: 10.1021/acs.analchem.8b01577. Epub 2018 Jul 24.PMID: 30016870
In this study, we observe the amplification of longitudinal relaxation time (T(1)) signal when Fe(2+) transforms into Fe(3+) followed by the coordination of potassium thiocyanate (KSCN) and develop a sensitive Fe-T(1) sensor based on the coordination chemistry between KSCN …165Cite
[Aerobic Degradation and Microbial Community Succession of Coking Wastewater with Municipal Sludge].
Liu GX, Wu HZ, Sun SL, Hu XY, Wu XY, Chen HY, Fan YW, Hu CS, Wei CH.Huan Jing Ke Xue. 2017 Sep 8;38(9):3807-3815. doi: 10.13227/j.hjkx.201702146.PMID: 29965263 Chinese.
In the stage of phenol degradation, the abundance of Acinetobacter and Pseudomonas increased rapidly; the species richness was 13.04% of the community at 48 h. In the stage of thiocyanate degradation, Sphingobacterium,Brevundimonas,Lysobacter, and Chryseobacterium were the …166Cite
Nguyen TT, Suzuki S, Sugamata R, Ito F, Tran DH, Yamamoto T, Kawachi S, Suzuki K.Tohoku J Exp Med. 2018 Jun;245(2):131-140. doi: 10.1620/tjem.245.131.PMID: 29962372 Free article.
Recent studies have demonstrated the virucidal activity of hypothiocyanous acid (HOSCN), an oxidant generated by the peroxidase-catalyzed reaction of thiocyanate with hydrogen peroxide. However, the effects of HOSCN on host antiviral responses are still unknown. …167Cite
Comparison of thiocyanate and selenocyanate for potentiation of antimicrobial photodynamic therapy.
Huang L, Xuan W, Sarna T, Hamblin MR.J Biophotonics. 2019 Jan;12(1):e201800092. doi: 10.1002/jbio.201800092. Epub 2018 Aug 3.PMID: 29885019 Free PMC article.
We have previously shown that antimicrobial photodynamic therapy (aPDT) mediated by different photosensitizers (PS) can be potentiated by a variety of inorganic salts. Potassium thiocyanate (KSCN) potentiated aPDT mediated by methylene blue (MB), while potassium sel …168Cite
Antimicrobial actions of dual oxidases and lactoperoxidase.
Sarr D, Tóth E, Gingerich A, Rada B.J Microbiol. 2018 Jun;56(6):373-386. doi: 10.1007/s12275-018-7545-1. Epub 2018 Jun 1.PMID: 29858825 Free PMC article. Review.
DUOX enzymes highly expressed in the respiratory and salivary gland epithelium have been proposed as the major sources of hydrogen peroxide supporting mucosal oxidative antimicrobial defenses. In this review, we shortly present data on DUOX discovery, structure and functio …169Cite
Bader M, Dunkel A, Wenning M, Kohler B, Medard G, Del Castillo E, Gholami A, Kuster B, Scherer S, Hofmann T.J Agric Food Chem. 2018 Jun 6;66(22):5621-5634. doi: 10.1021/acs.jafc.8b02092. Epub 2018 May 29.PMID: 29787679
Gene ontology enrichment analysis showed evidence for stimulus-induced alterations of the saliva proteome to boot an efficient molecular defense network of the oral cavity, e.g., 6-gingerol increased salivary lactoperoxidase activity, catalyzing the oxidation of thiocyanate …170Cite
Tomar SK, Chakraborty S.J Environ Manage. 2018 Aug 1;219:178-188. doi: 10.1016/j.jenvman.2018.04.111. Epub 2018 May 5.PMID: 29738935
The impact of air flow rate on aerobic granulation was evaluated for treating toxic multiple pollutants; phenol (400 mg L(-1)), thiocyanate (100 mg L(-1)) and ammonia nitrogen (100 mg L(-1)) by using three lab scale sequencing batch reactors (SBRs) (R1, R2 and R3). …171Cite
Bhattacharya U, Chandra AK.J Trop Pediatr. 2019 Feb 1;65(1):55-62. doi: 10.1093/tropej/fmy011.PMID: 29660100
To evaluate the state of iodine nutrition in post-iodation scenario, 3500 children were examined clinically for endemic goitre. Iodine and thiocyanate were measured in 240 urine samples; iodine content in 210 salt samples was measured. …Median urinary iodine level was 21 …172Cite
Bathish B, Turner R, Paumann-Page M, Kettle AJ, Winterbourn CC.Arch Biochem Biophys. 2018 May 15;646:120-127. doi: 10.1016/j.abb.2018.03.038. Epub 2018 Apr 4.PMID: 29626421
This implies selectivity for the enzymatic process. Physiological concentrations of thiocyanate and urate partially inhibited cross-link formation. 4-Aminobenzoic acid hydrazide, a commonly used myeloperoxidase inhibitor, also inhibited peroxidasin, whereas acetaminophen a …173Cite
In vitro comparative cytotoxicity study of a novel biocidal iodo-thiocyanate complex.
Tonoyan L, Boyd A, Fleming GTA, Friel R, Gately CM, Mc Cay PH, O’Flaherty V.Toxicol In Vitro. 2018 Aug;50:264-273. doi: 10.1016/j.tiv.2018.03.014. Epub 2018 Apr 3.PMID: 29621560
Here, we compared the cytotoxic and bactericidal effects of a new antimicrobial agent, the iodo-thiocyanate complex (ITC), with those of the common antiseptics, hydrogen peroxide (H(2)O(2)), povidone iodine (PVP-I) and Lugol’s iodine (Lugol). The antimicrobials …174Cite
Specific and robust ion chromatographic determination of hypothiocyanite in saliva samples.
Below H, Baguhl R, Geßner W, Kramer A, Below E, Kahlert H, Welk A.Anal Bioanal Chem. 2018 Apr;410(11):2739-2749. doi: 10.1007/s00216-018-0954-5. Epub 2018 Mar 5.PMID: 29508035
The enzymatic system in saliva, consisting of salivary peroxidase (SPO), hydrogen peroxide (H(2)O(2)), and thiocyanate (SCN(-)), produces hypothiocyanite (OSCN(-)) as a high effective antibacterial compound. …175Cite
Huang L, Xuan W, Zadlo A, Kozinska A, Sarna T, Hamblin MR.J Biophotonics. 2018 Aug;11(8):e201800029. doi: 10.1002/jbio.201800029. Epub 2018 May 6.PMID: 29488327 Free PMC article.
We previously showed that antimicrobial photodynamic inactivation (aPDI) of Gram-positive and Gram-negative bacteria mediated by the phenothiazinium dye, methylene blue (MB), was potentiated by the addition of potassium thiocyanate (10 mM). …176Cite
Pulsed corona discharge for improving treatability of coking wastewater.
Liu M, Preis S, Kornev I, Hu Y, Wei CH.J Environ Sci (China). 2018 Feb;64:306-316. doi: 10.1016/j.jes.2017.07.003. Epub 2017 Jul 12.PMID: 29478652
The energy efficiency of COD, phenol, thiocyanate and cyanide degradation by PCD was the subject of the research. The cost-effective removal of intermediate oxidation products with addition of lime was also studied. …Oxidative treatment of RCW showed the removal of pheno …177Cite
Atas M, Eruygur N, Ucar E, Ozyigit Y, Turgut K.Cell Mol Biol (Noisy-le-grand). 2018 Feb 10;64(2):39-45. doi: 10.14715/cmb/2018.64.2.8.PMID: 29433627
The components in methanol extracts of plants were determined by gas chromatography-mass spectrometry (GC-MS) method. Antimicrobial activities of stevia extracts were investigated by microdilution method. The antioxidant activity evaluated by 2, 2-diphenyl-1-picrylhydrazyl …178Cite
Izuhara K, Suzuki S, Ogawa M, Nunomura S, Nanri Y, Mitamura Y, Yoshihara T.Oxid Med Cell Longev. 2017;2017:1054801. doi: 10.1155/2017/1054801. Epub 2017 Nov 22.PMID: 29359006 Free PMC article. Review.
Heme peroxidase inhibitors, widely used as antithyroid agents, diminish asthma-like phenotypes in mice, indicating the significance of this pathway. These findings suggest the possibility of repositioning antithyroid agents as antiasthma drugs….179Cite
Kyzioł A , Cierniak A , Gubernator J , Markowski A , Jeżowska-Bojczuk M , Komarnicka UK .Dalton Trans. 2018 Feb 6;47(6):1981-1992. doi: 10.1039/c7dt03917d.PMID: 29345262
The cytotoxic effect of iodide or thiocyanate copper(i) complexes (1-PSf, 2-PSf, 3-PSf, 4-PSf) with phosphine derived from sparfloxacin (HSf) and 2,9-dimethyl-1,10-phenanthroline (dmp) or 2,2′-biquinoline (bq) as diimine auxiliary ligands was proved in vitro on somatic (MR …180Cite
Zhu LP, Wang JP, Ding XM, Bai SP, Zeng QF, Su ZW, Xuan Y, Zhang KY.J Agric Food Chem. 2018 Feb 14;66(6):1560-1568. doi: 10.1021/acs.jafc.7b05782. Epub 2018 Jan 30.PMID: 29345135
This study was to investigate the deposition and elimination of glucosinolate metabolites including 5-vinyl-1,3-oxazolidine-2-thione (5-VOT) and thiocyanate ion (SCN(-)) derived from rapeseed meal (RSM) in hen eggs. During 12 weeks accumulation phase, the serum triiodothyr …181Cite
Barbosa MCS, de Souza Barbosa C, de Oliveira JT, Moreira NCS, de Miranda Martins NR, Alves Gomes GK, Caldeira CA, Alves E Costa ML, Martins Guimarães DS, Guimarães L, Nascimento CS Jr, de Pilla Varotti F, Ribeiro Viana GH, Santos FVD.Mutat Res Genet Toxicol Environ Mutagen. 2018 Jan;825:31-39. doi: 10.1016/j.mrgentox.2017.11.006. Epub 2017 Nov 24.PMID: 29307373
In the present work, two new 3-APAs analogues were synthesized based on molecular modeling studies to act as potential antimalarial agents. These theoneladin C analogues, containing the thiocyanate group in their chemical structures, were synthesized and evaluated a …182Cite
Rigoni A, Poulsom R, Jeffery R, Mehta S, Lewis A, Yau C, Giannoulatou E, Feakins R, Lindsay JO, Colombo MP, Silver A.Inflamm Bowel Dis. 2017 Dec 19;24(1):136-148. doi: 10.1093/ibd/izx024.PMID: 29272487
Inflammation, hypoxia, and 5-aminosalicylic acid increase H2O2 production, supporting innate defense and mucosal healing. Thiocyanate reacts with H2O2 in the presence of lactoperoxidase (LPO) to form hypothiocyanate (OSCN-), which acts as a biocide and H2O2 scavenging syst …183Cite
Bafort F, Damblon C, Smargiasso N, De Pauw E, Perraudin JP, Jijakli MH.Chem Biodivers. 2018 Mar;15(3):e1700497. doi: 10.1002/cbdv.201700497. Epub 2018 Mar 7.PMID: 29266741184Cite
Nicolussi A, Dunn JD, Mlynek G, Bellei M, Zamocky M, Battistuzzi G, Djinović-Carugo K, Furtmüller PG, Soldati T, Obinger C.J Biol Chem. 2018 Jan 26;293(4):1330-1345. doi: 10.1074/jbc.RA117.000463. Epub 2017 Dec 14.PMID: 29242189 Free PMC article.
Oxidation of halides and thiocyanate by heme peroxidases to antimicrobial oxidants is an important cornerstone in the innate immune system of mammals. …The metalloprotein follows the halogenation cycle, whereby compound I oxidizes iodide and thiocyanate at …185Cite
Urinary Iodine, Perchlorate, and Thiocyanate Concentrations in U.S. Lactating Women.
Lee SY, McCarthy AM, Stohl H, Ibrahim S, Jeong C, Braverman LE, Ma W, He X, Mestman JH, Schuller KE, Jahreis KA, Pearce EN, Leung AM.Thyroid. 2017 Dec;27(12):1574-1581. doi: 10.1089/thy.2017.0158.PMID: 29130403 Free PMC article.
To adequately assess the iodine sufficiency of lactating women and potential associations with environmental perchlorate and thiocyanate exposure, we conducted a multicenter, cross-sectional study of urinary iodine, perchlorate, and thiocyanate concentrations in hea …186Cite
Chao MN, Storey M, Li C, Rodríguez MG, Di Salvo F, Szajnman SH, Moreno SNJ, Docampo R, Rodriguez JB.Bioorg Med Chem. 2017 Dec 15;25(24):6435-6449. doi: 10.1016/j.bmc.2017.10.016. Epub 2017 Oct 16.PMID: 29107437
In the present study we designed, synthesized and evaluated the effect of a number of isosteric analogues of WC-9 (4-phenoxyphenoxyethyl thiocyanate), a known squalene synthase inhibitor, on T. cruzi growth in tissue culture cells. …The results indicate that compounds be …187Cite
Potentiation of antimicrobial photodynamic inactivation by inorganic salts.
Hamblin MR.Expert Rev Anti Infect Ther. 2017 Nov;15(11):1059-1069. doi: 10.1080/14787210.2017.1397512. Epub 2017 Oct 31.PMID: 29084463 Free PMC article. Review.
Antimicrobial photodynamic inactivation (aPDI) involves the use of non-toxic dyes excited with visible light to produce reactive oxygen species (ROS) that can destroy all classes of microorganisms including bacteria, fungi, parasites, and viruses. Selectivity of killing mi …188Cite
Reactivation of peroxidase activity in human saliva samples by polyphenols.
Gau J, Arnhold J, Flemmig J.Arch Oral Biol. 2018 Jan;85:70-78. doi: 10.1016/j.archoralbio.2017.09.037. Epub 2017 Oct 7.PMID: 29032047
OBJECTIVES: The enzyme lactoperoxidase (LPO), which is released into several body fluids like saliva, is an essential part to maintain the oral bacterial homeostasis by catalysing the oxidation of thiocyanate (SCN(-)) to hypo-thiocyanite ((-)OSCN). The formation of unreact …189Cite
Khan SA, Noreen F, Kanwal S, Iqbal A, Hussain G.Mater Sci Eng C Mater Biol Appl. 2018 Jan 1;82:46-59. doi: 10.1016/j.msec.2017.08.071. Epub 2017 Aug 17.PMID: 29025674
The antibacterial and antifungal activities of M1 and M2 NAPs were determined by agar diffusion method, while their antioxidant properties were assessed through DPPH radical scavenging and ferric thiocyanate (FTC) and assays. Under sunlight irradiation, photocatalytic disi …190Cite
Effect of heat shock protein 90 against ROS-induced phospholipid oxidation.
Zhang M, Wang D, Geng Z, Li P, Sun Z, Xu W.Food Chem. 2018 Feb 1;240:642-647. doi: 10.1016/j.foodchem.2017.08.005. Epub 2017 Aug 2.PMID: 28946323
Lipid oxidation was assessed by ferric thiocyanate method, and particle size, zeta potential measurements and transmission electron microscopy were employed to detect physical and chemical changes during oxidation of liposomes. …191Cite
A fluorescence method for determination of glucose transport by intestinal BBMV of common carp.
Yang LP, Yan X, Zheng WJ, Hu JY, Zhang YR, Qin CB, Meng XL, Lu RH, Chen F, Xie DZ, Nie GX.Anal Biochem. 2017 Nov 15;537:20-25. doi: 10.1016/j.ab.2017.08.015. Epub 2017 Aug 26.PMID: 28847591192Cite
Setz C, Friedrich M, Rauch P, Fraedrich K, Matthaei A, Traxdorf M, Schubert U.Viruses. 2017 Aug 12;9(8):222. doi: 10.3390/v9080222.PMID: 28805676 Free PMC article.193Cite
Eom SJ, Hwang JE, Jung J, Jee HS, Kim KT, Paik HD.J Dairy Sci. 2017 Oct;100(10):7788-7792. doi: 10.3168/jds.2017-12725. Epub 2017 Aug 10.PMID: 28803022 Free article.
Higher antioxidative activity of fermented ginseng marc extract was obtained in the beta-carotene bleaching, ferric-reducing ability of plasma, and ferric thiocyanate assays than the 1,1-diphenyl-2-picrylhydrazy assay. However, the 1,1-diphenyl-2-picrylhydrazy scavenging e …194Cite
Pseudomonas aeruginosa defense systems against microbicidal oxidants.
Groitl B, Dahl JU, Schroeder JW, Jakob U.Mol Microbiol. 2017 Nov;106(3):335-350. doi: 10.1111/mmi.13768. Epub 2017 Aug 29.PMID: 28795780 Free PMC article.
The most abundant oxidants controlling bacterial colonization on mucosal barrier epithelia are hypochlorous acid (HOCl), hypobromous acid (HOBr) and hypothiocyanous acid (HOSCN). All three oxidants are highly antimicrobial but little is known about their relative efficacie …195Cite
Regenerative biosensor for use with biotinylated bait molecules.
Knoglinger C, Zich A, Traxler L, Poslední K, Friedl G, Ruttmann B, Schorpp A, Müller K, Zimmermann M, Gruber HJ.Biosens Bioelectron. 2018 Jan 15;99:684-690. doi: 10.1016/j.bios.2017.07.033. Epub 2017 Jul 13.PMID: 28734694 Free article.
When desired, however, streptavidin plus the biotinylated bait can be completely removed by 3min injections of biotin, guanidinium thiocyanate, pepsin, and SDS, which makes it possible to immobilize new biotinylated bait. …196Cite
Kim SSR, He X, Braverman LE, Narla R, Gupta PK, Leung AM.Endocr Pract. 2017 Jul;23(7):885-886. doi: 10.4158/1934-2403-23.7.885.PMID: 28703651 Free PMC article. No abstract available.197Cite
Sahariah BP, Anandkumar J, Chakraborty S.Environ Technol. 2018 Aug;39(15):1898-1907. doi: 10.1080/09593330.2017.1343388. Epub 2017 Jun 26.PMID: 28617189
The stability of two sequential moving bed bioreactor systems operated in anaerobic-anoxic-aerobic continuous moving bed bioreactor (CMBR: R1-R2-R3) and semi-continuous fed batch moving bed bioreactor (FMBR: B1-B2-B3) modes was assessed for phenol shock load (PSL) applications in …198Cite
Joshi VS, Kreth J, Koley D.Anal Chem. 2017 Jul 18;89(14):7709-7718. doi: 10.1021/acs.analchem.7b01677. Epub 2017 Jun 28.PMID: 28613833 Free PMC article.
We were also able to detect 30 muM H(2)O(2) at 50 mum above the biofilm in the presence of the H(2)O(2)-decomposing salivary lactoperoxidase and thiocyanate, which would not otherwise be possible using an existing H(2)O(2) assay. Thus, this sensor can potentially find appl …199Cite
Sahariah BP, Anandkumar J, Chakraborty S.Environ Technol. 2018 Jul;39(14):1786-1794. doi: 10.1080/09593330.2017.1340344. Epub 2017 Jun 26.PMID: 28592192
Pyridine degradation in B1, B2 and B3 follows the Stover-Kincannon model with a maximum substrate removal rate of 111.1, 333.3 and 23.81 g/L day, respectively. Thiocyanate removal in B2 and ammonia removal in B3 follows the Bhatia inhibition model with a maximum substrate …200Cite
Antibacterial Potential of an Antimicrobial Agent Inspired by Peroxidase-Catalyzed Systems.
Tonoyan L, Fleming GTA, Mc Cay PH, Friel R, O’Flaherty V.Front Microbiol. 2017 May 2;8:680. doi: 10.3389/fmicb.2017.00680. eCollection 2017.PMID: 28512449 Free PMC article.
We report the synthesis of a biocidal complex, which is produced by the reaction between ionic oxidizable salts-iodide and thiocyanate-in the presence of hydrogen peroxide as an oxidation source. The reaction generates bactericidal reactive oxygen and iodine species. In th …
Suicide attempt with acetonitrile ingestion in a nursing mother.
De Capitani EM, Borrasca-Fernandes CF, Branco Pimenta M, Prado CC, Soubhia PC, Lanaro R, Mello Moreira S, Linden R, Nóbrega HV, Bucaretchi F, Costa JL.Clin Toxicol (Phila). 2017 Sep;55(8):929-933. doi: 10.1080/15563650.2017.1324977. Epub 2017 May 11.PMID: 28494173
Blood and urine samples were collected 24 h later for ACN, CN and thiocyanate analysis, and 12.5 g sodium thiosulfate i.v. in 1-h infusion was started and repeated every 24 h for 4 days. …202Cite
Guo Q, Shi ZJ, Yang CC, Huang M, Xu JL, Xu YQ, Ni WM, Jin RC.Environ Sci Pollut Res Int. 2017 Jun;24(16):14207-14217. doi: 10.1007/s11356-017-9024-3. Epub 2017 Apr 18.PMID: 28421522
This study evaluated the individual and interactive effect of phenol and thiocyanate (SCN(-)) on partial nitritation (PN) activity using batch test and response surface methodology. …203Cite
Datta D, J Swamy M.J Photochem Photobiol B. 2017 May;170:108-117. doi: 10.1016/j.jphotobiol.2017.03.026. Epub 2017 Apr 1.PMID: 28414980
The fluorescence emission maximum of native MLGL seen at 326nm shifts to 350nm upon incubation with 6M guanidinium thiocyanate (Gdn.SCN), suggesting that the tryptophans are located inside the hydrophobic core of the protein and become fully exposed upon denaturation. …204Cite
Westphal AH, Geerke-Volmer AA, van Mierlo CPM, van Berkel WJH.Biotechnol J. 2017 Jun;12(6). doi: 10.1002/biot.201700007. Epub 2017 May 15.PMID: 28403549205Cite
Gau J, Prévost M, Van Antwerpen P, Sarosi MB, Rodewald S, Arnhold J, Flemmig J.J Nat Prod. 2017 May 26;80(5):1328-1338. doi: 10.1021/acs.jnatprod.6b00915. Epub 2017 Apr 3.PMID: 28368593206Cite
Corey LM, Bell GP, Pleus RC.Bull Environ Contam Toxicol. 2017 Jul;99(1):83-88. doi: 10.1007/s00128-017-2077-7. Epub 2017 Apr 1.PMID: 28365805
Perchlorate, thiocyanate, nitrate, and iodide all have the same action of iodide uptake inhibition. Urinary samples were available for the US population through the National Health and Nutrition Examination Survey (NHANES) database for these compounds and were evaluated fo …207Cite
The antimicrobial volatile power of the rhizospheric isolate Pseudomonas donghuensis P482.
Ossowicki A, Jafra S, Garbeva P.PLoS One. 2017 Mar 30;12(3):e0174362. doi: 10.1371/journal.pone.0174362. eCollection 2017.PMID: 28358818 Free PMC article.
The production of certain volatiles such as dimethyl sulfide, S-methyl thioacetate, methyl thiocyanate, dimethyl trisulfide, 1-undecan and HCN is depended on the GacS/GacA two-component regulatory system. …208Cite
Re: “Iodine Content in Milk Alternatives” by Ma et al. (Thyroid 2016;26:1308-1310).
Vance K, Makhmudov A, Jones RL, Caldwell KL.Thyroid. 2017 May;27(5):748-749. doi: 10.1089/thy.2017.0056. Epub 2017 Apr 14.PMID: 28292219 Free PMC article. No abstract available.209Cite
USP7 deubiquitinase controls HIV-1 production by stabilizing Tat protein.
Ali A, Raja R, Farooqui SR, Ahmad S, Banerjea AC.Biochem J. 2017 May 4;474(10):1653-1668. doi: 10.1042/BCJ20160304.PMID: 28280111210Cite
Paumann-Page M, Katz RS, Bellei M, Schwartz I, Edenhofer E, Sevcnikar B, Soudi M, Hofbauer S, Battistuzzi G, Furtmüller PG, Obinger C.J Biol Chem. 2017 Mar 17;292(11):4583-4592. doi: 10.1074/jbc.M117.775213. Epub 2017 Jan 31.PMID: 28154175 Free PMC article.
We demonstrate that chloride cannot act as a two-electron donor of compound I, whereas thiocyanate, iodide, and bromide efficiently restore the ferric resting state. We present all relevant apparent bimolecular rate constants, the spectral signatures of the redox intermedi …211Cite
Effect of Salt and Ethanol Addition on Zein-Starch Dough and Bread Quality.
Smith BM, Bean SR, Selling G, Sessa D, Aramouni FM.J Food Sci. 2017 Mar;82(3):613-621. doi: 10.1111/1750-3841.13637. Epub 2017 Feb 2.PMID: 28152197212Cite
Kang M, Park H, Jun JH, Son M, Kang MJ.Drug Des Devel Ther. 2017 Jan 11;11:185-191. doi: 10.2147/DDDT.S121254. eCollection 2017.PMID: 28138222 Free PMC article.
In this study, a novel artificial saliva containing inorganic salts, including sodium chloride and potassium chloride, and bactericidal agents, including potassium thiocyanate and lactoperoxidase, was formulated in the form of a solution (DM-sol) or gel (DM-gel). .. …213Cite
The effect of smoking on placental pendrin expression.
Karatas A, Erdem H, Karatas Z, Ozlu T, Cakmak B.J Obstet Gynaecol. 2017 Jan;37(1):11-14. doi: 10.1080/01443615.2016.1174825. Epub 2016 Dec 25.PMID: 28013561
Pendrin is important for transport of iodine across the placenta. Thiocyanate coming from cigarette is a competitive inhibitor of iodine transport. We aimed to evaluate the pendrin immunostaining intensity in placentas of smoker and non-smoker women. …214Cite
Ismael FO, Barrett TJ, Sheipouri D, Brown BE, Davies MJ, Hawkins CL.PLoS One. 2016 Dec 20;11(12):e0168844. doi: 10.1371/journal.pone.0168844. eCollection 2016.PMID: 27997605 Free PMC article.215Cite
Correlation of lysozyme activity and stability in the presence of Hofmeister series anions.
Garajová K, Balogová A, Dušeková E, Sedláková D, Sedlák E, Varhač R.Biochim Biophys Acta Proteins Proteom. 2017 Mar;1865(3):281-288. doi: 10.1016/j.bbapap.2016.11.016. Epub 2016 Nov 30.PMID: 27915090
The effect of sodium salts of sulfate, acetate, chloride, bromide, thiocyanate, and perchlorate on lysozyme properties depends on anion concentration as well as on position of anion in the Hofmeister series. Kosmotropic anions (sulfate and acetate) increase stability and a …216Cite
Del Prete S, Vullo D, Di Fonzo P, Osman SM, AlOthman Z, Supuran CT, Capasso C.Bioorg Med Chem. 2017 Jan 15;25(2):575-580. doi: 10.1016/j.bmc.2016.11.021. Epub 2016 Nov 14.PMID: 27914949
The best BpsgammaCA inhibitors were sulfamide, sulfamic acid, phenylboronic acid and phenylarsonic acid, which showed K(I) in the range of 49-83muM (these inhibitors showed millimolar inhibition constant against hCA II), followed by diethyldithiocarbamate, selenate, tellurate, pe …217Cite
Chao MN, Li C, Storey M, Falcone BN, Szajnman SH, Bonesi SM, Docampo R, Moreno SN, Rodriguez JB.ChemMedChem. 2016 Dec 16;11(24):2690-2702. doi: 10.1002/cmdc.201600505. Epub 2016 Nov 25.PMID: 27886451 Free PMC article.
In this work, a number of compounds structurally related to WC-9 (4-phenoxyphenoxyethyl thiocyanate), a known squalene synthase inhibitor, were designed, synthesized, and evaluated for their effect on T. cruzi and T. gondii growth in tissue culture cells. Two fluorine-cont …218Cite
Induction of Airway Allergic Inflammation by Hypothiocyanite via Epithelial Cells.
Suzuki S, Ogawa M, Ohta S, Nunomura S, Nanri Y, Shiraishi H, Mitamura Y, Yoshihara T, Lee JJ, Izuhara K.J Biol Chem. 2016 Dec 30;291(53):27219-27227. doi: 10.1074/jbc.M116.746909. Epub 2016 Nov 18.PMID: 27864363 Free PMC article.
OSCN(-) is generated by the catalysis of peroxidases using thiocyanate transported via several anion transporters, including pendrin/SLC26A4 and hydrogen peroxide (H(2)O(2)) generated by Duox1 and Duox2. …219Cite
von Oettingen JE, Brathwaite TD, Carpenter C, Bonnell R, He X, Braverman LE, Pearce EN, Larco P, Larco NC, Jean-Baptiste E, Brown RS.J Clin Endocrinol Metab. 2017 Feb 1;102(2):644-651. doi: 10.1210/jc.2016-2630.PMID: 27768855
MAIN OUTCOME MEASURES: Urinary iodide, serum thyrotropin (TSH), goiter assessment, and urinary perchlorate and thiocyanate. RESULTS: Mean age was 3.31.6 years, with 51% female, median family income USD 30/week, and 16% malnutrition. …Grade 1 goiters were palpated in 2 ch …220Cite
Komarnicka UK, Starosta R, Kyzioł A, Płotek M, Puchalska M, Jeżowska-Bojczuk M.J Inorg Biochem. 2016 Dec;165:25-35. doi: 10.1016/j.jinorgbio.2016.09.015. Epub 2016 Sep 30.PMID: 27764707
In this paper we present lomefloxacin’s (HLm, 2nd generation fluoroquinolone antibiotic agent) organic and inorganic derivatives: aminomethyl(diphenyl)phosphine (PLm), its oxide as well as new copper(I) iodide or copper(I) thiocyanate complexes with PLm and 2,9-dimethyl-1, …221Cite
Effect of Nitrates, Thiocyanates and Selenium on the Iron and Iodine Status of Postpartum Women.
Bivolarska AV, Maneva AI, Gatseva PD, Katsarova MN.Folia Med (Plovdiv). 2016 Sep 1;58(3):188-194. doi: 10.1515/folmed-2016-0024.PMID: 27760010
AIM: To find correlations between high thiocyanate and nitrate levels and low selenium levels and the indicators of the iodine and iron status of postpartum women. …RESULTS: Assessing the iodine status, we found a negative correlation between the levels of iodine and …222Cite
Schlorke D, Atosuo J, Flemmig J, Lilius EM, Arnhold J.Free Radic Res. 2016 Dec;50(12):1287-1295. doi: 10.1080/10715762.2016.1235789. Epub 2016 Oct 12.PMID: 27629563
In the presence of hydrogen peroxide, the heme protein lactoperoxidase is able to oxidize thiocyanate and iodide to hypothiocyanite, reactive iodine species, and the inter(pseudo)halogen cyanogen iodide. …223Cite
Guzmán-Pérez V, Bumke-Vogt C, Schreiner M, Mewis I, Borchert A, Pfeiffer AF.PLoS One. 2016 Sep 13;11(9):e0162397. doi: 10.1371/journal.pone.0162397. eCollection 2016.PMID: 27622707 Free PMC article.224Cite
Eosinophil Peroxidase Catalyzed Protein Carbamylation Participates in Asthma.
Wang Z, DiDonato JA, Buffa J, Comhair SA, Aronica MA, Dweik RA, Lee NA, Lee JJ, Thomassen MJ, Kavuru M, Erzurum SC, Hazen SL.J Biol Chem. 2016 Oct 14;291(42):22118-22135. doi: 10.1074/jbc.M116.750034. Epub 2016 Sep 1.PMID: 27587397 Free PMC article.
Using a combination of studies we now show EPO uses plasma levels of the pseudohalide thiocyanate (SCN(-)) as substrate to catalyze protein carbamylation, as monitored by PTM of protein lysine residues into N()-carbamyllysine (homocitrulline), and contributes to the pathop …225Cite
Mölder T, Speek M.Biotechniques. 2016 Aug 1;61(2):61-5. doi: 10.2144/000114441. eCollection 2016.PMID: 27528070 Free article.226Cite
Thiocyanate Accumulation in Critically Ill Patients Receiving Nitroprusside Infusions.
Morris AA, Page RL 2nd, Baumgartner LJ, Mueller SW, MacLaren R, Fish DN, Kiser TH.J Intensive Care Med. 2017 Oct;32(9):547-553. doi: 10.1177/0885066616657004. Epub 2016 Jul 19.PMID: 27435907
PURPOSE: This study evaluated thiocyanate concentrations and factors associated with thiocyanate accumulation in intensive care unit patients receiving nitroprusside with and without sodium thiosulfate coadministration. …Despite elevated thiocyanate levels …227Cite
New insights into thiocyanate oxidation by human myeloperoxidase.
Schlorke D, Flemmig J, Gau J, Furtmüller PG, Obinger C, Arnhold J.J Inorg Biochem. 2016 Sep;162:117-126. doi: 10.1016/j.jinorgbio.2016.06.019. Epub 2016 Jun 15.PMID: 27343172
Human myeloperoxidase (MPO) uses chloride and thiocyanate as physiological substrates at neutral pH. Oxidation of thiocyanate to hypothiocyanite mediated by the redox intermediate Compound I rapidly restores the ferric state of MPO. At low thiocyanate concent …228Cite
Nishimoto Y, Mizutani S, Nakajima T, Hosoda F, Watanabe H, Saito Y, Shibata T, Yachida S, Yamada T.Gut. 2016 Sep;65(9):1574-5. doi: 10.1136/gutjnl-2016-311937. Epub 2016 Jun 23.PMID: 27340192 Free PMC article. No abstract available.229Cite
WC-9 a Lead Drug with Great Prospects for American Trypanosomiasis and Toxoplasmosis.
Rodriguez JB.Mini Rev Med Chem. 2016;16(15):1195-1200. doi: 10.2174/1389557516666160611015034.PMID: 27290911 Review.
In fact, some effective ergosterol biosynthesis inhibitors bearing suitable pharmacokinetic properties in mammals have become putative antiparasitic agents by inducing almost complete parasitological cure in both acute and chronic experimental Chagas disease. WC-9 (compoun …230Cite
Effect of various storage conditions on the stability of quinolones in raw milk.
Chen M, Wen F, Wang H, Zheng N, Wang J.Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2016 Jul;33(7):1147-54. doi: 10.1080/19440049.2016.1184051. Epub 2016 Jun 9.PMID: 27258809
The storage conditions included different temperatures and durations (4C for 4, 8, 24 and 48 h; -20C for 1, 7 and 30 days; -80C for 1, 7 and 30 days), thawing temperatures (25, 40 and 60C), freeze-thaw cycles (1-5), and the addition of different preservatives (sodium thiocyana …231Cite
Eisenbrand G, Gelbke HP.Arch Toxicol. 2016 Aug;90(8):1841-57. doi: 10.1007/s00204-016-1735-6. Epub 2016 May 11.PMID: 27169853 Review.
Occurrence and mode of action of potentially relevant goitrogens in human nutrition and their mode of action (MOA) are reviewed, with special focus on the anionic iodine uptake inhibitors perchlorate (PER), thiocyanate (SCN) and nitrate (NO3). Epidemiological studies sugge …232Cite
Azab ME, Rizk SA, Mahmoud NF.Chem Pharm Bull (Tokyo). 2016;64(5):439-50. doi: 10.1248/cpb.c15-01005.PMID: 27150476 Free article.
Treatment of the hydrazide 12 with aromatic aldehydes, acetic anhydride, ethyl acetoacetate, acetyl acetone, ammonium thiocyanate, and/or phthalic anhydride furnished compounds 17-21. Meanwhile, reacting Schiff base 22 with the chlorophthalazine derivative 9 produced compo …233Cite
Xu J, Meng J, Meng X, Zhao Y, Liu J, Sun T, Liu Y, Wang Q, Zhang S.Plant Cell. 2016 May;28(5):1144-62. doi: 10.1105/tpc.15.00871. Epub 2016 Apr 14.PMID: 27081184 Free PMC article.
Antimicrobial compounds have critical roles in plant immunity; for example, Arabidopsis thaliana and other crucifers deploy phytoalexins and glucosinolate derivatives in defense against pathogens. …Under the action of PENETRATION2 (PEN2), an atypical myrosinase, and PEN3 …234Cite
Nitrite and nitroso compounds can serve as specific catalase inhibitors.
Titov VY, Osipov AN.Redox Rep. 2017 Mar;22(2):91-97. doi: 10.1080/13510002.2016.1168589. Epub 2016 Apr 14.PMID: 27075937 Free PMC article.
It was found that chloride and bromide in concentration above 80 mM and thiocyanate in concentration above 20 muM enhance catalase inhibition by nitrite and the nitroso compounds more than 100 times. …This group acquires a positive charge in the active center of enzyme b …235Cite
Iron Supplements and Magnesium Peroxide: An Example of a Hazardous Combination in Self-Medication.
Vrolijk MF, Opperhuizen A, Jansen EH, Bast A, Haenen GR.Basic Clin Pharmacol Toxicol. 2016 Oct;119(4):412-7. doi: 10.1111/bcpt.12603. Epub 2016 May 4.PMID: 27061346 Free article.
To determine hydrogen peroxide formation by magnesium peroxide, a ferrous thiocyanate assay was performed. Finally, electron spin resonance spectroscopy (ESR) was performed to confirm the formation of hydroxyl radicals. …236Cite
Şahin F, Kıyan M, Karasartova D, Çalgın MK, Akhter S, Türegün Atasoy B.Mikrobiyol Bul. 2016 Jan;50(1):34-43. doi: 10.5578/mb.10685.PMID: 27058327 Free article. Turkish.
Nowadays molecular methods are widely used in the rapid diagnosis of infectious agents. Polymerase chain reaction (PCR) is the most preferred method for this purpose. …After that, the classic RNA extraction protocol using guanidinium thiocyanate-phenol-chloroform …237Cite
Reactive Oxygen Species and Neutrophil Function.
Winterbourn CC, Kettle AJ, Hampton MB.Annu Rev Biochem. 2016 Jun 2;85:765-92. doi: 10.1146/annurev-biochem-060815-014442. Epub 2016 Apr 6.PMID: 27050287 Review.238Cite
Sasidharan Pillai IM, Gupta AK.J Environ Manage. 2016 Jul 1;176:45-53. doi: 10.1016/j.jenvman.2016.03.021. Epub 2016 Mar 31.PMID: 27039363
Anodic oxidation of industrial wastewater from a coke oven plant having cyanide including thiocyanate (280 mg L(-1)), chemical oxygen demand (COD – 1520 mg L(-1)) and phenol (900 mg L(-1)) was carried out using a novel PbO2 anode. …Multivariate optimization was performed …239Cite
Pow EH, Chen Z, Kwong DL, Lam OL.PLoS One. 2016 Mar 31;11(3):e0152817. doi: 10.1371/journal.pone.0152817. eCollection 2016.PMID: 27031997 Free PMC article.
At 2 months following radiotherapy, there was a significant increase in chloride, sulphate, lactate and formate levels while significant reductions in nitrate and thiocyanate levels were found. No further changes in these anion levels were observed at 6 and 12 months. …C …240Cite
Omri Hichri A, Mosbah H, Majouli K, Besbes Hlila M, Ben Jannet H, Flamini G, Aouni M, Selmi B.Pharm Biol. 2016 Oct;54(10):2236-43. doi: 10.3109/13880209.2016.1151445. Epub 2016 Mar 17.PMID: 26983675 Free article.
Objective Investigation of the chemical composition antimicrobial and antioxidant activity of essential oils from Eruca longirostris leaves, stems, roots and fruits. …On the other hand, the oils of stems, fruits and roots showed significant antimicrobial activity …241Cite
Felker P, Bunch R, Leung AM.Nutr Rev. 2016 Apr;74(4):248-58. doi: 10.1093/nutrit/nuv110. Epub 2016 Mar 5.PMID: 26946249 Free PMC article. Review.
Using sulforaphane plasma levels following glucoraphanin ingestion as a surrogate for thiocyanate plasma concentrations after indole glucosinolate ingestion, the maximum thiocyanate contribution from indole glucosinolate degradation is estimated to be 10 muM, which …242Cite
Dimethyl trisulfide: A novel cyanide countermeasure.
Rockwood GA, Thompson DE, Petrikovics I.Toxicol Ind Health. 2016 Dec;32(12):2009-2016. doi: 10.1177/0748233715622713. Epub 2016 Mar 3.PMID: 26939832
The sulfur donor reactivity of DMTS was determined by measuring the rate of the formation of the cyanide metabolite thiocyanate. In experiments carried out in vitro in the presence of the sulfurtransferase rhodanese (Rh) and at the experimental pH of 7.4, DMTS was observed …243Cite
Love DT, Barrett TJ, White MY, Cordwell SJ, Davies MJ, Hawkins CL.Free Radic Biol Med. 2016 May;94:88-98. doi: 10.1016/j.freeradbiomed.2016.02.016. Epub 2016 Feb 17.PMID: 26898502
The ability of HOSCN to inhibit glycolysis and perturb energy production is likely to contribute to the cell death seen in macrophages on further incubation after the initial treatment period, which may be relevant for the propagation of inflammatory disease in smokers, who have …244Cite
Masoudiasl A, Montazerozohori M, Naghiha R, Assoud A, McArdle P, Safi Shalamzari M.Mater Sci Eng C Mater Biol Appl. 2016 Apr 1;61:809-23. doi: 10.1016/j.msec.2016.01.017. Epub 2016 Jan 11.PMID: 26838912
Zinc iodide and thiocyanate complexes crystallize in the monoclinic and triclinic systems with space groups of C2/c and P1- with eight and two molecules per unit cell respectively. …Moreover, ZnO nanoparticles were synthesized by direct thermolysis of zinc iodide complex …245Cite
Xue M, Zhang L, Zhan Z, Zou M, Huang Y, Zhao S.Talanta. 2016 Apr 1;150:324-30. doi: 10.1016/j.talanta.2015.12.024. Epub 2015 Dec 12.PMID: 26838415
A novel sulfur and nitrogen binary doped carbon dots (S,N-CDs) was synthesized by one-step manner through the hydrothermal treatment of citric acid (CA) and ammonium thiocyanate, and the procedures for biomedical applications, including probing doxycycline in living cells …246Cite
Antioxidant and ACE Inhibitory Bioactive Peptides Purified from Egg Yolk Proteins.
Yousr M, Howell N.Int J Mol Sci. 2015 Dec 7;16(12):29161-78. doi: 10.3390/ijms161226155.PMID: 26690134 Free PMC article.247Cite
Hafez HN, Alshammari AG, El-Gazzar AR.Acta Pharm. 2015 Dec;65(4):399-412. doi: 10.1515/acph-2015-0037.PMID: 26677897 Free article.
Reaction of 6-amino-3-methyl-4-(substituted phenyl)-1,4- dihydropyrano[2,3-c]pyrazole-5-carbonitrile (1) with triethylorthoformate followed by treatment with hydrazine hydrate, formic acid, acetic acid, phenylisocyanate, ammonium thiocyanate and formamide afforded the corr …248Cite
Effect of Thiocyanate on Iodine Status of Pregnant Women.
Bivolarska A, Gatseva P, Nikolova J, Argirova M, Atanasova V.Biol Trace Elem Res. 2016 Jul;172(1):101-107. doi: 10.1007/s12011-015-0583-1. Epub 2015 Dec 16.PMID: 26676231
There were negative correlations between urinary iodine levels and thiocyanate/creatinine ratio (R = -0.148, = 0.034) and between thiocyanate/creatinine ratio and FT4 (R = -0.379, p < 0.0001); thiocyanate/creatinine ratio and serum TSH were positively corr…249Cite
Komarnicka UK, Starosta R, Płotek M, de Almeida RF, Jeżowska-Bojczuk M, Kyzioł A.Dalton Trans. 2016 Mar 28;45(12):5052-63. doi: 10.1039/c5dt04011f.PMID: 26674970
In this paper we present a first insight into the cytotoxic action mode of copper(I) iodide or copper(I) thiocyanate complexes with a phosphine derivative of sparfloxacin (a 3rd generation fluoroquinolone antibiotic agent) and 2,9-dimethyl-1,10-phenanthroline or 2,2′-biqui …250Cite
Europium Luminescence Used for Logic Gate and Ions Sensing with Enoxacin As the Antenna.
Lu L, Chen C, Zhao D, Sun J, Yang X.Anal Chem. 2016 Jan 19;88(2):1238-45. doi: 10.1021/acs.analchem.5b03593. Epub 2015 Dec 22.PMID: 26643651251Cite
SYNTHESIS AND IN VITRO ANTIMICROBIAL ACTIVITY OF NOVEL SERIES OF 3,5-DIACETYLPYRIDINE COMPOUNDS.
Morsy EM, Kotb ER, Soliman HA, Sayyed HH, Abdelwahed NA.Acta Pol Pharm. 2015 May-Jun;72(3):465-74.PMID: 26642655 Free article.
Compound 4 was synthesized by reaction of 1 with potassium thiocyanate. Reaction of 4 with 4-chlorobenzaldehyde, glucose and phthalic or maleic anhydrides produced 5, 6 and 7a,b. …Some synthesized compounds were screened for their antimicrobial evaluation. Among t …252Cite
Disulfiram inhibition of cyanide formation after acetonitrile poisoning.
De Paepe P, Colin P, Depuydt P, Decavele AS, De Smet J, Boussery K, Stove C, Benoit D, Verstraete A, Van Bocxlaer J, Buylaert W.Clin Toxicol (Phila). 2016;54(1):56-60. doi: 10.3109/15563650.2015.1101770. Epub 2015 Dec 1.PMID: 26623950
He recovered from acetonitrile toxicity completely. The time course of acetonitrile, thiocyanate, and cyanide concentrations suggested that disulfiram inhibited cyanide formation. …253Cite
Gingerich A, Pang L, Hanson J, Dlugolenski D, Streich R, Lafontaine ER, Nagy T, Tripp RA, Rada B.Inflamm Res. 2016 Jan;65(1):71-80. doi: 10.1007/s00011-015-0892-z. Epub 2015 Nov 25.PMID: 26608498 Free PMC article.
OBJECTIVE AND DESIGN: Our aim was to study whether an extracellular, oxidative antimicrobial mechanism inherent to tracheal epithelial cells is capable of inactivating influenza H1N2 virus. …The dual oxidase/lactoperoxidase/thiocyanate extracellular oxidative syst …254Cite
Formation of cyanogen iodide by lactoperoxidase.
Schlorke D, Flemmig J, Birkemeyer C, Arnhold J.J Inorg Biochem. 2016 Jan;154:35-41. doi: 10.1016/j.jinorgbio.2015.11.005. Epub 2015 Nov 3.PMID: 26580225
Here we describe the formation of the inter(pseudo)halogen cyanogen iodide (ICN) by LPO. This product is formed when both, thiocyanate and iodide, are present together in the reaction mixture. Using (13)C nuclear magnetic resonance spectroscopy and gas chromatography-mass …255Cite
Lactoperoxidase as a potential drug target.
Flemmig J, Gau J, Schlorke D, Arnhold J.Expert Opin Ther Targets. 2016;20(4):447-61. doi: 10.1517/14728222.2016.1112378. Epub 2015 Nov 11.PMID: 26558497 Review.
The enzyme contributes in external secretions to the humoral immune defense against pathogens by oxidation of thiocyanate (SCN(-)) and iodide (I(-)). The generation of oxidized thiocyanate and/or iodine species is also important in numerous biotechnological applicat …256Cite
Del Prete S, Vullo D, Osman SM, AlOthman Z, Capasso C, Supuran CT.Bioorg Med Chem Lett. 2015 Nov 15;25(22):5194-8. doi: 10.1016/j.bmcl.2015.09.068. Epub 2015 Oct 3.PMID: 26459213
Here we present an anion inhibition study of this enzyme, reporting that metal complexing anions such as cyanate, thiocyanate, cyanide, azide are weak MgCA inhibitors (KIs ranging between 6.81 and 45.2 mM) whereas bicarbonate (KI of 0.59 mM) and diethyldithiocarbamate (KI …257Cite
Horton MK, Blount BC, Valentin-Blasini L, Wapner R, Whyatt R, Gennings C, Factor-Litvak P.Environ Res. 2015 Nov;143(Pt A):1-9. doi: 10.1016/j.envres.2015.09.013. Epub 2015 Sep 25.PMID: 26408806 Free PMC article.
Sodium/iodide symporter (NIS) inhibitors, namely perchlorate, nitrate, and thiocyanate, have been shown individually to competitively inhibit uptake of iodine by the thyroid. …CONCLUSIONS: Co-exposure to perchlorate, nitrate and thiocyanate may alter maternal thyr …258Cite
Al-Shehri SS, Knox CL, Liley HG, Cowley DM, Wright JR, Henman MG, Hewavitharana AK, Charles BG, Shaw PN, Sweeney EL, Duley JA.PLoS One. 2015 Sep 1;10(9):e0135047. doi: 10.1371/journal.pone.0135047. eCollection 2015.PMID: 26325665 Free PMC article.
Adult human saliva is low in hypoxanthine and xanthine, the substrates of XO, and high in the lactoperoxidase substrate thiocyanate, but saliva of neonates has not been examined. RESULTS: Median concentrations of hypoxanthine and xanthine in neonatal saliva (27 and 19 muM …259Cite
[ISOLATION OF ANTIBIOTICS RESISTANCE GENES IN VIBRIO CHOLERAE O1 AND O139 SEROGROUP STRAINS].
Zadnova SP, Smirnova NI.Zh Mikrobiol Epidemiol Immunobiol. 2015 May-Jun;(3):3-10.PMID: 26259263 Russian.
DNA isolation was carried out in the presence of 6M guanidine thiocyanate. PCR was carried out in multi-channel amplificator Tercyc. RESULTS: A multiplex PCR was constructed, that includes 5 primer pairs for the detection of O1 and O139 serogroup resistance genes of vibrio …260Cite
Nakano M, Shin K, Wakabayashi H, Yamauchi K, Abe F, Hironaka S.J Med Microbiol. 2015 Oct;64(10):1244-1252. doi: 10.1099/jmm.0.000150. Epub 2015 Aug 3.PMID: 26242770
The lactoperoxidase (LPO) system (consisting of LPO, glucose oxidase, glucose and thiocyanate) was previously shown to exhibit antimicrobial activities against some oral bacteria in vitro and suppressive effects on VSCs in mouth air in a clinical trial. …These res …261Cite
Khan I, Batista ML, Carvalho PJ, Santos LM, Gomes JR, Coutinho JA.J Phys Chem B. 2015 Aug 13;119(32):10287-303. doi: 10.1021/acs.jpcb.5b03324. Epub 2015 Jul 30.PMID: 26168205
Isobaric vapor-liquid equilibria of 1-butyl-3-methylimidazolium thiocyanate ([C4C1im][SCN]), 1-butyl-3-methylimidazolium dicyanamide ([C4C1im][N(CN)2]), 1-butyl-3-methylimidazolium tricyanomethanide ([C4C1im][C(CN)3]), and 1-ethyl-3-methylimidazolium tetracyanoborate ([C2C …262Cite
Mervish NA, Pajak A, Teitelbaum SL, Pinney SM, Windham GC, Kushi LH, Biro FM, Valentin-Blasini L, Blount BC, Wolff MS; Breast Cancer and Environment Research Project (BCERP).Environ Health Perspect. 2016 Apr;124(4):542-9. doi: 10.1289/ehp.1409309. Epub 2015 Jul 7.PMID: 26151950 Free PMC article.
BACKGROUND: Perchlorate, thiocyanate, and nitrate are sodium/iodide symporter (NIS) inhibitors that block iodide uptake into the thyroid, thus affecting thyroid function. …RESULTS: Compared with girls in the low-exposure group (3.6, 626, and 500 mg/gC, median perchlorate …263Cite
Wei X, Dong R, Wang D, Zhao T, Gao Y, Duffy P, Zhu X, Wang W.Chemistry. 2015 Aug 3;21(32):11427-34. doi: 10.1002/chem.201501317. Epub 2015 Jul 1.PMID: 26133314264Cite
Komarnicka UK, Starosta R, Kyzioł A, Jeżowska-Bojczuk M.Dalton Trans. 2015 Jul 28;44(28):12688-99. doi: 10.1039/c5dt01146a.PMID: 26085118
In this paper we present new copper(i) iodide or copper(i) thiocyanate complexes with hydroxymethyldiphenylphosphine (PPh2(CH2OH)) or phosphine derivatives of sparfloxacin, a 3(rd) generation fluoroquinolone antibiotic agent (PPh2(CH2-Sf)) and 2,9-dimethyl-1,10-phenanthrol …265Cite
Nematicidal Activity of the Volatilome of Eruca sativa on Meloidogyne incognita.
Aissani N, Urgeghe PP, Oplos C, Saba M, Tocco G, Petretto GL, Eloh K, Menkissoglu-Spiroudi U, Ntalli N, Caboni P.J Agric Food Chem. 2015 Jul 15;63(27):6120-5. doi: 10.1021/acs.jafc.5b02425. Epub 2015 Jun 26.PMID: 26082278
Testing of the nematicidal activity of rucola volatile compounds revealed that erucin, pentyl isothiocyanate, hexyl isothiocyanate, (E)-2-hexenal, 2-ethylfuran, and methyl thiocyanate were the most active with EC50 values of 3.2 1.7, 11.1 5.0, 11.3 2.6, 15.0 3.3, 16.0 5.0, …266Cite
Braakman RB, Sieuwerts AM, Umar A.Methods Mol Biol. 2015;1293:115-22. doi: 10.1007/978-1-4939-2519-3_6.PMID: 26040684
Protein-containing organic fractions of acid guanidinium thiocyanate-phenol-chloroform-extracted tissues are an interesting source of proteins as this method is widely used for RNA extraction for gene expression analysis. …Here we describe a protocol for an SDS-DTT-based …267Cite
Preparation and X-ray Structural Study of Dibenziodolium Derivatives.
Postnikov PS, Guselnikova OA, Yusubov MS, Yoshimura A, Nemykin VN, Zhdankin VV.J Org Chem. 2015 Jun 5;80(11):5783-8. doi: 10.1021/acs.joc.5b00741. Epub 2015 May 15.PMID: 25951091
Dibenziodolium hydrogen sulfate, bis(triflyl)imidate, or triflate can be readily converted to various other dibenziodolium derivatives (chloride, bromide, thiocyanate, azide, cyanide, phenylsulfinate) by anion exchange. Structures of key products have been established by s …268Cite
Aryloxyethyl Thiocyanates Are Potent Growth Inhibitors of Trypanosoma cruzi and Toxoplasma gondii.
Chao MN, Matiuzzi CE, Storey M, Li C, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB.ChemMedChem. 2015 Jun;10(6):1094-108. doi: 10.1002/cmdc.201500100. Epub 2015 Apr 27.PMID: 25914175 Free PMC article.
As a part of our project aimed at searching for new safe chemotherapeutic agents against parasitic diseases, several compounds structurally related to the antiparasitic agent WC-9 (4-phenoxyphenoxyethyl thiocyanate), which were modified at the terminal phenyl ring, …269Cite
Synthesis of some new bistriazolidine derivatives and their biological activity.
Yanni AS.Bioorg Khim. 2014 May-Jun;40(3):377-8.PMID: 25898746
Aromatic aldazines with thiocyanates in glacial acetic acid produce corresponding bistriazolidine derivatives via criss-cross cycloaddition reaction. …270Cite
Chandra AK, Mondal C, Sinha S, Chakraborty A, Pearce EN.Indian J Exp Biol. 2015 Mar;53(3):143-51.PMID: 25872244
Animals fed with the PSC-supplemented diet showed a significant increase in urinary excretion of thiocyanate and iodine, thyroid enlargement, and hypertrophy and/or hyperplasia of thyroid follicles. …271Cite
Iodine supplementation and drinking-water perchlorate mitigation.
Lewandowski TA, Peterson MK, Charnley G.Food Chem Toxicol. 2015 Jun;80:261-270. doi: 10.1016/j.fct.2015.03.014. Epub 2015 Mar 18.PMID: 25796570 Free article.
We also explored the effect of dietary exposures to nitrate and thiocyanate on iodine uptake and thyroid hormone production. Our modeling indicates that the level of thyroid hormone perturbation associated with perchlorate exposures in the range of current regulatory limit …272Cite
Almehdar HA, El-Fakharany EM, Uversky VN, Redwan EM.Curr Protein Pept Sci. 2015;16(4):352-65. doi: 10.2174/1389203716666150316114956.PMID: 25772156 Review.
Lactoferrin and lactoperoxidase (LPO) are known to possess prominent biocidal activity, serving as efficient antibiotics and antiviral agents against a wide spectrum of bacteria, fungi, and viruses. LPO is a heme-containing peroxidase expressed as preproprotein. …Functio …273Cite
A single protocol for extraction of gDNA from bacteria and yeast.
Vingataramin L, Frost EH.Biotechniques. 2015 Mar 1;58(3):120-5. doi: 10.2144/000114263. eCollection 2015 Mar.PMID: 25757544 Free article.
Guanidine thiocyanate breakage of microorganisms has been the standard initial step in genomic DNA (gDNA) extraction of microbial DNA for two decades, despite the requirement for pretreatments to extract DNA from microorganisms other than Gram-negative bacteria. …274Cite
Braakman RB, Bezstarosti K, Sieuwerts AM, de Weerd V, van Galen AM, Stingl C, Luider TM, Timmermans MA, Smid M, Martens JW, Foekens JA, Demmers JA, Umar A.J Proteome Res. 2015 Mar 6;14(3):1627-36. doi: 10.1021/acs.jproteome.5b00046. Epub 2015 Feb 2.PMID: 25611981
Acid guanidinium thiocyanate, phenol, and chloroform extraction (AGPC) is a commonly used procedure to extract RNA from fresh frozen tissues and cell lines. …275Cite
Biochemical mechanisms and therapeutic potential of pseudohalide thiocyanate in human health.
Chandler JD, Day BJ.Free Radic Res. 2015 Jun;49(6):695-710. doi: 10.3109/10715762.2014.1003372. Epub 2015 Jan 28.PMID: 25564094 Free PMC article. Review.
Thiocyanate (SCN(-)) is a ubiquitous molecule in mammalian biology, reaching up to mM concentrations in extracellular fluids. …276Cite
Human Z, Munyaneza A, Omondi B, Sanabria NM, Meijboom R, Cronjé MJ.Biometals. 2015 Feb;28(1):219-28. doi: 10.1007/s10534-014-9817-5. Epub 2014 Dec 30.PMID: 25547071
It is mainly diagnosed in the late stages, and patients tend to have a low 5-year survival rate of only 10%. Silver is generally used as an antimicrobial agent, with limited reports on anticancer studies. In this study, dimeric silver(I) thiocyanate complexes were u …277Cite
General and practical formation of thiocyanates from thiols.
Frei R, Courant T, Wodrich MD, Waser J.Chemistry. 2015 Feb 2;21(6):2662-8. doi: 10.1002/chem.201406171. Epub 2014 Dec 17.PMID: 25521497
The complete conversion of disulfides to thiocyanates was also possible. Preliminary computational studies indicated a low energy concerted transition state for the cyanation of the thiolate anion or radical. The developed thiocyanate synthesis has broad potential f …278Cite
Antiinflammatory and Antimicrobial Effects of Thiocyanate in a Cystic Fibrosis Mouse Model.
Chandler JD, Min E, Huang J, McElroy CS, Dickerhof N, Mocatta T, Fletcher AA, Evans CM, Liang L, Patel M, Kettle AJ, Nichols DP, Day BJ.Am J Respir Cell Mol Biol. 2015 Aug;53(2):193-205. doi: 10.1165/rcmb.2014-0208OC.PMID: 25490247 Free PMC article.
Thiocyanate (SCN) is used by the innate immune system, but less is known about its impact on inflammation and oxidative stress. …279Cite
Lau GP, Tsao HN, Yi C, Zakeeruddin SM, Grätzel M, Dyson PJ.ChemSusChem. 2015 Jan;8(2):255-9. doi: 10.1002/cssc.201403225. Epub 2014 Dec 8.PMID: 25488713
Furthermore, we identify a previously unreported pathway for device degradation, and show that the addition of N-methylbenzimidazole and a thiocyanate salt to the electrolyte is critical to obtaining long-lived devices….280Cite
Antimicrobial activity of allylic thiocyanates derived from the Morita-Baylis-Hillman reaction.
Sá MM, Ferreira M, Lima ES, dos Santos I, Orlandi PP, Fernandes L.Braz J Microbiol. 2014 Oct 9;45(3):807-12. doi: 10.1590/s1517-83822014000300007. eCollection 2014.PMID: 25477911 Free PMC article.
In this study, we carried out the screening of a family of allylic thiocyanates for their action against a diversity of bacteria and fungi with a view to developing new antimicrobial agents. …In particular cases, methyl (Z)-3-(2,4-dichlorophenyl)-2-(thiocya …281Cite
Futami J, Fujiyama H, Kinoshita R, Nonomura H, Honjo T, Tada H, Matsushita H, Abe Y, Kakimi K.PLoS One. 2014 Nov 18;9(11):e113295. doi: 10.1371/journal.pone.0113295. eCollection 2014.PMID: 25405999 Free PMC article.
The lysates were prepared from total cellular protein pellet extracted by using guanidinium thiocyanate-phenol-chloroform mixture of TRIzol, denatured and reduced total protein mixtures remained soluble after extensive dialysis against pure water. …282Cite
Fabrini R, Bocedi A, Camerini S, Fusetti M, Ottaviani F, Passali FM, Topazio D, Iavarone F, Francia I, Castagnola M, Ricci G.PLoS One. 2014 Nov 13;9(11):e112797. doi: 10.1371/journal.pone.0112797. eCollection 2014.PMID: 25393952 Free PMC article. Clinical Trial.283Cite
R PC, S NK, S M, S AK, B S DK.Appl Biochem Biotechnol. 2015 Jan;175(2):1247-61. doi: 10.1007/s12010-014-1335-y. Epub 2014 Nov 8.PMID: 25380641
The antioxidant potential of the extract was evaluated by nitric oxide radical inhibition, lipid peroxidation inhibition, ferric thiocyanate, and ABTS radical scavenging assay, and the extract recorded significant antioxidant activity. The ferric thiocyanate activit …284Cite
Choe J, Oh B, Choe E.J Food Sci. 2014 Nov;79(11):C2203-8. doi: 10.1111/1750-3841.12683. Epub 2014 Oct 13.PMID: 25312008
The effect of soybean lecithin addition on the iron-catalyzed or chlorophyll-photosensitized oxidation of emulsions consisting of purified canola oil and water (1:1, w/w) was studied based on headspace oxygen consumption using gas chromatography and hydroperoxide production using …285Cite
Mode of action of lactoperoxidase as related to its antimicrobial activity: a review.
Bafort F, Parisi O, Perraudin JP, Jijakli MH.Enzyme Res. 2014;2014:517164. doi: 10.1155/2014/517164. Epub 2014 Sep 16.PMID: 25309750 Free PMC article. Review.
Lactoperoxidase is a member of the family of the mammalian heme peroxidases which have a broad spectrum of activity. Their best known effect is their antimicrobial activity that arouses much interest in in vivo and in vitro applications. In this context, the proper use of …286Cite
de Macedo AN, Teo K, Mente A, McQueen MJ, Zeidler J, Poirier P, Lear SA, Wielgosz A, Britz-McKibbin P.Anal Chem. 2014 Oct 21;86(20):10010-5. doi: 10.1021/ac503231u. Epub 2014 Oct 8.PMID: 25280130
This assay also allows for simultaneous analysis of environmental iodide uptake inhibitors, including thiocyanate and nitrate. Rigorous method validation confirmed good linearity (R(2) = 0.9998), dynamic range (0.20 to 4.0 muM), accuracy (average recovery of 93% at three c …287Cite
Auer M, Nicolussi A, Schütz G, Furtmüller PG, Obinger C.J Biol Chem. 2014 Nov 7;289(45):31480-91. doi: 10.1074/jbc.M114.595157. Epub 2014 Sep 22.PMID: 25246525 Free PMC article.
Moreover, apparent bimolecular rate constants of the reaction of compound I with iodide, thiocyanate, bromide, and tyrosine increased significantly and became similar to LPO. Kinetic data are discussed and compared with known structure-function relationships of the mammali …288Cite
Liu X, Liu Y, Liang J, Shi L, Chu J, Li B.Hua Xi Kou Qiang Yi Xue Za Zhi. 2014 Aug;32(4):404-8. doi: 10.7518/hxkq.2014.04.020.PMID: 25241547 Free PMC article. Chinese.
OBJECTIVE: This study aimed to investigate the effect of a lactoperoxidase-peroxidase-thiocyanate (LPO-H2O-SCN-) system with different concentrations of iodine (I-) on Streptococcus mutans (S. mutans), particularly on various parameters, including growth, adhesion, glucosy …289Cite
Ohe TH, da Silva AA, Rocha Tda S, de Godoy FS, Franco DW.J Food Sci. 2014 Oct;79(10):C1950-5. doi: 10.1111/1750-3841.12587. Epub 2014 Sep 12.PMID: 25220490
Under optimal conditions (pH = 4.5, 40% ethanol), a concentration of 5.0 10(-6) mol/L cyanate can be determined in a single measurement, at a 95% level of confidence, with an uncertainty of 0.13 10(-6) mol/L. Cyanide, thiocyanate, chloride, nitrate, and sulfate ions, as we …290Cite
Moreau-Marquis S, Coutermarsh B, Stanton BA.J Antimicrob Chemother. 2015 Jan;70(1):160-6. doi: 10.1093/jac/dku357. Epub 2014 Sep 11.PMID: 25213272 Free PMC article.291Cite
Thompson RE, Duncan G, McCord BR.J Forensic Sci. 2014 Nov;59(6):1517-29. doi: 10.1111/1556-4029.12556. Epub 2014 Sep 3.PMID: 25182468
Inhibitors examined included calcium, humic acid, collagen, phenol, tannic acid, hematin, melanin, urea, bile salts, EDTA, and guanidinium thiocyanate. Results were plotted and modeled using mathematical simulations. In general, we found that PCR inhibitors that bind DNA a …292Cite
Removement of thiocyanate from industrial wastewater by microwave-Fenton oxidation method.
Xi B, Shi Q.J Environ Sci (China). 2013 Dec;25 Suppl 1:S201-4. doi: 10.1016/S1001-0742(14)60656-2.PMID: 25078832
The microwave radiation oxidation process, Fenton as catalytic agent, was used to remove the thiocyanate from the industrial wastewater. The effects of microwave power, radiation time, pH and the feeding in ways of catalyst on the degradation rate of synthetic wastewater w …293Cite
Emadi S, Behzadi M.Biochem Biophys Res Commun. 2014 Aug 8;450(4):1339-44. doi: 10.1016/j.bbrc.2014.06.133. Epub 2014 Jul 5.PMID: 25003319
In the present study, the effects on the aggregation of hen egg-white lysozyme via incubation in concentrated solutions of three different chaotropic agents namely guanidine thiocyanate, guanidine hydrochloride and urea were investigated. …Our results showed that …294Cite
Sokolov AV, Zakharova ET, Kostevich VA, Samygina VR, Vasilyev VB.Biometals. 2014 Oct;27(5):815-28. doi: 10.1007/s10534-014-9755-2. Epub 2014 Jun 26.PMID: 24966132
Upon immunoprecipitation of Cp, the blood plasma becomes depleted of Lf and in a dose-dependent manner loses the capacity to inhibit the peroxidase activity of Mpo, but not the Mpo-catalyzed oxidation of thiocyanate in the (pseudo)halogenating cycle. Antimicrobial e …295Cite
Uric acid and thiocyanate as competing substrates of lactoperoxidase.
Seidel A, Parker H, Turner R, Dickerhof N, Khalilova IS, Wilbanks SM, Kettle AJ, Jameson GN.J Biol Chem. 2014 Aug 8;289(32):21937-49. doi: 10.1074/jbc.M113.544957. Epub 2014 Jun 13.PMID: 24928513 Free PMC article.
LPO is a mammalian peroxidase that plays a key role in the innate immune defense by oxidizing thiocyanate to the bactericidal and fungicidal agent hypothiocyanite. We now demonstrate that urate is a good substrate for bovine LPO. …At physiologically relevant concentratio …296Cite
RNA extraction from equine samples for equine influenza virus.
Balasuriya UB.Methods Mol Biol. 2014;1161:379-92. doi: 10.1007/978-1-4939-0758-8_33.PMID: 24899447297Cite
Iodine deficiency, pollutant chemicals, and the thyroid: new information on an old problem.
Council on Environmental Health; Rogan WJ, Paulson JA, Baum C, Brock-Utne AC, Brumberg HL, Campbell CC, Lanphear BP, Lowry JA, Osterhoudt KC, Sandel MT, Spanier A, Trasande L.Pediatrics. 2014 Jun;133(6):1163-6. doi: 10.1542/peds.2014-0900.PMID: 24864180 Review.
Iodine deficiency, per se, can interfere with normal brain development in their offspring; in addition, it increases vulnerability to the effects of certain environmental pollutants, such as nitrate, thiocyanate, and perchlorate. Although pregnant and lactating women shoul …298Cite
Methanol concentration dependent protein denaturing ability of guanidinium/methanol mixed solution.
Shao Q.J Phys Chem B. 2014 Jun 12;118(23):6175-85. doi: 10.1021/jp500280v. Epub 2014 May 30.PMID: 24846320
In this article, the structure stability of a model protein (BdpA) in the mixture of guanidinium thiocyanate (GdmSCN) and methanol (MeOH) was investigated by molecular dynamics simulation. …299Cite
Spectroscopic studies on the antioxidant activity of ellagic acid.
Kilic I, Yeşiloğlu Y, Bayrak Y.Spectrochim Acta A Mol Biomol Spectrosc. 2014 Sep 15;130:447-52. doi: 10.1016/j.saa.2014.04.052. Epub 2014 May 2.PMID: 24813273
In vitro radical scavenging and antioxidant capacity of EA were clarified using different analytical methodologies such as total antioxidant activity determination by ferric thiocyanate, hydrogen peroxide scavenging, 1,1-diphenyl-2-picryl-hydrazyl free radical (DPPH) scave …300Cite
Mosconi N, Giulidori C, Velluti F, Hure E, Postigo A, Borthagaray G, Back DF, Torre MH, Rizzotto M.ChemMedChem. 2014 Jun;9(6):1211-20. doi: 10.1002/cmdc.201400071. Epub 2014 May 7.PMID: 24806993301Cite
Squalene synthase as a target for Chagas disease therapeutics.
Shang N, Li Q, Ko TP, Chan HC, Li J, Zheng Y, Huang CH, Ren F, Chen CC, Zhu Z, Galizzi M, Li ZH, Rodrigues-Poveda CA, Gonzalez-Pacanowska D, Veiga-Santos P, de Carvalho TM, de Souza W, Urbina JA, Wang AH, Docampo R, Li K, Liu YL, Oldfield E, Guo RT.PLoS Pathog. 2014 May 1;10(5):e1004114. doi: 10.1371/journal.ppat.1004114. eCollection 2014 May.PMID: 24789335 Free PMC article.
Trypanosomatid parasites are the causative agents of many neglected tropical diseases and there is currently considerable interest in targeting endogenous sterol biosynthesis in these organisms as a route to the development of novel anti–infective drugs. …W …302Cite
Charatcharoenwitthaya N, Ongphiphadhanakul B, Pearce EN, Somprasit C, Chanthasenanont A, He X, Chailurkit L, Braverman LE.J Clin Endocrinol Metab. 2014 Jul;99(7):2365-71. doi: 10.1210/jc.2013-3986. Epub 2014 Apr 4.PMID: 24701986
It is clear that perchlorate and thiocyanate anions can influence thyroid function. However, as pollutants in the environment, their impact is conflicting. …In multivariate analyses, thiocyanate exposure is also positively associated with TSH in a subgroup of preg …303Cite
Singh S, Das SS, Singh G, Schuff C, de Lampasona MP, Catalán CA.Biomed Res Int. 2014;2014:918209. doi: 10.1155/2014/918209. Epub 2014 Feb 6.PMID: 24689064 Free PMC article.
The antioxidant activity of essential oil and oleoresins was evaluated against linseed oil system at 200 ppm concentration by peroxide value, thiobarbituric acid value, ferric thiocyanate, ferrous ion chelating activity, and 1,1-diphenyl-2-picrylhydrazyl radical scavenging …304Cite
Vinogradova EV, Müller P, Buchwald SL.Angew Chem Int Ed Engl. 2014 Mar 17;53(12):3125-8. doi: 10.1002/anie.201310897.PMID: 24677728 Free PMC article.
Herein we present data showing that chlorobenziodoxole reacts with two different thiolate nucleophiles (thiocyanate and trifluoromethylthiolate), resulting in the formation of stable thioperoxy complexes rather than the expected benziodoxole derivatives. …305Cite
Chiniforoshan H, Tabrizi L, Hadizade M, Sabzalian MR, Chermahini AN, Rezapour M.Spectrochim Acta A Mol Biomol Spectrosc. 2014 Jul 15;128:183-90. doi: 10.1016/j.saa.2014.02.135. Epub 2014 Mar 12.PMID: 24667423
Zinc (II) complexes with non-steroidal anti-inflammatory drugs (NSAIDs) naproxen (nap) and ibuprofen (ibu) were synthesized in the presence of nitrogen donor ligands (thiocyanate or azide). The complexes were characterized by elemental analysis, FT-IR, (1)H NMR and UV-Vis …306Cite
Flemmig J, Rusch D, Czerwińska ME, Rauwald HW, Arnhold J.Arch Biochem Biophys. 2014 May 1;549:17-25. doi: 10.1016/j.abb.2014.03.006. Epub 2014 Mar 18.PMID: 24657078
By using excess hydrogen peroxide, we forced the accumulation of inactive enzymatic intermediates which are unable to promote the two-electronic oxidation of thiocyanate. Both OLE and certain extract components showed a strong LPO-reactivating effect. …307Cite
Comparative reactivity of myeloperoxidase-derived oxidants with mammalian cells.
Rayner BS, Love DT, Hawkins CL.Free Radic Biol Med. 2014 Jun;71:240-255. doi: 10.1016/j.freeradbiomed.2014.03.004. Epub 2014 Mar 13.PMID: 24632382 Review.308Cite
Shehab OR, Mansour AM.Biosens Bioelectron. 2014 Jul 15;57:77-84. doi: 10.1016/j.bios.2014.01.051. Epub 2014 Feb 4.PMID: 24556161309Cite
Iodine status in Turkish populations and exposure to iodide uptake inhibitors.
Ozpinar A, Kelestimur F, Songur Y, Can O, Valentin L, Caldwell K, Arikan E, Unsal I, Serteser M, Inal T, Erdemgil Y, Coskun A, Bakirci N, Sezgin O, Blount B.PLoS One. 2014 Feb 5;9(2):e88206. doi: 10.1371/journal.pone.0088206. eCollection 2014.PMID: 24505430 Free PMC article.
Perchlorate, nitrate, and thiocyanate are competitive inhibitors of the sodium iodide symporter of the thyroid membrane. …Further investigation is needed to characterize the thyroid impact resulting from iodine deficiency coupled with exposure to iodide uptake inhibitors …310Cite
Hu Y, Song Y, Horváth AK, Cui Y, Ji C, Zhao Y, Gao Q.Talanta. 2014 Mar;120:10-6. doi: 10.1016/j.talanta.2013.11.076. Epub 2013 Dec 3.PMID: 24468335
The hydrogen peroxide-thiocyanate reaction has been reinvestigated by means of capillary electrophoresis and high performance liquid chromatography under weakly alkaline conditions at 25.00.1 C. Concentration-time series of thiocyanate, sulfate and cyanate have been …311Cite
Singh P, Vishwakarma SP, Singh RL.J Sci Food Agric. 2014 Sep;94(12):2497-504. doi: 10.1002/jsfa.6585. Epub 2014 Feb 20.PMID: 24464686
The study was further carried out to assay the antimicrobial activity and HPLC analysis of plant parts. RESULTS: Ethanol extracts of leaf (early and mature) exhibited a high content of phenolics (54.79 and 41.28 g kg(-1) GAE) when it was compared with seed extract (23.85 g …312Cite
[High-quality total RNA extraction from medicinal plant Aquilaria sinensis].
Wu HQ, Wang L, Guo W, Gao XX, Bai L, Zhang WM.Zhong Yao Cai. 2013 Jul;36(7):1055-9.PMID: 24417137 Chinese.
METHODS: Five methods such as modified CTAB-LiCl method, modified CTAB-LiCl method with no water-bath, SDS-acid phenol method, modified guanidinium thiocyanate-CTAB method and EASYspin RN09 RNA isolation kit were used to extract RNA from leaves, branches, white wood sample …313Cite
Addition of multimodal therapy to standard management of steady state sickle cell disease.
Okpala I, Ezenwosu O, Ikefuna A, Duru A, Chukwu B, Madu A, Nwagha T, Ocheni S, Ibegbulam O, Emodi I, Anike U, Nonyelu C, Anigbo C, Agu K, Ajuba I, Chukwura A, Ugwu O, Ololo U.ISRN Hematol. 2013 Dec 9;2013:236374. doi: 10.1155/2013/236374. eCollection 2013.PMID: 24386573 Free PMC article.
Most people on folic acid to boost erythropoiesis and prophylactic antimicrobials, the standard management of steady state sickle cell disease (SCD), have unacceptable numbers of crises. The objective of this study was to evaluate the effects of adding multimodal therapy w …314Cite
Development of a colorimetric method for the dosage of OI- anions and I2 in aqueous media.
Bafort F, Barthelemy JP, Parisi O, Perraudin JP, Jijakli HM.Commun Agric Appl Biol Sci. 2014;79(1):155-60.PMID: 25864331 Free article.
Lactoperoxidase catalyzes the oxidation of thiocyanate (SCN-) and iodide (I-) in presence of hydrogen peroxide in hypothiocyanite (OSCN-) ions and, depending on the pH, in hypoiodite (OI-) ions or in iode (I2). …315Cite
Bakır T, Sönmezoğlu I, Imer F, Apak R.Int J Food Sci Nutr. 2014 Mar;65(2):226-34. doi: 10.3109/09637486.2013.845654. Epub 2013 Oct 24.PMID: 24152374
Cu(II)-induced LA peroxidation followed pseudo-first-order kinetics with respect to primary (hydroperoxides) and secondary (aldehydes- and ketones-like) oxidation products, which were determined by ferric thiocyanate and thiobarbituric acid-reactive substances methods, res …316Cite
Suh M, Abraham L, Hixon JG, Proctor DM.J Expo Sci Environ Epidemiol. 2014 Nov;24(6):579-87. doi: 10.1038/jes.2013.67. Epub 2013 Oct 23.PMID: 24149973
This study investigates the potential associations between urinary perchlorate, nitrate, and thiocyanate and serum free T4 in individuals with low urinary iodine levels and pregnant women. …TPO antibodies were significant predictors of free T4 among non-pregnant women on …317Cite
Lloyd MM, Grima MA, Rayner BS, Hadfield KA, Davies MJ, Hawkins CL.Free Radic Biol Med. 2013 Dec;65:1352-1362. doi: 10.1016/j.freeradbiomed.2013.10.007. Epub 2013 Oct 10.PMID: 24120969318Cite
Stark L, Giersch T, Wünschiers R.Anaerobe. 2014 Oct;29:85-90. doi: 10.1016/j.anaerobe.2013.09.007. Epub 2013 Oct 4.PMID: 24096086319Cite
Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents.
Elicio PD, Chao MN, Galizzi M, Li C, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB.Eur J Med Chem. 2013 Nov;69:480-9. doi: 10.1016/j.ejmech.2013.09.009. Epub 2013 Sep 18.PMID: 24090919 Free PMC article.
As a part of our project pointed at the search of new safe chemotherapeutic and chemoprophylactic agents against parasitic diseases, several compounds structurally related to 4-phenoxyphenoxyethyl thiocyanate (WC-9), which were modified at the terminal aromatic ring …320Cite
Derscheid RJ, van Geelen A, Berkebile AR, Gallup JM, Hostetter SJ, Banfi B, McCray PB Jr, Ackermann MR.Am J Respir Cell Mol Biol. 2014 Feb;50(2):389-97. doi: 10.1165/rcmb.2012-0529OC.PMID: 24053146 Free PMC article.
This three-component system consists of the hydrogen peroxide (H2O2)-producing enzymes dual oxidase (Duox)1 and Duox2, thiocyanate (SCN(-)), and secreted lactoperoxidase (LPO). The LPO-catalyzed reaction between H2O2 and SCN(-) yields the bactericidal hypothiocyanite (OSCN …321Cite
El-Dean AM, Zaki RM, Geies AA, Radwan SM, Tolba MS.Bioorg Khim. 2013 Sep-Oct;39(5):619-30.PMID: 25702421
Reaction of Ghloroacetylamino with potassium thiocyanate yielded ethylpyrimidothieno coumarin sulfanylacetate which was used as a versatile precursor for synthesis of other heterocycles. …322Cite
[Study of antioxidant and membrane activity of rosmarinic acid using different model systems].
Popov AM, Osipov AN, Korepanova EA, Krivoshapko ON, Artiukov AA.Biofizika. 2013 Sep-Oct;58(5):775-85.PMID: 25481945 Russian.
Linoleic acid peroxidation was assessed by iron-thiocyanate method. In these studies, trolox was used as a reference antioxidant, and ascorbic acid, and dihydroquercetin were taken as standards. …323Cite
St Denis TG, Vecchio D, Zadlo A, Rineh A, Sadasivam M, Avci P, Huang L, Kozinska A, Chandran R, Sarna T, Hamblin MR.Free Radic Biol Med. 2013 Dec;65:800-810. doi: 10.1016/j.freeradbiomed.2013.08.162. Epub 2013 Aug 19.PMID: 23969112 Free PMC article.
Antimicrobial photodynamic therapy (PDT) is used for the eradication of pathogenic microbial cells and involves the light excitation of dyes in the presence of O2, yielding reactive oxygen species including the hydroxyl radical (OH) and singlet oxygen ((1)O2). In order to …324Cite
Spectroscopic studies on the antioxidant activity of p-coumaric acid.
Kiliç I, Yeşiloğlu Y.Spectrochim Acta A Mol Biomol Spectrosc. 2013 Nov;115:719-24. doi: 10.1016/j.saa.2013.06.110. Epub 2013 Jul 8.PMID: 23892112
In vitro radical scavenging and antioxidant capacity of p-coumaric acid were clarified using different analytical methodologies such as total antioxidant activity determination by ferric thiocyanate, hydrogen peroxide scavenging, 1,1-diphenyl-2-picryl-hydrazyl free radical …325Cite
Snider GW, Ruggles E, Khan N, Hondal RJ.Biochemistry. 2013 Aug 13;52(32):5472-81. doi: 10.1021/bi400462j. Epub 2013 Jul 31.PMID: 23865454 Free PMC article.326Cite
Euphorbia characias latex amine oxidase and peroxidase: interacting enzymes?
Pintus F, Spanò D, Floris G, Medda R.Protein J. 2013 Aug;32(6):435-41. doi: 10.1007/s10930-013-9501-6.PMID: 23839010 Review.
This minireview deals the enzymatic transformation of some amino acids as arginine and ornithine, amines as tyramine, putrescine, spermine and spermidine, and other substances as nitric oxide and thiocyanate. These reactions, catalyzed by two proteins purified from the lat …327Cite
Glutathione and γ-glutamylcysteine in hydrogen peroxide detoxification.
Quintana-Cabrera R, Bolaños JP.Methods Enzymol. 2013;527:129-44. doi: 10.1016/B978-0-12-405882-8.00007-6.PMID: 23830629
Whereas most assays rely on coupled enzymatic reactions, this method determines the formation of a ferric thiocyanate derivative after direct Fe(2+) oxidation by H2O2. Here, we detail the procedure and considerations to determine H2O2 reduction by both gammaGC and GSH, eit …328Cite
Affum AO, Lowor S, Osae SD, Dickson A, Gyan BA, Tulasi D.Malar J. 2013 Jun 28;12:220. doi: 10.1186/1475-2875-12-220.PMID: 23809666 Free PMC article.
The International Pharmacopoeia and Global Pharma Health Fund Minilab protocols were used to assess the quality of anti-malarial tablets per blisterpacks allegedly manufactured by Guilin Pharmaceutical Co Ltd, China (GPCL) and Letap Pharmaceuticals Ltd, Ghana (LPL) and sold in ch …329Cite
An approach to the phytochemical profiling of rocket [Eruca sativa (Mill.) Thell].
Villatoro-Pulido M, Priego-Capote F, Álvarez-Sánchez B, Saha S, Philo M, Obregón-Cano S, De Haro-Bailón A, Font R, Del Río-Celestino M.J Sci Food Agric. 2013 Dec;93(15):3809-19. doi: 10.1002/jsfa.6286. Epub 2013 Jul 24.PMID: 23794443330Cite
Pan P, Vermelho AB, Scozzafava A, Parkkila S, Capasso C, Supuran CT.Bioorg Med Chem. 2013 Aug 1;21(15):4472-6. doi: 10.1016/j.bmc.2013.05.058. Epub 2013 Jun 6.PMID: 23790722
TcCA was inhibited in the low micromolar range by iodide, cyanate, thiocyanate, hydrogensulfide and trithiocarbonate (KIs in the range of 44-93 muM), but the best inhibitor was diethyldithiocarbamate (KI=5 muM). …The discovery of diethyldithiocarbamate as a low micromola …331Cite
Invited review: The effect of native and nonnative enzymes on the flavor of dried dairy ingredients.
Campbell RE, Drake MA.J Dairy Sci. 2013 Aug;96(8):4773-83. doi: 10.3168/jds.2013-6598. Epub 2013 Jun 13.PMID: 23769377 Free article. Review.332Cite
Takadanohara H, Catanzaro R, Chui de H, He F, Yadav H, Ganguli A, Sakata Y, Solimene U, Minelli E, Kobayashi R, Nagamachi Y, Marotta F.Acta Biomed. 2012 Dec;83(3):208-16.PMID: 23762997
Body weight, food and water intake and passage of stool pellet during stress session were recorded throughout the experiment. On the 11th day, fluorescent iso-thiocyanate dextran solution was injected into small intestinal loops. One hour after the injection, rats were sac …333Cite
Oxidation of thiocyanate with H2O2 catalyzed by [Ru(III)(edta)(H2O)]-.
Chatterjee D, Paul B, Mukherjee R.Dalton Trans. 2013 Jul 21;42(27):10056-60. doi: 10.1039/c3dt50723h. Epub 2013 May 29.PMID: 23714771
The [Ru(III)(edta)(H2O)](-) (edta(4-) = ethylenediaminetetraacetate) complex is shown to catalyze the oxidation of thiocyanate (SCN(-)) with H2O2 mimicking the action of peroxidases. The kinetics of the catalytic oxidation process was studied by using stopped-flow and rapi …334Cite
Seiberlich V, Borchert J, Zhukareva V, Richter-Landsberg C.Cell Biochem Biophys. 2013 Sep;67(1):149-60. doi: 10.1007/s12013-013-9622-8.PMID: 23686611335Cite
Nebulized thiocyanate improves lung infection outcomes in mice.
