Fetal alcohol spectrum disorders (FASD) is a classification of diseases that all result from alcohol exposure during pregnancy. Symptoms of these disorders include poor cerebellar-dependent learning, motor coordination and impaired balance. In rats with FASD, it was shown that they had decreased concentrations of CBP and lower amounts of H3 and H4 acetylation.

• Valor LM, Viosca J, Lopez-Atalaya JP, Barco A (2013-07-31). “Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders”. Current Pharmaceutical Design. 19 (28): 5051–5064. doi:10.2174/13816128113199990382. PMC 3722569. PMID 23448461.