Chandler JD, Min E, Huang J, Nichols DP, Day BJ.Br J Pharmacol. 2013 Jul;169(5):1166-77. doi: 10.1111/bph.12206.PMID: 23586967 Free PMC article.
The benefits of these therapies include improved lung function, phlegm clearance and fewer lung infections. The thiocyanate anion (SCN) is a normal component of the airway epithelial lining fluid (ELF) secreted by pulmonary epithelia with antioxidant and host defence funct …336Cite
Urease from Helicobacter pylori is inactivated by sulforaphane and other isothiocyanates.
Fahey JW, Stephenson KK, Wade KL, Talalay P.Biochem Biophys Res Commun. 2013 May 24;435(1):1-7. doi: 10.1016/j.bbrc.2013.03.126. Epub 2013 Apr 11.PMID: 23583386 Free PMC article.337Cite
In vitro antiviral activity of hypothiocyanite against A/H1N1/2009 pandemic influenza virus.
Cegolon L, Salata C, Piccoli E, Juarez V, Palu’ G, Mastrangelo G, Calistri A.Int J Hyg Environ Health. 2014 Jan;217(1):17-22. doi: 10.1016/j.ijheh.2013.03.001. Epub 2013 Mar 14.PMID: 23540488338Cite
Sahariah BP, Chakraborty S.Environ Technol. 2013 Jan-Feb;34(1-4):245-56. doi: 10.1080/09593330.2012.692712.PMID: 23530337
Synthetic wastewater contained phenol (1500 mg/l), thiocyanate (SCN(-)800 mg/l at gradual fill and 100 mg/l at instantaneous fill) and ammonia (NH4(+)-N 500 mg/l). …339Cite
Jain RB.Chemosphere. 2013 May;91(7):882-7. doi: 10.1016/j.chemosphere.2013.02.040. Epub 2013 Mar 19.PMID: 23522032
The reverse was true for thiocyanate levels. There was an inverse association between nitrate and education levels. …Also, new to this study, of concern, was the fact that levels of these contaminants increased among females over the period 2005-2008. Levels of perchlora …340Cite
Ghorab MM, Ismail ZH, Radwan AA, Abdalla M.Acta Pharm. 2013 Mar;63(1):1-18. doi: 10.2478/acph-2013-0006.PMID: 23482309 Free article.
The synthesized compounds were screened for their in vitro antimicrobial activities and some of them exhibited promising antibacterial activity compared to ampicillin as positive control. …341Cite
Steinmaus C, Miller MD, Cushing L, Blount BC, Smith AH.Environ Res. 2013 May;123:17-24. doi: 10.1016/j.envres.2013.01.005. Epub 2013 Mar 7.PMID: 23473920 Free PMC article.
Perchlorate, thiocyanate, and low iodine intake can all decrease iodide intake into the thyroid gland. …Overall, these results suggest that concomitant exposure to perchlorate, thiocyanate, and low iodine markedly reduces thyroxine production. This highlights the …342Cite
Andersen SL, Nøhr SB, Wu CS, Olsen J, Pedersen KM, Laurberg P.Eur J Endocrinol. 2013 Apr 15;168(5):723-31. doi: 10.1530/EJE-12-0759. Print 2013 May.PMID: 23444413
The sodium iodide symporter (NIS) mediates active iodide transport into the thyroid and the lactating mammary gland and is also present in placenta. NIS is competitively inhibited by thiocyanate from maternal smoking, but compensatory autoregulation of iodide transport dif …343Cite
Kalpana Deepa Priya D, Gayathri R, Gunassekaran GR, Murugan S, Sakthisekaran D.Pharm Biol. 2013 May;51(5):621-8. doi: 10.3109/13880209.2012.761242. Epub 2013 Feb 4.PMID: 23373711 Free article.344Cite
Kalmár J, Lente G, Fábián I.Inorg Chem. 2013 Feb 18;52(4):2150-6. doi: 10.1021/ic302544y. Epub 2013 Jan 30.PMID: 23363374
The haloperoxidase-catalyzed in vivo oxidation of thiocyanate ion (SCN(-)) by H(2)O(2) is important for generation of the antimicrobial hypothiocyanite ion (OSCN(-)), which is also susceptible to oxidation by strong in vivo oxidizing agents (i.e., H(2)O(2), O …345Cite
Jensen JS, Fan X, Guidot DM.Am J Respir Cell Mol Biol. 2013 Apr;48(4):511-7. doi: 10.1165/rcmb.2012-0334OC.PMID: 23306837 Free PMC article.346Cite
Identification of aldo-keto reductases as NRF2-target marker genes in human cells.
Jung KA, Choi BH, Nam CW, Song M, Kim ST, Lee JY, Kwak MK.Toxicol Lett. 2013 Mar 27;218(1):39-49. doi: 10.1016/j.toxlet.2012.12.026. Epub 2013 Jan 7.PMID: 23305850347Cite
Yang L, Qu M, Wang Y, Duan H, Chen P, Wang Y, Shi W, Danielson P, Zhou Q.Mol Pharmacol. 2013 Mar;83(3):671-80. doi: 10.1124/mol.112.081059. Epub 2013 Jan 2.PMID: 23284002348Cite
Oloyede GK, Oyelola MS.EXCLI J. 2013 Oct 28;12:894-906. eCollection 2013.PMID: 27092035 Free PMC article.
Chew (Urticaceae), used in ethno medicine as antioxidant and antimicrobial were studied. The aim of this research work was to isolate and characterize the bio-active compounds in the n-hexane fraction of L. aestuans, determine the toxicity and subject it to in-vitro ant …349Cite
Miller DM, Singh IN, Wang JA, Hall ED.Free Radic Biol Med. 2013 Apr;57:1-9. doi: 10.1016/j.freeradbiomed.2012.12.011. Epub 2012 Dec 27.PMID: 23275005 Free PMC article.350Cite
Hunger J, Neueder R, Buchner R, Apelblat A.J Phys Chem B. 2013 Jan 17;117(2):615-22. doi: 10.1021/jp311425v. Epub 2013 Jan 3.PMID: 23241014
From this analysis, we find no evidence for significant ion association in aqueous solutions of guanidinium chloride (GdmCl) and guanidinium thiocyanate (GdmSCN), and the molar conductivity of these electrolytes can be modeled assuming a complete dissociation. …351Cite
Excessive iodine intake, water chemicals and endemic goitre in a Sudanese coastal area.
Medani AM, Elnour AA, Saeed AM.Public Health Nutr. 2013 Sep;16(9):1586-92. doi: 10.1017/S1368980012004685. Epub 2012 Nov 16.PMID: 23206325 Free PMC article.
Measurements determined the prevalence of goitre, urinary iodine concentration and thiocyanate secretion in casual urine samples, serum levels of thyroxine, triiodothyronine, thyroid-stimulating hormone and thyroglobulin, as well as the levels of Cl-, F-, Ca2+, Mg2+ and to …352Cite
Deary ME, Durrant MC, Davies DM.Org Biomol Chem. 2013 Jan 14;11(2):309-17. doi: 10.1039/c2ob26842f. Epub 2012 Nov 28.PMID: 23188177 Free article.
In the present paper, we extend our study of the borate-peroxide system to look at a wide range of substrates that include substituted dimethyl anilines, methyl-p-tolyl sulfoxide, halides, hydrogen sulfide anion, thiosulfate, thiocyanate, and hydrazine. The unusual selecti …353Cite
Role of bamboo-shoot in the pathogenesis of endemic goiter in manipur, north East India.
Chandra AK, Singh LH, Ghosh S, Pearce EN.Endocr Pract. 2013 Jan-Feb;19(1):36-45. doi: 10.4158/EP12162.OR.PMID: 23186959
METHODS: Goiter prevalence, urinary iodine, and thiocyanate (SCN) excretion in school children, iodine content in drinking water, and the household consumption of salt fortified with iodine were measured. …354Cite
Ion segregation in aqueous solutions.
Bian H, Li J, Zhang Q, Chen H, Zhuang W, Gao YQ, Zheng J.J Phys Chem B. 2012 Dec 13;116(49):14426-32. doi: 10.1021/jp310153n. Epub 2012 Dec 3.PMID: 23181902355Cite
Ahameethunisa AR, Hopper W.Ann Clin Microbiol Antimicrob. 2012 Nov 21;11:30. doi: 10.1186/1476-0711-11-30.PMID: 23171441 Free PMC article.
BACKGROUND: Artemisia parviflora leaf extracts were evaluated for potential antimicrobial and antioxidant properties. Antimicrobial susceptibility assay was performed against ten standard reference bacterial strains. Antioxidant activity was analyzed using the ferri …356Cite
Distinct effects of guanidine thiocyanate on the structure of superfolder GFP.
Stepanenko OV, Stepanenko OV, Kuznetsova IM, Shcherbakova DM, Verkhusha VV, Turoverov KK.PLoS One. 2012;7(11):e48809. doi: 10.1371/journal.pone.0048809. Epub 2012 Nov 7.PMID: 23144981 Free PMC article.
Here, we studied the unfolding-refolding of sfGFP that was induced by guanidine thiocyanate (GTC), which is a stronger denaturing agent than GdnHCl or urea. Structural perturbations of sfGFP were studied by spectroscopic methods (absorbance, fluorescence, and circular dich …357Cite
Targeting iron uptake to control Pseudomonas aeruginosa infections in cystic fibrosis.
Smith DJ, Lamont IL, Anderson GJ, Reid DW.Eur Respir J. 2013 Dec;42(6):1723-36. doi: 10.1183/09031936.00124012. Epub 2012 Nov 8.PMID: 23143541 Free article. Review.
As part of chronic infection P. aeruginosa forms biofilms, which shield the encased bacteria from host immune clearance and provide an impermeable and protective barrier against currently available antimicrobial agents. P. aeruginosa has an absolute requirement for …358Cite
Poma HR, Davies C, Gutiérrez Cacciabue D, Mora MC, Basombrío MÁ, Rajal VB.Rev Argent Microbiol. 2012 Jul-Sep;44(3):144-9.PMID: 23102460 Spanish.359Cite
Sulforaphane causes a major epigenetic repression of myostatin in porcine satellite cells.
Fan H, Zhang R, Tesfaye D, Tholen E, Looft C, Hölker M, Schellander K, Cinar MU.Epigenetics. 2012 Dec 1;7(12):1379-90. doi: 10.4161/epi.22609. Epub 2012 Oct 23.PMID: 23092945 Free PMC article.360Cite
Li X, Reynal A, Barnes P, Humphry-Baker R, Zakeeruddin SM, De Angelis F, O’Regan BC.Phys Chem Chem Phys. 2012 Nov 28;14(44):15421-8. doi: 10.1039/c2cp43347h. Epub 2012 Oct 15.PMID: 23070136
From FTIR results and molecular modelling we show the iodine binds to the thiocyanate group in all these dyes. For the AR24 dye we present evidence that iodine also binds to the amine moiety on this dye. …We leave open the question why iodine binding to the amine group s …361Cite
Shao Q, Gao YQ.J Chem Phys. 2012 Oct 14;137(14):145101. doi: 10.1063/1.4757419.PMID: 23061865362Cite
Rees MD, Dang L, Thai T, Owen DM, Malle E, Thomas SR.Free Radic Biol Med. 2012 Dec 15;53(12):2344-56. doi: 10.1016/j.freeradbiomed.2012.10.002. Epub 2012 Oct 9.PMID: 23059132 Free PMC article.
Notably, diversion of MPO from HOCl production by thiocyanate or nitrite attenuated de-adhesion and associated signaling responses, despite the latter substrate supporting MPO-catalyzed fibronectin nitration. …363Cite
Dueñas-García IE, Santos-Cruz LF, Castañeda-Partida L, Castañeda-Sortibrán AN, Ordaz-Téllez MG, Sánchez-Santos A, Durán-Díaz A, Rodríguez-Arnaiz R, Heres-Pulido ME.Food Chem Toxicol. 2012 Dec;50(12):4479-86. doi: 10.1016/j.fct.2012.09.003. Epub 2012 Sep 28.PMID: 23026699364Cite
Bruce GM, Corey LM, Mandel JH, Pleus RC.J Occup Environ Med. 2013 Jan;55(1):52-8. doi: 10.1097/JOM.0b013e31826bb774.PMID: 23018524
OBJECTIVE: To determine, on the basis of iodide uptake inhibition (IUI), whether associations between urinary concentrations of IUI agents (perchlorate, nitrate, and thiocyanate), as total perchlorate equivalent concentration (PEC), and serum thyroid parameters sugg …365Cite
Li H, Cao Z, Zhang G, Thannickal VJ, Cheng G.Free Radic Biol Med. 2012 Nov 15;53(10):1954-9. doi: 10.1016/j.freeradbiomed.2012.08.597. Epub 2012 Sep 12.PMID: 22982576 Free PMC article.366Cite
Kawaguchi K, Nakamura T, Kamiie J, Takahashi T, Yamamoto N.Biosci Biotechnol Biochem. 2012;76(9):1792-5. doi: 10.1271/bbb.120299. Epub 2012 Sep 7.PMID: 22972320 Free article.
The antihypertensive peptides, Val-Pro-Pro and Ile-Pro-Pro, were successfully detected in the aorta of spontaneously hypertensive rats after orally administering these peptides by a guanidine-thiocyanate treatment to prevent proteolysis. Cy3-labeled versions of both peptid …367Cite
Allylic thiocyanates as a new class of antitubercular agents.
Silveira GP, Ferreira M, Fernandes L, Moraski GC, Cho S, Hwang C, Franzblau SG, Sá MM.Bioorg Med Chem Lett. 2012 Oct 15;22(20):6486-9. doi: 10.1016/j.bmcl.2012.08.048. Epub 2012 Aug 21.PMID: 22967767
We found a selective group of new and promising compounds having good (micromolar) to excellent (sub-micromolar) potency against replicating Mtb H(37)Rv. Allylic thiocyanates bearing halophenyl (halo=2-Br, 4-Br, 4-Cl, 4-F), 4-methylphenyl and 2-naphthyl moieties were the m …368Cite
Huang GJ, Deng JS, Chen HJ, Huang SS, Liao JC, Hou WC, Lin YH.Food Chem. 2012 Dec 1;135(3):861-7. doi: 10.1016/j.foodchem.2012.05.082. Epub 2012 May 29.PMID: 22953797
Antioxidant status [2,2′-azinobis[3-ethylbenzthiazoline-6-sulphonic acid (ABTS) assay], scavenging activity against DPPH (1,1-dipheny-2-picrylhydrazyl) radical method, reducing power method, Fe(2+)-chelating ability, FTC (ferric thiocyanate) method, and protection of calf …369Cite
Lamy E, Oey D, Eißmann F, Herz C, Münstedt K, Tinneberg HR, Mersch-Sundermann V.Phytother Res. 2013 Jul;27(7):1036-41. doi: 10.1002/ptr.4798. Epub 2012 Sep 5.PMID: 22949403370Cite
Pezo D, Navascués B, Salafranca J, Nerín C.Anal Chim Acta. 2012 Oct 1;745:92-8. doi: 10.1016/j.aca.2012.07.038. Epub 2012 Aug 1.PMID: 22938611
Ethyl Lauroyl Arginate (LAE) is a cationic tensoactive compound, soluble in water, with a wide activity spectrum against moulds and bacteria. LAE has been incorporated as antimicrobial agent into packaging materials for food contact and these materials require to comply wi …371Cite
Evaluation of methods for the isolation of high quality RNA from bovine and cervine hide biopsies.
Brannan JL, Holman PJ, Olafson PU, Pruett JH, Riggs PK.J Parasitol. 2013 Feb;99(1):19-23. doi: 10.1645/GE-3132.1. Epub 2012 Aug 27.PMID: 22924936372Cite
Singh AK, Smith ML, Yamini S, Ohlsson PI, Sinha M, Kaur P, Sharma S, Paul JA, Singh TP, Paul KG.Protein J. 2012 Oct;31(7):598-608. doi: 10.1007/s10930-012-9436-3.PMID: 22886082
Lactoperoxidase (LPO) is a hemeprotein catalyzing the oxidation of thiocyanate and I(-) into antimicrobials and small aromatic organics after being itself oxidized by H(2)O(2). …373Cite
Silkina A, Bazes A, Mouget JL, Bourgougnon N.Mar Pollut Bull. 2012 Oct;64(10):2039-46. doi: 10.1016/j.marpolbul.2012.06.028. Epub 2012 Jul 31.PMID: 22853990
The application of ‘booster biocides’ Diuron, Tolylfluanid and Copper thiocyanate inbantifouling paints, used to prevent development of biofouling, needs to be monitored before assessing their impacts on the environment. …374Cite
Ruggiero A, Marchant J, Squeglia F, Makarov V, De Simone A, Berisio R.J Biomol Struct Dyn. 2013;31(2):195-205. doi: 10.1080/07391102.2012.698243. Epub 2012 Jul 25.PMID: 22831279
To gain insight into the inactivation mechanism of one of the most promising RpfB inhibitors, 4-benzoyl-2-nitrophenyl thiocyanate, NPT7, we have performed replica exchange molecular dynamics (REMD) simulations, starting from the crystal structure of RpfB catalytic domain, …375Cite
Environmental perchlorate and thiocyanate exposures and infant serum thyroid function.
Leung AM, Braverman LE, He X, Schuller KE, Roussilhes A, Jahreis KA, Pearce EN.Thyroid. 2012 Sep;22(9):938-43. doi: 10.1089/thy.2012.0058. Epub 2012 Jul 24.PMID: 22827469 Free PMC article.
There were no correlations between infant TSH or FT4 and iodine, perchlorate, and thiocyanate levels in breast milk, maternal urine, and infant urine. In multivariable analyses, perchlorate and thiocyanate levels in breast milk, maternal urine, and infant urine were …376Cite
[Antibacterial mechanism of sulforaphane on Escherichia coli].
Wu HZ, Fei HJ, Zhao YL, Liu XJ, Huang YJ, Wu SW.Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 May;43(3):386-90.PMID: 22812243 Chinese.377Cite
Campbell Y, Fantacone ML, Gombart AF.Eur J Nutr. 2012 Dec;51(8):899-907. doi: 10.1007/s00394-012-0415-4. Epub 2012 Jul 15.PMID: 22797470 Free PMC article. Review.
BACKGROUND: Antimicrobial peptides (AMPs) are synthesized and secreted by immune and epithelial cells that are constantly exposed to environmental microbes. …METHODS: The present review examines the published data from both in vitro and in vivo studies reporting the effe …378Cite
Activation of the stress proteome as a mechanism for small molecule therapeutics.
Brose RD, Shin G, McGuinness MC, Schneidereith T, Purvis S, Dong GX, Keefer J, Spencer F, Smith KD.Hum Mol Genet. 2012 Oct 1;21(19):4237-52. doi: 10.1093/hmg/dds247. Epub 2012 Jul 2.PMID: 22752410 Free PMC article.
Various small molecule pharmacologic agents with different known functions produce similar outcomes in diverse Mendelian and complex disorders, suggesting that they may induce common cellular effects. …Treatment of human fibroblasts with these four agents induced …379Cite
Nrf2-ARE pathway regulates induction of Sestrin-2 expression.
Shin BY, Jin SH, Cho IJ, Ki SH.Free Radic Biol Med. 2012 Aug 15;53(4):834-41. doi: 10.1016/j.freeradbiomed.2012.06.026. Epub 2012 Jun 26.PMID: 22749810380Cite
Supplemental iodine as a key to reproduction in pandas?
Milewski AV, Dierenfeld ES.Integr Zool. 2012 Jun;7(2):175-82. doi: 10.1111/j.1749-4877.2012.00283.x.PMID: 22691201
Pandas are endemic to iodine-poor environments and appear to be specialized for a goitrogenic staple diet. In particular, the importance of thiocyanate in bamboos might possibly have been overlooked in captive breeding programs. Although excreted in urine, thiocyanate …381Cite
Wiczk A, Hofman D, Konopa G, Herman-Antosiewicz A.Biochim Biophys Acta. 2012 Aug;1823(8):1295-305. doi: 10.1016/j.bbamcr.2012.05.020. Epub 2012 May 25.PMID: 22640870 Free article.382Cite
Antioxidant properties of various solvent extracts from purple basil.
Yeşiloğlu Y, Sit L.Spectrochim Acta A Mol Biomol Spectrosc. 2012 Sep;95:100-6. doi: 10.1016/j.saa.2012.04.036. Epub 2012 May 3.PMID: 22613128383Cite
The use of lactoperoxidase for the bleaching of fluid whey.
Campbell RE, Kang EJ, Bastian E, Drake MA.J Dairy Sci. 2012 Jun;95(6):2882-90. doi: 10.3168/jds.2011-5166.PMID: 22612925 Free article.
Lactoperoxidase (LP) is the second most abundant enzyme in bovine milk and has been used in conjunction with hydrogen peroxide (H2O2) and thiocyanate (SCN-) to work as an antimicrobial in raw milk where pasteurization is not feasible. Thiocyanate is naturally …384Cite
Kratschmar DV, Calabrese D, Walsh J, Lister A, Birk J, Appenzeller-Herzog C, Moulin P, Goldring CE, Odermatt A.PLoS One. 2012;7(5):e36774. doi: 10.1371/journal.pone.0036774. Epub 2012 May 11.PMID: 22606287 Free PMC article.385Cite
Protective effects of isothiocyanates on blood-CSF barrier disruption induced by oxidative stress.
Xiang J, Alesi GN, Zhou N, Keep RF.Am J Physiol Regul Integr Comp Physiol. 2012 Jul 1;303(1):R1-7. doi: 10.1152/ajpregu.00518.2011. Epub 2012 May 9.PMID: 22573102 Free PMC article.386Cite
Toward an understanding of bisretinoid autofluorescence bleaching and recovery.
Yamamoto K, Zhou J, Hunter JJ, Williams DR, Sparrow JR.Invest Ophthalmol Vis Sci. 2012 Jun 8;53(7):3536-44. doi: 10.1167/iovs.12-9535.PMID: 22570342 Free PMC article.387Cite
Synthesis and bioactivity of pyrazole acyl thiourea derivatives.
Wu J, Shi Q, Chen Z, He M, Jin L, Hu D.Molecules. 2012 May 3;17(5):5139-50. doi: 10.3390/molecules17055139.PMID: 22555301 Free PMC article.
Thess were then reacted with ammonium thiocyanate in the presence of PEG-400 to afford 5-chloro-3-methyl-1-substituted-1H-pyrazole-4-carbonyl isothiocyanates 5. …388Cite
Effect of chronic excess iodine intake on thyroid function and oxidative stress in hypothyroid rats.
Hussein Ael-A, Abbas AM, El Wakil GA, Elsamanoudy AZ, El Aziz AA.Can J Physiol Pharmacol. 2012 May;90(5):617-25. doi: 10.1139/y2012-046. Epub 2012 May 2.PMID: 22550940
Sixty rats were divided into euthyroid and hypothyroid (thiocyanate-induced) groups with or without administration of excess iodine (3000 or 6000 mug/L) for 8 weeks. …Excess iodine significantly increased MDA and antioxidants in euthyroid and hypothyroid rats. In conclus …389Cite
Shukla A, Burton NM, Jayaraman PS, Gaston K.PLoS One. 2012;7(4):e35984. doi: 10.1371/journal.pone.0035984. Epub 2012 Apr 23.PMID: 22540015 Free PMC article.390Cite
Pearce EN, Alexiou M, Koukkou E, Braverman LE, He X, Ilias I, Alevizaki M, Markou KB.Clin Endocrinol (Oxf). 2012 Sep;77(3):471-4. doi: 10.1111/j.1365-2265.2012.04407.x.PMID: 22486757
MEASUREMENTS: Urinary iodide, perchlorate, and thiocyanate and thyroid function tests were measured. RESULTS: The median urinary iodide was 120 mug/l. …In multivariate analyses adjusting for urinary iodide concentrations, urine thiocyanate, gestational age, matern …391Cite
Hwang JW, Kim EK, Lee SJ, Kim YS, Moon SH, Jeon BT, Sung SH, Kim ET, Park PJ.J Agric Food Chem. 2012 May 2;60(17):4282-8. doi: 10.1021/jf205321j. Epub 2012 Apr 17.PMID: 22380882
The inhibitory effect of anthocyanin oligomers on lipid peroxidation was examined with ferric thiocyanate (FTC) and thiobarbituric acid (TBA). The inhibitory activity of anthocyanin oligomers was found to be comparable to that of vitamin E. …392Cite
Pattison DI, Davies MJ, Hawkins CL.Free Radic Res. 2012 Aug;46(8):975-95. doi: 10.3109/10715762.2012.667566. Epub 2012 Apr 23.PMID: 22348603 Review.
The major reactive species produced by MPO under physiological conditions are hypochlorous acid (HOCl) and hypothiocyanous acid (HOSCN), with the ratio of these oxidants critically dependent on the concentration of thiocyanate ions (SCN-). The reactivity and selectivity of …393Cite
Akhtar MJ, Ahamed M, Fareed M, Alrokayan SA, Kumar S.J Toxicol Sci. 2012 Feb;37(1):139-48. doi: 10.2131/jts.37.139.PMID: 22293418 Free article.394Cite
Oskoueian E, Abdullah N, Hendra R, Karimi E.Int J Mol Sci. 2011;12(12):8610-25. doi: 10.3390/ijms12128610. Epub 2011 Nov 29.PMID: 22272095 Free PMC article.
Methanolic extracts of rapeseed meal showed significantly (P < 0.01) higher phenolics and flavonoids contents; and significantly (P < 0.01) higher DPPH and nitric oxide free radical scavenging activities when compared to that of cottonseed meal and soybean meal extracts. Fe…395Cite
Synthesis, reactions and antimicrobial activities of 8-ethoxycoumarin derivatives.
Mohamed HM, Abd El-Wahab AH, Ahmed KA, El-Agrody AM, Bedair AH, Eid FA, Khafagy MM.Molecules. 2012 Jan 18;17(1):971-88. doi: 10.3390/molecules17010971.PMID: 22258342 Free PMC article.
The newly synthesized compounds were also screened for their antimicrobial activity….396Cite
Liu C, Li J, Wang L, Wu F, Huang L, Xu Y, Ye J, Xiao B, Meng F, Chen S, Yang M.BMC Complement Altern Med. 2012 Jan 16;12:5. doi: 10.1186/1472-6882-12-5.PMID: 22248096 Free PMC article.397Cite
Taher M, Susanti D, Rezali MF, Zohri FS, Ichwan SJ, Alkhamaiseh SI, Ahmad F.Asian Pac J Trop Med. 2012 Feb;5(2):136-41. doi: 10.1016/S1995-7645(12)60012-1.PMID: 22221758 Free article.
OBJECTIVE: To study the chemical constituents of stembark of Garcinia malaccensis (G. malaccensis) together with apoptotic, antimicrobial and antioxidant activities. METHODS: Purification and structure elucidation were carried out by chromatographic and spectroscopic techn …398Cite
Souza CE, Maitra D, Saed GM, Diamond MP, Moura AA, Pennathur S, Abu-Soud HM.PLoS One. 2011;6(11):e27641. doi: 10.1371/journal.pone.0027641. Epub 2011 Nov 22.PMID: 22132121 Free PMC article.
Lactoperoxidase (LPO) is the major consumer of hydrogen peroxide (H(2)O(2)) in the airways through its ability to oxidize thiocyanate (SCN(-)) to produce hypothiocyanous acid, an antimicrobial agent. In nasal inflammatory diseases, such as cystic fibrosis, both LPO …399Cite
Alfieri KN, Vienneau AR, Londergan CH.Biochemistry. 2011 Dec 27;50(51):11097-108. doi: 10.1021/bi200903p. Epub 2011 Dec 2.PMID: 22103476 Free PMC article.
The synthetic antimicrobial peptide CM15, a hybrid of N-terminal sequences from cecropin and melittin peptides, has been shown to be extremely potent. …400Cite
Antioxidant, anti-inflammatory and cytotoxicity of Phaleria macrocarpa (Boerl.) Scheff Fruit.
Hendra R, Ahmad S, Oskoueian E, Sukari A, Shukor MY.BMC Complement Altern Med. 2011 Nov 9;11:110. doi: 10.1186/1472-6882-11-110.PMID: 22070850 Free PMC article.
Pericarp and mesocarp showed high antioxidant activities by using DPPH (71.97%, 62.41%), ferric reducing antioxidant power (92.35%, 78.78%) and NO scavenging activity (65.68%, 53.45%). Ferric thiocyanate and thiobarbituric acid tests showed appreciable antioxidant activity …
Lee YJ, Lee SH.J Korean Med Sci. 2011 Nov;26(11):1474-82. doi: 10.3346/jkms.2011.26.11.1474. Epub 2011 Oct 27.PMID: 22065904 Free PMC article.402Cite
Kensler TW, Ng D, Carmella SG, Chen M, Jacobson LP, Muñoz A, Egner PA, Chen JG, Qian GS, Chen TY, Fahey JW, Talalay P, Groopman JD, Yuan JM, Hecht SS.Carcinogenesis. 2012 Jan;33(1):101-7. doi: 10.1093/carcin/bgr229. Epub 2011 Nov 1.PMID: 22045030 Free PMC article. Clinical Trial.403Cite
Mechanism of decomposition of the human defense factor hypothiocyanite near physiological pH.
Kalmár J, Woldegiorgis KL, Biri B, Ashby MT.J Am Chem Soc. 2011 Dec 14;133(49):19911-21. doi: 10.1021/ja2083152. Epub 2011 Nov 18.PMID: 22031955404Cite
Meinertz JR, Schreier TM, Bernardy JA.Bull Environ Contam Toxicol. 2011 Dec;87(6):621-5. doi: 10.1007/s00128-011-0415-8. Epub 2011 Oct 9.PMID: 21984684
Approval of a new animal drug application for AQUAMYCIN 100() (erythromycin thiocyanate; ET) to treat freshwater salmonid species with bacterial kidney disease is being pursued in the US. …405Cite
Merenbloom SI, Flick TG, Daly MP, Williams ER.J Am Soc Mass Spectrom. 2011 Nov;22(11):1978-90. doi: 10.1007/s13361-011-0238-1. Epub 2011 Sep 13.PMID: 21952780 Free PMC article.
The gas-phase conformations of ubiquitin, cytochrome c, lysozyme, and alpha-lactalbumin ions, formed by electrospray ionization (ESI) from aqueous solutions containing 5 mM ammonium perchlorate, ammonium iodide, ammonium sulfate, ammonium chloride, ammonium thiocyanate, or …406Cite
Microbial inactivation for safe and rapid diagnostics of infectious samples.
Sagripanti JL, Hülseweh B, Grote G, Voss L, Böhling K, Marschall HJ.Appl Environ Microbiol. 2011 Oct;77(20):7289-95. doi: 10.1128/AEM.05553-11. Epub 2011 Aug 19.PMID: 21856830 Free PMC article.
The high risk associated with biological threat agents dictates that any suspicious sample be handled under strict surety and safety controls and processed under high-level containment in specialized laboratories. …Formaldehyde, hydrogen peroxide, and guanidium thiocy …407Cite
Isoeugenol-based novel potent antioxidants: synthesis and reactivity.
Fındık E, Ceylan M, Elmastaş M.Eur J Med Chem. 2011 Sep;46(9):4618-24. doi: 10.1016/j.ejmech.2011.07.041. Epub 2011 Jul 28.PMID: 21843909
Antioxidant and radical scavenging activities of synthesized compounds (7-12) were determined by using various in vitro assays such as 1,1-diphenyl-2-picrylhydrazyl free radicals (DPPH), 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radicals (ABTS(+)), and superoxide anio …408Cite
Deactivation efficiency of stabilized bactericidal emulsions.
Vyhnalkova R, Eisenberg A, van de Ven TG.Langmuir. 2011 Sep 20;27(18):11296-305. doi: 10.1021/la201112j. Epub 2011 Aug 22.PMID: 21823610
Biocide emulsions stabilized with various stabilizing agents were prepared and characterized, and their efficiency in bacteria deactivation was evaluated. A number of stabilizing agents were tested for their stabilizing effect on emulsions of thiocyanomethylthiobenz …409Cite
Rojanarata T, Sumran K, Nateetaweewat P, Winotapun W, Sukpisit S, Opanasopit P, Ngawhirunpat T.Talanta. 2011 Sep 15;85(3):1324-9. doi: 10.1016/j.talanta.2011.06.009. Epub 2011 Jun 15.PMID: 21807190
Interestingly, the amount of nitric acid, silver nitrate, ferric alum and ammonium thiocyanate consumed in the miniaturized titration was reduced by the factors of 25, 50, 50 and 215 times, respectively. …410Cite
Choi K, Chen J, Mitra S, Sarna SK.Gastroenterology. 2011 Oct;141(4):1293-301, 1301.e1-3. doi: 10.1053/j.gastro.2011.06.074. Epub 2011 Jul 13.PMID: 21745450 Free PMC article.411Cite
Synthesis of biologically active heterocycles from coumarin thiocyanate.
Langi BP, Mulwad VV, Chaskar AC.Acta Pol Pharm. 2011 May-Jun;68(3):441-6.PMID: 21648200 Free article. No abstract available.412Cite
Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties.
Göçer H, Gülçin I.Int J Food Sci Nutr. 2011 Dec;62(8):821-5. doi: 10.3109/09637486.2011.585963. Epub 2011 Jun 2.PMID: 21631390
The aim of this study was to determine the antioxidant activity of CAPE using different methods such as total antioxidant activity by the thiocyanate method, 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid radicals, 1,1-diphenyl-2-picryl-hydrazyl free radicals, N,N-d …413Cite
Rajendran P, Delage B, Dashwood WM, Yu TW, Wuth B, Williams DE, Ho E, Dashwood RH.Mol Cancer. 2011 May 30;10:68. doi: 10.1186/1476-4598-10-68.PMID: 21624135 Free PMC article.
BACKGROUND: Histone deacetylase (HDAC) inhibitors are currently undergoing clinical evaluation as anti-cancer agents. Dietary constituents share certain properties of HDAC inhibitor drugs, including the ability to induce global histone acetylation, turn-on epigenetically-s …414Cite
Nrf-2 regulates cyclosporine-stimulated HO-1 expression in gingiva.
Chin YT, Liao YW, Fu MM, Tu HP, Shen EC, Nieh S, Shih KC, Fu E.J Dent Res. 2011 Aug;90(8):995-1000. doi: 10.1177/0022034511410698. Epub 2011 May 27.PMID: 21622902415Cite
Welk A, Rudolph P, Kreth J, Schwahn Ch, Kramer A, Below H.Arch Oral Biol. 2011 Dec;56(12):1576-82. doi: 10.1016/j.archoralbio.2011.04.016. Epub 2011 May 28.PMID: 21621190
OBJECTIVE: As shown in the quantitative suspension test adding lactoperoxidase to a thiocyanate (SCN(-)) hydrogen peroxide (H(2)O(2)) combination over the physiological saliva level has significant positive antimicrobial effects to a level of totally killing Strepto …416Cite
Iodine status and thyroid function of Boston-area vegetarians and vegans.
Leung AM, Lamar A, He X, Braverman LE, Pearce EN.J Clin Endocrinol Metab. 2011 Aug;96(8):E1303-7. doi: 10.1210/jc.2011-0256. Epub 2011 May 25.PMID: 21613354 Free PMC article.
The iodine status and thyroid function of U.S. vegetarians and vegans have not been previously studied. Environmental perchlorate and thiocyanate (inhibitors of thyroid iodine uptake) exposures may adversely affect thyroid function. …Adjusted for cigarette smoking (confi …417Cite
The host defense proteome of human and bovine milk.
Hettinga K, van Valenberg H, de Vries S, Boeren S, van Hooijdonk T, van Arendonk J, Vervoort J.PLoS One. 2011 Apr 27;6(4):e19433. doi: 10.1371/journal.pone.0019433.PMID: 21556375 Free PMC article.
The human newborn is known to be deficient for at least two of these proteins (immunoglobulin A and CD14). On the other hand, antimicrobial proteins (5 cathelicidins and lactoperoxidase) were abundant in bovine milk. The high concentration of lactoperoxidase is probably li …418Cite
Infrared emission following photolysis of methylisothiocyanate and methylthiocyanate.
Wade EA, Pore JL, Osborn DL.J Phys Chem A. 2011 Jun 2;115(21):5319-23. doi: 10.1021/jp2000305. Epub 2011 May 9.PMID: 21553839419Cite
Sulforaphane protects human chondrocytes against cell death induced by various stimuli.
Facchini A, Stanic I, Cetrullo S, Borzì RM, Filardo G, Flamigni F.J Cell Physiol. 2011 Jul;226(7):1771-9. doi: 10.1002/jcp.22506.PMID: 21506109420Cite
Sahariah BP, Chakraborty S.J Hazard Mater. 2011 Jun 15;190(1-3):260-7. doi: 10.1016/j.jhazmat.2011.03.038. Epub 2011 Mar 21.PMID: 21497997
A simulated wastewater containing phenol (2500 mg/L), thiocyanate and ammonia-nitrogen (500 mg/L) was treated in an anaerobic (R1)-anoxic (R2)-aerobic (R3) moving bed biofilm reactor system at different hydraulic retention time (HRT) intervals (total HRT 3-8 days, R1: 1.5- …421Cite
Investigations of different chemiluminescent peaks in H2O2-SCN(-)-Cu(2+)-OH(-)-luminol flow system.
Zhao C, Zheng J, Xie J, Liu H, Gao Q.Luminescence. 2011 Mar-Apr;26(2):130-5. doi: 10.1002/bio.1195.PMID: 21491564422Cite
Touré A, Xu X, Michel T, Bangoura M.Nat Prod Res. 2011 Jul;25(11):1025-36. doi: 10.1080/14786419.2010.482048.PMID: 21480049
The antioxidant properties of the water and ethanol leaf extracts of kinkeliba (Combretum micranthum) were investigated, including scavenging of the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical (IC50 values: 8.02 0.34 for the ethanol extract [KE] and 9.1 0.28 for the water extrac …423Cite
Enhancement of respiratory mucosal antiviral defenses by the oxidation of iodide.
Fischer AJ, Lennemann NJ, Krishnamurthy S, Pócza P, Durairaj L, Launspach JL, Rhein BA, Wohlford-Lenane C, Lorentzen D, Bánfi B, McCray PB Jr.Am J Respir Cell Mol Biol. 2011 Oct;45(4):874-81. doi: 10.1165/rcmb.2010-0329OC. Epub 2011 Mar 25.PMID: 21441383 Free PMC article.
The other components include epithelial ion transporters, which mediate the secretion of the oxidizable anion thiocyanate (SCN(-)) into airway surface liquid, and lactoperoxidase (LPO), which catalyzes the H(2)O(2)-dependent oxidation of the pseudohalide SCN(-) to yield th …424Cite
Sánchez-Rodríguez A, Sosa-Ferrera Z, Santana-del Pino A, Santana-Rodríguez JJ.Mar Pollut Bull. 2011 May;62(5):985-91. doi: 10.1016/j.marpolbul.2011.02.038. Epub 2011 Mar 10.PMID: 21396664425Cite
Concurrent sulforaphane and eugenol induces differential effects on human cervical cancer cells.
Hussain A, Priyani A, Sadrieh L, Brahmbhatt K, Ahmed M, Sharma C.Integr Cancer Ther. 2012 Jun;11(2):154-65. doi: 10.1177/1534735411400313. Epub 2011 Mar 7.PMID: 21382956 Free article.
BACKGROUND: The concept of combination of chemoprevention holds great potential for cancer management as lower, clinically tolerable doses of individual agents could be achieved through therapeutic synergy. However, elucidation of their possible interactions–additive, syn …426Cite
Medani AM, Elnour AA, Saeed AM.Bull World Health Organ. 2011 Feb 1;89(2):121-6. doi: 10.2471/BLT.09.075002. Epub 2010 Oct 22.PMID: 21346923 Free PMC article.
Serum levels of thyroxine (T4), triiodothyronine (T3) and thyroid-stimulating hormone (TSH), as well as urinary secretion of thiocyanate, which can affect the transport of iodine into thyrocytes, were also measured. …427Cite
Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions.
Lorentzen D, Durairaj L, Pezzulo AA, Nakano Y, Launspach J, Stoltz DA, Zamba G, McCray PB Jr, Zabner J, Welsh MJ, Nauseef WM, Bánfi B.Free Radic Biol Med. 2011 May 1;50(9):1144-50. doi: 10.1016/j.freeradbiomed.2011.02.013. Epub 2011 Feb 18.PMID: 21334431 Free PMC article.
A recently discovered enzyme system produces antibacterial hypothiocyanite (OSCN(-)) in the airway lumen by oxidizing the secreted precursor thiocyanate (SCN(-)). Airway epithelial cultures have been shown to secrete SCN(-) in a CFTR-dependent manner. …428Cite
Harada N, Kanayama M, Maruyama A, Yoshida A, Tazumi K, Hosoya T, Mimura J, Toki T, Maher JM, Yamamoto M, Itoh K.Arch Biochem Biophys. 2011 Apr 1;508(1):101-9. doi: 10.1016/j.abb.2011.02.001. Epub 2011 Feb 12.PMID: 21303654429Cite
Bactericidal block copolymer micelles.
Vyhnalkova R, Eisenberg A, van de Ven T.Macromol Biosci. 2011 May 12;11(5):639-51. doi: 10.1002/mabi.201000428. Epub 2011 Jan 27.PMID: 21275041430Cite
Antitrypanasomal activity of novel benzaldehyde-thiosemicarbazone derivatives from kaurenoic acid.
Haraguchi SK, Silva AA, Vidotti GJ, dos Santos PV, Garcia FP, Pedroso RB, Nakamura CV, de Oliveira CM, da Silva CC.Molecules. 2011 Jan 26;16(2):1166-80. doi: 10.3390/molecules16021166.PMID: 21270733 Free PMC article.
The results show that the structural modifications accomplished enhanced the antitrypanosomal activity of these compounds. Besides, the thiocyanate, thiosemicarbazide and the p- methyl, p-methoxy, p-dimethylamine, m-nitro and o-chlorobenzaldehyde-thiosemicarbazone derivati …431Cite
Prevention of DNA double-strand breaks induced by radioiodide-(131)I in FRTL-5 thyroid cells.
Hershman JM, Okunyan A, Rivina Y, Cannon S, Hogen V.Endocrinology. 2011 Mar;152(3):1130-5. doi: 10.1210/en.2010-1163. Epub 2010 Dec 29.PMID: 21190956 Free PMC article.
Incubation with 20-100 mum iodide or thiocyanate markedly attenuated DSBs. Perchlorate was about 6 times more potent than iodide or thiocyanate(.) …In conclusion, we developed a thyroid cell model to quantify the mitogenic effect of (131)I. (131)I causes DNA DSBs …432Cite
Seed-mediated growth of palladium nanocrystals: the effect of pseudo-halide thiocyanate ions.
Zhang L, Niu W, Xu G.Nanoscale. 2011 Feb;3(2):678-82. doi: 10.1039/c0nr00622j. Epub 2010 Dec 17.PMID: 21170425
In synthesis in a solution phase, adsorbates such as halides can interact selectively with different metal crystal facets and affect the final morphology of nanocrystals. Pseudo-halide thiocyanate ions (SCN-) can also adsorb on the metal surface, but they have never been u …433Cite
Jeong SI, Choi BM, Jang SI.Arch Pharm Res. 2010 Nov;33(11):1867-76. doi: 10.1007/s12272-010-1120-6. Epub 2010 Nov 30.PMID: 21116791434Cite
Keshteli AH, Hashemipour M, Siavash M, Amini M.World J Pediatr. 2010 Nov;6(4):357-60. doi: 10.1007/s12519-010-0236-6. Epub 2010 Nov 16.PMID: 21080148
In the present study we investigated the possible role of thiocyanate as a goitrogen in the etiology of goiter in Isfahan, Iran. METHODS: A total of 2331 (6-13 year old) school children were selected by multistage random sampling. …Urinary iodine concentration (UIC) and …435Cite
Meinertz JR, Schreier TM, Bernardy JA, Franz JL.Bull Environ Contam Toxicol. 2010 Nov;85(5):447-51. doi: 10.1007/s00128-010-0117-7. Epub 2010 Oct 23.PMID: 20976439
Diphenhydramine hydrochloride (DH; Benadryl, an over-the-counter antihistamine) and erythromycin thiocyanate (ET; a commonly used macrolide antibiotic) are pharmaceutical compounds whose chronic toxicity to Daphnia magna had not been characterized. …436Cite
Reszka KJ, Sallans L, Macha S, Brown K, McGraw DW, Kovacic MB, Britigan BE.J Pharmacol Exp Ther. 2011 Feb;336(2):440-9. doi: 10.1124/jpet.110.170027. Epub 2010 Oct 25.PMID: 20974700 Free PMC article.
Salbutamol nitration was inhibited in vitro by ascorbate, thiocyanate, and the pharmacological agents methimazole and dapsone. The efficacy of inhibition depended on the nitrating system, with the lactoperoxidase/H(2)O(2)/NO(2)(-) being the most affected. …437Cite
Sánchez-Rodríguez A, Sosa-Ferrera Z, Santana-Rodríguez JJ.Chemosphere. 2011 Jan;82(1):96-102. doi: 10.1016/j.chemosphere.2010.09.064. Epub 2010 Oct 13.PMID: 20947123438Cite
Antioxidant properties of Urtica pilulifera root, seed, flower, and leaf extract.
Ozen T, Cöllü Z, Korkmaz H.J Med Food. 2010 Oct;13(5):1224-31. doi: 10.1089/jmf.2009.1303.PMID: 20828318
Antioxidative activity of the extracts was measured using the ferric thiocyanate method, thiobarbituric acid method, reductive potential, metal chelating, free radical, superoxide anion radical, and hydrogen peroxide scavenging activity. …439Cite
Pintus F, Spanò D, Bellelli A, Angelucci F, Scorciapino AM, Anedda R, Medda R, Floris G.Biochemistry. 2010 Oct 12;49(40):8739-47. doi: 10.1021/bi1007854. Epub 2010 Sep 16.PMID: 20822104
The oxidation of the pseudohalide thiocyanate (SCN(-)) by Euphorbia peroxidase, in the presence or absence of added calcium, is investigated. After incubation of the native enzyme with hydrogen peroxide, the formation of Compound I occurs and serves to catalyze the thio …440Cite
Wharfe ES, Jarvis RM, Winder CL, Whiteley AS, Goodacre R.Environ Microbiol. 2010 Dec;12(12):3253-63. doi: 10.1111/j.1462-2920.2010.02300.x.PMID: 20649644
Chemical and physical remediation of this wastewater removes the majority of these pollutants; however, these processes do not remove phenol and thiocyanate. The removal of these compounds has been effected during bioremediation with activated sludge containing a complex m …441Cite
Bozonet SM, Scott-Thomas AP, Nagy P, Vissers MC.Free Radic Biol Med. 2010 Sep 15;49(6):1054-63. doi: 10.1016/j.freeradbiomed.2010.06.028. Epub 2010 Jul 13.PMID: 20615463442Cite
The effects of peroxidase on the enzymatic and candidacidal activities of lysozyme.
Lee JY, Kim YY, Chang JY, Park MS, Kho HS.Arch Oral Biol. 2010 Sep;55(9):607-12. doi: 10.1016/j.archoralbio.2010.06.001. Epub 2010 Jun 29.PMID: 20591411
The influence of the peroxidase system on lysozyme was examined by the subsequent addition of potassium thiocyanate and hydrogen peroxide. Lysozyme activity was determined by the turbidity measurement of a Micrococcus lysodeikticus substrate suspension. …The enhancement …443Cite
Asakura Y, Narumi S, Muroya K, Fujita K, Aida N, Hasagawa T, Adachi M.Am J Med Genet A. 2010 Jul;152A(7):1793-7. doi: 10.1002/ajmg.a.33456.PMID: 20583162
Thyroidal iodine uptake was also increased during goiter progression ((123)I uptake at 24 hr: 20.2% at age 17 years; 69.4% at age 24 years; reference, 8-40), while serum thyrotropin (TSH) levels and iodine organification (examined by the perchrolate or thiocyanate discharg …444Cite
Mi L, Sirajuddin P, Gan N, Wang X.Anal Biochem. 2010 Oct 15;405(2):269-71. doi: 10.1016/j.ab.2010.06.015. Epub 2010 Jun 10.PMID: 20541518 Free PMC article.445Cite
Agretti P, Dimida A, De Marco G, Ferrarini E, Rodrìguez Gonzàlez JC, Santini F, Vitti P, Pinchera A, Tonacchera M.J Endocrinol Invest. 2011 Mar;34(3):170-4. doi: 10.1007/BF03347061. Epub 2010 May 17.PMID: 20479570446Cite
Moon JK, Kim JR, Ahn YJ, Shibamoto T.J Agric Food Chem. 2010 Jun 9;58(11):6672-7. doi: 10.1021/jf1003573.PMID: 20459098447Cite
Perchlorate and thiocyanate exposure and thyroid function in first-trimester pregnant women.
Pearce EN, Lazarus JH, Smyth PP, He X, Dall’amico D, Parkes AB, Burns R, Smith DF, Maina A, Bestwick JP, Jooman M, Leung AM, Braverman LE.J Clin Endocrinol Metab. 2010 Jul;95(7):3207-15. doi: 10.1210/jc.2010-0014. Epub 2010 Apr 28.PMID: 20427488
It is unclear whether environmental perchlorate exposure adversely affects thyroid function in pregnant women. Thiocyanate, derived from foods and cigarette smoke, is a less potent competitive sodium/iodide symporter inhibitor than perchlorate. …MAIN OUTCOME MEASURES: Ur …448Cite
Shan Y, Zhao R, Geng W, Lin N, Wang X, Du X, Wang S.Cardiovasc Toxicol. 2010 Jun;10(2):139-45. doi: 10.1007/s12012-010-9072-0.PMID: 20405237449Cite
Hemodialysis complications of hydroxocobalamin: a case report.
Sutter M, Tereshchenko N, Rafii R, Daubert GP.J Med Toxicol. 2010 Jun;6(2):165-7. doi: 10.1007/s13181-010-0067-9.PMID: 20352539 Free PMC article.
Cyanide level, drawn 20 min after the antidote was completed, was elevated at 22 mcg/dL. Her urinary thiocyanate level could not be analyzed due to an “interfering substance”. Hydroxocobalamin is an effective antidote. …450Cite
Jeyaprakash A, Hoy MA.Exp Appl Acarol. 2010 Oct;52(2):131-40. doi: 10.1007/s10493-010-9357-9. Epub 2010 Mar 24.PMID: 20333447451Cite
Lii CK, Liu KL, Cheng YP, Lin AH, Chen HW, Tsai CW.J Nutr. 2010 May;140(5):885-92. doi: 10.3945/jn.110.121418. Epub 2010 Mar 17.PMID: 20237067 Free article.452Cite
Effects of bovine milk lactoperoxidase system on some bacteria.
Cankaya M, Sişecioğlu M, Bariş O, Güllüce M, Ozdemir H.Prikl Biokhim Mikrobiol. 2010 Jan-Feb;46(1):64-8.PMID: 20198919
Bovine LPO showed high antibacterial activity in 100 mM thiocyanate-100 mM H2O2 medium for some bacteria (Brevibacillus centrosaurus, B. choshinensis, B. lyticum, Cedecea davisae, Chryseobacterium indoltheticum, Clavibacter michiganense pv. insidiosum, Kocuria erythromyxa, …453Cite
Mishin V, Gray JP, Heck DE, Laskin DL, Laskin JD.Free Radic Biol Med. 2010 Jun 1;48(11):1485-91. doi: 10.1016/j.freeradbiomed.2010.02.030. Epub 2010 Feb 25.PMID: 20188819 Free PMC article.
This assay is 20 times more sensitive (LLD=5.0pmol/assay and LLQ=30pmol/assay) than the standard ferrous thiocyanate assay for detection of hydrogen peroxide. We found low, but detectable, spontaneous generation of hydrogen peroxide by recombinant human NADPH-cytochrome P4 …454Cite
Arezi B, McCarthy M, Hogrefe H.Anal Biochem. 2010 May 15;400(2):301-3. doi: 10.1016/j.ab.2010.01.024. Epub 2010 Jan 25.PMID: 20100452
IC(50) values were determined for potential RNA contaminants, including guanidine thiocyanate, ethanol, formamide, ethylenediaminetetraacetic acid (EDTA), and plant-related acidic polysaccharides. …455Cite
Rosu T, Pahontu E, Pasculescu S, Georgescu R, Stanica N, Curaj A, Popescu A, Leabu M.Eur J Med Chem. 2010 Apr;45(4):1627-34. doi: 10.1016/j.ejmech.2009.12.015. Epub 2010 Jan 22.PMID: 20096975
Also, if copper(II) acetate, copper(II) nitrate, copper(II) chloride and copper(II) thiocyanate were used, the ligands coordinated in a mononegative bidentate fashion. If copper(II) sulfate was used, the ligands coordinated in a neutral bidentate fashion. …456Cite
Shin DH, Park HM, Jung KA, Choi HG, Kim JA, Kim DD, Kim SG, Kang KW, Ku SK, Kensler TW, Kwak MK.Free Radic Biol Med. 2010 Apr 15;48(8):1051-63. doi: 10.1016/j.freeradbiomed.2010.01.021. Epub 2010 Jan 22.PMID: 20096777 Free PMC article.457Cite
Xulu BA, Ashby MT.Biochemistry. 2010 Mar 9;49(9):2068-74. doi: 10.1021/bi902089w.PMID: 20085320 Free PMC article.
Thiocyanate reacts noncatalytically with myeloperoxidase-derived HOCl to produce hypothiocyanite (OSCN(-)), thereby potentially limiting the propensity of HOCl to inflict host tissue damage that can lead to inflammatory diseases. …458Cite
Wiśniewski A, Pekala K, Orlik M.J Phys Chem A. 2010 Jan 14;114(1):183-90. doi: 10.1021/jp907558n.PMID: 20055515459Cite
Candida albicans biofilm on titanium: effect of peroxidase precoating.
Ahariz M, Courtois P.Med Devices (Auckl). 2010;3:33-40. doi: 10.2147/mder.s11724. Epub 2010 Aug 4.PMID: 22915919 Free PMC article.
The present study aimed to document Candida albicans biofilm development on titanium and its modulation by a peroxidase-precoated material which can generate antimicrobials, such as hypoiodite or hypothiocyanite, from hydrogen peroxide, iodide, or thiocyanate. …Ho …460Cite
Wang TT, Zeng GC, Li XC, Zeng HP.Chem Biol Drug Des. 2010 Feb;75(2):214-22. doi: 10.1111/j.1747-0285.2009.00925.x. Epub 2009 Dec 17.PMID: 20028394
The activity against lipid peroxidation was determined using ammonium thiocyanate method. The results revealed that introduction of electron-donating groups at 2nd position decreased the antioxidant activities of 8-hydroxyquinoline derivatives. …461Cite
Extraction of high quality RNA from polysaccharide matrices using cetyltrimethylammonium bromide.
Wang L, Stegemann JP.Biomaterials. 2010 Mar;31(7):1612-8. doi: 10.1016/j.biomaterials.2009.11.024. Epub 2009 Dec 3.PMID: 19962190 Free PMC article.
CTAB extraction was compared to conventional guanidinium thiocyanate-based methods for RNA isolation by assessing RNA yield, purity (A260/A280 and A260/A230) and integrity (28S/18S and RIN). …For pure collagen matrices, the CTAB method was comparable or better than guani …462Cite
Environmental pollutants and the thyroid.
Pearce EN, Braverman LE.Best Pract Res Clin Endocrinol Metab. 2009 Dec;23(6):801-13. doi: 10.1016/j.beem.2009.06.003.PMID: 19942155 Review.
Foetuses and infants are most vulnerable to these effects because they need thyroid hormone for normal neurodevelopment. Perchlorate, thiocyanate and nitrate are all competitive inhibitors of the sodium/iodine symporter (NIS) in pharmacologic doses, but their effects on hu …463Cite
Xu Y, Szép S, Lu Z.Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20515-9. doi: 10.1073/pnas.0911412106. Epub 2009 Nov 16.PMID: 19918082 Free PMC article.
Although commonly known as a Cl(-) channel, CFTR also conducts thiocyanate (SCN(-)) ions, important because, in several ways, they can limit potentially harmful accumulations of hydrogen peroxide (H(2)O(2)) and hypochlorite (OCl(-)). …464Cite
Dual oxidases and hydrogen peroxide in a complex dialogue between host mucosae and bacteria.
Allaoui A, Botteaux A, Dumont JE, Hoste C, De Deken X.Trends Mol Med. 2009 Dec;15(12):571-9. doi: 10.1016/j.molmed.2009.10.003. Epub 2009 Nov 11.PMID: 19913458
The recent discovery of dual oxidase (DUOX)-dependent H(2)O(2) generation associated with peroxidase and thiocyanate secretion at the apex of mucosal cells has been similarly interpreted as a killing mechanism. …465Cite
Nagy P, Jameson GN, Winterbourn CC.Chem Res Toxicol. 2009 Nov;22(11):1833-40. doi: 10.1021/tx900249d.PMID: 19821602466Cite
Residual goiter in Semirom; iodine status and thiocyanate overload do not play a role.
Keshteli AH, Hashemipour M, Amini M, Siavash M, Aminorroaya A, Rezvanian H, Kachuei A, Kelishadi R.J Trop Pediatr. 2010 Jun;56(3):216-7. doi: 10.1093/tropej/fmp096. Epub 2009 Oct 1.PMID: 19797397
This study was performed to investigate the role of thiocyanate overload in the etiology of endemic goiter in schoolchildren of Semirom, Iran. …Urinary iodine concentration (UIC) and urinary thiocyanate (USCN) were measured in a group of these children. The median …467Cite
Tarozzi A, Morroni F, Merlicco A, Hrelia S, Angeloni C, Cantelli-Forti G, Hrelia P.J Neurochem. 2009 Dec;111(5):1161-71. doi: 10.1111/j.1471-4159.2009.06394.x. Epub 2009 Sep 22.PMID: 19780897 Free article.
A strategy to prevent the OS of dopaminergic cells in the SN may be the use of chemopreventive agents as inducers of endogenous GSH, antioxidant and phase 2 enzymes. In this study, we demonstrated that treatment of the dopaminergic-like neuroblastoma SH-SY5Y cell line with …468Cite
Extracellular redox status regulates Nrf2 activation through mitochondrial reactive oxygen species.
Imhoff BR, Hansen JM.Biochem J. 2009 Dec 10;424(3):491-500. doi: 10.1042/BJ20091286.PMID: 19778293469Cite
Völzke H, Bornhorst A, Rimmbach C, Petersenn H, Geissler I, Nauck M, Wallaschofski H, Kroemer HK, Rosskopf D.Thyroid. 2009 Oct;19(10):1115-9. doi: 10.1089/thy.2009.0134.PMID: 19772422
Data from 3428 subjects (1800 men and 1628 women) were analyzed for an association of the GNB3 genotype with TSH, free triiodothyronine and thyroxine levels, urine iodine and thiocyanate excretion, and thyroid ultrasound morphology including thyroid volume, presence of goi …470Cite
Takahama U, Imamura H, Hirota S.Eur J Oral Sci. 2009 Oct;117(5):555-62. doi: 10.1111/j.1600-0722.2009.00671.x.PMID: 19758252
Thus, the objectives of the present study were to estimate the concentrations of HPA, nitrated HPA [4-hydroxy-3-nitrophenylacetic acid (NO(2)HPA)], nitrite, and thiocyanate (SCN(-)) in saliva from 73 patients with periodontal diseases and to elucidate the conditions necess …471Cite
Jyoti S, Shashikiran ND, Reddy VV.J Clin Pediatr Dent. 2009 Summer;33(4):299-303. doi: 10.17796/jcpd.33.4.83331867x68w120n.PMID: 19725235 Free article. Clinical Trial.
Salivary samples were analyzed for mutans streptococci (MS) and Lactobacilli, and for the levels of Thiocyanate ions. RESULTS: Showed significant increase in the levels of Thiocyanate ion in saliva during experimental period. …This increased concentration of th …472Cite
Lemma K, Ashby MT.Chem Res Toxicol. 2009 Sep;22(9):1622-8. doi: 10.1021/tx900212r.PMID: 19705807
In the oral cavity, salivary peroxidase and MPO catalyze the oxidation of the pseudohalide thiocyanate (SCN(-)) by hydrogen peroxide to produce the antimicrobial hypothiocyanite (OSCN(-)). …473Cite
Oxidative epithelial host defense is regulated by infectious and inflammatory stimuli.
Gattas MV, Forteza R, Fragoso MA, Fregien N, Salas P, Salathe M, Conner GE.Free Radic Biol Med. 2009 Nov 15;47(10):1450-8. doi: 10.1016/j.freeradbiomed.2009.08.017. Epub 2009 Aug 22.PMID: 19703552 Free PMC article.
Epithelia express oxidative antimicrobial protection that uses lactoperoxidase (LPO), hydrogen peroxide (H(2)O(2)), and thiocyanate to generate the reactive hypothiocyanite. …474Cite
Influence of a model human defensive peroxidase system on oral streptococcal antagonism.
Ashby MT, Kreth J, Soundarajan M, Sivuilu LS.Microbiology (Reading). 2009 Nov;155(Pt 11):3691-3700. doi: 10.1099/mic.0.031310-0. Epub 2009 Aug 14.PMID: 19684069 Free PMC article.475Cite
Crane MS, Howie AF, Arthur JR, Nicol F, Crosley LK, Beckett GJ.Biochim Biophys Acta. 2009 Oct;1790(10):1191-7. doi: 10.1016/j.bbagen.2009.07.001. Epub 2009 Jul 10.PMID: 19595745476Cite
Role of iodine, selenium and other micronutrients in thyroid function and disorders.
Triggiani V, Tafaro E, Giagulli VA, Sabbà C, Resta F, Licchelli B, Guastamacchia E.Endocr Metab Immune Disord Drug Targets. 2009 Sep;9(3):277-94. doi: 10.2174/187153009789044392. Epub 2009 Sep 1.PMID: 19594417 Review.
Substances introduced with food, such as thiocyanate and isoflavones or certain herbal preparations, can interfere with micronutrients and influence thyroid function. …477Cite
Welk A, Meller Ch, Schubert R, Schwahn Ch, Kramer A, Below H.BMC Microbiol. 2009 Jul 9;9:134. doi: 10.1186/1471-2180-9-134.PMID: 19589149 Free PMC article.
BACKGROUND: The positive antimicrobial effects of increasing concentrations of thiocyanate (SCN-) and H2O2 on the human peroxidase defence system are well known. …Thus, the mixtures of 2.0% (w/v; 0.34 M) thiocyanate and 0.4% (w/v; 0.12 M) hydrogen peroxide …478Cite
Chandra AK, Bhattacharjee A, Malik T, Ghosh S.J Pediatr Endocrinol Metab. 2009 Apr;22(4):317-25. doi: 10.1515/jpem.2009.22.4.317.PMID: 19554805
METHODS: Goiter survey among 1,862 school children, aged 6-12 years, of both sexes, and analysis of iodine (I) and thiocyanate (SCN) in 240 urine samples, and iodine content in 210 edible salt samples collected from the selected study areas. …479Cite
Singh A, Sharma ML, Singh J.Nat Prod Res. 2009;23(11):1029-34. doi: 10.1080/14786410802587073.PMID: 19521918480Cite
[Sulforaphane (1-isothiocyanato-4-(methylsulfinyl)-butane) content in cruciferous vegetables].
Campas-Baypoli ON, Bueno-Solano C, Martínez-Ibarra DM, Camacho-Gil F, Villa-Lerma AG, Rodríguez-Núñez JR, Lóez-Cervantes J, Sánchez-Machado DI.Arch Latinoam Nutr. 2009 Mar;59(1):95-100.PMID: 19480351 Spanish.
Sulforaphane is an isothiocyanate which has antimicrobial and anticarcinogenic properties, this compound is found in a wide variety of plants from genus Brassica oleracea, being the most important broccoli and cabbage. …481Cite
Peroxidative metabolism of beta2-agonists salbutamol and fenoterol and their analogues.
Reszka KJ, McGraw DW, Britigan BE.Chem Res Toxicol. 2009 Jun;22(6):1137-50. doi: 10.1021/tx900071f.PMID: 19462961 Free PMC article.
We show that in the presence of hydrogen peroxide, both myeloperoxidase, secreted by activated neutrophils present in inflamed airways, and lactoperoxidase, which is naturally present in the respiratory system, catalyze oxidation of these beta(2)-agonists. Azide, cyanide, thio …482Cite
Kim YM, Park D, Lee DS, Jung KA, Park JM.Bioresour Technol. 2009 Oct;100(19):4340-7. doi: 10.1016/j.biortech.2009.04.014. Epub 2009 May 7.PMID: 19427199
A full-scale pre-denitrification process treating cokes wastewater containing toxic compounds such as phenols, cyanides and thiocyanate has shown good performance in carbon and nitrogen removal. However, field operators have been having trouble with its instability without …483Cite
Garcés-Sanchez G, Wilderer PA, Munch JC, Horn H, Lebuhn M.Water Res. 2009 Jun;43(10):2669-78. doi: 10.1016/j.watres.2009.03.019. Epub 2009 Mar 21.PMID: 19401258484Cite
Whitehouse MW, Jones M.Inflamm Res. 2009 Oct;58(10):693-704. doi: 10.1007/s00011-009-0038-2. Epub 2009 Apr 10.PMID: 19360377
METHODS: Rats (>300) received low levels of sodium/potassium thiocyanate (10 or 25 mmol/l) in their drinking water to raise their blood thiocyanate levels, mimicking the elevated levels of blood, salivary and urinary thiocyanate found in smokers. …Iodide …485Cite
Taga I, Oumbe VA, Johns R, Zaidi MA, Yonkeu JN, Altosaar I.Afr Health Sci. 2008 Sep;8(3):180-5.PMID: 19357747 Free PMC article.
BACKGROUND: Hypothyroidism in utero leading to mental retardation is highly prevalent in developing countries where iodine deficiency and thiocyanate overload are combined. OBJECTIVE: To explore prevalence of IDD in Bamougoum, a mountain region of western Cameroon, by stud …486Cite
Antioxidant and antimicrobial activities of bitter and sweet apricot (Prunus armeniaca L.) kernels.
Yiğit D, Yiğit N, Mavi A.Braz J Med Biol Res. 2009 Apr;42(4):346-52. doi: 10.1590/s0100-879×2009000400006.PMID: 19330262 Free article.
The present study describes the in vitro antimicrobial and antioxidant activity of methanol and water extracts of sweet and bitter apricot (Prunus armeniaca L.) kernels. The antioxidant properties of apricot kernels were evaluated by determining radical scavenging power, l …487Cite
Kleiner CM, Horst L, Würtele C, Wende R, Schreiner PR.Org Biomol Chem. 2009 Apr 7;7(7):1397-403. doi: 10.1039/b820232j. Epub 2009 Feb 25.PMID: 19300825
Herein we shed light on the mechanism of the reaction of epoxides with ammonium thiocyanate to give the corresponding thiiranes in water, and we present a computational mechanistic model for this highly useful reaction….488Cite
[Kinetics study on reaction of chlorine dioxide and thiocyanide in water].
Hu C, Bi X, Zhang L, Li H.Wei Sheng Yan Jiu. 2009 Jan;38(1):22-3, 35.PMID: 19267068 Chinese.489Cite
Iodine deficiency in children 7-19 years old in Eastern Province of Cameroon.
Taga I, Agbor GA, Djountsop S, Moshin ZA, Oumbé VA, Altosaar I, Ngogang JY.Trop Med Int Health. 2009 Mar;14(3):311-5. doi: 10.1111/j.1365-3156.2009.02224.x. Epub 2009 Jan 21.PMID: 19207172 Free article.
OBJECTIVE: To determine the prevalence of iodine deficiency in children in Eastern Province, Cameroon. METHOD: Urinary iodine (I) and thiocyanate (SCN) excretion levels were assessed in 158 children (62 boys and 96 girls) aged 7-19 years. …490Cite
Takeda T, Sonoyama T, Takayama SJ, Mita H, Yamamoto Y, Sambongi Y.Biosci Biotechnol Biochem. 2009 Feb;73(2):366-71. doi: 10.1271/bbb.80607. Epub 2009 Feb 7.PMID: 19202290 Free article.
The stability of the oxidized and reduced forms of three homologous cytochromes c from two thermophiles and one mesophile was systematically monitored by means of Soret absorption measurements in the presence of various concentrations of a denaturant, guanidine thiocyanate …491Cite
Prachasilchai W, Sonoda H, Yokota-Ikeda N, Ito K, Kudo T, Imaizumi K, Ikeda M.J Pharmacol Sci. 2009 Feb;109(2):311-4. doi: 10.1254/jphs.08272sc. Epub 2009 Jan 29.PMID: 19179808 Free article.492Cite
Chandra AK, Singh LH, Debnath A, Tripathy S, Khanam J.Indian J Med Res. 2008 Nov;128(5):601-5.PMID: 19179679 Free article.
A total of 160 urine samples were collected and analyzed to measure urinary iodine and thiocyanate levels. Iodine content was measured in 140 salt samples and 16 drinking water samples. RESULTS: Overall goitre prevalence was about 30 per cent (grade 1-24.7%; grade 2-5.3%) …493Cite
Ohira S, Kirk AB, Dyke JV, Dasgupta PK.Environ Sci Technol. 2008 Dec 15;42(24):9419-23. doi: 10.1021/es8020952.PMID: 19174925
Iodine and selenium were determined with induction coupled plasma-mass spectrometry (ICP-MS). Perchlorate and thiocyanate were measured with ion chromatography (IC)-isotope dilution tandem mass spectrometry (MS/MS). …Creatinine adjustment for estimation of 24 h excretion …494Cite
Lamani RS, Shetty NS, Kamble RR, Khazi IA.Eur J Med Chem. 2009 Jul;44(7):2828-33. doi: 10.1016/j.ejmech.2008.12.019. Epub 2008 Dec 25.PMID: 19168262
Thiocyanato derivatives (6a-f) were obtained by treating the imidazothiadiazole 3 with bromine and potassium thiocyanate in glacial acetic acid at room temperature. The structures of the newly synthesized compounds were confirmed by IR, NMR, mass and elemental analysis. .. …495Cite
Singh AK, Singh N, Sharma S, Shin K, Takase M, Kaur P, Srinivasan A, Singh TP.Biophys J. 2009 Jan;96(2):646-54. doi: 10.1016/j.bpj.2008.09.019.PMID: 19167310 Free PMC article.
In the presence of hydrogen peroxide, it preferentially converts thiocyanate ion into a toxic hypothiocyanate ion. Samples of bovine lactoperoxidase containing thiocyanate (SCN(-)) and hypothiocyanate (OSCN(-)) ions were purified and crystallized. …496Cite
Iodine nutritional status of children on the island of Tanna, Republic of Vanuatu.
Li M, McKelleher N, Moses T, Mark J, Byth K, Ma G, Eastman CJ.Public Health Nutr. 2009 Sep;12(9):1512-8. doi: 10.1017/S1368980008004497. Epub 2009 Jan 20.PMID: 19152716
A food consumption frequency survey was carried out, particularly in relation to salt, iodine-rich foods and foods that containing thiocyanate, a potentially goitrogenic substance. Urinary thiocyanate levels were also measured. …There was a highly statistically si …497Cite
Antioxidant and antiinflammatory activity of pine pollen extract in vitro.
Lee KH, Kim AJ, Choi EM.Phytother Res. 2009 Jan;23(1):41-8. doi: 10.1002/ptr.2525.PMID: 19107823
It was observed also that the antioxidant activity, measured by the ferric thiocyanate method, increased with the addition of PPE to the linoleic acid emulsion system. …498Cite
Bai Y, Shang WL, Dang DB, Sun JD, Gao H.Spectrochim Acta A Mol Biomol Spectrosc. 2009 Mar;72(2):407-11. doi: 10.1016/j.saa.2008.10.033. Epub 2008 Nov 6.PMID: 19062330499Cite
Taga I, Oumbe VA, Johns R, Zaidi MA, Yonkeu NJ, Altosaar I.Afr Health Sci. 2008 Dec;8(4):227-33.PMID: 20589129 Free PMC article.
OBJECTIVES: Hypothyroidism in utero leading to mental retardation is highly prevalent and recurrent in developing countries where iodine deficiency and thiocyanate overload are combined. So, to explore and identify human population’s risks for developing iodine deficiency …500Cite
Intake of iodine and perchlorate and excretion in human milk.
Dasgupta PK, Kirk AB, Dyke JV, Ohira S.Environ Sci Technol. 2008 Nov 1;42(21):8115-21. doi: 10.1021/es801549w.PMID: 19031911
Perchlorate, thiocyanate, and iodine excretion in urine and milk of 13 breastfeeding women was investigated and the results were interpreted by a model of parallel/competitive transport of these species bythe sodium iodide symporter. …The fraction of the total excretion …501Cite
Anwar-Mohamed A, El-Kadi AO.Cancer Lett. 2009 Mar 8;275(1):93-101. doi: 10.1016/j.canlet.2008.10.003. Epub 2008 Nov 13.PMID: 19013013
Recent reports have proposed that some naturally occurring phytochemicals can function as anticancer agents mainly through inducing phase II drug detoxification enzymes. Of these phytochemicals, isothiocyanates sulforaphane (SUL), present in broccoli, is by far the most ex …502Cite
Wang X, Ashby MT.Chem Res Toxicol. 2008 Nov;21(11):2120-6. doi: 10.1021/tx800195n.PMID: 18942795
Hypothiocyanite (OSCN(-)) is a putative antimicrobial that is produced by defensive human peroxidases, including salivary peroxidase, lactoperoxidase, eosinophil peroxidase, and myeloperoxidase. The reaction of OSCN(-) with cysteine-derived sulfhydryl groups is believed to …503Cite
Hypobromous acid and bromamine production by neutrophils and modulation by superoxide.
Chapman AL, Skaff O, Senthilmohan R, Kettle AJ, Davies MJ.Biochem J. 2009 Feb 1;417(3):773-81. doi: 10.1042/BJ20071563.PMID: 18851713
MPO (myeloperoxidase) catalyses the oxidation of chloride, bromide and thiocyanate to their respective hypohalous acids. We have investigated the generation of HOBr by human neutrophils in the presence of physiological concentrations of chloride and bromide. …504Cite
Inorganic chemistry of defensive peroxidases in the human oral cavity.
Ashby MT.J Dent Res. 2008 Oct;87(10):900-14. doi: 10.1177/154405910808701003.PMID: 18809743 Review.
With hydrogen peroxide (H(2)O(2)) as an oxidant, the defensive peroxidases use inorganic ions to produce antimicrobials that are generally more effective than H(2)O(2) itself. The concentrations of the inorganic substrates are different in saliva vs. gingival crevicular fl …505Cite
Rada B, Lekstrom K, Damian S, Dupuy C, Leto TL.J Immunol. 2008 Oct 1;181(7):4883-93. doi: 10.4049/jimmunol.181.7.4883.PMID: 18802092 Free PMC article.
The dual oxidase-thiocyanate-lactoperoxidase (Duox/SCN(-)/LPO) system generates the microbicidal oxidant hypothiocyanite in the airway surface liquid by using LPO, thiocyanate, and Duox-derived hydrogen peroxide released from the apical surface of the airway epithel …506Cite
1,10-Phenanthroline-H2O2-KSCN-CuSO4-NaOH oscillating chemiluminescence system.
Sorouraddin MH, Iranifam M.Luminescence. 2009 Mar-Apr;24(2):115-22. doi: 10.1002/bio.1084.PMID: 18785618507Cite
Ingermann RL, Holcomb M, Zuccarelli MD, Kanuga MK, Cloud JG.Comp Biochem Physiol A Mol Integr Physiol. 2008 Dec;151(4):651-6. doi: 10.1016/j.cbpa.2008.08.005. Epub 2008 Aug 12.PMID: 18760373
Sperm incubated in an immobilization buffer (SI) at low pH ( approximately 7.1-7.2) become motile when diluted with activating medium (AM) at high ( approximately 8.5) but not low pH. Based on this observation, various agents were tested to determine whether the onset of s …508Cite
Inokuchi Y, Nakajima Y, Shimazawa M, Kurita T, Kubo M, Saito A, Sajiki H, Kudo T, Aihara M, Imaizumi K, Araie M, Hara H.Invest Ophthalmol Vis Sci. 2009 Jan;50(1):334-44. doi: 10.1167/iovs.08-2123. Epub 2008 Aug 29.PMID: 18757512509Cite
Singh G, Kapoor IP, Singh P, de Heluani CS, de Lampasona MP, Catalan CA.Food Chem Toxicol. 2008 Oct;46(10):3295-302. doi: 10.1016/j.fct.2008.07.017. Epub 2008 Jul 29.PMID: 18706468
The antioxidant activity of essential oil and oleoresins were evaluated against mustard oil by peroxide, anisidine, thiobarbituric acid (TBA), ferric thiocyanate (FTC) and 2,2′-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging methods. They were found to be better antiox …510Cite
Sakai S, Nonobe E, Satow T, Imakawa K, Nagaoka K.J Dairy Res. 2008 Aug;75(3):335-9. doi: 10.1017/S0022029908003300.PMID: 18680618
In this study, we present parameters for evaluating the lactoperoxidase/H2O2/thiocyanate antibacterial defence system in bovine milk….511Cite
Effect of humic substances on the Fenton treatment of wastewater at acidic and neutral pH.
Lipczynska-Kochany E, Kochany J.Chemosphere. 2008 Oct;73(5):745-50. doi: 10.1016/j.chemosphere.2008.06.028.PMID: 18657846
At pH 3.5, humate had no effect on the removal of arsenic, thiocyanate and cyanide, but the removal of all organic compounds (phenol, 2,4-dimethylphenol, benzene, toluene, o-xylene, m- & p-xylene and dichloromethane) was significantly inhibited. …512Cite
Rojo AI, Rada P, Egea J, Rosa AO, López MG, Cuadrado A.Mol Cell Neurosci. 2008 Sep;39(1):125-32. doi: 10.1016/j.mcn.2008.06.007. Epub 2008 Jun 20.PMID: 18619545513Cite
Colostrum iodine and perchlorate concentrations in Boston-area women: a cross-sectional study.
Leung AM, Pearce EN, Hamilton T, He X, Pino S, Merewood A, Braverman LE.Clin Endocrinol (Oxf). 2009 Feb;70(2):326-30. doi: 10.1111/j.1365-2265.2008.03330.x. Epub 2008 Jun 27.PMID: 18616704
OBJECTIVE: To measure levels of colostrum iodine, which has not been previously measured, and perchlorate and cotinine (a surrogate for thiocyanate derived from cigarette smoke) in women up to 60 h postpartum. Perchlorate and thiocyanate are environmental inhibitors …514Cite
Mastrangelo G, Marcer G, Cegolon L, Buja A, Fadda E, Scoizzato L, Pavanello S.Med Hypotheses. 2008 Oct;71(4):551-63. doi: 10.1016/j.mehy.2008.05.016. Epub 2008 Jul 9.PMID: 18614293 Free article.
The hypothiocyanite anion (OSCN-) is generated in vivo by the reaction of thiocyanate with hydrogen peroxide catalyzed by lactoperoxidase. OSCN- is an antimicrobial oxidizing agent that prevents growth of bacteria, fungi, and viruses. …515Cite
Xu Y, Pehrsson PE, Chen L, Zhao W.J Am Chem Soc. 2008 Aug 6;130(31):10054-5. doi: 10.1021/ja802743h. Epub 2008 Jul 9.PMID: 18611008
At the later stage, the suppressed spectral intensity is recovered overtime. The thiocyanate ions may work as a mediator being able to control the reaction rate as well as the tunable properties of the reaction. The tunable redox reaction of SWNTs and H2O2 mediated by t …516Cite
Suzuki Y, Mae T, Makino A.Biosci Biotechnol Biochem. 2008 Jul;72(7):1951-3. doi: 10.1271/bbb.80084. Epub 2008 Jul 7.PMID: 18603812 Free article.
High-quality total RNA was extracted using a cethyltrimethylammonium bromide-containing buffer followed by an acid guanidium thiocyanate-phenol-chloroform treatment from recalcitrant plant tissues such as tree leaves (pine, Norway spruce, ginkgo, Japanese cedar, rose), flo …517Cite
Chandra AK, Bhattacharjee A, Malik T, Ghosh S.Indian Pediatr. 2008 Jun;45(6):469-74.PMID: 18599931 Free article.
METHODS: Clinical goiter survey was conducted in 1663 school-aged children from both sexes (6-12 yrs), along with the biochemical analysis of iodine (I) and thiocyanate (SCN) in 200 urine samples, iodine content in 175 edible salt samples and 20 water samples collected fro …518Cite
Fweja LW, Lewis MJ, Grandison AS.J Dairy Sci. 2008 Jul;91(7):2566-74. doi: 10.3168/jds.2007-0322.PMID: 18565914 Free article.
Lactoperoxidase (LP) exerts antimicrobial effects in combination with H(2)O(2) and either thiocyanate (SCN(-)) or a halide (e.g., I(-)). …519Cite
Perchlorate in the feed-dairy continuum of the southwestern United States.
Sanchez CA, Blount BC, Valentin-Blasini L, Lesch SM, Krieger RI.J Agric Food Chem. 2008 Jul 9;56(13):5443-50. doi: 10.1021/jf0733923. Epub 2008 Jun 13.PMID: 18553887520Cite
Antioxidant and radical scavenging properties of curcumin.
Ak T, Gülçin I.Chem Biol Interact. 2008 Jul 10;174(1):27-37. doi: 10.1016/j.cbi.2008.05.003. Epub 2008 May 7.PMID: 18547552
In the present paper, we determined the antioxidant activity of curcumin by employing various in vitro antioxidant assays such as 1,1-diphenyl-2-picryl-hydrazyl free radical (DPPH*) scavenging, 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activi …521Cite
del V Cano M, Reyes JM, Park CY, Gao X, Mori K, Chuck RS, Gehlbach PL.Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2606-12. doi: 10.1167/iovs.07-0960.PMID: 18515589522Cite
Kim YM, Park D, Jeon CO, Lee DS, Park JM.Bioresour Technol. 2008 Dec;99(18):8824-32. doi: 10.1016/j.biortech.2008.04.050. Epub 2008 Jun 2.PMID: 18514513
A lab-scale serial anoxic-aerobic reactor for the pre-denitrification process was continuously operated to efficiently and economically treat actual cokes wastewater containing various pollutants, such as phenol, ammonia, thiocyanate and cyanide compounds. The biodegradati …523Cite
Sheng H, Ye BC.Appl Biochem Biotechnol. 2009 Jan;152(1):54-65. doi: 10.1007/s12010-008-8245-9. Epub 2008 May 20.PMID: 18491234524Cite
Johansson NL, Pavia CS, Chiao JW.Planta Med. 2008 Jun;74(7):747-50. doi: 10.1055/s-2008-1074520. Epub 2008 May 16.PMID: 18484523
The broad-spectrum antibiotic, ceftriaxone (CTX), was used as a positive control for antimicrobial inhibition. It was found that 23 out of 28 different microbial species were inhibited by SFN with a minimal inhibitory concentration (MIC) ranging from 1-4 microg/mL. …525Cite
Oscillating chemiluminescence with thiosemicarbazide in a batch reactor.
Sorouraddin MH, Iranifam M.Luminescence. 2008 Sep-Oct;23(5):303-8. doi: 10.1002/bio.1034.PMID: 18452144526Cite
Perchlorate: overview of risks and regulation.
Charnley G.Food Chem Toxicol. 2008 Jul;46(7):2307-15. doi: 10.1016/j.fct.2008.03.006. Epub 2008 Mar 10.PMID: 18440116 Review.
For example, studies associating perchlorate with thyroid effects at low exposures did not control for anti-thyroid agents with modes of action that differ from that of perchlorate, such as some organochlorines. …However, potential perchlorate risks are unlikely to be di …527Cite
Preparation of RNA from tissues and cells.
Ribaudo R, Gilman M, Kingston RE, Chomczynski P, Sacchi N.Curr Protoc Neurosci. 2001 May;Appendix 1:Appendix 1I. doi: 10.1002/0471142301.nsa01is07.PMID: 18428440
The nuclei and hence the bulk of the cellular DNA are then removed with a simple brief centrifugation. A guanidinium thiocyanate protocol describes the separation of RNA from other cellular macromolecules in a guanidinium lysate using a CsCl step gradient. …528Cite
Oida Y, Izuta H, Oyagi A, Shimazawa M, Kudo T, Imaizumi K, Hara H.Brain Res. 2008 May 7;1208:217-24. doi: 10.1016/j.brainres.2008.02.068. Epub 2008 Mar 4.PMID: 18395193529Cite
Schwab M, Reynders V, Loitsch S, Steinhilber D, Schröder O, Stein J.Immunology. 2008 Oct;125(2):241-51. doi: 10.1111/j.1365-2567.2008.02834.x. Epub 2008 Mar 27.PMID: 18373608 Free PMC article.
Antimicrobial peptides like human beta-defensin-2 (HBD-2) play an important role in the innate immune system protecting the intestinal mucosa against bacterial invasion. …The data clearly demonstrate for the first time that the dietary HDAC inhibitor SFN is able to induc …530Cite
Kim HJ, Barajas B, Wang M, Nel AE.J Allergy Clin Immunol. 2008 May;121(5):1255-1261.e7. doi: 10.1016/j.jaci.2008.01.016. Epub 2008 Mar 5.PMID: 18325578 Free PMC article.531Cite
Shin K, Horigome A, Wakabayashi H, Yamauchi K, Yaeshima T, Iwatsuki K.J Breath Res. 2008 Mar;2(1):017014. doi: 10.1088/1752-7155/2/1/017014. Epub 2008 Mar 7.PMID: 21386158
The antimicrobial activity of a composition containing bovine lactoperoxidase (LPO), glucose oxidase, glucose and buffer salts was tested against oral bacteria in vitro. …Suspension of the composition in filter-sterilized saliva or phosphate-buffered saline containing so …532Cite
Mechanism of inhibition of catalase by nitro and nitroso compounds.
Titov VY, Petrenko YM, Vanin AF.Biochemistry (Mosc). 2008 Jan;73(1):92-6. doi: 10.1134/s0006297908010148.PMID: 18294136
The efficiency of inhibition sharply (by several orders in concentration of these agents) increases in the presence of chloride, bromide, and thiocyanate. The nitro compounds tested–nitroarginine, nitroglycerol, nitrophenol, and furazolidone–gained the same inhibi …533Cite
Low cost in-house PCR for the routine diagnosis of extra-pulmonary tuberculosis.
Magana-Arachchi D, Perera J, Gamage S, Chandrasekharan V.Int J Tuberc Lung Dis. 2008 Mar;12(3):275-80.PMID: 18284832
This study also compared the efficacy of a standard phenol-chloroform (PC) extraction procedure and the guanidine thiocyanate with diatomaceous silica (GTCS) method of DNA extraction and purification. A subsample of patients was used for the validation of results based on …534Cite
Güllçin I, Daştan A.J Enzyme Inhib Med Chem. 2007 Dec;22(6):685-95. doi: 10.1080/14756360601164903.PMID: 18237020 Free article.
Their antioxidant capacity and radical scavenging activity were examined using different in vitro methodologies such as 1,1-diphenyl-2-picryl-hydrazyl (DPPH*) free radical scavenging, 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, total …535Cite
Tokunaga S, Kanayama A, Miyamoto Y.Inflamm Res. 2007 Nov;56(11):479-86. doi: 10.1007/s00011-007-7016-3.PMID: 18224289536Cite
Samadi-Maybodi A, Akhoondi R.Luminescence. 2008 Jan-Feb;23(1):42-8. doi: 10.1002/bio.1015.PMID: 18175293537Cite
Ding LW, Sun QY, Wang ZY, Sun YB, Xu ZF.Anal Biochem. 2008 Mar 15;374(2):426-8. doi: 10.1016/j.ab.2007.11.030. Epub 2007 Nov 28.PMID: 18166144
The most commonly used protocol of the RNA isolation, the guanidine thiocyanate method, was unsuitable for recalcitrant plant tissues containing a large amount of storage proteins and secondary metabolites. …Based on this observation, an efficient, inexpensive, and highl …538Cite
Shavali S, Sens DA.Toxicol Sci. 2008 Apr;102(2):254-61. doi: 10.1093/toxsci/kfm302. Epub 2007 Dec 13.PMID: 18079140539Cite
Reactive sulfur species: hydrolysis of hypothiocyanite to give thiocarbamate-S-oxide.
Nagy P, Wang X, Lemma K, Ashby MT.J Am Chem Soc. 2007 Dec 26;129(51):15756-7. doi: 10.1021/ja0770532. Epub 2007 Dec 6.PMID: 18052381540Cite
Demir Y, Nadaroğlu H, Demir N.Indian J Biochem Biophys. 2007 Aug;44(4):252-6.PMID: 17970284541Cite
Criss-cross cycloadditions on ketazines derived from alicyclic ketones.
Verner J, Potácek M.Molecules. 2006 Jan 31;11(1):34-42. doi: 10.3390/11010034.PMID: 17962743 Free PMC article.
They react with potassium cyanate and ammonium thiocyanate in the presence of acetic acid to form spirocyclic perhydro[1,2,4]triazolo[1,2-alpha][1,2,4]triazole-1,5-diones and perhydro[1,2,4]triazolo[1,2-alpha][1,2,4]triazole-1,5-dithiones, respectively, in relatively high …542Cite
Treatment of coke wastewater in a sequential batch reactor (SBR) at pilot plant scale.
Marañón E, Vázquez I, Rodríguez J, Castrillón L, Fernández Y, López H.Bioresour Technol. 2008 Jul;99(10):4192-8. doi: 10.1016/j.biortech.2007.08.081. Epub 2007 Oct 24.PMID: 17951055
The biological treatment in the SBR led to removal efficiencies of 85% COD, 98% thiocyanate and 99% phenols for HRT of 115 h. Final concentrations in the effluent of 1.8 mg phenols/L, 5.4 mg SCN/L, 206 mg COD/L and 78 mg N-NH(4)(+)/L were obtained….543Cite
Kochany J, Lipczynska-Kochany E.Environ Technol. 2007 Sep;28(9):1007-13. doi: 10.1080/09593332808618859.PMID: 17910253544Cite
Role of NF-kappaB and MAPKs in light-induced photoreceptor apoptosis.
Yang LP, Zhu XA, Tso MO.Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4766-76. doi: 10.1167/iovs.06-0871.PMID: 17898303545Cite
Sidibé el H.Sante. 2007 Jan-Mar;17(1):41-50.PMID: 17897901 Free article. Review. French.
It is nonetheless underestimated, because the screening methods revolutionized 20 years ago are still not applied systematically. Additional factors include the thiocyanates in cassava, the selenium deficiency resulting in selenium-dependent glutathione peroxidase deficien …546Cite
Thejass P, Kuttan G.Immunopharmacol Immunotoxicol. 2007;29(2):173-86. doi: 10.1080/08923970701511728.PMID: 17849266547Cite
Croucher PD, Klingele MH, Noble A, Brooker S.Dalton Trans. 2007 Sep 28;(36):4000-7. doi: 10.1039/b707905b. Epub 2007 Aug 2.PMID: 17828360548Cite
Sundari SB, Venu L, Sunita Y, Raghunath M.Indian J Exp Biol. 2007 Jul;45(7):603-9.PMID: 17821855
Indices of reproductive performance such as percentage of conception, mortality of dams during pregnancy and parturition, litter size, and survival of pups till weaning were affected markedly by ID but not thiocyanate feeding. Neither ID nor thiocyanate feeding from …549Cite
Steinmaus C, Miller MD, Howd R.Environ Health Perspect. 2007 Sep;115(9):1333-8. doi: 10.1289/ehp.10300.PMID: 17805424 Free PMC article.
Decreases in thyroid hormone seen with perchlorate exposure could be even greater in people with concomitant exposure to agents such as thiocyanate that may affect the thyroid by mechanisms similar to those of perchlorate. …Agents other than tobacco smoke m …550Cite
Vanderver GB, Engel A, Lamm S.Thyroid. 2007 Aug;17(8):741-6. doi: 10.1089/thy.2006.0332.PMID: 17725431
BACKGROUND: Exposure to environmental thiocyanate through smoking has been suggested to lead to hypothyroxinemia, which potentially impairs brain development in the fetuses of affected women, though studies are conflicting. It was hypothesized that iodine status might modu …551Cite
Keap1 eye on the target: chemoprevention of liver cancer.
Yates MS, Kensler TW.Acta Pharmacol Sin. 2007 Sep;28(9):1331-42. doi: 10.1111/j.1745-7254.2007.00688.x.PMID: 17723167 Review.
Rodent studies have identified several classes of chemopreventive agents which induce cytoprotective genes. These inducers include phenolic antioxidants, dithiolethiones, isothiocyanates, and triterpenoids. …Much work remains to be done in order to take promising chemopr …552Cite
Tan S, Erol M, Attygalle A, Du H, Sukhishvili S.Langmuir. 2007 Sep 11;23(19):9836-43. doi: 10.1021/la701236v. Epub 2007 Aug 17.PMID: 17705409
Importantly, these positively charged Ag nanoparticles demonstrate superior SERS activity over negatively charged citrate reduced Ag nanoparticles for the detection of thiocyanate and perchlorate ions; therefore, they are promising candidates for sensing and detection of a …553Cite
Al-Ghannam SM.Spectrochim Acta A Mol Biomol Spectrosc. 2008 Apr;69(4):1188-94. doi: 10.1016/j.saa.2007.06.023. Epub 2007 Jun 28.PMID: 17689288554Cite
Kwak MK, Cho JM, Huang B, Shin S, Kensler TW.Free Radic Biol Med. 2007 Sep 1;43(5):809-17. doi: 10.1016/j.freeradbiomed.2007.05.029. Epub 2007 May 31.PMID: 17664144555Cite
Nair S, Hebbar V, Shen G, Gopalakrishnan A, Khor TO, Yu S, Xu C, Kong AN.Pharm Res. 2008 Feb;25(2):387-99. doi: 10.1007/s11095-007-9364-7. Epub 2007 Jul 27.PMID: 17657594556Cite
Minocycline and sulforaphane inhibited lipopolysaccharide-mediated retinal microglial activation.
Yang LP, Zhu XA, Tso MO.Mol Vis. 2007 Jul 9;13:1083-93.PMID: 17653053 Free PMC article.557Cite
Optimization of DNA isolation from legume nodules.
Krasova-Wade T, Neyra M.Lett Appl Microbiol. 2007 Jul;45(1):95-9. doi: 10.1111/j.1472-765X.2007.02149.x.PMID: 17594467
The best results were obtained with 0.5 mmol l(-1) guanidine thiocyanate, which resulted in greater DNA yield than with higher and lower concentrations or with DNAzol. CONCLUSION: The procedure using 0.5 mmol l(-1) guanidine thiocyanate yields the highest DNA amount …558Cite
A general purpose method for extracting RNA from Dictyostelium cells.
Pilcher KE, Gaudet P, Fey P, Kowal AS, Chisholm RL.Nat Protoc. 2007;2(6):1329-32. doi: 10.1038/nprot.2007.191.PMID: 17545970
This procedure is similar to other guanidine thiocyanate-based methods; however, it has been adjusted because of the large quantities of carbohydrate and nucleases found in Dictyostelium cells. …559Cite
Virus inactivation by protein denaturants used in affinity chromatography.
Roberts PL, Lloyd D.Biologicals. 2007 Oct;35(4):343-7. doi: 10.1016/j.biologicals.2007.02.005. Epub 2007 May 24.PMID: 17517521
The enveloped viruses Sindbis, herpes simplex-1 and vaccinia, and the non-enveloped virus polio-1 were effectively inactivated by 0.5 M sodium hydroxide, 6 M guanidinium thiocyanate, 8 M urea and 70% ethanol. However, pH 2.6, 3 M sodium thiocyanate, 6 M guanidinium …560Cite
Takahama U, Tanaka M, Oniki T, Hirota S.Free Radic Res. 2007 Jun;41(6):627-37. doi: 10.1080/10715760701218566.PMID: 17516234561Cite
Carbonic anhydrases as drug targets–an overview.
Supuran CT.Curr Top Med Chem. 2007;7(9):825-33. doi: 10.2174/156802607780636690.PMID: 17504127 Review.
CAs are inhibited primarily by two classes of compounds: the metal complexing anions (such as cyanide, cyanate, thiocyanate, azide, hydrogensulfide, etc) and the sulfonamides/sulfamates/sulfamides possessing the general formula RXSO(2)NH(2) (R = aryl; hetaryl; perhaloalkyl …562Cite
A novel host defense system of airways is defective in cystic fibrosis: update.
Banfi B.Am J Respir Crit Care Med. 2007 May 1;175(9):967. doi: 10.1164/ajrccm.175.9.967.PMID: 17446344 No abstract available.563Cite
Singh G, Maurya S, DeLampasona MP, Catalan CA.Food Chem Toxicol. 2007 Sep;45(9):1650-61. doi: 10.1016/j.fct.2007.02.031. Epub 2007 Feb 28.PMID: 17408833
Moreover, it was further supported by other complementary antioxidant assays such as ferric thiocyanate method in linoleic acid system, reducing power, chelating and scavenging effects on 1,1′-diphenyl-2-picrylhydrazyl (DPPH) and hydroxyl radicals. In antimicrobial …564Cite
Chomczynski P, Sacchi N.Nat Protoc. 2006;1(2):581-5. doi: 10.1038/nprot.2006.83.PMID: 17406285
The principle at the basis of the method is that RNA is separated from DNA after extraction with an acidic solution containing guanidinium thiocyanate, sodium acetate, phenol and chloroform, followed by centrifugation. Under acidic conditions, total RNA remains in the uppe …565Cite
Pedemonte N, Caci E, Sondo E, Caputo A, Rhoden K, Pfeffer U, Di Candia M, Bandettini R, Ravazzolo R, Zegarra-Moran O, Galietta LJ.J Immunol. 2007 Apr 15;178(8):5144-53. doi: 10.4049/jimmunol.178.8.5144.PMID: 17404297 Free article.
SCN(-) (thiocyanate) is an important physiological anion involved in innate defense of mucosal surfaces. SCN(-) is oxidized by H(2)O(2), a reaction catalyzed by lactoperoxidase, to produce OSCN(-) (hypothiocyanite), a molecule with antimicrobial activity. Given the …566Cite
Iodine deficiency disorders in India.
Laway BA, Zargar AH.J Indian Med Assoc. 2006 Oct;104(10):554-6.PMID: 17380818 Review.
Goitre endemicity of varying degree persists among school children even a decade after successful salt iodisation in India. Some other factors like high thiocyanate exposure or auto-immune thyroid disease could be responsible for such a phenomenon….567Cite
Effect of prion decontamination protocols on nickel-titanium rotary surfaces.
Sonntag D, Peters OA.J Endod. 2007 Apr;33(4):442-6. doi: 10.1016/j.joen.2006.12.012. Epub 2007 Feb 23.PMID: 17368335568Cite
Chemical, thermal and pH-induced equilibrium unfolding studies of Fusarium solani lectin.
Khan F, Ahmad A, Khan MI.IUBMB Life. 2007 Jan;59(1):34-43. doi: 10.1080/15216540601178075.PMID: 17365178 Free article.
The effect of urea, guanidine thiocyanate, temperature and pH was studied on the conformational stability of Fusarium solani lectin. …Thermal denaturation was also carried out in the presence of a low concentration of guanidine thiocyanate. Change in the enthalpy …569Cite
Rungapamestry V, Duncan AJ, Fuller Z, Ratcliffe B.Br J Nutr. 2007 Apr;97(4):644-52. doi: 10.1017/S0007114507381403.PMID: 17349076 Clinical Trial.570Cite
Wiangnon K, Raksajit W, Incharoensakdi A.FEMS Microbiol Lett. 2007 May;270(1):139-45. doi: 10.1111/j.1574-6968.2007.00667.x. Epub 2007 Feb 16.PMID: 17302934
The ATPase was insensitive to N-ethylmaleimide, nitrate, thiocyanate, azide and ouabain, but was substantially inhibited by orthovanadate and DCCD. …571Cite
Spherulitic growth of hen egg-white lysozyme crystals.
Heijna MC, Theelen MJ, van Enckevort WJ, Vlieg E.J Phys Chem B. 2007 Feb 22;111(7):1567-73. doi: 10.1021/jp0643294. Epub 2007 Jan 31.PMID: 17263569
Here, we present an in situ study on lysozyme spherulites grown from sodium nitrate and sodium thiocyanate solutions, investigating their morphology and growth kinetics using optical microscopy. …572Cite
Gülçin I, Elmastaş M, Aboul-Enein HY.Phytother Res. 2007 Apr;21(4):354-61. doi: 10.1002/ptr.2069.PMID: 17221941
In the present study, the possible radical scavenging and antioxidant activity of the water (WEB) and ethanol extracts (EEB) of basil was investigated using different antioxidant methodologies: 1,1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging, scavenging of superoxid …573Cite
Castritsi-Catharios J, Bourdaniotis N, Persoone G.Chemosphere. 2007 Apr;67(6):1127-32. doi: 10.1016/j.chemosphere.2006.11.033. Epub 2007 Jan 10.PMID: 17217989574Cite
Farooqui MY, Trevino M, Garcia I.Res Commun Mol Pathol Pharmacol. 2007-2008;120-121(1-6):79-92.PMID: 21469506
The rats were observed for mortality, cholinomimetic and central nervous system (CNS) effects and urinary dysfunction for 6 hr. The concentrations of cyanide, thiocyanate and glutathione (GSH) were determined in blood, liver, kidney and brain. Alcohol and alcohol + caffein …575Cite
[Retention of nucleic acid integrity in guanidine thiocyanate lysates of whole blood].
Kravchenko AV, Chetverina EV, Chetverin AB.Bioorg Khim. 2006 Nov-Dec;32(6):609-14. doi: 10.1134/s1068162006060070.PMID: 17180911 Russian.
High-molecular-mass RNA and DNA have been shown to retain their integrity for three days at room temperature, no less than two weeks at +4 degrees C, and more than a year at -20 degrees C when whole blood samples are stored as lysates containing 4 M guanidine thiocyanate. …576Cite
Dolai S, Yadav RK, Datta AK, Adak S.Biochim Biophys Acta. 2007 Feb;1770(2):247-56. doi: 10.1016/j.bbagen.2006.10.001. Epub 2006 Oct 5.PMID: 17118560577Cite
Hudson VM.Med Hypotheses. 2007;68(4):919-20. doi: 10.1016/j.mehy.2006.09.033. Epub 2006 Nov 13.PMID: 17097824 No abstract available.578Cite
A novel host defense system of airways is defective in cystic fibrosis.
Moskwa P, Lorentzen D, Excoffon KJ, Zabner J, McCray PB Jr, Nauseef WM, Dupuy C, Bánfi B.Am J Respir Crit Care Med. 2007 Jan 15;175(2):174-83. doi: 10.1164/rccm.200607-1029OC. Epub 2006 Nov 2.PMID: 17082494 Free PMC article.
This innate immune activity has been attributed to mucociliary clearance and antimicrobial polypeptides of airway surface liquid. Defective airway immunity characterizes cystic fibrosis (CF), a disease caused by mutations in the CF transmembrane conductance regulator, a ch …579Cite
Nagy P, Alguindigue SS, Ashby MT.Biochemistry. 2006 Oct 17;45(41):12610-6. doi: 10.1021/bi061015y.PMID: 17029415580Cite
Iodine nutritional status of children in North East India.
Chandra AK, Singh LH, Tripathy S, Debnath A, Khanam J.Indian J Pediatr. 2006 Sep;73(9):795-8. doi: 10.1007/BF02790388.PMID: 17006037
One hundred twenty urine samples were analysed for iodine and thiocyanate respectively. One hundred and five edible salt samples were also collected from the households to evaluate the iodine content. …The median urinary iodine levels in the studied areas were in the ran …581Cite
Thejass P, Kuttan G.Immunopharmacol Immunotoxicol. 2006;28(3):443-57. doi: 10.1080/08923970600928049.PMID: 16997793582Cite
Thippeswamy R, Gouda KG, Rao DH, Martin A, Gowda LR.J Agric Food Chem. 2006 Sep 20;54(19):7014-9. doi: 10.1021/jf061715+.PMID: 16968057583Cite
van Doorn HR, Bruijnesteijn van Coppenraet ES, Duim B, Vandenbroucke-Grauls CM, Weel JF, Dankert J, Kuijper EJ, de Jong MD.Eur J Clin Microbiol Infect Dis. 2006 Oct;25(10):673-5. doi: 10.1007/s10096-006-0194-z.PMID: 16964511 No abstract available.584Cite
Al Janobi AA, Mithen RF, Gasper AV, Shaw PN, Middleton RJ, Ortori CA, Barrett DA.J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Dec 5;844(2):223-34. doi: 10.1016/j.jchromb.2006.07.007. Epub 2006 Aug 23.PMID: 16931178585Cite
Chandra AK, Mukhopadhyay S, Ghosh D, Tripathy S.Indian J Exp Biol. 2006 Aug;44(8):653-61.PMID: 16924836
The consumption pattern of iodine and goitrogens of cyanogenic origin was evaluated by measuring urinary iodine and thiocyanate levels respectively. After chronic radish feeding, increased weight of thyroid gland, decreased thyroid peroxidase activity, reduced thyroid horm …586Cite
Antibody response after single-visit full-mouth ultrasonic debridement versus quadrant-wise therapy.
Wang D, Koshy G, Nagasawa T, Kawashima Y, Kiji M, Nitta H, Oda S, Ishikawa I.J Clin Periodontol. 2006 Sep;33(9):632-8. doi: 10.1111/j.1600-051X.2006.00963.x. Epub 2006 Jul 20.PMID: 16856899 Clinical Trial.
Serum antibody titres and avidity to Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans, Prevotella intermedia and Treponema denticola were determined by enzyme-linked immunosorbent assay (ELISA) and thiocyanate ELISA, respectively. RESULTS: IgG titres to P. gi …587Cite
Reactivity of DNA guanyl radicals with phenolate anions.
Ly A, Bandong SL, Tran NQ, Sullivan KJ, Milligan JR.J Phys Chem B. 2005 Jul 14;109(27):13368-74. doi: 10.1021/jp050495k.PMID: 16852669
Electron-deficient guanine species are major intermediates produced in DNA by the direct effect of ionizing radiation (ionization of the DNA itself) because of preferential hole migration within DNA to guanine bases. By using thiocyanate ions to modify the indirect effect …588Cite
Cationic peptides containing tyrosine protect against radiation-induced oxidative DNA damage.
Ly A, Bullick S, Won JH, Milligan JR.Int J Radiat Biol. 2006 Jun;82(6):421-33. doi: 10.1080/09553000600771531.PMID: 16846977
MATERIALS AND METHODS: We made use of tetralysine ligands to ensure binding to DNA and to condense the DNA, and simulated direct-type damage by using gamma irradiation in the presence of thiocyanate ions. These ligands contained an additional C terminal amino acid. Phenyla …589Cite
Vázquez I, Rodríguez J, Marañón E, Castrillón L, Fernández Y.J Hazard Mater. 2006 Oct 11;137(3):1681-8. doi: 10.1016/j.jhazmat.2006.05.007. Epub 2006 May 9.PMID: 16846684
The main pollutants to be removed are organic matter, especially phenols, thiocyanate and ammonium nitrogen. The concentrations of the main pollutants in the wastewater during the study ranged between 922 and 1,980 mg COD/L, 133 and 293 mg phenol/L, 176 and 362 mg SCN/L an …590Cite
Chandra AK, Tripathy S, Ghosh D, Debnath A, Mukhopadhyay S.Asia Pac J Clin Nutr. 2006;15(3):357-61.PMID: 16837428 Free article.
A total of 2050 children were clinically examined for goiter and 240 urine samples were analyzed for iodine and thiocyanate respectively; iodine content in 48 water samples and 210 salt samples were also measured. Results indicate that the studied region is clinically seve …591Cite
Van Opstal I, Bagamboula CF, Theys T, Vanmuysen SC, Michiels CW.J Appl Microbiol. 2006 Jul;101(1):242-50. doi: 10.1111/j.1365-2672.2006.03002.x.PMID: 16834612
AIMS: To study the bactericidal properties of the lactoperoxidase (LPER)-thiocyanate and soybean peroxidase (SBP)-thiocyanate systems at low pH, their efficiency for inactivation of Escherichia coli and Shigella in acidic fruit and vegetable juices, their effect on …592Cite
Khan A, Sarkar D.Microb Pathog. 2006 Aug-Sep;41(2-3):90-5. doi: 10.1016/j.micpath.2006.04.006. Epub 2006 Jun 27.PMID: 16806798
At these concentrations, neither of azide, thiocyanate nor chlorate had any significant effect on cell growth under aerobic condition. In Wayne’s culture model, thiocyanate and chlorate inhibited the growth of M. smegmatis by almost 2 logs at the same concentrations …593Cite
De Groef B, Decallonne BR, Van der Geyten S, Darras VM, Bouillon R.Eur J Endocrinol. 2006 Jul;155(1):17-25. doi: 10.1530/eje.1.02190.PMID: 16793945 Free article. Review.
RESULTS: The relative potencies of prevalent environmental NIS inhibitors (nitrate, thiocyanate and perchlorate) to inhibit iodine uptake have been estimated repeatedly with robust results. Our calculations show that nitrate and thiocyanate, acquired through drinkin …594Cite
Vázquez I, Rodríguez J, Marañón E, Castrillón L, Fernández Y.J Hazard Mater. 2006 Oct 11;137(3):1773-80. doi: 10.1016/j.jhazmat.2006.05.018.PMID: 16766120
The concentrations of ammonium nitrogen (NH(4)(+) -N), phenols, chemical oxygen demand (COD) and thiocyanate (SCN(-)) in the wastewater ranged between 504 and 2,340, 110 and 350, 807 and 3,275 and 185 and 370 mg/L, respectively. …Batch experiments were performed to study …595Cite
Nutritional epidemiology and thyroid hormone metabolism.
Vanderpas J.Annu Rev Nutr. 2006;26:293-322. doi: 10.1146/annurev.nutr.26.010506.103810.PMID: 16704348 Review.
Inductively coupled plasma-mass spectrometry brings at least a definitive gold standard for iodine measurement and thyroid hormone measurement. Thiocyanate overload has been clearly documented as a goitrogen in Central Africa, and when associated with selenium deficiency, …596Cite
Subclinical hypothyroidism in HIV-infected patients is not an autoimmune disease.
Beltran S, Lescure FX, El Esper I, Schmit JL, Desailloud R.Horm Res. 2006;66(1):21-6. doi: 10.1159/000093228. Epub 2006 May 9.PMID: 16685132
Reverse T3, binding protein levels, the TSH response to thyrotropin-releasing hormone, urinary iodine, plasma selenium and thiocyanate levels did not differ. IFNgamma levels were lower in the subclinical hypothyroidism group (pg/ml) (9.1 [0.0, 22.7] vs. 19.5 [0.0, 40.9], p …597Cite
Gülçin I, Mshvildadze V, Gepdiremen A, Elias R.Phytomedicine. 2006 May;13(5):343-51. doi: 10.1016/j.phymed.2005.03.009. Epub 2005 Sep 16.PMID: 16635742
In the current study we investigated the possible antiradical and antioxidant activity of the monodesmosides (MLS) and crude extract (CELS) of Leontice smirnowii using different antioxidant tests: 1,1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging, scavenging of supero …598Cite
Optimization of the components concentrations of the lactoperoxidase system by RSM.
Adolphe Y, Jacquot M, Linder M, Revol-Junelles AM, Millière JB.J Appl Microbiol. 2006 May;100(5):1034-42. doi: 10.1111/j.1365-2672.2006.02892.x.PMID: 16630004
At 4 degrees C, no interaction between factors occurred. At 25 degrees C, thiocyanate peroxidation was affected by GOD/glucose, GOD/pH and LPO/pH. Thiocyanate peroxidation was mainly increased by glucose and LPO factors. …The antimicrobial efficiency of LP- …599Cite
[Mechanical periodontal treatment combined with tetracycline for aggressive periodontitis].
Zhang XQ, Xie M, Zhang HF, Huang SG, Zhang Y.Nan Fang Yi Ke Da Xue Xue Bao. 2006 Apr;26(4):509-11, 514.PMID: 16624768 Clinical Trial. Chinese.
The avidity of serum IgG against Pg LPS was measured by ELISA with thiocyanate elution before and after periodontal treatment. RESULTS: Compared with patients with exclusive mechanical periodontal treatment, patients with combined treatments showed significant improvement …600Cite
Thiocyanate is an efficient endogenous scavenger of the phagocytic killing agent hypobromous acid.
Nagy P, Beal JL, Ashby MT.Chem Res Toxicol. 2006 Apr;19(4):587-93. doi: 10.1021/tx050338c.PMID: 16608171
Furthermore, the product of the nonenzymatic reaction of HOBr and SCN-, hypothiocyanite (OSCN-), is an effective antimicrobial that is relatively innocuous toward mammalian cell lines. Since one of the principal charges of eosinophil cells is to clear extracellular parasit …
Dua S, Maclean MJ, Fitzgerald M, McAnoy AM, Bowie JH.J Phys Chem A. 2006 Apr 13;110(14):4930-6. doi: 10.1021/jp058144t.PMID: 16599464
The hypothiocyanate anion (OSCN)(-) is reported to be a major product of the lactoperoxidase/H(2)O(2)/(SCN)(-) system, and this anion is proposed to have significant antimicrobial properties. The collision induced (CID) negative ion mass spectrum of “(OSCN)(-)” has been re …602Cite
Modulation of polyene antibiotics self-association by ions from the Hofmeister series.
Toledo Grijalba M, Chéron M, Borowski E, Bolard J, Schreier S.Biochim Biophys Acta. 2006 Jun;1760(6):973-9. doi: 10.1016/j.bbagen.2006.02.004. Epub 2006 Mar 3.PMID: 16563634
Ions from the Hofmeister series alter water properties: while kosmotropes (water structure makers-sulfate, citrate, phosphate) decrease solute solubility, chaotropes (water structure breakers-perchlorate, thiocyanate, trichloroacetate, and the neutral molecule urea) have o …603Cite
Wacharapluesadee S, Ruangvejvorachai P, Hemachudha T.J Virol Methods. 2006 Jun;134(1-2):267-71. doi: 10.1016/j.jviromet.2006.02.002. Epub 2006 Mar 9.PMID: 16529825604Cite
Tang L, Li G, Song L, Zhang Y.Anticancer Drugs. 2006 Mar;17(3):297-305. doi: 10.1097/00001813-200603000-00008.PMID: 16520658605Cite
Hofer T, Seo AY, Prudencio M, Leeuwenburgh C.Biol Chem. 2006 Jan;387(1):103-11. doi: 10.1515/BC.2006.014.PMID: 16497170
We developed a novel method for the simultaneous extraction and analysis of total tissue RNA and DNA to quantify the RNA and DNA oxidation products 8-oxo-7,8-dihydroguanosine and 8-oxo-7,8-dihydro-2′-deoxyguanosine using HPLC coupled to electrochemical detection (HPLC-ECD). The p …606Cite
Mio K, Kirkham J, Bonass WA.Anal Biochem. 2006 Apr 15;351(2):314-6. doi: 10.1016/j.ab.2005.12.031. Epub 2006 Jan 20.PMID: 16460656 No abstract available.607Cite
Chandra AK, Tripathy S, Ghosh D, Debnath A, Mukhopadhyay S.Indian J Med Res. 2005 Nov;122(5):419-24.PMID: 16456256
The present investigation was thus undertaken to study the total goitre rate, urinary iodine and thiocyanate excretion pattern of the school going children, iodine content in edible salt and drinking water in the Sundarban delta of South 24-Parganas in West Bengal. METHODS …608Cite
The role of thiocyanate in the etiology of goiter in an industrial metropolitan area.
Brauer VF, Below H, Kramer A, Führer D, Paschke R.Eur J Endocrinol. 2006 Feb;154(2):229-35. doi: 10.1530/eje.1.02076.PMID: 16452535
OBJECTIVE: Thiocyanate (SCN-) has concentration dependent antithyroid properties and a role in the etiology of goiter has been suggested in several studies. …609Cite
Myeloperoxidase metabolizes thiocyanate in a reaction driven by nitric oxide.
Galijasevic S, Saed GM, Hazen SL, Abu-Soud HM.Biochemistry. 2006 Jan 31;45(4):1255-62. doi: 10.1021/bi051438k.PMID: 16430221
We examined the potential physiological relevance of myeloperoxidase (MPO)-nitric oxide (NO) interactions as they may relate to the cosubstrate, pseudo halide thiocyanate (SCN(-)), and substrate switching. Direct spectroscopic and rapid kinetics studies revealed that SCN(- …610Cite
Eweis M, Elkholy SS, Elsabee MZ.Int J Biol Macromol. 2006 Feb 28;38(1):1-8. doi: 10.1016/j.ijbiomac.2005.12.009. Epub 2006 Jan 18.PMID: 16413607
Chitosan (CS) was modified by reaction with benzoyl thiocyanate to give a thiourea derivative (TUCS). The antifungal behavior of chitosan and its thiourea derivative was investigated in vitro on the mycelial growth, sporulation and germination of conidia or sclerotia of th …611Cite
Interaction of hypohalous acids and heme peroxidases with unsaturated phosphatidylcholines.
Spalteholz H, Wenske K, Arnhold J.Biofactors. 2005;24(1-4):67-76. doi: 10.1002/biof.5520240108.PMID: 16403965612Cite
Ravaschino EL, Docampo R, Rodriguez JB.J Med Chem. 2006 Jan 12;49(1):426-35. doi: 10.1021/jm050922i.PMID: 16392828
As a part of our project aimed at the search for new safe chemotherapeutic and chemoprophylactic agents against American trypanosomiasis (Chagas’s disease), a series of phosphinopeptides structurally related to glutathione was designed, synthesized, and evaluated as antipr …613Cite
Killeen ME, Englert JA, Stolz DB, Song M, Han Y, Delude RL, Kellum JA, Fink MP.J Pharmacol Exp Ther. 2006 Mar;316(3):1070-9. doi: 10.1124/jpet.105.092841. Epub 2005 Dec 28.PMID: 16382025614Cite
Dietary isothiocyanates modify mitochondrial functions through their electrophilic reaction.
Kawakami M, Harada N, Hiratsuka M, Kawai K, Nakamura Y.Biosci Biotechnol Biochem. 2005 Dec;69(12):2439-44. doi: 10.1271/bbb.69.2439.PMID: 16377906 Free article.615Cite
Mason PE, Dempsey CE, Neilson GW, Brady JW.J Phys Chem B. 2005 Dec 22;109(50):24185-96. doi: 10.1021/jp052799c.PMID: 16375411
Neutron diffraction experiments and molecular dynamics simulations are used to study the structure of aqueous solutions of two electrolytes: guanidinium sulfate (a mild protein conformation stabilizer) and guanidinium thiocyanate (a powerful denaturant). The MD simulations …616Cite
van Dalen CJ, Winterbourn CC, Kettle AJ.Biochem J. 2006 Mar 15;394(Pt 3):707-13. doi: 10.1042/BJ20051470.PMID: 16336215 Free PMC article.
It uses hydrogen peroxide to oxidize thiocyanate and bromide to their respective hypohalous acids. Nitrite is also a substrate for eosinophil peroxidase. …Spectral studies showed that nitrite reduced the enzyme to its compound II form, which is a redox intermediate conta …617Cite
Wojciechowski G, Huang L, Ortiz de Montellano PR.J Am Chem Soc. 2005 Nov 16;127(45):15871-9. doi: 10.1021/ja054084t.PMID: 16277530
The mammalian peroxidases eosinophil peroxidase, lactoperoxidase (LPO), and myeloperoxidase oxidize thiocyanate to the antimicrobial agents hypothiocyanous acid (HOSCN) and (SCN)2 and are part of a defense system that protects the host from infections. …Mas …618Cite
Sermon J, Wevers EM, Jansen L, De Spiegeleer P, Vanoirbeek K, Aertsen A, Michiels CW.Appl Environ Microbiol. 2005 Nov;71(11):6515-23. doi: 10.1128/AEM.71.11.6515-6523.2005.PMID: 16269676 Free PMC article.
The enzyme lactoperoxidase is part of the innate immune system in vertebrates and owes its antimicrobial activity to the formation of oxidative reaction products from various substrates. In a previous study, we have reported that, with thiocyanate as a substrate, th …619Cite
Antioxidant and antiradical activities of L-carnitine.
Gülçin I.Life Sci. 2006 Jan 18;78(8):803-11. doi: 10.1016/j.lfs.2005.05.103. Epub 2005 Oct 25.PMID: 16253281
Total antioxidant activity was measured according to ferric thiocyanate method. alpha-tocopherol and trolox, a water-soluble analogue of tocopherol, were used as the reference antioxidant compounds. …620Cite
Risk factors for goiter in a previously iodine-deficient region.
Völzke H, Schwahn C, Kohlmann T, Kramer A, Robinson DM, John U, Meng W.Exp Clin Endocrinol Diabetes. 2005 Oct;113(9):507-15. doi: 10.1055/s-2005-865741.PMID: 16235152
Sociodemographic characteristics, smoking and alcohol drinking habits, marital status, education level, urine thiocyanate concentrations, and specifically in women, parity and previous or current use of oral contraceptives and hormone replacement therapy, were considered a …621Cite
Hwang JW, Park JS, Jo EH, Kim SJ, Yoon BS, Kim SH, Lee YS, Kang KS.J Agric Food Chem. 2005 Oct 19;53(21):8205-10. doi: 10.1021/jf051747h.PMID: 16218665622Cite
Uğuz MT, Ozdemir H.Prikl Biokhim Mikrobiol. 2005 Jul-Aug;41(4):397-401.PMID: 16212035
Bovine LPO showed high antibacterial activity in 100 mM thiocyanate–100 mM H2O2 medium for some pathogenic bacteria, such as Aeromonas hydrophila ATCC 7966, Micrococcus luteus LA 2971, Mycobacterium smegmatis RUT, Bacillus subtilis IMG 22, Pseudomonas pyocyanea, Bacillus …623Cite
[Fluorescence microscopic study of the microorganisms treated with chaotropic agents].
Duda VI, Danilevich VN, Akimov VN, Suzina NE, Dmitriev VV, Shorokhova AP.Mikrobiologiia. 2005 Jul-Aug;74(4):505-10.PMID: 16211854 Russian.
The yeasts Saccharomyces cerevisiae and Pichia pastoris and the bacteria Micrococcus luteus, Bacillus subtilis, and Anaerobacter polyendosporus have been treated with the chaotropic agents guanidine hydrochloride and guanidine thiocyanate and certain detergents and …624Cite
Fang MZ, Chen D, Sun Y, Jin Z, Christman JK, Yang CS.Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):7033-41. doi: 10.1158/1078-0432.CCR-05-0406.PMID: 16203797625Cite
Shen G, Xu C, Chen C, Hebbar V, Kong AN.Cancer Chemother Pharmacol. 2006 Feb;57(3):317-27. doi: 10.1007/s00280-005-0050-3. Epub 2005 Sep 17.PMID: 16170570626Cite
Conaway CC, Wang CX, Pittman B, Yang YM, Schwartz JE, Tian D, McIntee EJ, Hecht SS, Chung FL.Cancer Res. 2005 Sep 15;65(18):8548-57. doi: 10.1158/0008-5472.CAN-05-0237.PMID: 16166336
The results of the study provide a basis for future evaluation of the potential of phenethyl isothiocyanate and sulforaphane and their conjugates as chemopreventive agents in smokers and ex-smokers with early lung lesions….627Cite
Tulsawani RK, Debnath M, Pant SC, Kumar O, Prakash AO, Vijayaraghavan R, Bhattacharya R.Chem Biol Interact. 2005 Sep 10;156(1):1-12. doi: 10.1016/j.cbi.2005.05.001.PMID: 16154552
Reduced levels of GSH and enhanced levels of MDA in brain were observed. Increased levels of blood thiocyanate were observed in all the treatments of KCN. Additionally, KCN also produced various histological changes in the brain, heart, liver and kidney. …628Cite
Arutchelvan V, Kanakasabai V, Nagarajan S, Muralikrishnan V.J Hazard Mater. 2005 Dec 9;127(1-3):238-43. doi: 10.1016/j.jhazmat.2005.04.043. Epub 2005 Sep 8.PMID: 16154261
The organisms degrade phenol even in the presence of toxicants like thiocyanate, sulphide and cyanide. The organisms can be effectively used for treating high strength phenol containing thiocyanate, sulphide and cyanide. …629Cite
Nakagawa T, Sawada N, Yamaguchi M.Int J Mol Med. 2005 Oct;16(4):637-43.PMID: 16142398630Cite
New drug salt formation in biodegradable microspheres.
Al-Maaieh A, Flanagan DR.Int J Pharm. 2005 Oct 13;303(1-2):153-9. doi: 10.1016/j.ijpharm.2005.06.029.PMID: 16125886631Cite
Senthilmohan R, Kettle AJ.Arch Biochem Biophys. 2006 Jan 15;445(2):235-44. doi: 10.1016/j.abb.2005.07.005. Epub 2005 Aug 3.PMID: 16125131
Myeloperoxidase and eosinophil peroxidase use hydrogen peroxide to oxidize halides and thiocyanate to their respective hypohalous acids. Myeloperoxidase produces mainly hypochlorous acid and hypothiocyanite. …632Cite
Hwang ES, Jeffery EH.J Med Food. 2005 Summer;8(2):198-203. doi: 10.1089/jmf.2005.8.198.PMID: 16117612633Cite
Origin, structure, and biological activities of peroxidases in human saliva.
Ihalin R, Loimaranta V, Tenovuo J.Arch Biochem Biophys. 2006 Jan 15;445(2):261-8. doi: 10.1016/j.abb.2005.07.004. Epub 2005 Aug 2.PMID: 16111647 Review.
In human saliva the major function of hSPO and hMPO is to catalyze the oxidation of thiocyanate (SCN(-)) in the presence of hydrogen peroxide (H(2)O(2)) resulting in end products of wide antimicrobial potential. …Similar peroxidation reactions inactivate some muta …634Cite
Safe method for isolation of prion protein and diagnosis of Creutzfeldt-Jakob disease.
Bastian FO, McDermott ME, Perry AS, Carver LA, Dash S, Garry RF.J Virol Methods. 2005 Dec;130(1-2):133-9. doi: 10.1016/j.jviromet.2005.06.024. Epub 2005 Aug 15.PMID: 16102852
Since CJD brain samples are infectious at all stages of the prion extraction process, we set out to develop a laboratory safe method for prion purification. We lysed the tissues with guanidine thiocyanate followed by phenol extraction of the proteins. Western blotting usin …635Cite
Kurtaran R, Yildirim LT, Azaz AD, Namli H, Atakol O.J Inorg Biochem. 2005 Oct;99(10):1937-44. doi: 10.1016/j.jinorgbio.2005.05.016.PMID: 16054699 Free article.
The minimum inhibitory concentration values were calculated. It has been found that antimicrobial activities of the complexes are higher than the free ligand….636Cite
Effect of the lactoperoxidase system against three major causal agents of disease in mangoes.
Le Nguyen DD, Ducamp MN, Dornier M, Montet D, Loiseau G.J Food Prot. 2005 Jul;68(7):1497-500. doi: 10.4315/0362-028x-68.7.1497.PMID: 16013395 Free article.
This compound is essentially used to convert thiocyanate into hypothiocyanate during the lactoperoxidase reaction. The potential of the LPS for the postharvest treatment of the fruits for controlling microbial diseases was thus demonstrated. …637Cite
Effect of glycosylation on the catalytic and conformational stability of homologous alpha-amylases.
Srimathi S, Jayaraman G.Protein J. 2005 Feb;24(2):79-88. doi: 10.1007/s10930-004-1514-8.PMID: 16003949638Cite
De Spiegeleer P, Sermon J, Vanoirbeek K, Aertsen A, Michiels CW.Appl Environ Microbiol. 2005 Jul;71(7):3512-8. doi: 10.1128/AEM.71.7.3512-3518.2005.PMID: 16000755 Free PMC article.
Lactoperoxidase is an enzyme that contributes to the antimicrobial defense in secretory fluids and that has attracted interest as a potential biopreservative for foods and other perishable products. Its antimicrobial activity is based on the formation of hypothiocya …639Cite
Haldar S, De Majumdar S, Chakravorty S, Tyagi JS, Bhalla M, Sen MK.J Clin Microbiol. 2005 Jul;43(7):3580-1. doi: 10.1128/JCM.43.7.3580-3581.2005.PMID: 16000514 Free PMC article. No abstract available.640Cite
Schönfeld P, Montero L, Fabian J.Biophys J. 2005 Sep;89(3):1504-15. doi: 10.1529/biophysj.105.059006. Epub 2005 Jun 24.PMID: 15980184 Free PMC article.
Inhibition of gastric acid secretion by thiocyanate is explained by a protonophoric mechanism assuming that thiocyanate induces a H(+) back flux from the acidic gastric lumen into the parietal cells of gastric mucosa. …To rationalize the protonophoric activity of …641Cite
Fimognari C, Berti F, Cantelli-Forti G, Hrelia P.Environ Mol Mutagen. 2005 Dec;46(4):260-7. doi: 10.1002/em.20156.PMID: 15957190
The fraction of apoptotic cells was increased after co- or post-treatment with sulforaphane and EMS and MMC, suggesting that sulforaphane-mediated apoptosis may remove highly damaged cells induced by these agents. Other mechanisms are involved in the anti-genotoxic activit …642Cite
Synthesis of 2-(aminocarbonylmethylthio)-1H-imidazoles as novel Capravirine analogues.
Loksha YM, el-Barbary AA, el-Badawi MA, Nielsen C, Pedersen EB.Bioorg Med Chem. 2005 Jul 1;13(13):4209-20. doi: 10.1016/j.bmc.2005.04.024.PMID: 15896963
Different analogues of Capravirine (AG-1549) or S-1153 were prepared by synthesis of 2-(5-benzyl-4-isopropyl-1-methyl-2,3-dihydro-1H-imidazol-2-ylthio)acetamide (3a-c), ethyl [5-benzyl-1-(ethoxymethyl)-4-ethyl-1H-imidazol-2-ylthio]acetate (10), 2-[5-alkyl-4-substituted 1-(pyridin …643Cite
Thiocyanate modulates the catalytic activity of mammalian peroxidases.
Tahboub YR, Galijasevic S, Diamond MP, Abu-Soud HM.J Biol Chem. 2005 Jul 15;280(28):26129-36. doi: 10.1074/jbc.M503027200. Epub 2005 May 13.PMID: 15894800 Free article.
We investigated the potential role of the co-substrate, thiocyanate (SCN-), in modulating the catalytic activity of myeloperoxidase (MPO) and other members of the mammalian peroxidase superfamily (lactoperoxidase (LPO) and eosinophil peroxidase (EPO)). …644Cite
Mashaly MM, El-Shafiy HF, El-Maraghy SB, Habib HA.Spectrochim Acta A Mol Biomol Spectrosc. 2005 Jun;61(8):1853-69. doi: 10.1016/j.saa.2004.06.056.PMID: 15863057645Cite
Apolipoprotein J (clusterin) activates rodent microglia in vivo and in vitro.
Xie Z, Harris-White ME, Wals PA, Frautschy SA, Finch CE, Morgan TE.J Neurochem. 2005 May;93(4):1038-46. doi: 10.1111/j.1471-4159.2005.03065.x.PMID: 15857407 Free article.
As a functional measure, apoJ-activated microglia secreted neurotoxic agents in a microglia-neuron co-culture model. We hypothesize that ApoJ contributes to chronic inflammation and neurotoxicity through direct effects on microglia….646Cite
Standard reduction potentials of all couples of the peroxidase cycle of lactoperoxidase.
Furtmüller PG, Arnhold J, Jantschko W, Zederbauer M, Jakopitsch C, Obinger C.J Inorg Biochem. 2005 May;99(5):1220-9. doi: 10.1016/j.jinorgbio.2005.02.021.PMID: 15833345
Lactoperoxidase (LPO) is found in mucosal surfaces and exocrine secretions including milk, tears and saliva and has physiological significance in antimicrobial defense. Its predominant physiological role is to convert hydrogen peroxide and thiocyanate in hypothiocya …647Cite
Singh SV, Srivastava SK, Choi S, Lew KL, Antosiewicz J, Xiao D, Zeng Y, Watkins SC, Johnson CS, Trump DL, Lee YJ, Xiao H, Herman-Antosiewicz A.J Biol Chem. 2005 May 20;280(20):19911-24. doi: 10.1074/jbc.M412443200. Epub 2005 Mar 11.PMID: 15764812 Free article.648Cite
Unique stress response to the lactoperoxidase-thiocyanate enzyme system in Escherichia coli.
Sermon J, Vanoirbeek K, De Spiegeleer P, Van Houdt R, Aertsen A, Michiels CW.Res Microbiol. 2005 Mar;156(2):225-32. doi: 10.1016/j.resmic.2004.09.012. Epub 2004 Dec 15.PMID: 15748988 Free article.
Using a differential fluorescence induction approach, we screened a promoter trap library constructed in a vector with a promoterless gfp gene for Escherichia coli MG1655 promoters that are induced upon challenge with the antimicrobial lactoperoxidase-thiocyanate en …649Cite
Avidity as a parameter for diphtheria vaccine efficacy.
el-Kady EM.Egypt J Immunol. 2004;11(1):47-54.PMID: 15724386
The avidity of antibodies (Abs) to diphtheria Toxin (DT), toxoids (DTo) and the DT binding site (DTBS) was investigated in sera from guinea bigs vaccinated with various DTo. Measurement of avidity by the thiocyanate procedure revealed that, the maturation patterns of Abs t …650Cite
Cho MS, Lee IS, Kang SH, Kim YH.Chemistry. 2005 Feb 18;11(5):1452-8. doi: 10.1002/chem.200400676.PMID: 15651025
A novel samarium diiodide (SmI2) promoted intramolecular cyclization of beta-ketoisothiocyanate, derived from alpha,beta-unsaturated esters and ammonium thiocyanate led to alpha-hydroxythiolactams and/or thiolactams in high yields. Treatment of beta-ketoisothiocyanate with …651Cite
Response of pulse phenol injection on an anaerobic-anoxic-aerobic system.
Chakraborty S, Veeramani H.Bioresour Technol. 2005 May;96(7):761-7. doi: 10.1016/j.biortech.2004.08.008.PMID: 15607188
The synthetic feed contained phenol, cyanide, thiocyanate and ammonia-nitrogen. Anaerobic reactor required 22 days to regain its previous cyanide removal efficiency and the reactor achieved a new steady state in terms of phenol removal. The anoxic reactor achieved its prev …652Cite
Redox buffering of hypochlorous acid by thiocyanate in physiologic fluids.
Ashby MT, Carlson AC, Scott MJ.J Am Chem Soc. 2004 Dec 15;126(49):15976-7. doi: 10.1021/ja0438361.PMID: 15584727
The major antimicrobial products of neutrophilic myeloperoxidase (MPO) in physiologic fluids are hypochlorous acid (HOCl) and hypothiocyanite (OSCN-), and the former is generally believed to be the killing agent. …653Cite
Chandra AK, Ghosh D, Mukhopadhyay S, Tripathy S.Indian J Exp Biol. 2004 Aug;42(8):781-6.PMID: 15573527
Significant increase in thyroid weight as well as higher excretion of thiocyanate and iodine along with marked decrease in thyroid peroxidase activity, T4 and T3 levels were observed in BS fed group. …Extra iodide had reduced the anti-thyroidal effect of BS to an extent …654Cite
Braverman LE, He X, Pino S, Cross M, Magnani B, Lamm SH, Kruse MB, Engel A, Crump KS, Gibbs JP.J Clin Endocrinol Metab. 2005 Feb;90(2):700-6. doi: 10.1210/jc.2004-1821. Epub 2004 Nov 30.PMID: 15572417
Perchlorate (ClO(4)(-)) and thiocyanate (SCN(-)) are potent and nitrate (NO(3)(-)) a weak competitive inhibitor of the thyroid sodium-iodide symporter. …655Cite
Novel thiocyanato complexes with potent cytotoxic and antimicrobial properties.
Hossain MS, Easmin S, Islam MS, Rashid M.J Pharm Pharmacol. 2004 Dec;56(12):1519-25. doi: 10.1211/0022357044913.PMID: 15563758
The aim of the present study was to assess the cytotoxic and antimicrobial properties of seven new thiocyanato complexes: Ni(C(9)H(11)N(2)O)(SCN), Cu(C(9)H(11)N(2)O)(SCN), Pd(C(9)H(11)N(2)O)(SCN), Pt(C(9)H(11)N(2) O) (SCN), K[Ti(C(9)H(11)N(2)O)(SCN)(3)], Au(C(9)H(11)N(2)O) …656Cite
Lemmer K, Mielke M, Pauli G, Beekes M.J Gen Virol. 2004 Dec;85(Pt 12):3805-3816. doi: 10.1099/vir.0.80346-0.PMID: 15557254
Effective reprocessing of surgical instruments ensuring elimination of inadvertent contamination with infectious agents causing transmissible spongiform encephalopathies (TSEs) is essential for the prevention of iatrogenic transmission of Creutzfeldt-Jakob disease (CJD) or …657Cite
[Induction and reversibility of thyroid proliferative changes in suckling rats given thiocyanate].
Soussia L, Ben Hamida F, Guermazi F, Zeghal N.Ann Endocrinol (Paris). 2004 Oct;65(5):451-8. doi: 10.1016/s0003-4266(04)95950-1.PMID: 15550887 French.
Potassium thiocyanate given in the drinking water of pregnant rats led to decreased body weight in their 14-day-old offspring (27%) without altering thyroid weight. …Plasma FT3 and TSH were unchanged after thiocyanate treatment. The biochemical changes were in agr …658Cite
Takahama U, Oniki T.Biochim Biophys Acta. 2004 Nov 18;1675(1-3):130-8. doi: 10.1016/j.bbagen.2004.09.001.PMID: 15535976
An objective of the present study is to elucidate the effects of salivary SCN- and NO2- on the hydroxylation of salicylic acid which was induced by H2O2/Fe(II) and AA/H2O2/Fe(II) systems. Thiocyanate ion inhibited the hydroxylation of salicylic acid by the above systems in …659Cite
Simmons CA, Zilberberg J, Davies PF.Ann Biomed Eng. 2004 Oct;32(10):1453-9. doi: 10.1114/b:abme.0000042360.57960.2b.PMID: 15535062
Endothelial cells were retrieved from fresh tissue by freezing them to a glass substrate, from which they were lysed in guanidine thiocyanate buffer for RNA isolation. Valve endothelial cells isolated by this technique stained positively for CD31 and von Willebrand factor, …660Cite
Chandra AK, Tripathy S, Lahari D, Mukhopadhyay S.Indian J Physiol Pharmacol. 2004 Apr;48(2):219-24.PMID: 15521562
On the spot 242 urine samples were collected from the children to study the iodine and thiocyanate excretion pattern and 108 edible salt samples were collected from the homes of the children to measure iodine level. …The people of the area consume foods from the vegetabl …661Cite
Alberto PC, Marmottini F, Arienti G, Palombari R.Arch Biochem Biophys. 2004 Dec 1;432(1):37-40. doi: 10.1016/j.abb.2004.09.014.PMID: 15519294
S-Nitrosocysteine (CysNO) releases either NO (in the presence of divalent cations) or NO+ (in the presence of chelating agents). NO+ is then transferred to peptides or protein SH groups to form high-mass nitrosothiols. The aim of this work was the development of a specific …662Cite
Konwinski RR, Haddad R, Chun JA, Klenow S, Larson SC, Haab BB, Furge LL.Toxicol Lett. 2004 Nov 28;153(3):343-55. doi: 10.1016/j.toxlet.2004.06.006.PMID: 15454310663Cite
Suzuki E, Kessler M, Montgomery K, Arai AC.Mol Pharmacol. 2004 Dec;66(6):1738-47. doi: 10.1124/mol.104.003038. Epub 2004 Sep 24.PMID: 15448189
This pattern of effects differentiates PPNDS from other compounds such as thiocyanate and up-modulators, which increase agonist binding by enhancing desensitization or slowing deactivation, respectively. …664Cite
Oral broccoli sprouts for the treatment of Helicobacter pylori infection: a preliminary report.
Galan MV, Kishan AA, Silverman AL.Dig Dis Sci. 2004 Aug;49(7-8):1088-90. doi: 10.1023/b:ddas.0000037792.04787.8a.PMID: 15387326 Clinical Trial.665Cite
Salivary analyses and caries increment over 4 years: an approach by cluster analysis.
Jentsch H, Beetke E, Göcke R.Clin Oral Investig. 2004 Sep;8(3):156-60. doi: 10.1007/s00784-004-0263-6. Epub 2004 Apr 15.PMID: 15338312
METHODS: Samples of unstimulated and stimulated whole saliva from 28 young adults (mean age 23.5+/-2.1 years) were analyzed for flow rate, pH and buffer variables, lysozyme, lactoferrin, peroxidase, thiocyanate, secretory immunoglobulin A, and total protein. The decayed, m …666Cite
Nematocidal thiocyanatins from a southern Australian marine sponge Oceanapia sp.
Capon RJ, Skene C, Liu EH, Lacey E, Gill JH, Heiland K, Friedel T.J Nat Prod. 2004 Aug;67(8):1277-82. doi: 10.1021/np049977y.PMID: 15332841
Investigations of a southern Australian marine sponge, Oceanapia sp., have yielded two new beta methyl branched bisthiocyanates, thiocyanatins D1 (3a) and D(2) (3b), along with two new thiocarbamate thiocyanates, thiocyanatins E1 (4a) and E2 (4b). The new thiocyanatins bel …667Cite
Rahmat A, Kumar V, Fong LM, Endrini S, Sani HA.Asia Pac J Clin Nutr. 2004;13(3):308-11.PMID: 15331345 Free article.
Besides that, two research methods used were the ferric thiocyanate (FTC) and thiobarbituric acid (TBA) with absorbance of 500nm and 532nm respectively. …668Cite
[Changes in the fine structure of microbial cells induced by chaotropic salts].
Duda VI, Danilevich VN, Suzina NF, Shorokhova AP, Dmitriev VV, Mokhova ON, Akimov VN.Mikrobiologiia. 2004 May-Jun;73(3):406-15.PMID: 15315236 Russian.
The electron microscopic examination of the thin sections of cells of the yeasts Saccharomyces cerevisiae and Pichia pastoris and the gram-positive bacteria Micrococcus luteus and Bacillus subtilis showed that cell treatment with the chaotropic salts guanidine hydrochloride (6 M) …669Cite
Haukioja A, Ihalin R, Loimaranta V, Lenander M, Tenovuo J.J Med Microbiol. 2004 Sep;53(Pt 9):855-860. doi: 10.1099/jmm.0.45548-0.PMID: 15314191
The sensitivity of H. pylori to physiological concentrations of lactoperoxidase and its salivary substrate thiocyanate, and different amounts of hydrogen peroxide (H(2)O(2)) was investigated in buffer and in human whole saliva. …670Cite
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.
Myzak MC, Karplus PA, Chung FL, Dashwood RH.Cancer Res. 2004 Aug 15;64(16):5767-74. doi: 10.1158/0008-5472.CAN-04-1326.PMID: 15313918671Cite
Plantin-Carrenard E, Cattan F, Aurengo A, Dumérat B, Foglietti MJ, Beaudeux JL.Ann Biol Clin (Paris). 2004 Jul-Aug;62(4):456-61.PMID: 15297242 Free article. French.672Cite
El-Assiery SA, Sayed GA, Fouda A.Acta Pharm. 2004 Jun;54(2):143-50.PMID: 15274757
Compound 2 was used as the key intermediate to prepare the pyrazolo-pyrido-pyrimidine derivatives through its reaction with formic acid, formamide-formic acid-DMF, ammonium thiocyanate or reaction with triethyl orthoformate followed by cyclization with hydrazine hydrate. . …673Cite
Effect of co-administration of cassava (Manihot esculenta Crantz) rich diet and alcohol in rats.
Boby RG, Indira M.Indian J Physiol Pharmacol. 2004 Jan;48(1):41-50.PMID: 15270368
The pyruvate content in the blood increased while the lactate content, lactate/pyruvate ratio and the activity of LDH decreased in the blood due to co-administration. The blood cyanide content, serum thiocyanate content and the activities of rhodanase and beta-glucuronidas …674Cite
Peng ZG, Hidajat K, Uddin MS.Colloids Surf B Biointerfaces. 2004 Jun 1;35(3-4):169-74. doi: 10.1016/j.colsurfb.2004.03.010.PMID: 15261028675Cite
Mechanism of sulforaphane-induced cell cycle arrest and apoptosis in human colon cancer cells.
Parnaud G, Li P, Cassar G, Rouimi P, Tulliez J, Combaret L, Gamet-Payrastre L.Nutr Cancer. 2004;48(2):198-206. doi: 10.1207/s15327914nc4802_10.PMID: 15231455676Cite
[Iodine levels in food and soil in different regions in Cameroon].
Taga I, Sameza ML, Kayo AV, Ngogang J.Sante. 2004 Jan-Mar;14(1):11-5.PMID: 15217739 Free article. French.
They are often the consequence of insufficient iodine intake and/or the effect of thiocyanate in foods such as cassava; this chemical inhibits iodine fixation by the thyroid gland. …Iodine content in foods and soils was assessed by the catalytic destructive testing of …677Cite
Thiocyanate catalyzes myeloperoxidase-initiated lipid oxidation in LDL.
Exner M, Hermann M, Hofbauer R, Hartmann B, Kapiotis S, Gmeiner B.Free Radic Biol Med. 2004 Jul 15;37(2):146-55. doi: 10.1016/j.freeradbiomed.2004.04.039.PMID: 15203186
Chloride is supposed to be the major substrate for MPO, generating reactive hypochlorous acid (HOCl), modifying LDL. The pseudo-halide thiocyanate (SCN-) has been shown to be a suitable substrate for MPO, forming reactive HOSCN/SCN*. …678Cite
Akindahunsi AA, Salawu SO, Adu OC.Nutr Health. 2004;17(4):297-307. doi: 10.1177/026010600401700405.PMID: 15174737
The parameters determined include iodine, thiocyanate, chloride, nitrate, calcium, magnesium hardness, calcium hardness, total hardness, and total coliform counts in water, sediment and/or fish (flesh and serum). …Only the large sized fish of Ogbese recorded a value of 5 …679Cite
Distribution of hepatitis C virus genotypes in patients with chronic hepatitis C infection in India.
Singh S, Malhotra V, Sarin SK.Indian J Med Res. 2004 Apr;119(4):145-8.PMID: 15147119
HCV RNA was extracted from the serum by standard guanidinium thiocyanate method. Following reverse transcription and amplification, the HCV genotypes were determined by line probe assay (INNO-LiPA HCV II). …680Cite
Antikinetoplastid activity of 3-aryl-5-thiocyanatomethyl-1,2,4-oxadiazoles.
Cottrell DM, Capers J, Salem MM, DeLuca-Fradley K, Croft SL, Werbovetz KA.Bioorg Med Chem. 2004 Jun 1;12(11):2815-24. doi: 10.1016/j.bmc.2004.03.054.PMID: 15142541
Formation of the oxadiazole ring was accomplished through the reaction of benzamidoximes with acyl chlorides, while the thiocyanate group was inserted by reacting the appropriate 5-halomethyl oxadiazole with ammonium thiocyanate. …These results indicate that aroma …681Cite
Touch V, Hayakawa S, Yamada S, Kaneko S.Int J Food Microbiol. 2004 Jun 1;93(2):175-83. doi: 10.1016/j.ijfoodmicro.2003.11.004.PMID: 15135956
The purified protein was used to catalyze the oxidation of thiocyanate by H2O2 in an antibacterial system (LPO system). The LPO system was used to inactivate or inhibit Salmonella enteritidis in tomato juice, carrot juice, milk, liquid whole egg, and chicken skin extract u …682Cite
Role of thiocyanate, bromide and hypobromous acid in hydrogen peroxide-induced apoptosis.
Wagner BA, Reszka KJ, McCormick ML, Britigan BE, Evig CB, Burns CP.Free Radic Res. 2004 Feb;38(2):167-75. doi: 10.1080/10715760310001643302.PMID: 15104210
We now report that when chloride is replaced by the pseudohalide thiocyanate, there is little or no H2O2-induced apoptosis. Furthermore, thiocyanate inhibits H2O2-induced apoptosis when chloride is present at physiological concentrations, and this occurs at thioc …683Cite
Jacobsen N, Nielsen PS, Jeffares DC, Eriksen J, Ohlsson H, Arctander P, Kauppinen S.Nucleic Acids Res. 2004 Apr 19;32(7):e64. doi: 10.1093/nar/gnh056.PMID: 15096560 Free PMC article.
Poly(A)+ RNA was isolated directly from 4 M guanidine thiocyanate-lysed Caenorhabditis elegans worm extracts as well as from lysed human K562 and vincristine-resistant K562/VCR leukemia cells using LNA_2.T oligonucleotide as an affinity probe, in which every second thymidi …684Cite
The efficiency of different salts to screen charge interactions in proteins: a Hofmeister effect?
Perez-Jimenez R, Godoy-Ruiz R, Ibarra-Molero B, Sanchez-Ruiz JM.Biophys J. 2004 Apr;86(4):2414-29. doi: 10.1016/S0006-3495(04)74298-8.PMID: 15041679 Free PMC article.
To this end, we have carried out an energetic characterization of the effect of NaCl (a nondenaturing salt), guanidinium chloride (a denaturing salt), and guanidinium thiocyanate (a stronger denaturant) on the stability of the wild-type form and a T14K variant of Escherich …685Cite
Ragab GH, Amin AS.Spectrochim Acta A Mol Biomol Spectrosc. 2004 Mar;60(4):973-8. doi: 10.1016/S1386-1425(03)00327-5.PMID: 15036111686Cite
Xu J, Hu Q.J Agric Food Chem. 2004 Mar 24;52(6):1759-63. doi: 10.1021/jf0349836.PMID: 15030242
Selenium fertilizer was foliar applied to determine the effects of antioxidant activity of selenium-enriched rice assessed by alpha,alpha-diphenyl-beta-picylhydrazyl (DPPH) radical scavenging and the ferric thiocyanate (FTC) method. Results showed that selenium concentrati …687Cite
Residual goitre in the postiodization phase: iodine status, thiocyanate exposure and autoimmunity.
Marwaha RK, Tandon N, Gupta N, Karak AK, Verma K, Kochupillai N.Clin Endocrinol (Oxf). 2003 Dec;59(6):672-81. doi: 10.1046/j.1365-2265.2003.01895.x.PMID: 14974907
MEASUREMENTS: Urinary iodine (wet ashing method), urinary thiocyanate (colourimetric method), serum thyroxine [in-house radioimmunoassay (RIA)], serum TSH (IRMA), antithyroid microsomal and antithyroglobulin antibodies (haemagglutination method) were estimated. …TMA posi …688Cite
Kudoh K, Matsumoto M, Onodera S, Takeda Y, Ando K, Shiomi N.J Nutr Sci Vitaminol (Tokyo). 2003 Dec;49(6):451-5. doi: 10.3177/jnsv.49.451.PMID: 14974739
The Po-P obtained by proteolysis with Amano P and pancreatin inhibited linoleic acid oxidation either by 83%, at its coexistent 0.005% in a ferric thiocyanate assay system or by 32% at its coexistent 0.0002% in a beta-carotene decolorization assay system. …689Cite
Thiocyanate overload and thyroid disease.
Erdogan MF.Biofactors. 2003;19(3-4):107-11. doi: 10.1002/biof.5520190302.PMID: 14757960 Review.
Thiocyanate [SCN-] is a complex anion which is a potent inhibitor of iodide transport. It is the detoxification product of cyanide and can easily be measured in body fluids. …In this mini-review, issues regarding thiocyanate overload and thyroid disease will be su …690Cite
Fite A, Dykhuizen R, Litterick A, Golden M, Leifert C.Antimicrob Agents Chemother. 2004 Feb;48(2):655-8. doi: 10.1128/AAC.48.2.655-658.2004.PMID: 14742231 Free PMC article.
In this study, we showed that the reducing agents ascorbic acid and glutathione reduced the activity of acidified nitrite against Yersinia enterocolitica (P < 0.001). In contrast, iodide and thiocyanate increased the antimicrobial activity (P < 0.001),…691Cite
Folding and association of an extremely stable dimeric protein from Sulfolobus islandicus.
Zeeb M, Lipps G, Lilie H, Balbach J.J Mol Biol. 2004 Feb 6;336(1):227-40. doi: 10.1016/j.jmb.2003.12.003.PMID: 14741218692Cite
Guo Q, Detweiler CD, Mason RP.J Biol Chem. 2004 Mar 26;279(13):13272-83. doi: 10.1074/jbc.M310034200. Epub 2004 Jan 14.PMID: 14724284 Free article.
The level of this nitrone adduct was decreased significantly by azide, catalase, ascorbate, iodide, thiocyanate, phenol, or nitrite. However, its formation was unaffected by chemical modification of free cysteine, tyrosine, and tryptophan residues on LPO. …Its formation …693Cite
Iodine nutrition in breast-fed infants is impaired by maternal smoking.
Laurberg P, Nøhr SB, Pedersen KM, Fuglsang E.J Clin Endocrinol Metab. 2004 Jan;89(1):181-7. doi: 10.1210/jc.2003-030829.PMID: 14715847
Smoking mothers had significantly higher serum levels of thiocyanate, which may competitively inhibit the sodium-iodide symporter responsible for iodide transport in the lactating mammary gland. …694Cite
Whittier CA, Horne W, Slenning B, Loomis M, Stoskopf MK.J Virol Methods. 2004 Mar 1;116(1):11-7. doi: 10.1016/j.jviromet.2003.10.003.PMID: 14715302
A commercially available viral RNA extraction kit was used to isolate nucleic acids from captive gorilla fecal samples seeded with rotavirus and stored in ethanol, formalin, a commercial RNA preservation solution, guanidine thiocyanate buffer (GT), and samples dried in tub …695Cite
Chandra S, Sangeetika X.Spectrochim Acta A Mol Biomol Spectrosc. 2004 Jan;60(1-2):147-53. doi: 10.1016/s1386-1425(03)00220-8.PMID: 14670471
The complexes of macrocylic ligand with a general composition M(H(2)L(4))X(2) [where M=Cu(II) or Ni(II); H(2)L(4)=1,2,5,6,8,11-hexaazacyclo dodeca-7,12-dithione-2,4,8,10-tetraene; X= Cl(-), NO(3)(-), (1)/(2)SO(4)(2-)] and ML(4) (where metal salt used to synthesize complex is copp …696Cite
Effect of cigarette smoke on oral peroxidase activity in human saliva: role of hydrogen cyanide.
Klein I, Nagler RM, Toffler R, van Der Vliet A, Reznick AZ.Free Radic Biol Med. 2003 Dec 1;35(11):1448-52. doi: 10.1016/j.freeradbiomed.2003.08.001.PMID: 14642392
The term oral peroxidase (OPO) is used here to denote the total activity of both peroxidase species. Using the 2-nitrobenzoic acid-thiocyanate assay, OPO activity was measured in the saliva of nonsmokers after exposure to gas-phase cigarette smoke (CS) in an in vitro syste …697Cite
Haristoy X, Angioi-Duprez K, Duprez A, Lozniewski A.Antimicrob Agents Chemother. 2003 Dec;47(12):3982-4. doi: 10.1128/AAC.47.12.3982-3984.2003.PMID: 14638516 Free PMC article.698Cite
Quigley WW, Bramanti E, Staggemeier BA, Miller KE, Nabi A, Skogerboe KJ, Synovec RE.Anal Bioanal Chem. 2004 Jan;378(1):134-43. doi: 10.1007/s00216-003-2323-1. Epub 2003 Nov 14.PMID: 14618291
A drop-based dynamic surface-tension detector (DSTD) has been used to study the dynamic surface tension behavior of proteins denatured in guanidine thiocyanate (GndSCN). The dynamic surface tension at the air-liquid interface is obtained by measuring the internal pressure …699Cite
Kim BR, Hu R, Keum YS, Hebbar V, Shen G, Nair SS, Kong AN.Cancer Res. 2003 Nov 1;63(21):7520-5.PMID: 14612554700Cite
[Thiocyanate and central nervous system maturation of young mice].
Ben Hamida F, Soussia L, Guermazi F, Zeghal N.Ann Endocrinol (Paris). 2003 Oct;64(4):268-76.PMID: 14595238 French.
Potassium thiocyanate, given to the drink of pregnant mothers provoked a body weight decrease of 14 day-old mice (-18%), without perturbations of cerebrum and cerebellum weights. …Modifications of biochemical parameters confirmed the histological aspects of hypothyroid m …701Cite
Nucleic acid purification using microfabricated silicon structures.
Cady NC, Stelick S, Batt CA.Biosens Bioelectron. 2003 Oct 30;19(1):59-66. doi: 10.1016/s0956-5663(03)00123-4.PMID: 14558999702Cite
Mukhufhi N, Irons PC, Michel A, Peta F.Theriogenology. 2003 Oct 15;60(7):1269-78. doi: 10.1016/s0093-691x(03)00138-9.PMID: 14511781
The objectives of this study were to determine the detection limit of a PCR test for Tritrichomonas foetus, to investigate the effect of sampling method, guanidinium thiocyanate (GuSCN), and sample storage, and to confirm the accuracy of the test on field samples. …703Cite
Rahmat A, Kumar V, Fong LM, Endrini S, Sani HA.Asia Pac J Clin Nutr. 2003;12(3):292-5.PMID: 14505992 Free article.
Besides that, two research methods used were the ferric thiocyanate (FTC) and thiobarbituric acid (TBA) with absorbance of 500 nm and 532 nm respectively. …704Cite
Contempré B, de Escobar GM, Denef JF, Dumont JE, Many MC.Endocrinology. 2004 Feb;145(2):994-1002. doi: 10.1210/en.2003-0886. Epub 2003 Sep 18.PMID: 14500569 Free article.
Thyroid destruction leading to endemic myxoedematous cretinism is highly prevalent in central Africa, where iodine (I) and selenium (SE) deficiencies as well as thiocyanate (SCN) overload are combined. All three factors have been studied experimentally in the etiology of t …705Cite
Nitrite-catalase interaction as an important element of nitrite toxicity.
Titov VY, Petrenko YM.Biochemistry (Mosc). 2003 Jun;68(6):627-33. doi: 10.1023/a:1024609624652.PMID: 12943506
It was established that nitrite in the presence of chloride, bromide, and thiocyanate decreases the rate of hydrogen peroxide decomposition by catalase. The decrease was recorded by the permanganatometric method and by a method of dynamic calorimetry. …However, in the ab …706Cite
Synthesis of isothiocyanate-derived mercapturic acids.
Vermeulen M, Zwanenburg B, Chittenden GJ, Verhagen H.Eur J Med Chem. 2003 Jul-Aug;38(7-8):729-37. doi: 10.1016/s0223-5234(03)00141-7.PMID: 12932904707Cite
Specific ion effects: why the properties of lysozyme in salt solutions follow a Hofmeister series.
Boström M, Williams DR, Ninham BW.Biophys J. 2003 Aug;85(2):686-94. doi: 10.1016/S0006-3495(03)74512-3.PMID: 12885620 Free PMC article.
Why for instance does the use of two different monovalent salts, potassium thiocyanate and potassium chloride, produce such different results? One important and previously neglected source of ion specificity is the ionic dispersion potential that acts between each ion and …708Cite
Arias-Bouda LM, Kuijper S, Van der Werf A, Nguyen LN, Jansen HM, Kolk AH.Clin Diagn Lab Immunol. 2003 Jul;10(4):702-9. doi: 10.1128/cdli.10.4.702-709.2003.PMID: 12853408 Free PMC article.
Antibody avidity was measured by an enzyme-linked immunosorbent assay with thiocyanate elution. Avidity indices and serum levels of immunoglobulin G to M. tuberculosis were determined for 22 patients with pulmonary tuberculosis before and during treatment and for 24 patien …709Cite
Chemoprevention of cancerogenesis–the role of sulforaphane.
Sołowiej E, Kasprzycka-Guttman T, Fiedor P, Rowinśki W.Acta Pol Pharm. 2003 Jan-Feb;60(1):97-100.PMID: 12848375 Free article.
Isothiocyanates are a group of naturally occurring compounds with interesting medical properties, such as antimicrobial, antioxidant and antitumor activities. In our work we were trying to present the tumoricidal activity of new synthesized derivatives of one isothiocyanat …710Cite
Bramanti E, Ferri F, Sortino C, Onor M, Raspi G, Venturini M.Biopolymers. 2003 Jul;69(3):293-300. doi: 10.1002/bip.10366.PMID: 12833256711Cite
Loksha YM, El-Badawi MA, El-Barbary AA, Pedersen EB, Nielsen C.Arch Pharm (Weinheim). 2003 Jun;336(3):175-80. doi: 10.1002/ardp.200390017.PMID: 12822183
Treatment of 2a-d with aqueous potassium thiocyanate afforded 1, 3-imidazole-2-thiones 3a-d which were alkylated with methyl iodide to give 2-methylsulfanyl-1H-imidazoles 4a-d with 4-benzyl/4-cyclohexylmethyl and 5-ethyl/5-isopropyl substituents. …712Cite
Antiamoebic activity of benzyl glucosinolate from Lepidium virginicum.
Calzada F, Barbosa E, Cedillo-Rivera R.Phytother Res. 2003 Jun;17(6):618-9. doi: 10.1002/ptr.1210.PMID: 12820228
In a continuation of our search for potential antiprotozoal agents from plants, we found that a crude extract from the roots of Lepidium virginicum exhibited antiprotozoal activity against Entamoeba histolytica trophozoites (IC(50) of 100.1 micro g/mL). …713Cite
Effect of hormone replacement therapy on lacrimal fluid peroxidase activity in woman.
Marcozzi G, Liberati V, Madia F, Pizzinga A, de Feo G.Maturitas. 2003 Jul 25;45(3):225-9. doi: 10.1016/s0378-5122(03)00146-4.PMID: 12818468 Clinical Trial.
OBJECTIVE: Lacrimal fluid peroxidase (POD) is an antioxidant and antimicrobial enzyme involved in the protection of the ocular surface. Our recent findings showed the existence of significant cyclic variations in POD activity that were positively correlated with those of 1 …714Cite
Tao SC, Li Y, Liu YH, Ma XM, Cheng J.Biotechniques. 2003 Jun;34(6):1260-2. doi: 10.2144/03346mt01.PMID: 12813894 Free article. No abstract available.715Cite
Effects of lactoperoxidase and hydrogen peroxide on rheological properties of yoghurt.
Ozer B, Grandison A, Robinson R, Atamer M.J Dairy Res. 2003 May;70(2):227-32. doi: 10.1017/s0022029903006149.PMID: 12800877716Cite
Old MO, Martinez CV, Kwock D, Garcia J, Martin G, Chan C, Maldonado YA.J Virol Methods. 2003 Jun 30;110(2):193-200. doi: 10.1016/s0166-0934(03)00133-2.PMID: 12798248
To permit rapid and efficient detection of Sabin poliovirus type 3 from human fecal samples, we developed a guanidine thiocyanate (GuSCN) extraction and reverse transcriptase polymerase chain reaction (RT-PCR) method. …717Cite
Determination of antifungal proteins in soil by liquid chromatography.
Bolygo E, Ricketts D, Moffatt F, Jessop M, Attenborough S.Anal Bioanal Chem. 2003 Jul;376(5):701-5. doi: 10.1007/s00216-003-1955-5. Epub 2003 May 24.PMID: 12768264
A liquid chromatography method was developed for the determination of antifungal/antimicrobial proteins Rs-AFP1 and Dm-AMP1 in sandy loam soils. The extraction of these highly basic proteins was achieved by mechanical shaking with aqueous Tris buffer pH 9 containing guanid …718Cite
Further studies on spot tests and microcrystal tests for identification of cocaine.
Swiatko J, De Forest PR, Zedeck MS.J Forensic Sci. 2003 May;48(3):581-5.PMID: 12762528
Seventeen chemical species were tested using three different spot tests (Wagner, Marquis, and cobalt thiocyanate followed by stannous chloride reactions) and two microcrystal tests (gold chloride and platinic chloride) to determine whether the results could be differentiat …719Cite
Urbina JA, Concepcion JL, Montalvetti A, Rodriguez JB, Docampo R.Antimicrob Agents Chemother. 2003 Jun;47(6):2047-50. doi: 10.1128/AAC.47.6.2047-2050.2003.PMID: 12760897 Free PMC article.
We investigated the molecular basis of the activity of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the etiological agent of Chagas’ disease. We found that growth inhibition of T. cruzi epimastigotes induced by this compound was associated with a red …720Cite
Surface thiocyanation of plasticized poly(vinyl chloride) and its effect on bacterial adhesion.
James NR, Jayakrishnan A.Biomaterials. 2003 Jun;24(13):2205-12. doi: 10.1016/s0142-9612(03)00022-x.PMID: 12699656
In order to examine whether a covalently bound and immobilized thiocyanate group on a biomaterial surface is still effective as a bactericide, plasticized poly(vinyl chloride) (PVC) was thiocyanated using sodium thiocyanate in the presence of a phase transfer …721Cite
Identification of an antioxidant, ethyl protocatechuate, in peanut seed testa.
Huang SC, Yen GC, Chang LW, Yen WJ, Duh PD.J Agric Food Chem. 2003 Apr 9;51(8):2380-3. doi: 10.1021/jf0210019.PMID: 12670184
The antioxidant activity of peanut seed testa was studied in the linoleic acid model system by using the ferric thiocyanate method. Among the five organic solvent extracts, the ethanolic extracts of peanut seed testa (EEPST) produced higher yields and stronger antioxidant …722Cite
Conductometric and indirect AAS determination of antimalarials.
Amin AS, Issa YM.J Pharm Biomed Anal. 2003 Mar 26;31(4):785-94. doi: 10.1016/s0731-7085(02)00334-5.PMID: 12644205
Two methods are described for the determination of amodiaquine hydrochloride, chloroquine phosphate and primaquine phosphate, based on the formation of their ion-associates with [Cd(2+), Co(2+), Mn(2+) and Zn(2+)] thiocyanate, ammonium reineckate and/or sodium cobaltinitri …723Cite
Accuracy of BRT and Delvotest microbial inhibition tests as affected by composition of ewe’s milk.
Althaus R, Torres A, Peris C, Beltran MC, Fernandez N, Molina MP.J Food Prot. 2003 Mar;66(3):473-8. doi: 10.4315/0362-028x-66.3.473.PMID: 12636303 Free article.
Moreover, Delvotest-positive samples exhibited thiocyanate concentrations higher than those of Delvotest-negative samples (8.18 mg/liter versus 6.85 mg/liter). Further analyses are needed to confirm the possible presence of antimicrobial residues in this particular …724Cite
Suzuki T, Ohshima H.Chem Pharm Bull (Tokyo). 2003 Mar;51(3):301-4. doi: 10.1248/cpb.51.301.PMID: 12612415 Free article.
The influence of fluoride (F(-)), bromide (Br(-)), iodide (I(-)), thiocyanate (SCN(-)) and nitrite (NO(2)(-)) on the reaction of a myeloperoxidase-H(2)O(2)-Cl(-) system with a nucleoside mixture was studied. …725Cite
Functional expression of sodium iodide symporter (NIS) in human breast cancer tissue.
Upadhyay G, Singh R, Agarwal G, Mishra SK, Pal L, Pradhan PK, Das BK, Godbole MM.Breast Cancer Res Treat. 2003 Jan;77(2):157-65. doi: 10.1023/a:1021321409159.PMID: 12602914
The in vivo iodine transport ability was confirmed by scintigraphy. Unlike thyroid, perchlorate and thiocyanate do not inhibit iodine transport in breast tumors. The presence of iodinated proteins suggests the longer retention time. …726Cite
Post-secretory fate of host defence components in mucus.
Salathe M, Forteza R, Conner GE.Novartis Found Symp. 2002;248:20-6; discussion 27-37, 277-82.PMID: 12568486 Review.
Airway mucus is a complex mixture of secretory products that provide a multifaceted defence against infection. Among many antimicrobial substances, mucus contains a peroxidase identical to milk lactoperoxidase (LPO) that is produced by goblet cells and submucosal glands. A …727Cite
Samadi-Maybodi A, Ourad SM.Luminescence. 2003 Jan-Feb;18(1):42-8. doi: 10.1002/bio.705.PMID: 12536379728Cite
High-quality genomic DNA from human whole blood and mononuclear cells.
Malferrari G, Monferini E, DeBlasio P, Diaferia G, Saltini G, Del Vecchio E, Rossi-Bernardi L, Biunno I.Biotechniques. 2002 Dec;33(6):1228-30. doi: 10.2144/02336bm09.PMID: 12503304 Free article. No abstract available.729Cite
Rosin M, Kramer A, Bradtke D, Richter G, Kocher T.J Clin Periodontol. 2002 Dec;29(12):1086-91. doi: 10.1034/j.1600-051x.2002.291207.x.PMID: 12492909 Clinical Trial.
OBJECTIVES: The aim of the study was to compare the gingival health benefits of a thiocyanate/carbamide peroxide toothpaste to that of a triclosan toothpaste in home use. …CONCLUSION: To conclude, this study seems to verify that in normal home use, a toothpaste containin …730Cite
Comparison of DNA and RNA extraction methods for mummified tissues.
Konomi N, Lebwohl E, Zhang D.Mol Cell Probes. 2002 Dec;16(6):445-51. doi: 10.1006/mcpr.2002.0441.PMID: 12490146
Twelve mummy specimens were analyzed with 9 different nucleic acid extraction methods, including guanidium thiocyanate (GTC) and proteinase K/detergent based methods prepared in our laboratory or purchased. …731Cite
Laurberg P, Andersen S, Knudsen N, Ovesen L, Nøhr SB, Bülow Pedersen I.Thyroid. 2002 Oct;12(10):897-902. doi: 10.1089/105072502761016520.PMID: 12487772 Review.
Second, iodine in dairy products provides a considerable part of iodine intake in many populations. Thiocyanate from rapeseed feeding of cows decreases milk iodine content, probably by competitive inhibition of NIS in the mammary gland. Alterations in feeding of dairy cows …732Cite
The lactoperoxidase system increases efficacy of high-pressure inactivation of foodborne bacteria.
García-Graells C, Van Opstal I, Vanmuysen SC, Michiels CW.Int J Food Microbiol. 2003 Mar 25;81(3):211-21. doi: 10.1016/s0168-1605(02)00263-5.PMID: 12485747
The inactivation of eight different bacteria comprising Escherichia coli LMM1010 and MG1655, respectively a pressure-resistant strain and the corresponding wild-type, Salmonella Typhimurium, Pseudomonas fluorescens, Staphylococcus aureus, Enterococcus faecalis, Listeria innocua a …733Cite
Quantitative determination of salivary components in the pellicle on PMMA denture base material.
Göcke R, Gerath F, von Schwanewede H.Clin Oral Investig. 2002 Dec;6(4):227-35. doi: 10.1007/s00784-002-0176-1. Epub 2002 Oct 15.PMID: 12483238
The solution was analysed for total protein, alpha-amylase, total proteases, protease inhibitors, secretory immunoglobulin A, immunoglobulin G, peroxidases, thiocyanate, lysozyme, and calcium content. All investigated salivary components could be found unequivocally in the …734Cite
Knudsen N, Bülow I, Laurberg P, Perrild H, Ovesen L, Jørgensen T.J Endocrinol. 2002 Dec;175(3):571-6. doi: 10.1677/joe.0.1750571.PMID: 12475368
The observed associations seem to be explainable by the blocking of iodine uptake and organification in the thyroid by thiocyanate, a degradation product of cyanide in tobacco smoke….735Cite
Lactoperoxidase and hydrogen peroxide metabolism in the airway.
Conner GE, Salathe M, Forteza R.Am J Respir Crit Care Med. 2002 Dec 15;166(12 Pt 2):S57-61. doi: 10.1164/rccm.2206018.PMID: 12471090 Review.
This enzyme uses H2O2 to oxidize the anion thiocyanate to an antibiotic compound that prevents growth of bacteria, fungi, and viruses. …736Cite
Hydrogen peroxide-scavenging properties of normal human airway secretions.
El-Chemaly S, Salathe M, Baier S, Conner GE, Forteza R.Am J Respir Crit Care Med. 2003 Feb 1;167(3):425-30. doi: 10.1164/rccm.200206-531OC. Epub 2002 Nov 15.PMID: 12446267
Fourfold diluted secretions showed only nonenzymatic scavenging activity, but the addition of thiocyanate to these samples (0.4 mM; substrate for lactoperoxidase) restored their ability to scavenge H2O2. …737Cite
Evaluation of the effectiveness of salt iodization status in Tripura, north east India.
Chandra AK, Ray I.Indian J Med Res. 2002 Jan;115:22-7.PMID: 12424934
The iodine content of salt collected from households was tested by iodometric titration, urinary iodine was measured by dry ashing method and thiocyanate by oxidising bromine and then developing colour by benzedine hydrochloride. RESULTS: Urinary iodine level was measured …738Cite
Literature review–efficacy of various disinfectants against Legionella in water systems.
Kim BR, Anderson JE, Mueller SA, Gaines WA, Kendall AM.Water Res. 2002 Nov;36(18):4433-44. doi: 10.1016/s0043-1354(02)00188-4.PMID: 12418646 Review.
For chemical methods, disinfectants used were metal ions (copper and silver), oxidizing agents (halogen containing compounds [chlorine, bromine, iodine, chlorine dioxide, chloramines, and halogenated hydantoins], ozone, and hydrogen peroxide), non-oxidizing agents ( …739Cite
Antioxidant property of an ethanol extract of the stem of Opuntia ficus-indica var. saboten.
Lee JC, Kim HR, Kim J, Jang YS.J Agric Food Chem. 2002 Oct 23;50(22):6490-6. doi: 10.1021/jf020388c.PMID: 12381138
The ethanol extract exhibited a concentration-dependent inhibition of linoleic acid oxidation in a thiocyanate assay system. In addition, the OFS extract showed dose-dependent free-radical scavenging activity, including DPPH radicals, superoxide anions (O(2)(*-)), and hydr …740Cite
Protease-sensitive scrapie prion protein in aggregates of heterogeneous sizes.
Tzaban S, Friedlander G, Schonberger O, Horonchik L, Yedidia Y, Shaked G, Gabizon R, Taraboulos A.Biochemistry. 2002 Oct 22;41(42):12868-75. doi: 10.1021/bi025958g.PMID: 12379130741Cite
Fonteh FA, Grandison AS, Lewis MJ.J Dairy Res. 2002 Aug;69(3):401-9. doi: 10.1017/s0022029902005538.PMID: 12369411
Lactoperoxidase activity and thiocyanate content were monitored in the milks of seven individual cows and six goats during lactation. …Therefore the exogenous supply of thiocyanate and hydrogen peroxide needed to activate the lactoperoxidase system for raw milk pr …742Cite
Aramrattana A, Limpijarnkit L, Leelapat P, Sriphrapradang A, Mangklabruks A, Pruenglampoo S, Vachiranakorn J, Rajatanavin R.J Med Assoc Thai. 2002 Jul;85(7):831-8.PMID: 12296417
Urine samples were collected for measuring iodine and thiocyanate levels. From 653 children, 105 and 13 were found to have grade 1 and 2 goiter status, respectively. …Multivariate analysis showed that hilltribe minorities had a 2.09 times higher risk of endemic goiter th …743Cite
Reaction of lactoperoxidase compound I with halides and thiocyanate.
Furtmüller PG, Jantschko W, Regelsberger G, Jakopitsch C, Arnhold J, Obinger C.Biochemistry. 2002 Oct 1;41(39):11895-900. doi: 10.1021/bi026326x.PMID: 12269834
Lactoperoxidase (LPO) is found in mucosal surfaces and exocrine secretions, including milk, tears, and saliva, and has physiological significance in antimicrobial defense which involves (pseudo-) halide oxidation. This study for the first time presents transient kinetic me …744Cite
González-Rodríguez J, Pérez-Juan P, Luque De Castro MD.Anal Bioanal Chem. 2002 Sep;374(1):120-5. doi: 10.1007/s00216-002-1432-6. Epub 2002 Aug 7.PMID: 12207252 Free article.
Iron is determined by an existing method based on reaction with thiocyanate in acidic medium and monitoring at 508 nm. After optimisation by either the univariate or multivariate approaches, as required, the linear range was established for methanol (4-1000 mg L(-1)) and i …745Cite
Ma F, Zhao W, Kudo M, Aoki K, Misumi J.Toxicol In Vitro. 2002 Oct;16(5):531-7. doi: 10.1016/s0887-2333(02)00045-0.PMID: 12206820
VacA causes vacuolation of cultured cells such as HeLa cells. Iodine, nitrite, sodium chloride, thiocyanate and fungus toxin sterigmatocystin are universally present in nature and could possibly be related to carcinogenesis of the stomach. …Formation of large vacuoles wa …746Cite
Elhalem E, Bailey BN, Docampo R, Ujváry I, Szajnman SH, Rodriguez JB.J Med Chem. 2002 Aug 29;45(18):3984-99. doi: 10.1021/jm0201518.PMID: 12190320
As a continuation of our project aimed at the search for new and safe chemotherapeutic and chemoprophylactic agents against American trypanosomiasis (Chagas’ disease), several drugs structurally related to 4-phenoxyphenoxyethyl thiocyanate (4) were designed, synthes …747Cite
Schmedt Auf Der Günne H, Tenhagen BA, Kutzer P, Forderung D, Heuwieser W.Dtsch Tierarztl Wochenschr. 2002 Jul;109(7):300-5.PMID: 12161968 German.
Lactoferrin, lysozyme and the lactoperoxidase-thiocyanate-peroxide-system are naturally occurring antimicrobial components of milk. The objective of this study was to examine, whether these components were responsible for negative results, when mastitis milk is cult …748Cite
Efficient isolation of total RNA from antibiotic-producing bacterium Amycolatopsis mediterranei.
Yao Y, Zhang W, Jiao R, Zhao G, Jiang W.J Microbiol Methods. 2002 Oct;51(2):191-5. doi: 10.1016/s0167-7012(02)00078-7.PMID: 12133611
In this report, we described a new method for RNA isolation using the combination of LiCl, urea and guanidinium thiocyanate to disrupt the cell wall of Amycolatopsis. Compared with earlier published RNA isolation methods, the method gave higher yields of pure and intact RN …749Cite
Mutagenicity of sulfoscanate: a comparative study.
Juneja TR, Talukdar A, Gupta RL.Mutat Res. 2002 Jul 25;518(2):155-61. doi: 10.1016/s1383-5718(02)00104-3.PMID: 12113767750Cite
[Antimicrobial activity of myeloperoxidase from neutrophil peroxisome].
But PG, Murav’ev RA, Fomina VA, Rogovin VV.Izv Akad Nauk Ser Biol. 2002 May-Jun;(3):266-70.PMID: 12071050 Review. Russian.
Myeloperoxidase plays the key role in antimicrobial oxygen-dependent activity of neutrophils. This heme-containing enzyme catalyzes HOCl formation from H2O2 and Cl-. HOCl is a strong oxidation agent produced at the significant level by neutrophils. Myeloperoxidase easily o …751Cite
Water contributes actively to the rapid crossing of a protein unfolding barrier.
Jacob MH, Saudan C, Holtermann G, Martin A, Perl D, Merbach AE, Schmid FX.J Mol Biol. 2002 May 3;318(3):837-45. doi: 10.1016/S0022-2836(02)00165-1.PMID: 12054827
At low concentrations of urea or guanidinium thiocyanate, Delta V(++)(UN) decreases significantly, suggesting that compact unfolded forms become populated under these conditions….752Cite
Mares D, Romagnoli C, Tosi B, Benvegnù R, Bruni A, Vicentini CB.Fungal Genet Biol. 2002 Jun;36(1):47-57. doi: 10.1016/S1087-1845(02)00003-8.PMID: 12051894
The antifungal activity of 3-methyl-5-aminoisoxazole-4-thiocyanate, a new azole derivative, was studied on the dermatophyte Epidermophyton floccosum. …753Cite
Lactoperoxidase inhibits glucosyltransferases from Streptococcus mutans in vitro.
Korpela A, Yu X, Loimaranta V, Lenander-Lumikari M, Vacca-Smith A, Wunder D, Bowen WH, Tenovuo J.Caries Res. 2002 Mar-Apr;36(2):116-21. doi: 10.1159/000057869.PMID: 12037368
This study examines the possible effect of the antimicrobial peroxidase system on the activity of streptococcal glucosyltransferases B, C and D (GtfB, GtfC and GtfD), either in solution (GtfB and GtfC) or when adsorbed to hydroxyapatite (GtfC and GtfD) at pH 6.5. …This s …754Cite
Fahey JW, Haristoy X, Dolan PM, Kensler TW, Scholtus I, Stephenson KK, Talalay P, Lozniewski A.Proc Natl Acad Sci U S A. 2002 May 28;99(11):7610-5. doi: 10.1073/pnas.112203099.PMID: 12032331 Free PMC article.
Eradication of this organism is an important medical goal that is complicated by the development of resistance to conventional antimicrobial agents and by the persistence of a low level reservoir of H. pylori within gastric epithelial cells. …755Cite
Structural features of interferon-gamma aggregation revealed by hydrogen exchange.
Tobler SA, Fernandez EJ.Protein Sci. 2002 Jun;11(6):1340-52. doi: 10.1110/ps.3770102.PMID: 12021433 Free PMC article.
Using hydrogen-deuterium exchange (HX) and electrospray ionization mass spectrometry, we have investigated the stability and structural changes of recombinant human interferon-gamma (IFN-gamma) during aggregation induced by guanidine hydrochloride (GdnHCl) and potassium thiocy …756Cite
Romagnoli C, Mares D, Bruni A, Andreotti E, Manfrini M, Vicentini CB.Mycopathologia. 2002;153(3):129-32. doi: 10.1023/a:1014593416665.PMID: 11998873
The data showed that the imidazo-pyrazole and pyrazolo-thiazoles were not particularly effective, while the two pyrazole-thiocyanates proved highly active on both fungi. The most active 5-amino-3-methyl-1-phenylpyrazolo-4-thiocyanate was chosen to perform SEM and TE …757Cite
Direct measurement of the viscoelasticity of adsorbed protein layers using atomic force microscopy.
Nemes C, Rozlosnik N, Ramsden JJ.Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1999 Aug;60(2 Pt A):R1166-9. doi: 10.1103/physreve.60.r1166.PMID: 11969944
Thick layers of the protein lysozyme have been deposited on mica, and their force-distance hysteresis measured using atomic force microscopy in the presence of different salts. Sodium thiocyanate, which is known to lower the melting temperature of proteins and increase the …758Cite
Tenovuo J.Oral Dis. 2002 Jan;8(1):23-9. doi: 10.1034/j.1601-0825.2002.1o781.x.PMID: 11936452 Review.
Innate human salivary defence proteins, lysozyme, lactoferrin and peroxidase, are known to exert a wide antimicrobial activity against a number of bacterial, viral and fungal pathogens in vitro. Therefore, these proteins, alone or in combinations, have been incorporated as …759Cite
Hofer T, Möller L.Chem Res Toxicol. 2002 Mar;15(3):426-32. doi: 10.1021/tx015573j.PMID: 11896691
A cold (0 degrees C) high salt GTC (4 M guanidine thiocyanate) nonphenol DNA extraction method was developed where DNA is quickly isolated. …760Cite
Cornejo LS, López de Blanc S, Femopase F, Azcurra A, Calamari S, Battellino LJ, Dorronsoro de Cattoni ST.Acta Odontol Latinoam. 1998;11(1):15-25.PMID: 11885450 Clinical Trial.761Cite
Shin K, Yamauchi K, Teraguchi S, Hayasawa H, Imoto I.J Med Microbiol. 2002 Mar;51(3):231-237. doi: 10.1099/0022-1317-51-3-231.PMID: 11871618
The susceptibility of Helicobacter pylori to the antimicrobial system involving lactoperoxidase, hydrogen peroxide and thiocyanate was investigated. …762Cite
Rapid extraction of DNA from diverse soils by guanidine thiocyanate method.
Agarwal A, Kumar C, Goel R.Indian J Exp Biol. 2001 Sep;39(9):906-10.PMID: 11831374
In the present study, we describe a protocol of DNA extraction from diverse soils using a combination of heat, enzyme (lysozyme) and guanidine thiocyanate. The efficacy of the procedure was evaluated in terms of yield, purity and duration of extraction. …763Cite
The unfolding mechanism and the disulfide structures of denatured lysozyme.
Chang JY, Li L.FEBS Lett. 2002 Jan 30;511(1-3):73-8. doi: 10.1016/s0014-5793(01)03284-7.PMID: 11821052 Free article.
Under denaturing conditions (urea, guanidinium hydrochloride (GdmCl), guanidinium thiocyanate (GdmSCN), or elevated temperature) and in the presence of thiol initiator, lysozyme denatures by shuffling its four native disulfide bonds and converts to a mixture of fully oxidi …764Cite
Formation of trithiocyanate in the oxidation of aqueous thiocyanate.
Barnett JJ, Stanbury DM.Inorg Chem. 2002 Jan 28;41(2):164-6. doi: 10.1021/ic015597d.PMID: 11800603765Cite
Suffys P, Vanderborght PR, Santos PB, Correa LA, Bravin Y, Kritski AL.Mem Inst Oswaldo Cruz. 2001 Nov;96(8):1137-9. doi: 10.1590/s0074-02762001000800019.PMID: 11784936 Free article.766Cite
Li XM, Novotná J, Vohradský J, Weiser J.Appl Microbiol Biotechnol. 2001 Dec;57(5-6):717-24. doi: 10.1007/s002530100807.PMID: 11778884
Expression of these prominent proteins was not observed in the non-producing mutant; moreover, they were overexpressed in cultures grown in the presence of benzyl thiocyanate, a specific stimulator of CTC biosynthesis used in industrial fermentations. …767Cite
Rasool NB, Monroe SS, Glass RI.J Virol Methods. 2002 Feb;100(1-2):1-16. doi: 10.1016/s0166-0934(01)00379-2.PMID: 11742648
Protocol (A), employed specimen lysis with guanidinium thiocyanate, extraction with phenol-chloroform-isoamyl alcohol and nucleic acid purification by size-fractionated silica particles. Protocol (B), utilised specimen lysis with guanidinium thiocyanate and nucleic …768Cite
Gönenç B, Sarimehmetoğlu HO.Dtsch Tierarztl Wochenschr. 2001 Oct;108(10):434-6.PMID: 11721592 Clinical Trial.769Cite
Courtenay ES, Capp MW, Record MT Jr.Protein Sci. 2001 Dec;10(12):2485-97. doi: 10.1110/ps.ps.20801.PMID: 11714916 Free PMC article.770Cite
PVC matrix membrane sensor for potentiometric determination of cetylpyridinium chloride.
Mostafa GA.Anal Sci. 2001 Sep;17(9):1043-7. doi: 10.2116/analsci.17.1043.PMID: 11708056 Free article.
A novel cetylpyridinium chloride-selective membrane sensor consisting of cetylpyridinium-ferric thiocyanate ion pairs dispersed in a PVC matrix placticized with dioctylphthalate is described. …771Cite
Capon RJ, Skene C, Liu EH, Lacey E, Gill JH, Heiland K, Friedel T.J Org Chem. 2001 Nov 16;66(23):7765-9. doi: 10.1021/jo0106750.PMID: 11701034772Cite
Synthesis of plagiochiline N from santonin.
Blay G, Cardona L, García B, Lahoz L, Pedro JR.J Org Chem. 2001 Nov 16;66(23):7700-5. doi: 10.1021/jo010567d.PMID: 11701024773Cite
Tew DJ, Bottomley SP.J Mol Biol. 2001 Nov 9;313(5):1161-9. doi: 10.1006/jmbi.2001.5104.PMID: 11700071774Cite
Denk MK, Gupta S, Brownie J, Tajammul S, Lough AJ.Chemistry. 2001 Oct 15;7(20):4477-86. doi: 10.1002/1521-3765(20011015)7:20<4477::aid-chem4477>3.0.co;2-i.PMID: 11695682
The reaction constitutes a new, solvent-free method for the synthesis of thioureas that eliminates the toxic and highly flammable CS2. For R = tBu, the ionic carbenium thiocyanates [LCH]+ SCN- dominate the product spectrum and the respective thioureas are obtained in low y …775Cite
Polyketide biosynthesis: a millennium review.
Staunton J, Weissman KJ.Nat Prod Rep. 2001 Aug;18(4):380-416. doi: 10.1039/a909079g.PMID: 11548049 Review. No abstract available.776Cite
Analysis time and lactation stage influence on lactoperoxidase system components in dairy ewe milk.
Althaus RL, Molina MP, Rodríguez M, Fernández N.J Dairy Sci. 2001 Aug;84(8):1829-35. doi: 10.3168/jds.S0022-0302(01)74622-X.PMID: 11518307 Free article.
The thiocyanate and hydrogen peroxide levels at different lactation stages seemed to be insufficient to activate the lactoperoxidase system. Nevertheless, this could be achieved by adding 5 mg/L of thiocyanate and 8 mg/L of hydrogen peroxide at any time during lacta …777Cite
A transient kinetic study on the reactivity of recombinant unprocessed monomeric myeloperoxidase.
Furtmüller PG, Jantschko W, Regelsberger G, Jakopitsch C, Moguilevsky N, Obinger C.FEBS Lett. 2001 Aug 17;503(2-3):147-50. doi: 10.1016/s0014-5793(01)02725-9.PMID: 11513872 Free article.
Firstly, hydrogen peroxide mediated both oxidation of ferric recMPO to compound I (1.9 x 10(7) M(-1) s(-1), pH 7 and 15 degrees C) and reduction of compound I to compound II (3.0 x 10(4) M(-1) s(-1), pH 7 and 15 degrees C). With chloride, bromide, iodide and thiocyanate co …778Cite
Bernabéu JA, Camacho MA, Gil-Alegre ME, Torres-Suárez AI.J Agric Food Chem. 2001 Aug;49(8):3709-12. doi: 10.1021/jf010169b.PMID: 11513652
In this paper, a stability study of a medicated premix and medicated farm feed containing erythromycin thiocyanate was planned. No drug degradation was detected during the medicated farm feed processing. …Because after 2 years of storage at 25 degrees C and 60% relative …779Cite
Chiang Y, Kresge AJ, Zhu Y.J Am Chem Soc. 2001 Aug 22;123(33):8089-94. doi: 10.1021/ja010826g.PMID: 11506565
Decay of the quinone methide is also accelerated by acetic acid buffers through both acid- and base-catalyzed pathways, and quantitative analysis of the reaction products formed in these solutions shows that this acceleration is caused by nucleophilic reactions of acetate ion rat …780Cite
Substrates and products of eosinophil peroxidase.
van Dalen CJ, Kettle AJ.Biochem J. 2001 Aug 15;358(Pt 1):233-9. doi: 10.1042/0264-6021:3580233.PMID: 11485572 Free PMC article.
On the basis of these values thiocyanate is preferred 2.8-fold over bromide as a substrate for eosinophil peroxidase. …We conclude that at plasma concentrations of bromide (20-120 microM) and thiocyanate (20-100 microM), hypobromous acid and oxidation products of …781Cite
Moczygemba C, Guidry J, Jones KL, Gomes CM, Teixeira M, Wittung-Stafshede P.Protein Sci. 2001 Aug;10(8):1539-48. doi: 10.1110/ps.49401.PMID: 11468351 Free PMC article.
Only by the use of the stronger denaturant guanidine thiocyanate (GuSCN) is unfolding of A. ambivalens ferredoxin at pH 7 (20 degrees C) observed ([GuSCN](1/2) = 3.1 M; DeltaG(U)[H(2)O] = 79 +/- 8 kJ/mole). …782Cite
An efficient method for extraction of RNA from rice leaves at different ages using benzyl chloride.
Suzuki Y, Makino A, Mae T.J Exp Bot. 2001 Jul;52(360):1575-9. doi: 10.1093/jexbot/52.360.1575.PMID: 11457918
With a conventional method of RNA extraction using an acid guanidinium thiocyanate-water-saturated phenol-chloroform mixture, extraction efficiency of extractable RNA to total RNA (extractable RNA+ residual RNA) in rice leaves at various ages was 54-69%. …783Cite
Antimicrobial effect of acidified nitrite on periodontal bacteria.
Allaker RP, Silva Mendez LS, Hardie JM, Benjamin N.Oral Microbiol Immunol. 2001 Aug;16(4):253-6. doi: 10.1034/j.1399-302x.2001.160410.x.PMID: 11442852
The antimicrobial agent nitric oxide (NO) is formed in the mouth and its concentration is directly related to salivary nitrite, which in turn is related to dietary nitrate intake. …At acidity levels below pH 5.0, low concentrations of nitrite (0.2 mM) caused effective co …784Cite
Schöne F, Leiterer M, Hartung H, Jahreis G, Tischendorf F.Br J Nutr. 2001 Jun;85(6):659-70. doi: 10.1079/bjn2001326.PMID: 11430770
The presence of rapeseed and rapeseed press cake were indicated by a thiocyanate concentration increase, mainly in sow serum. The diets with glucosinolates decreased the milk and piglet serum I concentration. …785Cite
Isolation of total RNA from pollens.
Bijli KM, Singh BP, Sridhara S, Arora N.Prep Biochem Biotechnol. 2001 May;31(2):155-62. doi: 10.1081/PB-100103381.PMID: 11426703786Cite
Carr AC, Decker EA, Park Y, Frei B.Free Radic Biol Med. 2001 Jul 1;31(1):62-72. doi: 10.1016/s0891-5849(01)00552-4.PMID: 11425491
Interestingly, even at physiological concentrations of the two halides (100 mM Cl(-), 100 microM Br(-)), MPO utilized a portion of the Br(-) to oxidize apoB cysteine residues. MPO also utilized the pseudohalide thiocyanate to oxidize apoB cysteine residues. Our data show t …787Cite
Structural effects of monovalent anions on polymorphic lysozyme crystals.
Vaney MC, Broutin I, Retailleau P, Douangamath A, Lafont S, Hamiaux C, Prangé T, Ducruix A, Riès-Kautt M.Acta Crystallogr D Biol Crystallogr. 2001 Jul;57(Pt 7):929-40. doi: 10.1107/s0907444901004504. Epub 2001 Jun 21.PMID: 11418760
These new structures are compared with previously published structures in order to draw a mapping of the surface of different lysozymes interacting with monovalent anions, such as nitrate, chloride, iodide, bromide and thiocyanate. An analysis of the structural sites of th …788Cite
Glutathione transport system in NIH3t3 fibroblasts.
Favilli F, Catarzi S, Iantomasi T, Vincenzini MT.Mol Cell Biol Res Commun. 2000 Oct;4(4):212-8. doi: 10.1006/mcbr.2001.0280.PMID: 11409914789Cite
Inhibitory effect of lactoperoxidase-generated hypothiocyanite upon black pigmented anaerobe growth.
Fadel M, Courtois P.Int J Mol Med. 2001 Jul;8(1):59-62.PMID: 11408950
This study aimed to evaluate the in vitro effect of lactoperoxidase with or without its substrates (hydrogen peroxide, thiocyanate) on the growth of 4 different black pigmented anaerobe (BPA) strains associated with the development and progress of periodontal diseases: Por …790Cite
Dietary supplies of iodine and thiocyanate in the etiology of endemic goiter in Tripura.
Chandra AK, Ray I.Indian J Pediatr. 2001 May;68(5):399-404. doi: 10.1007/BF02723011.PMID: 11407152
The clinical variable of the study was goiter and the biochemical variables were urinary iodine and thiocyanate. Random sampling methodology was followed for selecting the study areas in the State. …This study ensures that the existing goiter prevalence in the region cou …791Cite
Benzyl isothiocyanate is the chief or sole anthelmintic in papaya seed extracts.
Kermanshai R, McCarry BE, Rosenfeld J, Summers PS, Weretilnyk EA, Sorger GJ.Phytochemistry. 2001 Jun;57(3):427-35. doi: 10.1016/s0031-9422(01)00077-2.PMID: 11393524
A 10 h incubation of crude seed extracts at room temperature led to a decrease in anthelmintic activity and fractionated samples showed a lower benzyl isothiocyanate content relative to non-incubated controls. Benzyl thiocyanate, benzyl cyanide, and benzonitrile were not d …792Cite
Ribonuclease Rs from Rhizopus stolonifer: lowering of optimum temperature in the presence of urea.
Deshpande RA, Kumar AR, Khan MI, Shankar V.Biochim Biophys Acta. 2001 Feb 9;1545(1-2):13-9. doi: 10.1016/s0167-4838(00)00256-9.PMID: 11342027793Cite
Endemic goiter, thiocyanate overload, and selenium status in school-age children.
Erdoğan MF, Erdoğan G, Sav H, Güllü S, Kamel N.Biol Trace Elem Res. 2001 Feb;79(2):121-30. doi: 10.1385/BTER:79:2:121.PMID: 11330518
The current study attempted to evaluate selenium (Se) status, thiocyanate (SCN-) overload, and their possible contribution to the goiter endemics and thyroid hormone profile observed in these cities. …794Cite
Xu Y, Lu J, Li DQ.Prep Biochem Biotechnol. 2001 Feb;31(1):23-31. doi: 10.1081/PB-100103369.PMID: 11321161
The effect of potassium thiocyanate on the partitioning of lysozyme and BSA in polyethylene glycol 2000/ammonium sulfate aqueous two-phase system has been investigated. As a result of the addition of potassium thiocyanate to the PEG/ammonium sulfate system, the PEG/ …795Cite
Effect of lactoperoxidase system on glucosyltransferase D of Streptococcus mutans.
Yu X, Loimaranta V, Lenander-Lumikari M, Wunder D, Bowen WH, Tenuvuo J.Chin J Dent Res. 2000 Aug;3(2):61-4.PMID: 11314522
However, if LP was combined with its substrates, SCN and/or a high concentration of H2O2, it enhanced the activity of GtfD. CONCLUSION: Peroxidase-generated antimicrobial agent HOSCN/OSCN is not inhibitory against GtfD, whereas low concentrations of the LP-enzyme inhibit G …796Cite
Xu J, Xu X, Verstraete W.J Appl Microbiol. 2001 Apr;90(4):523-9. doi: 10.1046/j.1365-2672.2001.01278.x.PMID: 11309062
The bactericidal effects were enhanced by thiocyanate but not by L-ascorbic acid and iodide. L-Ascorbic acid and thiocyanate, but not iodide, enhanced the decomposition of acidified nitrite in nutrient broth. …SIGNIFICANCE AND IMPACT OF THE STUDY: The potential ro …797Cite
Shin K, Hayasawa H, Lönnerdal B.J Appl Microbiol. 2001 Apr;90(4):489-93. doi: 10.1046/j.1365-2672.2001.01268.x.PMID: 11309058
AIMS: The lactoperoxidase-hydrogen peroxide-thiocyanate antimicrobial system (LPAS) is known to inhibit bacterial respiration. In the present study, several respiratory enzymes of Escherichia coli were compared in terms of their susceptibility to the LPAS. …798Cite
Tobler SA, Sherman NE, Fernandez EJ.Biotechnol Bioeng. 2000-2001;71(3):194-207. doi: 10.1002/1097-0290(2000)71:3<194::aid-bit1009>3.0.co;2-q.PMID: 11291029
Precipitation with 1.0 M thiocyanate resulted in faster rates of unfolding and larger amounts of the insoluble precipitate. …Bimodal mass distributions in the ESI-MS spectra for the thiocyanate precipitates indicate two states for lysozyme in this system, a native …799Cite
Effects of SCN-/H2O2 combinations in dentifrices on plaque and gingivitis.
Rosin M, Kocher T, Kramer A.J Clin Periodontol. 2001 Mar;28(3):270-6. doi: 10.1034/j.1600-051x.2001.028003270.x.PMID: 11284542 Clinical Trial.
OBJECTIVES: A 10-week, double-blind, placebo-controlled clinical study on 140 male subjects was conducted to determine the effect on plaque and gingivitis of 5 dentifrices containing various thiocyanate (SCN-)/hydrogen peroxide (H2O2) combinations. MATERIALS AND METHODS: T …800Cite
Mohamed GG.J Pharm Biomed Anal. 2001 Feb;24(4):561-7. doi: 10.1016/s0731-7085(00)00463-5.PMID: 11272312
The method involves the formation of ion-pairs between these drugs under investigation and inorganic complex of Mo (V) thiocyanate followed by its extraction with methylene chloride. The optimum conditions for the ion-pairs formation are established. …
Abdul Kamal Nazer M, Shabeer TK, Riyazuddin P.Chem Pharm Bull (Tokyo). 2001 Mar;49(3):278-81. doi: 10.1248/cpb.49.278.PMID: 11253916 Free article.802Cite
Loiseau PM, Dreyfuss G, Doadrio L, Parrondo E, Craciunescu DG.J Chemother. 2001 Feb;13(1):59-65. doi: 10.1179/joc.2001.13.1.59.PMID: 11233802
Cis-platinum-pentamidine bromide, cis-platinum-pentamidine seleniocyanate, and cis-platinum-pentamidine thiocyanate were distributed in the deep compartment according to a monocompartmental model. …803Cite
Ihalin R, Loimaranta V, Lenander-Lumikari M, Tenovuo J.J Med Microbiol. 2001 Jan;50(1):42-48. doi: 10.1099/0022-1317-50-1-42.PMID: 11192504
In the present study, the effects of iodide, chloride and thiocyanate in combinations with lactoperoxidase (LP) and myeloperoxidase (MP) on the viability of Porphyromonas gingivalis, Fusobacterium nucleatum, Streptococcus mutans and S. rattus were analysed. …The effect w …804Cite
Salt and cosolvent effects on ionic drug loading into microspheres using an O/W method.
Al-Maaieh A, Flanagan DR.J Control Release. 2001 Jan 29;70(1-2):169-81. doi: 10.1016/s0168-3659(00)00347-3.PMID: 11166417
Quinidine sulfate solubility was depressed by either a common ion effect (Na(2)SO(4)) or by formation of new, less soluble drug salts (e.g., bromide, perchlorate, thiocyanate) for which solubility products (K(sp)) were estimated. Inorganic salts depress DCM aqueous solubil …805Cite
Chang JY, Li L.J Biol Chem. 2001 Mar 30;276(13):9705-12. doi: 10.1074/jbc.M010700200. Epub 2000 Dec 15.PMID: 11118458 Free article.
Under denaturing conditions (urea, guanidine hydrochloride, guanidine thiocyanate, organic solvent or elevated temperature) and in the presence of thiol initiator, alpha-LA denatures by shuffling its four native disulfide bonds and converts to a mixture of fully oxidized s …806Cite
Cellular effects of leishmanial tubulin inhibitors on L. donovani.
Havens CG, Bryant N, Asher L, Lamoreaux L, Perfetto S, Brendle JJ, Werbovetz KA.Mol Biochem Parasitol. 2000 Oct;110(2):223-36. doi: 10.1016/s0166-6851(00)00272-3.PMID: 11071278
To aid our investigation of tubulin as an antileishmanial drug target, the effects of the mammalian antimicrotubule agents ansamitocin P3, taxol, and hemiasterlin on Leishmania donovani promastigotes were described. …These studies validate tubulin as a suitable antileish …807Cite
Li Q, Wei W, Liu Q.Analyst. 2000 Oct;125(10):1885-8. doi: 10.1039/b004497k.PMID: 11070558
A new method for the indirect determination of thiocyanate with ammonium sulfate and ethanol by extraction-flotation of copper in the presence of ascorbic acid is described. …Using 1.0 ml of 1 x 10(-3) M ascorbic acid solution, 50 micrograms of Cu(II), 3.5 g of (NH4)2SO4 …808Cite
Yildirim A, Mavi A, Oktay M, Kara AA, Algur OF, Bilaloglu V.J Agric Food Chem. 2000 Oct;48(10):5030-4. doi: 10.1021/jf000590k.PMID: 11052773
The antioxidant activity of the water extract of Tilia argentea Desf ex DC was determined by the thiocyanate method. The antioxidant activity of the water extract increased with the increasing amount of lyophilized extract (50-400 microg) added into the linoleic acid emuls …809Cite
Arlandson M, Decker T, Roongta VA, Bonilla L, Mayo KH, MacPherson JC, Hazen SL, Slungaard A.J Biol Chem. 2001 Jan 5;276(1):215-24. doi: 10.1074/jbc.M004881200.PMID: 11013238 Free article.
Although the pseudohalide thiocyanate (SCN(-)) is the preferred substrate for eosinophil peroxidase (EPO) in fluids of physiologic halide composition, the product(s) of this reaction have not been directly identified, and mechanisms underlying their cytotoxic potential are …810Cite
García-Graells C, Valckx C, Michiels CW.Appl Environ Microbiol. 2000 Oct;66(10):4173-9. doi: 10.1128/AEM.66.10.4173-4179.2000.PMID: 11010856 Free PMC article.
We have studied inactivation of four strains each of Escherichia coli and Listeria innocua in milk by the combined use of high hydrostatic pressure and the lactoperoxidase-thiocyanate-hydrogen peroxide system as a potential mild food preservation method. The lactoperoxidas …811Cite
Gadad AK, Mahajanshetti CS, Nimbalkar S, Raichurkar A.Eur J Med Chem. 2000 Sep;35(9):853-7. doi: 10.1016/s0223-5234(00)00166-5.PMID: 11006486
6-Arylimidazo[2,1-b]-1,3,4-thiadiazole-2-sulfonamides 3 on Vilsmeier-Haak reaction produced 5-formyl-6-arylimidazo[2,1-b]-1,3, 4-thiadiazole-2-[N-(dimethylaminomethino)]sulfonamides 4, while 3 on treatment with potassium thiocyanate in the presence of bromine in acetic aci …812Cite
Effect of prolactin on sodium iodide symporter expression in mouse mammary gland explants.
Rillema JA, Yu TX, Jhiang SM.Am J Physiol Endocrinol Metab. 2000 Oct;279(4):E769-72. doi: 10.1152/ajpendo.2000.279.4.E769.PMID: 11001757 Free article.
The lowest PRL concentration that elicited a significant response was 1 ng/ml, and a maximum effect was elicited with PRL concentrations >100 ng/ml. Actinomycin D, cycloheximide, and thiocyanate abolished the PRL effect on NIS accumulation, whereas perchlorate was witho …813Cite
Amin AS, Aly HM.Int J Pharm. 2000 Sep 15;205(1-2):35-41. doi: 10.1016/s0378-5173(00)00467-1.PMID: 11000540814Cite
Bosch EH, van Doorne H, de Vries S.J Appl Microbiol. 2000 Aug;89(2):215-24. doi: 10.1046/j.1365-2672.2000.01098.x.PMID: 10971753
The effect of adding iodide to the LP system, the chemical stability and the change in antimicrobial effectiveness during storage was studied. Addition of iodide with thiocyanate increased the fungicidal and bactericidal effect against Candida albicans, Escherichia …815Cite
Ateş O, Altintaş H, Otük G.Arzneimittelforschung. 2000 Jun;50(6):569-75. doi: 10.1055/s-0031-1300251.PMID: 10918953
Furthermore, I-IV were refluxed with ammonium thiocyanate to give 2-[(4-carbethoxymethylthiazol-2-yl)imino]-4-thiazolidinones (V-VIII). …The structures of synthesized compounds were confirmed by elemental analyses, hydrolysis, UV, IR, 1H-NMR and EI mass spectral data. Th …816Cite
The effects of glycopyrrolate on oral mucous host defenses in healthy volunteers.
Lähteenmäki MT, Salo MS, Tenovuo JO, Helminen AV, Vilja PJ, Huupponen RK.Anesth Analg. 2000 Aug;91(2):467-72. doi: 10.1097/00000539-200008000-00045.PMID: 10910870 Clinical Trial.
Salivary flow rates and the concentrations/activities of total protein, amylase, and nonimmunologic (lysozyme, lactoferrin, myeloperoxidase, total salivary peroxidase, and thiocyanate) and immunologic (total immunoglobulin A, immunoglobulin G, and immunoglobulin M) mucous …817Cite
Suryaprakash P, Prakash V.Nahrung. 2000 Jun;44(3):178-83. doi: 10.1002/1521-3803(20000501)44:3<178::AID-FOOD178>3.0.CO;2-D.PMID: 10907239
Helianthinin (11S), a multisubunit protein from Sunflower Seeds (Helianthus annuus L.) dissociates to its monomer (2S) through a trimeric (7S) intermediate as a function of guanidine hydrochloride (GuHCl) and guanidine thiocyanate (GuHSCN) concentration. Measurements of vi …818Cite
Thiocyanate mediated antifungal and antibacterial property of goat milk lactoperoxidase.
Benoy MJ, Essy AK, Sreekumar B, Haridas M.Life Sci. 2000;66(25):2433-9. doi: 10.1016/s0024-3205(00)80003-x.PMID: 10894086
The purified protein was found to have high antifungal and antibacterial activity in a thiocyanate-H2O2 medium. The results are relevant enough to suggest the exploitation of LP-thiocyanate-H2O2 system as an effective agent against many of the disease causing organi …819Cite
Privat N, Sazdovitch V, Seilhean D, LaPlanche JL, Hauw JJ.Microsc Res Tech. 2000 Jul 1;50(1):26-31. doi: 10.1002/1097-0029(20000701)50:1<26::AID-JEMT5>3.0.CO;2-S.PMID: 10871545
In addition, a technique useful after long formalin fixation is reported: enzymatic digestion with proteinase K (24 degrees C, 1/100 for 8 minutes) was employed in addition to the usual autoclaving (121 degrees C for 10 minutes) followed by formic acid (99% for 5 minutes) and 4M …820Cite
Determination of hydroperoxides in liposomes by the modified IDF and the modified tiron methods.
Gabriëls M, Cirunay J, Alafandy M, Brisaert M, de Taevernier M, Camu F, Plaizier-Vercammen J.J AOAC Int. 2000 May-Jun;83(3):589-96.PMID: 10868581
Interferences of alpha-tocoferol and egg-phosphatidylcholine (EPC) required a solid-phase extraction before the analysis to eliminate alpha-tocoferol and a fluid-fluid extraction based on the solvent triangle of Bligh and Dyer to separate EPC. The developed color, using thiocy …821Cite
The lactoperoxidase system functions in bacterial clearance of airways.
Gerson C, Sabater J, Scuri M, Torbati A, Coffey R, Abraham JW, Lauredo I, Forteza R, Wanner A, Salathe M, Abraham WM, Conner GE.Am J Respir Cell Mol Biol. 2000 Jun;22(6):665-71. doi: 10.1165/ajrcmb.22.6.3980.PMID: 10837362
Airway mucus is a complex mixture of secretory products that provides a multifaceted defense against pulmonary infection. Mucus contains antimicrobial peptides (e.g., defensins) and enzymes (e.g., lysozyme) although the contribution of these to airway sterility has not bee …822Cite
Gallez F, Fadel M, Scruel O, Cantraine F, Courtois P.Cell Biochem Funct. 2000 Jun;18(2):103-8. doi: 10.1002/(SICI)1099-0844(200006)18:2<103::AID-CBF860>3.0.CO;2-N.PMID: 10814968823Cite
The structure of denatured bovine pancreatic trypsin inhibitor (BPTI).
Chang J, Ballatore A.FEBS Lett. 2000 May 12;473(2):183-7. doi: 10.1016/s0014-5793(00)01515-5.PMID: 10812071 Free article.
BPTI is an exceedingly stable molecule and can be effectively denatured only by guanidine thiocyanate (GdmSCN) at concentrations higher than 3-4 M. The denatured BPTI consists of at least eight fractions of scrambled isomers. …824Cite
de Vries TJ, Fourkour A, Punt CJ, Ruiter DJ, van Muijen GN.Melanoma Res. 2000 Apr;10(2):119-26.PMID: 10803712825Cite
Szajnman SH, Yan W, Bailey BN, Docampo R, Elhalem E, Rodriguez JB.J Med Chem. 2000 May 4;43(9):1826-40. doi: 10.1021/jm9905007.PMID: 10794699
As a part of our project directed at the search of new chemotherapeutic agents against American trypanosomiasis (Chagas’ disease), several drugs possessing the 4-phenoxyphenoxy skeleton and other closely related structures employing the thiocyanate moiety as polar e …826Cite
Jacobs MV, Zielinski D, Meijer CJ, Pol RP, Voorhorst FJ, de Schipper FA, Runsink AP, Snijders PJ, Walboomers JM.Br J Cancer. 2000 Apr;82(8):1421-6. doi: 10.1054/bjoc.1999.1128.PMID: 10780521 Free PMC article.
Two of the methods were based on proteinase K treatment and two based on treatment with guanidinium thiocyanate (GTC). The quality of the DNA as measured by PCR assays amplifying different sizes of the beta-globin gene appeared to be superior for the GTC-based assays. …827Cite
Langouët S, Furge LL, Kerriguy N, Nakamura K, Guillouzo A, Guengerich FP.Chem Res Toxicol. 2000 Apr;13(4):245-52. doi: 10.1021/tx990189w.PMID: 10775323
Recent studies have demonstrated that two chemoprotective agents, oltipraz (OPZ), a synthetic derivative of the natural compound 1, 2-dithiole-3-thione (D3T), and sulforaphane (SF), an isothiocyanate, are not only inducers of glutathione S-transferases but also inhibitors …828Cite
Khalil S, El-Rabiehi MM.J Pharm Biomed Anal. 2000 Feb;22(1):7-12. doi: 10.1016/s0731-7085(99)00240-x.PMID: 10727118
The method is based on precipitation of the ion associates formed from the reaction of (1), (2) or (3) with manganese thiocyanate and/or potassium ferricyanide. The solubility of the solid complexes at the optimum conditions of pH and ionic strength values have been studie …829Cite
Khalil S, Borham N.J Pharm Biomed Anal. 2000 Mar;22(2):235-40. doi: 10.1016/s0731-7085(99)00269-1.PMID: 10719905830Cite
Determinants of thyroid volume in healthy French adults participating in the SU.VI.MAX cohort.
Barrère X, Valeix P, Preziosi P, Bensimon M, Pelletier B, Galan P, Hercberg S.Clin Endocrinol (Oxf). 2000 Mar;52(3):273-8. doi: 10.1046/j.1365-2265.2000.00939.x.PMID: 10718824
Serum TSH and free thyroxine (fT4) were measured in duplicate. Urinary iodine and urinary thiocyanate were assayed in random morning urine samples. RESULTS: For both sexes, thyroid volume (ml) was positively correlated with weight, height, body mass index and body surface …831Cite
Microbiological bioassay of erythromycin thiocyanate: optimisation and validation.
Bernabéu JA, Camacho MA, Gil-Alegre ME, Ruz V, Torres-Suárez AI.J Pharm Biomed Anal. 1999 Nov;21(2):347-53. doi: 10.1016/s0731-7085(99)00143-0.PMID: 10703990
The validation of an analytical method for the quantitative determination of erythromycin thiocyanate formulated in an antibiotic preparation for veterinary use was carried out. This method is based on the microbiological method described in the European Pharmacopoeia to a …832Cite
Khalil S.J Pharm Biomed Anal. 1999 Dec;21(4):697-702. doi: 10.1016/s0731-7085(99)00130-2.PMID: 10701933833Cite
Alm EW, Stahl DA.J Microbiol Methods. 2000 Apr;40(2):153-62. doi: 10.1016/s0167-7012(00)00120-2.PMID: 10699671
Most notably, the order of addition and the buffer to sample volume ratio profoundly influenced the efficiency of nucleic acid recovery from sediment material when utilizing a guanidine thiocyanate-beta-mercaptoethaol extraction buffer. Addition of one sample volume to fiv …834Cite
Elnour A, Hambraeus L, Eltom M, Dramaix M, Bourdoux P.Am J Clin Nutr. 2000 Jan;71(1):59-66. doi: 10.1093/ajcn/71.1.59.PMID: 10617947
Although serum thyroxine and triiodothyronine concentrations were within reference ranges, the median thyrotropin concentration was 3.78 mIU/L and 44% of the children had thyrotropin concentrations above normal. The mean urinary thiocyanate concentration was high (259 +/- …835Cite
The lack of transplacental movement of the cyanide antidote thiosulfate in gravid ewes.
Graeme KA, Curry SC, Bikin DS, Lo Vecchio FA, Brandon TA.Anesth Analg. 1999 Dec;89(6):1448-52. doi: 10.1097/00000539-199912000-00023.PMID: 10589625
Fetal cyanide may cross down a concentration gradient from fetal to maternal circulation, to be transulfurated to thiocyanate in maternal tissues. IMPLICATIONS: We evaluated the mechanism of action of sodium thiosulfide (STS) in sodium nitroprusside-induced cyanide toxicit …836Cite
Assessment of goiter in an area of endemic iodine deficiency.
Smyth PP, Darke C, Parkes AB, Smith DF, John R, Hetherton AM, Lazarus JH.Thyroid. 1999 Sep;9(9):895-901. doi: 10.1089/thy.1999.9.895.PMID: 10524568
Thyroid enlargement was not associated with ethnic origin, thiocyanate ingestion, HLA DR/DQ phenotype frequency, or thyroid growth-stimulating immunoglobulin (TGI) positivity. …837Cite
Meyer RK, Oesch B, Fatzer R, Zurbriggen A, Vandevelde M.J Virol. 1999 Nov;73(11):9386-92. doi: 10.1128/JVI.73.11.9386-9392.1999.PMID: 10516047 Free PMC article.
However, following treatment of the tissue with heat and guanidine thiocyanate (Gh treatment), the ELISA discriminated BSE-specific PrP(Sc) from PrP(C) in bovine brain homogenates. …838Cite
Khaspekov L, Friberg H, Halestrap A, Viktorov I, Wieloch T.Eur J Neurosci. 1999 Sep;11(9):3194-8. doi: 10.1046/j.1460-9568.1999.00743.x.PMID: 10510183
Both cyclosporin A and N-Me-Val-4-cyclosporin A markedly attenuated calcium-induced swelling of isolated mouse brain mitochondria by blocking the mitochondrial permeability transition. The potassium thiocyanate-stabilized binding of cyclophilin D to mouse brain mitochondri …839Cite
Zhang Q, Zhang Y.Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1997 Oct;19(5):384-8.PMID: 10453526 Chinese.
Total RNA was isolated with the single step method of acid guanidinium thiocyanate. After being digested by DNase I, the two RNA samples were differentially displayed with T12MA/T/C/G x 20 arbitrary primer pairs. …840Cite
Permeability transition pore closure promoted by quinine.
Catisti R, Vercesi AE.J Bioenerg Biomembr. 1999 Apr;31(2):153-7. doi: 10.1023/a:1005455912711.PMID: 10449242841Cite
Synthesis, reactions and biological activity of some new thieno[2,3-f]-1,3-benzodioxoles.
Bakhite EA, Radwan SM.Pharmazie. 1999 Jul;54(7):491-8.PMID: 10445243
Compound 2 was also reacted with potassium thiocyanate, ethanol or sodium azide to afford the isothiocyanto compound 6, the ester 7 and the acid azide 9, respectively. …842Cite
Analysis of the extent of unfolding of denatured insulin-like growth factor.
Chang JY, Märki W, Lai PH.Protein Sci. 1999 Jul;8(7):1463-8. doi: 10.1110/ps.8.7.1463.PMID: 10422834 Free PMC article.843Cite
Gröne A, Fonfara S, Markus S, Baumgärtner W.Zentralbl Veterinarmed B. 1999 Jun;46(5):301-10. doi: 10.1111/j.1439-0450.1999.tb01235.x.PMID: 10416364
Three different methods of RNA isolation (standard guanidinium-thiocyanate method with and without application of RNA matrix, and boiling) were used and compared in regard to RT-PCR results. …These findings demonstrated that isolation of total RNA with guanidinium-thi …844Cite
Boussouel N, Mathieu F, Benoit V, Linder M, Revol-Junelles AM, Millière JB.J Appl Microbiol. 1999 Apr;86(4):642-52. doi: 10.1046/j.1365-2672.1999.00707.x.PMID: 10212409
Experimental designs using Response Surface Methodology (RSM) were used to determine effects and interactions of Nisin (0-200 i.u. ml-1), pH values (5.4-6.6), incubation time (0-36 h or 0-144 h) and the lactoperoxidase-thiocyanate-hydrogen peroxide system (LPS) on Listeria …845Cite
van der Linden RH, Frenken LG, de Geus B, Harmsen MM, Ruuls RC, Stok W, de Ron L, Wilson S, Davis P, Verrips CT.Biochim Biophys Acta. 1999 Apr 12;1431(1):37-46. doi: 10.1016/s0167-4838(99)00030-8.PMID: 10209277
Llama VHH antibody fragments are similar to mouse monoclonal antibodies with respect to antigen binding in the presence of ammonium thiocyanate and ethanol. The results show that relative to antigen specific mouse monoclonal antibodies, antigen specific llama VHH fragments …846Cite
Gutierrez-Correa J, Stoppani AO.Free Radic Res. 1999 Feb;30(2):105-17. doi: 10.1080/10715769900300111.PMID: 10193578
LADH inactivation was a function of the composition of the inactivating system and the incubation time. Chloride, iodide, bromide, and the thiocyanate anions were effective complements of the MPO/H2O2 system. NaOCl inactivated LADH, thus supporting hypochlorous acid (HOCl) …847Cite
Contribution of the lactoperoxidase system to the keeping quality of pasteurized milk.
Barrett NE, Grandison AS, Lewis MJ.J Dairy Res. 1999 Feb;66(1):73-80. doi: 10.1017/s0022029998003252.PMID: 10191475
The lactoperoxidase system is a naturally occurring antimicrobial system found in milk, with lactoperoxidase, thiocyanate and hydrogen peroxide as its components. …Higher levels of hypothiocyanite (the major antimicrobial agent produced by the lactoperoxida …848Cite
[Iodine deficiency and iodine prophylaxis experience in Sicily].
Regalbuto C, Salamone S, La Rosa GL, Calaciura F, Buscema M, Vigneri R.Ann Ist Super Sanita. 1998;34(3):429-36.PMID: 10052190 Italian.
In this area endemic goiter was associated to a variable degree of iodine deficiency and, in some places, also to an increased thiocyanate urine excretion. Our studies have demonstrated a strict relationship between iodine deficiency and congenital hypothyroidism (both per …849Cite
Boom R, Sol C, Beld M, Weel J, Goudsmit J, Wertheim-van Dillen P.J Clin Microbiol. 1999 Mar;37(3):615-9. doi: 10.1128/JCM.37.3.615-619.1999.PMID: 9986822 Free PMC article.850Cite
Identification of the cyclosporin-binding site in P-glycoprotein.
Demeule M, Laplante A, Murphy GF, Wenger RM, Béliveau R.Biochemistry. 1998 Dec 22;37(51):18110-8. doi: 10.1021/bi981992c.PMID: 9922180
This cyclosporin A binding site was further characterized with chemical agents (N-chlorosuccinimide, cyanogen bromide, and 2-nitro-5-thiocyanobenzoate). These three chemical agents established a proteolytic profile of P-glycoprotein for fragments photolabeled with c …851Cite
Reaction of myeloperoxidase compound I with chloride, bromide, iodide, and thiocyanate.
Furtmüller PG, Burner U, Obinger C.Biochemistry. 1998 Dec 22;37(51):17923-30. doi: 10.1021/bi9818772.PMID: 9922160
The enzyme uses hydrogen peroxide to oxidize chloride (Cl-), bromide (Br-), iodide (I-), and the pseudohalide thiocyanate (SCN-) to their respective hypohalous acids. This study for the first time presents transient kinetic measurements of the oxidation of these halides an …852Cite
Isolation of high-molecular-weight genomic DNA from intact biohazardous mammalian tissues.
Liska V, Ruprecht RM.Biotechniques. 1999 Jan;26(1):62-4, 66. doi: 10.2144/99261bm09.PMID: 9894593 Free article. No abstract available.853Cite
Heuvelink AE, Bleumink B, van den Biggelaar FL, Te Giffel MC, Beumer RR, de Boer E.J Food Prot. 1998 Dec;61(12):1597-601. doi: 10.4315/0362-028x-61.12.1597.PMID: 9874335 Free article.
Naturally occurring amounts of thiocyanate and hydrogen peroxide in the raw milk tested were not sufficient to activate the LPS. Although the LPS exhibited an antimicrobial activity against O157 VTEC in LPS-activated sterilized milk, O157 VTEC populations were not ( …854Cite
Loimaranta V, Tenovuo J, Korhonen H.Oral Microbiol Immunol. 1998 Dec;13(6):378-81. doi: 10.1111/j.1399-302x.1998.tb00695.x.PMID: 9872115855Cite
Antimicrobial function of human saliva–how important is it for oral health?
Tenovuo J.Acta Odontol Scand. 1998 Oct;56(5):250-6. doi: 10.1080/000163598428400.PMID: 9860091 Review.
Human saliva contains a number of physical physicochemical, and chemical agents that protect oral tissues against noxious compounds, in particular those produced by various microorganisms. …Increased knowledge of the molecular functions of various agents has made …856Cite
Ihalin R, Loimaranta V, Lenander-Lumikari M, Tenovuo J.J Periodontal Res. 1998 Oct;33(7):421-7. doi: 10.1111/j.1600-0765.1998.tb02338.x.PMID: 9842507
Both peroxidases produced end products with identical antibacterial activity with thiocyanate and iodide. The oxidation of iodide resulted in the highest antimicrobial efficiency followed by chloride and thiocyanate. …However, the chloride did not affect th …857Cite
Adak S, Bandyopadhyay U, Bandyopadhyay D, Banerjee RK.Biochemistry. 1998 Dec 1;37(48):16922-33. doi: 10.1021/bi980899l.PMID: 9836585858Cite
Yoshida A, Sasaki N, Mori A, Taniguchi S, Ueta Y, Hattori K, Tanaka Y, Igawa O, Tsuboi M, Sugawa H, Sato R, Hisatome I, Shigemasa C, Grollman EF, Kosugi S.Biochim Biophys Acta. 1998 Nov 11;1414(1-2):231-7. doi: 10.1016/s0005-2736(98)00169-2.PMID: 9804961 Free article.859Cite
Akin A, Wu CC, Lin TL.J Virol Methods. 1998 Oct;74(2):179-84. doi: 10.1016/s0166-0934(98)00082-2.PMID: 9779617860Cite
Délye C, Corio-Costet MF.J Virol Methods. 1998 Oct;74(2):149-53. doi: 10.1016/s0166-0934(98)00079-2.PMID: 9779614
Lyophilised fungal material is incubated in a commercial guanidium thiocyanate reagent. Proteins and cell debris are centrifuged by chloroform precipitation. …861Cite
Cleaning CJD-contaminated instruments.
Manuelidis L.Science. 1998 Sep 25;281(5385):1961. doi: 10.1126/science.281.5385.1961c.PMID: 9767039 No abstract available.862Cite
Diverse effects of mild and potent goitrogens on blood-brain barrier nutrient transport.
Raghunath M, Bala TS.Neurochem Int. 1998 Aug;33(2):173-7. doi: 10.1016/s0197-0186(98)00012-6.PMID: 9761461863Cite
Donevan SD, Rogawski MA.Neuroscience. 1998 Dec;87(3):615-29. doi: 10.1016/s0306-4522(98)00109-2.PMID: 9758228
Thiocyanate enhanced the rate of desensitization and slowed recovery from desensitization of AMPA-evoked currents, whereas GYKI 52466 failed to affect desensitization. Among neurons in the hippocampal cultures, there was cell-to-cell variability in the sensitivity to block …864Cite
Cyclic AMP impairs the PRL stimulation of iodide uptake into mouse mammary tissues.
Rillema JA, Marting C.Proc Soc Exp Biol Med. 1998 Oct;219(1):37-40. doi: 10.3181/00379727-219-44313.PMID: 9751220
In earlier studies the uptake of iodide into mammary cells was found to occur by a mechanism similar to that in thyroid cells (i.e., the uptake occurs via a sodium-iodide symporter that is inhibited by perchlorate and thiocyanate). Although cyclic AMP stimulates the iodide …865Cite
Tojo JL, Santamarina MT.Dis Aquat Organ. 1998 Jul 30;33(3):187-93. doi: 10.3354/dao033187.PMID: 9745715 Free article.866Cite
Ghebeh H, Handa-Corrigan A, Butler M.Anal Biochem. 1998 Aug 15;262(1):39-44. doi: 10.1006/abio.1998.2750.PMID: 9735146
The assay is based on the formation of a complex with cobalt thiocyanate as previously developed for the measurement of Pluronic in liver tissue. To adapt the assay for the lower detection levels required in cell culture medium, the absorbance of the complex was measured a …867Cite
Iodine deficiency disorders in pre-adolescent and adolescent children in Nigeria, West Africa.
Das SC, Isichei UP, Obekpa PO.West Afr J Med. 1998 Apr-Jun;17(2):113-20.PMID: 9715118
Results indicate that about 2/3 of the region is goitre endemic due principally to iodine deficiency (ID) prevailing in the region as reflected by a low drinking water iodine (DWI) concentrations throughout most of the areas surveyed as well as by a reduced urinary iodide excreti …868Cite
A fast and inexpensive method for isolation of high-quality RNA from eimerian oocysts.
Johnston DA, Bratty J, Fernando MA.Parasitol Res. 1998 Jul;84(7):549-51. doi: 10.1007/s004360050446.PMID: 9694370869Cite
Biassoni P, Ravera G, Bertocchi J, Schenone F, Bourdoux P.Eur J Endocrinol. 1998 Jun;138(6):681-5. doi: 10.1530/eje.0.1380681.PMID: 9678536 Clinical Trial.
DESIGN: Thyroid function and iodine and thiocyanate intakes were evaluated in Bororos and inhabitants of the same area and compared with an Italian population. …Compared with the reference population, the Bororos had slightly lower thyroxine (T4) and free thyroxine (FT4) …870Cite
Shin J, Bautista EM, Kang YB, Molitor TW.J Virol Methods. 1998 May;72(1):67-79. doi: 10.1016/s0166-0934(98)00025-1.PMID: 9672134871Cite
UV spectrophotometric analysis of ribonucleic acids.
Rapley R, Heptinstall J.Methods Mol Biol. 1998;86:65-8. doi: 10.1385/0-89603-494-1:65.PMID: 9664455 No abstract available.872Cite
Isolation of total RNA from tissues or cell lines. Visualization in gel.
Mukhopadhyay T, Roth JA.Methods Mol Biol. 1998;86:55-9. doi: 10.1385/0-89603-494-1:55.PMID: 9664453 No abstract available.873Cite
Isolation of total RNA from bacteria.
Heptinstall J.Methods Mol Biol. 1998;86:47-53. doi: 10.1385/0-89603-494-1:47.PMID: 9664452 No abstract available.874Cite
Extraction of RNA from fresh and frozen blood.
Theophilus BD.Methods Mol Biol. 1998;86:39-45. doi: 10.1385/0-89603-494-1:39.PMID: 9664451 No abstract available.875Cite
Isolation of plant mitochondrial RNA from green leaves.
Ye F, Abel WO, Reski R.Methods Mol Biol. 1998;86:33-8. doi: 10.1385/0-89603-494-1:33.PMID: 9664450 No abstract available.876Cite
Extraction and purification of RNA from plant tissue enriched in polysaccharides.
Cheng SH, Seemann JR.Methods Mol Biol. 1998;86:27-32. doi: 10.1385/0-89603-494-1:27.PMID: 9664449 No abstract available.877Cite
RNA extraction from formalin-fixed and paraffin-embedded tissues.
Stanta G, Bonin S, Perin R.Methods Mol Biol. 1998;86:23-6. doi: 10.1385/0-89603-494-1:23.PMID: 9664448 No abstract available.878Cite
Tojo JL, Santamarina MT.Dis Aquat Organ. 1998 May 14;33(1):51-6. doi: 10.3354/dao033051.PMID: 9653458 Free article.879Cite
Stimulated salivary flow rate and composition in asthmatic and non-asthmatic adults.
Lenander-Lumikari M, Laurikainen K, Kuusisto P, Vilja P.Arch Oral Biol. 1998 Feb;43(2):151-6. doi: 10.1016/s0003-9969(97)00110-6.PMID: 9602294
The number of decayed, missed and filled permanent teeth (DMFT), the degree of periodontal inflammation (Periodontal Status Index, PSI), stimulated salivary flow rate and the concentrations of total protein, lactoferrin, lysozyme, myeloperoxidase, salivary peroxidase, calcium, po …880Cite
Structure-activity relationship of new growth inhibitors of Trypanosoma cruzi.
Cinque GM, Szajnman SH, Zhong L, Docampo R, Schvartzapel AJ, Rodriguez JB, Gros EG.J Med Chem. 1998 Apr 23;41(9):1540-54. doi: 10.1021/jm970860z.PMID: 9554887
Of the designed compounds, sulfur-containing derivatives were shown to be potent antireplicative agents against T. cruzi. Among these drugs, 4-phenoxyphenoxyethyl thiocyanate (compound 56) proved to be an extremely active growth inhibitor of the epimastigote forms o …881Cite
Schnuch A, Geier J, Uter W, Frosch PJ.Br J Dermatol. 1998 Mar;138(3):467-76. doi: 10.1046/j.1365-2133.1998.02126.x.PMID: 9580801
Patients tested with the IB series reacted most often to methylene-bis-thiocyanate (5%), but with a reaction index of -0.7, many reactions were most probably false positives. …882Cite
Counteracting the negative effects of rapeseed and rapeseed press cake in pig diets.
Schöne F, Rudolph B, Kirchheim U, Knapp G.Br J Nutr. 1997 Dec;78(6):947-62. doi: 10.1079/bjn19970211.PMID: 9497445883Cite
The anti-prion activity of Congo red. Putative mechanism.
Caspi S, Halimi M, Yanai A, Sasson SB, Taraboulos A, Gabizon R.J Biol Chem. 1998 Feb 6;273(6):3484-9. doi: 10.1074/jbc.273.6.3484.PMID: 9452472 Free article.
The mechanism by which such anti-prion agents operate is unknown. We show here that in vitro incubation with CR renders native PrPSc resistant to denaturation by boiling SDS. …CR-PrPSc could only be denatured by the addition of acidic 3 M guanidine thiocyanate. Si …884Cite
Isolation of full-length RNA from a thermophilic cyanobacterium.
Luo XZ, Stevens SE Jr.Biotechniques. 1997 Nov;23(5):904-6, 908, 910. doi: 10.2144/97235st08.PMID: 9383558 Free article.
The assay of M. laminosus cell lysates showed that RNase activity was high and was resistant to the conventional guanidine thiocyanate and 2-mercaptoethanol denaturation methods. The mRNA isolated by several conventional methods was completely degraded. …This method coul …885Cite
[A simple method for RNA isolation and purification].
Gribanov OG, Shcherbakov AV, Perevozchikova NA, Drygin VV, Gusev AA.Bioorg Khim. 1997 Sep;23(9):763-5.PMID: 9441599 Russian.
The RNA was reversibly adsorbed on the filters in the presence of 2 M guanidine thiocyanate and 50% ethanol (or isopropanol) and eluted with water. The fraction composition of the isolated RNA depended on the guanidine thiocyanate and alcohol concentrations in the a …886Cite
Kirstilä V, Häkkinen P, Jentsch H, Vilja P, Tenovuo J.J Dent Res. 1998 Jan;77(1):73-80. doi: 10.1177/00220345980770011101.PMID: 9437402
Previous studies of the possible associations of salivary antimicrobial agents with dental caries have given controversial results, obviously mainly because almost all studies have been cross-sectional. …In spite of the above associations, we conclude that none of …887Cite
Anaerobic killing of oral streptococci by reduced, transition metal cations.
Dunning JC, Ma Y, Marquis RE.Appl Environ Microbiol. 1998 Jan;64(1):27-33. doi: 10.1128/AEM.64.1.27-33.1998.PMID: 9435058 Free PMC article.
The organism was able to take up ferrous iron, but ferric reductase activity could not be detected. Chelators, uric acid, and thiocyanate were not effective inhibitors of the lethal damage. Sulfhydryl compounds, ferricyanide, and ferrocyanide were protective if added prior …888Cite
Modified guanidinium thiocyanate method for human sperm DNA isolation.
Hossain AM, Rizk B, Behzadian A, Thorneycroft IH.Mol Hum Reprod. 1997 Nov;3(11):953-6. doi: 10.1093/molehr/3.11.953.PMID: 9433920889Cite
Antioxidative compounds isolated from safflower (Carthamus tinctorius L.) oil cake.
Zhang HL, Nagatsu A, Watanabe T, Sakakibara J, Okuyama H.Chem Pharm Bull (Tokyo). 1997 Dec;45(12):1910-4. doi: 10.1248/cpb.45.1910.PMID: 9433760
Antioxidative activities of the compounds were measured by the ferric thiocyanate method and the alpha,alpha-diphenyl-beta-picrylhydrazyl (DPPH) method, and compounds 1-5 were found to have relatively strong antioxidative activity….890Cite
Isolation of RNA from plant cell suspension cultures and calli by sonication.
Liao YC, Drossard J, Nähring JM, Fischer R.Biotechniques. 1997 Dec;23(6):996-8, 1000. doi: 10.2144/97236bm05.PMID: 9421623 Free article. No abstract available.891Cite
Ateş O, Kocabalkanli A, Saniş GO, Ekinci AC, Vidin A.Arzneimittelforschung. 1997 Oct;47(10):1134-8.PMID: 9368708
Furthermore, Ia-XIIa were refluxed with ammonium thiocyanate to give 5-phenyl/methyl-2-[(5-aryl-1,3,4-oxadiazol-2-yl)imino]-4-thiazo lidinones (It-XIIt). …892Cite
Thiocyanate and chloride as competing substrates for myeloperoxidase.
van Dalen CJ, Whitehouse MW, Winterbourn CC, Kettle AJ.Biochem J. 1997 Oct 15;327 ( Pt 2)(Pt 2):487-92. doi: 10.1042/bj3270487.PMID: 9359420 Free PMC article.
The relative specificity constants for chloride, bromide and thiocyanate were 1:60:730 respectively, indicating that thiocyanate is by far the most favoured substrate for myeloperoxidase. …The rate of H2O2 loss catalysed by myeloperoxidase in the presence of 100 m …893Cite
Peretz D, Williamson RA, Matsunaga Y, Serban H, Pinilla C, Bastidas RB, Rozenshteyn R, James TL, Houghten RA, Cohen FE, Prusiner SB, Burton DR.J Mol Biol. 1997 Oct 31;273(3):614-22. doi: 10.1006/jmbi.1997.1328.PMID: 9356250894Cite
Efficient recovery of plasmid DNA from Erwinia herbicola with high nuclease activity.
Koul S, Verma V, Kumar A, Qazi GN.Biotechniques. 1997 Oct;23(4):600-3. doi: 10.2144/97234bm08.PMID: 9343670 Free article. No abstract available.895Cite
Characteristics of the prolactin stimulation of iodide uptake into mouse mammary gland explants.
Rillema JA, Rowady DL.Proc Soc Exp Biol Med. 1997 Sep;215(4):366-9. doi: 10.3181/00379727-215-44145.PMID: 9270719
The effect of PRL apparently involves an RNA-DNA-dependent mechanism, since actinomycin D and cyclohexamide abolish the PRL stimulation of iodide uptake and its incorporation into protein. Perchlorate and thiocyanate, inhibitors of the iodide transporter, also abolish the …896Cite
Schöne F, Leiterer M, Jahreis G, Rudolph B.Zentralbl Veterinarmed A. 1997 Aug;44(6):325-39. doi: 10.1111/j.1439-0442.1997.tb01117.x.PMID: 9342925
Sow diets without supplementary iodine but containing glucosinolates (via rapeseed meal, rapeseed) caused significant reduction in thyroxine serum concentration of piglets, whereas this hormone did not change in sow serum. Thiocyanate was significantly increased in the ser …897Cite
The use of primary hepatocyte cultures for the evaluation of chemoprotective agents.
Morel F, Langouët S, Mahéo K, Guillouzo A.Cell Biol Toxicol. 1997 Jul;13(4-5):323-9. doi: 10.1023/a:1007491525955.PMID: 9298252 Review.
Recently we made use of primary hepatocytes to investigate the effects of chemoprotective agents on drug-metabolizing enzyme expression and activities. The treatment of rat and human hepatocytes with two chemoprotective agents, oltipraz (a synthetic derivative of 1, …898Cite
Ngo DB, Dikassa L, Okitolonda W, Kashala TD, Gervy C, Dumont J, Vanovervelt N, Contempré B, Diplock AT, Peach S, Vanderpas J.Trop Med Int Health. 1997 Jun;2(6):572-81. doi: 10.1046/j.1365-3156.1997.d01-326.x.PMID: 9236825 Free article.
Besides combined iodine and selenium deficiency which is permissive, another factor (thiocyanate?) must be taken into account to explain the peculiarly elevated prevalence of endemic myxoedematous cretinism in Central Africa….899Cite
Volume regulation in NIH/3T3 cells not expressing P-glycoprotein. I. Regulatory volume decrease.
Pasantes-Morales H, Sánchez Olea R, Miranda D, Morán J.Am J Physiol. 1997 Jun;272(6 Pt 1):C1798-803. doi: 10.1152/ajpcell.1997.272.6.C1798.PMID: 9227407
Most anions were able to permeate, with a permeability ranking of nitrate > benzoate = iodide > thiocyanate > chloride > > gluconate. The pathway was permeable to neutral amino acids, with a permeability ranking of glycine > alanine > glutamate > ta …900Cite
Xin H, Leanza K, Spremulli LL.Biochim Biophys Acta. 1997 May 2;1352(1):102-12. doi: 10.1016/s0167-4781(97)00003-1.PMID: 9177488
The EF-Tu(Eco) x Ts(mt) complex can be dissociated by denaturation using 2 M guanidine thiocyanate. Free EF-Ts(mt) can then be purified and renatured. The refolded EF-Ts(mt) is active in stimulating the activity of expressed mitochondrial EF-Tu (EF-Tu(mt)) in poly(U)-direc …901Cite
May SL, May WA, Bourdoux PP, Pino S, Sullivan KM, Maberly GF.Am J Clin Nutr. 1997 May;65(5):1441-5. doi: 10.1093/ajcn/65.5.1441.PMID: 9129474
There were no apparent effects on the method by thiocyanate, a known interfering substance. In a comparison with five other methods performed in four different laboratories, samples were collected to test the method performance over a wide range of urinary iodine values (0 …902Cite
Adak S, Mazumdar A, Banerjee RK.J Biol Chem. 1997 Apr 25;272(17):11049-56. doi: 10.1074/jbc.272.17.11049.PMID: 9110998 Free article.
The one-electron oxidation product of SCN- was identified by electron spin resonance spectroscopy as 5-5-dimethyl-1-pyrroline N-oxide adduct of the sulfur-centered thiocyanate radical (aN = 15.0 G and abetaH = 16.5 G). The inactivation of the enzyme in the presence of SCN- …903Cite
Crystal structure of the gramicidin/potassium thiocyanate complex.
Doyle DA, Wallace BA.J Mol Biol. 1997 Mar 14;266(5):963-77. doi: 10.1006/jmbi.1996.0837.PMID: 9086274
The crystal structure of the gramicidin/potassium thiocyanate complex (a = 32.06 A, b = 51.80 A, and c = 31.04 A; space group P2(1)2(1)2(1)) has been solved to 2.5 A with an R-factor of 0.193. …904Cite
Lynch E, Sheerin A, Claxson AW, Atherton MD, Rhodes CJ, Silwood CJ, Naughton DP, Grootveld M.Free Radic Res. 1997 Mar;26(3):209-34. doi: 10.3109/10715769709097801.PMID: 9161844
Experiments conducted on chemical model systems confirmed the oxidative decarboxylation of pyruvate by this oral rinse, and also demonstrated that urate, thiocyanate anion, and the amino acids cysteine and methionine (precursors to volatile sulphur compounds responsible fo …905Cite
DNAzol: a reagent for the rapid isolation of genomic DNA.
Chomczynski P, Mackey K, Drews R, Wilfinger W.Biotechniques. 1997 Mar;22(3):550-3. doi: 10.2144/97223pf01.PMID: 9067036 Free article.
In this report, we present DNAzol, a patent-pending DNA isolation reagent containing guanidine thiocyanate and a detergent mixture. It is a complete, nontoxic and ready-to-use reagent for the isolation of genomic DNA from various biological sources. …906Cite
Ramadan AM.J Inorg Biochem. 1997 Feb 15;65(3):183-9. doi: 10.1016/s0162-0134(96)00122-5.PMID: 9025270
In the case of hexa coordinate complexes, in which nitrate, sulphate, or thiocyanate is attached to a copper(II) ion in a 1:2 (metal:ligand) ratio, a distorted octahedral geometry around copper(II) is proposed. The antimicrobial activity of the free ligand and its c …907Cite
Decontamination of Creutzfeldt-Jakob disease and other transmissible agents.
Manuelidis L.J Neurovirol. 1997 Feb;3(1):62-5. doi: 10.3109/13550289709015793.PMID: 9147822
Tissue from established but undiagnosed human infections can contaminate medical supplies and instruments. We tested guanidine thiocyanate (GdnSCN) solutions and found them to be highly effective in disrupting the infectious agent, even in very complex tissues such as whol …908Cite
Popper L, Knorr D.Nahrung. 1997 Feb;41(1):29-33. doi: 10.1002/food.19970410108.PMID: 9113668
The antifungal activity of the combined enzyme system was tested with initial counts of approx. 10(5) cfu.ml-1 (yeast cells or spores) suspended in salt solution supplemented with 25 mg.l-1 thiocyanate and 20 g.l-1 glucose or in apple juice supplemented with the same amoun …909Cite
Salivary parameters of relevance for assessing caries activity in individuals and populations.
Tenovuo J.Community Dent Oral Epidemiol. 1997 Feb;25(1):82-6. doi: 10.1111/j.1600-0528.1997.tb00903.x.PMID: 9088696 Review.
Although important for dental health, none of the salivary antimicrobial agents as such has shown any strong association with caries activity. The only ones with some evidence of a regulatory role are secretory IgA antibodies, hypothiocyanite ions, and agglutinins. …910Cite
Azcurra AI, Calamari SE, Yankilevich ER, Battellino LJ, Cattoni ST, Colantonio G.Acta Physiol Pharmacol Ther Latinoam. 1997;47(4):211-20.PMID: 9504181 Clinical Trial. Spanish.
The present work describes and analyzes the results of a randomized clinical trial on adolescents (age 18.2 +/- 0.6) carried out in order to evaluate the effects of a twice daily mouthrinse application containing xylitol, sorbitol, sacarine, ciclamate, aspartame, chlorhexidine, h …911Cite
[Criteria for selection of lactobacilli for probiotic use].
Nemcová R.Vet Med (Praha). 1997 Jan;42(1):19-27.PMID: 9123779 Review. Slovak.
The hydrogen peroxide along with lactoperoxidase-thiocyanate milk system exerts bacteriocid effects on most pathogens. The production of organic acids (lactic, acetic) by lactobacilli is considered to be the primary regulator of the gut microbial activity in animals. …912Cite
Makowski GS, Davis EL, Hopfer SM.J Clin Lab Anal. 1997;11(2):87-93. doi: 10.1002/(sici)1098-2825(1997)11:2<87::aid-jcla4>3.0.co;2-h.PMID: 9058242 Free PMC article.
For this purpose we evaluated guanidine thiocyanate-impregnated filter paper (GT-903), a DNA collection device designed specifically to bind PCR inhibitors and preserve DNA in an aqueous extractable form. …913Cite
Beaulieux F, See DM, Leparc-Goffart I, Aymard M, Lina B.Res Virol. 1997 Jan-Feb;148(1):11-5. doi: 10.1016/s0923-2516(97)81906-1.PMID: 9017827
RNA was extracted using labelled beads or guanidium thiocyanate-phenol-chloroform from 1, 0.1 and 0.01 TCID50/100 microliters of stock coxsackievirus types A9 and B3, echovirus type 11, enterovirus type 70 and poliovirus type 1. …914Cite
Saliva composition in children and young adults with Papillon-Lefèvre syndrome.
Lundgren T, Twetman S, Johansson I, Crossner CG, Birkhed D.J Clin Periodontol. 1996 Dec;23(12):1068-72. doi: 10.1111/j.1600-051x.1996.tb01805.x.PMID: 8997649
The stimulated saliva was assessed for buffer capacity, total protein, peroxidase and hexosamine, while the unstimulated samples were evaluated for total protein, lysozyme, thiocyanate, lactoferrin and salivary IgA. Both the unstimulated (p < 0.01) and stimulated (p <…915Cite
Kirstilä V, Lenander-Lumikari M, Söderling E, Tenovuo J.Acta Odontol Scand. 1996 Dec;54(6):391-7. doi: 10.3109/00016359609003557.PMID: 8997439 Clinical Trial.
This study evaluates the effects of two oral hygiene products containing nonimmunoglobulin antimicrobial agents on whole saliva and on subjective oral symptoms in patients with xerostomia. …The products relieved subjective oral symptoms in most xerostomic patients …916Cite
Milling reduces the goitrogenic potential of cassava.
Mlingi ML, Bokanga M, Kavishe FP, Gebre-Medhin M, Rosling H.Int J Food Sci Nutr. 1996 Nov;47(6):445-54. doi: 10.3109/09637489609031873.PMID: 8933198
Cyanide exposure from consumption of insufficiently processed cassava has been implicated in aggravating iodine deficiency disorders (IDD). The cyanide metabolite, thiocyanate (SCN) may interfere with iodine (I) uptake of the thyroid gland. A study on 217 women in an IDD e …917Cite
A review of countermeasures to reduce radioiodine in milk of dairy animals.
Howard BJ, Voigt G, Segal MG, Ward GM.Health Phys. 1996 Nov;71(5):661-73. doi: 10.1097/00004032-199611000-00005.PMID: 8887510
Other compounds, such as perchlorate and thiocyanate, also reduce the transfer to radioiodine to milk (and thyroid). Some of these compounds seem to be potentially equally as effective as stable iodine. …918Cite
Nishioka T, Kimura M, Takahama U.Arch Oral Biol. 1996 Oct;41(10):911-7. doi: 10.1016/s0003-9969(96)00058-1.PMID: 9031698
The optimum pH was around pH 6. Sodium thiocyanate inhibited the oxygen evolution under acidic conditions in dialysed saliva, increasing the K(m) of hydrogen peroxide and decreasing the Vmax. …919Cite
Longitudinal study on goiter prevalence and goitrogen factors in northeastern Sicily.
Regalbuto C, Squatrito S, La Rosa GL, Cercabene G, Ippolito A, Tita P, Salamone S, Vigneri R.J Endocrinol Invest. 1996 Oct;19(9):638-45. doi: 10.1007/BF03349031.PMID: 8957750
Biochemical studies were also performed on urinary iodine and thiocyanate (SCN) excretion and 131I thyroid uptake. In the town of Troina an experimental program of active iodine prophylaxis was carried out from 1979 to 1987 by iodinating the municipal water supply. …920Cite
Prevalence of iodine deficiency disorders and goitre in Chad.
Wyss K, Guiral C, Ndikuyeze A, Malonga G, Tanner M.Trop Med Int Health. 1996 Oct;1(5):723-9. doi: 10.1111/j.1365-3156.1996.tb00101.x.PMID: 8911460 Free article.
In the Sahel zone and in N’Djamena the figures reached 8 and 1%. There were high levels of thiocyanate anions in urine reaching medians between 21 and 27 mg/l in the geographical stratas. …921Cite
Copper-release from yeast Cu(I)-thionein by hypothiocyanite (OSCN-).
Hartmann HJ, Deters D, Weser U.Biometals. 1996 Oct;9(4):345-9. doi: 10.1007/BF00140603.PMID: 8837455
In the course of an oxidative burst oxygen free radicals and hypothiocyanite (OSCN-), a transiently abundant derivative of thiocyanate (SCN-), are formed in the presence of activated polymorphonuclear leukocytes (PMNs). At the same time Cu(I)-thionein is present and the qu …922Cite
Bala TS, Janardanasarma MK, Raghunath M.Int J Dev Neurosci. 1996 Aug;14(5):575-83.PMID: 8930689
The hypothesis that a defect in the rate-limiting blood-brain barrier (BBB) nutrient transport may be one of the factors responsible for the brain defects seen in some iodine deficiency disorders was tested in Wistar/NIN rats fed potassium thiocyanate (KSCN), a synthetic g …923Cite
Modification of the acid guanidinium thiocyanate-phenol-chloroform method for nuclear RNA isolation.
Vareli K, Frangou-Lazaridis M.Biotechniques. 1996 Aug;21(2):236-7. doi: 10.2144/96212bm15.PMID: 8862807 Free article. No abstract available.924Cite
Kirstilä V, Tenovuo J, Ruuskanen O, Suonpää J, Meurman O, Vilja P.Clin Immunol Immunopathol. 1996 Aug;80(2):110-5. doi: 10.1006/clin.1996.0103.PMID: 8764554 Clinical Trial.
Saliva samples were analyzed for selected host defense factors, representing both immune (total IgA, IgG, IgM, anti-Streptococcus mutans, anti-EBV, anti-CMV, and anti-adenovirus IgA and IgG) and nonimmunoglobulin (lysozyme, lactoferrin, salivary peroxidases, thiocyanate, h …925Cite
Fei P, Matwyshyn GA, Rushmore TH, Kong AN.Pharm Res. 1996 Jul;13(7):1043-8. doi: 10.1023/a:1016006707613.PMID: 8842042
PURPOSE: To study the transcription regulation of rat glutathione S-transferase Ya (rGSTya) subunit gene expression by chemopreventive agents. METHODS: The effects of chemopreventive agents; tamoxifen, genistein, oltipraz, indole-3-carbinol, and various isothiocyana …926Cite
Preferential interaction of denaturants with rice bran lipase.
Rajeshwara AN, Gopalakrishna KN, Prakash V.Int J Biol Macromol. 1996 Jul;19(1):1-7. doi: 10.1016/0141-8130(96)01091-4.PMID: 8782712927Cite
Fekkes D.J Chromatogr B Biomed Appl. 1996 Jun 28;682(1):3-22. doi: 10.1016/0378-4347(96)00057-6.PMID: 8832421 Review.928Cite
Connern CP, Halestrap AP.Biochemistry. 1996 Jun 25;35(25):8172-80. doi: 10.1021/bi9525177.PMID: 8679570
The action of KSCN could be mimicked by guanidinium chloride, implying that the chaotropic action of these agents stabilized the bound complex. The sensitivity to [Ca2+] of the MTP in deenergized mitochondria was greatly enhanced in KSCN medium as compared to KCl medium. . …929Cite
Cuprous ions activate glibenclamide-sensitive potassium channel in liver mitochondria.
Wojtczak L, Nikitina ER, Czyz A, Skulskii IA.Biochem Biophys Res Commun. 1996 Jun 14;223(2):468-73. doi: 10.1006/bbrc.1996.0917.PMID: 8670305
Cuprous ions at micromolar concentrations induced swelling of rat liver mitochondria in isotonic solutions of potassium thiocyanate and potassium acetate. The swelling in K-acetate in the presence of the protonophore [corrected] carbonyl cyanide m-chloropenylhydrazone was …930Cite
Thiocyanate-independent nitrosation in humans with carcinogenic parasite infection.
Satarug S, Haswell-Elkins MR, Tsuda M, Mairiang P, Sithithaworn P, Mairiang E, Esumi H, Sukprasert S, Yongvanit P, Elkins DB.Carcinogenesis. 1996 May;17(5):1075-81. doi: 10.1093/carcin/17.5.1075.PMID: 8640916
This suggests that considerable generation of nitrosating agents (N203/N204) in infected people may be occurring via oxidation of arginine by nitric oxide synthase in inflamed tissue which is thiocyanate insensitive. …New information is also provided on the determ …931Cite
Hale AD, Green J, Brown DW.J Virol Methods. 1996 Apr 5;57(2):195-201. doi: 10.1016/0166-0934(95)01966-9.PMID: 8801231
RNA extraction using the metal chelating agent Chelex-100 and Sephadex G200 column chromatography were the most sensitive, detecting a 10(-4) dilution of a known SRSV positive specimen. Guanidinium thiocyanate (GTC) with adsorption of viral RNA onto silica was 10-fold less …932Cite
Purification of NADH: hypothiocyanite oxidoreductase in Streptococcus sanguis.
Courtois PH, Pourtois M.Biochem Mol Med. 1996 Apr;57(2):134-8. doi: 10.1006/bmme.1996.0019.PMID: 8733891933Cite
Inhibition of catalase activity in vitro by diesel exhaust particles.
Mori Y, Murakami S, Sagae T, Hayashi H, Sakata M, Sagai M, Kumagai Y.J Toxicol Environ Health. 1996 Feb 9;47(2):125-34. doi: 10.1080/009841096161834.PMID: 8598569
The inhibition of catalase by DEP was observed only in the presence of anions such as Cl-,Br-, or thiocyanate. Other anions, such as CH3COO- or SO4-, and cations such as K+, Na+, Mg2+, or Fe2+, did not affect the activity of catalase, even in the presence of DEP extract. . …934Cite
Potentially prebiotic syntheses of condensed phosphates.
Keefe AD, Miller SL.Orig Life Evol Biosph. 1996 Feb;26(1):15-25. doi: 10.1007/BF01808157.PMID: 11536744935Cite
Isocratic high-performance liquid chromatographic determination of tryptophan in infant formulas.
Alegría A, Barberá R, Farré R, Ferrerés M, Lagarda MJ, López JC.J Chromatogr A. 1996 Jan 15;721(1):83-8. doi: 10.1016/0021-9673(95)00629-x.PMID: 8653197936Cite
Oxazolidonylethyl adducts to hemoglobin and DNA following nornitrogen mustard exposure.
Thulin H, Zorcec V, Segerbäck D, Sundwall A, Törnqvist M.Chem Biol Interact. 1996 Jan 5;99(1-3):263-75. doi: 10.1016/0009-2797(95)03674-1.PMID: 8620574937Cite
[Control of buccal peroxidases by a bacterial NADH-hypothiocyanite oxidoreductase].
Courtois P.Bull Mem Acad R Med Belg. 1996;151(12):511-6.PMID: 9491629 French.
Oral peroxidases (myeloperoxidase, sialoperoxidase) catalyze thiocyanate peroxidation into hypothiocyanite which is bacteriostatic or bactericidal against numerous bacterial species. …938Cite
[Modifying effects of goitrogens on the tumor development in the liver and lung of rats].
Takegawa K, Mitsumori K, Onodera H, Shimo T, Takahashi M, Yasuhara K, Takahashi M.Eisei Shikenjo Hokoku. 1996;(114):33-7.PMID: 9037862 Japanese.
In order to investigate whether goitrogens and liver enzyme-inducers modify the tumorigenesis in the liver or lung, 6-week old male F344 rats were given single subcutaneous injection of DHPN, and starting one week later received water containing goitrogens, namely sulfadimethoxin …939Cite
Antifungal screening of seven new azole derivatives.
Mares D, Romagnoli C, Vicentini CB, Sacchetti G, Bruni A.Microbios. 1996;86(348):185-93.PMID: 8885417
The 4-methyl-6-phenyl-pyrazolo[3,4-d] [1,2,3]triazole produced only a partial inhibition of growth, whereas the most active compounds were the two thiadiazines (6H-3-phenyl-5-methyl-7-(3,4-dichlorophenyl)pyrazolo[3,4-c] [1,2,5]thiadiazine-2,2-dioxide and 7-methyl-2-phenyl-4H-pyra …940Cite
Mäkinen KK, Chen CY, Mäkinen PL, Bennett CA, Isokangas PJ, Isotupa KP, Pape HR Jr.Caries Res. 1996;30(3):180-8. doi: 10.1159/000262157.PMID: 8860027941Cite
Manninen A, Auriola S, Vartiainen M, Liesivuori J, Turunen T, Pasanen M.Arch Toxicol. 1996;70(9):579-84. doi: 10.1007/s002040050315.PMID: 8831908942Cite
Virucidal effect of stimulated eosinophils on human immunodeficiency virus type 1.
Klebanoff SJ, Coombs RW.AIDS Res Hum Retroviruses. 1996 Jan 1;12(1):25-9. doi: 10.1089/aid.1996.12.25.PMID: 8825615
Eosinophils, when stimulated, release a variety of agents that can be toxic to ingested or extracellular targets. Among these systems is one that consists of eosinophil peroxidase (EPO), H2O2, and a halide. …When the EPO concentration is suboptimal, virucidal activity is …943Cite
Mihaljević B, Katusin-Razem B, Razem D.Free Radic Biol Med. 1996;21(1):53-63. doi: 10.1016/0891-5849(95)02224-4.PMID: 8791093
The mechanistic aspects of the spectrophotometric method of analysis of lipid hydroperoxides (LOOH) based on the oxidation of ferrous to ferric ion and subsequent complexation of the latter by thiocyanate are considered. The method of analysis, as revised by us, was carrie …944Cite
Atom level electrotopological state indexes in QSAR: designing and testing antithyroid agents.
Abou-Shaaban RR, al-Khamees HA, Abou-Auda HS, Simonelli AP.Pharm Res. 1996 Jan;13(1):129-36. doi: 10.1023/a:1016049921842.PMID: 8668662
PURPOSE: To design antithyroid agents with less side effects, the electrotopological-state (E-state) indexes of thiourylene moiety (SN&S) was utilized as a guideline to develop five acrylic thiourylene-type compounds with reduced antioxidant property. METHODS: These …945Cite
Kaabache T, Barraud B, Feldmann G, Bernuau D, Lardeux B.Anal Biochem. 1995 Dec 10;232(2):225-30. doi: 10.1006/abio.1995.0011.PMID: 8747479
The sensitivity of direct solution hybridization of hepatocytes solubilized in guanidium thiocyanate (GuSCN) for detecting alpha 1-acid glycoprotein and albumin mRNAs was studied. …946Cite
Genotoxicity of potential metabolites of nitroscanate–an antischistosomal drug.
Gupta RL, Kaur IP, Juneja TR.Mutat Res. 1995 Dec;335(3):235-43. doi: 10.1016/0165-1161(95)90045-4.PMID: 8524338947Cite
Whittingham JL, Chaudhuri S, Dodson EJ, Moody PC, Dodson GG.Biochemistry. 1995 Nov 28;34(47):15553-63. doi: 10.1021/bi00047a022.PMID: 7492558
The R factors for the refined structures of thiocyanate insulin, methylparaben insulin, and phenol insulin were 19.6, 18.4, and 19.1, respectively. Each crystal structure consists of T3R3f insulin hexamers with two zinc ions per hexamer. In the R3f trimer of the thiocya …948Cite
Oxygen dependence of hepatocyte susceptibility to mitochondrial respiratory inhibitors.
Niknahad H, Khan S, O’Brien PJ.Biochem Pharmacol. 1995 Nov 27;50(11):1859-65. doi: 10.1016/0006-2952(95)02079-9.PMID: 8615865
CN but not AA depleted ATP levels of hepatocytes more extensively at 1% than at 95% O2. The CN-trapping agents dihydroxyacetone, glyceraldehyde, alpha-ketoglutarate and pyruvate prevented CN-induced cytotoxicity more effectively at 95% O2 than at 1% O2. In contrast, thiosu …949Cite
Xie J, Drumm ML, Ma J, Davis PB.J Biol Chem. 1995 Nov 24;270(47):28084-91. doi: 10.1074/jbc.270.47.28084.PMID: 7499295 Free article.950Cite
Role of goitrogens in iodine deficiency disorders & brain development.
Rao PS, Lakshmy R.Indian J Med Res. 1995 Nov;102:223-6.PMID: 8675242 Review.
Detailed experimental studies were undertaken to ascertain various biochemical changes associated with developing brain in response to treatment with a goitrogens–thiocyanate. Addition of thiocyanate to food deprived of KI brought down significantly the circulating …951Cite
Petersen NE, Larsen LK, Nissen H, Jensen LG, Jensen A, Hyltoft Petersen P, Hørder, Gregersen N, Kristiansen K.Clin Chem. 1995 Nov;41(11):1605-13.PMID: 7586550
Instead of precipitation and extraction with phenol and chloroform, we use a faster and more reliable precipitation based on guanidinium thiocyanate (GdSCN). The internal standard is produced by in vitro transcription of a DNA template constructed so as to allow simultaneo …952Cite
Lakshmy R, Rao PS, Sesikeran B, Suryaprakash P.Horm Metab Res. 1995 Oct;27(10):450-4. doi: 10.1055/s-2007-980000.PMID: 8575723
On a moderate intake of iodine (by depriving diet of KI) 25 mg of thiocyanate or substitution of 1/3rd proportion of casein based diet with dry cabbage, could significantly reduce plasma thyroxine level by 60 days. …Semi quantitative assessment of thyroid, indicated hypo …953Cite
Effect of oxygen and sodium thiosulfate during combined carbon monoxide and cyanide poisoning.
Breen PH, Isserles SA, Westley J, Roizen MF, Taitelman UZ.Toxicol Appl Pharmacol. 1995 Oct;134(2):229-34. doi: 10.1006/taap.1995.1188.PMID: 7570599
Treatment with oxygen and Na2S2O3 did not hasten the recovery of this lactic acidosis or decrease blood cyanide levels compared to nontreated dogs. However, after treatment, plasma thiocyanate significantly increased from 16.3 +/- 12.5 to 94.4 +/- 72.2 microM, as Na2S2O3 p …954Cite
Nielsen EO, Johansen TH, Wätjen F, Drejer J.J Neurochem. 1995 Sep;65(3):1264-73. doi: 10.1046/j.1471-4159.1995.65031264.x.PMID: 7543932
The binding of [3H]NS 257 (1,2,3,6,7,8-hexahydro-3-(hydroxyimino)-N,N-[3H]dimethyl-7-methyl- 2- oxobenzo[2,1-b:3,4-c’]dipyrrole-5-sulfonamide) to rat cortical membranes was characterized in the absence and presence of thiocyanate. Specific [3H]NS 257 binding was saturable …955Cite
RNA extraction from gastrointestinal tract and pancreas by a modified Chomczynski and Sacchi method.
Monstein HJ, Nylander AG, Chen D.Biotechniques. 1995 Sep;19(3):340-4.PMID: 7495539 No abstract available.956Cite
A simple procedure for gel electrophoresis and northern blotting of RNA.
Goda SK, Minton NP.Nucleic Acids Res. 1995 Aug 25;23(16):3357-8. doi: 10.1093/nar/23.16.3357.PMID: 7545288 Free PMC article.957Cite
Effect of saliva composition on growth of Candida albicans and Torulopsis glabrata.
Lenander-Lumikari M, Johansson I.Oral Microbiol Immunol. 1995 Aug;10(4):233-40. doi: 10.1111/j.1399-302x.1995.tb00148.x.PMID: 8602336
We have sought a possible relationship between indigenous salivary constituents, including antimicrobial and nutritive factors, and the growth rate and/or viability of inoculated fungi in glucose-supplemented sterilized saliva. …Besides a 4% reduction in calcium (Ca2+) a …958Cite
Use of Multiscreen plates for the preparation of bacterial DNA suitable for PCR.
Reek FH, Smits MA, Kamp EM, Smith HE.Biotechniques. 1995 Aug;19(2):282-5.PMID: 8527150
The method is based on the guanidinium thiocyanate (GuSCN)-lysis method of Boom et al. (J. Clin. Microbiol. 28:495-503, 1990) and enables a multiple of 96 samples to be prepared in only one hour. …959Cite
Löhr HF, Goergen B, Meyer zum Büschenfelde KH, Gerken G.J Med Virol. 1995 Aug;46(4):314-20. doi: 10.1002/jmv.1890460405.PMID: 7595407
Nucleic acids were extracted by the guanidine-thiocyanate-method, and plus- and minus-stranded HCV-RNAs were determined using primers from the 5′-untranslated region of HCV. …960Cite
Tenovuo J, Hannuksela S, Lenander-Lumikari M.Eur J Oral Sci. 1995 Aug;103(4):247-52. doi: 10.1111/j.1600-0722.1995.tb00168.x.PMID: 7552957
This study was aimed to analyze whether delmopinol (0.0032-0.65 mM) interferes with the activity of two surface-active oral antimicrobial enzymes, salivary peroxidase and lysozyme. In addition to human whole saliva (pH 5.0 and 6.0), the experiments were done in 0.1 M phosp …961Cite
Mutagenicity of nitroscanate, an antischistosomal drug.
Gupta RL, Kaur IP, Juneja TR.Mutat Res. 1995 Jun;334(3):273-81. doi: 10.1016/0165-1161(95)90064-0.PMID: 7753091962Cite
Steer BA, Merrill AR.Biochemistry. 1995 May 30;34(21):7225-33. doi: 10.1021/bi00021a038.PMID: 7766633963Cite
Casas I, Powell L, Klapper PE, Cleator GM.J Virol Methods. 1995 May;53(1):25-36. doi: 10.1016/0166-0934(94)00173-e.PMID: 7635925
The technique involves a single extraction with a guanidinium thiocyanate acid (GuSCN) buffer, and does not require the use of organic solvents. Applied to the recovery of enteroviral RNA, herpes simplex virus (HSV) and Varicella-zoster virus (VZV) DNAs the method has prov …964Cite
Automated measurement of urinary iodine with use of ultraviolet irradiation.
Tsuda K, Namba H, Nomura T, Yokoyama N, Yamashita S, Izumi M, Nagataki S.Clin Chem. 1995 Apr;41(4):581-5.PMID: 7720250
The theoretical values were recovered when UV irradiation was used but not in its absence. High (supraphysiological) doses of thiocyanate or ascorbic acid, which are major interfering substances to the ceric-arsenious acid reaction, did not interfere with this system. …965Cite
Extracellular adenosine triphosphate. A shock to hemopoietic cells.
Nijweide PJ, Modderman WE, Hagenaars CE.Clin Orthop Relat Res. 1995 Apr;(313):92-102.PMID: 7641503
A short treatment of cell populations isolated from bone, bone marrow, or cartilage with 2 mM adenosine triphosphate and 1 mM of cytotoxic, but not permeant, potassium thiocyanate obliterates all cells of hemopoietic origin, including macrophages, osteoclasts, and their pr …966Cite
Kocabiyik S.Biotechniques. 1995 Apr;18(4):570-2.PMID: 7541212 No abstract available.967Cite
Mikola H, Waris M, Tenovuo J.Antiviral Res. 1995 Mar;26(2):161-71. doi: 10.1016/0166-3542(94)00073-h.PMID: 7605114
However, little is known of the actual antiviral agents in saliva. We have analyzed how hypothiocyanite (HOSCN/-OSCN) ions, present in human saliva and generated by salivary peroxidase systems, affect the viability of three different types of viruses; HSV-1 (capable of ind …968Cite
Recovery of RNA from oral streptococci.
Lunsford RD.Biotechniques. 1995 Mar;18(3):412-4.PMID: 7540019 No abstract available.969Cite
Peterson S, Rosling H, Tylleskär T, Gebre-Medhin M, Taube A.Lancet. 1995 Feb 25;345(8948):513-4; author reply 514-5.PMID: 7861885 No abstract available.970Cite
Zhang GH, Arreola J, Melvin JE.Arch Oral Biol. 1995 Feb;40(2):111-8. doi: 10.1016/0003-9969(94)00151-z.PMID: 7794125
Thiocyanate (SCN-) plays a critical part in an oral antimicrobial system by acting as a substrate for peroxidases. …971Cite
Endemic goiter in the Jos Plateau region of northern Nigeria.
Isichei UP, Morimoto I, Das SC, Egbuta JO, Banwo AI, Nagataki S.Endocr J. 1995 Feb;42(1):23-9. doi: 10.1507/endocrj.42.23.PMID: 7599694 Free article.
This study is an endemic goiter survey of 3476 school children in 13 Local Government Councils (LGCs) and 1004 subjects in a whole community of one LGC, Plateau State, Northern Nigeria, to determine the prevalence of goiter as well as to identify some of the etiological agents …972Cite
Thiocyanate, a plausible physiological electron donor of gastric peroxidase.
Das D, De PK, Banerjee RK.Biochem J. 1995 Jan 1;305 ( Pt 1)(Pt 1):59-64. doi: 10.1042/bj3050059.PMID: 7826354 Free PMC article.973Cite
Hydrogen peroxide-induced luminescence and evolution of molecular oxygen in human saliva.
Kou F, Takahama U.Arch Oral Biol. 1995 Jan;40(1):15-21. doi: 10.1016/0003-9969(94)00149-6.PMID: 7748108974Cite
The iodide channel of the thyroid. II. Selective iodide conductance inserted into liposomes.
Golstein PE, Sener A, Beauwens R.Am J Physiol. 1995 Jan;268(1 Pt 1):C111-8. doi: 10.1152/ajpcell.1995.268.1.C111.PMID: 7530906975Cite
Effects of a lactoperoxidase-system-containing toothpaste on dental plaque and whole saliva in vivo.
Kirstilä V, Lenander-Lumikari M, Tenovuo J.Acta Odontol Scand. 1994 Dec;52(6):346-53. doi: 10.3109/00016359409029032.PMID: 7887144 Clinical Trial.
Saliva was analyzed for hypothiocyanite (HOSCN/OSCN-) and thiocyanate (SCN-) concentrations and salivary peroxidase activity. The amount of total streptococci, mutans streptococci, lactobacilli, and total anaerobic flora was determined both in saliva and in plaque samples. …976Cite
Concentrations of thiocyanate and hypothiocyanite in the saliva of young adults.
Jalil RA.J Nihon Univ Sch Dent. 1994 Dec;36(4):254-60. doi: 10.2334/josnusd1959.36.254.PMID: 7869127
The study was conducted to determine thiocyanate (SCN-) and hypothiocyanite (OSCN-) concentrations in resting (RWS) and stimulated whole saliva (SWS) and stimulated parotid saliva (SPS) of 20 healthy young adults aged 21-29 y. …977Cite
[Effectiveness of Rhodovet for the prevention of coli enterotoxemia in a swine breeding facility].
Seyfarth D, Hörügel K, Grohs G.Berl Munch Tierarztl Wochenschr. 1994 Dec;107(12):416-8.PMID: 7717961 German.
With the daily oral application of Rhodovet, a drug containing thiocyanate, in doses of 3.5 kg/t feed during 5 weeks the morbidity resp. mortality could be decisively reduced….978Cite
Martin RK, Archer KT, Tuttle RM.Diagn Mol Pathol. 1994 Dec;3(4):233-9.PMID: 7532529
We employed a modification of the acid guanidium thiocyanate-phenol-chloroform extraction method for the recovery of total RNA from formalin-fixed, paraffin-embedded neoplastic thyroid tissue. …979Cite
Eosinophil peroxidase-dependent hydroxyl radical generation by human eosinophils.
McCormick ML, Roeder TL, Railsback MA, Britigan BE.J Biol Chem. 1994 Nov 11;269(45):27914-9.PMID: 7961724 Free article.980Cite
Caesium-binding sites in the gramicidin pore.
Doyle DA, Wallace BA.Biochem Soc Trans. 1994 Nov;22(4):1043-5. doi: 10.1042/bst0221043.PMID: 7535256 No abstract available.981Cite
Biotransformation of benzyl thiocyanate by Streptomyces aureofaciens.
Fuska J, Sturdíkovă M, Proksa B.Lett Appl Microbiol. 1994 Sep;19(3):124-5. doi: 10.1111/j.1472-765x.1994.tb00922.x.PMID: 7765389
Benzyl thiocyanate, a specific stimulator of chlortetracycline biosynthesis, was transformed into dibenzyl disulphide by Streptomyces aureofaciens. The disulphide stimulated chlortetracycline production to a lesser extent than did benzyl thiocyanate….982Cite
Interaction of guanidine hydrochloride and guanidine thiocyanate with wheat germ lipase.
Rajeshwara AN, Prakash V.Indian J Biochem Biophys. 1994 Aug;31(4):315-21.PMID: 8002014
Effect of two classical and potent denaturants, guanidine hydrochloride (GuHCl) and guanidine thiocyanate (GuHSCN) on purified wheat germ lipase has been studied. Lipase was found to be active only up to 5 M GuHCl and 1.5 M GuHSCN. …983Cite
A lysate ribonuclease protection assay.
Klassy RC.Am Biotechnol Lab. 1994 Aug;12(9):28.PMID: 7520706 No abstract available.984Cite
Salivary defense factors and oral health in patients with common variable immunodeficiency.
Kirstilä V, Tenovuo J, Ruuskanen O, Nikoskelainen J, Irjala K, Vilja P.J Clin Immunol. 1994 Jul;14(4):229-36. doi: 10.1007/BF01552309.PMID: 7929697
However, the occurrence of nonimmunoglobulin (innate) antimicrobial agents in saliva of these patients is virtually unknown. Therefore, we analyzed both immune (total IgA, IgG, IgM, anti-Streptococcus mutans IgA, IgG, and IgM antibodies) and nonimmune (lysozyme, lac …985Cite
[Evaluation of 4 vermifuges against Bothriocephalus acheilognathi in carp].
Flores-Crespo J, Flores-Crespo R, Ibarra-Velarde F, Vera-Montenegro Y.Rev Latinoam Microbiol. 1994 Jul-Sep;36(3):197-203.PMID: 7709095 Clinical Trial. Spanish.986Cite
Kainate binding to the AMPA receptor in rat brain.
Hall RA, Kessler M, Lynch G.Neurochem Res. 1994 Jun;19(6):777-82. doi: 10.1007/BF00967719.PMID: 7520541
The Ki value for the high-affinity component of these two-site fits was 3-9 microM and the low-affinity component Ki was in the range of 70-120 microM; similar values were determined for kainate displacement of [3H]CNQX. The presence of thiocyanate ions had no effect on ka …987Cite
Wu TY, Chang YC.Biochem J. 1994 Jun 1;300 ( Pt 2)(Pt 2):365-71. doi: 10.1042/bj3000365.PMID: 7516151 Free PMC article.988Cite
Properties of the scrapie prion protein: quantitative analysis of protease resistance.
Oesch B, Jensen M, Nilsson P, Fogh J.Biochemistry. 1994 May 17;33(19):5926-31. doi: 10.1021/bi00185a033.PMID: 7910036
PrPSc was rendered completely protease-sensitive at alkaline pH or in > 1.5 M guanidinium thiocyanate (GdnSCN). Denaturation in 4 M GdnSCN completely abolished the protease resistance of PrPSc within 15 min, while denaturation in 7.2 M urea showed a slower time course. …989Cite
Housley GD, Batcher S, Kraft M, Ryan AF.Hear Res. 1994 May;75(1-2):47-53. doi: 10.1016/0378-5955(94)90054-x.PMID: 7520901
Poly(A)+ RNA was extracted from rat cochleae using guanidinium thiocyanate and oligo(dT)-cellulose, and converted into cDNA by reverse transcriptase using an oligo(dT) primer. …990Cite
Effect of phenylisothiocyanate on organic cation transport in opossum kidney cells.
Ott RJ, Chan JK, Ramanathan VK, Hui AC, Giacomini KM.J Pharmacol Exp Ther. 1994 Apr;269(1):204-8.PMID: 8169826991Cite
Kanazawa H, Fujimoto S, Ohara A.Biol Pharm Bull. 1994 Apr;17(4):476-81. doi: 10.1248/bpb.17.476.PMID: 8069251 Free article.
The oxidation of AsA was unaffected by catalase. Both thiourea and sodium thiocyanate completely protected the enzyme from inactivation, while AsA was partially oxidized only in the initial stage. …The present results suggest that H2O2 serves as a source of secondary, hi …992Cite
Filteau SM, Sullivan KR, Anwar US, Anwar ZR, Tomkins AM.Eur J Clin Nutr. 1994 Apr;48(4):293-302.PMID: 8039490
Other dietary factors which could potentially contribute to goitre–vitamin A or selenium deficiency or intake of large amounts of thiocyanate-producing goitrogens–were found not to be a problem among these women. Multiple regression analysis of the causes of goitre, incl …993Cite
Levin S, Tawil G.J Pharm Biomed Anal. 1994 Apr;12(4):499-507. doi: 10.1016/0731-7085(93)e0002-5.PMID: 7918766994Cite
Ogita K, Sakamoto T, Han D, Azuma Y, Yoneda Y.Neurochem Int. 1994 Apr;24(4):379-88. doi: 10.1016/0197-0186(94)90116-3.PMID: 7520311
The addition of potassium thiocyanate almost quadrupled binding of [3H]DL-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) to an AMPA-sensitive subclass of brain excitatory amino acid receptors in rat brain synaptic membranes, treated with Triton X-100. …995Cite
Cannon EP, Leung P, Hawkins A, Petrikovics I, DeLoach J, Way JL.J Toxicol Environ Health. 1994 Mar;41(3):267-74. doi: 10.1080/15287399409531842.PMID: 8126749
Prior studies indicated that these carrier erythrocytes persist in the vascular system for the same length of time as normal erythrocytes and can enhance metabolism of cyanide to thiocyanate. The present studies demonstrate the ability of these carrier red blood cells cont …996Cite
An improved T1/A ribonuclease protection assay.
Bordonaro M, Saccomanno CF, Nordstrom JL.Biotechniques. 1994 Mar;16(3):428-30.PMID: 7514423 No abstract available.997Cite
Taylor CR, Shi SR, Chaiwun B, Young L, Imam SA, Cote RJ.Hum Pathol. 1994 Mar;25(3):263-70. doi: 10.1016/0046-8177(94)90198-8.PMID: 7512074
Urea solution, distilled water, and lead thiocyanate solution yielded improvements with some antigens, but less consistently and less impressively than glycine HCl buffer or citrate buffer. …998Cite
Thomas EL, Milligan TW, Joyner RE, Jefferson MM.Infect Immun. 1994 Feb;62(2):529-35. doi: 10.1128/iai.62.2.529-535.1994.PMID: 8300211 Free PMC article.
In secreted fluids, the enzyme lactoperoxidase (LP) catalyzes the oxidation of thiocyanate ion (SCN-) by hydrogen peroxide (H2O2), producing the weak oxidizing agent hypothiocyanite (OSCN-), which has bacteriostatic activity. However, H2O2 has antibacterial activity in the …999Cite
Modderman WE, Vrijheid-Lammers T, Löwik CW, Nijweide PJ.Exp Hematol. 1994 Feb;22(2):194-201.PMID: 8299740
In contrast to fibroblastlike cells, hematopoietic cells and macrophages form under the influence of ATP4- lesions in their plasma membranes, which allows the entrance of molecules such as ethidium bromide (EB) and potassium thiocyanate (KSCN), which normally do not easily …1,000Cite
Thomas EL, Jefferson MM, Joyner RE, Cook GS, King CC.J Dent Res. 1994 Feb;73(2):544-55. doi: 10.1177/00220345940730021001.PMID: 8120219
Dissolve and capture: a strategy for analysing mRNA in blood.
Gillespie DH, Cuddy KK, Kolbe T, Marks DI.Nature. 1994 Jan 27;367(6461):390-1. doi: 10.1038/367390a0.PMID: 7509457
Messenger RNA (mRNA) sequences were amplified from whole blood prepared in guanidine thiocyanate (GuSCN) after capture of the mRNA with an affinity membrane….1,002Cite
Barnikol WK.Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):725-31. doi: 10.3109/10731199409117904.PMID: 79943941,003Cite
C-terminal sequencing of peptides. The thiocyanate degradation method.
Casagranda F, Wilshire JF.Methods Mol Biol. 1994;32:335-49. doi: 10.1385/0-89603-268-X:335.PMID: 7951734 Review. No abstract available.1,004Cite
Fluoride inhibits the antimicrobial peroxidase systems in human whole saliva.
Hannuksela S, Tenovuo J, Roger V, Lenander-Lumikari M, Ekstrand J.Caries Res. 1994;28(6):429-34. doi: 10.1159/000262016.PMID: 7850846
Furthermore, the generation of the actual antimicrobial agent in vivo, hypothiocyanite (HOSCN/OSCN-), of the oral peroxidase systems was inhibited by F-, again at low pH (5.0-5.5) both in buffer (by 45%) and in saliva (by 15%). …1,005Cite
[Expression of cytokines and interferon-related genes in the mouse embryo].
Kita M, Tanaka K, Shinmura K, Tanaka Y, Liu Y, Imanishi J.C R Seances Soc Biol Fil. 1994;188(5-6):593-600.PMID: 7540102 French.
Total RNA was prepared from the days 7 embryos by acid guanidinium thiocyanate-phenol-chloroform (AGPC) method. cDNA was synthesized by M-MLV reverse transcriptase, and amplified using the specific oligonucleotide primers for IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, TNF-alpha, …1,006Cite
Mechanisms of chemical injury of thyroid gland.
Capen CC.Prog Clin Biol Res. 1994;387:173-91.PMID: 7526405 Review.
This includes 1) inhibition of the iodine-trapping mechanism (thiocyanate or perchlorate), 2) blockage of organic binding of iodine and coupling of iodothyronines to form thyroxine (T4) and triiodothyronine (T3) (e.g., sulfonamides, thiourea, methimazole, and aminotriazole …1,007Cite
Engblom AC, Akerman KE.Biochim Biophys Acta. 1993 Dec 12;1153(2):262-6. doi: 10.1016/0005-2736(93)90414-u.PMID: 82744961,008Cite
Strauss KI, Jacobowitz DM.Brain Res Mol Brain Res. 1993 Nov;20(3):229-39. doi: 10.1016/0169-328x(93)90045-q.PMID: 8302161
Discrete nuclei and other regions of the brain are solubilized in concentrated guanidine thiocyanate solution, mRNA is directly hybridized with riboprobes, and detected with a ribonuclease protection assay. …1,009Cite
Salivary antimicrobial proteins in patients with Crohn’s disease.
Sundh B, Johansson I, Emilson CG, Nordgren S, Birkhed D.Oral Surg Oral Med Oral Pathol. 1993 Nov;76(5):564-9. doi: 10.1016/0030-4220(93)90063-a.PMID: 8247499
Unstimulated saliva was analyzed for concentrations of total protein, peroxidase, thiocyanate, slgA, lactoferrin, lysozyme, and for specific bacteria aggregation ability. …No differences were found among the groups regarding salivary flow rate, total protein, or any of t …1,010Cite
Detection of human rhinovirus RNA in nasal washings by PCR.
Arruda E, Hayden FG.Mol Cell Probes. 1993 Oct;7(5):373-9. doi: 10.1006/mcpr.1993.1055.PMID: 8264671
Total RNA was purified from samples stored in the presence of vanadyl ribonucleoside complex (VRC) by one of two methods: proteinase K digestion followed by multiple extractions with phenol/chloroform (PK-PC); or denaturation with guanidinium thiocyanate followed by one ph …1,011Cite
Chomczynski P.Biotechniques. 1993 Sep;15(3):532-4, 536-7.PMID: 7692896
The method is based on the use of a reagent containing phenol and guanidine thiocyanate. A biological sample is homogenized in the reagent and the simultaneous isolation of RNA, DNA and proteins is accomplished in a single step by a liquid-phase separation. …1,012Cite
Silver acetate mouth spray as an aid in smoking cessation: results of a double-blind trial.
Morrow R, Nepps P, McIntosh M.J Am Board Fam Pract. 1993 Jul-Aug;6(4):353-7.PMID: 8352038 Clinical Trial.
The spray was to be used every 2 hours for 3 weeks during which time the subjects were to keep diaries of cigarette smoking and spray use. Biochemical measures (salivary thiocyanate and cotinine) were recorded at entry, at 3 weeks, and at 3 months. RESULTS: Thirty smokers …1,013Cite
Bowie D, Smart TG.Br J Pharmacol. 1993 Jul;109(3):779-87. doi: 10.1111/j.1476-5381.1993.tb13642.x.PMID: 7689403 Free PMC article.
1 Responses to kainate (KA), willardiine and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) were recorded from rat brain mRNA-injected Xenopus laevis oocytes by use of a two-electrode voltage clamp. 2 Thiocyanate (SCN-; 50 microM-4 mM) ions reversibly and …1,014Cite
Simple method for extracting RNA from cultured cells and tissue with guanidine salts.
Zolfaghari R, Chen X, Fisher EA.Clin Chem. 1993 Jul;39(7):1408-11.PMID: 7687204
We have developed a simple protocol for isolating RNA from both cell culture and tissue from human and animal sources, using guanidine thiocyanate and guanidine hydrochloride, but no organic solvents. The protocol reproducibly yielded 15 to 25 micrograms of high-quality RN …1,015Cite
Chungue E, Roche C, Lefevre MF, Barbazan P, Chanteau S.J Med Virol. 1993 Jun;40(2):142-5. doi: 10.1002/jmv.1890400211.PMID: 7689635
Recovery of RNA is based on the lysing and nuclease-inactivating properties of guanidinium thiocyanate in the presence of silica. The silica RT-PCR can be completed within 5 hours starting from RNA extraction to agarose gel electrophoresis. …1,016Cite
Detection of HIV-1 in serum, using reverse transcription and the polymerase chain reaction (RT-PCR).
Gibson KM, Mori J, Clewley JP.J Virol Methods. 1993 Jun;43(1):101-9. doi: 10.1016/0166-0934(93)90093-7.PMID: 7689579
Viral RNA present in serum is bound to silica particles in the presence of a high concentration of guanidinium thiocyanate (GuSCN) which denatures any proteins present, specifically ribonucleases. After washing the RNA/silica pellet, the RNA is eluted in water and reverse …1,017Cite
Rudney JD, Krig MA, Neuvar EK.Arch Oral Biol. 1993 May;38(5):377-86. doi: 10.1016/0003-9969(93)90208-4.PMID: 8392324
Many studies have attempted to relate levels of antimicrobial proteins in saliva to oral health; results have been inconsistent, and one reason might be inconsistency of measures of plaque and saliva within subjects. …They also support previous cross-sectional data which …1,018Cite
Nicolli A, Petronilli V, Bernardi P.Biochemistry. 1993 Apr 27;32(16):4461-5. doi: 10.1021/bi00067a039.PMID: 7682848
This hypothesis was confirmed in studies with deenergized mitochondria incubated in potassium thiocyanate medium. While at acidic pH values pore opening is otherwise prevented, DPC allows Ca2(+)-dependent pore opening at pH 6.5 in a process that maintains full sensitivity …1,019Cite
Supawan V, Tungtrongchitr R, Prayurahong B, Pongpaew P, Sanchaisuriya P, Kassomboon P, Saowakontha S, Schelp FP, Migasena P.J Med Assoc Thai. 1993 Apr;76(4):210-6.PMID: 8113641
Further study about the determination of thiocyanate should be suggested in the high prevalence of goiter….1,020Cite
Jalil RA, Ashley FP, Wilson RF, Wagaiyu EG.J Periodontal Res. 1993 Mar;28(2):130-6. doi: 10.1111/j.1600-0765.1993.tb01060.x.PMID: 8478785
Resting and stimulated whole saliva was collected from 94 children aged 12-14 years and analyzed for thiocyanate, hypothiocyanite, ‘free’ and ‘total’ lysozyme, lactoferrin and secretory IgA. …An inverse relationship was observed between salivary thiocyanate concen …1,021Cite
Finke J, Fritzen R, Ternes P, Lange W, Dölken G.Biotechniques. 1993 Mar;14(3):448-53.PMID: 7681300
We describe a procedure for RNA extraction from different types of FFPE tissues, involving digestion with proteinase K followed by guanidinium-thiocyanate acid phenol extraction and DNase I digestion. These RNA preparations are suitable for PCR analysis of mRNA and even of …1,022Cite
A simple method for isolation of DNA from blood clots suited for use in PCR.
Zeillinger R, Schneeberger C, Speiser P, Kury F.Biotechniques. 1993 Feb;14(2):202-3.PMID: 8431280
Our method is based on the lysing and nuclease-inactivating properties of guanidine thiocyanate together with the nucleic acid-binding properties of silica particles. Isolated DNA can be used for in vitro amplification as shown for a retinoblastoma gene PCR system….1,023Cite
Thilly CH, Swennen B, Bourdoux P, Ntambue K, Moreno-Reyes R, Gillies J, Vanderpas JB.Am J Clin Nutr. 1993 Feb;57(2 Suppl):267S-270S. doi: 10.1093/ajcn/57.2.267S.PMID: 8427202
In children aged 5-7 y from goiter-endemic areas in Ubangi, Zaire, and Ntcheu, Malawi, mean serum thyroxin (T4) concentrations were 53 +/- 49 vs 81 +/- 33 nmol/L (P < 0.05), and thyroid-stimulating hormone (TSH) values were 24.3 +/- 9.6 vs 4.5 +/- 3.3 mU/L respectively (P <…1,024Cite
A rapid and sensitive in vitro assay for the activity of Bacillus thuringiensis delta-endotoxins.
Parenti P, Villa M, Tasca M, Belgiojoso P, Hanozet GM, Giordana B.Comp Biochem Physiol B. 1993 Feb;104(2):375-9. doi: 10.1016/0305-0491(93)90382-f.PMID: 83849641,025Cite
Electroretinographic assessment of early retinopathy in rats.
Maertins T, Kroetlinger F, Sander E, Pauluhn J, Machemer L.Arch Toxicol. 1993;67(2):120-5. doi: 10.1007/BF01973682.PMID: 84811001,026Cite
van der Hoeven JS, Camp PJ.Caries Res. 1993;27(1):26-30. doi: 10.1159/000261511.PMID: 8448770
However, the concentrations of hydrogen peroxide (30 mumol/l in the mixed culture of S. mutans with S. sanguis and 640 mumol/l in the culture with S. oralis) indicated a certain resistance of the organisms to hydrogen peroxide. Addition of lactoperoxidase and thiocyanate t …1,027Cite
Endemic juvenile hypothyroidism in a severe endemic goitre area of Sudan.
Moreno-Reyes R, Boelaert M, el Badawi S, Eltom M, Vanderpas JB.Clin Endocrinol (Oxf). 1993 Jan;38(1):19-24. doi: 10.1111/j.1365-2265.1993.tb00967.x.PMID: 8435881
MEASUREMENTS: Thyroid hormones, urinary iodide and thiocyanate excretion were measured. RESULTS: Mean +/- SD serum T4 was below the normal range at birth (82 +/- 50 nmol/l) and in the age group less than 2 years (73 +/- 46). …The higher frequency of hypothyroidism observ …1,028Cite
A new hypothesis: iodine and gastric cancer.
Venturi S, Venturi A, Cimini D, Arduini C, Venturi M, Guidi A.Eur J Cancer Prev. 1993 Jan;2(1):17-23.PMID: 8428171
This ability is impaired by nitrates, thiocyanate, salt and by I-excess, which in fact can cause goitre. In our study I-def goitrous people have shown more atrophic gastritis than normal subjects. These data enable us to hypothesize that I-def or I-excess might constitute …1,029Cite
Lenander-Lumikari M, Tenovuo J, Mikola H.Caries Res. 1993;27(4):285-91. doi: 10.1159/000261552.PMID: 8402803 Clinical Trial.
The salivary counts of total streptococci, mutans streptococci (MS), lactobacilli and the total flora (TF), as well as the peroxidase, thiocyanate ion and HOSCN/OSCN- levels were determined before and after 2 and 4 weeks daily use of the toothpastes. …1,030Cite
Ngogang J, Meli J, Carteret P.Ann Endocrinol (Paris). 1993;54(3):191-6.PMID: 8024245 French.1,031Cite
Effects of glucosinolate breakdown products on the hepatic biotransformation system in male rats.
Ozierenski B, Plass R, Lewerenz HJ.Nahrung. 1993;37(1):5-14. doi: 10.1002/food.19930370103.PMID: 76819351,032Cite
Kataoka K, Mitani A, Andou Y, Enomoto R, Ogita K, Yoneda Y.Neurochem Int. 1993 Jan;22(1):37-43. doi: 10.1016/0197-0186(93)90066-e.PMID: 76802601,033Cite
[Induction of messenger RNA of cytokines by Herpes simplex virus infection in mice].
Kita M, Tong LJ, Imanishi J.C R Seances Soc Biol Fil. 1993;187(4):561-8.PMID: 7517338 French.
Total RNA was prepared from spleen lymphocytes 3 h after infection with HSV-1 (+GC virulent variant and -GCr attenuated variant of Miyama strain) by acid guanidinium thiocyanate-phenol-chloroform (AGPC) method. cDNA was synthesized by M-MLV reverse transcriptase, and ampli …1,034Cite
Mechanism of differential inhibition of lactate dehydrogenase isoenzymes in the BMC LD-1 assay.
Onigbinde TA, Wu AH, Wu YS, Simmons MJ, Wong SS.Clin Biochem. 1992 Dec;25(6):425-9. doi: 10.1016/0009-9120(92)90045-t.PMID: 1477966
The mechanism of inhibition of lactate dehydrogenase (LD) isoenzymes by guanidinium thiocyanate (GSCN) used in the LD-1 assay developed by Boehringer Mannheim Corporation (BMC) was investigated. …Separate experiments demonstrated that both guanidinium and thiocyanate …1,035Cite
van den Abbeele A, Pourtois M, Courtois P.J Biol Buccale. 1992 Dec;20(4):219-24.PMID: 1339090
Fluoride (F-) inhibition of peroxidase activity in whole saliva and of recombinant human myeloperoxidase was investigated using thiocyanate (SCN-) and chloride (Cl-) as substrates. At pH 5.5, SCN(-)-linked activity in whole saliva reduced to < 40% of its initial value a…1,036Cite
Majerus PM, Courtois PA.J Biol Buccale. 1992 Dec;20(4):241-5.PMID: 1306188
The survival rate of Candida blastospores after a 30 min exposure to lactoperoxidase system ranged from 79 to 105% in the presence of 615 microM thiocyanate, from 56 to 88% in the presence of 345 microM bromide and from 0 to 4% in the presence of 250 microM iodide. …Neve …1,037Cite
Fukayama H, Nasu M, Murakami S, Sugawara M.Acta Endocrinol (Copenh). 1992 Dec;127(6):520-5. doi: 10.1530/acta.0.1270520.PMID: 1283478
When 50 mumol/l thiocyanate was added 2 h after incubation with iodide or when 1 mumol/l thiocyanate was added from the beginning of incubation, iodine organification was inhibited without changing iodide transport. De novo thyroid hormone formation was clearly inhi …1,038Cite
A simplified ribonuclease protection assay.
Hod Y.Biotechniques. 1992 Dec;13(6):852-4.PMID: 1282345 No abstract available.1,039Cite
A faster ribonuclease protection assay.
Saccomanno CF, Bordonaro M, Chen JS, Nordstrom JL.Biotechniques. 1992 Dec;13(6):846-50.PMID: 1282344 No abstract available.1,040Cite
Purification of cloned and genomic DNA by guanidine thiocyanate/isobutyl alcohol fractionation.
Nelson JE, Krawetz SA.Anal Biochem. 1992 Nov 15;207(1):197-201. doi: 10.1016/0003-2697(92)90523-a.PMID: 1489096
We have developed a rapid and efficient method to purify cloned or high molecular weight eukaryotic DNA from cell lysates using guanidine thiocyanate and isobutyl alcohol. This simple two-step extraction procedure utilizes isobutyl alcohol to fractionate DNA away from cell …1,041Cite
Alonso-Torre SR, Serrano MA, Medina JM, Alvarado F.Biochem J. 1992 Nov 15;288 ( Pt 1)(Pt 1):47-53. doi: 10.1042/bj2880047.PMID: 1445280 Free PMC article.
When Na+ is present, S-1, but not S-2, appears to be rheogenic, since its maximal transport capacity significantly increases in the presence of an inside-negative membrane potential, created either by replacing Cl- with the permeant anion thiocyanate (NaSCN > NaCl) or b …1,042Cite
Inhibition of Candida albicans by the Peroxidase/SCN-/H2O2 system.
Lenander-Lumikari M.Oral Microbiol Immunol. 1992 Oct;7(5):315-20. doi: 10.1111/j.1399-302x.1992.tb00595.x.PMID: 14944571,043Cite
Susceptibility of anaerobic microorganisms to hypothiocyanite produced by lactoperoxidase.
Courtois P, Majerus P, Labbé M, Vanden Abbeele A, Yourassowsky E, Pourtois M.Acta Stomatol Belg. 1992 Sep;89(3):155-62.PMID: 14817641,044Cite
Methyl isothiocyanate in wine.
Rostron C.Food Chem Toxicol. 1992 Sep;30(9):821-3. doi: 10.1016/0278-6915(92)90089-4.PMID: 1427521 Review. No abstract available.1,045Cite
Free radical generation and coupled thiol oxidation by lactoperoxidase/SCN-/H2O2.
Løvaas E.Free Radic Biol Med. 1992 Sep;13(3):187-95. doi: 10.1016/0891-5849(92)90014-8.PMID: 1324202
The lactoperoxidase-catalyzed oxidation of glutathione (GSH) and thiocyanate (SCN-) was studied. Oxidation of SCN- was recorded by ultraviolet spectroscopy and by electron spin resonance (ESR). …1,046Cite
Hall VA, Guest JM.Am J Crit Care. 1992 Sep;1(2):19-25; quiz 26-7.PMID: 1307887 Review.
Cyanide combines with thiosulfate to form the less toxic sodium thiocyanate, which is then excreted. A 10:1 ratio of nitroprusside to thiosulfate in the infusion eliminates the possibility of cyanide intoxication without altering the efficacy of nitroprusside….1,047Cite
Lactoferrin-binding proteins in Shigella flexneri.
Tigyi Z, Kishore AR, Maeland JA, Forsgren A, Naidu AS.Infect Immun. 1992 Jul;60(7):2619-26. doi: 10.1128/iai.60.7.2619-2626.1992.PMID: 1319403 Free PMC article.1,048Cite
Tenovuo J, Jentsch H, Soukka T, Karhuvaara L.J Biol Buccale. 1992 Jun;20(2):85-90.PMID: 1644785
The possible association between salivary non-immunoglobulin (lysozyme, lactoferrin, hypothiocyanite, agglutinins) or immunoglobulin (total IgA, anti-Streptococcus mutans IgA) antimicrobial factors, and the prevalence of dental caries was studied in 59 young adults. These …1,049Cite
Smale G, Sasse J.Anal Biochem. 1992 Jun;203(2):352-6. doi: 10.1016/0003-2697(92)90324-z.PMID: 1384388
The difficulties in obtaining RNA from cartilage, a tissue of low cell density and high proteoglycan content, were overcome by making several modifications to the guanidine thiocyanate/cesium chloride method of RNA extraction. Cartilage tissue is frozen, crushed, and homog …1,050Cite
Persistence of eggs and hepatic fibrosis after treatment of Schistosoma mansoni-infected mice.
Cheever AW, Macedonia JG, Deb S, Cheever EA, Mosimann JE.Am J Trop Med Hyg. 1992 Jun;46(6):752-8. doi: 10.4269/ajtmh.1992.46.752.PMID: 1320344 Free article.1,051Cite
Lethal oxidative damage to human immunodeficiency virus by human recombinant myeloperoxidase.
Moguilevsky N, Steens M, Thiriart C, Prieels JP, Thiry L, Bollen A.FEBS Lett. 1992 May 18;302(3):209-12. doi: 10.1016/0014-5793(92)80442-j.PMID: 1318224 Free article.
In the presence of a hydrogen peroxide generating system (glucose and glucose oxidase) and sodium thiocyanate, the recombinant enzyme inhibited virus-induced syncytium formation and viral replication without causing any cytopathic effects on SupT1 reporter cells. …1,052Cite
Synthesis and biological activity of some heterocyclic systems containing anthraquinone.
Berghot MA, Hanna MA, Girges MM.Pharmazie. 1992 May;47(5):340-3.PMID: 1409825
Compound 8 was treated with potassium thiocyanate to give 12, which was cyclized to 13a, while the reaction between 8 and potassium cyanate gave 13b directly. …1,053Cite
RNA abundance measured by a lysate RNase protection assay.
Haines DS, Gillespie DH.Biotechniques. 1992 May;12(5):736-41.PMID: 1381196
Cell lysates were prepared in concentrated guanidine thiocyanate. Molecular hybridization with RNA probes was then performed directly in crude cell lysate, and native RNase-resistant duplexes were characterized by polyacrylamide gel electrophoresis. …1,054Cite
Regulation of glycine catabolism in rat liver mitochondria.
Jois M, Ewart HS, Brosnan JT.Biochem J. 1992 Apr 15;283 ( Pt 2)(Pt 2):435-9. doi: 10.1042/bj2830435.PMID: 1575688 Free PMC article.
This requirement for phosphate was specific, as replacement of phosphate by other permeant anions such as thiocyanate and acetate did not permit the stimulation. The phosphate-dependent stimulation of glycine catabolism by Ca2+ was also evident when mitochondria were incub …1,055Cite
Lenander-Lumikari M, Månsson-Rahemtulla B, Rahemtulla F.J Dent Res. 1992 Mar;71(3):484-90. doi: 10.1177/00220345920710031201.PMID: 15730811,056Cite
Investigation of anion binding to neutral lipid membranes using 2H NMR.
Rydall JR, Macdonald PM.Biochemistry. 1992 Feb 4;31(4):1092-9. doi: 10.1021/bi00119a018.PMID: 1734958
Calibration of the 2H NMR quadrupole splittings with the amount of membrane-bound anion permitted binding isotherms to be generated for perchlorate, thiocyanate, and iodide, up to concentrations of 100 mM. The binding isotherms were analyzed by considering electrostatic co …1,057Cite
Dionysius DA, Grieve PA, Vos AC.J Appl Bacteriol. 1992 Feb;72(2):146-53. doi: 10.1111/j.1365-2672.1992.tb01816.x.PMID: 1556038
Components of the lactoperoxidase system were measured during incubation in Isosensitest broth, with enzymatic (glucose oxidase, GO) or chemical (sodium carbonate peroxyhydrate, SCP) means to generate H2O2. When low levels of thiocyanate (SCN-) were used in the GO system, …1,058Cite
Evaluation of sodium thiosulfate as an extracellular water marker in cattle.
Ross JG, Preston RL, Bartle SJ.J Anim Sci. 1992 Feb;70(2):434-8. doi: 10.2527/1992.702434x.PMID: 1548205
Experiment 2 consisted of 22 steers (483 kg) infused with a combination solution of 20% urea, 10% THS, and 4% sodium thiocyanate (SCN; equilibration time = 28 min); half the steers were implanted with estradiol. …1,059Cite
Gras C, Hellec C, Spiegel A, Chungue E, Boutin JP, Cardines R, Laudon F, Legall R, Roy C, Prigent D, et al.Med Trop (Mars). 1992 Jan-Mar;52(1):57-61.PMID: 1602954 French.1,060Cite
Jalil RA, Ashley FP, Wilson RF.Arch Oral Biol. 1992 Jan;37(1):23-8. doi: 10.1016/0003-9969(92)90148-2.PMID: 15962051,061Cite
Analyses of salivary components in leukemia patients receiving chemotherapy.
Månsson-Rahemtulla B, Techanitiswad T, Rahemtulla F, McMillan TO, Bradley EL, Wahlin YB.Oral Surg Oral Med Oral Pathol. 1992 Jan;73(1):35-46. doi: 10.1016/0030-4220(92)90151-f.PMID: 1376467
At the time of diagnosis no significant differences in thiocyanate (SCN-) concentrations were found in saliva samples from control subjects and patients with leukemia. Treatment with cytotoxic agents resulted in granulocytopenia and a concomitant decrease in the SCN …1,062Cite
Thilly CH, Vanderpas JB, Bebe N, Ntambue K, Contempre B, Swennen B, Moreno-Reyes R, Bourdoux P, Delange F.Biol Trace Elem Res. 1992 Jan-Mar;32:229-43. doi: 10.1007/BF02784606.PMID: 1375059 Clinical Trial.
Apart from the degrees of severity of the iodine deficiency, the frequencies and symptomatologies of cretinism and the other IDD are influenced by other goitrogenic factors and trace elements. Thiocyanate overload originating from consumption of poorly detoxified cassava i …1,063Cite
el-Shahat MF, Abdel Badei MM, Daifullah AA.J Chem Technol Biotechnol. 1992;54(2):175-81. doi: 10.1002/jctb.280540212.PMID: 13682721,064Cite
Problems of iodine and thiocyanate in domestic animals in goitrogenic areas of southern Poland.
Bobek S, Ewy Z, Kahl S, Pyska H.Endokrynol Pol. 1992;43 Suppl 1:70-82.PMID: 1345587
A low correlation coefficient suggest that iodine is not a solely factor responsible for goitre development. Studies on cows have indicated that thiocyanate may have effect on goitre development as well. There has been found higher concentration of thiocyanate (SCN) …1,065Cite
Lenander-Lumikari M, Tenovuo J, Emilson CG, Vilja P.Caries Res. 1992;26(5):371-8. doi: 10.1159/000261471.PMID: 1334804
We have studied the possible relationship between indigenous salivary antimicrobial agents, indigenous mutans streptococci and the capability of added mutans streptococci to grow in saliva. …Saliva samples were analysed, both before and after sterilization, for in …1,066Cite
Prevention by chemopreventive agents of azoxymethane-induced foci of aberrant crypts in rat colon.
Pereira MA, Khoury MD.Cancer Lett. 1991 Dec 9;61(1):27-33. doi: 10.1016/0304-3835(91)90073-q.PMID: 1837244
The animals started to receive the test agents in their diet 1 week prior to the first injection of azoxymethane and continuously until killed 5 weeks later. …Our results suggest that four of the tested agents might reduce azoxymethane-induced colon cancer, which …1,067Cite
McKinley MP, Taraboulos A, Kenaga L, Serban D, Stieber A, DeArmond SJ, Prusiner SB, Gonatas N.Lab Invest. 1991 Dec;65(6):622-30.PMID: 1684401
To determine the subcellular localization of PrPSc, scrapie-infected cells were grown to approximately 75% confluency, fixed briefly, and then incubated with guanidine thiocyanate before antibody staining and examination by electron microscopy. PrPSc immunoreactivity was e …1,068Cite
Voltage-dependent phosphate transport in osteoblast-like cells.
Luong KV, Green J, Kleeman CR, Yamaguchi DT.J Bone Miner Res. 1991 Nov;6(11):1161-5. doi: 10.1002/jbmr.5650061104.PMID: 18055401,069Cite
Modi S, Behere DV, Mitra S.Biochim Biophys Acta. 1991 Oct 11;1080(1):45-50. doi: 10.1016/0167-4838(91)90110-l.PMID: 1932081
Horseradish peroxidase-catalysed oxidation of thiocyanate by hydrogen peroxide has been studied by 15N-NMR and optical spectroscopy at different concentrations of thiocyanate and hydrogen peroxide and at different pH values. …Chem. 264, 19677-19684), the binding o …1,070Cite
Park CS, Honeyman TW, Ha SK, Choi HK, Chung CL, Hong CD.J Pharmacol Exp Ther. 1991 Oct;259(1):211-8.PMID: 1920117
The extent of stimulation by the two ionophores was dependent upon the presence of anion with acetate greater than Cl greater than isethionate greater than thiocyanate. Thiocyanate itself markedly inhibited renin secretion. Incubating of slices in an iso-osmotic amm …1,071Cite
Soukka T, Lumikari M, Tenovuo J.Scand J Dent Res. 1991 Oct;99(5):390-6. doi: 10.1111/j.1600-0722.1991.tb01046.x.PMID: 1754841
Apo LF enhanced the LP enzyme activity but decreased the yield of the antimicrobial component, hypothiocyanite (HOSCN/OSCN-), when incorporated into the reaction mixtures. …1,072Cite
Effects of nitroscanate on adult Taenia pisiformis in dogs with experimentally induced infections.
Bowman DD, Lin DS, Johnson RC, Lynn RC, Hepler DI, Stansfield DG.Am J Vet Res. 1991 Sep;52(9):1542-4.PMID: 18353261,073Cite
Cold denaturation and 2H2O stabilization of a staphylococcal nuclease mutant.
Antonino LC, Kautz RA, Nakano T, Fox RO, Fink AL.Proc Natl Acad Sci U S A. 1991 Sep 1;88(17):7715-8. doi: 10.1073/pnas.88.17.7715.PMID: 1652762 Free PMC article.1,074Cite
Kominami E, Ueno T, Muno D, Katunuma N.FEBS Lett. 1991 Aug 5;287(1-2):189-92. doi: 10.1016/0014-5793(91)80048-8.PMID: 1715285 Free article.1,075Cite
Severe iodine deficiency in two endemic goitre areas of Zimbabwe.
Todd CH, Bourdeux PP.Cent Afr J Med. 1991 Aug;37(8):237-41.PMID: 1807795
The purpose of the study was to investigate the iodine status of the population and the possible role of goitregens (that are metabolised to thiocyanate), in two endemic goitre areas of Zimbabwe. This was done through estimation of iodine (I) and thiocyanate (SCN) l …1,076Cite
van Iwaarden JF, van Strijp JA, Ebskamp MJ, Welmers AC, Verhoef J, van Golde LM.Am J Physiol. 1991 Aug;261(2 Pt 1):L204-9. doi: 10.1152/ajplung.1991.261.2.L204.PMID: 16516681,077Cite
Lawrence JF, Ménard C.J Chromatogr. 1991 Jul 26;550(1-2):595-601. doi: 10.1016/s0021-9673(01)88565-4.PMID: 17742311,078Cite
Wirth HJ, Unger KK, Hearn MT.J Chromatogr. 1991 Jul 26;550(1-2):383-95. doi: 10.1016/s0021-9673(01)88551-4.PMID: 1663504
The elution was performed in each case with a 2.5 M potassium thiocyanate solution. With the porous silica dye sorbents and 1 M NaCl present in the loading buffer, the highest capacity was achieved when Cibacron Blue F3GA was immobilised to the level of 0.1 mumol/m2. …1,079Cite
A method for the analysis of newly synthesized tritiated mRNA.
Ayoubi TA, de Kleijn DP, Roubos EW, Martens GJ.Nucleic Acids Res. 1991 Jul 11;19(13):3751. doi: 10.1093/nar/19.13.3751.PMID: 1852618 Free PMC article.1,080Cite
Hueso-Ureña F, Moreno-Carretero MN, Salas-Peregrín JM, Alvarez de Cienfuegos-López G.J Inorg Biochem. 1991 Jul;43(1):17-27. doi: 10.1016/0162-0134(91)84065-h.PMID: 1940899
Seven complexes containing neutral isoorotic and 2-thioisoorotic acids, as well as thiocyanate and chloride anions as lignands, have been synthesized and characterized by means of both spectral (IR, 1H, and 13C NMR) and thermal (TG and DSC) methods, as well as conductivity …1,081Cite
Snider DP, Uppenkamp IK, Titus JA, Segal DM.Mol Immunol. 1991 Jul;28(7):779-88. doi: 10.1016/0161-5890(91)90121-y.PMID: 19069831,082Cite
Klebanoff SJ, Coombs RW.J Exp Med. 1991 Jul 1;174(1):289-92. doi: 10.1084/jem.174.1.289.PMID: 1647436 Free PMC article.
Peroxidase, H2O2, and a halide form a powerful antimicrobial system in phagocytes and tissue fluids, and certain microorganisms can serve as the source of H2O2 for this system. …LB+ at high concentration is viricidal to HIV-1, and, at levels where LB+ is ineffective alon …1,083Cite
Control of the microbial flora of the vagina by H2O2-generating lactobacilli.
Klebanoff SJ, Hillier SL, Eschenbach DA, Waltersdorph AM.J Infect Dis. 1991 Jul;164(1):94-100. doi: 10.1093/infdis/164.1.94.PMID: 1647428
LB+ could be replaced by H2O2 and chloride by iodide, bromide, or thiocyanate. The optimum pH for inhibition of G. vaginalis was 5.0-6.0 LB+ also was autoinhibitory when combined with myeloperoxidase and chloride. …1,084Cite
The synthesis of polyphenylalanine on ribosomes to which erythromycin is bound.
Odom OW, Picking WD, Tsalkova T, Hardesty B.Eur J Biochem. 1991 Jun 15;198(3):713-22. doi: 10.1111/j.1432-1033.1991.tb16071.x.PMID: 1904819 Free article.1,085Cite
Legrand D, Mazurier J, Maes P, Rochard E, Montreuil J, Spik G.Biochem J. 1991 Jun 15;276 ( Pt 3)(Pt 3):733-8. doi: 10.1042/bj2760733.PMID: 1648350 Free PMC article.1,086Cite
Lumikari M, Tenovuo J.Acta Odontol Scand. 1991 Jun;49(3):175-81. doi: 10.3109/00016359109005904.PMID: 1882653
Effects of human lysozyme (HLZ) combined with thiocyanate (SCN-) ions on mutans streptococci, both in physiologic salivary concentrations, were studied. …HLZ also effectively blocked the lactic acid production of S. rattus but not that of S. mutans. Thiocyanate io …1,087Cite
Severe cyanide poisoning from the ingestion of an acetonitrile-containing cosmetic.
Turchen SG, Manoguerra AS, Whitney C.Am J Emerg Med. 1991 May;9(3):264-7. doi: 10.1016/0735-6757(91)90092-x.PMID: 2018600
The patient developed hypernatremia from the sodium load given to her; hemodialysis and charcoal hemoperfusion were initiated to correct the hypernatremia and to attempt to remove cyanide, thiocyanate, and acetonitrile. On the fifth hospital day, the patient was fully reco …1,088Cite
Biassoni P, Ravera G, Schenone F, Green J, Bertocchi J.Thyroidology. 1991 May;3(2):63-8.PMID: 1726902
Circulating TSH, TT3, TT4, FT4, rT3 and TG were determined in an accurately randomized population sample. Urinary excretion of iodine and thiocyanate (SCN) was also measured. The comparison of the mean values of such parameters with control values showed statistically sign …1,089Cite
Fisher JA, Favreau MB.Anal Biochem. 1991 May 1;194(2):309-15. doi: 10.1016/0003-2697(91)90234-k.PMID: 1713749
The protocol is based on the finding that phenol extraction of a 1 M guanidinium thiocyanate solution at pH 4.5 efficiently removes genomic DNA from the aqueous phase, while supercoiled plasmid DNA is retained in the aqueous phase. …1,090Cite
Mapping nonisotopically labeled DNA probes to human chromosome bands by confocal microscopy.
Albertson DG, Sherrington P, Vaudin M.Genomics. 1991 May;10(1):143-50. doi: 10.1016/0888-7543(91)90494-y.PMID: 17105971,091Cite
Saliva can contribute in quick inhibition of HIV infectivity.
Pourtois M, Binet C, Van Tieghem N, Courtois PR, Vandenabbeele A, Thirty L.AIDS. 1991 May;5(5):598-600.PMID: 1650564 No abstract available.1,092Cite
Hopkins TJ.Vet Rec. 1991 Apr 6;128(14):331. doi: 10.1136/vr.128.14.331.PMID: 2063526 Clinical Trial. No abstract available.1,093Cite
Craig TM, Mercer SH, Wade CG, Lynn RC.Am J Vet Res. 1991 Apr;52(4):574-5.PMID: 20537261,094Cite
Castellani-Ceresa L, Brivio MF, Radaelli G.J Submicrosc Cytol Pathol. 1991 Apr;23(2):347-9.PMID: 19063731,095Cite
Leung P, Davis RW, Yao CC, Cannon EP, Way JL.Fundam Appl Toxicol. 1991 Apr;16(3):559-66. doi: 10.1016/0272-0590(91)90095-l.PMID: 1855626
Prior studies indicated that erythrocytes containing encapsulated rhodanese and sodium thiosulfate metabolized cyanide to thiocyanate in vitro. Studies were conducted to investigate the properties of these sulfurtransferase-loaded red blood cells in vivo by administering t …1,096Cite
Weingartl HM, Derbyshire JB.Can J Vet Res. 1991 Apr;55(2):143-9.PMID: 1653103 Free PMC article.
Porcine interferon (POIFN)-alpha prepared in primed peripheral blood leukocyte cultures induced with Newcastle disease virus and POIFN-beta from PK-15 cell cultures induced with polyinosinic:polycytidylic acid were partially purified by precipitation with potassium thiocyanate …1,097Cite
Wang YX, Shi LB, Verkman AS.Biochemistry. 1991 Mar 19;30(11):2888-94. doi: 10.1021/bi00225a023.PMID: 19010211,098Cite
Adelstein S, Pritchard-Briscoe H, Anderson TA, Crosbie J, Gammon G, Loblay RH, Basten A, Goodnow CC.Science. 1991 Mar 8;251(4998):1223-5. doi: 10.1126/science.1900950.PMID: 19009501,099Cite
Kruft V, Kapp U, Wittmann-Liebold B.Anal Biochem. 1991 Mar 2;193(2):306-9. doi: 10.1016/0003-2697(91)90026-p.PMID: 18724751,100Cite
Shimazaki KA, Nishio N.J Dairy Sci. 1991 Feb;74(2):404-8. doi: 10.3168/jds.s0022-0302(91)78182-4.PMID: 2045547
Lactoferrin, adsorbed on the dye column, could not be eluted by 8 M urea, 1% Triton X-100, and 75% ethylene glycol, but was eluted by .1 M sodium hydroxide, 1 M potassium thiocyanate, 3 M potassium chloride, and free Cibacron blue F3GA. Electrostatic forces between the sul …1,101Cite
Isotachophoresis as an on-line concentration pretreatment technique in capillary electrophoresis.
Stegehuis DS, Irth H, Tjaden UR, Van der Greef J.J Chromatogr. 1991 Feb 1;538(2):393-402. doi: 10.1016/s0021-9673(01)88860-9.PMID: 19018701,102Cite
A novel non-enzymatic procedure for removing DNA template from RNA transcription mixtures.
Kedzierski W, Porter JC.Biotechniques. 1991 Feb;10(2):210-4.PMID: 1711872
The method avoids the use of DNase and involves extraction of the RNA transcription products at acid pH using either phenol or phenol: chloroform:guanidinium thiocyanate mixture. Both procedures are as effective as DNase digestion in removing DNA template, but are free of …1,103Cite
Liposome-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells.
Harding CV, Collins DS, Slot JW, Geuze HJ, Unanue ER.Cell. 1991 Jan 25;64(2):393-401. doi: 10.1016/0092-8674(91)90647-h.PMID: 18990491,104Cite
Modi S, Deodhar SS, Behere DV, Mitra S.Biochemistry. 1991 Jan 8;30(1):118-24. doi: 10.1021/bi00215a018.PMID: 1988011
To establish the agent(s) responsible for the activity of the lactoperoxidase (LPO)/SCN-/H2O2 system, the oxidation of thiocyanate with hydrogen peroxide, catalyzed by lactoperoxidase, has been studied by 15N NMR and optical spectroscopy at different concentrations of t …1,105Cite
Elguindi S, O’Brien PJ.Adv Exp Med Biol. 1991;283:271-4. doi: 10.1007/978-1-4684-5877-0_30.PMID: 2068995 No abstract available.1,106Cite
Smoking during pregnancy: a significant cause of neonatal thyroid enlargement.
Chanoine JP, Toppet V, Bourdoux P, Spehl M, Delange F.Br J Obstet Gynaecol. 1991 Jan;98(1):65-8. doi: 10.1111/j.1471-0528.1991.tb10313.x.PMID: 1998635
There was a positive correlation (P less than 0.001) between cord serum thiocyanate (SCN) concentrations used as an index of maternal smoking and the maternal smoking habits. …1,107Cite
Lumikari M, Soukka T, Nurmio S, Tenovuo J.Arch Oral Biol. 1991;36(2):155-60. doi: 10.1016/0003-9969(91)90078-9.PMID: 1905532
Components of the antibacterial peroxidase system–hypothiocyanous acid (HOSCN) and hypothiocyanite ions (OSCN-)–were generated by adding exogenous H2O2 to sterilized saliva containing endogenous peroxidases and thiocyanate (SCN-) ions. HOSCN/OSCN- generation was proporti …1,108Cite
Engelhard HH 3rd, Krupka JL, Bauer KD.Cytometry. 1991;12(1):68-76. doi: 10.1002/cyto.990120110.PMID: 1900228 Free article.1,109Cite
Relationships between the chemical structure and cytotoxicity of 4-alkylmorpholine N-oxides.
Miko M, Devínsky F.Drug Metabol Drug Interact. 1991;9(3-4):333-51. doi: 10.1515/dmdi.1991.9.3-4.333.PMID: 18240861,110Cite
Rudney JD, Krig MA, Neuvar EK, Soberay AH, Iverson L.Arch Oral Biol. 1991;36(7):497-506. doi: 10.1016/0003-9969(91)90142-h.PMID: 1776923
Saliva antimicrobial proteins may interact in a common system to influence the oral ecology. Clinical studies of antimicrobial protein action thus may require a multiple-protein approach. …Those findings may indicate that saliva antimicrobial proteins can a …1,111Cite
Nutritional value of processed rapeseed meal.
Paik IK.Adv Exp Med Biol. 1991;289:403-14. doi: 10.1007/978-1-4899-2626-5_29.PMID: 17168191,112Cite
Stokke T, Holte H, Erikstein B, Davies CL, Funderud S, Steen HB.Cytometry. 1991;12(2):172-8. doi: 10.1002/cyto.990120212.PMID: 1710961 Free article.1,113Cite
Effect of smokeless tobacco use in humans on mucosal immune factors.
Gregory RL, Kindle JC, Hobbs LC, Malmstrom HS.Arch Oral Biol. 1991;36(1):25-31. doi: 10.1016/0003-9969(91)90050-5.PMID: 17072691,114Cite
Purification and photoaffinity labeling of the I-Ak histocompatibility molecule.
Luescher IF, Unanue ER.J Immunol Methods. 1990 Dec 31;135(1-2):233-45. doi: 10.1016/0022-1759(90)90277-3.PMID: 2177076
Effective dissociation in the absence of detectable denaturation was observed for 10.3.6.2 and 40.LH monoclonal antibody at pH 3.5 and to a lesser extent at low concentrations of ammonium thiocyanate and guanidine thiocyanate at neutral pH. I-A k purified from cell …1,115Cite
Movement of tRNA but not the nascent peptide during peptide bond formation on ribosomes.
Odom OW, Picking WD, Hardesty B.Biochemistry. 1990 Dec 4;29(48):10734-44. doi: 10.1021/bi00500a004.PMID: 17030071,116Cite
Pharmacokinetics and bioavailability of erythromycin in pigeons (Columba livia).
Vanhaecke E, De Backer P, Remon JP, Devriese LA.J Vet Pharmacol Ther. 1990 Dec;13(4):356-60. doi: 10.1111/j.1365-2885.1990.tb00789.x.PMID: 2287027
The relative bioavailability after direct crop administration of erythromycin thiocyanate or erythromycin ethylsuccinate at a dosage rate of 100 mg/kg was less than 10%. …The use of erythromycin ethylsuccinate did not present any advantage in comparison with erythromycin …1,117Cite
Inhibition of HIV infectivity by lactoperoxidase-produced hypothiocyanite.
Pourtois M, Binet C, Van Tieghem N, Courtois P, Vandenabbeele A, Thiry L.J Biol Buccale. 1990 Dec;18(4):251-3.PMID: 2128884
HIV aliquots, from a supernatant of ARV-4 cell line, were mixed with an equal volume of a OSCN.generating glucose-glucose oxidase + thiocyanate-lacteroperoxidase solution, and then pre-incubated at 37 degrees C for periods of 30 secs to one hour. …1,118Cite
Pruitt KM, Kamau DN, Miller K, Månsson-Rahemtulla B, Rahemtulla F.Anal Biochem. 1990 Dec;191(2):278-86. doi: 10.1016/0003-2697(90)90220-4.PMID: 1964765
Regression equations have been determined which can be used to calculate concentrations of bovine lactoperoxidase (LPO), human salivary peroxidase (SPO), and human myeloperoxidase (MPO) from activities measured with the following donors: pyrogallol, guaiacol, 2,2′-azinobis(3-ethy …1,119Cite
Salivary defense mechanisms in juvenile periodontitis.
Saxén L, Tenovuo J, Vilja P.Acta Odontol Scand. 1990 Dec;48(6):399-407. doi: 10.3109/00016359009029071.PMID: 1705074
Lysozyme, lactoferrin, salivary peroxidase, myeloperoxidase, and thiocyanate concentrations were determined from both whole saliva and parotid saliva. The total concentrations of salivary IgA, IgG, and IgM were assayed. …1,120Cite
One interferon gamma receptor binds one interferon gamma dimer.
Fountoulakis M, Juranville JF, Maris A, Ozmen L, Garotta G.J Biol Chem. 1990 Nov 15;265(32):19758-67.PMID: 2147181 Free article.
Kinetic studies showed that the cross-linking of interferon gamma dimer to the soluble receptor proceeds through the intermediate formed by cross-linking one molecule of the interferon gamma dimer to the receptor. Reducing and dissociating agents inhibited complex formatio …1,121Cite
Nakamura T.Nihon Jinzo Gakkai Shi. 1990 Nov;32(11):1253-61.PMID: 2082058 Japanese.
Glomerular RNAs were isolated using guanidinium thiocyanate and then dotted onto nylon membrane. Filters were hybridized with specific cDNA probes and exposed to film for analysis by densitometer. …1,122Cite
Raha S, Merante F, Proteau G, Reed JK.Genet Anal Tech Appl. 1990 Nov;7(7):173-7. doi: 10.1016/0735-0651(90)90022-8.PMID: 1706192
The yield and quality of the RNA is comparable to the more widely employed methods requiring extensive preparatory steps such as extraction using guanidinium thiocyanate and subsequent CsCl gradient centrifugation. The RNA isolated using our procedure contains transcripts …1,123Cite
Assay of aspartylglycosylaminase by high-performance liquid chromatography.
Kaartinen V, Mononen I.Anal Biochem. 1990 Oct;190(1):98-101. doi: 10.1016/0003-2697(90)90140-5.PMID: 22851521,124Cite
Clinical evaluation of an automated chemical inhibition assay for lactate dehydrogenase isoenzyme 1.
Onigbinde TA, Wu AH, Johnson M, Wu YS, Collinsworth WL, Simmons MJ.Clin Chem. 1990 Oct;36(10):1819-22.PMID: 2208662
We evaluated an automated assay for lactate dehydrogenase (LD; EC 1.1.1.27) isoenzymes, supplied by Boehringer Mannheim Diagnostics (BMD) and based on selective chemical inhibition of non-LD-1 isoenzymes by guanidine thiocyanate. Results were compared with the Roche Isomun …1,125Cite
Centola GM, Mattox JH, Burde S, Leary JF.Mol Reprod Dev. 1990 Oct;27(2):130-5. doi: 10.1002/mrd.1080270207.PMID: 17010951,126Cite
Okwuasaba FK, Otubu JA, Udoh FV.Br J Pharmacol. 1990 Sep;101(1):133-9. doi: 10.1111/j.1476-5381.1990.tb12102.x.PMID: 2282456 Free PMC article.
The inhibitory effect of bath-appled Chlo, or acute and chronic pretreatment on twitch tension (MS) was not significantly antagonized by stepwise increase in extracellular Ca2 + (0.05-2.5 mM). Sodium thiocyanate (1-5 mM) reversed in a concentration-dependent manner the inh …1,127Cite
Gamma interferon-induced specific binding of tetanus toxin on the GG2EE macrophage cell line.
Blasi E, Pitzurra L, Burhan Fuad AM, Marconi P, Bistoni F.Scand J Immunol. 1990 Sep;32(3):289-92. doi: 10.1111/j.1365-3083.1990.tb02922.x.PMID: 21195161,128Cite
Murdoch A, Jenkinson EJ, Johnson GD, Owen JJ.J Immunol Methods. 1990 Aug 28;132(1):45-9. doi: 10.1016/0022-1759(90)90396-d.PMID: 21181601,129Cite
FITC-labeled lipopolysaccharide: use as a probe for liposomal membrane incorporation studies.
Trubetskoy VS, Koshkina NV, Omel’yanenko VG, L’vov VL, Dmitriev BA, Petrov AB, Torchilin VP.FEBS Lett. 1990 Aug 20;269(1):79-82. doi: 10.1016/0014-5793(90)81123-6.PMID: 2117560 Free article.1,130Cite
Alkaline serine proteinase from Thermomonospora fusca YX. Stability to heat and denaturants.
Kristjansson MM, Kinsella JE.Biochem J. 1990 Aug 15;270(1):51-5. doi: 10.1042/bj2700051.PMID: 2396992 Free PMC article.1,131Cite
Detection of dengue viral RNA in mosquito vectors by mixed phase and solution hybridization.
Olson KE, Blair CD, Beaty BJ.Mol Cell Probes. 1990 Aug;4(4):307-20. doi: 10.1016/0890-8508(90)90022-r.PMID: 2402251
A mixed phase hybridization technique was developed to detect dengue virus type 2 (DEN-2) RNA in pools of infected Aedes albopictus mosquitoes using radiolabelled RNA probes. This technique used a guanidine thiocyanate extraction procedure to simplify analyte preparation. …1,132Cite
The folding of staphylococcal nuclease in the presence of methanol or guanidine thiocyanate.
Nakano T, Fink AL.J Biol Chem. 1990 Jul 25;265(21):12356-62.PMID: 2373696 Free article.
The unfolding transition was determined as a function of guanidine thiocyanate in aqueous and 50% methanol solvents. The midpoints of the transitions were 0.30 and 0.20 M, respectively, at 2.1 degrees C. The kinetics of folding at 0 degree C were compared in aqueous, 50% m …1,133Cite
Synthetic antibody fragment as ligand in immunoaffinity chromatography.
Welling GW, Geurts T, van Gorkum J, Damhof RA, Drijfhout JW, Bloemhoff W, Welling-Wester S.J Chromatogr. 1990 Jul 20;512:337-43. doi: 10.1016/s0021-9673(01)89500-5.PMID: 2229233
Non-specific interactions could be abolished by washing the column with 0.05 M sodium thiocyanate in 20 mM tris-HCl (pH 7.4). Lysozyme was only bound to the antilysozyme adsorbent and could be eluted with 1 M sodium thiocyanate. …1,134Cite
Field trials of nitroscanate and mebendazole in dogs.
Genchi C, Traldi G, Manfredi MT.Vet Rec. 1990 Jul 7;127(1):24.PMID: 2385917 No abstract available.1,135Cite
Co-assembly of plasma and cellular fibronectins into fibrils in human fibroblast cultures.
Peters DM, Portz LM, Fullenwider J, Mosher DF.J Cell Biol. 1990 Jul;111(1):249-56. doi: 10.1083/jcb.111.1.249.PMID: 2114411 Free PMC article.1,136Cite
Estimation of cellular DNA content in cell lysates suitable for RNA isolation.
Rymaszewski Z, Abplanalp WA, Cohen RM, Chomczynski P.Anal Biochem. 1990 Jul;188(1):91-6. doi: 10.1016/0003-2697(90)90532-e.PMID: 1699451
In the present studies, a microfluorometric method has been modified from previous techniques to permit the quantitation of DNA in cell lysates prepared using an acid guanidinium thiocyanate-phenol (AGTP) solution from which RNA can subsequently be isolated. The lysate is …1,137Cite
Patacchini R, Maggi CA, Meli A.Naunyn Schmiedebergs Arch Pharmacol. 1990 Jul;342(1):72-7. doi: 10.1007/BF00178975.PMID: 1698263
Contractile responses to piperine, mustard oil and eugenol were partially tetrodotoxin and ruthenium red-sensitive, suggesting that activation of sensory terminals by these agents takes place indirectly, as well as by a direct action on sensory receptors. 4. The presence o …1,138Cite
Evaluation of automated urinary iodine methods: problems of interfering substances identified.
May W, Wu D, Eastman C, Bourdoux P, Maberly G.Clin Chem. 1990 Jun;36(6):865-9.PMID: 2357823
The apparently higher concentrations of UI we measured were due to interfering substances crossing the dialysis membrane and participating in the catalytic reaction. Thiocyanate (SCN) was one endogenous substance contributing to the increased measurement of UI. …1,139Cite
Courtois P, van Beers D, de Foor M, Mandelbaum IM, Pourtois M.J Biol Buccale. 1990 Jun;18(2):71-4.PMID: 2170348
HSV1 suspensions were pre-incubated in a lactoperoxidase thiocyanate oxidizing system before inoculation in MRC5 fibroblast cultures. This pre-treatment could either delay or even abolish the HSV1 cytopathic potentiality. …1,140Cite
Rudkowski R, Graham GG, Champion GD, Ziegler JB.Biochem Pharmacol. 1990 Jun 1;39(11):1687-95. doi: 10.1016/0006-2952(90)90112-x.PMID: 2160817
It has been suggested that the antiarthritic gold complex, aurothiomalate (Autm), is activated by its conversion to aurocyanide by polymorphonuclear leukocytes (PMN) which generate cyanide from thiocyanate. In an examination of this hypothesis, a study has been conducted o …1,141Cite
Halestrap AP, Davidson AM.Biochem J. 1990 May 15;268(1):153-60. doi: 10.1042/bj2680153.PMID: 2160810 Free PMC article.1,142Cite
Field trials of nitroscanate and mebendazole in dogs.
Vanparijs O, Vlaminck K.Vet Rec. 1990 Apr 7;126(14):341.PMID: 2339494 No abstract available.1,143Cite
Devanathan S, Dahl TA, Midden WR, Neckers DC.Proc Natl Acad Sci U S A. 1990 Apr;87(8):2980-4. doi: 10.1073/pnas.87.8.2980.PMID: 2109321 Free PMC article.
Thus, this strategy provides a simple way to rapidly prepare a large number of targeted phototoxic agents that can be used for the selective destruction with light of nearly any type of tissue or organism….1,144Cite
Fletcher MP, Stahl GL, Longhurst JC.J Leukoc Biol. 1990 Apr;47(4):355-65. doi: 10.1002/jlb.47.4.355.PMID: 21082281,145Cite
Strauss KI, Strayer DR, Gillespie DH.J Pharm Pharmacol. 1990 Apr;42(4):261-6. doi: 10.1111/j.2042-7158.1990.tb05404.x.PMID: 1974294
Samples were prepared by mixing 100 microL of blood with, 165 microL of 6 M guanidine thiocyanate (GuSCN) and 0.16 M EDTA pH 8.0, and freezing. Hybridizations were carried out with a [3H]poly(C) probe in 3 M GuSCN for 10 min at 37 degrees C. …1,146Cite
A micromethod for the isolation of total RNA from adipose tissue.
Tavangar K, Hoffman AR, Kraemer FB.Anal Biochem. 1990 Apr;186(1):60-3. doi: 10.1016/0003-2697(90)90572-q.PMID: 16940621,147Cite
Interferons exhibit temporally distinct regulation of two bovine macrophage Fc receptors.
Pontzer CH, Russell SW.J Leukoc Biol. 1990 Mar;47(3):258-64. doi: 10.1002/jlb.47.3.258.PMID: 21065631,148Cite
Steele-Mortimer OA, Meier-Ewert H, Löser R, Hasmann MJ.J Virol Methods. 1990 Mar;27(3):241-52. doi: 10.1016/0166-0934(90)90092-t.PMID: 1691199
On individual cells, with polyclonal antibodies, antigens were first detected at 12 h p.i., and the numbers of labeled cells were followed up to 96 h p.i. The efficacy of four antiviral agents was tested with this system. The results were in good agreement with those of pl …1,149Cite
Raby C, Lagorce JF, Jambut-Absil AC, Buxeraud J, Catanzano G.Endocrinology. 1990 Mar;126(3):1683-91. doi: 10.1210/endo-126-3-1683.PMID: 1689656
A number of compounds of pharmaceutical importance from a variety of chemical families, including thiocyanates, isothiocyanates, thiourea and derivatives, imidazoles, and various amines, were found to form charge transfer complexes with iodine. …These results suggest tha …1,150Cite
Arakawa T, Bhat R, Timasheff SN.Biochemistry. 1990 Feb 20;29(7):1914-23. doi: 10.1021/bi00459a036.PMID: 23314711,151Cite
Cunningham LW, Crews BC, Gettins P.Biochemistry. 1990 Feb 13;29(6):1638-43. doi: 10.1021/bi00458a040.PMID: 1692242
J. 203, 405-411] that 2,4-dinitrophenyl thiocyanate (DNPSCN) can block the conversion of “slow” to “fast” electrophoretic forms of human alpha 2-macroglobulin (alpha 2M) normally resulting from reaction of alpha 2M with methylamine. …1,152Cite
Hell JW, Maycox PR, Jahn R.J Biol Chem. 1990 Feb 5;265(4):2111-7.PMID: 1688846 Free article.1,153Cite
Bogaards JJ, van Ommen B, Falke HE, Willems MI, van Bladeren PJ.Food Chem Toxicol. 1990 Feb;28(2):81-8. doi: 10.1016/0278-6915(90)90014-e.PMID: 23410921,154Cite
Anionic mechanisms of zinc uptake across the human red cell membrane.
Kalfakakou V, Simons TJ.J Physiol. 1990 Feb;421:485-97. doi: 10.1113/jphysiol.1990.sp017957.PMID: 2161459 Free PMC article.
The second occurs in the presence of thiocyanate or salicylate ions and may represent transport of a neutral complex with Zn2+. 2. …1,155Cite
Puissant C, Houdebine LM.Biotechniques. 1990 Feb;8(2):148-9.PMID: 1690559 No abstract available.1,156Cite
Field trials of the anthelmintic efficacy of nitroscanate and mebendazole in dogs.
Genchi C, Traldi G, Manfredi MT.Vet Rec. 1990 Jan 27;126(4):77-80.PMID: 23093881,157Cite
Assay of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase.
Bozeman PM, Learn DB, Thomas EL.J Immunol Methods. 1990 Jan 24;126(1):125-33. doi: 10.1016/0022-1759(90)90020-v.PMID: 2154520
MPO catalyzes the oxidation of chloride to hypochlorus acid (HOCl), which also oxidized TMB, but chloride up to 20 mM had little effect on the assay. Both MPO and EPO catalyze thiocyanate oxidation, but the product (HOSCN) was a poor oxidant for TMB, and thiocyanate …1,158Cite
Fürst P, Pollack L, Graser TA, Godel H, Stehle P.J Chromatogr. 1990 Jan 19;499:557-69. doi: 10.1016/s0021-9673(00)97000-6.PMID: 23242141,159Cite
Franz M, Zahner H, Mehlhorn H, Striebel HP.Parasitol Res. 1990;76(5):393-400. doi: 10.1007/BF00933546.PMID: 23529161,160Cite
Effect of cadmium on membrane potential in isolated rat hepatocytes.
Martel J, Marion M, Denizeau F.Toxicology. 1990 Jan-Feb;60(1-2):161-72. doi: 10.1016/0300-483x(90)90170-l.PMID: 23159391,161Cite
Courtois P, Majerus P, Mandelbaum I, Pourtois M.Bull Mem Acad R Med Belg. 1990;145(3-4):175-82; discussion 182-3.PMID: 2207460 French.1,162Cite
Still J, Delahaut P, Coppe P, Kaeckenbeeck A, Perraudin JP.Ann Rech Vet. 1990;21(2):143-52.PMID: 21935961,163Cite
Cytotoxic properties of salivary oxidants.
Grisham MB, Ryan EM.Am J Physiol. 1990 Jan;258(1 Pt 1):C115-21. doi: 10.1152/ajpcell.1990.258.1.C115.PMID: 2154109
Salivary peroxidase and to a lesser extent myeloperoxidase are present in significant concentrations in saliva and catalyze the oxidation of thiocyanate anion (SCN-) by H2O2 to yield the potent oxidants hypothiocyanous acid (HOSCN) and its conjugate base hypothiocyanite an …1,164Cite
Effect of aminoglycoside antibiotics on the autolytic enzyme of Streptomyces griseus.
Szabó I, Penyige A, Barabás G, Barabás J.Arch Microbiol. 1990;155(1):99-102. doi: 10.1007/BF00291282.PMID: 21276701,165Cite
Roles of muscularis mucosae and myofibroblasts in the healing process of acetic acid-induced ulcer.
Nakamura M, Oda M, Inoue J, Nishizaki Y, Tsuchiya M.J Clin Gastroenterol. 1990;12 Suppl 1:S39-47. doi: 10.1097/00004836-199001001-00008.PMID: 21203231,166Cite
Rosette CD, DeTeresa PS, Pallavicini MG.Cytometry. 1990;11(4):547-51. doi: 10.1002/cyto.990110414.PMID: 2111761 Free article.1,167Cite
Jack M, Wood BJ, Berry DR.Microbios. 1990;62(250):37-46.PMID: 2110612
Attempts to isolate an active factor responsible for this inhibition from liquid culture and agar plates were not successful. The addition of sodium thiocyanate to the agar was found to increase the inhibition offered by the lactobacillus. The results indicate that hydroge …1,168Cite
Thilly CH, Contempre B, Vanderpas JB.Bull Mem Acad R Med Belg. 1990;145(11):440-8; discussion 448-50.PMID: 2099229 French.
From work undertaken by CEMUBAC in Ubangui Zaire, the role of thiocyanate overload is recalled while this work demonstrates for the first time in man an action of selenium supplementation (and thus deficiency) on thyroid function in iodine deficient areas. The extreme seve …1,169Cite
Larsen JK.Methods Cell Biol. 1990;33:227-34. doi: 10.1016/s0091-679x(08)60528-2.PMID: 1707485 No abstract available.1,170Cite
Investigations on the cytoprotective mechanisms of thiocyanate in rat gastric mucosa.
Casciano C, Kaminska GZ, Bennun A.Biochem Soc Trans. 1989 Dec;17(6):1113-4. doi: 10.1042/bst0171113.PMID: 2560742 No abstract available.1,171Cite
Activation of latent K+ uniport in mitochondria treated with the ionophore A23187.
Bernardi P, Angrilli A, Ambrosin V, Azzone GF.J Biol Chem. 1989 Nov 15;264(32):18902-6.PMID: 2509471 Free article.
A23187-treated mitochondria passively swell in K+ thiocyanate at neutral pH, under conditions where the H+-K+ antiporter appears to be silent. …1,172Cite
[Derivatives of thioallophanic acid with anthelmintic activity].
Sluka J, Zikán V, Sova M, Danĕk J.Cesk Farm. 1989 Nov;38(9):414-7.PMID: 2635646 Czech.
A reaction of potassium thiocyanate with methyl and ethyl ester of chloroformic acid (I-II) resulted in methoxy- and ethoxycarbonyl isothiocyanates which through an addition reaction with various primary and secondary amines, diamines and hydrazines yielded the perinently …1,173Cite
Synthesis and antimicrobial activity of some new 2,5-imidazolidinediones.
Mohamed AM, el-Sharief AM, Ammar YA, Aly MM.Pharmazie. 1989 Nov;44(11):765-7.PMID: 2616624
Reaction of 6a with acetyl chloride, aromatic aldehydes, arylsulphonyl chlorides, phthalic acid anhydrides and isocyanates or thiocyanates furnished 6d, furnished the acetyl-amido derivative 6b, the benzylidenimino derivatives 7a-d, the arylsulphonamido derivatives 8a-b, t …1,174Cite
Evidence for furosemide-sensitive Na+-K+-Cl- co-transport in lactating rat mammary tissue.
Shennan DB.Q J Exp Physiol. 1989 Nov;74(6):927-38. doi: 10.1113/expphysiol.1989.sp003363.PMID: 2594942 Free article.1,175Cite
Cyanide release from sodium nitroprusside during coronary bypass in hypothermia.
Lundquist P, Rosling H, Tydén H.Acta Anaesthesiol Scand. 1989 Nov;33(8):686-8. doi: 10.1111/j.1399-6576.1989.tb02992.x.PMID: 2589001
We conclude that SNP is broken down to cyanide even under hypothermia and that low body temperature may impair the conversion of cyanide to thiocyanate, probably by affecting the metabolic pathways providing the sulphur substrate. …1,176Cite
Siragusa GR, Johnson MG.Appl Environ Microbiol. 1989 Nov;55(11):2802-5. doi: 10.1128/aem.55.11.2802-2805.1989.PMID: 2516432 Free PMC article.
The lactoperoxidase-thiocyanate-H2O2 system (LP system), consisting of lactoperoxidase (0.37 U/ml), KSCN (0.3 mM), and H2O2 (0.3 mM), delayed but did not prevent growth of L. monocytogenes Scott A at 5, 10, 20, and 30 degrees C in broth and at 20 degrees C in milk. …1,177Cite
On the regulation of the mitochondrial inner membrane anion channel by magnesium and protons.
Beavis AD, Powers MF.J Biol Chem. 1989 Oct 15;264(29):17148-55.PMID: 2477365 Free article.1,178Cite
A study on the aetiology of endemic goitre in lowland Burma.
Khin-Maung-Naing, Cho-Nwe-Oo, Tin-Tin-Oo, Thane-Toe.Eur J Clin Nutr. 1989 Oct;43(10):693-8.PMID: 2533070
Low urinary iodine excretion and high 24-h uptake of 131I by the thyroids of the subjects indicated iodine deficiency which was further confirmed by direct chemical analysis of diet samples. The serum thiocyanate level of non-smokers from this area was found to be low, whi …1,179Cite
Membrane potential, anion and cation conductances in Ehrlich ascites tumor cells.
Lambert IH, Hoffmann EK, Jørgensen F.J Membr Biol. 1989 Oct;111(2):113-31. doi: 10.1007/BF01871776.PMID: 24823601,180Cite
Effect of calcium on the interactions between Ca2+-ATPase molecules in sarcoplasmic reticulum.
Keresztes T, Jona I, Pikula S, Vegh M, Mullner N, Papp S, Martonosi A.Biochim Biophys Acta. 1989 Sep 18;984(3):326-38. doi: 10.1016/0005-2736(89)90300-3.PMID: 25500781,181Cite
Enzymatic amplification of RNA purified from crude cell lysate by reversible target capture.
Thompson JD, Decker S, Haines D, Collins RS, Feild M, Gillespie D.Clin Chem. 1989 Sep;35(9):1878-81.PMID: 2673585
Here we summarize progress in the development of a strategy for performing molecular hybridization directly in lysate of biological samples dissolved in solutions containing the chaotropic agent, guanidine thiocyanate. Hybrids are purified by a process referred to as “reve …1,182Cite
Quantitative assays based on the use of replicatable hybridization probes.
Lomeli H, Tyagi S, Pritchard CG, Lizardi PM, Kramer FR.Clin Chem. 1989 Sep;35(9):1826-31.PMID: 2673578
Hybridizations were carried out in a solution containing the chaotropic salt, guanidine thiocyanate. Probe-target hybrids were isolated by reversible target capture on paramagnetic particles. …1,183Cite
Beta-N-oxalylamino-L-alanine action on glutamate receptors.
Ross SM, Roy DN, Spencer PS.J Neurochem. 1989 Sep;53(3):710-5. doi: 10.1111/j.1471-4159.1989.tb11762.x.PMID: 2547898
L-BOAA was most active in displacing thiocyanate (KSCN)-sensitive specific tritiated (RS)-alpha-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) binding (i.e., QA receptor) (Ki = 0.76 microM) with a rank-order potency of QA greater than kainate greater than N-methyl-D-a …1,184Cite
Nucleic acid hybridization assays employing dA-tailed capture probes. I. Multiple capture methods.
Morrissey DV, Lombardo M, Eldredge JK, Kearney KR, Groody EP, Collins ML.Anal Biochem. 1989 Sep;181(2):345-59. doi: 10.1016/0003-2697(89)90255-8.PMID: 25105531,185Cite
A noise-free molecular hybridization procedure for measuring RNA in cell lysates.
Thompson J, Solomon R, Pellegrino M, Sakai K, Lewin M, Feild M, Castrovinci M, Sacramone L, Gillespie D.Anal Biochem. 1989 Sep;181(2):371-8. doi: 10.1016/0003-2697(89)90257-1.PMID: 2479299
Cell lysates were prepared in 5 M guanidine thiocyanate, then RNA molecules in the lysates were hybridized with two probes, a 32P-labeled RNA “label probe” which provided signal and an oligodeoxyribonucleotide “capture probe” containing a poly(dA) tail which provided a mec …1,186Cite
Characterization of a P-type ATPase of the archaebacterium Methanococcus voltae.
Dharmavaram RM, Konisky J.J Biol Chem. 1989 Aug 25;264(24):14085-9.PMID: 2527232 Free article.1,187Cite
Induction of fusion in aggregated and nonaggregated liposomes bearing cationic detergents.
Keren-Zur M, Beigel M, Loyter A.Biochim Biophys Acta. 1989 Aug 7;983(2):253-8. doi: 10.1016/0005-2736(89)90241-1.PMID: 2758061
Fusion in such aggregated liposomes was observed by the addition of chaotropic anions, such as nitrate or thiocyanate, or by PASP. A variety of other quaternary ammonium detergents behaved similarly to DEBDA[OH] in their ability to confer fusogenic properties upon PC/chol …1,188Cite
Staphylococcus aureus phagocytosis. A new cytofluorometric method using FITC and paraformaldehyde.
Cantinieaux B, Hariga C, Courtoy P, Hupin J, Fondu P.J Immunol Methods. 1989 Jul 26;121(2):203-8. doi: 10.1016/0022-1759(89)90161-0.PMID: 25035601,189Cite
Burdon DW.J Med Microbiol. 1989 Jun;29(2):145-57. doi: 10.1099/00222615-29-2-145.PMID: 2659797
Such properties, with the exception of growth in cell-free medium, are shared by “unconventional agents” such as those of Creutzfeldt-Jakob disease and scrapie. Further comparison of the properties of the intestinal agent and of slow viruses revealed additional shared char …1,190Cite
Saito K, Yamamoto K, Nagayama I, Uemura J, Kuzuya T.Endocrinol Jpn. 1989 Jun;36(3):325-33. doi: 10.1507/endocrj1954.36.325.PMID: 2555140 Free article.1,191Cite
Cheever AW, Deb S.Am J Trop Med Hyg. 1989 Jun;40(6):620-8. doi: 10.4269/ajtmh.1989.40.620.PMID: 25008561,192Cite
Binding of thiocyanate to lactoperoxidase: 1H and 15N nuclear magnetic resonance studies.
Modi S, Behere DV, Mitra S.Biochemistry. 1989 May 30;28(11):4689-94. doi: 10.1021/bi00437a027.PMID: 2548589
The binding of thiocyanate to lactoperoxidase (LPO) has been investigated by 1H and 15N NMR spectroscopy. 1H NMR of LPO shows that the major broad heme methyl proton resonance at about 61 ppm is shifted upfield by addition of the thiocyanate, indicating binding of t …1,193Cite
Issopoulos PB.Analyst. 1989 May;114(5):627-30. doi: 10.1039/an9891400627.PMID: 2757232
The results obtained for the determination of iron(III) using the described procedure and the thiocyanate method were compared statistically by means of the Student t-test and no significant difference was found….1,194Cite
Davies KP, Zahner H, Köhler P.Exp Parasitol. 1989 May;68(4):382-91. doi: 10.1016/0014-4894(89)90123-9.PMID: 27216321,195Cite
Nüsse M, Jülch M, Geido E, Bruno S, Di Vinci A, Giaretti W, Ruoss K.Cytometry. 1989 May;10(3):312-9. doi: 10.1002/cyto.990100310.PMID: 2496957 Free article.1,196Cite
Differential induction of macrophage GSIB4-binding activity.
Tabor DR, Larry CH, Jacobs RF.J Leukoc Biol. 1989 May;45(5):452-7. doi: 10.1002/jlb.45.5.452.PMID: 24961931,197Cite
Takumida M, Urquiza R, Bagger-Sjöbäck D, Wersäll J.J Laryngol Otol. 1989 Apr;103(4):357-62. doi: 10.1017/s0022215100108953.PMID: 25659461,198Cite
Cyanide metabolism in the isolated, perfused, bloodless hindlimbs or liver of the rat.
Devlin DJ, Smith RP, Thron CD.Toxicol Appl Pharmacol. 1989 Apr;98(2):338-49. doi: 10.1016/0041-008x(89)90238-x.PMID: 2540545
After a period of equilibration, samples of the perfusate were taken periodically for cyanide (CN) and thiocyanate (SCN) analyses. The results were used to determine CN extraction ratios or clearance and rates of SCN formation. …1,199Cite
[5,6-bis-(3-alkoxy-carbonyl thio-ureido) benzimidazoles with anthelmintic activity].
Sluka J, Zikán V, Danĕk J.Cesk Farm. 1989 Apr;38(3):118-20.PMID: 2505937 Czech.
The reaction of potassium thiocyanate with the methyl- and ethyl esters of chloroformic acid (V-VI) in acetone resulted in methoxy- and ethoxycarbonylisothiocyanates which were converted without isolation by means of an addition reaction with 2-alkyl-5,6-diaminobenzimidazo …1,200Cite
Goyal R, Tardif R, Brodeur J.Can J Physiol Pharmacol. 1989 Mar;67(3):207-12. doi: 10.1139/y89-035.PMID: 2663124
Respective urinary metabolites, hydroxyethylmercapturic acid, cyanoethylmercapturic acid, thiocyanate, and ethylene glycol, were quantified to estimate the extent to which each compound was metabolized. …
Antimicrobial factors in whole saliva of human infants: a longitudinal study.
Hyyppä T, Karhuvaara L, Tenovuo J, Lumikari M, Vilja P.Pediatr Dent. 1989 Mar;11(1):30-6.PMID: 2626337
Because early childhood is an important period for the colonization of bacteria in the primary dentition, it is possible that antimicrobial factors in saliva may modify these early events. In this study we have followed longitudinally 33 children from predentate to dentate …1,202Cite
Transport characteristics of [3H]-chlorpromazine across rat small intestinal brush border membrane.
Saitoh H, Kawai S, Iseki K, Miyazaki K, Arita T.J Pharm Pharmacol. 1989 Mar;41(3):200-2. doi: 10.1111/j.2042-7158.1989.tb06431.x.PMID: 2568451
The transport of chlorpromazine into the intravesicular space was facilitated by the transmembrane electrical potential difference (inside negative) induced by valinomycin or sodium thiocyanate. This facilitating effect was observed only when the transmembrane electrical p …1,203Cite
Shioi J, Naito S, Ueda T.Biochem J. 1989 Mar 1;258(2):499-504. doi: 10.1042/bj2580499.PMID: 2565109 Free PMC article.
This ATP-dependent delta psi was reduced by thiocyanate anion (SCN-), a delta psi dissipator, or carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone (FCCP), a protonmotive-force dissipator. …1,204Cite
Lectin-binding sites in normal human testis.
Wollina U, Schreiber G, Zollmann C, Hipler C, Günther E.Andrologia. 1989 Mar-Apr;21(2):127-30.PMID: 24693621,205Cite
Purification and properties of the intact P-700 and Fx-containing Photosystem I core protein.
Parrett KG, Mehari T, Warren PG, Golbeck JH.Biochim Biophys Acta. 1989 Feb 28;973(2):324-32. doi: 10.1016/s0005-2728(89)80439-6.PMID: 2537101
The intact Photosystem I core protein, containing the psaA and psaB polypeptides, and electron transfer components P-700 through FX, was isolated from cyanobacterial and higher plant Photosystem I complexes with chaotropic agents followed by sucrose density ultracentrifuga …1,206Cite
Bott M, Thauer RK.Eur J Biochem. 1989 Feb 1;179(2):469-72. doi: 10.1111/j.1432-1033.1989.tb14576.x.PMID: 2537211 Free article.1,207Cite
Transport of glutamine in rat intestinal brush-border membrane vesicles.
Van Voorhis K, Said HM, Ghishan FK, Abumrad NN.Biochim Biophys Acta. 1989 Jan 16;978(1):51-5. doi: 10.1016/0005-2736(89)90497-5.PMID: 24924321,208Cite
Relative effectiveness of various ions on the solubility and crystal growth of lysozyme.
Ries-Kautt MM, Ducruix AF.J Biol Chem. 1989 Jan 15;264(2):745-8.PMID: 2910863 Free article.
Crystals obtained with each salt were characterized by x-ray diffraction. Lysozyme thiocyanate and nitrate crystals belong to the monoclinic system, whereas all the others have a tetragonal lattice….1,209Cite
Lawrence JF, Charbonneau CF, Page BD, Lacroix GM.J Chromatogr. 1989 Jan 13;462:419-25. doi: 10.1016/s0021-9673(00)91371-2.PMID: 2738132 No abstract available.1,210Cite
Quantitation of HIV-1 RNA in blood cells of ARC and AIDS patients.
Solomon R, Thompson J, Gillespie D.J Clin Lab Anal. 1989;3(5):282-6. doi: 10.1002/jcla.1860030505.PMID: 2809878
Peripheral blood mononuclear cells from HIV-1-infected persons were mixed with 5 M guanidine thiocyanate, and HIV-1-specific probes were hybridized with target RNA directly in the lysate. …1,211Cite
The inactivation of rhodanese by nitrite and inhibition by other anions in vitro.
Alexander K, Procell LR, Kirby SD, Baskin SI.J Biochem Toxicol. 1989 Spring;4(1):29-33. doi: 10.1002/jbt.2570040106.PMID: 2769694
Cyanide detoxification in mammals occurs, in part, by sulfur transfer by rhodanese to form the less toxic thiocyanate. Thiosulfate and nitrite are often used in combination for the treatment of cyanide intoxication. …1,212Cite
[The peroxidase content of human tears].
Buchberger W, Rieger G.Fortschr Ophthalmol. 1989;86(2):164-6.PMID: 2544495 German.
Earlier investigations by van Haeringen et al. established a POD level in human tears of 10(3) units/l, yet the thiocyanate concentration was only about 0.2 mmol/l. Therefore van Haeringen et al. excluded the existence of a POD-thiocyanate-hydrogenperoxide antibacte …1,213Cite
Nakamura M, Oda M, Nishizaki Y, Kaneko K, Azuma T, Tsuchiya M.Scand J Gastroenterol Suppl. 1989;162:150-3. doi: 10.3109/00365528909091148.PMID: 25126351,214Cite
Wada Y, Kawamoto K, Oka S, Yamashita T, Kumazawa T, Matsumura H.Life Sci. 1989;44(4):259-64. doi: 10.1016/0024-3205(89)90183-5.PMID: 24926281,215Cite
Bhatia SC, Revankar SN, Bharucha ED, Desai ND, Sahajwalla CG.J Chromatogr. 1988 Dec 29;434(1):303-7.PMID: 3243828 No abstract available.1,216Cite
Maximal calcium extrusion capacity and stoichiometry of the human red cell calcium pump.
Dagher G, Lew VL.J Physiol. 1988 Dec;407:569-86. doi: 10.1113/jphysiol.1988.sp017432.PMID: 3151497 Free PMC article.
During cobalt-exposed calcium efflux, the calcium content of subpopulations of cells, with and without active Ca2+-sensitive K+ channels, investigated by post-incubation of samples in low-K+, thiocyanate (SCN-) media (modified from Garcia-Sancho & Lew, 1988a), was simi …1,217Cite
Properties of the residual calcium pools in human red cells exposed to transient calcium loads.
García-Sancho J, Lew VL.J Physiol. 1988 Dec;407:541-56. doi: 10.1113/jphysiol.1988.sp017430.PMID: 3151495 Free PMC article.1,218Cite
García-Sancho J, Lew VL.J Physiol. 1988 Dec;407:505-22. doi: 10.1113/jphysiol.1988.sp017428.PMID: 3151493 Free PMC article.
The method was based (i) on the ability of cytoplasmic Ca2+ to activate K+-selective channels in the membrane, and (ii) on the demonstration here that thiocyanate (SCN-) is a non-limiting co-ion for rapid net KSCN efflux and cell shrinkage in the cold. 3. …1,219Cite
Malhotra K, Salmon D, Le Bras J, Vilde JL.Infect Immun. 1988 Dec;56(12):3305-9. doi: 10.1128/iai.56.12.3305-3309.1988.PMID: 2846444 Free PMC article.
The viability of Plasmodium falciparum in culture was assessed by [3H]hypoxanthine incorporation during 24 h of incubation with lactoperoxidase, glucose-glucose oxidase, hydrogen peroxide, halides, or thiocyanate, alone or in combination. Synergistic inhibition was produce …1,220Cite
Hoff KA.Appl Environ Microbiol. 1988 Dec;54(12):2949-52. doi: 10.1128/aem.54.12.2949-2952.1988.PMID: 2464967 Free PMC article.1,221Cite
Studies on the ionic mechanism for the neuromodulatory actions of adenosine in the brain.
Michaelis ML, Johe KK, Moghadam B, Adams RN.Brain Res. 1988 Nov 15;473(2):249-60. doi: 10.1016/0006-8993(88)90854-2.PMID: 2466522
In our initial series of studies, the effects of adenosine analogs on depolarization-induced 45Ca influx into synaptosomes were examined, but no reduction in 45Ca uptake was observed in the presence of these agents, regardless of whether synaptosomes were depolarized by KC …1,222Cite
Stimulatory effects of anti-rheumatic drugs on human neutrophil functions.
Oben JA, Foreman JC.Immunopharmacology. 1988 Nov-Dec;16(3):157-65. doi: 10.1016/0162-3109(88)90004-5.PMID: 31509701,223Cite
Turchinskiĭ MF, Aĭnbinder EI, Sverdlov ED.Mol Biol (Mosk). 1988 Nov-Dec;22(6):1545-52.PMID: 2855255 Russian.1,224Cite
Hong CY, Huang JJ, Wu P, Lo SJ, Wei YH.Andrologia. 1988 Nov-Dec;20(6):516-20.PMID: 24657071,225Cite
Cl(-)-dependent ATP-driven H+ transport in rabbit renal cortical endosomes.
Hilden SA, Johns CA, Madias NE.Am J Physiol. 1988 Nov;255(5 Pt 2):F885-97. doi: 10.1152/ajprenal.1988.255.5.F885.PMID: 24610971,226Cite
[Studies on new antiparasitic agents: synthesis of nithiocyamine analogs].
Yao RH, Huang LS.Yao Xue Xue Bao. 1988 Jul;23(7):498-503.PMID: 3064547 Chinese. No abstract available.1,227Cite
Electrogenicity of phosphate transport by renal brush-border membranes.
Béliveau R, Ibnoul-Khatib H.Biochem J. 1988 Jun 15;252(3):801-6. doi: 10.1042/bj2520801.PMID: 3421922 Free PMC article.
Anion substitution studies showed that potency of the effect of the co-anions was in the order thiocyanate greater than nitrate greater than chloride greater than isethionate greater than gluconate greater than sulphate, which correlates with the known permeability of the …1,228Cite
Lewinsohn DM, Nickoloff BJ, Butcher EC.J Immunol Methods. 1988 May 25;110(1):93-100. doi: 10.1016/0022-1759(88)90087-7.PMID: 31314381,229Cite
Effects of liposomes on permeability of various compounds through rabbit corneas.
Morimoto K, Nakamura T, Nakai T, Morisaka K.Arch Int Pharmacodyn Ther. 1988 May-Jun;293:7-13.PMID: 31389531,230Cite
Fixation and long-term storage of human lymphocytes for surface marker analysis by flow cytometry.
Lal RB, Edison LJ, Chused TM.Cytometry. 1988 May;9(3):213-9. doi: 10.1002/cyto.990090305.PMID: 3132354 Free article.1,231Cite
Toxicity of methylenebisthiocyanate (MBT) to several freshwater organisms.
Maas-Diepeveen JL, van Leeuwen CJ.Bull Environ Contam Toxicol. 1988 Apr;40(4):517-24. doi: 10.1007/BF01688375.PMID: 3370346 No abstract available.1,232Cite
Chaouki ML, Maoui R, Benmiloud M.Clin Endocrinol (Oxf). 1988 Apr;28(4):399-408. doi: 10.1111/j.1365-2265.1988.tb03671.x.PMID: 3191604
When comparing the data collected in six different villages of the area, significant negative correlations were found between the decrease in urinary iodide and iodide/thiocyanate ratio (I/SCN) and the increase in prevalences of visible goitres, endemic cretinism and trans …1,233Cite
Gråhn E, Tenovuo J, Lehtonen OP, Eerola E, Vilja P.Acta Odontol Scand. 1988 Apr;46(2):67-74. doi: 10.3109/00016358809004749.PMID: 3164564
The association of salivary antibody (total IgA, IgG, and IgM and antibodies reactive with Streptococcus mutans) and non-antibody (lysozyme, lactoferrin, salivary peroxidase, myeloperoxidase, hypothiocyanite, thiocyanate) defense factors with oral health (past and present …1,234Cite
Effects of a beta-blocking agent, timolol maleate, on saliva in healthy volunteers.
Laurikainen K, Laurikainen E, Tenovuo J, Kaila T, Vilja P.Scand J Dent Res. 1988 Apr;96(2):121-7. doi: 10.1111/j.1600-0722.1988.tb01418.x.PMID: 2451271
The levels of total protein, lysozyme, IgA, IgG and IgM, salivary peroxidase, myeloperoxidase, lactoferrin, amylase, thiocyanate (SCN-), and hypothiocyanite (OSCN-) were analyzed from saliva samples. Drug levels were measured both from parotid saliva and blood samples. …1,235Cite
Samuel D, Patt RJ, Abuknesha RA.J Immunol Methods. 1988 Mar 16;107(2):217-24. doi: 10.1016/0022-1759(88)90221-9.PMID: 31262421,236Cite
Meers P, Feigenson GW.Biochim Biophys Acta. 1988 Mar 3;938(3):469-82. doi: 10.1016/0005-2736(88)90145-9.PMID: 3349073 Free article.1,237Cite
Detectability and measurability of amoscanate in plasma by TLC and HPLC.
Kofi-Tsekpo WM, Karekezi CW.Drugs Exp Clin Res. 1988;14(1):31-7.PMID: 33911041,238Cite
The mechanism of peroxidase-mediated cytotoxicity. II. Role of the heme moiety.
Lin H, McFaul SJ, Brady JC, Everse J.Proc Soc Exp Biol Med. 1988 Jan;187(1):7-13. doi: 10.3181/00379727-187-42629.PMID: 3340620
This conclusion was confirmed by demonstrating that microperoxidase, hemin, and hematoheme also exert cytotoxic activity in the presence of hydrogen peroxide and iodide, the kinetics of which were identical to those obtained with the peroxidases. Fluoride, bromide, and thiocya …1,239Cite
Electrogenic ATP-dependent Cl- transport by plasma membrane vesicles from Aplysia intestine.
Gerencser GA.Am J Physiol. 1988 Jan;254(1 Pt 2):R127-33. doi: 10.1152/ajpregu.1988.254.1.R127.PMID: 3337266
Second, ATP plus Cl- increased intravesicular negativity measured by lipophilic triphenylmethylphosphonium distribution across the vesicular membrane. Third, both vanadate and thiocyanate inhibited the ATP plus Cl–dependent intravesicular negativity. These results are con …1,240Cite
Porretta GC, Cerreto F, Fioravanti R, Scalzo M, Fischetti M, Riccardi F, Capezzone de Joannon A, de Feo G, Mazzanti G, Tolu L.Farmaco Sci. 1988 Jan;43(1):15-28.PMID: 3294041
The synthesis, antifungal and pharmacological activities of new 1,4-diarylimidazoles are reported. Antimicrobial data in comparison with antifungal antibiotic pyrrolnitrin pointed out that the 1,4-diaryl-2-mercaptoimidazole derivatives were inactive and all 1,4-diarylimida …1,241Cite
Eriksson AE, Kylsten PM, Jones TA, Liljas A.Proteins. 1988;4(4):283-93. doi: 10.1002/prot.340040407.PMID: 3151020
The binding of four inhibitors–mercuric ion, 3-acetoxymercuri-4-aminobenzenesulfonamide (AMS), acetazolamide (Diamox), and thiocyanate ion–to human carbonic anhydrase II (HCA II) has been studied with X-ray crystallography. …Thus the tetrahedral geometry of the zinc is …1,242Cite
The mechanism of cyanide intoxication and its antagonism.
Way JL, Leung P, Cannon E, Morgan R, Tamulinas C, Leong-Way J, Baxter L, Nagi A, Chui C.Ciba Found Symp. 1988;140:232-43. doi: 10.1002/9780470513712.ch14.PMID: 3073059 Review.
One mechanism of cyanide antagonism is by sequestering cyanide with methaemoglobin to form cyanmethaemoglobin and another mechanism is detoxifying with a sulphur donor to thiocyanate. Questions have been raised with regard to these classical mechanisms. Oxygen with nitrite …1,243Cite
[The role of goitrogenic factors distinct from iodine deficiency in the etiology of goiter].
Delange F.Ann Endocrinol (Paris). 1988;49(4-5):302-5.PMID: 3059971 Review. French.
Iodine excess, especially in the newborn infants, lithium and thiocyanate overload resulting from smoking habits can be responsible for the development of goiter in non endemic areas….1,244Cite
Preparation and characterization of biotinylated probes for the beta-interferon receptor.
Fournier A, Zhang ZQ, Tan YH.Int J Biochem. 1988;20(10):1151-7. doi: 10.1016/0020-711x(88)90261-3.PMID: 2977763
The biotinylated recHuIFN beta binds specifically and reversibly to succinoylavidin or guanidine thiocyanate-stripped succinoylavidin linked to a Sepharose matrix. 6. Comparison of the competition curves obtained with [14C]biotin and [3H]biotinyl recHuIFN, in the presence …1,245Cite
Tardif R, Talbot D, Gérin M, Brodeur J.Toxicol Lett. 1987 Dec;39(2-3):255-61. doi: 10.1016/0378-4274(87)90241-4.PMID: 3686555
Urinary metabolites measured 24 h after administration were 2-cyanoethylmercapturic acid (CMA), 2-hydroxyethylmercapturic acid (HMA) and thiocyanate (TCN). In all 3 series of experiments, the relationship between excretion of total urinary metabolites and the degree of exp …1,246Cite
Oda T, Sato F, Maeda H.J Natl Cancer Inst. 1987 Dec;79(6):1205-11.PMID: 29619081,247Cite
Isolation of intact high-molecular-weight DNA by using guanidine isothiocyanate.
Lippke JA, Strzempko MN, Raia FF, Simon SL, French CK.Appl Environ Microbiol. 1987 Oct;53(10):2588-9. doi: 10.1128/aem.53.10.2588-2589.1987.PMID: 3426222 Free PMC article.1,248Cite
Effect of some benzyl thiocyanate analogs on tetracycline production.
Priestap HA.J Antibiot (Tokyo). 1987 Sep;40(9):1341-3. doi: 10.7164/antibiotics.40.1341.PMID: 3680045 Free article. No abstract available.1,249Cite
Salivary peroxidase: an important part of our defense against oxygen toxicity.
Carlsson J.J Oral Pathol. 1987 Sep;16(8):412-6. doi: 10.1111/j.1600-0714.1987.tb02077.x.PMID: 2826736 Review.
In saliva the most important part of this defense is salivary peroxidase, which detoxifies hydrogen peroxide in the presence of thiocyanate by converting it into hypothiocyanite, dioxygen and water. In addition, hypothiocyanite stops hydrogen peroxide production by the ora …1,250Cite
The purified ATPase from chromaffin granule membranes is an anion-dependent proton pump.
Moriyama Y, Nelson N.J Biol Chem. 1987 Jul 5;262(19):9175-80.PMID: 2885327 Free article.
The ATP-dependent proton uptake activity of the reconstituted enzyme was absolutely dependent on the presence of Cl- or Br- outside the vesicles, whereas sulfate, acetate, formate, nitrate, and thiocyanate were inhibitory. Sulfate inhibition seems to be due to competition …1,251Cite
Mullins FG, Kirkbright GF.Analyst. 1987 May;112(5):701-3. doi: 10.1039/an9871200701.PMID: 3605632 No abstract available.1,252Cite
Cole PV, Vesey CJ.Br J Anaesth. 1987 May;59(5):531-5. doi: 10.1093/bja/59.5.531.PMID: 3580232 Free article. Clinical Trial.
Plasma and red cell cyanide, and plasma thiocyanate, concentrations were measured in 30 patients undergoing elective nitroprusside-induced hypotension. …Improved cyanide metabolism was further demonstrated by a sharp increase in mean plasma thiocyanate concentrati …1,253Cite
Cyanide poisoning from propionitrile exposure.
Bismuth C, Baud FJ, Djeghout H, Astier A, Aubriot D.J Emerg Med. 1987 May-Jun;5(3):191-5. doi: 10.1016/0736-4679(87)90178-8.PMID: 3429812
Treatment with hydroxycobalamin and sodium thiosulfate produced complete symptom resolution within an hour. Serial blood cyanide and thiocyanate levels documented a rapid decrease in cyanide and concomitant increase in thiocyanate. …1,254Cite
Midoux P, Roche AC, Monsigny M.Cytometry. 1987 May;8(3):327-34. doi: 10.1002/cyto.990080314.PMID: 3109859 Free article.1,255Cite
Fluorescent staining of nuclei in filamentous fungi.
Panwar R, Singh US, Singh RS.Stain Technol. 1987 May;62(3):205-8. doi: 10.3109/10520298709107994.PMID: 2441499 No abstract available.1,256Cite
Ultrastructural changes in the respiratory tract of rats following methyl isocyanate inhalation.
Dinsdale D, Nemery B, Sparrow S.Arch Toxicol. 1987 Apr;59(6):385-90. doi: 10.1007/BF00316202.PMID: 36063831,257Cite
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.
Chomczynski P, Sacchi N.Anal Biochem. 1987 Apr;162(1):156-9. doi: 10.1006/abio.1987.9999.PMID: 2440339
A new method of total RNA isolation by a single extraction with an acid guanidinium thiocyanate-phenol-chloroform mixture is described. The method provides a pure preparation of undegraded RNA in high yield and can be completed within 4 h. …1,258Cite
Gee SJ, LeValley SE, Tyson CA.Toxicol Appl Pharmacol. 1987 Mar 30;88(1):24-34. doi: 10.1016/0041-008x(87)90266-3.PMID: 3564031
CoCl2 produced neither cyanmethemoglobin nor thiocyanate in appreciable quantities nor required erythrocytes for antagonism. Na2S2O3 converted cyanide to thiocyanate and reversed ATP depression without erythrocytes in the medium. …1,259Cite
Jacobs DE.J Vet Pharmacol Ther. 1987 Mar;10(1):23-9. doi: 10.1111/j.1365-2885.1987.tb00072.x.PMID: 35861191,260Cite
Ross DC, McIntosh DB.J Biol Chem. 1987 Feb 15;262(5):2042-9.PMID: 2950084 Free article.1,261Cite
[No authors listed]Am J Public Health. 1987 Feb;77(2):230-6. doi: 10.2105/ajph.77.2.230.PMID: 3451742 Free PMC article. No abstract available.1,262Cite
Bruce JI.Int J Parasitol. 1987 Feb;17(1):131-40. doi: 10.1016/0020-7519(87)90034-8.PMID: 3294627 Review. No abstract available.1,263Cite
Characterization of lactoferrin interaction with Streptococcus mutans.
Lassiter MO, Newsome AL, Sams LD, Arnold RR.J Dent Res. 1987 Feb;66(2):480-5. doi: 10.1177/00220345870660021601.PMID: 3114344
LF-killing could be enhanced by the presence of thiocyanate and inhibited by catalase and lactoperoxidase; however, bovine serum albumin was equally effective as an inhibitor. …1,264Cite
Age-dependent oral bioavailability of erythromycin thiocyanate in calves.
Soback S, Ziv G, Kurtz B, Risenberg R.Zentralbl Veterinarmed A. 1987 Feb;34(2):102-7. doi: 10.1111/j.1439-0442.1987.tb00261.x.PMID: 3109157 No abstract available.1,265Cite
Effects of variations in pH and hypothiocyanite concentrations on S. mutans glucose metabolism.
Mansson-Rahemtulla B, Baldone DC, Pruitt KM, Rahemtulla F.J Dent Res. 1987 Feb;66(2):486-91. doi: 10.1177/00220345870660021701.PMID: 30408251,266Cite
Antimicrobial factors in saliva: ontogeny and relation to oral health.
Tenovuo J, Gråhn E, Lehtonen OP, Hyyppä T, Karhuvaara L, Vilja P.J Dent Res. 1987 Feb;66(2):475-9. doi: 10.1177/00220345870660021501.PMID: 3040824
Antimicrobial agents (antibody and non-antibody) present in human saliva protect oral tissues by a variety of mechanisms, such as prevention of bacterial adhesion, agglutination of micro-organisms, and inhibition of multiplication and metabolism. …In the present s …1,267Cite
Lectin binding to formalin-fixed paraffin sections of human endometrium.
Söderström KO.Int J Gynecol Pathol. 1987;6(1):55-65. doi: 10.1097/00004347-198703000-00007.PMID: 31062501,268Cite
Court JP, Martin-Short M, Lees GM.Trop Med Parasitol. 1986 Dec;37(4):375-80.PMID: 35633171,269Cite
Potentialization of the lactoperoxidase system for preservation of raw milk in the tropics.
Aparicio MA, Peralta LM, García HS.Arch Latinoam Nutr. 1986 Dec;36(4):725-33.PMID: 3435217
The antimicrobial ability of the lactoperoxidase system was increased by the addition of larger amounts of the thiocyanate and hydrogen peroxide at levels above those suggested by other authors. …1,270Cite
Greenfield RS, Kiener PA, Chin DP, Curry RC, Spitalny GL.J Leukoc Biol. 1986 Dec;40(6):665-76. doi: 10.1002/jlb.40.6.665.PMID: 3097224
Active MuIFN-gamma was subsequently eluted with ammonium thiocyanate/glycerol (yields of 20-40%). Analysis of the immunopurified interferon by sodium dodecyl sulfate polyacrylamide gel electrophoresis under reducing conditions revealed biologically active bands of about 19 …1,271Cite
Khalil SB, Girgis NI, Mansour NS.J Egypt Soc Parasitol. 1986 Dec;16(2):699-706.PMID: 3097173 No abstract available.1,272Cite
Improved high-affinity monoclonal antibody to iododeoxyuridine.
Vanderlaan M, Watkins B, Thomas C, Dolbeare F, Stanker L.Cytometry. 1986 Nov;7(6):499-507. doi: 10.1002/cyto.990070602.PMID: 3096672 Free article.1,273Cite
Methyl isocyanate subchronic vapor inhalation studies with Fischer 344 rats.
Dodd DE, Fowler EH.Fundam Appl Toxicol. 1986 Oct;7(3):502-22. doi: 10.1016/0272-0590(86)90100-4.PMID: 37811391,274Cite
Clinical evaluation of amoscanate in healthy male volunteers.
Shapiro TA, Were JB, Talalay P, Bueding E, Rocco L, Danso K, Massof R, Green R, Mellits ED, Lietman PS.Am J Trop Med Hyg. 1986 Sep;35(5):945-53. doi: 10.4269/ajtmh.1986.35.945.PMID: 3766854 Clinical Trial.1,275Cite
Oxidation of chloride and thiocyanate by isolated leukocytes.
Thomas EL, Fishman M.J Biol Chem. 1986 Jul 25;261(21):9694-702.PMID: 3015901 Free article.
Peroxidase-catalyzed oxidation of chloride (Cl-) and thiocyanate (SCN-) was studied using neutrophils from human blood and eosinophils and macrophages from rat peritoneal exudates. The aims were to determine whether Cl- or SCN- is preferentially oxidized and whether leukoc …1,276Cite
Kawamoto K, Numa Y, Fujiwara H, Matsumura H, Ikegami H, Kurimoto M, Toriyama K.Gan To Kagaku Ryoho. 1986 Jul;13(7):2346-52.PMID: 3729491 Japanese.1,277Cite
Standardisation of methods for the estimation of thiocyanate and iodine in foodstuff.
Basu SK, Maharda NS, Shukla RK.Indian J Physiol Pharmacol. 1986 Jul-Sep;30(3):241-7.PMID: 3644795
Thiocyanate content in vegetables has been estimated by passing the water extract of vegetables through an alumina column. …The results show the primarily the Cruciferae family vegetables contain higher concentration of thiocyanate….1,278Cite
Sasaki K, Murakami T, Ogino T, Takahashi M, Kawasaki S.Cytometry. 1986 Jul;7(4):391-5. doi: 10.1002/cyto.990070415.PMID: 3089742 Free article.1,279Cite
Virk MS, Issenberg P.Carcinogenesis. 1986 Jun;7(6):867-70. doi: 10.1093/carcin/7.6.867.PMID: 3708751
We compared these results with those obtained with ascorbic acid and thiocyanate. The effect of ascorbic acid was similar to that of syringol. However, thiocyanate increased the amount of NMOR in the stomach and blood 2.7- and 4-fold, respectively. When 2 g of SPD w …1,280Cite
Kallajoki M, Virtanen I, Suominen J.Int J Androl. 1986 Jun;9(3):181-94. doi: 10.1111/j.1365-2605.1986.tb00881.x.PMID: 31004561,281Cite
Skinner MA, Finberg RW, Ertl HC.Cell Immunol. 1986 Jun;100(1):239-46. doi: 10.1016/0008-8749(86)90023-7.PMID: 30912611,282Cite
Fujikawa-Yamamoto K, Miyashita N, Odashima S.Cell Struct Funct. 1986 Jun;11(2):115-24. doi: 10.1247/csf.11.115.PMID: 3089629 Free article.1,283Cite
Schistosoma mansoni: chemotherapy of infections of different ages.
Sabah AA, Fletcher C, Webbe G, Doenhoff MJ.Exp Parasitol. 1986 Jun;61(3):294-303. doi: 10.1016/0014-4894(86)90184-0.PMID: 30861141,284Cite
Nagamune H, Urayama O, Hara Y, Nakao M.J Biochem. 1986 Jun;99(6):1613-24. doi: 10.1093/oxfordjournals.jbchem.a135635.PMID: 3017924 Free article.1,285Cite
Ebert RF.Anal Biochem. 1986 May 1;154(2):431-5. doi: 10.1016/0003-2697(86)90010-2.PMID: 37289621,286Cite
Is thiocyanate peroxidation at equilibrium in vivo?
Pruitt KM, Tenovuo J, Mansson-Rahemtulla B, Harrington P, Baldone DC.Biochim Biophys Acta. 1986 Apr 22;870(3):385-91. doi: 10.1016/0167-4838(86)90245-1.PMID: 3697358
The peroxidase-catalyzed oxidation of SCN- by H2O2 is an important in vivo reaction because it limits the accumulation of toxic H2O2 and provides significant concentrations of the antimicrobial agents, HOSCN and OSCN-. Data presented in this report suggest that the …1,287Cite
Determination of low levels of 4-fluorophenylalanine incorporation into proteins.
Gamcsik MP.Anal Biochem. 1986 Apr;154(1):311-5. doi: 10.1016/0003-2697(86)90530-0.PMID: 37067321,288Cite
Banerjee RK, Datta AG.Mol Cell Biochem. 1986 Apr;70(1):21-9. doi: 10.1007/BF00233801.PMID: 3520291 Review.1,289Cite
Liver damage does not increase the sensitivity of mice to cyanide given acutely.
Rutkowski JV, Roebuck BD, Smith RP.Toxicology. 1986 Mar;38(3):305-14. doi: 10.1016/0300-483x(86)90146-0.PMID: 3952758 Free article.
The major detoxification pathway for cyanide (CN) in many species is a biotransformation to the less toxic thiocyanate (SCN). Hepatic thiosulfate: cyanide sulfurtransferase (rhodanese) is the principal enzyme demonstrating in vitro catalytic activity. …1,290Cite
Induction of DT-diaphorase by anticarcinogenic sulfur compounds in mice.
Benson AM, Barretto PB, Stanley JS.J Natl Cancer Inst. 1986 Mar;76(3):467-73.PMID: 24196221,291Cite
Sobhon P, Wanichanond C, Saitongdee P, Koonchornboon T, Bubphaniroj P, Upatham ES, Puengtomwatanakul S, Sirisinha S.Int J Parasitol. 1986 Feb;16(1):19-26. doi: 10.1016/0020-7519(86)90060-3.PMID: 3699972 No abstract available.1,292Cite
Knasmüller S, Kerklaan P, Mohn GR.Mutat Res. 1986 Feb;164(1):9-17. doi: 10.1016/0165-1161(86)90037-3.PMID: 2419751
The distribution of genotoxic factors in various organs of mice treated orally with nitro-aromatic compounds of actual or potential use as chemotherapeutic (antiprotozoal and anthelminthical) agents was investigated in the DNA-repair host-mediated assay, with mice as host …1,293Cite
Radioiodide transfer across sheep placenta.
Canning JF, Stacey TE, Ward RH, Boyd RD.Am J Physiol. 1986 Jan;250(1 Pt 2):R112-9. doi: 10.1152/ajpregu.1986.250.1.R112.PMID: 3942244
Bidirectional clearance ratios measured in five experiments showed a significant divergence from the value for passive flux predicted from the measured PD, and in four experiments these ratios were also significantly different from unity, this result being incompatible with passi …1,294Cite
[New area of endemic goiter : the northeast Bénoué, (North Cameroon)].
Moulin P, N’Charre C, Hashom A, Boucherat M, Berthezene F.Ann Endocrinol (Paris). 1986;47(6):435-40.PMID: 3827198 French.
The goitrogenic effect of manioc was weak : there was no relationship between the presence of goiter and the amount of ingested manioc. Concentration of thiocyanates in urine was correlated neither with manioc consumption nor with goiter volume. …1,295Cite
Serum protein binding of model acidic drugs in smokers and non-smokers.
Ruiz-Cabello F, Erill S.Int J Clin Pharmacol Res. 1986;6(3):177-9.PMID: 3744622
No differences between the two groups could be detected with regard to the serum protein binding of either drug. Thiocyanate, present in relatively large amounts in the serum of smokers, does not seem to affect the drug-binding properties of serum proteins….1,296Cite
Zahner H, Wegerhof PH.Z Parasitenkd. 1986;72(6):789-804. doi: 10.1007/BF00925099.PMID: 35414241,297Cite
Tenovuo J, Lehtonen OP, Viikari J, Larjava H, Vilja P, Tuohimaa P.J Dent Res. 1986 Jan;65(1):62-6. doi: 10.1177/00220345860650011101.PMID: 3455700
The saliva analysis included the quantitation of total protein, amylase, immunoglobulins (isotypes A, G, and M), and the non-antibody, innate antimicrobial factors (lysozyme, lactoferrin, salivary peroxidase, myeloperoxidase, thiocyanate, and hypothiocyanite). …Th …1,298Cite
Karawajew L, Schlott B.Biomed Biochim Acta. 1986;45(5):K1-3.PMID: 30928141,299Cite
Abdelkhalek MB, Barlet C, Doucet A.J Membr Biol. 1986;89(3):225-40. doi: 10.1007/BF01870666.PMID: 2939249
Microsomal HCO3-ATPase was less sensitive than mitochondrial ATPase to azide, oligomycin, DCCD and thiocyanate, but was more sensitive to filipin and displayed different dependency towards ATP, magnesium and pH. …1,300Cite
Effects of retrograde axonal transport of Ricinus communis agglutinin I on neuroma formation.
Nennesmo I, Kristensson K.Acta Neuropathol. 1986;70(3-4):279-83. doi: 10.1007/BF00686084.PMID: 24294941,301Cite
Preliminary observations on the effect of dietary brussels sprouts on thyroid function.
McMillan M, Spinks EA, Fenwick GR.Hum Toxicol. 1986 Jan;5(1):15-9. doi: 10.1177/096032718600500104.PMID: 2419242
Certain glucosinolates are readily converted into goitrogenic species, notably 5-vinyloxazolidine-2-thione and thiocyanate ion. The effect of dietary Brussels sprouts, a particularly rich source of such glucosinolates, on thyroid function has been examined. …1,302Cite
Antimicrobial factors in whole saliva of human infants.
Tenovuo J, Lehtonen OP, Aaltonen AS, Vilja P, Tuohimaa P.Infect Immun. 1986 Jan;51(1):49-53. doi: 10.1128/iai.51.1.49-53.1986.PMID: 2416690 Free PMC article.
Antimicrobial factors were analyzed in samples of whole saliva from 31 children, aged 0.8 to 3.8 years. …Thus, with the exception of lactoferrin and myeloperoxidase, the nonimmunoglobulin antimicrobial saliva systems studied here seem to be already at the adult le …1,303Cite
Mårtensson J, Kågedal B, Larsson A.Eur J Clin Invest. 1985 Dec;15(6):371-4. doi: 10.1111/j.1365-2362.1985.tb00287.x.PMID: 3938407
She also had an increased excretion of thiosulphate. Low excretion of thiocyanate was observed in both subjects, probably a consequence of a reduced dietary intake of thiocyanate or its precursors. …1,304Cite
Schistosoma mansoni: reduced efficacy of chemotherapy in infected T-cell-deprived mice.
Sabah AA, Fletcher C, Webbe G, Doenhoff MJ.Exp Parasitol. 1985 Dec;60(3):348-54. doi: 10.1016/0014-4894(85)90041-4.PMID: 39354731,305Cite
Kang YH, Carl M, Watson LP, Yaffe L.J Immunol Methods. 1985 Nov 28;84(1-2):177-96. doi: 10.1016/0022-1759(85)90426-0.PMID: 39342841,306Cite
Garlid KD, Beavis AD.J Biol Chem. 1985 Nov 5;260(25):13434-41.PMID: 4055742 Free article.1,307Cite
Gunduz N.Cytometry. 1985 Nov;6(6):597-601. doi: 10.1002/cyto.990060615.PMID: 3933924 Free article.1,308Cite
Antagonism of cyanide poisoning by chlorpromazine and sodium thiosulfate.
Pettersen JC, Cohen SD.Toxicol Appl Pharmacol. 1985 Nov;81(2):265-73. doi: 10.1016/0041-008x(85)90163-2.PMID: 2997948
To investigate the possibility that CPZ enhances thiocyanate formation in ST-pretreated mice, the effects of CPZ on rhodanese activity and the time course of plasma thiocyanate concentrations were investigated. CPZ did not alter hepatic rhodanese kinetics nor did it …1,309Cite
Hypotensive efficacy of a mixed solution of 0.1% sodium nitroprusside and 1% sodium thiosulphate.
Schulz V, Loeschcke G.J Hypertens. 1985 Oct;3(5):485-9.PMID: 40673051,310Cite
Amiconi G, Ascoli F, Concetti A, Matarese M, Verzili D, Brunori M.J Biochem Biophys Methods. 1985 Oct;11(4-5):241-9. doi: 10.1016/0165-022x(85)90006-5.PMID: 4067174
Two methods for the determination of methionine in proteins have been used to estimate the extent of methionine sulfoxide obtained upon exposure of proteins to oxidizing agents. Both methods are based on prior treatment with cyanogen bromide, which attacks methionines (but …1,311Cite
pH-dependent fluoride inhibition of peroxidase activity.
Thibodeau EA, Bowen WH, Marquis RE.J Dent Res. 1985 Oct;64(10):1211-3. doi: 10.1177/00220345850640100601.PMID: 3861651
Fluoride inhibition of lactoperoxidase occurred with all reductants tested, including thiocyanate, iodide, and guaiacol. Fluoride concentrations for 50% inhibition of enzymatic activity with iodide as reductant were: less than 0.05 mM at a pH value of 4.0, 0.3 mM at 5.0, 4 …1,312Cite
The mechanism of calcium uptake by liver microsomes: effect of anions and ionophores.
Chan KM, Koepnick SL.Biochim Biophys Acta. 1985 Sep 10;818(3):291-8. doi: 10.1016/0005-2736(85)90002-1.PMID: 2994726
Under the conditions employed, phosphates, sulfate, chloride, acetate, nitrate, thiocyanate, maleate, succinate and oxalate all stimulated calcium uptake by microsomes, but to different degrees. …1,313Cite
Cyanide, protein and iodine interaction in the performance and metabolism of rats.
Tewe OO, Maner JH.J Environ Pathol Toxicol Oncol. 1985 Sep-Oct;6(1):69-77.PMID: 4067836
Dietary cyanide significantly increased serum and urinary thiocyanate concentration while iodine deficiency caused significant reductions in serum protein bound iodine (PBI). Interactions of protein deficiency and dietary cyanide also significantly reduced serum thiocya …1,314Cite
Chemotherapy of schistosomiasis japonica in China.
Chen MG.Southeast Asian J Trop Med Public Health. 1985 Sep;16(3):473-9.PMID: 3938074 Clinical Trial. No abstract available.1,315Cite
Benson AM, Barretto PB.Cancer Res. 1985 Sep;45(9):4219-23.PMID: 29927731,316Cite
Effects of N-ethylmaleimide on ouabain-insensitive cation fluxes in human red cell ghosts.
Smith DK, Lauf PK.Biochim Biophys Acta. 1985 Aug 27;818(2):251-9. doi: 10.1016/0005-2736(85)90565-6.PMID: 40272481,317Cite
Antimycotic agents: evaluation of some derivatives of 2-thiocyanobenzoic acid.
Pavanetto F, Montanari L, Modena T, Conti B.Farmaco Sci. 1985 Aug;40(8):576-80.PMID: 40433761,318Cite
Meador-Woodruff JH, Yoshino JE, Bigbee JW, Lewis BL, Devries GH.J Neurocytol. 1985 Aug;14(4):619-35. doi: 10.1007/BF01200801.PMID: 3934342 Free article.
The mitogenicity of myelin was reduced 70-80% by these agents whereas the mitogenicity of axolemma was not significantly altered under these conditions. …1,319Cite
Metabolism of mandelonitrile in the rat.
Singh PD, Jackson JR, James SP.Biochem Pharmacol. 1985 Jun 15;34(12):2207-9. doi: 10.1016/0006-2952(85)90420-4.PMID: 4004940 No abstract available.1,320Cite
Porretta GC, Scalzo M, Artico M, Biava M, Panico S, Simonetti N.Farmaco Sci. 1985 Jun;40(6):404-16. doi: 10.1002/chin.198551184.PMID: 3896846
The synthesis and antifungal activities of 1-aryl-4-p-nitrophenylimidazoles and their 2-mercaptoderivatives is reported. Antimicrobial data in comparison with antifungal antibiotic pyrrolnitrin attributed the best activity to 1-p-methoxyphenyl-4-p-nitrophenylimidazole. The …1,321Cite
Pampori NA, Singh G, Srivastava VM.Vet Parasitol. 1985 Jun;18(1):13-9. doi: 10.1016/0304-4017(85)90003-2.PMID: 29962111,322Cite
Effect of thiocyanate levels in milk on thyroid function in iodine deficient subjects.
Dahlberg PA, Bergmark A, Eltom M, Björck L, Claesson O.Am J Clin Nutr. 1985 May;41(5):1010-4. doi: 10.1093/ajcn/41.5.1010.PMID: 3993604 Clinical Trial.
To utilize the antibacterial effect of the lactoperoxidase system to prevent bacterial spoilage of raw milk it is necessary to increase the thiocyanate concentration of the milk. Thiocyanate has, however, a potent antithyroid effect which is enhanced by iodine defic …1,323Cite
Olson BL, McDonald JL Jr, Gleason MJ, Stookey GK, Schemehorn BR, Drook CA, Beiswanger BB, Christen AG.J Dent Res. 1985 May;64(5):826-30. doi: 10.1177/00220345850640050901.PMID: 3858304 Clinical Trial.
Saliva was collected from all subjects and analyzed for acidogenicity and buffer pH as well as for levels of thiocyanate, lactoperoxidase, lysozyme, lactoferrin, and secretory IgA. After 15 weeks of gum usage, saliva was again collected from each subject and the identical …1,324Cite
The antidotal action of thiosulfate following acute nitroprusside infusion in dogs.
Vesey CJ, Krapez JR, Varley JG, Cole PV.Anesthesiology. 1985 Apr;62(4):415-21. doi: 10.1097/00000542-198504000-00008.PMID: 2984962
Within 2 min of the antidote, mean plasma thiocyanate levels (70.3 mumol . l-1) were significantly higher than those of seven control dogs given nitroprusside only (45.9 mumol . l-1, P = 0.002) and plateaued at 153.8 mumol . l-1 within 60 min, while the control values only …1,325Cite
Eltom M, Salih MA, Boström H, Dahlberg PA.Acta Endocrinol (Copenh). 1985 Mar;108(3):356-60. doi: 10.1530/acta.0.1080356.PMID: 3984663
Subjects from rural Darfur also had lower mean serum thyroxine and higher triiodothyronine and thyroid stimulating hormone levels. The mean serum thiocyanate level of 3.2 mg/l in goitrous subjects from rural Darfur was significantly higher than the values of 1.8 ng/ml in g …1,326Cite
Sepe SM, Clark RA.J Immunol. 1985 Mar;134(3):1888-95.PMID: 2981925
Maximum lysis was found with chloride at 10 to 100 mM, although at 1 mM concentrations, iodide, bromide, and thiocyanate were more active than chloride. Fluoride was inactive. Antagonism between halide species was demonstrated in that low concentrations of iodide or bromid …1,327Cite
Höfer M, Künemund A.Biochem J. 1985 Feb 1;225(3):815-9. doi: 10.1042/bj2250815.PMID: 4038875 Free PMC article.
At pH values below 4.5, no TPP+ was taken up, but instead thiocyanate (SCN-) was accumulated, indicating a positive delta psi. The pH-dependent influx of glucosamine followed the pattern of TPP+ accumulation both in the wild-type and in the nystatin-resistant mutant, M67, …1,328Cite
Application of fluorescence polarization to the determination of urinary lysozyme activity.
Miura H.Clin Biochem. 1985 Feb;18(1):40-7. doi: 10.1016/s0009-9120(85)80022-9.PMID: 39212801,329Cite
Andersen KE, Veien NK.Contact Dermatitis. 1985 Feb;12(2):99-103. doi: 10.1111/j.1600-0536.1985.tb01061.x.PMID: 3157538
Routine patch testing with a series of 6 industrial biocides containing methylene-bis-thiocyanate (Cytox 3522), benzisothiazolin-3-one (BIT), chlorocresol (Preventol CMK), 2-n-octyl-4-isothiazolin-3-one (Kathon 893), polyhydroxymethylene monobenzylether (Preventol D2) or 1 …1,330Cite
Thiocyanate feeding with low iodine diet causes chronic iodine retention in thyroids of mice.
van Middlesworth L.Endocrinology. 1985 Feb;116(2):665-70. doi: 10.1210/endo-116-2-665.PMID: 2981672
After 60 days, total thyroidal iodine was 4 times greater than in controls without thiocyanate. The iodinated protein was essentially insoluble at pH 8.0 and was very slowly released from the thyroids; it contained more MIT than DIT and little thyroid hormone. …It is sug …1,331Cite
Prostaglandin E2 transport in rabbit renal basolateral membrane vesicles.
Boumendil-Podevin EF, Podevin RA.Biochim Biophys Acta. 1985 Jan 10;812(1):91-7. doi: 10.1016/0005-2736(85)90525-5.PMID: 3855360
Intravesicular probenecid inhibited the pH gradient-stimulated uptake of prostaglandin E2 but did not affect the pH-stimulated uptake of thiocyanate and acetate which enter membranes via ionic and nonionic diffusion, respectively. …1,332Cite
The immune response to a schistosomacide, amoscanate. II. Cell-mediated immune responses.
Barton BE, Levy DA.J Immunopharmacol. 1985;7(3):373-83. doi: 10.3109/08923978509026482.PMID: 40564131,333Cite
Acrylonitrile inhalation in rats: II. Excretion of thioethers and thiocyanate in urine.
Gut I, Nerudová J, Stiborová A, Kopecký J, Frantík E.J Hyg Epidemiol Microbiol Immunol. 1985;29(1):9-13.PMID: 3989293
The urinary excretion of the main AN metabolites, thioethers (AN-mercapturic acids) and thiocyanate was proportional to the inhaled AN concentration (57, 125, 271 mg X m-3, respectively) in a single exposure for 12 hours, and their mutual ratio was greatly different from t …1,334Cite
The chemotherapy of schistosomiasis.
Archer S.Annu Rev Pharmacol Toxicol. 1985;25:485-508. doi: 10.1146/annurev.pa.25.040185.002413.PMID: 3890709 Review. No abstract available.1,335Cite
Donoghue HD, Perrons CJ, Hudson DE.Arch Oral Biol. 1985;30(7):519-23. doi: 10.1016/0003-9969(85)90051-2.PMID: 38644011,336Cite
Effect of amoscanate derivative CGP 8065 on aminoacyl-tRNA synthetases in Ascaris suum.
Walter RD, Ossikovski E.Mol Biochem Parasitol. 1985 Jan;14(1):23-8. doi: 10.1016/0166-6851(85)90102-1.PMID: 38385731,337Cite
[Effect of drugs on granulocyte motility].
Schmidt D, Morenz J.Allerg Immunol (Leipz). 1985;31(2):67-78.PMID: 3161313 Review. German.
Granulocyte motility is, however, stimulated by ascorbic acid, potassium thiocyanate, levamisole, lithium, and metofenazate….1,338Cite
Csaba G, Török O, Kovács P.Acta Physiol Hung. 1985;66(2):121-6.PMID: 29962951,339Cite
Antibacterial effect of lactoperoxidase and myeloperoxidase against Bacillus cereus.
Tenovuo J, Mäkinen KK, Sievers G.Antimicrob Agents Chemother. 1985 Jan;27(1):96-101. doi: 10.1128/AAC.27.1.96.PMID: 2984983 Free PMC article.
An oral periodontopathic bacterium, Bacillus cereus, was inhibited both by lactoperoxidase (LP) and myeloperoxidase (MP) antimicrobial systems. With the LP-SCN–H2O2 system, the growth inhibition was directly proportional to the amount of OSCN- ions present. …This inhibi …1,340Cite
Traiger GJ, Vyas KP, Hanzlik RP.Chem Biol Interact. 1985 Jan;52(3):335-45. doi: 10.1016/0009-2797(85)90028-6.PMID: 2982508
Ethionamide, sodium diethyldithiocarbamate (Na-DDTC) and S-methyl diethyldithiocarbamate (Me-DDTC), three agents known to undergo metabolism by an S-oxidative pathway and diminish ANIT’s toxicity, inhibited the in vitro enzymatic metabolism of ANIT by rat liver microsomes. …1,341Cite
The murine thymic nurse cell: an isolated thymic microenvironment.
Andrews P, Boyd RL.Eur J Immunol. 1985 Jan;15(1):36-42. doi: 10.1002/eji.1830150108.PMID: 25783991,342Cite
Osmotic water permeability of small intestinal brush-border membranes.
Worman HJ, Field M.J Membr Biol. 1985;87(3):233-9. doi: 10.1007/BF01871223.PMID: 24169341,343Cite
The immune response to a schistosomacide, amoscanate. I. Serum antibody responses.
Barton BE, Levy DA.J Immunopharmacol. 1985;7(3):343-71. doi: 10.3109/08923978509026481.PMID: 24143661,344Cite
Schistosoma haematobium: amoscanate and adult worm ultrastructure.
Leitch B, Probert AJ.Exp Parasitol. 1984 Dec;58(3):278-89. doi: 10.1016/0014-4894(84)90045-6.PMID: 65000011,345Cite
Gonias SL, Oakley AC, Walther PJ, Pizzo SV.Cancer Res. 1984 Dec;44(12 Pt 1):5764-70.PMID: 6209003
Diethyldithiocarbamate, potassium cyanide (KCN), sodium thiocyanate, L-methionine, N-acetyl-L-cysteine, 2-aminoethanethiol, L-cysteine, L-lysine, L-histidine, and L-arginine demonstrated variable capacity to inhibit reaction of cisplatin with protein and to reverse bidenta …1,346Cite
Relationship of the human salivary peroxidase system to oral health.
Tenovuo J, Pruitt KM.J Oral Pathol. 1984 Dec;13(6):573-84. doi: 10.1111/j.1600-0714.1984.tb01459.x.PMID: 6097657
The salivary glands secrete a peroxidase enzyme (salivary peroxidase) as well as the thiocyanate ion (SCN-, derived from diet). The enzyme catalyzes the oxidation of SCN- by hydrogen peroxide (H2O2). …1,347Cite
[Derivatives of 2-thiocyanobenzoic acid with antifungal activity].
Montanari L, Pavanetto F, Modena T, Mazza M.Farmaco Sci. 1984 Nov;39(11):935-44.PMID: 6519264 Italian.1,348Cite
Glutaraldehyde fixation of sodium transport in dog red blood cells.
Parker JC.J Gen Physiol. 1984 Nov;84(5):789-803. doi: 10.1085/jgp.84.5.789.PMID: 6439817 Free PMC article.
The large increase in passive Na flux that occurs when dog red blood cells are caused to shrink is amiloride sensitive and inhibited when Cl is replaced by nitrate or thiocyanate. Activation and deactivation of this transport pathway by manipulation of cell volume is rever …1,349Cite
Properties of the membrane-bound Mg2+-ATPase isolated from Acholeplasma laidlawii.
Chen JW, Sun Q, Hwang F.Biochim Biophys Acta. 1984 Oct 17;777(1):151-4. doi: 10.1016/0005-2736(84)90508-x.PMID: 6148965 No abstract available.1,350Cite
Muramoto K, Kamiya H, Kawauchi H.Anal Biochem. 1984 Sep;141(2):446-50. doi: 10.1016/0003-2697(84)90069-1.PMID: 64372751,351Cite
Pollock JJ, Shoda J, McNamara TF, Cho MI, Campbell A, Iacono VJ.Infect Immun. 1984 Sep;45(3):610-7. doi: 10.1128/iai.45.3.610-617.1984.PMID: 6432696 Free PMC article.
In in vivo studies, hamsters given a combination of NaHCO3, NaCl, and NaSCN were found to have significantly reduced levels of S. mutans on their molar teeth compared with that found in controls or animals exposed to any one of the salts alone or to a combination of chloride and …1,352Cite
Langer P, Földes O, Gschwendtová K.Endocrinol Exp. 1984 Sep;18(3):177-82.PMID: 6092032
The injection of amiodarone (15 mg kg-1) resulted in significant decrease of T3, rT3, 3,3′-T2 and 3,5-T2 excretion and that of thiocyanate (SCN-; 50 mg kg-1) resulted in significantly increased excretion of T4, while that of T3 and 3,5-T2 was significantly decreased. …It …1,353Cite
Onchocerca gibsoni: increase of circulating egg antigen with chemotherapy in bovines.
Forsyth KP, Mitchell GF, Copeman DB.Exp Parasitol. 1984 Aug;58(1):41-55. doi: 10.1016/0014-4894(84)90019-5.PMID: 65476781,354Cite
Hitchens GD, Kell DB.Biochim Biophys Acta. 1984 Jul 27;766(1):222-32. doi: 10.1016/0005-2728(84)90235-4.PMID: 67436501,355Cite
Bolscher BG, Wever R.Biochim Biophys Acta. 1984 Jul 17;788(1):1-10. doi: 10.1016/0167-4838(84)90290-5.PMID: 6331509
From their effects on the binding of cyanide to the enzyme it is concluded that chloride and thiocyanate bind to myeloperoxidase only when the acid/base group is protonated. The pH-dependence of the dissociation constant of the myeloperoxidase-chloride complex obtained fro …1,356Cite
Hutson DH, Logan CJ, Regan PD.Drug Metab Dispos. 1984 Jul-Aug;12(4):523-4.PMID: 6148223 No abstract available.1,357Cite
Toida T, Togawa T, Tanabe S, Imanari T.J Chromatogr. 1984 Jun 8;308:133-41. doi: 10.1016/s0021-9673(01)87540-3.PMID: 6746810
Calibration curves for cyanide and thiocyanate were linear in the range 1-200 pmol and 2-300 pmol, respectively. Clean-up methods for the determination of cyanide and thiocyanate in red cells were also developed. These methods were applied for the determination of c …1,358Cite
Bactericidal and cytotoxic effects of hypothiocyanite-hydrogen peroxide mixtures.
Carlsson J, Edlund MB, Hänström L.Infect Immun. 1984 Jun;44(3):581-6. doi: 10.1128/iai.44.3.581-586.1984.PMID: 6724690 Free PMC article.
Lactoperoxidase catalyzes the oxidation of thiocyanate by hydrogen peroxide into hypothiocyanite, a reaction which can protect bacterial and mammalian cells from killing by hydrogen peroxide. The present study demonstrates, however, that lactoperoxidase in the presence of …1,359Cite
Evaluation of selected anthelmintic compounds for activity against Opisthorchis viverrini.
Tawatsin A, Sirisinha S, Vajrasthira S, Bunnag D, Harinasuta T.Tropenmed Parasitol. 1984 Jun;35(2):85-90.PMID: 6464190
In vitro and in vivo experiments were employed in the screening of potential anthelmintic agents against Opisthorchis viverrini infection in hamsters. A few selected groups of compounds tested included those that are commercially available as well as those that are still b …1,360Cite
Protein-enhanced fluorescein chemiluminescence used in an immunoassay for rubella antibody in serum.
Shapiro R, Chan J, Pierson A, Vaccaro K, Quick J.Clin Chem. 1984 Jun;30(6):889-93.PMID: 64268211,361Cite
Walter RD, Albiez EJ.Tropenmed Parasitol. 1984 Jun;35(2):78-80.PMID: 60875211,362Cite
Zaĭtsev KT, Banin VV.Arkh Anat Gistol Embriol. 1984 May;86(5):92-7.PMID: 6431948 Russian. No abstract available.1,363Cite
Thiocyanates and iodine in endemic goiter in Italy.
Costa A, De Filippis V, Barbeni M, Bestagno M, Giraudi G, Grillo C.J Endocrinol Invest. 1984 Apr;7(2):103-10. doi: 10.1007/BF03348398.PMID: 6725867
Urinary iodine (I) and serum and urinary thiocyanates (SCN-) were determined in sample groups from 12 areas of endemic goiter in Italy. …We have found no correlation between thiocyanate itself and goiter….1,364Cite
Traiger GJ, Vyas KP, Hanzlik RP.Toxicol Appl Pharmacol. 1984 Mar 15;72(3):504-12. doi: 10.1016/0041-008x(84)90127-3.PMID: 6324415
Pretreatment with phenobarbital which stimulates toxicity in vivo increased urinary [35S]sulfate excretion 300% in the first 12 hr. Thus, this study shows that agents which sensitize or protect rats from the toxic effects of ANIT, correspondingly stimulate or inhibit the o …1,365Cite
Endemic infantile hypothyroidism in a severe endemic goitre area of central Africa.
Vanderpas J, Bourdoux P, Lagasse R, Rivera M, Dramaix M, Lody D, Nelson G, Delange F, Ermans AM, Thilly CH.Clin Endocrinol (Oxf). 1984 Mar;20(3):327-40. doi: 10.1111/j.1365-2265.1984.tb00089.x.PMID: 6723080
Thiocyanate concentration was high (133 +/- 7 mumol/l) in the mothers’ serum but low in the mothers’ milk (57 +/- 3 mumol/l) (P less than 0.001). …Thiocyanate concentration was high (133 +or- 7 umol/1) in the mothers’ serum but low in the mothers’ milk (57 +or- 3 …1,366Cite
Devriese LA, Dutta GN.J Vet Pharmacol Ther. 1984 Mar;7(1):49-53. doi: 10.1111/j.1365-2885.1984.tb00878.x.PMID: 67081661,367Cite
Intake of thiocyanate by way of milk and its possible effect on thyroid function.
Dahlberg PA, Bergmark A, Björck L, Bruce A, Hambraeus L, Claesson O.Am J Clin Nutr. 1984 Mar;39(3):416-20. doi: 10.1093/ajcn/39.3.416.PMID: 6546468
To make such an activation efficient the thiocyanate concentration has to be increased. Since, however, thiocyanate has a potent antithyroid effect, thyroid function has been studied in 37 healthy individuals during 12 wk of daily intake of 8 mg thiocyanate b …1,368Cite
Effects of amoscanate on the utilization of glucose by Brugia pahangi and Litomosoides carinii.
Nelson NF, Saz HJ.J Parasitol. 1984 Feb;70(1):194-6.PMID: 6737169 No abstract available.1,369Cite
Pyocin R1 inhibits active transport in Pseudomonas aeruginosa and depolarizes membrane potential.
Uratani Y, Hoshino T.J Bacteriol. 1984 Feb;157(2):632-6. doi: 10.1128/jb.157.2.632-636.1984.PMID: 6420392 Free PMC article.
In addition, a passive inflow of [14C]thiocyanate anion, a probe of membrane potential, was induced by pyocin R1, showing a depolarization of the cytoplasmic membrane. …1,370Cite
Mickelson MN, Anderson AJ.Appl Environ Microbiol. 1984 Feb;47(2):338-42. doi: 10.1128/aem.47.2.338-342.1984.PMID: 6370135 Free PMC article.
Cystine reduction in Streptococcus agalactiae, resulting in sulfhydryl formation, may account for antagonism of the antibacterial effect of lactoperoxidase-thiocyanate-hydrogen peroxide when cystine is present in excess of the amount needed for maximum growth. …The infor …1,371Cite
Mechanism of iodide-dependent catalatic activity of thyroid peroxidase and lactoperoxidase.
Magnusson RP, Taurog A, Dorris ML.J Biol Chem. 1984 Jan 10;259(1):197-205.PMID: 6706930 Free article.
To elucidate the mechanism of the iodide-dependent catalatic activity, the effects of various agents were investigated. The major observations may be summarized as follows: 1) The catalatic activity was inhibited in the presence of an iodine acceptor such as tyrosine. 2) T …1,372Cite
Heinrikson RL, Meredith SC.Anal Biochem. 1984 Jan;136(1):65-74. doi: 10.1016/0003-2697(84)90307-5.PMID: 67118151,373Cite
Tenovuo J, Larjava H.Arch Oral Biol. 1984;29(6):445-51. doi: 10.1016/0003-9969(84)90025-6.PMID: 6589987
The hypothiocyanite ion (OSCN-) is the principal oxidation product of the salivary peroxidase-thiocyanate (SCN-)-hydrogen peroxide antimicrobial system. Supplementation of human saliva in vitro and in vivo with low amounts (less than 1.0 mM) of hydrogen peroxide inc …1,374Cite
Studies of mammalian ornithine decarboxylase using a monoclonal antibody.
Pegg AE, Seely JE, Persson L, Herlyn M, Ponsell K, O’Brien TG.Biochem J. 1984 Jan 1;217(1):123-8. doi: 10.1042/bj2170123.PMID: 6421279 Free PMC article.
The active enzyme could then be eluted in a highly purified form by 1.0M-sodium thiocyanate. The monoclonal antibody could also be used to precipitate labelled ornithine decarboxylase from homogenates of kidneys from androgen-treated mice given [35S]methionine. …1,375Cite
Maintenance of platelet viability after platelet-labeling with fluorescein isothiocyanate.
Klaverkamp J, Völkl KP.Haemostasis. 1984;14(4):337-46. doi: 10.1159/000215085.PMID: 62388811,376Cite
Tenovuo J, Mäkinen KK, Paunio K.Proc Finn Dent Soc. 1984;80(1):28-34.PMID: 6201845 No abstract available.1,377Cite
Gel protein stains: glycoproteins.
Gander JE.Methods Enzymol. 1984;104:447-51. doi: 10.1016/s0076-6879(84)04112-4.PMID: 6201699 No abstract available.1,378Cite
Fluorescein conjugates as indicators of subcellular pH. A critical evaluation.
Geisow MJ.Exp Cell Res. 1984 Jan;150(1):29-35. doi: 10.1016/0014-4827(84)90698-0.PMID: 61981891,379Cite
Comparison of salivary peroxidase system components in caries-free and caries-active naval recruits.
Lamberts BL, Pruitt KM, Pederson ED, Golding MP.Caries Res. 1984;18(6):488-94. doi: 10.1159/000260809.PMID: 6091882 No abstract available.1,380Cite
Reddy AB, Rao UR, Chandrashekar R, Shrivastava R, Subrahmanyam D.Tropenmed Parasitol. 1983 Dec;34(4):259-62.PMID: 66658681,381Cite
Early effects of high-dosed absorbable amoscanate on rat brain.
Krinke G, Graepel P, Krueger L, Thomann P.Toxicol Lett. 1983 Dec;19(3):261-6. doi: 10.1016/0378-4274(83)90128-5.PMID: 66588391,382Cite
Tycko B, Keith CH, Maxfield FR.J Cell Biol. 1983 Dec;97(6):1762-76. doi: 10.1083/jcb.97.6.1762.PMID: 6315742 Free PMC article.1,383Cite
Greene LK, Grenan MM, Davidson DE Jr, Jones DH, Shedd TR.Am J Trop Med Hyg. 1983 Nov;32(6):1356-63. doi: 10.4269/ajtmh.1983.32.1356.PMID: 66507361,384Cite
Zhou GX.Zhonghua Nei Ke Za Zhi. 1983 Oct;22(10):634-5.PMID: 6673935 Chinese. No abstract available.1,385Cite
A mouthrinse which optimizes in vivo generation of hypothiocyanite.
Mansson-Rahemtulla B, Pruitt KM, Tenovuo J, Le TM.J Dent Res. 1983 Oct;62(10):1062-6. doi: 10.1177/00220345830620101101.PMID: 6578235
We report here the properties of a mouthrinse which enhances one of the natural defense factors in human saliva, the salivary peroxidase system. Concentrations of the antimicrobial agent, the hypothiocyanite (OSCN-) ion, can be increased in vivo to bacteriostatic levels by …1,386Cite
Efficacy of amoscanate against experimental schistosomal infections in monkeys.
Crawford KA, Asch HL, Bruce JI, Bueding E, Smith ER.Am J Trop Med Hyg. 1983 Sep;32(5):1055-64. doi: 10.4269/ajtmh.1983.32.1055.PMID: 66250611,387Cite
Functional properties of plasmids in lactic streptococci.
McKay LL.Antonie Van Leeuwenhoek. 1983 Sep;49(3):259-74. doi: 10.1007/BF00399502.PMID: 6312881 Review.
In this category would be sensitivity to agglutinins, sensitivity to the lactoperoxidase-thiocyanate-hydrogen peroxide inhibitory system, arginine hydrolysis, and slime production. …1,388Cite
[Assay of organic bases in pharmaceutical preparations using cobalt thiocyanate].
Lemli J, Knockaert I.Pharm Weekbl Sci. 1983 Aug 26;5(4):142-4. doi: 10.1007/BF01961470.PMID: 6622207 French.
A rapid and simple colorimetric method is presented for the estimation of organic bases in pharmaceutical preparations. Solid cobalt thiocyanate reagent is used. Many bases form blue coloured ion pairs soluble in dichloromethane….1,389Cite
Periyasamy SM, Huang WH, Askari A.J Biol Chem. 1983 Aug 25;258(16):9878-85.PMID: 6309787 Free article.1,390Cite
Hershman JM, Due DT, Sharp B, My L, Kent JR, Binh LN, Reed AW, Phuc LD, Van Herle AJ, Thai NA, Troung TX, Van NV, Sugawara M, Pekary AE.J Clin Endocrinol Metab. 1983 Aug;57(2):243-9. doi: 10.1210/jcem-57-2-243.PMID: 6863473
The urinary iodine concentration was low in both goitrous regions, and urinary thiocyanate was increased in Dich Giao, reflecting the ingestion of cassava. For all regions combined, there was a direct correlation between serum TSH and T3 and between serum TSH and Tg. …In …1,391Cite
[Side effects on the nervous system caused by nithiocyamine. Clinical observation of 47 cases].
Wu LS, Li F.Zhonghua Nei Ke Za Zhi. 1983 Aug;22(8):477-9.PMID: 6653210 Chinese. No abstract available.1,392Cite
The salivary lactoperoxidase system in caries-resistant and -susceptible adults.
Mandel ID, Behrman J, Levy R, Weinstein D.J Dent Res. 1983 Aug;62(8):922-5. doi: 10.1177/00220345830620081501.PMID: 6575042
In a comparative study of caries-resistant and -susceptible adults, no significant differences were found in the concentrations of lactoperoxidase, thiocyanate, and pre-formed hypothiocyanite in parotid and submandibular saliva, or in hypothiocyanite formed in expectorated …1,393Cite
Hymenolepis diminuta: effects of amoscanate on energy metabolism and ultrastructure.
Nelson NF, Saz HJ.Exp Parasitol. 1983 Aug;56(1):55-69. doi: 10.1016/0014-4894(83)90096-6.PMID: 64096591,394Cite
[Efficacy of amoscanate derivatives in experimental schistosomiasis].
Yue WJ, Shao BR, Pan QR, You JQ, Mei JY.Yao Xue Xue Bao. 1983 Jul;18(7):541-4.PMID: 6659959 Chinese. No abstract available.1,395Cite
Effects of thiosulfate on cyanide pharmacokinetics in dogs.
Sylvester DM, Hayton WL, Morgan RL, Way JL.Toxicol Appl Pharmacol. 1983 Jun 30;69(2):265-71. doi: 10.1016/0041-008x(83)90307-1.PMID: 6868088
A compartmental model for thiocyanate, the major metabolite of cyanide, was developed from plasma concentrations determined at various times after iv administration of thiocyanate; sodium thiosulfate did not alter thiocyanate-model parameters. The model for …1,396Cite
Kurtz MJ, Billings M, Koh T, Olander G, Tyner T, Weaver B, Stone L.Clin Chem. 1983 Jun;29(6):1015-9.PMID: 64060921,397Cite
[Potentiation of pentobarbital hypnosis by nitrodiphenylaminoisothiocyanate].
Tu ZG, Quan YZ.Zhongguo Yao Li Xue Bao. 1983 Jun;4(2):87-92.PMID: 6225309 Free article. Chinese. No abstract available.1,398Cite
Is Cytox 3522 (10% methylene-bis-thiocyanate) a human skin sensitizer?
Andersen KE, Hamann K.Contact Dermatitis. 1983 May;9(3):186-9. doi: 10.1111/j.1600-0536.1983.tb04355.x.PMID: 6861481
Methylene-bis-thiocyanate is an antimicrobial agent in Cytox 3522 (American Cyanamid Corporation) and Nalco 206 (Nalco Chemical Company). …1,399Cite
Passive calcium movements in dog red blood cells: anion effects.
Parker JC.Am J Physiol. 1983 May;244(5):C318-23. doi: 10.1152/ajpcell.1983.244.5.C318.PMID: 6846522
Calcium influx in dog red blood cells was stimulated by replacing chloride in the medium with nitrate or thiocyanate. These anion effects were due to stimulation of a sodium-dependent calcium pathway, because calcium influx in the presence of nitrate or thiocyanate …1,400Cite
Cell surface structures required for B-cell activation with haptenated syngeneic cells.
Ramos T.Scand J Immunol. 1983 May;17(5):411-7. doi: 10.1111/j.1365-3083.1983.tb00807.x.
George S, Schenck JR.Anal Biochem. 1983 Apr 15;130(2):416-9. doi: 10.1016/0003-2697(83)90609-7.PMID: 6869829 No abstract available.1,402Cite
Peroxidase activity and thiocyanate accumulation in salivary glands.
Bratt P, Paul KG.Experientia. 1983 Apr 15;39(4):386-7. doi: 10.1007/BF01963138.PMID: 6832317
The content of SCN- in a salivary gland does not mirror the gland’s participation in the peroxidase-mediated antimicrobial mechanism….1,403Cite
Carlsson J, Iwami Y, Yamada T.Infect Immun. 1983 Apr;40(1):70-80. doi: 10.1128/iai.40.1.70-80.1983.PMID: 6832837 Free PMC article.
Acid production, oxygen uptake, and, consequently, hydrogen peroxide excretion were inhibited in all the strains by lactoperoxidase-thiocyanate-hydrogen peroxide. S. sanguis and S. mitis had a higher capacity than S. mutans and S. salivarius to recover from this inhibition …1,404Cite
Metabolism of some naturally occurring isothiocyanates in the rat.
Mennicke WH, Görler K, Krumbiegel G.Xenobiotica. 1983 Apr;13(4):203-7. doi: 10.3109/00498258309052256.PMID: 66241351,405Cite
Phenithionate in schistosomiasis japonica. Preliminary report of 463 cases.
Liu YH, Wang QN, Wang XG, Zhan QD, Lu XE, Ma YX, Liu ZL.Chin Med J (Engl). 1983 Apr;96(4):269-74.PMID: 6413140 No abstract available.1,406Cite
Proton translocation during denitrification by a nitrifying–denitrifying Alcaligenes sp.
Castignetti D, Hollocher TC.Antonie Van Leeuwenhoek. 1983 Apr;49(1):61-8. doi: 10.1007/BF00457880.PMID: 6311094
None of the three permeant ions employed with the Alcaligenes sp. (valinomycin-K+, thiocyanate and triphenylmethylphosphonium) was ideal for all purposes. Thiocyanate provided highest ratios for O2 but abolished the oxidant pulse response for nitrate and N2O. …1,407Cite
Incorporation of bacteriorhodopsin into large unilamellar liposomes by reverse phase evaporation.
Rigaud JL, Bluzat A, Buschlen S.Biochem Biophys Res Commun. 1983 Mar 16;111(2):373-82. doi: 10.1016/0006-291x(83)90316-9.PMID: 6838566
In the absence of the latter, a light-independent transmembrane potential of about 60 mV was measured from thiocyanate distribution. In the presence of valinomycin, this transmembrane electrical potential was abolished and then a light-dependent transmembrane pH gradient o …1,408Cite
[Electron microscopic studies on the effect of nithiocyamine on Schistosoma japonica].
Yu HZ, Lu M, Zhao KB, Wang P.Yao Xue Xue Bao. 1983 Mar;18(3):169-73.PMID: 6880755 Chinese. No abstract available.1,409Cite
Action of thiocyanate on pH gradient formation by gastric microsomal vesicles.
Reenstra WW, Forte JG.Am J Physiol. 1983 Mar;244(3):G308-13. doi: 10.1152/ajpgi.1983.244.3.G308.PMID: 6829771
The effects of thiocyanate anion (SCN-) on proton accumulation and ATP hydrolysis by hog gastric microsomal vesicles have been investigated. …1,410Cite
Purdy MA, Tenovuo J, Pruitt KM, White WE Jr.Infect Immun. 1983 Mar;39(3):1187-95. doi: 10.1128/iai.39.3.1187-1195.1983.PMID: 6341231 Free PMC article.
The lactoperoxidase-thiocyanate-hydrogen peroxide system was found to have both bacteriostatic and bactericidal activities against strains of Salmonella typhimurium. …This acid production was inhibited by the lactoperoxidase-thiocyanate-hydrogen peroxide system, a …1,411Cite
Inhibition of Streptococcus mutans by the lactoperoxidase antimicrobial system.
Thomas EL, Pera KA, Smith KW, Chwang AK.Infect Immun. 1983 Feb;39(2):767-78. doi: 10.1128/iai.39.2.767-778.1983.PMID: 6832819 Free PMC article.
Inhibition of bacterial metabolism by the lactoperoxidase (LP)-hydrogen peroxide (H2O2)-thiocyanate system was studied with representatives of serotypes a through g of Streptococcus mutans. …All strains were inhibited when incubated with LP, thiocyanate, and added …1,412Cite
Liu CX, Huang WT, Liu RF, Ye GZ, Xiang JJ, Zhang ZL, Hu JC.Yao Xue Xue Bao. 1983 Feb;18(2):86-9.PMID: 6613597 Chinese. No abstract available.1,413Cite
Peroxidase-thiocyanate-peroxide antibacterial system does not damage DNA.
White WE Jr, Pruitt KM, Mansson-Rahemtulla B.Antimicrob Agents Chemother. 1983 Feb;23(2):267-72. doi: 10.1128/AAC.23.2.267.PMID: 6340603 Free PMC article.
This finding has led to the suggestion that antibacterial properties of human saliva might be enhanced in vivo by appropriate supplements which elevate OSCN(-) concentrations. Since DNA is sensitive to oxidizing agents (hydrogen peroxide attacks nucleosides), high concentr …1,414Cite
Lactoperoxidase and thiocyanate protect cultured mammalian cells against hydrogen peroxide toxicity.
Hänström L, Johansson A, Carlsson J.Med Biol. 1983;61(5):268-74.PMID: 6686988
In the presence of lactoperoxidase and thiocyanate the cells were protected from the toxic effects of hydrogen peroxide as disclosed by their capacity to proliferate and exclude trypan blue. The rate of acid production of the cells in the presence of glucose was inhibited, …1,415Cite
Pruitt KM, Mansson-Rahemtulla B, Tenovuo J.Arch Oral Biol. 1983;28(6):517-25. doi: 10.1016/0003-9969(83)90184-x.PMID: 6578767
Human whole saliva contains the hypothiocyanite ion (OSCN-) which is the principal antimicrobial product of the salivary peroxidase system. The peroxidase system requires a source of peroxide in order to produce OSCN- and in the human mouth this source has been assumed to …1,416Cite
García de Torres G, Römer KG, Torres Alanis O, Freundt KJ.Drug Chem Toxicol. 1983;6(4):317-28. doi: 10.3109/01480548309082713.PMID: 64131901,417Cite
Holecek V, Kopecký J.Czech Med. 1983;6(2):116-21.PMID: 6409562
It appears, at the same time, however, that massive doses of acrylonitrile may endanger the biological system by depletion of large quantities of glutathione a schematic chart of the metabolic exchanges of acrylonitrile was suggested demonstrating that a part of the total amount …1,418Cite
Pollock JJ, Goodman H, Elsey PK, Iacono VJ.Arch Oral Biol. 1983;28(9):865-71. doi: 10.1016/0003-9969(83)90045-6.PMID: 6314951
At apparent sub-lytic concentrations of NaHCO3, lysis was achieved by adding an appropriate concentration of one of NaSCN, NaCl or NaF to the lysozyme-protease-damaged cells. Thiocyanate proved to be most effective among the anions requiring lower concentrations to elicit …1,419Cite
Rapid purification of fluorescent enzymes by ultrafiltration.
Benjaminson MA, Satyanarayana T.Prep Biochem. 1983;13(1):41-4. doi: 10.1080/00327488308068733.PMID: 61901591,420Cite
Ethanol effects on synaptic glutamate receptor function and on membrane lipid organization.
Michaelis EK, Chang HH, Roy S, McFaul JA, Zimbrick JD.Pharmacol Biochem Behav. 1983;18 Suppl 1:1-6. doi: 10.1016/0091-3057(83)90138-7.PMID: 6138770
The function of the L-glutamate receptor-ion channel complex in the presence of ethanol was also determined by measuring the changes in thiocyanate (SCN-) influx brought about by L-glutamate or ethanol. A low concentration of ethanol (9.4 mM) diminished the L-glutamate-ind …1,421Cite
Kitagawa S, Takaku F.Biochim Biophys Acta. 1982 Dec 17;719(3):589-98. doi: 10.1016/0304-4165(82)90249-5.PMID: 6295508
F-Met-Phe-induced O2- production was markedly potentiated not only by microtubule-disrupting agents, including colchicine, vincristine, vinblastine, nocodazole, podophyllotoxin and griseofulvin, but also deuterium oxide (2H2O), which is proposed to stabilize microtubules, …1,422Cite
Doherty PA, Smith RP, Ferm VH.J Pharmacol Exp Ther. 1982 Dec;223(3):635-41.PMID: 7143230 No abstract available.1,423Cite
Bacteriolysis of Streptococcus mutans GS5 by lysozyme, proteases, and sodium thiocyanate.
Wilkens TJ, Goodman H, MacKay BJ, Iacono VJ, Pollock JJ.Infect Immun. 1982 Dec;38(3):1172-80. doi: 10.1128/iai.38.3.1172-1180.1982.PMID: 6759407 Free PMC article.
Bacteriolysis was achieved by sequential treatment of the cells with either hen egg white lysozyme and sodium thiocyanate or a combination of hen egg white lysozyme and a proteolytic enzyme followed by addition of the thiocyanate. In the absence of sodium thiocya …1,424Cite
Thomas EL, Jefferson MM, Grisham MB.Biochemistry. 1982 Nov 23;21(24):6299-308. doi: 10.1021/bi00267a040.PMID: 6295461
Initiation of the reaction required HOCl, and oxidized forms of bromide, iodide, or thiocyanate did not substitute. Inhibitors of incorporation fell into three classes. First, ammonia or amines competed with the labeled amine for reaction with HOCl, so that larger amounts …1,425Cite
Cyanide toxicity of sodium nitroprusside in therapeutic use with and without sodium thiosulphate.
Schulz V, Gross R, Pasch T, Busse J, Loeschcke G.Klin Wochenschr. 1982 Nov 15;60(22):1393-400. doi: 10.1007/BF01716244.PMID: 7176461
The concentrations of cyanide and of thiocyanate in the blood of all patients were measured. In seven of the patients the level of thiosulphate was also measured. …1,426Cite
Ahmad F, Bigelow CC.J Biol Chem. 1982 Nov 10;257(21):12935-8.PMID: 7130187 Free article.
The denaturation of ribonuclease A, lysozyme alpha-lactalbumin, and myoglobin by urea, guanidine hydrochloride, and guanidine thiocyanate has been followed with the use of difference spectral measurements. The free energy of stabilization (delta GH2OD) has been determined …1,427Cite
Neuropathology of the antischistosomal agent amoscanate administered in high oral doses to rats.
Clark AW, Kiel SM, Parhad IM.Neurotoxicology. 1982 Nov;3(3):1-11.PMID: 68917571,428Cite
The use of inhibitors in the study of glycosidases.
Lalégerie P, Legler G, Yon JM.Biochimie. 1982 Nov-Dec;64(11-12):977-1000. doi: 10.1016/s0300-9084(82)80379-9.PMID: 6819005 Review.1,429Cite
Reddy BS, Batzinger RP, Molineaux CJ, Bueding E.Antimicrob Agents Chemother. 1982 Oct;22(4):707-8. doi: 10.1128/AAC.22.4.707.PMID: 7181482 Free PMC article.1,430Cite
Liu YH.Zhonghua Nei Ke Za Zhi. 1982 Oct;21(10):609-13.PMID: 7151549 Chinese. No abstract available.1,431Cite
Effect of oxygen on the antagonism of cyanide intoxication–cytochrome oxidase, in vivo.
Isom GE, Burrows GE, Way JL.Toxicol Appl Pharmacol. 1982 Sep 15;65(2):250-6. doi: 10.1016/0041-008x(82)90007-2.PMID: 6294919 No abstract available.1,432Cite
Cho MI, Holt SC, Iacono VJ, Pollock JJ.J Bacteriol. 1982 Sep;151(3):1498-507. doi: 10.1128/jb.151.3.1498-1507.1982.PMID: 7107557 Free PMC article.
The effects of hen egg white lysozyme and the inorganic salt sodium thiocyanate on the integrity of Streptococcus mutans BHT were studied by transmission electron microscopy. …1,433Cite
Bisby RH, Cundall RB, Movassaghi S, Adams GE, Posener ML, Wardman P.Int J Radiat Biol Relat Stud Phys Chem Med. 1982 Aug;42(2):163-71. doi: 10.1080/09553008214551031.PMID: 6982249 No abstract available.1,434Cite
Tenovuo J, Pruitt KM, Thomas EL.J Dent Res. 1982 Aug;61(8):982-5. doi: 10.1177/00220345820610081301.PMID: 6955343
The antimicrobial oxidizing agent hypothiocyanite ion (OSCN-) was measured in resting (drooling) and stimulated (expectorated) whole saliva. …Assuming that the antimicrobial activity of the salivary peroxidase system is proportional to OSCN- concentration, this sy …1,435Cite
Quan YZ, Huang WY, Zhou QX, Li YZ.Yao Xue Xue Bao. 1982 Jul;17(7):481-6.PMID: 7180477 Chinese. No abstract available.1,436Cite
Sawata A, Kume K, Nakase Y.Am J Vet Res. 1982 Jul;43(7):1311-4.PMID: 6808871
However, when the organisms were treated with potassium thiocyanate (KSCN) and/or sonication, activity occurred not only against GA-fixed chicken RBC, but also against GA-fixed RBC of various animal species. …1,437Cite
Kinetics of hypothiocyanite production during peroxidase-catalyzed oxidation of thiocyanate.
Pruitt KM, Tenovuo J.Biochim Biophys Acta. 1982 Jun 4;704(2):204-14. doi: 10.1016/0167-4838(82)90147-9.PMID: 7104367
We report here a kinetic study of the generation of hypothiocyanite (OSCN-), a product of lactoperoxidase-catalyzed oxidation of thiocyanate ion. Previous studies have measured OSCN- by reactions involving the oxidation of sulfhydryl compounds. …The second-order rate con …1,438Cite
Morphological alterations of Schistosoma japonicum associated with the administration of amoscanate.
Irie Y, Yasuraoka K.Jpn J Exp Med. 1982 Jun;52(3):139-48.PMID: 71318581,439Cite
Courtin F, Deme D, Virion A, Michot JL, Pommier J, Nunez J.Eur J Biochem. 1982 Jun;124(3):603-9. doi: 10.1111/j.1432-1033.1982.tb06637.x.PMID: 7106111 Free article. No abstract available.1,440Cite
Membrane potential of Plasmodium-infected erythrocytes.
Mikkelsen RB, Tanabe K, Wallach DF.J Cell Biol. 1982 Jun;93(3):685-9. doi: 10.1083/jcb.93.3.685.PMID: 6288730 Free PMC article.
The membrane potential (Em) of normal and Plasmodium chabaudi-infected rat erythrocytes was determined from the transmembrane distributions of the lipophilic anion, thiocyanate (SCN), and cation, triphenylmethylphosphonium (TPMP). The SCN- and TPMP-measured Em of normal er …1,441Cite
Nandi J, Ray TK.Arch Biochem Biophys. 1982 Jun;216(1):259-71. doi: 10.1016/0003-9861(82)90211-9.PMID: 6285831 No abstract available.1,442Cite
Sawada T, Rimler RB, Rhoades KR.J Clin Microbiol. 1982 May;15(5):752-6. doi: 10.1128/jcm.15.5.752-756.1982.PMID: 6808010 Free PMC article.
GA-SRBC were stable for at least 6 months. Heat extract or potassium thiocyanate extract antigens of Pasteurella strains could be adsorbed onto GA-SRBC or tanned GA-SRBC, respectively. The indirect hemagglutination test reaction was capsular group specific with heat extrac …1,443Cite
Lowry BS, Vega FG Jr, Hedlund KW.Am J Clin Pathol. 1982 May;77(5):601-5. doi: 10.1093/ajcp/77.5.601.PMID: 61772361,444Cite
Macrophage interactions with antibodies and soluble immune complexes.
Leslie RG.Immunobiology. 1982 Apr;161(3-4):322-33. doi: 10.1016/S0171-2985(82)80089-2.PMID: 6212532 Review.1,445Cite
Lactoperoxidase-catalyzed oxidation of thiocyanate: polarographic study of the oxidation products.
Pruitt KM, Tenovuo J, Andrews RW, McKane T.Biochemistry. 1982 Feb 2;21(3):562-7. doi: 10.1021/bi00532a023.PMID: 7066307
The lactoperoxidase-catalyzed oxidation of thiocyanate (SCN-) was studied by two different polarographic techniques: direct current polarography and linear sweep voltammetry. …This type of reaction can explain why, in solutions which already contain OSCN- (e.g., in saliv …1,446Cite
Tenovuo J, Moldoveanu Z, Mestecky J, Pruitt KM, Rahemtulla BM.J Immunol. 1982 Feb;128(2):726-31.PMID: 7054295
The antimicrobial effect of the lactoperoxidase (LPO) system (enzyme with the thiocyanate ion and hydrogen peroxide) on Streptococcus mutans NCTC 10449 (serotype c) was significantly enhanced when the system was combined with secretory IgA. …None of the immunoglob …1,447Cite
[Blood concentrations and anti-Borrelia anserina activity of erythromycin salts in birds].
Stoianova-Zaĭkova L, Doneva M.Vet Med Nauki. 1982;19(1):97-103.PMID: 7112926 Bulgarian.
Tested was comparatively the antispirochaetal activity of erythromycin asparaginate (EA), thiocyanate (ET), and lactate (EL) in a total of 314 chickens, pullets and cockerels artificially infected with Borrelia anserina (strains Surnevo and Pamoukchii). …1,448Cite
[Determination of the iodine content in food products using the nitrite-rhodanide method].
Proskuriakova GV, Eremin IuN.Vopr Pitan. 1982 Jan-Feb;(1):59-61.PMID: 7072183 Russian.1,449Cite
Thermal effect of photolysis in 203Hg, 35S and 131I labeled mercury (II) iodide thiocyanate powders.
Takei K, Hagiwara H, Nakamura S.Radioisotopes. 1982 Jan;31(1):6-10. doi: 10.3769/radioisotopes.31.6.PMID: 7071390
203Hg, 35S or 131I labeled mercury (II) iodide thiocyanate (HgISCN) powders were prepared, respectively. When the powders were exposed to sunlight, some parts of the crystals of the powders were decomposed and the decomposed atoms diffused toward crystal surface. …1,450Cite
Ingram LO.J Bacteriol. 1982 Jan;149(1):166-72. doi: 10.1128/jb.149.1.166-172.1982.PMID: 7033206 Free PMC article.
Growth of Escherichia coli in the presence of ethanol and chaotropic salts resulted in the synthesis of lipids containing elevated levels of unsaturated fatty acids analogous to the effect of a reduction in growth temperature. Both ethanol and chaotropic agents acted at th …1,451Cite
Lactoperoxidase and thiocyanate protect bacteria from hydrogen peroxide.
Adamson M, Carlsson J.Infect Immun. 1982 Jan;35(1):20-4. doi: 10.1128/iai.35.1.20-24.1982.PMID: 7033135 Free PMC article.
Lactoperoxidase and thiocyanate were shown to protect Escherichia coli and three oral streptococcal species from the bactericidal effect of hydrogen peroxide under aerobic conditions. …The results demonstrate the effectiveness of lactoperoxidase and thiocyanate in …1,452Cite
Limiting factors for the generation of hypothiocyanite ion, an antimicrobial agent, in human saliva.
Pruitt KM, Tenovuo J, Fleming W, Adamson M.Caries Res. 1982;16(4):315-23. doi: 10.1159/000260614.PMID: 6956446 No abstract available.1,453Cite
Maloney PC, Hansen FC 3rd.J Membr Biol. 1982;66(1):63-75. doi: 10.1007/BF01868482.PMID: 62798551,454Cite
Inhibition of dental plaque acid production by the salivary lactoperoxidase antimicrobial system.
Tenovuo J, Mansson-Rahemtulla B, Pruitt KM, Arnold R.Infect Immun. 1981 Oct;34(1):208-14. doi: 10.1128/iai.34.1.208-214.1981.PMID: 7298182 Free PMC article.
Supplementation of saliva with an appropriate combination of thiocyanate and hydrogen peroxide resulted in a significant increase in the concentration of OSCN- ions and in more effective inhibition of plaque acid production. …1,455Cite
[Experimental therapy and mechanism of action of nithiocyamine on Schistosoma japonica].
Yu HZ.Yao Xue Xue Bao. 1981 Sep;16(9):641-7.PMID: 7331811 Chinese. No abstract available.1,456Cite
[Tolerance of nitroscanate in dogs].
Bachmann J, Somerville JM.Schweiz Arch Tierheilkd. 1981 Sep;123(9):491-4.PMID: 7302556 German. No abstract available.1,457Cite
Sen HG, Deb BN.Am J Trop Med Hyg. 1981 Sep;30(5):992-8. doi: 10.4269/ajtmh.1981.30.992.PMID: 72830171,458Cite
Miao DL.Zhonghua Nei Ke Za Zhi. 1981 Aug;20(8):475-8.PMID: 7338081 Chinese. No abstract available.1,459Cite
Virion A, Deme D, Pommier J, Nunez J.Eur J Biochem. 1981 Aug;118(2):239-45. doi: 10.1111/j.1432-1033.1981.tb06392.x.PMID: 7285920 Free article. No abstract available.1,460Cite
Krapez JR, Vesey CJ, Adams L, Cole PV.Br J Anaesth. 1981 Aug;53(8):793-804. doi: 10.1093/bja/53.8.793.PMID: 7272142 Free article.
Dogs given thiosulphate 75 mg kg-1 had significantly lower plasma and red cell cyanide concentrations while plasma thiocyanate concentrations were significantly increased in comparison with control. These changes were associated with only minimal disturbance of tissue oxyg …1,461Cite
Schneider YJ, Trouet A.Eur J Biochem. 1981 Aug;118(1):33-8. doi: 10.1111/j.1432-1033.1981.tb05482.x.PMID: 6793366 Free article.
We conclude that important steps (binding to cell surface, delivery to lysosomes, digestion and recycling of plasma membrane) involved in the uptake and the processing of IgG by fibroblasts are inhibited by these two substances. The effects of lysosomotropic agents on the …1,462Cite
Chryssomallis GS, Torgerson PM, Drickamer HG, Weber G.Biochemistry. 1981 Jul 7;20(14):3955-9. doi: 10.1021/bi00517a002.PMID: 67930601,463Cite
Fatal poisoning with methyl isothiocyanate.
Sharma BK, Singh S, Mehta R.Br Med J (Clin Res Ed). 1981 Jul 4;283(6283):18-9. doi: 10.1136/bmj.283.6283.18-a.PMID: 6788245 Free PMC article. No abstract available.1,464Cite
[Amoscanate induced liver injury. I. Clinical observation (author’s transl)].
Miao HZ.Zhonghua Nei Ke Za Zhi. 1981 Jul;20(7):430-2.PMID: 7327065 Chinese. No abstract available.1,465Cite
Antischistosomal effects of cyclosporin A.
Bueding E, Hawkins J, Cha YN.Agents Actions. 1981 Jul;11(4):380-3. doi: 10.1007/BF01982474.PMID: 72824891,466Cite
Russell JT, Holz RW.J Biol Chem. 1981 Jun 25;256(12):5950-3.PMID: 6972377 Free article.
When the medium pH was 7, the pH gradient collapsed in the presence of ammonium sulfate or the combination of nigericin and K+. Measurement of the thiocyanate distribution across the vesicle membrane suggested the existence of an inside negative membrane potential. …1,467Cite
Wang ZH.Zhonghua Nei Ke Za Zhi. 1981 Jun;20(6):355-7.PMID: 7318592 Chinese. No abstract available.1,468Cite
[Analysis of 62 cases of acute schistosomiasis japonica treated with pyquiton or nithiocyamine].
Chen MG, Fu S, Yang JS, Wang MJ, Zhu PJ, Cheng ZG, Wang JP, Tao CG, Liu BL, Shen SB.Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1981 Jun;3 Suppl 1:52-5.PMID: 6459879 Chinese. No abstract available.1,469Cite
Chen MG.Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1981 Jun;3(2):134-5.PMID: 6458409 Chinese. No abstract available.1,470Cite
Wagner G, Briel D.Pharmazie. 1981 Jun;36(6):400-2.PMID: 6169096 German.1,471Cite
Lysis of Streptococcus mutans by hen egg white lysozyme and inorganic sodium salts.
Goodman H, Pollock JJ, Katona LI, Iacono VJ, Cho MI, Thomas E.J Bacteriol. 1981 May;146(2):764-74. doi: 10.1128/jb.146.2.764-774.1981.PMID: 7217017 Free PMC article.1,472Cite
Peptidoglycan loss during hen egg white lysozyme-inorganic salt lysis of Streptococcus mutans.
Goodman H, Pollock JJ, Iacono VJ, Wong W, Shockman GD.J Bacteriol. 1981 May;146(2):755-63. doi: 10.1128/jb.146.2.755-763.1981.PMID: 7217016 Free PMC article.1,473Cite
Lactoperoxidase-catalyzed inactivation of hexokinase.
Adamson M, Pruitt KM.Biochim Biophys Acta. 1981 Apr 14;658(2):238-47. doi: 10.1016/0005-2744(81)90294-1.PMID: 7248302
The enzymatic activity of hexokinase (ATP : D-hexose 6-phosphotransferase, EC 2.7.1.1) decreased rapidly when the enzyme was exposed to the lactoperoxidase antimicrobial system (consisting of lactoperoxidase, H2O2 and SCN-). Inactivation did not begin until the reaction of …1,474Cite
Peroxidase antimicrobial system of human saliva: requirements for accumulation of hypothiocyanite.
Thomas EL, Bates KP, Jefferson MM.J Dent Res. 1981 Apr;60(4):785-96. doi: 10.1177/00220345810600040401.PMID: 6937515
Human saliva was fractionated to determine the components required for production and accumulation of the antimicrobial oxidizing agent, hypothiocyanite ion (OSCN-). The required components were: 1) peroxidase activity and thiocyanate ion (SCN-), 2) the saliva sedim …1,475Cite
Thiocyanate as a cofactor in myeloperoxidase activity against Streptococcus mutans.
Kersten HW, Moorer WR, Wever R.J Dent Res. 1981 Apr;60(4):831-7. doi: 10.1177/00220345810600041201.PMID: 6259229
Inhibition of glycolysis of some oral bacteria was established in vitro by an antibacterial system, consisting of myeloperoxidase, H2O2, and a cofactor. When thiocyanate was used in physiological concentration as a cofactor, the system acted (at low pH) bactericidally on S …1,476Cite
Effect of iodine and thiocyanate on their accumulation in the saliva of sheep.
Bobek S, Hódziec U, Pyska H, Bielański A.Acta Physiol Pol. 1981 Mar-Apr;32(2):213-18.PMID: 7270222 No abstract available.1,477Cite
Sica V, Weisz A, Petrillo A, Armetta I, Puca GA.Biochemistry. 1981 Feb 17;20(4):686-93. doi: 10.1021/bi00507a003.PMID: 72136021,478Cite
Mankodi NA, Vaidya AB, Pillay MG, Nargunde HS, Paul T, Sheth UK, Kaul CL, Nair KG.J Assoc Physicians India. 1981 Feb;29(2):109-13.PMID: 7263597 No abstract available.1,479Cite
Packer JE, Mahood JS, Willson RL, Wolfenden BS.Int J Radiat Biol Relat Stud Phys Chem Med. 1981 Feb;39(2):135-41. doi: 10.1080/09553008114550151.PMID: 6971825
The trichloromethyl peroxy radical Cl3COO reacts with tryptophan, tryptophanyl-tyrosine and with lysozyme to form products whose overall absorption spectrum is different from those observed following the reaction of hydroxyl, bromide, thiocyanate or azide radicals. Two spe …1,480Cite
Bauman JG, Wiegant J, van Duijn P.J Histochem Cytochem. 1981 Feb;29(2):227-37. doi: 10.1177/29.2.6166653.PMID: 61666531,481Cite
Moore AL, Bonner WD Jr.Biochim Biophys Acta. 1981 Jan 14;634(1):117-28. doi: 10.1016/0005-2728(81)90132-8.PMID: 74704951,482Cite
Thilly CH.Bull Mem Acad R Med Belg. 1981;136(7):389-412.PMID: 7326498 French. No abstract available.1,483Cite
Robinson A, Lewert RM.Trans R Soc Trop Med Hyg. 1981;75(3):415-7. doi: 10.1016/0035-9203(81)90108-5.PMID: 73241091,484Cite
Batzinger RP, Bueding E, Popper H.Hepatology. 1981 Jan-Feb;1(1):21-7. doi: 10.1002/hep.1840010104.PMID: 72868881,485Cite
Susceptibility of Legionella pneumophila to three cooling tower microbicides.
Grace RD, Dewar NE, Barnes WG, Hodges GR.Appl Environ Microbiol. 1981 Jan;41(1):233-6. doi: 10.1128/aem.41.1.233-236.1981.PMID: 7224623 Free PMC article.
The objective of this study was to determine the antimicrobial activity of three chemically different, commercially available, cooling tower microbicides against L. pneumophila. Using two in vitro test systems, a combination of N-alkyl dimethyl benzyl ammonium chloride and …1,486Cite
The mechanism of maleic acid nephropathy: investigations using brush border membrane vesicles.
Silverman M.Membr Biochem. 1981;4(1):63-9. doi: 10.3109/09687688109065423.PMID: 72191951,487Cite
Anttonen T, Tenovuo J.Proc Finn Dent Soc. 1981;77(6):318-23.PMID: 7038672 No abstract available.1,488Cite
Study of the efficacy of compound Go.9333 (Ciba-Geigy) in hookworm infestation.
Singh DS, Bala-Subramaniam R, Bhatia VN, Kumar V, Chandrasekar S.Chemotherapy. 1981;27(3):220-3. doi: 10.1159/000237981.PMID: 7014129 Clinical Trial.1,489Cite
Pollock JJ, Katona LI, Goodman H, Cho MI, Iacono VJ.Arch Oral Biol. 1981;26(9):711-6. doi: 10.1016/0003-9969(81)90187-4.PMID: 6950715 No abstract available.1,490Cite
Hemadsorption and fluorescence determinations for assay of virus-yield reduction by interferon.
Hahon N.Methods Enzymol. 1981;78(Pt A):373-81. doi: 10.1016/0076-6879(81)78144-8.PMID: 6173615 No abstract available.1,491Cite
Large-scale production and purification of human lymphoblastoid interferon.
Bodo G.Acta Microbiol Acad Sci Hung. 1981;28(3):263-70.PMID: 6171140 No abstract available.1,492Cite
Soumarmon A, Abastado M, Bonfils S, Lewin MJ.J Biol Chem. 1980 Dec 25;255(24):11682-7.PMID: 7440565 Free article.1,493Cite
The reactivation of human interferons by guanidine thiocyanate.
Jariwalla RJ, Sedmak JJ, Grossberg SE.Experientia. 1980 Dec 15;36(12):1390-1. doi: 10.1007/BF01960115.PMID: 6162669
The addition of 1.5 M guanidine thiocyanate (GuSCN) reactivates inactive human leukocyte interferon. The biological activity of inactivated human fibroblast interferon can be only partially recovered with GuSCN if additional (thermal) energy is supplied….1,494Cite
N-Nitroso compounds from reactions of nitrite with methylamine.
Obiedzinski MW, Wishnok JS, Tannenbaum SR.Food Cosmet Toxicol. 1980 Dec;18(6):585-9. doi: 10.1016/s0015-6264(80)80005-8.PMID: 7053236 No abstract available.1,495Cite
Comparison of praziquantel, amoscanate and hexachloroparaxylol in clonorchiasis sinensis.
Wang QN, Liu JB, Liu YH, Chen RX, Qiu ZD, Qu ZQ.Chin Med J (Engl). 1980 Dec;93(12):849-56.PMID: 6780274 Clinical Trial. No abstract available.1,496Cite
The reconstituted (Na,K)-ATPase is electrogenic.
Dixon JF, Hokin LE.J Biol Chem. 1980 Nov 25;255(22):10681-6.PMID: 6253484 Free article. No abstract available.1,497Cite
Opposite effects of thiocyanate on tyrosine iodination and thyroid hormone synthesis.
Virion A, Deme D, Pommier J, Nunez J.Eur J Biochem. 1980 Nov;112(1):1-7. doi: 10.1111/j.1432-1033.1980.tb04979.x.PMID: 7449758 Free article.1,498Cite
Cyanide, protein and iodine interactions in the performance, metabolism and pathology of pigs.
Tewe OO, Maner JH.Res Vet Sci. 1980 Nov;29(3):271-6.PMID: 7255888
Protein deficiency reduced urinary iodine excretion and the concentrations in serum of protein, protein bound iodine and thiocyanate. It also reduced liver rhodanese activity and caused a decrease in urinary thiocyanate excretion which was not significant. Dietary c …1,499Cite
Role of the proton electrochemical gradient in monoamine transport by bovine chromaffin granules.
Scherman D, Henry JP.Biochim Biophys Acta. 1980 Oct 2;601(3):664-77. doi: 10.1016/0005-2736(80)90567-2.PMID: 74174441,500Cite
Voge M, Bueding E.Exp Parasitol. 1980 Oct;50(2):251-9. doi: 10.1016/0014-4894(80)90026-0.PMID: 7409075 No abstract available.1,501Cite
Distribution and forms of iodine in human oral cavity.
Tenovuo J, Söderling E, Anttonen T.Scand J Dent Res. 1980 Oct;88(5):430-5. doi: 10.1111/j.1600-0722.1980.tb01249.x.PMID: 7008178
A positive correlation between salivary and crevicular excretion of I- from plasma was observed. Thiocyanate ions, which competitively inhibit peroxidase-catalysed oxidation and iodination reactions and which are abundant in human saliva, possibly prevent the coupling of I …1,502Cite
Marshall VM, Reiter B.J Gen Microbiol. 1980 Oct;120(2):513-6. doi: 10.1099/00221287-120-2-513.PMID: 6785388
It has been suggested that the antibacterial activity of the lactoperoxidase/thiocyanate/hydrogen peroxide system is due to the hypothiocyanite anion. Relatively pure solutions of hypothiocyanite can be prepared using an immobilized enzyme. …As similar effects have been …1,503Cite
Anion selectivity of the chloride-transport process in dog tracheal epithelium.
Widdicombe JH, Welsh MJ.Am J Physiol. 1980 Sep;239(3):C112-7. doi: 10.1152/ajpcell.1980.239.3.C112.PMID: 7435549
In addition, we have partly replaced the bathing chloride with bromide, iodide, or thiocyanate and studied the effects of these anions on 36Cl fluxes. Our results show that the affinity sequence for the chloride transport process is I > Br congruent to Cl, that Br is tr …1,504Cite
Carlsson J.Infect Immun. 1980 Sep;29(3):1190-2. doi: 10.1128/iai.29.3.1190-1192.1980.PMID: 7429633 Free PMC article.
Streptococcus sanguis and Peptostreptococcus anaerobius were exposed to various combinations of the components of the lactoperoxidase-thiocyanate-hydrogen peroxide system. The bactericidal effect of hydrogen peroxide was prevented under anaerobic conditions by lactoperoxid …1,505Cite
Hypothiocyanite ion: detection of the antimicrobial agent in human saliva.
Thomas EL, Bates KP, Jefferson MM.J Dent Res. 1980 Sep;59(9):1466-72. doi: 10.1177/00220345800590090201.PMID: 6931123
Also, dietary carbohydrate may inhibit OSCN- accumulation and antimicrobial action in saliva….1,506Cite
The efficacy of amoscanate (C9333-Go/CGP 4540) on filarial infections of Mastomys natalensis.
Sänger I, Lämmler G, Wegerhof PH.Acta Trop. 1980 Sep;37(3):262-5.PMID: 6106365 No abstract available.1,507Cite
Schneider EG, Sacktor B.J Biol Chem. 1980 Aug 25;255(16):7645-9.PMID: 7400138 Free article. No abstract available.1,508Cite
Monovalent cation/proton antiporters in membrane vesicles from Bacillus alcalophilus.
Mandel KG, Guffanti AA, Krulwich TA.J Biol Chem. 1980 Aug 10;255(15):7391-6.PMID: 7391087 Free article. No abstract available.1,509Cite
[Newer antimycotics. VII. N-aryl-dithiocarbamic-esters and carbylaminochlorides (author’s transl)].
Zsolnai T.Zentralbl Bakteriol A. 1980 Aug;247(3):410-7.PMID: 7424251 German.1,510Cite
Wang ZT, Wang DN, Li Q, Ouyang HJ.Yao Xue Xue Bao. 1980 Aug;15(8):463-9.PMID: 7211390 Chinese. No abstract available.1,511Cite
Audiogenic seizures and cochlear damage in rats after perinatal antithyroid treatment.
Van Middlesworth L, Norris CH.Endocrinology. 1980 Jun;106(6):1686-90. doi: 10.1210/endo-106-6-1686.PMID: 61545691,512Cite
Allergic contact dermatitis from methylisothiocyanate in soil disinfectants.
Richter G.Contact Dermatitis. 1980 Apr;6(3):183-6. doi: 10.1111/j.1600-0536.1980.tb05595.x.PMID: 64464341,513Cite
[No authors listed]Zhonghua Nei Ke Za Zhi. 1980 Mar;19(2):132-4.PMID: 7472043 Chinese. No abstract available.1,514Cite
Identification of the major urinary metabolites of acrylonitrile in the rat.
Langvardt PW, Putzig CL, Braun WH, Young JD.J Toxicol Environ Health. 1980 Mar;6(2):273-82. doi: 10.1080/15287398009529851.PMID: 7392095
Two major urinary metabolites were identified as thiocyanate and N-acetyl-S-(2-cyanoethyl)cysteine. A third was tentatively identified as 4-acetyl-3-carboxy-5-cyanotetrahydro-1,4-2H-thiazine. …1,515Cite
Bactericidal activity of eosinophil peroxidase.
Jong EC, Henderson WR, Klebanoff SJ.J Immunol. 1980 Mar;124(3):1378-82.PMID: 6987309
A partially purified preparation of guinea pig eosinophil peroxidase was found to be bactericidal when combined with H2O2 and either iodide, bromide, chloride, or thiocyanate ions. The EPO-H2O2-halide bactericidal system had an acid pH optimum and was inhibited by the prot …1,516Cite
Evidence that iodide transport into human polymorphonuclear leukocytes is not an active process.
Lam DC, Lindsay RH.J Reticuloendothel Soc. 1980 Mar;27(3):281-8.PMID: 6245209 No abstract available.1,517Cite
Determination of the mitochondrial protonmotive force in isolated hepatocytes.
Hoek JB, Nicholls DG, Williamson JR.J Biol Chem. 1980 Feb 25;255(4):1458-64.PMID: 7354039 Free article.
Mitochondrial and plasma membrane potentials of 161 and 32.8 mV (negative inside), respectively, were calculated from the intracellular accumulation of triphenylmethylphosphonium (TPMP+) and thiocyanate in the intact hepatocyte, assuming a two-compartment model. The predom …1,518Cite
Ranganayaki S, Srivastava B, Bahadur K.Zentralbl Bakteriol Naturwiss. 1980;135(3):265-9. doi: 10.1016/s0323-6056(80)80034-6.PMID: 7424225
The photochemically formed microstructures, synthesized in sterilized aqueous mixture containing ammonium thiocyanate and formaldehyde in appropriate mineral environment in the presence of ferric chloride, on exposure to sunlight revealed the presence of phospholipids. …1,519Cite
New findings on acrylonitrile metabolism.
Kopecký J, Zachardová D, Gut I.Czech Med. 1980;3(4):295-301.PMID: 7227125
The mechanism of the metabolic pathway of acrylonitrile to cyanide (and subsequently to thiocyanate which is excreted in the urine) was already previously confirmed by our work in vitro as well as in vivo. …By means of AN labelled with 14C on the nitrile group it was con …1,520Cite
Current results in the clinical therapy of schistosomiasis mansoni.
Katz N.Rev Inst Med Trop Sao Paulo. 1980 Jan-Feb;22(1 Suppl 4):8-17, 123-33.PMID: 7006041 Review. English, Portuguese. No abstract available.1,521Cite
Reiter B, Marshall VM, Philips SM.Res Vet Sci. 1980 Jan;28(1):116-22.PMID: 6990446
The lactoperoxidase was provided by the milk and the thiocyanate either by the milk or by its secretion in the abomasum. The third factor was provided either by a H2O2 generating system (glucose oxidase and glucose) or by H2O2 producing lactobacilli. …1,522Cite
Tenovuo J, Anttonen T.Caries Res. 1980;14(5):269-75. doi: 10.1159/000260464.PMID: 6931636 No abstract available.1,523Cite
Metabolism of several insecticides by glutathion S-transferase.
Fukami J.Pharmacol Ther. 1980;10(3):473-514. doi: 10.1016/0163-7258(80)90028-5.PMID: 6160598 Review. No abstract available.1,524Cite
Edidin M, Wei T, Holmberg S.Ann N Y Acad Sci. 1980;339:1-7. doi: 10.1111/j.1749-6632.1980.tb15963.x.PMID: 6156616 No abstract available.1,525Cite
A technique of silver impregnation for nervous tissues with some thiocyanates.
Ogawa Y.Anat Anz. 1980;147(1):47-50.PMID: 6156609
Taking advantage of some properties of thiocyanates, a technique of silver impregnation for nerve fibres in the human central nervous system is described. The following procedure is suggested: frozen sections 25-35 micrometer thick, 5-10% aqueous solution of ammonium th …1,526Cite
Orlov NIa, Gasparian AG, Fesenko EE.Biofizika. 1980 Jan-Feb;25(1):63-70.PMID: 6154486 Russian.1,527Cite
Mutagenic activation of an antischistosomal drug by enteric Streptococcus sps in vitro and in vivo.
Molineaux CJ, Batzinger RP, Schmidt W, Bueding E.Teratog Carcinog Mutagen. 1980;1(2):129-39. doi: 10.1002/tcm.1770010202.PMID: 6119805
Mutagenicity can be eliminated by coadministration of some antibacterial agents and is not demonstrable in germ-free animals. The present study describes attempts to isolate and identify intestinal microorganisms responsible for the mutagenic activation of amoscanate. Stre …1,528Cite
Ethanol-stimulated acid secretion in the isolated whole stomach of the rat.
Bunce KT, Parsons ME.J Pharm Pharmacol. 1980 Jan;32(1):45-8. doi: 10.1111/j.2042-7158.1980.tb12843.x.PMID: 6102126
The acid response to ethanol was significantly, but not completely inhibited by 10 mM thiocyanate, indicating the existence of an acid component of non-arietal cell origin in the mucosal bathing solution. …1,529Cite
Improved 125I-ligands for gentamicin radioimmunoassay.
Watson RA, Landon J, Edwards CR, Shaw EJ.J Antimicrob Chemother. 1979 Nov;5(6):673-80. doi: 10.1093/jac/5.6.673.PMID: 575361 No abstract available.1,530Cite
Antibacterial action of lactoperoxidase-thiocyanate-hydrogen peroxide on Streptococcus agalactiae.
Mickelson MN.Appl Environ Microbiol. 1979 Nov;38(5):821-6. doi: 10.1128/aem.38.5.821-826.1979.PMID: 396883 Free PMC article.
Antibacterial activity of lactoperoxidase (LP)-thiocyanate (SCN)-hydrogen peroxide (H2O2) on Streptococcus agalactiae requires that the three reactants must be in contact with the cells simultaneously. …1,531Cite
Gemmell MA, Johnstone PD, Oudemans G.Res Vet Sci. 1979 Sep;27(2):255-7.PMID: 5238201,532Cite
Haugwitz RD, Maurer BV, Jacobs GA, Narayanan VL, Cruthers L, Szanto J.J Med Chem. 1979 Sep;22(9):1113-8. doi: 10.1021/jm00195a021.PMID: 4905581,533Cite
Effects of prolonged cyanide and thiocyanate feeding in rats.
Philbrick DJ, Hopkins JB, Hill DC, Alexander JC, Thomson RG.J Toxicol Environ Health. 1979 Jul;5(4):579-92. doi: 10.1080/15287397909529770.PMID: 490674
Male weaning rats were fed a semipurified diet containing 10% casein; this diet restricted in methionine, vitamin B12, and iodine; or the complete and restricted diets supplemented with either 1500 ppm potassium cyanide or 2240 ppm potassium thiocyanate for 11.5 mo. There …1,534Cite
Papas A, Ingalls JR, Campbell LD.J Nutr. 1979 Jul;109(7):1129-39. doi: 10.1093/jn/109.7.1129.PMID: 448457
Similarly the glucosinolate aglucones, isothiocyanates or vinyl oxazolidinethione, were not transferred to milk although small amounts of unsaturated nitrile (1-cyano-2-hydroxy-3-butene) and inorganic thiocyanate were detected in milk. Rats receiving milk from cows fed Tur …1,535Cite
Active transport of calcium in Neurospora plasma membrane vesicles.
Stroobant P, Scarborough GA.Proc Natl Acad Sci U S A. 1979 Jul;76(7):3102-6. doi: 10.1073/pnas.76.7.3102.PMID: 40223 Free PMC article.1,536Cite
Lactoperoxidase binding to streptococci.
Pruitt KM, Adamson M, Arnold R.Infect Immun. 1979 Jul;25(1):304-9. doi: 10.1128/iai.25.1.304-309.1979.PMID: 39032 Free PMC article.
We describe here the effects of cell-bound lactoperoxidase on acid production by suspensions of Streptococcus mutans (NCTC 10449) in the presence of hydrogen peroxide and thiocyanate. Saline suspensions of log-phase bacteria were treated with 0.1 mg of lactoperoxidase per …1,537Cite
4-nitro-4′ isothiocyane-diphenylamine–a new anthelmintic in hookworm infestation.
Gupta PS, Gambhir DS, Oswal S, Kumar N.J Trop Med Hyg. 1979 Jun;82(6):117-9.PMID: 501765 Clinical Trial. No abstract available.1,538Cite
Anti-nutrient factors affecting mineral utilization.
Davies NT.Proc Nutr Soc. 1979 May 1;38(1):121-8. doi: 10.1079/pns19790016.PMID: 88737 Review. No abstract available.1,539Cite
Ferguson SJ, Jones OT, Kell DB, Sorgato MC.Biochem J. 1979 Apr 15;180(1):75-85. doi: 10.1042/bj1800075.PMID: 226068 Free PMC article.1,540Cite
Transport of local anaesthetics across chromatophore membranes.
Packham NK, Jackson JB.Biochim Biophys Acta. 1979 Apr 11;546(1):142-56. doi: 10.1016/0005-2728(79)90176-2.PMID: 312654
In the presence of membrane potential-collapsing agents, such as valinomycin/K+ or thiocyanate ions, local anaesthetics decelerate the decay of the cresol red change but have no effect on the carotenoid shift decay. …Ca2+ interferes with the mechanism of local ana …1,541Cite
The electrogenic nature of ADP/ATP transport in inside-out submitochondrial particles.
Villiers C, Michejda JW, Block M, Lauquin GJ, Vignais PV.Biochim Biophys Acta. 1979 Apr 11;546(1):157-70. doi: 10.1016/0005-2728(79)90177-4.PMID: 36139 No abstract available.1,542Cite
Godfrey C.Vet Rec. 1979 Apr 7;104(14):328. doi: 10.1136/vr.104.14.328.PMID: 552700 No abstract available.1,543Cite
Terada H, Kubota S.FEBS Lett. 1979 Apr 1;100(1):37-40. doi: 10.1016/0014-5793(79)81126-6.PMID: 437106 Free article. No abstract available.1,544Cite
Anthelmintic activity of Sch 20350 in dogs.
Loebenberg D, Nafissi-V MM, Antonacci B, Waitz JA.J Parasitol. 1979 Apr;65(2):233.PMID: 286783 No abstract available.1,545Cite
Evidence against a MgATP-dependent proton pump in rat-liver lysosomes.
Hollemans M, Reijngoud DJ, Tager JM.Biochim Biophys Acta. 1979 Feb 20;551(1):55-66. doi: 10.1016/0005-2736(79)90352-3.PMID: 34437
The effect of MgATP has been studied on the accumulation of the lipid-soluble anion thiocyanate, the accumulation of the lipid-soluble base methylamine, and the fluorescence of bound anilinonaphthalene sulphonate in rat-liver lysosomes. The lysosomes used were isolated fro …1,546Cite
Middleton KR, Schaefer FW 3rd, Saz HJ.Experientia. 1979 Feb 15;35(2):243-4. doi: 10.1007/BF01920641.PMID: 4218461,547Cite
Nitroscanate A new broad spectrum anthelmintic against nematodes and cestodes of dogs and cats.
Boray JC, Strong MB, Allison JR, von Orelli M, Sarasin G, Gfeller W.Aust Vet J. 1979 Feb;55(2):45-53. doi: 10.1111/j.1751-0813.1979.tb15157.x.PMID: 444159 No abstract available.1,548Cite
Batzinger RP, Bueding E, Crawford K, Bruce J.Environ Mutagen. 1979;1(4):353-60. doi: 10.1002/em.2860010407.PMID: 5538071,549Cite
[Pharmacokinetic and microbiological studies of Pharmachem erythromycin asparate].
Doneva M, Bineva I.Vet Med Nauki. 1979;16(9):58-64.PMID: 120997 Bulgarian.1,550Cite
Elution of chicken Ig from fixed target cells.
Nicolaisen EM, Simonsen M.J Immunol Methods. 1979;29(2):139-44. doi: 10.1016/0022-1759(79)90063-2.PMID: 1134661,551Cite
Cha YN, Bueding E.Am J Trop Med Hyg. 1978 Nov;27(6):1188-91. doi: 10.4269/ajtmh.1978.27.1188.PMID: 7273231,552Cite
Active transport of L-glutamate by membrane vesicles isolated from rat brain.
Kanner BI, Sharon I.Biochemistry. 1978 Sep 19;17(19):3949-53. doi: 10.1021/bi00612a011.PMID: 708689
Transport is enhanced by valinomycin or by external thiocyanate ions and is about 50% inhibited by the proton ionophore carbonyl cyanide m-chlorophenylhydrazone. …1,553Cite
Davidson B, Soodak M, Neary JT, Strout HV, Kieffer JD, Mover H, Maloof F.Endocrinology. 1978 Sep;103(3):871-82. doi: 10.1210/endo-103-3-871.PMID: 744122
Preincubation, as above, in the presence of iodide or thiocyanate prevented the irreversible inactivation of TPO. Rats receiving doses of these drugs which completely inhibited protein-bound iodine formation showed normal levels of TPO in their thyroid glands 30 min after …1,554Cite
Effect of linamarin on thiocyanate production and thyroid activity in rats.
Barret MD, Alexander JC, Hill DC.J Toxicol Environ Health. 1978 Sep-Nov;4(5-6):735-40. doi: 10.1080/15287397809529695.PMID: 731726
The plasma thiocyanate concentration was also higher for linamarin-fed animals than for animals that did not receive linamarin. Higher plasma thiocyanate levels were associated with a lower percentage uptake of radioiodine by the thyroid….1,555Cite
The lactoperoxidase-thiocyanate-hydrogen peroxide antibacterium system.
Reiter B.Ciba Found Symp. 1978 Jun 6-8;(65):285-94. doi: 10.1002/9780470715413.ch16.PMID: 225143
Lactoperoxidase present in various secretions oxidizes thiocyanate (SCN-) in the presence of H2O2 to an unstable oxidation product–hypothiocyanite (OSCN-), which is bactericidal for enteric pathogens including multiple antibiotic resistant strains of E. coli. …1,556Cite
Large-scale production of human leukocyte interferon containing 10(8) units per ml.
Cantell K, Hirvonen S.J Gen Virol. 1978 Jun;39(3):541-3. doi: 10.1099/0022-1317-39-3-541.PMID: 26729 No abstract available.1,557Cite
Thomas EL, Aune TM.Infect Immun. 1978 May;20(2):456-63. doi: 10.1128/iai.20.2.456-463.1978.PMID: 352945 Free PMC article.
The antimicrobial activity of the lactoperoxidase, peroxide, thiocyanate system against Escherichia coli was directly related to the oxidation of bacterial sulfhydryls. Lactoperoxidase catalyzed the oxidation of thiocyanate, which resulted in the accumulation …1,558Cite
Nishino H, Schiller RM, Parnes JR, Isselbacher KJ.Proc Natl Acad Sci U S A. 1978 May;75(5):2329-32. doi: 10.1073/pnas.75.5.2329.PMID: 79182 Free PMC article.1,559Cite
Etiological factors of endemic goiter in north-eastern Sicily.
Delange F, Vigneri R, Trimarchi F, Filetti S, Pezzino V, Squatrito S, Bourdoux P, Ermans AM.J Endocrinol Invest. 1978 Apr;1(2):137-42. doi: 10.1007/BF03350361.PMID: 755849 No abstract available.1,560Cite
[An anti-bacterial system in the saliva].
Rotgans J.Dtsch Zahnarztl Z. 1978 Apr;33(4):280-4.PMID: 25761 Review. German. No abstract available.1,561Cite
Formation of a mutagenic drug metabolite by intestinal microorganisms.
Batzinger RP, Bueding E, Reddy BS, Weisburger JH.Cancer Res. 1978 Mar;38(3):608-12.PMID: 414832
This suggests a new approach for increasing the safety of pharmacological agents….1,562Cite
van Amelsvoort JM, van Hoof PM, de Pont JJ, Bonting SL.Biochim Biophys Acta. 1978 Feb 2;507(1):83-93. doi: 10.1016/0005-2736(78)90376-0.PMID: 1465181,563Cite
Thomas EL, Aune TM.Antimicrob Agents Chemother. 1978 Feb;13(2):261-5. doi: 10.1128/AAC.13.2.261.PMID: 348097 Free PMC article.
The bactericidal action that results from lactoperoxidase-catalyzed oxidation of iodide or thiocyanate was studied, using Escherichia coli as the test organism. The susceptibility of intact cells to bactericidal action was compared with that of cells with altered cell enve …1,564Cite
Kreutler PA, Varbanov V, Goodman W, Olaya G, Stanbury JB.Am J Clin Nutr. 1978 Feb;31(2):282-9. doi: 10.1093/ajcn/31.2.282.PMID: 74949 No abstract available.1,565Cite
Lathia D, Brendebach M.Clin Chim Acta. 1978 Jan 16;82(3):209-14. doi: 10.1016/0009-8981(78)90001-3.PMID: 23226
A strong simulating effect of thiocyanate ions during the estimation of alpha-amylase by the amyloclastic method is shown. …The rate of thiocyanate-iodine reaction depends upon the hydrogen ion concentration of the iodine reagent….1,566Cite
Sawlewicz J, Wisterowicz K, Janowiec M.Acta Pol Pharm. 1978;35(4):413-6.PMID: 707151 Polish. No abstract available.1,567Cite
Sawlewicz J, Wisterowicz K, Janowiec M.Acta Pol Pharm. 1978;35(4):403-11.PMID: 707150 Polish. No abstract available.1,568Cite
Liberation of cyanide from succinonitrile. 2. The effect of ethanol.
Contessa AR, Floreani M, Bonetti AC, Santi R.Biochem Pharmacol. 1978;27(8):1135-8. doi: 10.1016/0006-2952(78)90441-0.PMID: 697915 No abstract available.1,569Cite
Bourdoux P, Delange F, Vanderlinden L, Ermans AM.Ann Endocrinol (Paris). 1978;39(2):153-4.PMID: 686655 French.
Dietary intake of cassava induces an increase of plasma thiocyanate concentration and an increase of urinary excretion of stable iodine. Generalized iodine deficiency induces very high thyroid uptakes; the other parameters of thyroid function are more or less affected acco …1,570Cite
Cavadore JC.Biochimie. 1978;60(2):203-7. doi: 10.1016/s0300-9084(78)80756-1.PMID: 667174 French.1,571Cite
[Reactions of 1,2,4-triazolothione-3 and various derivatives with isocyanates and isothiocyanates].
Rudnicka W, Sawlewicz J.Acta Pol Pharm. 1978;35(2):135-42.PMID: 665266 Polish. No abstract available.1,572Cite
Review of nonspecific antimicrobial factors in colostrum.
Reiter B.Ann Rech Vet. 1978;9(2):205-24.PMID: 371504 Review. No abstract available.1,573Cite
Chemotherapy of human intestinal parasitic diseases.
Botero D.Annu Rev Pharmacol Toxicol. 1978;18:1-15. doi: 10.1146/annurev.pa.18.040178.000245.PMID: 348055 Review. No abstract available.1,574Cite
Gemmell MA.Bull World Health Organ. 1978;56(3):433-43.PMID: 308408 Free PMC article.1,575Cite
Inhibitors of chemical carcinogenesis.
Wattenberg LW.Adv Cancer Res. 1978;26:197-226. doi: 10.1016/s0065-230x(08)60088-3.PMID: 204165 Review. No abstract available.1,576Cite
Lactoperoxidase-catalysed iodine metabolism in human saliva.
Tenovuo J.Arch Oral Biol. 1978;23(4):253-8. doi: 10.1016/0003-9969(78)90014-6.PMID: 28718 No abstract available.1,577Cite
Tenovuo J, Knuuttila ML.J Dent Res. 1977 Dec;56(12):1603-7. doi: 10.1177/00220345770560123201.PMID: 277482
Physiological activity of lactoperoxidase and in vivo concentration of thiocyanate ions were shown to be inhibitory against a cariogenic strain of Streptococcus mutans. …1,578Cite
Procházka Z, Thoa HK, Stránský K, Leifertová I, Musilek A, Scholz G.Cesk Farm. 1977 Nov;26(9):395-9.PMID: 608202 Czech. No abstract available.1,579Cite
Mickelson MN.J Bacteriol. 1977 Nov;132(2):541-8. doi: 10.1128/jb.132.2.541-548.1977.PMID: 334746 Free PMC article.
Transport of 2-deoxyglucose or glucose in Streptococcus agalactiae was strongly inhibited if the cells were first exposed to a combination of lactoperoxidase-thiocyanate-hydrogen peroxide (LP-complex). The inhibition was completely reversible with dithiothreitol. …1,580Cite
Lactoperoxidase-catalyzed incorporation of thiocyanate ion into a protein substrate.
Aune TM, Thomas EL, Morrison M.Biochemistry. 1977 Oct 18;16(21):4611-5. doi: 10.1021/bi00640a013.PMID: 911776 No abstract available.1,581Cite
Accumulation of hypothiocyanite ion during peroxidase-catalyzed oxidation of thiocyanate ion.
Aune TM, Thomas EL.Eur J Biochem. 1977 Oct 17;80(1):209-14. doi: 10.1111/j.1432-1033.1977.tb11873.x.PMID: 562752 Free article. No abstract available.1,582Cite
Effect of thiocyanate on mammary gland growth in rats.
Pyska H.J Dairy Res. 1977 Oct;44(3):427-31. doi: 10.1017/s0022029900020380.PMID: 591663
In growing rats from 3 weeks to 3 months old, 0.1% potassium thiocyanate (KSCN) decreased the plasma protein-bound iodine level by 47% and the total DNA in the mammary gland by 11%, but had no effect on the total RNA. …The 14-d-old litters of rats receiving thiocyanat …1,583Cite
Some antagonists of dantrolene sodium on the isolated diaphragm muscle of the rat.
Bowman WC, Khan HH, Savage AO.J Pharm Pharmacol. 1977 Oct;29(10):616-25. doi: 10.1111/j.2042-7158.1977.tb11417.x.PMID: 21242
The substances selected as possible dantrolene antagonists were uranyl ions, thiocyanate ions, adrenaline, caffeine, quazodine, quinine, 4-aminopyridine and the calcium ionophore a23187, all of which facilitate excitation-contraction coupling in one way or another. …1,584Cite
Vaidya AB, Sen HG, Mankodi NA, Paul T, Sheth UK.Br J Clin Pharmacol. 1977 Aug;4(4):463-7. doi: 10.1111/j.1365-2125.1977.tb00763.x.PMID: 901739 Free PMC article.1,585Cite
Permeability of the cell envelope and osmotic behavior in Saccharomyces cerevisiae.
Arnold WN, Lacy JS.J Bacteriol. 1977 Aug;131(2):564-71. doi: 10.1128/jb.131.2.564-571.1977.PMID: 407215 Free PMC article.
Plots of S value versus osmolality were linear for uncharged probes and curvilinear for all salts. When Ficoll and potassium thiocyanate were presented to the yeast in admixture, the S values for the salt increased continuously over the range of osmolality studied. …1,586Cite
Doshi JC, Vaidya AB, Sen HG, Mankodi NA, Nair CN, Grewal RS.Am J Trop Med Hyg. 1977 Jul;26(4):636-9. doi: 10.4269/ajtmh.1977.26.636.PMID: 8890041,587Cite
Henderson GB, Zevely EM, Huennekens FM.J Biol Chem. 1977 Jun 10;252(11):3760-5.PMID: 16917 Free article.
Folate could be released by treatment of the micelle with ethanol or with chaotropic agents such as guanidinium chloride, perchlorate, or thiocyanate….1,588Cite
Endemic goitre in Alto Adige (Italy).
Platzer S, Fill H, Riccabona G, Glatzl J, Seidl J, Cenderelli G, Migliardi M, Varetto H, Costa A.Acta Endocrinol (Copenh). 1977 Jun;85(2):325-34. doi: 10.1530/acta.0.0850325.PMID: 68653 No abstract available.1,589Cite
Saz HJ, Dunbar GA, Bueding E.Am J Trop Med Hyg. 1977 May;26(3):574-5. doi: 10.4269/ajtmh.1977.26.574.PMID: 869112 No abstract available.1,590Cite
Use of 1-anilino-8-naphthalene-sulfonate as a probe of gastric vesicle transport.
Lewin M, Saccomani G, Schackmann R, Sachs G.J Membr Biol. 1977 Apr 22;32(3-4):301-18. doi: 10.1007/BF01905224.PMID: 170061,591Cite
Singh R, Raizada RB, Singh TP.Gen Comp Endocrinol. 1977 Apr;31(4):451-6. doi: 10.1016/0016-6480(77)90034-x.PMID: 195863 No abstract available.1,592Cite
Cholesterol Stimulation of Penetration of Unilamellar Liposomes by Hydrophobic Compounds.
LaBelle EF, Racker E.J Membr Biol. 1977 Mar 8;31(3):301-15. doi: 10.1007/BF01869410.PMID: 3217871,593Cite
Flagg JL, Wilson TH.J Membr Biol. 1977 Mar 8;31(3):233-55. doi: 10.1007/BF01869407.PMID: 15125
The membrane potential (inside negative) was established by the outward diffusion of potassium (in the presence of valinomycin) or by the inward diffusion of the permeant thiocyanate ion. The magnitude of the electrochemical potential difference for protons agreed well wit …1,594Cite
Membrane potential of mitochondrial measured with microelectrodes.
Maloff BL, Scordilis SP, Tedeschi H.Science. 1977 Mar 4;195(4281):898-900. doi: 10.1126/science.841317.PMID: 8413171,595Cite
[Effectiveness of jonite and ambilgar in experimental alveococcosis of albino mice].
Cherniaeva AI, Krotov AI.Med Parazitol (Mosk). 1977 Mar-Apr;46(2):224-5.PMID: 927351 Russian. No abstract available.1,596Cite
The metabolism of benzyl isothiocyanate and its cysteine conjugate.
Brüsewitz G, Cameron BD, Chasseaud LF, Görler K, Hawkins DR, Koch H, Mennicke WH.Biochem J. 1977 Jan 15;162(1):99-107. doi: 10.1042/bj1620099.PMID: 15557 Free PMC article.1,597Cite
Transport of cyclitols by a proton symport in Klebsiella aerogenes.
Reber G, Mermod M, Deshusses J.Eur J Biochem. 1977 Jan 3;72(1):93-9. doi: 10.1111/j.1432-1033.1977.tb11228.x.PMID: 12979 Free article.1,598Cite
Zervos C, Adams E.Int J Pept Protein Res. 1977;10(1):1-8. doi: 10.1111/j.1399-3011.1977.tb02770.x.PMID: 8812891,599Cite
Clinical evaluation of a new anthelmintic – C. 9333 Go./CGP 4540 in human hookworm infection.
Vakil BJ, Dalal NJ, Shah PN.Trans R Soc Trop Med Hyg. 1977;71(3):247-50. doi: 10.1016/0035-9203(77)90017-7.PMID: 329490 Clinical Trial.1,600Cite
A new approach for the solid phase sequence determination of proteins.
Chang JY, Creaser EH, Hughes GJ.FEBS Lett. 1977;78(1):147-50. doi: 10.1016/0014-5793(77)80293-7.PMID: 326576 Free article. No abstract available.
Cannon B, Romert L, Sundin U, Barnard T.Comp Biochem Physiol B. 1977;56(1):87-99. doi: 10.1016/0305-0491(77)90227-9.PMID: 318610 Review. No abstract available.1,602Cite
Hoogendoorn H, Piessens JP, Scholtes W, Stoddard LA.Caries Res. 1977;11(2):77-84. doi: 10.1159/000260252.PMID: 265188 No abstract available.1,603Cite
Preparation of human leukocyte interferon for clinical use.
Cantell K, Hirvonen S.Tex Rep Biol Med. 1977;35:138-44.PMID: 29356 No abstract available.1,604Cite
A nonelectrogenic H+ pump in plasma membranes of hog stomach.
Sachs G, Chang HH, Rabon E, Schackman R, Lewin M, Saccomani G.J Biol Chem. 1976 Dec 10;251(23):7690-8.PMID: 12175 Free article.1,605Cite
Hlavatý P, Matoska J, Augustín J, Drobnica L.Mykosen. 1976 Dec;19(12):447-50.PMID: 1004526 German. No abstract available.1,606Cite
Ort DR, Dilley RA.Biochim Biophys Acta. 1976 Oct 13;449(1):95-107. doi: 10.1016/0005-2728(76)90010-4.PMID: 61766
Potassium ions in the presence of valinomycin increase the delay to a maximum of about 50 ms whereas thiocyanate ions increase the delay to a maximum of about 25 ms. The effects of K+ with valinomycin and the effect of SCN- are not additive. …1,607Cite
[Use of Edman’s method for splitting actinoidin peptides and aglycone].
Berdnikova TF, Iurina MS, Lomakina NN.Antibiotiki. 1976 Oct;21(10):924-7.PMID: 999243 Russian.1,608Cite
Björck L.Biotechnol Bioeng. 1976 Oct;18(10):1463-72. doi: 10.1002/bit.260181013.PMID: 989468
Lactoperoxidase catalyzes the oxidation of thiocyanate by hydrogen peroxide and an intermediary product is formed with antibacterial properties. …1,609Cite
Kojima M, Kado M.J Pharm Sci. 1976 Oct;65(10):1551-3. doi: 10.1002/jps.2600651039.PMID: 978421
Fifteen reaction products of isothiocyanates with cysteine, seven reaction products of isothiocyanates with 2,3-dimercapto-1-propanol, and four reaction products of isothiocyanates with sulfanilamide were synthesized. Their antimicrobial activity against pathogenic plant m …1,610Cite
[Vulvitis due to ancylostoma duodenale (author’s transl)].
Hofmann D, Scholz H.Med Klin. 1976 Oct 1;71(40):1688-9.PMID: 967093 German.1,611Cite
Changes in energy metabolism due to anthelmintics in Fasciola hepatica maintained in vitro.
Cornish RA, Bryant C.Int J Parasitol. 1976 Oct;6(5):393-8. doi: 10.1016/0020-7519(76)90024-2.PMID: 965144 No abstract available.1,612Cite
Toxic optic neuropathy and its experimental production.
Brontë-Stewart J, Pettigrew AR, Foulds WS.Trans Ophthalmol Soc U K (1962). 1976 Sep;96(3):355-8.PMID: 1071911 No abstract available.1,613Cite
Broorsma DM, Steefkerk JG, Kors N.J Histochem Cytochem. 1976 Sep;24(9):1017-25. doi: 10.1177/24.9.184204.PMID: 1842041,614Cite
Mickelson MN.Appl Environ Microbiol. 1976 Aug;32(2):238-44. doi: 10.1128/aem.32.2.238-244.1976.PMID: 970943 Free PMC article.
If the concentration of L-cystine was no greater than 4 to 5 mug/ml, complete growth inhibition could be obtained by the addition of lactoperoxidase, thiocyanate, and H2O2. The growth inhibition, however, was nullified by additions of L-cystine 10-fold or more in excess of …1,615Cite
Studies on sequencing of peptides from the carboxyl terminus by using the thiocyanate method.
Rangarajan M, Darbre A.Biochem J. 1976 Aug 1;157(2):307-16. doi: 10.1042/bj1570307.PMID: 962869 Free PMC article.
We report on our experience in applying the thiocyanate method developed by Stark (1968) (Biochemistry 7, 1796-1807) to the sequencing of short peptides from the carboxyl end in free solution. …1,616Cite
Concentration of thiocyanate and ionizable iodine in saliva of smokers and nonsmokers.
Tenovuo J, Mäkinen KK.J Dent Res. 1976 Jul-Aug;55(4):661-3. doi: 10.1177/00220345760550042001.PMID: 1064612
The concentration of thiocyanate and ionizable iodine was determined with saliva samples from two test groups, smokers (N = 27) and nonsmokers (N = 92). …The concentrations of the ions studied were dependent on each other-the less iodine, the more thiocyanate in t …1,617Cite
Vannini GL, Dall’olio G, Giori P.Mycopathologia. 1976 Jun 4;58(1):39-47. doi: 10.1007/BF00493592.PMID: 7786231,618Cite
Bueding E, Batzinger R, Petterson G.Experientia. 1976 May 15;32(5):604-6. doi: 10.1007/BF01990188.PMID: 12783091,619Cite
Efficacy of divided doses of GS-23654 against immature Echinococcus granulosus infections in dogs.
Schantz PM, Prezioso U, Marchevsky N.Am J Vet Res. 1976 May;37(5):621-2.PMID: 12753511,620Cite
Mg2+ and the permeability of heart mitochondria to monovalent cations.
Wehrle JP, Jurkowitz M, Scott KM, Brierley GP.Arch Biochem Biophys. 1976 May;174(1):313-23. doi: 10.1016/0003-9861(76)90350-7.PMID: 7203 No abstract available.1,621Cite
Striebel HP.Experientia. 1976 Apr 15;32(4):457-8. doi: 10.1007/BF01920794.PMID: 8179281,622Cite
Wikström MK, Saari HT.Mol Cell Biochem. 1976 Mar 26;11(1):17-33. doi: 10.1007/BF01792831.PMID: 5667 Review.1,623Cite
The crystal structure of the NH4NCS complex of nonactin.
Neupert-Laves K, Dobler M.Helv Chim Acta. 1976 Mar 10;59(2):614-23. doi: 10.1002/hlca.19760590225.PMID: 946427 No abstract available.1,624Cite
Reiter B, Marshall VM, BjörckL, Rosén CG.Infect Immun. 1976 Mar;13(3):800-7. doi: 10.1128/iai.13.3.800-807.1976.PMID: 5374 Free PMC article.
Two strains of Escherichia coli and one strain each of Salmonella typhimurium and Pseudomonas aeruginosa were killed by the bactericidal activity of the lactoperoxidase-thiocyanate-hydrogen peroxide system in milk and in a synthetic medium. H2O2 was supplied exogenously by …1,625Cite
Calcium transport driven by a proton gradient and inverted membrane vesicles of Escherichia coli.
Tsuchiya T, Rosen BP.J Biol Chem. 1976 Feb 25;251(4):962-7.PMID: 2608 Free article.1,626Cite
Transport of p-aminohippuric acid by plasma membrane vesicles isolated from rat kidney cortex.
Berner W, Kinne R.Pflugers Arch. 1976 Feb 24;361(3):269-77. doi: 10.1007/BF00587292.PMID: 943770
Replacement of a sodium chloride gradient by a sodium thiocyanate gradient reduces the uptake probably by reducing the inside positive membrane potential. …1,627Cite
Mechanism of active shrinkage in mitochondria. II. Coupling between strong electrolyte fluxes.
Azzone GF, Massair S, Pozzan T.Biochim Biophys Acta. 1976 Jan 15;423(1):27-41. doi: 10.1016/0005-2728(76)90098-0.PMID: 23141,628Cite
Jaroszewicz L, Rzeczycki W.Endocrinol Exp. 1976;10(4):243-51.PMID: 1087224
Thiosemicarbazide, thiourea, methylthiouracyl, sulphathiazole, thiocyanate and azides were found to have an inhibiting effect on iodide oxidation. Methimazole inhibits both the oxidation of iodide and incorporation of 131I into protein. …1,629Cite
Sequence determination of proteins with 2-p-isothiocyanophenyl-3-phenylindenone.
Ivanov CP, Mancheva IN.C R Acad Bulg Sci. 1976;29(10):1483-6.PMID: 1017362 No abstract available.1,630Cite
Lipophilicity of isothiocyanates as a criterion of their antimicrobial spectrum.
Drobnica L, Augustin J, Nemec P.Experientia Suppl. 1976;23:65-77. doi: 10.1007/978-3-0348-5795-6_10.PMID: 954948 No abstract available.1,631Cite
Mäkinen KK, Tenovuo J, Scheinin A.Acta Odontol Scand. 1976;34(6):353-69. doi: 10.3109/00016357609004647.PMID: 797223
There were no significant differences between the sugar groups in the concentration of thiocyanate ions (mean 92 mg/l) and ionized iodine (mean 1.6 mug/l), but the concentration of ionized fluorine in saliva was lower in the xylitol group (0.128 mg/l) than in the other gro …1,632Cite
The evolutionary significance of phase-separated microsystems.
Fox SW.Orig Life. 1976 Jan;7(1):49-68. doi: 10.1007/BF01218513.PMID: 787866 Review.1,633Cite
Peroxidase-catalyzed halogenation.
Morrison M, Schonbaum GR.Annu Rev Biochem. 1976;45:861-88. doi: 10.1146/annurev.bi.45.070176.004241.PMID: 786162 Review.
All of the above enzymes except horseradish will oxidize the pseudo halide thiocyanate. The origins of this differentiation remain to be defined, but they presumably reflect significant variation in oxidation potential of different peroxidase-peroxide derivatives, rather t …1,634Cite
[Group-allergic reaction spectrum and sensitization potency of benzylisothiocyanate].
Richter G, Heidelbach U, Heidenbluth I, Kadner H.Berufsdermatosen. 1976;24(6):147-51.PMID: 138417 German.
Neither 4,4-diphenylmethandiisocyanate and isophorondiisocyanate (substances used in polyurethane production) nor the closely related methylisothiocyanate (decomposition product of some potato-selecting agents) produced any groupallergic cross reactions in the above-mentio …1,635Cite
[Permeability of yeast mitochondrial internal membrane: structure-activity relationship].
Chateaubodeau GA, Guérin M, Guérin B.Biochimie. 1976;58(5):601-10. doi: 10.1016/s0300-9084(76)80230-1.PMID: 133731 French.
Phosphate transport seems to be exclusively electrogenic and mersalyl sensitive, but swelling inhibition by that thiol reagent is restored by Mg2+. b) Non respiring mitochondria are impermeable to Cl-, but ATP addition restores the permeability. Thiocyanate permeates as th …1,636Cite
[Determination of blood protein-bound iodine by the nitrite-rhodanide method].
Eremin IuN, Khaĭkis AA, Trubitsyn AA.Lab Delo. 1976;(10):595-7.PMID: 63587 Russian. No abstract available.1,637Cite
Sen HG.Acta Trop. 1976;33(1):101-2.PMID: 13629 No abstract available.1,638Cite
Sugar and amino acid transport in animal cells.
Hopfer U.Horiz Biochem Biophys. 1976;2:106-33.PMID: 6372 Review.1,639Cite
[Extended cutaneous necroses after self-medication of abrasion wounds with Pectocor-ointment].
Sawatzki T, Werner G.Z Arztl Fortbild (Jena). 1975 Dec 1;69(23):1219-21.PMID: 1229161 German. No abstract available.1,640Cite
Kuwano M, Matsui K, Nakashima T, Endo H, Komiyama S.Gan. 1975 Dec;66(6):655-61.PMID: 12257181,641Cite
[Committee on anthelmintics. Residual group].
[No authors listed]Tijdschr Diergeneeskd. 1975 Nov 1;100(21):1156-9.PMID: 1198575 Dutch.1,642Cite
Iodine absorption, excretion, recycling, and tissue distribution in the dairy cow.
Miller JK, Swanson EW, Spalding GE.J Dairy Sci. 1975 Oct;58(10):1578-93. doi: 10.3168/jds.S0022-0302(75)84753-9.PMID: 1184809 Free article.1,643Cite
Skelton FS, Witschi H, Plaa GL.Exp Mol Pathol. 1975 Oct;23(2):171-80. doi: 10.1016/0014-4800(75)90015-5.PMID: 1183536 No abstract available.1,644Cite
Deficient cytochrome b5 reductase activity in nontoxic goiter with iodide organification defect.
Kusakabe T.Metabolism. 1975 Oct;24(10):1103-13. doi: 10.1016/0026-0495(75)90147-x.PMID: 1165726
The thyroid 131I uptake at 3 and 24 hr were, respectively, 77.1% and 81.4% dose. Thiocyanate discharged 65.5% of the accumulated 131I in 30 min. In vitro organification of iodine in the thyroid homogenate from the patient was impaired and it was restored to normal by the a …1,645Cite
Ventriculojugular shunt nephritis with Corynebacterium bovis. Successful therapy with antibiotics.
Bolton WK, Sande MA, Normansell DE, Sturgill BC, Westervelt FB Jr.Am J Med. 1975 Sep;59(3):417-23. doi: 10.1016/0002-9343(75)90401-5.PMID: 1163549
Indirect fluorescein staining of the biopsy specimen with the rabbit antiserum demonstrated 1+ granular glomerular basement membrane deposits. Potassium thiocyanate microelution of sections prior to examination markedly diminished staining with antihuman antiserum, but did …1,646Cite
Zsolnai T.Arzneimittelforschung. 1975 Sep;25(9):1336-9.PMID: 1242655 German.1,647Cite
The effect of nitroscanate on Echinococcus granulosus and Taenia hydatigena infections in dogs.
Gemmell MA, Oudemans G.Res Vet Sci. 1975 Sep;19(2):217-9.PMID: 11726241,648Cite
Effects of iodine level on performance and thyroid traits of growing pigs.
Cromwell GL, Sihombing DT, Hays VW.J Anim Sci. 1975 Sep;41(3):813-8. doi: 10.2527/jas1975.413813x.PMID: 1158812 No abstract available.1,649Cite
Sommer G, Parker D, Turk JL.Immunology. 1975 Sep;29(3):517-25.PMID: 1080744 Free PMC article.1,650Cite
Isothiocyanates. A new class of uncouplers.
Miko M, Chance B.Biochim Biophys Acta. 1975 Aug 11;396(2):165-74. doi: 10.1016/0005-2728(75)90031-6.PMID: 1256071,651Cite
Fluorescein conjugates of cytochrome c as internal pH probes in submitochondrial particles.
Thomas JA, Johnson DL.Biochem Biophys Res Commun. 1975 Aug 4;65(3):931-9. doi: 10.1016/s0006-291x(75)80475-x.PMID: 239716 No abstract available.1,652Cite
Automated microsequence analysis by use of radioactive phenylisothiocyanate.
Silver J, Hood L.Anal Biochem. 1975 Aug;67(2):392-6. doi: 10.1016/0003-2697(75)90310-3.PMID: 1163764 No abstract available.1,653Cite
Chronic cyanide exposure: a clinical, radioisotope, and laboratory study.
El Ghawabi SH, Gaafar MA, El-Saharti AA, Ahmed SH, Malash KK, Fares R.Br J Ind Med. 1975 Aug;32(3):215-9. doi: 10.1136/oem.32.3.215.PMID: 1156569 Free PMC article.
The regression line showing the relationship between thiocyanates in urine and the concentration of cyanides in the air was plotted. Increased percentages of haemoglobin and lymphocyte count were present in all exposed workers, in addition to punctate basophilia in 28 work …1,654Cite
Björck L, Rosén C, Marshall V, Reiter B.Appl Microbiol. 1975 Aug;30(2):199-204. doi: 10.1128/am.30.2.199-204.1975.PMID: 809006 Free PMC article.
Products of thiocyanate oxidation by lactoperoxidase inhibit gram-positive bacteria that produce peroxide. …By the use of immobilized glucose oxidase the bacterial agent was shown to be dialyzable, destroyed by heat and counteracted, or destroyed by reducing agents …1,655Cite
Active alanine transport in isolated brush border membranes.
Sigrist-Nelson K, Murer H, Hopfer U.J Biol Chem. 1975 Jul 25;250(14):5674-80.PMID: 1141245 Free article.1,656Cite
[Effect of Brassica-like plant fodder on thiocyanate plasma and milk levels in cows].
Pyska H, Bobek S.Endokrynol Pol. 1975 Jul-Aug;26(4):409-16.PMID: 1175541 Polish. No abstract available.1,657Cite
[Effect of thiocyanate administration on milk and plasma iodine as well as thiocyanate level].
Pyska H.Endokrynol Pol. 1975 Jul-Aug;26(4):399-408.PMID: 1175540 Polish. No abstract available.1,658Cite
Chaotropic anions and the surface potential of bilayer membranes.
McLaughlin S, Bruder A, Chen S, Moser C.Biochim Biophys Acta. 1975 Jun 25;394(2):304-13. doi: 10.1016/0005-2736(75)90267-9.PMID: 166694
The chaotropic anions perchlorate and thiocyanate adsorb to artificial phospholipid membranes. The negative electrostatic potential they produce at the surface of the membranes was measured by two independent techniques. …O. (1970) J. Physiol. 207, 581-609) that thioc …1,659Cite
Maines MD, Kappas A.J Biol Chem. 1975 Jun 10;250(11):4171-7.PMID: 1126948 Free article.1,660Cite
Hopfer U.Proc Natl Acad Sci U S A. 1975 Jun;72(6):2027-31. doi: 10.1073/pnas.72.6.2027.PMID: 49051 Free PMC article.1,661Cite
Barsky EL, Bonch-Osmolovskaya EA, Ostroumov SA, Samuilov VD, Skulachev VP.Biochim Biophys Acta. 1975 May 15;387(2):388-95. doi: 10.1016/0005-2728(75)90118-8.PMID: 2360311,662Cite
Effect of thyroid status and thiocyanate on absorption and excretion of iodine by cattle.
Miller JK, Moss BR, Swanson EW, Lyke WA.J Dairy Sci. 1975 Apr;58(4):526-31. doi: 10.3168/jds.S0022-0302(75)84602-9.PMID: 1127159 Free article.
Oral thiocyanate increased urinary radioiodine 32% in throidectomized and 46% in intact calves while reducing fecal radioiodine 48% in throidectomize and 11% in intact calves. …Inhibition of gastric radioiodine secretion by thiocyanate reduced the digestive tract …1,663Cite
Hlavatý P, Augustín J, Mat’oska J, Drobnica L.Mykosen. 1975 Mar;18(3):113-7.PMID: 1134516 German. No abstract available.1,664Cite
Sudová K, Langer P.Comput Biomed Res. 1975 Feb;8(1):88-96. doi: 10.1016/0010-4809(75)90007-5.PMID: 1122750 No abstract available.1,665Cite
Leiser M, Gromet-Elhanan Z.J Biol Chem. 1975 Jan 10;250(1):84-9.PMID: 237896 Free article.
The very low level of postillumination ATP synthesis in chromatophores was markedly stimulated when permeant anions (thiocyanate or perchlorate) or permeant cations (potassium in the presence of valinomycin) were added to the light stage. …1,666Cite
Gromet-Elhanan Z, Leiser M.J Biol Chem. 1975 Jan 10;250(1):90-3.PMID: 49352 Free article.
This situation was realized when valinomycin plus KCl were added in the dark to chromatophores preilluminated above pH 6.7 with thiocyanate as the permeant anion, and the amount of ATP formed was the sum of the yields obtained with each of these affectors by itself. On the …1,667Cite
[Addition of chlorothiocyanate, dithiocyanate and iodothiocyanate to substituted chalcones].
Weber FG, Holzenger A, Westphal G, Pusch U.Pharmazie. 1975 Dec;30(12):800-1.PMID: 1219800 German. No abstract available.1,668Cite
[Investigations of the isothiocyanates erysolin and sulforaphan of Cardaria draba L].
Dornberger K, Böckel V, Heyer J, Schönfeld CH, Tonew M, Tonew E.Pharmazie. 1975 Dec;30(12):792-6.PMID: 1219798 German. No abstract available.1,669Cite
Teubner H, Weuffen W, Höppe H.Arch Exp Veterinarmed. 1975;29(4):621-9.PMID: 1190979 German.
None of the compounds tested possessed antimicrobial activity worth investigating further. However, compound No. 2 (2,4-diisothiocyanatomethyl ethoxybenzol) and compound No. 5 (1,3-dimethyl-4,6-diisothiocyanatomethylbenzol) were more active as anthelmintics against Enchytr …1,670Cite
Comparative study of abiogenesis of cysteine and other amino acids catalyzed by various metal ions.
Bahadur K, Sen P.Z Allg Mikrobiol. 1975;15(3):143-7.PMID: 1189468
The present work pertains to the study of the influence of nickel, cobalt, thorium, vanadium, molybdate, ferrous ions on the formation of cysteine which is synthesized abiogenically together with other amino acids in sterilized aqueous mixtures of ammonium thiocyanate, for …1,671Cite
Grandhi R, Brown RG, Summers JD.Poult Sci. 1975 Jan;54(1):47-53. doi: 10.3382/ps.0540047.PMID: 1135137 Free article.
At the age of four weeks the maximum uptake was only 5.58 per cent in dwarfs compared to 10.11 per cent in non-dwarf chicks. Potassium thiocyanate treatment caused a significant reduction in the uptake of iodine-131 by the thyroid glands of both 4-week-old dwarf and non-dw …1,672Cite
Antidermatophytic activity of 2-thiotetrahydro-1,3,5-thiadiazines and isothiocyanates.
Manohar V, Murthy SV, Sirsi M, Rao GR, Rao PL.J Pharm Sci. 1975 Jan;64(1):164-5. doi: 10.1002/jps.2600640140.PMID: 10941011,673Cite
Toxins and teratogens of higher plants.
Keeler RF.Lloydia. 1975 Jan-Feb;38(1):56-86.PMID: 1092947 Review. No abstract available.1,674Cite
Cohen HJ.J Clin Invest. 1975 Jan;55(1):84-93. doi: 10.1172/JCI107921.PMID: 1088910 Free PMC article.
Cap formation in these cells could not be stimulated by supplementing the energy source or protein concentration of the medium nor by adding glutamic acid which could partially reverse the vincristine and vinblastine inhibition of normal capping. The failure of agents whic …1,675Cite
Experience with bitoscanate in adults.
Patricia AH, Rao UP, Subramaniam R, Madanagopalan N.Prog Drug Res. 1975;19:90-5. doi: 10.1007/978-3-0348-7090-0_13.PMID: 769079 Clinical Trial. No abstract available.1,676Cite
Mutalik GS, Gulati RB.Prog Drug Res. 1975;19:86-9. doi: 10.1007/978-3-0348-7090-0_12.PMID: 769078 Clinical Trial. No abstract available.1,677Cite
Johnson S.Prog Drug Res. 1975;19:70-4. doi: 10.1007/978-3-0348-7090-0_9.PMID: 769076 Clinical Trial. No abstract available.1,678Cite
Thermodynamics of the unfolding of alpha-lactalbumin by guanidine thiocyanate.
Takase K, Nitta K, Sugai S.Biochim Biophys Acta. 1974 Dec 18;371(2):352-9. doi: 10.1016/0005-2795(74)90031-2.PMID: 4433571 No abstract available.1,679Cite
Delta pH and membrane potential in bacterial chromatophores.
Schuldiner S, Padan E, Rottenberg H, Gromet-Elhanan Z, Avron M.FEBS Lett. 1974 Dec 15;49(2):174-7. doi: 10.1016/0014-5793(74)80505-3.PMID: 4216516 Free article. No abstract available.1,680Cite
Deactivation of immobilized beef liver catalase by hydrogen peroxide.
Altomare RE, Kohler J, Greenfield PF, Kittrell JR.Biotechnol Bioeng. 1974 Dec;16(12):1659-73. doi: 10.1002/bit.260161208.PMID: 4441635 No abstract available.1,681Cite
Matsuzaki S, Suzuki M.Endocrinol Jpn. 1974 Dec;21(6):529-37. doi: 10.1507/endocrj1954.21.529.PMID: 4377129 Free article. No abstract available.1,682Cite
Effects of protein source, goitrogens and iodine level on performance and thyroid status of pigs.
Sihombing DT, Cromwell GL, Hays VW.J Anim Sci. 1974 Dec;39(6):1106-12. doi: 10.2527/jas1974.3961106x.PMID: 4140856 No abstract available.1,683Cite
McLaughlin PA, Nirmalan GP, Tam KH, Robinson GA.J Endocrinol. 1974 Nov;63(2):337-42. doi: 10.1677/joe.0.0630337.PMID: 4374487 No abstract available.1,684Cite
Syntheses and antimicrobial properties of isothiocyanate derivatives.
Kojima M.J Pharm Sci. 1974 Nov;63(11):1801-3. doi: 10.1002/jps.2600631135.PMID: 4214914 No abstract available.1,685Cite
Blok MC, De Gier J, Van Deenen LL.Biochim Biophys Acta. 1974 Oct 29;367(2):210-24. doi: 10.1016/0005-2736(74)90044-3.PMID: 4473216 No abstract available.1,686Cite
Raman spectroscopic study of the valinomycin–KSCN complex.
Asher IM, Rothschild KJ, Stanley HE.J Mol Biol. 1974 Oct 15;89(1):205-22. doi: 10.1016/0022-2836(74)90171-5.PMID: 4444048 No abstract available.1,687Cite
Traiger GJ, de Repentigny L, Plaa GL.Biochem Pharmacol. 1974 Oct 15;23(20):2845-56. doi: 10.1016/0006-2952(74)90059-8.PMID: 4429588 No abstract available.1,688Cite
Primary and secondary radicals in the radiation-induced inactivation of yeast alcoholdehydrogenase.
Badiello R, Tamba M, Quintiliani M.Int J Radiat Biol Relat Stud Phys Chem Med. 1974 Oct;26(4):311-9. doi: 10.1080/09553007414551291.PMID: 4611933 No abstract available.1,689Cite
Ondrejicková O, Drobnica L, Sedlácek J, Rychlík I.Biochem Pharmacol. 1974 Oct 1;23(19):2751-9. doi: 10.1016/0006-2952(74)90045-8.PMID: 4607943 No abstract available.1,690Cite
Effect of cycloheximide on the distribution of alpha-naphthylisothiocyanate in rats.
Lock S, Witschi H, Skelton FS, Hanasono G, Plaa GL.Exp Mol Pathol. 1974 Oct;21(2):237-45. doi: 10.1016/0014-4800(74)90092-6.PMID: 4413036 No abstract available.1,691Cite
Eisenbach M, Gutman M.FEBS Lett. 1974 Sep 15;46(1):368-71. doi: 10.1016/0014-5793(74)80409-6.PMID: 4423455 Free article. No abstract available.1,692Cite
Growth responses of selected quail lines to goitrogenic stresses.
Marks HL.Poult Sci. 1974 Sep;53(5):1762-8. doi: 10.3382/ps.0531762.PMID: 4138844 Free article. No abstract available.1,693Cite
Cobalt thiocyanate colorimetric determination of diphenhydramine.
Amer MM, Tawakkol MS, Ismaiel SA.Pharmazie. 1974 Aug;29(8):543-4.PMID: 4412493 No abstract available.1,694Cite
Active transport of iodide and other anions across the choroid plexus.
Wright EM.J Physiol. 1974 Aug;240(3):535-66. doi: 10.1113/jphysiol.1974.sp010622.PMID: 4369751 Free PMC article.
Ouabain, oligomycin, phloretin and 2,4-DNP inhibited the net transport of anions, but phlorrhizin, furosemide, 2,4,6-trinitro-m-cresolate, reducing agents, and antithyroid agents did not. Ouabain and phloretin were only effective on the ventricular side of the prepa …1,695Cite
Synthesis of sulfate donor in developing sea urchin embryos.
Kinoshita S.Exp Cell Res. 1974 Aug;87(2):382-5. doi: 10.1016/0014-4827(74)90495-9.PMID: 4278300 No abstract available.1,696Cite
Letter: Iodine requirements in pregnancy.
Lewis JR.Trop Doct. 1974 Jul;4(3):143.PMID: 4852834 No abstract available.1,697Cite
Burns J, Hambridge M, Taylor CR.J Clin Pathol. 1974 Jul;27(7):548-57. doi: 10.1136/jcp.27.7.548.PMID: 4607520 Free PMC article.1,698Cite
Antiparasitic thiocyanatobenzothiazoles.
Alaimo RJ, Pelosi SS.J Med Chem. 1974 Jul;17(7):775-6. doi: 10.1021/jm00253a032.PMID: 4600306 No abstract available.1,699Cite
Vainio H, Hänninen O.Acta Pharmacol Toxicol (Copenh). 1974 Jul;35(1):65-75. doi: 10.1111/j.1600-0773.1974.tb00726.x.PMID: 4210060 No abstract available.1,700Cite
Cohen WS, Bertsch W.Biochim Biophys Acta. 1974 Jun 28;347(3):371-82. doi: 10.1016/0005-2728(74)90076-0.PMID: 4135380 No abstract available.1,701Cite
The direct toxicity of alpha-naphthylisothiocyanate in cell culture.
Williams GM.Chem Biol Interact. 1974 Jun;8(6):363-9. doi: 10.1016/0009-2797(74)90042-8.PMID: 4846308 No abstract available.1,702Cite
Observations on the effects of chromate on the thyroid.
Chiraseveenuprapund P, Rosenberg IN.Endocrinology. 1974 Jun;94(6):1714-22. doi: 10.1210/endo-94-6-1714.PMID: 4364641 No abstract available.1,703Cite
Histochemical properties of the antral gastrin cell.
Larsson LI, Sundler F, Håkanson R, Grimelius L, Rehfeld JF, Stadil F.J Histochem Cytochem. 1974 Jun;22(6):419-27. doi: 10.1177/22.6.419.PMID: 4135213 No abstract available.1,704Cite
[Experimental study of the new anthelmintic jonite].
Cherniaeva AI.Med Parazitol (Mosk). 1974 May-Jun;43(3):311-4.PMID: 4459700 Russian. No abstract available.1,705Cite
Gardner LI.Pediatrics. 1974 May;53(5):813-5.PMID: 4416533 No abstract available.1,706Cite
Göckeritz D, Weuffen W, Höppe H.Pharmazie. 1974 May;29(5):339-44.PMID: 4277285 German. No abstract available.1,707Cite
The crystal structure of the NaNCS complex of nonactin.
Dobler M, Phizackerley RP.Helv Chim Acta. 1974 Apr 27;57(3):664-74. doi: 10.1002/hlca.19740570319.PMID: 4833348 No abstract available.1,708Cite
Indacochea-Redmond N, Witschi H, Plaa GL.J Pharmacol Exp Ther. 1974 Apr;189(1):278-84.PMID: 4823296 No abstract available.1,709Cite
Feldkamp CS, Palmer DJ, Salancy JA, Zak B.Z Klin Chem Klin Biochem. 1974 Apr;12(4):146-50. doi: 10.1515/cclm.1974.12.4.146.PMID: 4428836 No abstract available.1,710Cite
Teubner H, Weuffen W, Höppe H.Arch Exp Veterinarmed. 1974 Mar;28(3):249-59.PMID: 4846591 German. No abstract available.1,711Cite
Adadevoh BK, Lukanmbi FA.East Afr Med J. 1974 Mar;51(3):273-81.PMID: 4367659 No abstract available.1,712Cite
The goitrogenicity of kale and its relation to thiocyanate content.
Paxman PJ, Hill R.J Sci Food Agric. 1974 Mar;25(3):329-37. doi: 10.1002/jsfa.2740250314.PMID: 4133318 No abstract available.1,713Cite
[Propagation of intestinal parasites among the inhabitants of northwestern India].
Werner GT, Behrends R, Sareen DK, Stickl H, Wagner I.Med Klin. 1974 Feb 22;69(8):353-8.PMID: 4826684 German. No abstract available.1,714Cite
Boone DJ, Kowalsky A.Biochemistry. 1974 Feb 12;13(4):731-8. doi: 10.1021/bi00701a015.PMID: 4811063 No abstract available.1,715Cite
Single dose treatment of hookworm in Murang’a district.
Chege SW, Gitoho F, Wanene GS, Mwega VJ, Rees PH, Kinyanjui H.East Afr Med J. 1974 Jan;51(1):60-2.PMID: 4839239 Clinical Trial. No abstract available.1,716Cite
Teubner H, Weuffen W, Höppe H.Arch Exp Veterinarmed. 1974;28(2):249-59.PMID: 4478258 German. No abstract available.1,717Cite
Stickl H, Werner GT, Sareen DK.Infection. 1974;2(3):118-22. doi: 10.1007/BF01642229.PMID: 4413821 No abstract available.1,718Cite
Courtoy R, Boniver J, Simar LJ.Histochemistry. 1974;42(2):133-9. doi: 10.1007/BF00533264.PMID: 4280995 No abstract available.1,719Cite
[The specific and nonspecific defenses against infection in the bovine mammary gland].
Heeschen W, Wernery H, Tolle A, Korhonen H.Zentralbl Bakteriol Orig A. 1974;227(1-4):236-48.PMID: 4154592 German. No abstract available.1,720Cite
The interaction of chaotropic anions with proteins at acid pH.
Aviram I.Eur J Biochem. 1973 Dec 17;40(2):631-6. doi: 10.1111/j.1432-1033.1973.tb03235.x.PMID: 4592653 Free article. No abstract available.1,721Cite
Chloride-dependent uncoupling mediated by oligomycin in rat liver mitochondria.
Ariel N, Avi-Dor Y.Biochem J. 1973 Dec;136(4):911-7. doi: 10.1042/bj1360911.PMID: 4274378 Free PMC article.1,722Cite
Jonit in the treatment of hymenolepiasis: a new drug by cyclic regimen.
Bhandari B, Upadhyay R, Shrimali LN, Agarwal SS.Indian Pediatr. 1973 Nov;10(11):675-7.PMID: 4793393 No abstract available.1,723Cite
A preliminary study on the action of cassava on thyroid iodine metabolism in rats.
Van der Velden M, Kinthaert J, Orts S, Ermans AM.Br J Nutr. 1973 Nov;30(3):511-7. doi: 10.1079/bjn19730057.PMID: 4127199 No abstract available.1,724Cite
Norris DO, Platt JE.Gen Comp Endocrinol. 1973 Oct;21(2):368-76. doi: 10.1016/0016-6480(73)90069-5.PMID: 4753365 No abstract available.1,725Cite
[Organic synthesis of thiocyanate compounds. No. 46, Part 2. Aliphatic thiocyanate compounds].
Knoke D, Kottke K, Pohloudek-Fabini R.Pharmazie. 1973 Oct;28(10):617-32.PMID: 4593387 Review. German. No abstract available.1,726Cite
Iodine deficiency, environmental goitrogens and genetic factors in the etiology of endemic goiter.
Podoba J, Michajlovskij M, Stukovsky R.Acta Endocrinol Suppl (Copenh). 1973 Oct;179:36-7.PMID: 4523771 No abstract available.1,727Cite
Ermans AM, Delange F, Van der Velden M, Kinthaert J.Acta Endocrinol Suppl (Copenh). 1973 Oct;179:31.PMID: 4523769 No abstract available.1,728Cite
Nicholls DG, Lindberg O.Eur J Biochem. 1973 Sep 3;37(3):523-30. doi: 10.1111/j.1432-1033.1973.tb03014.x.PMID: 4777251 Free article. No abstract available.1,729Cite
The b cytochromes in succinate–cytochrome c reductase from pigeon breast mitochondria.
Erecińska M, Oshino R, Oshino N, Chance B.Arch Biochem Biophys. 1973 Aug;157(2):431-45. doi: 10.1016/0003-9861(73)90659-0.PMID: 4354319 No abstract available.1,730Cite
A goitrous subject with defective synthesis of diiodotyrosine due to thyroglobulin abnormalities.
Kusakabe T.J Clin Endocrinol Metab. 1973 Aug;37(2):317-25. doi: 10.1210/jcem-37-2-317.PMID: 4198258 No abstract available.1,731Cite
Transfer of anions across phospholipid membranes.
Singer MA.Can J Physiol Pharmacol. 1973 Jul;51(7):523-31. doi: 10.1139/y73-077.PMID: 4738312 No abstract available.1,732Cite
Gattereau A, Bénard B, Verdy M, Bellabarba D, Brun D.J Clin Endocrinol Metab. 1973 Jul;37(1):118-28. doi: 10.1210/jcem-37-1-118.PMID: 4200219 No abstract available.1,733Cite
Purification and characterization of two proteins with co-lipase activity from porcine pancreas.
Erlanson C, Fernlund P, Borgström B.Biochim Biophys Acta. 1973 Jun 15;310(2):437-45. doi: 10.1016/0005-2795(73)90127-x.PMID: 4737019 No abstract available.1,734Cite
[The modification of a potassium thiocyanate test for the differentiation of enterococci–RM-test].
Skorkovský B.Zentralbl Bakteriol Orig A. 1973 Jun;224(1):71-6.PMID: 4126165 German. No abstract available.1,735Cite
Preparation and properties of lysozyme modified by fluorescein-isothiocyanate.
Hiramatsu M, Okabe N, Tomita K.J Biochem. 1973 May;73(5):971-8. doi: 10.1093/oxfordjournals.jbchem.a130181.PMID: 4721777 Free article. No abstract available.1,736Cite
Lack of thyroid peroxidase activity as the cause of congenital goitrous hypothyroidism.
Valenta LJ, Bode H, Vickery AL, Caulfield JB, Maloof F.J Clin Endocrinol Metab. 1973 May;36(5):830-44. doi: 10.1210/jcem-36-5-830.PMID: 4698243 No abstract available.1,737Cite
Roushdi IM, Ibrahim el-SA, Beltagy YA, Issa A.Pharmazie. 1973 Apr;28(4):236-7.PMID: 4716604 No abstract available.1,738Cite
Permeability of Azotobacter vinelandii to cations and anions.
Visser AS, Postma PW.Biochim Biophys Acta. 1973 Mar 16;298(2):333-40. doi: 10.1016/0005-2736(73)90362-3.PMID: 4198137 No abstract available.1,739Cite
A new anthelmintic for the treatment of hookworm disease.
Ghouri MA, Sama SK, Das Gupta LR, Chuttani HK.J Assoc Physicians India. 1973 Mar;21(3):291-3.PMID: 4792778 No abstract available.1,740Cite
[Goitrogenic activity of turnip: experimental study in rats (author’s transl)].
Muñoz-Rodríguez M, García de Jalón J.Rev Esp Fisiol. 1973 Mar;29(1):21-6.PMID: 4749043 Spanish. No abstract available.1,741Cite
Indacochea-Redmond N, Witschi H, Plaa GL.J Pharmacol Exp Ther. 1973 Mar;184(3):780-6.PMID: 4687237 No abstract available.1,742Cite
[Bitoscanate: a new anthelmintic].
Chodera L, Chwirot E, Pawlowski Z, Skrzypińska K.Pol Tyg Lek. 1973 Feb 26;28(9):338-40.PMID: 4693304 Polish. No abstract available.1,743Cite
Kragh-Hansen U, Moller JV.Biochim Biophys Acta. 1973 Feb 21;295(2):438-46.PMID: 4573078 No abstract available.1,744Cite
A peroxidase-mediated, streptococcus mitis-dependent antimicrobial system in saliva.
Hamon CB, Klebanoff SJ.J Exp Med. 1973 Feb 1;137(2):438-50. doi: 10.1084/jem.137.2.438.PMID: 4685704 Free PMC article.
The H(2)O(2) formed by S. mitis could be employed as a component of an antimicrobial system that also included lactoperoxidase (LPO) and either iodide or thiocyanate ions in the concentrations present in saliva. …The antimicrobial effect of the LPO-thioc …1,745Cite
Carbon framework of valinomycin and its metal ion complex in solution.
Patel DJ.Biochemistry. 1973 Jan 30;12(3):496-501. doi: 10.1021/bi00727a021.PMID: 4683492 No abstract available.1,746Cite
Dihydrofolate reductases of Escherichia coli and bacteriophage Tr. A spectrofluorometric study.
Erickson JS, Mathews CK.Biochemistry. 1973 Jan 30;12(3):372-80. doi: 10.1021/bi00727a002.PMID: 4405201 No abstract available.1,747Cite
Trial of phenylen di-isothiocyanate (Joint) in the mass-treatment of intestinal helminthiasis.
Arfaa F, Sahba GH, Jamshidi C, Jalali H.Bull Soc Pathol Exot Filiales. 1973 Jan-Feb;66(1):191-5.PMID: 4801784 No abstract available.1,748Cite
Kozlowski M, Kozlowska H, Rutkowski A.Nahrung. 1973;17(2):147-52.PMID: 4794643 German. No abstract available.1,749Cite
[Pendred’s syndrome in Dakar (apropos of 5 cases)].
Cuisinier JC, Ferro R, Cazaubon J, Varieras G, Ducloux M, Perquis P.Bull Soc Med Afr Noire Lang Fr. 1973;18(3):373-81.PMID: 4784677 French. No abstract available.1,750Cite
Thyroidal 131 I uptake of Japanese quail in response to three different dietary goitrogens.
Howarth B Jr, Marks HL.Poult Sci. 1973 Jan;52(1):326-31. doi: 10.3382/ps.0520326.PMID: 4709771 Free article. No abstract available.1,751Cite
Roberts RJ.Proc Soc Exp Biol Med. 1973 Jan;142(1):365-7. doi: 10.3181/00379727-142-37023.PMID: 4683260 No abstract available.1,752Cite
van Boxtel CJ, Engelfriet CP, Feltkamp TE.Scand J Immunol. 1973;2(3):217-29. doi: 10.1111/j.1365-3083.1973.tb02032.x.PMID: 4588995 No abstract available.1,753Cite
Hoogendoorn H, Moorer WR.Odontol Revy. 1973;24(4):355-66.PMID: 4522274 No abstract available.1,754Cite
Bobek S, Kahl S.Endokrynol Pol. 1973 Jan-Feb;24(1):21-31.PMID: 4348694 Polish. No abstract available.1,755Cite
[Immune regulatory effects of methenamine hydrorhodanide (Rhodovet)].
Jülich W-D, Bohnenstengel C, Klatt W.Allerg Immunol (Leipz). 1973;19(2-4):173-7.PMID: 4281619 German. No abstract available.1,756Cite
Hasilik A.Z Naturforsch C. 1973 Jan-Feb;28(1):21-31. doi: 10.1515/znc-1973-1-205.PMID: 4148805 No abstract available.1,757Cite
Iwarsson K, Nilsson PO.Acta Vet Scand. 1973;14(4):595-609.PMID: 4127863 No abstract available.1,758Cite
Iwarsson K.Acta Vet Scand. 1973;14(4):570-94.PMID: 4127862 No abstract available.1,759Cite
Primary structures of the proinsulin connecting peptides of the rat and the horse.
Tager HS, Steiner DF.J Biol Chem. 1972 Dec 25;247(24):7936-40.PMID: 4640931 Free article. No abstract available.1,760Cite
[Formation and antiviral effect of N-(adamantyl-91))-thiocarbamides].
Kreutzberger A, Schröders HH.Arch Pharm (Weinheim). 1972 Dec;305(12):907-13. doi: 10.1002/ardp.19723051206.PMID: 4663592 German. No abstract available.1,761Cite
Reagent-impregnated paper strip for detection of metabolic products of isoniazid in urine.
Kilburn JO, Beam RE, David HL, Sanchez E, Corpe RF, Dunn W.Am Rev Respir Dis. 1972 Dec;106(6):923-4. doi: 10.1164/arrd.1972.106.6.923.PMID: 4641228 No abstract available.1,762Cite
Krigbaum WR, Kuegler FR, Oelschlaeger H.Biochemistry. 1972 Nov 21;11(24):4548-52. doi: 10.1021/bi00774a018.PMID: 4654142 No abstract available.1,763Cite
Mutalik GS, Gulati RB.Indian J Med Sci. 1972 Nov;26(11):718-22.PMID: 4654414 Clinical Trial. No abstract available.1,764Cite
Goldsmid JM, MacCabe RJ.Cent Afr J Med. 1972 Nov;18(11):227-9.PMID: 4591914 Clinical Trial. No abstract available.1,765Cite
Vainio H, Baltscheffsky M, Baltscheffsky H, Azzi A.Eur J Biochem. 1972 Oct;30(2):301-6. doi: 10.1111/j.1432-1033.1972.tb02098.x.PMID: 4351437 Free article. No abstract available.1,766Cite
[Effect of abnormal anions upon frog striated muscular fiber, detubulated by osmotic shock].
Louis-Schauer H, Mandrino M.J Physiol (Paris). 1972 Oct;65:Suppl:267A.PMID: 4346484 French. No abstract available.1,767Cite
Hepatomegaly: parameter of chronic experimental drug toxicity.
Sethi N, Talwalkar V, Mukherjee SK.Indian J Physiol Pharmacol. 1972 Oct-Dec;16(4):339-43.PMID: 4145782 No abstract available.1,768Cite
O’Holohan DR, Hugoe-Matthews J.Southeast Asian J Trop Med Public Health. 1972 Sep;3(3):403-10.PMID: 4652468 No abstract available.1,769Cite
Nimberg RB, Schmid K.J Biol Chem. 1972 Aug 25;247(16):5056-61.PMID: 4115806 Free article. No abstract available.1,770Cite
Papa S, Scarpa A, Lee CP, Chance B.Biochemistry. 1972 Aug 1;11(16):3091-8. doi: 10.1021/bi00766a024.PMID: 5041914 No abstract available.1,771Cite
Gromet-Elhanan Z.Biochim Biophys Acta. 1972 Jul 12;275(1):125-9. doi: 10.1016/0005-2728(72)90032-1.PMID: 4340267 No abstract available.1,772Cite
Isolation and characterization of discrete fragments of 27 S thyroid iodoprotein.
Bilstad JM, Edelhoch H, Lippoldt R, Rall JE, Salvatore G.Arch Biochem Biophys. 1972 Jul;151(1):341-50. doi: 10.1016/0003-9861(72)90505-x.PMID: 5044523 No abstract available.1,773Cite
Antamanide and analogs. Studies on selectivity and stability of complexes.
Wieland T, Faulstich H, Burgermeister W.Biochem Biophys Res Commun. 1972 Jun 9;47(5):984-92. doi: 10.1016/0006-291x(72)90929-1.PMID: 4337749 No abstract available.1,774Cite
Düwel D.Southeast Asian J Trop Med Public Health. 1972 Jun;3(2):229-34.PMID: 5082851 No abstract available.1,775Cite
Endemic goiter in Sarawak, Borneo Island; prevalence and pathogenesis.
Ogihara T, Oki K, Iida Y, Hayashi S.Endocrinol Jpn. 1972 Jun;19(3):285-93. doi: 10.1507/endocrj1954.19.285.PMID: 4117947 Free article. No abstract available.1,776Cite
Amino-terminal sequence analysis of proteins purified on a nanomole scale by gel electrophoresis.
Weiner AM, Platt T, Weber K.J Biol Chem. 1972 May 25;247(10):3242-51.PMID: 4112808 Free article. No abstract available.1,777Cite
Denaturation of globular proteins. Interaction of guanidinium salts with three proteins.
Gordon JA.Biochemistry. 1972 May 9;11(10):1862-70. doi: 10.1021/bi00760a021.PMID: 5063539 No abstract available.1,778Cite
Solubility of amino acids in aqueous guanidinium thiocyanate solutions.
Dooley KH, Castellino FJ.Biochemistry. 1972 May 9;11(10):1870-4. doi: 10.1021/bi00760a022.PMID: 5025628 No abstract available.1,779Cite
Nucleotide-peptides of cells of the Ehrlich-Lettré ascites carcinoma.
Islam MN, Kay ER.Arch Biochem Biophys. 1972 May;150(1):250-8. doi: 10.1016/0003-9861(72)90033-1.PMID: 5063703 No abstract available.1,780Cite
Bangham AD.Chem Phys Lipids. 1972 May;8(4):386-92. doi: 10.1016/0009-3084(72)90069-2.PMID: 5041948 No abstract available.1,781Cite
McVeigh I, Evans S, Field L, Hanley WS, Tate CE.J Med Chem. 1972 Apr;15(4):431-3. doi: 10.1021/jm00274a033.PMID: 5019569 No abstract available.1,782Cite
Patel KM, Olweny CL.East Afr Med J. 1972 Apr;49(4):270-2.PMID: 4559712 Clinical Trial. No abstract available.1,783Cite
Hasilík A, Livar M.Chem Biol Interact. 1972 Apr;4(5):305-10. doi: 10.1016/0009-2797(72)90084-1.PMID: 4400387 No abstract available.1,784Cite
The influence of permeant anions upon mitochondrial energy conservation by means of a K + gradient.
Cockrell RS.Biochem Biophys Res Commun. 1972 Mar 24;46(6):1991-8. doi: 10.1016/0006-291x(72)90749-8.PMID: 5018663 No abstract available.1,785Cite
A single dose of Jonit in the treatment of human ancylostomiasis.
Holz J, Adhman D, Gunardi AT, Murad S, Sadeli OR, Wuisan JO.Southeast Asian J Trop Med Public Health. 1972 Mar;3(1):99-102.PMID: 5028868 No abstract available.1,786Cite
Chitrathorn S, Acalabol M, Thongkong M, Kamolsin C.Southeast Asian J Trop Med Public Health. 1972 Mar;3(1):103-5.PMID: 5028855 No abstract available.1,787Cite
Failure to detect cell-associated enterotoxin B in Staphylococcus aureus by immunofluorescence.
Forsgren A, Forsum U, Hallander HO.Appl Microbiol. 1972 Mar;23(3):559-64. doi: 10.1128/am.23.3.559-564.1972.PMID: 4623281 Free PMC article.1,788Cite
Adams GE, Aldrich JE, Bisby RH, Cundall RB, Redpath JL, Willson RL.Radiat Res. 1972 Feb;49(2):278-89.PMID: 5058070 No abstract available.1,789Cite
Zinner G, Lüpke NP, Dybowski U.Arch Pharm (Weinheim). 1972 Jan;305(1):64-70. doi: 10.1002/ardp.19723050112.PMID: 5060416 German. No abstract available.1,790Cite
On the existence of lipid peroxides in rat tissue.
Glavind J.Br J Nutr. 1972 Jan;27(1):19-26. doi: 10.1079/bjn19720065.PMID: 5059382 No abstract available.1,791Cite
Komeichi Y, Iwasaki T, Ito Y, Aida F.Steroids. 1972 Jan;19(1):47-58. doi: 10.1016/0039-128x(72)90026-8.PMID: 5021417 No abstract available.1,792Cite
Effect of ether anesthesia on circulating insulin levels of rats on different goitrogens.
Jolin T.Hormones. 1972;3(1):31-5. doi: 10.1159/000178255.PMID: 4654623 No abstract available.1,793Cite
Jolin T, Nuñez J, Mora RJ.Hormones. 1972;3(4):228-34. doi: 10.1159/000178273.PMID: 4653181 No abstract available.1,794Cite
The equivalent pore radius of intact and damaged mitochondria and the mechanism of active shrinkage.
Massari S, Azzone GF.Biochim Biophys Acta. 1972;283(1):23-9. doi: 10.1016/0005-2728(72)90094-1.PMID: 4643353 No abstract available.1,795Cite
Possible role of cyanide and thiocyanate in the etiology of endemic cretinism.
Ermans AM, Delange F, Van der Velden M, Kinthaert J.Adv Exp Med Biol. 1972;30:455-86.PMID: 4582012 Review. No abstract available.1,796Cite
The chemotherapy of intestinal nematodes.
McFarland JW.Prog Drug Res. 1972;16:157-93. doi: 10.1007/978-3-0348-7081-8_3.PMID: 4567339 Review. No abstract available.1,797Cite
Molecular basis of insulin action: contributions of chemical modifications and synthetic approaches.
Zahn H, Brandenburg D, Gattner HG.Diabetes. 1972;21(2 Suppl):468-75. doi: 10.2337/diab.21.2.s468.PMID: 4559915 No abstract available.1,798Cite
Sudová K, Langer P.Physiol Bohemoslov. 1972;21(5):511-6.PMID: 4266219 No abstract available.1,799Cite
Proceedings: Differential media for the isolation of Listeria monocytogenes.
Khan MA, Seaman A, Woodbine M.Acta Microbiol Acad Sci Hung. 1972;19(4):371-2.PMID: 4206777 No abstract available.1,800Cite
Proceedings: Methods to isolate Listeria monocytogenes from different materials.
Ralovich B, Emödy L, Málovics I, Mérö E, Forray A.Acta Microbiol Acad Sci Hung. 1972;19(4):367-9.PMID: 4206776 No abstract available.
Mashita K, Suzuki K.Nihon Rinsho. 1972 Jan;30(1):307-10.PMID: 4114166 Review. Japanese. No abstract available.1,802Cite
Eklund A, Agren G, Langler T.J Sci Food Agric. 1971 Dec;22(12):650-2. doi: 10.1002/jsfa.2740221212.PMID: 5139821 No abstract available.1,803Cite
Kulbe KD.Anal Biochem. 1971 Dec;44(2):548-58. doi: 10.1016/0003-2697(71)90244-2.PMID: 5130945 No abstract available.1,804Cite
Spivak VA, Levjant MI, Katrukha SP, Varshavsky JM.Anal Biochem. 1971 Dec;44(2):503-18. doi: 10.1016/0003-2697(71)90238-7.PMID: 5002191 No abstract available.1,805Cite
Lee C.Biochemistry. 1971 Nov 23;10(24):4375-81. doi: 10.1021/bi00800a004.PMID: 4335085 No abstract available.1,806Cite
Effects of anions on sodium transport in toad urinary bladder.
Singer I, Civan MM.Am J Physiol. 1971 Oct;221(4):1019-26. doi: 10.1152/ajplegacy.1971.221.4.1019.PMID: 4999967 No abstract available.1,807Cite
Lapanje S.Biochim Biophys Acta. 1971 Sep 28;243(3):357-65. doi: 10.1016/0005-2795(71)90002-x.PMID: 5166998 No abstract available.1,808Cite
Lapanje S.Biochim Biophys Acta. 1971 Sep 28;243(3):349-56. doi: 10.1016/0005-2795(71)90001-8.PMID: 5001983 No abstract available.1,809Cite
Rotational relaxation time of pyridoxyl 5-phosphate lysozyme.
Irwin R, Churchich JE.J Biol Chem. 1971 Sep 10;246(17):5329-34.PMID: 5094672 Free article. No abstract available.1,810Cite
Respiration-driven proton translocation in Micrococcus denitrificans.
Scholes P, Mitchell P.J Bioenerg. 1971 Sep;1(3):309-23. doi: 10.1007/BF01516290.PMID: 5135306 No abstract available.1,811Cite
Effect of freezing in methylmercaptoimidazole on the structure of thyroglobulin.
Cramarossa L, Andreoli M, Schneider A, Edelhoch H.Endocrinology. 1971 Sep;89(3):741-8. doi: 10.1210/endo-89-3-741.PMID: 4105306 No abstract available.1,812Cite
Polysaccharides in germination. Xyloglucans ( amyloids’) from the cotyledons of white mustard.
Gould SE, Rees DA, Wight NJ.Biochem J. 1971 Aug;124(1):47-53. doi: 10.1042/bj1240047.PMID: 5001672 Free PMC article.
Two xyloglucan fractions have been isolated from the cotyledons of resting white-mustard seeds, the first by extraction with hot EDTA, and the second by subsequent extraction with alkali or lithium thiocyanate. Although both appear to have the ;amyloid’ type of structure i …1,813Cite
Langer P.J Endocrinol. 1971 Jul;50(3):367-72. doi: 10.1677/joe.0.0500367.PMID: 5558045 No abstract available.1,814Cite
Inhibition of virus multiplication by selected isothiocyanates.
Rada B, Hanusovská T, Drobnica L, Nĕmec P.Acta Virol. 1971 Jul;15(4):329-32.PMID: 4398087 No abstract available.1,815Cite
Johnson SC.J Trop Med Hyg. 1971 Jun;74(6):133-6.PMID: 5580869 No abstract available.1,816Cite
Keen P, White TD.J Neurochem. 1971 Jun;18(6):1097-103. doi: 10.1111/j.1471-4159.1971.tb12038.x.PMID: 5567898 No abstract available.1,817Cite
Tezuka U, Murakami T, Mishiro K, Fujino M, Takeichi O.Endocrinol Jpn. 1971 Jun;18(3):267-79. doi: 10.1507/endocrj1954.18.267.PMID: 5172024 Free article. No abstract available.1,818Cite
Pressman BC.Neurosci Res Program Bull. 1971 Jun;9(3):320-30.PMID: 5164650 No abstract available.1,819Cite
Katiyar JC, Sen AB.Indian J Med Res. 1971 Jun;59(6):949-56.PMID: 5121773 No abstract available.1,820Cite
Improved method for the determination of iodine in urine.
Mantel M.Clin Chim Acta. 1971 Jun;33(1):39-44. doi: 10.1016/0009-8981(71)90246-4.PMID: 5098012 No abstract available.1,821Cite
Spira O, Gordon A, Gross J.Acta Endocrinol (Copenh). 1971 Jun;67(2):241-8.PMID: 4325331 No abstract available.1,822Cite
[New ways of conservative treatment of bladder neck diseases].
Massier J.Wien Klin Wochenschr. 1971 May 14;83(19):337-8.PMID: 4104107 German. No abstract available.1,823Cite
Imai Y, Siekevitz P.Arch Biochem Biophys. 1971 May;144(1):143-59. doi: 10.1016/0003-9861(71)90464-4.PMID: 5117524 No abstract available.1,824Cite
Hamada Y, Matsuoka H, Fukatsu H.Yakugaku Zasshi. 1971 May;91(5):565-70. doi: 10.1248/yakushi1947.91.5_565.PMID: 5105142 Japanese. No abstract available.1,825Cite
Nakajima H, Niimi H, Fujimori M.Endocrinol Jpn. 1971 Apr;18(2):205-10. doi: 10.1507/endocrj1954.18.205.PMID: 4998425 Free article. No abstract available.1,826Cite
[Clonorchiasis and its treatment with a new anthelmintic agents].
Mohr W, Merkle F.Med Klin. 1971 Mar 13;65(11):515-8.PMID: 5104563 German. No abstract available.1,827Cite
Comparative efficacy of iodothymol in a field trial.
Gaitonde BB, Koti ST, Toraskar DB, Kulkarni HJ, Kamat RA.J Assoc Physicians India. 1971 Mar;19(3):267-71.PMID: 5558809 No abstract available.1,828Cite
O’Holohan DR, Hugoe-Matthews J, Kanagasabai K.Southeast Asian J Trop Med Public Health. 1971 Mar;2(1):51-5.PMID: 5112340 No abstract available.1,829Cite
Epshteĭn IaA.Dokl Akad Nauk SSSR. 1971 Mar 1;197(1):227-9.PMID: 5089649 Russian. No abstract available.1,830Cite
Prompt stimulation by TSH of thyroid oxidation of thiocyanate.
Otaki S, Rosenberg IN.Endocrinology. 1971 Mar;88(3):566-73. doi: 10.1210/endo-88-3-566.PMID: 4322381 No abstract available.1,831Cite
Makarevich VG, Gaziian NR.Antibiotiki. 1971 Jan;16(1):22-7.PMID: 5553272 Russian. No abstract available.1,832Cite
Trial of phenylene-di-iso-thiocyanate (1,4), on Anyclostoma duodenale infection.
Ata AA, Sheir ZM, Amer ZM.J Egypt Med Assoc. 1971;54(2):177-80.PMID: 5156458 No abstract available.1,833Cite
Clinical trials of phenylene-diiso-thiocyanate (1,4) in the treatment of ancylostomiasis.
el-Haway AM, Mousa AH, el-Garem AA, Ekram AA.J Egypt Med Assoc. 1971;54(2):171-6.PMID: 5156457 No abstract available.1,834Cite
[Clinical evaluation of phenylene-di-iso-thyocyanate (Jonit + Hoechst) in ancylostomiasis].
Huggins D.An Esc Nacl Saude Publica Med Trop (Lisb). 1971 Jan-Jun;5(1):33-7.PMID: 5138869 Portuguese. No abstract available.1,835Cite
Clinical trials with compound L6842, a new anthelminthic agent.
Shafei AZ, Abaza HH, Hammouda N, Elgohary Y.J Egypt Med Assoc. 1971;54(5):361-75.PMID: 5131174 No abstract available.1,836Cite
Wildführ W, Franz H.Zentralbl Bakteriol Orig. 1971;216(4):532-40.PMID: 4932523 German. No abstract available.1,837Cite
Zsolnai T.Arzneimittelforschung. 1971 Jan;21(1):121-7.PMID: 4929243 German. No abstract available.1,838Cite
[Struma medicamentosa–a survey].
Kleint V.Z Gesamte Inn Med. 1971 Jan 1;26(1):1-11.PMID: 4336748 Review. German. No abstract available.1,839Cite
Oxidation of thiocyanate to cyanide and sulfate by the lactoperoxidase-hydrogen peroxide system.
Chung J, Wood JL.Arch Biochem Biophys. 1970 Nov;141(1):73-8. doi: 10.1016/0003-9861(70)90108-6.PMID: 5480127 No abstract available.1,840Cite
Evidence for the presence of two thiocyanate-dependent antibacterial systems in human saliva.
Dogon IL, Amdur BH.Arch Oral Biol. 1970 Oct;15(10):987-92. doi: 10.1016/0003-9969(70)90094-4.PMID: 5275753 No abstract available.1,841Cite
The source of H2O2 for the uterine fluid-mediated sperm-inhibitory system.
Klebanoff SJ, Smith DC.Biol Reprod. 1970 Oct;3(2):236-42. doi: 10.1093/biolreprod/3.2.236.PMID: 5001780 No abstract available.1,842Cite
Hsieh HC, Chen CY, Yii CY, Chen MH, Hong JM.Taiwan Yi Xue Hui Za Zhi. 1970 Aug 28;69(8):405-9.PMID: 5274231 No abstract available.1,843Cite
Effects of trialkyltin and triphenyltin compounds on mitochondrial respiration.
Stockdale M, Dawson AP, Selwyn MJ.Eur J Biochem. 1970 Aug;15(2):342-51. doi: 10.1111/j.1432-1033.1970.tb01013.x.PMID: 5502666 Free article. No abstract available.1,844Cite
Lämmler G, Srivastava VK, Zahner H.Br Vet J. 1970 Aug;126(8):427-39. doi: 10.1016/s0007-1935(17)48251-0.PMID: 5485196 No abstract available.1,845Cite
Thyroid function in sibships in endemic goiter region.
Podoba J, Stukovský R, Kovac R.J Clin Endocrinol Metab. 1970 Aug;31(2):134-9. doi: 10.1210/jcem-31-2-134.PMID: 4194165 No abstract available.1,846Cite
Poisner AM, Hava M.Mol Pharmacol. 1970 Jul;6(4):407-15.PMID: 4246825 No abstract available.1,847Cite
Jolin T, Morreale de Escobar G, Escobar del Rey F.Endocrinology. 1970 Jul;87(1):99-110. doi: 10.1210/endo-87-1-99.PMID: 4192261 No abstract available.1,848Cite
Thiocyanato-indoles as energy-transfer inhibitors in photophosphorylation.
Brandon PC.Arch Biochem Biophys. 1970 Jun;138(2):655-73. doi: 10.1016/0003-9861(70)90382-6.PMID: 4393556 No abstract available.1,849Cite
Fluorescence quenching and conformational changes of proteins.
Arrio B, Rodier F, Boisson C, Vernotte C.Biochem Biophys Res Commun. 1970 May 22;39(4):589-93. doi: 10.1016/0006-291x(70)90244-5.PMID: 5530902 No abstract available.1,850Cite
[Studies on chemotherapeutics. V. Nematocidal activities of azo and diphenylether compounds].
Hamada Y, Matsuoka H, Hayashi M.Yakugaku Zasshi. 1970 May;90(5):644-6.PMID: 5464197 Japanese. No abstract available.1,851Cite
Demetrescu C, Manu V, Chirită C.Pharmazie. 1970 May-Jun;25(5):317-9.PMID: 5455410 German. No abstract available.1,852Cite
The antibacterial action of lactoperoxidase. The nature of the bacterial inhibitor.
Hogg DM, Jago GR.Biochem J. 1970 May;117(4):779-90. doi: 10.1042/bj1170779.PMID: 5449131 Free PMC article.
Lactoperoxidase (EC 1.11.1.7), an enzyme present in various mammalian glands and in their secretions, catalyses the oxidation of thiocyanate by hydrogen peroxide to form a compound that inhibits the growth, oxygen uptake and acid production of certain bacteria. …The inhi …1,853Cite
Clinical evaluation of a new drug for the treatment of ancylostomiasis.
Botero D, Perez A.Am J Trop Med Hyg. 1970 May;19(3):471-5. doi: 10.4269/ajtmh.1970.19.471.PMID: 4911015 Clinical Trial. No abstract available.1,854Cite
Hogg DM, Jago GR.Biochem J. 1970 May;117(4):791-7. doi: 10.1042/bj1170791.PMID: 4317722 Free PMC article.
Lactoperoxidase (EC 1.11.1.7) catalysed the oxidation of NADH by hydrogen peroxide in the presence of either thiocyanate, iodide or bromide. In the presence of thiocyanate, net oxidation of thiocyanate occurred simultaneously with the oxidation of NADH, but i …1,855Cite
Hatefi Y, Hanstein WG.Arch Biochem Biophys. 1970 May;138(1):73-86. doi: 10.1016/0003-9861(70)90286-9.PMID: 4315697 No abstract available.1,856Cite
[Clinico-experimental study of the effect of the goitrogenic effect thiocyanante].
Muñoz-Rodríguez M, García de Jalón J.Rev Esp Fisiol. 1970 Mar;26(1):53-60.PMID: 5431813 Spanish. No abstract available.1,857Cite
[Work hygiene when using carbathion for sterilizing hothouses].
Nesterova MF.Gig Tr Prof Zabol. 1970 Mar;14(3):44-6.PMID: 4247699 Russian. No abstract available.1,858Cite
Peroxidatic activity of catalase.
Kremer ML.Biochim Biophys Acta. 1970 Feb 11;198(2):199-209. doi: 10.1016/0005-2744(70)90052-5.PMID: 5461226 No abstract available.1,859Cite
[Various pharmacological aspects of 2-phenyl-2-ethyl-4-thiocyano-glutarimide].
Arrabito R, Ferappi M.Boll Chim Farm. 1970 Feb;109(2):127-31.PMID: 5454980 Italian. No abstract available.1,860Cite
Action of SCN- on rat liver mitochondria.
Sachs G, Collier RH, Hirschowitz BI.Proc Soc Exp Biol Med. 1970 Feb;133(2):456-9. doi: 10.3181/00379727-133-34496.PMID: 5414229 No abstract available.1,861Cite
Dedek W, Wenzel KD, Grahl R.Z Naturforsch B. 1970 Feb;25(2):217-9.PMID: 4393444 German. No abstract available.1,862Cite
Dedek W, Grahl R, Schwarz H, Liebaug E.Z Naturforsch B. 1970 Feb;25(2):219-20.PMID: 4392890 German. No abstract available.1,863Cite
[Pathophysiology and clinical aspects of intrahepatic cholestasis].
Kühn HA, Richter E.Med Klin. 1970 Jan 2;65(1):1-8.PMID: 4929317 Review. German. No abstract available.1,864Cite
Janke J, Oberdisse A, Petzoldt C.Pflugers Arch. 1970;314(2):124-40. doi: 10.1007/BF00587197.PMID: 5460707 German. No abstract available.1,865Cite
[Role of biotin in the metabolism process of Streptomyces aureofaciens].
Shulo Sh, Zelinka Ia.Mikrobiologiia. 1970 Jan-Feb;39(1):5-10.PMID: 5451438 Russian. No abstract available.1,866Cite
[Resorption kinetics of 4-bromophenylisothiocyanate-35S in guinea-pig skin].
Augustín J, Hlavatý P, Valentová M, Drobnica L.Arch Klin Exp Dermatol. 1970;238(1):1-9.PMID: 5421919 German. No abstract available.1,867Cite
A simple micromethod for the determination of total iron in whole blood.
Dawes RL, Park C.J Med Lab Technol. 1970 Jan;27(1):55-7.PMID: 5412555 No abstract available.1,868Cite
[Antiparasitic effect of a new therapeutic drug in uncinariasis].
Canal Feijoo EJ.Prensa Med Argent. 1969 Dec 19;56(42):1858-63.PMID: 5375965 Spanish. No abstract available.1,869Cite
Clinical evaluation of diphenylsulphone-4:4′-diiso-thiocyanate against tapeworms in dogs and fowls.
Katiyar JC, Sen AB.Indian Vet J. 1969 Dec;46(12):1043-6.PMID: 5393515 No abstract available.1,870Cite
Cromwell LD, Stark GR.Biochemistry. 1969 Dec;8(12):4735-40. doi: 10.1021/bi00840a012.PMID: 4904040 No abstract available.1,871Cite
[Antiparasitic activity of compound 16,842 in uncinariasis and trichocephaliasis].
Biagi F, Zavala J, Malagon F.Rev Inst Med Trop Sao Paulo. 1969 Nov-Dec;11(6):444-8.PMID: 5372719 Spanish. No abstract available.1,872Cite
Outbreak of superficial keratitis in rubber workers.
Groves JS, Smail JM.Br J Ophthalmol. 1969 Oct;53(10):683-7. doi: 10.1136/bjo.53.10.683.PMID: 5347168 Free PMC article. No abstract available.1,873Cite
Gaitonde BB, Kulkarni HJ, Kamat RA, Vakil BJ.J Trop Med Hyg. 1969 Oct;72(10):253-8.PMID: 4900620 Clinical Trial. No abstract available.1,874Cite
Clinical trial of bitoscanate in hookworm disease.
Mutalik GS, Gulati RB.Clin Pharmacol Ther. 1969 Sep-Oct;10(5):635-7. doi: 10.1002/cpt1969105635.PMID: 5808459 No abstract available.1,875Cite
The kinetics of the inhibition of thyroidal iodide accumulation by thiocyanate: a reexamination.
Scranton JR, Nissen WM, Halmi NS.Endocrinology. 1969 Sep;85(3):603-7. doi: 10.1210/endo-85-3-603.PMID: 5793041 No abstract available.1,876Cite
[The anthelminthic effect of phenylen-diisothicyanate-(1,4) in dogs].
Lämmler G, Saupe E.Z Tropenmed Parasitol. 1969 Sep;20(3):346-50.PMID: 5380278 German. No abstract available.1,877Cite
[Decrease of admixture of chlortetracycline formed during direct fermentation of tetracycline].
Makarevich VG, Laznikova TN.Antibiotiki. 1969 Aug;14(8):695-8.PMID: 5378152 Russian. No abstract available.1,878Cite
Bhandari B, Shrimali LN.J Trop Med Hyg. 1969 Jul;72(7):164-6.PMID: 5795954 No abstract available.1,879Cite
Thyroid proteins in a goitrous cretin with iodide organification defect.
Mouriz J, Riesco G, Usobiaga P.J Clin Endocrinol Metab. 1969 Jul;29(7):942-7. doi: 10.1210/jcem-29-7-942.PMID: 5793453 No abstract available.1,880Cite
Iodide goiter and the pharmacologic effects of excess iodide.
Wolff J.Am J Med. 1969 Jul;47(1):101-24. doi: 10.1016/0002-9343(69)90245-9.PMID: 4307521 Review. No abstract available.1,881Cite
Terpene compounds as drugs. VI. Acyclic mono- and sesquiterpene thiocyanates and isothiocyanates.
Pala G, Mantegani A, Coppi G.J Med Chem. 1969 Jul;12(4):725-6. doi: 10.1021/jm00304a054.PMID: 4307375 No abstract available.1,882Cite
Translocation of some anions cations and acids in rat liver mitochondria.
Mitchell P, Moyle J.Eur J Biochem. 1969 Jun;9(2):149-55. doi: 10.1111/j.1432-1033.1969.tb00588.x.PMID: 5804494 Free article. No abstract available.1,883Cite
Phenylene di-isothiocyanate in the treatment of adult patients infected with hookworm.
Bhandari B, Singh SV.Ann Trop Med Parasitol. 1969 Jun;63(2):177-80. doi: 10.1080/00034983.1969.11686615.PMID: 5372134 No abstract available.1,884Cite
Marie J, Rivière R, Hennequet A, Desbois JC, Seince JM.Ann Pediatr (Paris). 1969 Jun-Jul;16(6):424-36.PMID: 4184994 French. No abstract available.1,885Cite
Maeda H, Ishida N, Kawauchi H, Tsujimura K.J Biochem. 1969 May;65(5):777-83. doi: 10.1093/oxfordjournals.jbchem.a129077.PMID: 5806968 Free article. No abstract available.1,886Cite
Miller JK, Moss BR, Swanson EW.J Dairy Sci. 1969 May;52(5):677-83. doi: 10.3168/jds.S0022-0302(69)86627-0.PMID: 5359620 Free article. No abstract available.1,887Cite
[Antimicrobial effect of potential isothiocyanate-formers. 5].
Zsolnai T.Arzneimittelforschung. 1969 Apr;19(4):558-72.PMID: 4306636 German. No abstract available.1,888Cite
Identification of essential residues in lysozyme: a pulse radiolysis method.
Aldrich JE, Cundall RB, Adams GE, Willson RL.Nature. 1969 Mar 15;221(5185):1049-50. doi: 10.1038/2211049a0.PMID: 5774394 No abstract available.1,889Cite
[No authors listed]Nature. 1969 Mar 8;221(5184):907.PMID: 5765500 No abstract available.1,890Cite
Antistreptococcal activity of lactoperoxidase.
Steele WF, Morrison M.J Bacteriol. 1969 Feb;97(2):635-9. doi: 10.1128/jb.97.2.635-639.1969.PMID: 5773015 Free PMC article.
A study of the inhibition of the growth of Streptococcus cremoris 972 by the enzyme lactoperoxidase has shown, in agreement with previous investigations, that the inhibition requires a source of both peroxide and thiocyanate. The thiocyanate may play more than one r …1,891Cite
[Selective cultivation of coagulase-positive staphylococci from chopped meat].
Sinell HJ, Kusch D.Arch Hyg Bakteriol. 1969 Feb;153(1):56-66.PMID: 4313420 German. No abstract available.1,892Cite
Haynes DH, Kowalsky A, Pressman BC.J Biol Chem. 1969 Jan 25;244(2):502-5.PMID: 5773311 Free article. No abstract available.1,893Cite
Phynelene-diisothiocyanate (1,4) in the treatment of ancylostomiasis in U.A.R.
Saif M, Abdallah A, Abdel-Fattah F, Abdel-Meguid M.J Egypt Med Assoc. 1969;52(10):825-9.PMID: 5383236 No abstract available.1,894Cite
Turbeck BO, Graae J.Acta Chem Scand. 1969;23(7):2414-20. doi: 10.3891/acta.chem.scand.23-2414.PMID: 5368545 No abstract available.1,895Cite
[Structure of KNCS-complexes of nonactin].
Dobler M, Dunitz JD, Kilbourn BT.Helv Chim Acta. 1969;52(8):2573-83. doi: 10.1002/hlca.19690520840.PMID: 5361922 German. No abstract available.1,896Cite
Allyl isothiocyanate: a new broad-spectrum antibiotic from nasturtium.
Pulverer G.Ger Med Mon. 1969 Jan;14(1):27-30.PMID: 5352741 No abstract available.1,897Cite
On the mechanism of the radiation-induced inactivation of lysozyme in dilute aqueous solution.
Adams GE, Willson RL, Aldrich JE, Cundall RB.Int J Radiat Biol Relat Stud Phys Chem Med. 1969;16(4):333-42. doi: 10.1080/09553006914551361.PMID: 5308926 No abstract available.1,898Cite
Profft E, Teubner H, Weuffen W.Arch Exp Veterinarmed. 1969;23(3):587-95.PMID: 4987141 German. No abstract available.1,899Cite
A blood-testis barrier restricting passage from blood into rete testis fluid but not into lymph.
Setchell BP, Voglmayr JK, Waites GM.J Physiol. 1969 Jan;200(1):73-85. doi: 10.1113/jphysiol.1969.sp008682.PMID: 4973530 Free PMC article.1,900Cite
Benjaminson MA.Stain Technol. 1969 Jan;44(1):27-31. doi: 10.3109/10520296909063320.PMID: 4178843 No abstract available.1,901Cite
Fluctuation of thyroid function following a single and repeated administration of antithyroid drugs.
Langer P.Endocrinology. 1968 Dec;83(6):1268-72. doi: 10.1210/endo-83-6-1268.PMID: 4177462 No abstract available.1,902Cite
Deshpande VN.Hindustan Antibiot Bull. 1968 Nov;11(2):106-12.PMID: 5717534 No abstract available.1,903Cite
Removal of fluorescein isothiocyanate from Sephadex after filtration of conjugated proteins.
Reisher JI, Orr HC.Anal Biochem. 1968 Oct 10;26(1):178-9. doi: 10.1016/0003-2697(68)90041-9.PMID: 4990827 No abstract available.1,904Cite
Effect of thiocyanate on iodide concentrating systems of the calf.
Moss BR, Hall RF, Miller JK, Swanson EW.Proc Soc Exp Biol Med. 1968 Oct;129(1):153-5. doi: 10.3181/00379727-129-33272.PMID: 5686500 No abstract available.1,905Cite
Weuffen W, Mentel R.Pharmazie. 1968 Oct;23(10):579-82.PMID: 4887987 German. No abstract available.1,906Cite
[Antimicrobial effect of potential isothiocyanate components. 4].
Zsolnai T.Arzneimittelforschung. 1968 Oct;18(10):1319-24.PMID: 4303565 German. No abstract available.1,907Cite
Dog thyroiditis: occurrence and similarity to Hashimoto’s struma.
Beierwaltes WH, Nishiyama RH.Endocrinology. 1968 Sep;83(3):501-8. doi: 10.1210/endo-83-3-501.PMID: 5695421 No abstract available.1,908Cite
Saji S, Morioka T, Matsumura T.J Osaka Univ Dent Sch. 1968 Sep;8:33-7.PMID: 5250867 No abstract available.1,909Cite
[Antimicrobial effect of potential isothiocyanate producers. 3].
Zsolnai T.Arzneimittelforschung. 1968 Sep;18(9):1169-76.PMID: 4303858 German. No abstract available.1,910Cite
Antibacterial activity of the purified peroxidase from human parotid saliva.
Slowey RR, Eidelman S, Klebanoff SJ.J Bacteriol. 1968 Sep;96(3):575-9. doi: 10.1128/jb.96.3.575-579.1968.PMID: 4183966 Free PMC article.
However, it had an inhibitory effect on the growth of Lactobacillus acidophilus in complete growth medium and on lysine accumulation by L. acidophilus in a buffer-glucose medium, when combined with thiocyanate ions. The concentrations of peroxidase and thiocyanate i …1,911Cite
[Benzyl mustard oil–a broad spectrum antibiotic from the nasturtium].
Pulverer G.Dtsch Med Wochenschr. 1968 Aug 30;93(35):1642 passim. doi: 10.1055/s-0028-1110801.PMID: 5666889 German. No abstract available.1,912Cite
[No authors listed]Nature. 1968 Aug 24;219(5156):816-7. doi: 10.1038/219816a0.PMID: 4876936 No abstract available.1,913Cite
Augustín J, Drobnica L, Nemec P, Antos K, Kristián P, Martvon A, Uher M.J Antibiot (Tokyo). 1968 Aug;21(8):504-8. doi: 10.7164/antibiotics.21.504.PMID: 5715492 Free article. No abstract available.1,914Cite
Augustín J, Drobnica L, Nemec P, Antos K, Kalamár J, Kristián P.J Antibiot (Tokyo). 1968 Aug;21(8):497-503. doi: 10.7164/antibiotics.21.497.PMID: 5715491 Free article. No abstract available.1,915Cite
Drobnica L, Augustín J, Svoboda A, Necas O.Can J Microbiol. 1968 Aug;14(8):853-60. doi: 10.1139/m68-144.PMID: 5667337 No abstract available.1,916Cite
Anticryptoccal serum factors in experimental liver disease.
Gadebusch HH.Z Naturforsch B. 1968 Aug;23(8):1091-5. doi: 10.1515/znb-1968-0815.PMID: 4178891 No abstract available.1,917Cite
Antithyroid activity of some naturally occurring isothiocyanates in vitro.
Langer P, Greer MA.Metabolism. 1968 Jul;17(7):596-605. doi: 10.1016/0026-0495(68)90018-8.PMID: 5656976 No abstract available.1,918Cite
Comparison of chloro and thiocyanato groups as fungal toxiphores in dinitrobenzenes.
Summers LA, Black AL.Naturwissenschaften. 1968 Jun;55(6):299. doi: 10.1007/BF00591717.PMID: 5680108 No abstract available.1,919Cite
Structure-activity correlations for antibacterial agents on gram-positive and gram-negative cells.
Lien EJ, Hansch C, Anderson SM.J Med Chem. 1968 May;11(3):430-41. doi: 10.1021/jm00309a004.PMID: 5656475 No abstract available.1,920Cite
On the increase in rate of heat production caused by stretch in frog’s skeletal muscle.
Clinch NF.J Physiol. 1968 May;196(2):397-414. doi: 10.1113/jphysiol.1968.sp008514.PMID: 5652883 Free PMC article.1,921Cite
[Isotope exploration of the thyroid gland in clinical medicine].
Perez R.Ann Biol Clin (Paris). 1968 May-Jun;26(5):525-66.PMID: 4878747 French. No abstract available.1,922Cite
Transport of methotrexate by the choroid plexus.
Rubin R, Owens E, Rall D.Cancer Res. 1968 Apr;28(4):689-94.PMID: 5649058 No abstract available.1,923Cite
Drobnica L, Zemanová M, Nemec P, Antos K, Kristián P, Martvon A, Závodská E.Appl Microbiol. 1968 Apr;16(4):582-7. doi: 10.1128/am.16.4.582-587.1968.PMID: 5647516 Free PMC article.1,924Cite
Fluorometric determinations comparable to eye response.
Sinsheimer JE, Stewart JT, Burckhalter JH.J Pharm Sci. 1968 Feb;57(2):333-5. doi: 10.1002/jps.2600570224.PMID: 5641686 No abstract available.1,925Cite
Cell-like structures from simple molecules under simulated primitive earth conditions.
Smith AE, Silver JJ, Steinman G.Experientia. 1968 Jan 15;24(1):36-8. doi: 10.1007/BF02136777.PMID: 5637610 No abstract available.1,926Cite
Weuffen W.Arch Exp Veterinarmed. 1968;22(1):127-32.PMID: 5681877 German. No abstract available.1,927Cite
[Contributions to the synthesis of sulphur-containing mustard oils of antimicrobial action].
Vinkler E, Klivényi F, Stájer G, Ferenczy L.Acta Pharm Hung. 1968 Jan;38(1):6-14.PMID: 4973641 Hungarian. No abstract available.1,928Cite
Biosynthesis of tetracycline. Strain improvement and taxonomy of productive streptomyces.
Palecková F, Rehácek Z, Hostálek Z.Folia Microbiol (Praha). 1968;13(5):419-23. doi: 10.1007/BF02869193.PMID: 4880676 No abstract available.1,929Cite
Palleschi M, Palleschi A, D’Amore F.Clin Ter. 1967 Dec 15;43(5):481-90.PMID: 4389842 Review. Italian. No abstract available.1,930Cite
Purification and iodinating activity of hog thyroid peroxidase.
Coval ML, Taurog A.J Biol Chem. 1967 Dec 10;242(23):5510-23.PMID: 12325367 Free article. No abstract available.1,931Cite
Effects of perchlorate and other anions on thyroxine metabolism in the rat.
Yamada T.Endocrinology. 1967 Dec;81(6):1285-90. doi: 10.1210/endo-81-6-1285.PMID: 4169022 No abstract available.1,932Cite
[Enzymological and histological changes in experimental cholestasis].
Seidlová V, Dusek J, Pelikán V, Vaverkova H, Kalab M, Sérova Z.Dtsch Z Verdau Stoffwechselkr. 1967 Nov;27(3):83-94.PMID: 5595734 German. No abstract available.1,933Cite
Theus PM, Weuffen W, Herrmann H.Pharmazie. 1967 Oct;22(10):584-90.PMID: 4971606 German. No abstract available.1,934Cite
Weuffen W, Dorn H.Pharmazie. 1967 Oct;22(10):580-3.PMID: 4971605 German. No abstract available.1,935Cite
Kleine TO.Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1967 Sep 15;258(3):215-28.PMID: 4231008 German. No abstract available.1,936Cite
Rao KV, Rao PL, Praphulla HB, Puttaswamy TL, Ramanathan S.Br J Pharmacol Chemother. 1967 Sep;31(1):11-8. doi: 10.1111/j.1476-5381.1967.tb01971.x.PMID: 6055246 Free PMC article. No abstract available.1,937Cite
Weuffen W, Göckeritz D, Pohloudek-Fabini R.Pharmazie. 1967 Sep;22(9):506-10.PMID: 4971000 German. No abstract available.1,938Cite
Drobnica L, Zemanová M, Nemec P, Kristián P, Antos K, Hulka A.Appl Microbiol. 1967 Jul;15(4):710-7. doi: 10.1128/am.15.4.710-717.1967.PMID: 6049295 Free PMC article.1,939Cite
Drobnica L, Zemanová M, Nemec P, Antos K, Kristián P, Stullerová A, Knoppová V, Nemec P Jr.Appl Microbiol. 1967 Jul;15(4):701-9. doi: 10.1128/am.15.4.701-709.1967.PMID: 6049294 Free PMC article.1,940Cite
Hamada Y, Sugihara H, Ito Y, Ito K, Tomomatsu S.Bull Pharm Res Inst. 1967 Jul;69:7-10.PMID: 5630787 No abstract available.1,941Cite
Effect of thiocyanate on iodine concentrating mechanisms in the calf. ORO-661.
Miller JK, Hall RF, Swanson EW.ORO Rep. 1967 Jul 1:70-2.PMID: 5305480 No abstract available.1,942Cite
Morgan AR, Wells RD, Khorana HG.J Mol Biol. 1967 Jun 28;26(3):477-97. doi: 10.1016/0022-2836(67)90316-6.PMID: 5339796 No abstract available.1,943Cite
Hamada Y, Sugihara H, Ito Y, Ito K, Tomomatsu S.Yakugaku Zasshi. 1967 May;87(5):591-6. doi: 10.1248/yakushi1947.87.5_591.PMID: 5624506 Japanese. No abstract available.1,944Cite
Nonhormonal iodine escape from the normal and abnormal thyroid gland.
Ohtaki S, Moriya S, Suzuki H, Moriuchi Y.J Clin Endocrinol Metab. 1967 May;27(5):728-40. doi: 10.1210/jcem-27-5-728.PMID: 4164901 No abstract available.1,945Cite
Bioelectric phenomena related to protein-fixed charge in a crab nerve fiber.
Lieberman EM, Perkins MS, Tomita T, Wright EB.Science. 1967 Apr 14;156(3772):240-2. doi: 10.1126/science.156.3772.240.PMID: 60210411,946Cite
Super-stoichiometric ratios between ion movements and electron transport in rat liver mitochondria.
Carafoli E, Gamble RL, Rossi CS, Lehninger AL.J Biol Chem. 1967 Mar 25;242(6):1199-204.PMID: 6024755 Free article. No abstract available.1,947Cite
Weuffen W.Arch Exp Veterinarmed. 1967;21(1):235-42.PMID: 5604226 German. No abstract available.1,948Cite
Profft E, Teubner H, Weuffen W.Arch Exp Veterinarmed. 1967;21(1):224-33.PMID: 4973678 German. No abstract available.1,949Cite
Götz HG.Pharm Prax. 1967;9:258-64.PMID: 4183277 Review. German. No abstract available.1,950Cite
[Experimental studies on the solubility and stability of 4,4′-diisoamyloxy-thiocarbanilidde].
Nestler HJ, Seydel J.Arzneimittelforschung. 1966 Nov;16(11):1494-500.PMID: 6014965 German. No abstract available.1,951Cite
Ultracentrifugal behavior of transferrin in the presence of some anions.
Bezkorovainy A.Biochim Biophys Acta. 1966 Oct 10;126(2):286-91. doi: 10.1016/0926-6585(66)90065-3.PMID: 5971854 No abstract available.1,952Cite
Oram JD, Reiter B.Biochem J. 1966 Aug;100(2):382-8. doi: 10.1042/bj1000382.PMID: 5338806 Free PMC article.
The products of the lactoperoxidase-catalysed oxidation of thiocyanate by hydrogen peroxide were sulphate, carbon dioxide and ammonia. Cyanate, sulphite and a compound showing increased extinction at 235mmu (the ;235 compound’) were intermediate oxidation products. 2. …T …1,953Cite
Oram JD, Reiter B.Biochem J. 1966 Aug;100(2):373-81. doi: 10.1042/bj1000373.PMID: 4290983 Free PMC article.
The growth of the lactoperoxidase-sensitive Streptococcus cremoris 972 in a synthetic medium was inhibited by lactoperoxidase and thiocyanate. The glycolysis and oxygen uptake of suspensions of Strep. cremoris 972 in glucose or lactose were also inhibited. The lactoperoxid …1,954Cite
Effects of thiocyanate, perchlorate and other anions on thyroidal iodine metabolism.
Greer MA, Stott AK, Milne KA.Endocrinology. 1966 Aug;79(2):237-47. doi: 10.1210/endo-79-2-237.PMID: 4288428 No abstract available.1,955Cite
[The antimicrobial activity of thiocyanates and isothiocyantes. 1].
Zsolnai T.Arzneimittelforschung. 1966 Jul;16(7):870-6.PMID: 4967663 German. No abstract available.1,956Cite
Oxidation of thiocyanate, another index of thyroid function.
Maloof F, Soodak M.Endocrinology. 1966 Jun;78(6):1198-204. doi: 10.1210/endo-78-6-1198.PMID: 4288354 No abstract available.1,957Cite
Kagawa Y, Racker E.J Biol Chem. 1966 May 25;241(10):2475-82.PMID: 4223642 Free article. No abstract available.1,958Cite
Clem WH, Klebanoff SJ.J Bacteriol. 1966 May;91(5):1848-53. doi: 10.1128/jb.91.5.1848-1853.1966.PMID: 4957025 Free PMC article.
This antimicrobial system consists of the salivary peroxidase (lactoperoxidase) and thiocyanate ions, and requires the presence of H(2)O(2). …Thus, the inhibition of glutamic acid accumulation by saliva appears to be due in part to the lactoperoxidase-thiocyana …1,959Cite
Properties of macrophage receptors for cytophilic antibodies.
Howard JG, Benacerraf B.Br J Exp Pathol. 1966 Apr;47(2):193-200.PMID: 5949693 Free PMC article. No abstract available.1,960Cite
The peroxidase-thiocyanate-hydrogen peroxide antimicrobial system.
Klebanoff SJ, Clem WH, Luebke RG.Biochim Biophys Acta. 1966 Mar 28;117(1):63-72. doi: 10.1016/0304-4165(66)90152-8.PMID: 4380562 No abstract available.1,961Cite
[The structure and fungicidal action of monosubstituted arylisothiocyanates].
Stopkan’ VV, Cherepenko TI, Dubenko GD, Peretiazhko MZ.Mikrobiologiia. 1966 Mar-Apr;35(2):269-70.PMID: 6004938 Russian. No abstract available.1,962Cite
A new ion association technique for demonstrating polyanions in tissue sections.
Zugibe FT, Fink ML.J Histochem Cytochem. 1966 Feb;14(2):147-52. doi: 10.1177/14.2.147.PMID: 5949895 No abstract available.1,963Cite
[On mechanism of strontium deposition in bone tissue].
Berger HJ, Eger W.Acta Histochem. 1965 Dec 24;22(5):298-308.PMID: 4225675 German. No abstract available.1,964Cite
Roberts RJ, Plaa GL.J Pharmacol Exp Ther. 1965 Dec;150(3):499-506.PMID: 5852882 No abstract available.1,965Cite
The thiocyanate suppression test in thyroid disorders.
Friis T, Norregård S.Acta Med Scand. 1965 Oct;178(4):475-81. doi: 10.1111/j.0954-6820.1965.tb04292.x.PMID: 5838319 No abstract available.1,966Cite
“Endemic coast goitre” in Hokkaido, Japan.
Suzuki H, Higuchi T, Sawa K, Ohtaki S, Horiuchi Y.Acta Endocrinol (Copenh). 1965 Oct;50(2):161-76.PMID: 4158495 No abstract available.1,967Cite
[RESEARCH ON THE EFFECT OF THIOCYANATE ON THE IODINE METABOLISM OF THE HUMAN THYROID].
REINWEIN D, IRMSCHER K.Acta Endocrinol (Copenh). 1965 Aug;49:629-40.PMID: 14329836 German. No abstract available.1,968Cite
Effect of feeding thiocyanate to dairy cows on absorption and clearance of intramammary iodine.
Miller JK, Swanson EW, Cragle RG.J Dairy Sci. 1965 Aug;48(8):1118-21. doi: 10.3168/jds.S0022-0302(65)88407-7.PMID: 5837887 Free article. No abstract available.1,969Cite
THE EFFECT OF PROLONGED FEEDING OF GOITROGENS ON THYROID FUNCTION IN RATS.
BROADHEAD GD, PEARSON IB, WILSON GM.J Endocrinol. 1965 Jul;32:341-51. doi: 10.1677/joe.0.0320341.PMID: 14322056 No abstract available.1,970Cite
Bacíková D, Nemec P, Drobnica L, Antos K, Kristián P, Hulka A.J Antibiot (Tokyo). 1965 Jul;18(4):162-70.PMID: 5898329 No abstract available.1,971Cite
BODY FLUIDS AND BLOOD ELECTROLYTES IN DOGS SUBJECTED TO CHRONIC ETHANOL ADMINISTRATION.
BEARD JD, BARLOW G, OVERMAN RR.J Pharmacol Exp Ther. 1965 Jun;148:348-55.PMID: 14334269 No abstract available.1,972Cite
[COBALT-THIOCYANIC COMPLEXES OF SOME PHENOTHIAZINE DERIVATIVES].
MESNARD P, LAGUBEAU J.C R Hebd Seances Acad Sci. 1965 Apr 5;260:3993-4.PMID: 14341949 French. No abstract available.1,973Cite
STUDIES ON AN IODINATING ENZYME FROM CALF THYROID.
DEGROOT LJ, THOMPSON JE, DUNN AD.Endocrinology. 1965 Apr;76:632-45. doi: 10.1210/endo-76-4-632.PMID: 14289184 No abstract available.1,974Cite
SYNERGISTIC INHIBITION OF XANTHINE OXIDASE BY GUANIDINIUM PLUS THIOCYANATE.
FRIDOVICH I.Arch Biochem Biophys. 1965 Mar;109:511-5. doi: 10.1016/0003-9861(65)90395-4.PMID: 14320492 No abstract available.1,975Cite
PHOTOCHEMICAL SYNTHESIS OF AMINO ACIDS.
KOLOMIYCHENKO MA.Fed Proc Transl Suppl. 1965 Mar-Apr;24:199-202.PMID: 14304745 No abstract available.1,976Cite
SEASONAL CHANGES IN IODINE METABOLISM. 1. IODINE CONTENT OF COWS’ MILK.
BROADHEAD GD, PEARSON IB, WILSON GM.Br Med J. 1965 Feb 6;1(5431):343-8. doi: 10.1136/bmj.1.5431.343.PMID: 14237899 Free PMC article. No abstract available.1,977Cite
WOJTCZAK L, ZALUSKA H, DRAHOTA Z.Biochim Biophys Acta. 1965 Feb 1;98:8-18. doi: 10.1016/0005-2760(65)90003-2.PMID: 14290843 No abstract available.1,978Cite
GOITROGENIC ACTIVITY OF ALLYLISOTHIOCYANATE–A WIDESPREAD NATURAL MUSTARD OIL.
LANGER P, STOLC V.Endocrinology. 1965 Jan;76:151-5. doi: 10.1210/endo-76-1-151.PMID: 14254190 No abstract available.1,979Cite
[Autoradiographic studies on the influence of thiocyanate on iodine metabolism].
Kutzim H.Nucl Med (Stuttg). 1965:Suppl 2:201+.PMID: 5888821 German. No abstract available.1,980Cite
FOLLIS RH Jr.Lab Invest. 1964 Dec;13:1590-9.PMID: 14246669 No abstract available.1,981Cite
[METABOLISM OF INTRATHYROIDAL IODINE].
SHIZUME K, NAGATAKI S.Nihon Naibunpi Gakkai Zasshi. 1964 Nov 20;40:1082-7.PMID: 14253317 Japanese. No abstract available.1,982Cite
BOSLY J.J Pharm Belg. 1964 Nov-Dec;19:513-24.PMID: 14266540 French. No abstract available.1,983Cite
[STUDIES ON METHODS OF STANDARDIZATION OF O.1 N SILVER NITRATE AND O.1 N AMMONIUM THIOCYANATE].
SHBAZAKI T, WADA Y.Eisei Shikenjo Hokoku. 1964 Oct;82:78-9.PMID: 14343195 Japanese. No abstract available.1,984Cite
[TREATMENT OF HYPERTHYROIDISM].
REGNIERS P, VAN RAEPENBUSCH, VERMEULEN A.Belg Tijdschr Geneesk. 1964 Oct 1;20:1012-22.PMID: 14240630 Dutch. No abstract available.1,985Cite
RAMADANM EL-D, ELASMAR F, GREENBERG DM.Arch Biochem Biophys. 1964 Oct;108:150-7. doi: 10.1016/0003-9861(64)90366-2.PMID: 14233907 No abstract available.1,986Cite
POHLOUDEK-FABINI R, WEUFFEN W.Mitt Dtsch Pharm Ges Pharm Ges DDR. 1964 Sep;34:554-65.PMID: 14343957 German. No abstract available.1,987Cite
POHLOUDEK-FABINI R, WEUFFEN E.Arch Pharm Ber Dtsch Pharm Ges. 1964 Sep;297:554-65. doi: 10.1002/ardp.19642970908.PMID: 14341920 German. No abstract available.1,988Cite
TOMPSETT SL.Clin Chim Acta. 1964 Jul;10:81-9. doi: 10.1016/0009-8981(64)90219-0.PMID: 14216194 No abstract available.1,989Cite
A DISSIMILATORY NITRATE REDUCTASE FROM NEUROSPORA CRASSA.
NICHOLAS DJ, WILSON PJ.Biochim Biophys Acta. 1964 Jun 8;86:466-76. doi: 10.1016/0304-4165(64)90086-8.PMID: 14192898 No abstract available.1,990Cite
[ANTITUBERCULAR ALKYLMERCAPTOETHYLUREAS AND THIOSEMICARBAZIDES].
BABUDIERI B, PORCELLI GA, STEIN ML, ZARDI O.Farmaco Sci. 1964 Jun;19:537-42.PMID: 14174307 Italian. No abstract available.1,991Cite
EVIDENCE FOR A THYROID-INHIBITING FACTOR OF ADENOHYPOPHYSIAL ORIGIN.
POSNER I, PIMENTEL E.Am J Physiol. 1964 May;206:1145-50. doi: 10.1152/ajplegacy.1964.206.5.1145.PMID: 14208956 No abstract available.1,992Cite
WEUFFEN W, POHLOUDEK-FABINI R.Pharmazie. 1964 Apr;19:249-61.PMID: 14240178 Review. German. No abstract available.1,993Cite
KINUGAWA J, OCHIAI M, MATSUMURA C, YAMAMOTO H.Chem Pharm Bull (Tokyo). 1964 Apr;12:433-40. doi: 10.1248/cpb.12.433.PMID: 14187039 No abstract available.1,994Cite
HOSTALEK Z.Folia Microbiol (Praha). 1964 Mar;18:96-102. doi: 10.1007/BF02868790.PMID: 14149849 No abstract available.1,995Cite
HOSTALEK Z.Folia Microbiol (Praha). 1964 Mar;18:89-95. doi: 10.1007/BF02868789.PMID: 14149848 No abstract available.1,996Cite
HOSTALEK Z.Folia Microbiol (Praha). 1964 Mar;18:78-88. doi: 10.1007/BF02868788.PMID: 14149847 No abstract available.1,997Cite
WIBERG GS, CARTER JR, STEPHENSON NR.Acta Endocrinol (Copenh). 1964 Mar;45:370-80. doi: 10.1530/acta.0.0450370.PMID: 14131769 No abstract available.1,998Cite
CHANGES IN THE HAEMOLYTIC ACTIVITY OF SENDAI VIRUS AFTER DIFFERENT CHEMICAL AND PHYSICAL TREATMENTS.
NEURATH AR.Acta Virol. 1964 Mar;8:143-53.PMID: 14127273 No abstract available.1,999Cite
ROCHE J, ANDRE S, COVELLI I.Comp Biochem Physiol. 1964 Feb;11:215-21. doi: 10.1016/0010-406x(64)90164-1.PMID: 14158591 French. No abstract available.2,000Cite
POTENTIATION OF MUSCULAR CONTRACTION.
SANDOW A.Arch Phys Med Rehabil. 1964 Feb;45:62-81.PMID: 14130054 Review. No abstract available.
PLACENTAL TRANSFER OF 131-I-LABELLED IODIDE IN THE GUINEA-PIG.
LONDON WT, MONEY WL, RAWSON RW.J Endocrinol. 1964 Feb;28:247-52. doi: 10.1677/joe.0.0280247.PMID: 14123865 No abstract available.2,002Cite
STUDIES ON FUNGICIDES. VI. SYNTHESIS OF THIOCYANATOPYRAZOLES.
KINUGAWA J, OCHIAI M.Chem Pharm Bull (Tokyo). 1964 Jan;12:23-33. doi: 10.1248/cpb.12.23.PMID: 14185749 No abstract available.2,003Cite
LANGER P, STOLE V.Hoppe Seylers Z Physiol Chem. 1964;335:216-20. doi: 10.1515/bchm2.1964.335.1.216.PMID: 14124984 German. No abstract available.2,004Cite
SAVOIE JC, JUNGERS P.Ann Endocrinol (Paris). 1963 Nov-Dec;24:975-84.PMID: 14098092 French. No abstract available.2,005Cite
KINUGAWA J, OCHIAI M, YAMAMOTO H.Yakugaku Zasshi. 1963 Nov;83:1086-91.PMID: 14084798 Japanese. No abstract available.2,006Cite
ROCHE J, ANDRE S, COVELLI I.Comp Biochem Physiol. 1963 Aug;9:291-300. doi: 10.1016/0010-406x(63)90003-3.PMID: 14109724 French. No abstract available.2,007Cite
[STUDIES ON FUNGICIDES. IV. SYNTHESIS AND ANTIFUNGAL ACTIVITY OF THIOCYANATOPYRIDAZINE DERIVATIVES].
KINUGAWA J, OCHIAI M, YAMAMOTO H.Yakugaku Zasshi. 1963 Aug;83:767-71.PMID: 14087705 Japanese. No abstract available.2,008Cite
RIECHE A, HILGETAG G, MARTIN D, KREYZI I.Arch Pharm Ber Dtsch Pharm Ges. 1963 May;296:310-24. doi: 10.1002/ardp.19632960508.PMID: 13982249 German. No abstract available.2,009Cite
The passage of certain substances out of the cerebrosphinal fluid.
POLLAY M, DAVSON H.Brain. 1963 Mar;86:137-50. doi: 10.1093/brain/86.1.137.PMID: 13972012 No abstract available.2,010Cite
THE EFFECT OF THIOCYANATE IN NUTRITION ON THE IODINE CONTENT OF COW’S MILK.
PIIRONEN E, VIRTANEN AI.Z Ernahrungswiss. 1963 Feb;3:140-7. doi: 10.1007/BF02018672.PMID: 14153233 No abstract available.2,011Cite
[On halogen and “pseudohalogen” compounds of 18-desoxymethylreserpinate].
POPELAK A, LETTENBAUER G, HAACK E.Arch Pharm Ber Dtsch Pharm Ges. 1963 Feb;296/68:67-72. doi: 10.1002/ardp.19632960203.PMID: 13972198 German. No abstract available.2,012Cite
ZELDOW BJ.J Immunol. 1963 Jan;90:12-6.PMID: 14003407 No abstract available.2,013Cite
Nematocide residues in plants.
TAYLOR AL.Residue Rev. 1963;2:1-8. doi: 10.1007/978-1-4615-8374-5_1.PMID: 13993544 No abstract available.2,014Cite
Inhibition by thiocyanate of accumulation of radioiodine by thyroid gland.
WOLLMAN SH.Am J Physiol. 1962 Sep;203:517-24. doi: 10.1152/ajplegacy.1962.203.3.517.PMID: 14008093 No abstract available.2,015Cite
Chemical, chromatographic and radioisotopic techniques in an experimental study of thyroid function.
HATHAWAY DS, LIPSCOMB HS.Tex Rep Biol Med. 1962;20:204-13.PMID: 13905340 No abstract available.2,016Cite
LANGER P.Hoppe Seylers Z Physiol Chem. 1961 May 3;323:194-8. doi: 10.1515/bchm2.1961.323.1.194.PMID: 13758850 German. No abstract available.2,017Cite
The reaction of beta-lactoglobulin sulfenyl iodide with mercaptans, thiouracil and thiocyanate.
CUNNINGHAM LW, NUENKE BJ.Biochim Biophys Acta. 1960 Apr 22;39:565-6. doi: 10.1016/0006-3002(60)90222-5.PMID: 13813315 No abstract available.2,018Cite
POHLOUDEK-FABINI R, WEUFFEN W.Arch Pharm Ber Dtsch Pharm Ges. 1960 Mar;293/65:333-42. doi: 10.1002/ardp.19602930312.PMID: 14433668 German. No abstract available.2,019Cite
[On the antibacterial effect of a thiocyanate compound in vitro].
RITZERFELD W.Arzneimittelforschung. 1960 Jan;10:48-9.PMID: 14437634 German. No abstract available.2,020Cite
CHMEL L, BUCHVALD J, DROBNICA L.Cesk Dermatol. 1959 Dec;34:365-73.PMID: 13693200 Czech. No abstract available.2,021Cite
HEROLD M, HOSTALEK Z, NECASEK J, MATELOVA V.Antibiotiki. 1959 Sep-Oct;4:33-5.PMID: 14401316 Russian. No abstract available.2,022Cite
[Thiocyanate test in the elevated and level curves of thyroid fixation of I-131].
MILLER G, ROUX H, VAGUE J.Ann Endocrinol (Paris). 1959 Jul-Aug;20:524-8.PMID: 14422502 French. No abstract available.2,023Cite
MILLER G.Pathol Biol. 1959 Jun;7:1343-7.PMID: 14422504 French. No abstract available.2,024Cite
ORTEL S, WEUFFEN W.Pharmazie. 1959 Apr;14(4):204-14.PMID: 13674886 German. No abstract available.2,025Cite
Depression of iodide uptake of the thyroid by thiocyanate through blocking of the energy supply.
KANAYA R.Endocrinol Jpn. 1959 Mar;6(1):1-8. doi: 10.1507/endocrj1954.6.1.PMID: 13676973 Free article. No abstract available.2,026Cite
HOSTALEK Z, JANECEK J, DOSKOCIL J, KASPAROVA J.Antibiotiki (Mosc). 1959 Jan-Feb;4(1):37-9.PMID: 24545222 Russian. No abstract available.2,027Cite
HOWORKA K.Pharm Zentralhalle Dtschl. 1958 Aug;97(8):374-7.PMID: 13590913 German. No abstract available.2,028Cite
BRUCHMANN I.Tuberkulosearzt. 1958 Mar;12(3):156-61.PMID: 13556990 German. No abstract available.2,029Cite
[Mechanism of action of a tuberculostatic chemotherapeutic agent].
WILDE W.Tuberkulosearzt. 1958 Mar;12(3):154-6.PMID: 13556989 German. No abstract available.2,030Cite
[Variability of microorganisms induced by some antibiotics and chemotherapeutic substances].
OERIU S.Mikrobiologiia. 1958 Mar-Apr;27(2):253-60.PMID: 13551958 Russian. No abstract available.2,031Cite
Stimulation of chlortetracycline production by benzyl thiocyanate.
PECAK V, CIZEK S, MUSIL J, CERKES L, HEROLD M, BELIK E, HOFFMAN J.J Hyg Epidemiol Microbiol Immunol. 1958;2(1):111-5.PMID: 13598900 No abstract available.2,032Cite
[Further research on azorhodanid (dairin)].
SCHMIEDEL A, BARTMANN K.Beitr Klin Tuberk Spezif Tuberkuloseforsch. 1958;118(6):421-34. doi: 10.1007/BF02150213.PMID: 13596292 German. No abstract available.2,033Cite
Antibiotic principle from Moringa pterygosperma. IX. Inhibition of transaminase by isothiocyanates.
DAS BR, NARASIMHA RAO PL.Indian J Med Res. 1958 Jan;46(1):75-7.PMID: 13501879 No abstract available.2,034Cite
[New therapeutic method for chronic otitis media].
SZUCS L.Fulorrgegegyogyaszat. 1957 Oct;(3):126-31.PMID: 13512544 Hungarian. No abstract available.2,035Cite
[Pharmacology and biochemistry of 2,4-diaminoazobenzene monorhodanide].
DENGLER H, BECK E.Arzneimittelforschung. 1957 Sep;7(9):553-8.PMID: 13471400 German. No abstract available.2,036Cite
[Anemia as a side-effect of azorrhodan (dairin) therapy in tuberculosis].
DENGLER H, MESSMER E.Beitr Klin Tuberk Spezif Tuberkuloseforsch. 1957;117(5):537-8.PMID: 13522563 German. No abstract available.2,037Cite
[Possible disinfecting effect of azorhodanid (dairin) on mycobacteria tuberculosis].
BARTMANN K, SCHMIEDEL A.Beitr Klin Tuberk Spezif Tuberkuloseforsch. 1957;117(2):286-95.PMID: 13522544 German, Italian. No abstract available.2,038Cite
VLIJM L.Acta Endocrinol (Copenh). 1956 Jul;22(3):273-8. doi: 10.1530/acta.0.0220273.PMID: 13339065 No abstract available.2,039Cite
Studies on the concentration of radioiodide and thiocyanate by slices of the salivary gland.
FLETCHER K, HONOUR AJ, ROWLANDS EN.Biochem J. 1956 Jun;63(2):194-9. doi: 10.1042/bj0630194.PMID: 13328810 Free PMC article. No abstract available.2,040Cite
GILBERT-DREYFUS, SAVOIE JC, GALI P.Ann Endocrinol (Paris). 1956 May;17(1):83-7.PMID: 13340301 French. No abstract available.2,041Cite
Fibrolysin injections in therapy of corneal scars.
NUYKEN G.Med Klin. 1956 Jan 27;51(4):146-8.PMID: 13296814 English, German. No abstract available.2,042Cite
Effect of potassium thiocyanate on fetal retention of radioiodine.
RUGH R, CLUGSTON H.Endocrinology. 1956 Jan;58(1):8-12. doi: 10.1210/endo-58-1-8.PMID: 13285441 No abstract available.2,043Cite
OERIU I.Stud Cercet Inframicrobiol. 1955 Jul-Dec;6(3-4):577-85.PMID: 13324600 Romanian. No abstract available.2,044Cite
VASILESCU C, STROESCU G, MIRZA E, POPA-NEREANTIU F, CARP N.Bul Stiint Sect Stiint Medicale Acad Republicii Pop Romane. 1955 Jul-Sep;7(3):901-31.PMID: 13293448 Romanian. No abstract available.2,045Cite
The iodide trapping and binding functions of the thyroid.
BERSON SA, YALOW RS.J Clin Invest. 1955 Feb;34(2):186-204. doi: 10.1172/JCI103072.PMID: 13233341 Free PMC article. No abstract available.2,046Cite
SOIMU I, IONESCU C.Stud Cercet Inframicrobiol. 1955 Jan-Jun;6(1-2):277-83.PMID: 13281746 Romanian. No abstract available.2,047Cite
[Study of the components of saliva. II. Possible antibacterial action of thiocyanates].
NIEDDU G.Minerva Stomatol. 1954 Sep-Oct;3(5):185-7.PMID: 14356016 Italian. No abstract available.2,048Cite
SIJPESTEYN AK, VAN DER KERK GJ.Biochim Biophys Acta. 1954 Apr;13(4):545-52. doi: 10.1016/0006-3002(54)90372-8.PMID: 13159993 No abstract available.2,049Cite
KUUSISTO AN, TELKKA A.Ann Med Exp Biol Fenn. 1954;32(4):337-41.PMID: 14377035 No abstract available.2,050Cite
KOSZEGI D, SALGO E.Pharm Zentralhalle Dtschl. 1953 May;92(5):157-60.PMID: 13100009 Undetermined Language. No abstract available.2,051Cite
WYNGAARDEN JB, STANBURY JB, RAPP B.Endocrinology. 1953 May;52(5):568-74. doi: 10.1210/endo-52-5-568.PMID: 13060263 No abstract available.2,052Cite
Antifungal activity of a series of thiocyanates.
LANDIS L, KLEY D, ERCOLI N.J Am Pharm Assoc Am Pharm Assoc. 1951 Jul;40(7):321-5. doi: 10.1002/jps.3030400706.PMID: 14850355 No abstract available.2,053Cite
[Combined hexamine-rhodane therapy of diseases of the urinary tract].
GRUNDMANN I.Med Monatsschr. 1951 Jun;5(6):416-9.PMID: 14862887 Undetermined Language. No abstract available.2,054Cite
The thiocyanate space and iodide space in the thyroid gland.
McCLENDON JF, FOSTER WC, REED E.Biochem J. 1950 Jun-Jul;47(1):53-5. doi: 10.1042/bj0470053.PMID: 14791304 Free PMC article. No abstract available.2,055Cite
WILLHEIM R, HARRISON BL, WILLHEIM O.Exp Med Surg. 1950 May-Nov;8(2-4):426-30.PMID: 15427669 No abstract available.2,056Cite
Mode of action of antithyroid compounds.
PITT-RIVERS R.Physiol Rev. 1950 Apr;30(2):194-5. doi: 10.1152/physrev.1950.30.2.194.PMID: 15424033 No abstract available.2,057Cite
WILLIAMS RH, JAFFE H, TAYLOR JA.Am J Med Sci. 1950 Jan;219(1):7-15. doi: 10.1097/00000441-195001000-00002.PMID: 15402298 No abstract available.2,058Cite
VANREMOORTERE E.Arch Int Pharmacodyn Ther. 1950;84(1):48-56.PMID: 14783444 No abstract available.2,059Cite
RABEN MS.Endocrinology. 1949 Sep;45(3):296-304. doi: 10.1210/endo-45-3-296.PMID: 18140410 No abstract available.2,060Cite
URI N.Analyst. 1947 Nov;72(860):478-81. doi: 10.1039/an9477200478.PMID: 18917685 No abstract available.2,061Cite
The composition of streptomycin Reineckate.
FRIED J, WINTERSTEINER O.Science. 1946 Sep 20;104(2699):273.PMID: 20997612 No abstract available.2,062Cite
VANDERLAAN WP, BISSELL A.Endocrinology. 1946 Aug;39:157-60. doi: 10.1210/endo-39-2-157.PMID: 20996892 No abstract available.2,063Cite
WOLFF J, CHAIKOFF IL, et al.Endocrinology. 1946 Aug;39:140-8. doi: 10.1210/endo-39-2-140.PMID: 20996889 No abstract available.2,064Cite
MONTGOMERY EM, RICHTMYER NK, HUDSON CS.J Org Chem. 1946 May;11:301-6. doi: 10.1021/jo01173a015.PMID: 20983308 No abstract available.
Leave a Reply