Category: Hormones

  • Digestive enzymes

    Digestive enzymes

    Digestive enzymes are a group of enzymes that break down polymeric macromolecules into their smaller building blocks, in order to facilitate their absorption into the cells of the body. Digestive enzymes are found in the digestive tracts of animals (including humans) and in the tracts of carnivorous plants, where they aid in the digestion of food, as well as inside cells,…

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  • Hapten

    In immunology, haptens are small molecules that elicit an immune response only when attached to a large carrier such as a protein; the carrier may be one that also does not elicit an immune response by itself (in general, only large molecules, infectious agents, or insoluble foreign matter can elicit an immune response in the body). Once the body has generated antibodies to a hapten-carrier adduct, the small-molecule hapten may…

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  • Tetragastrin  is commonly used in scientific research to induce panic attacks 

    Tetragastrin is commonly used in scientific research to induce panic attacks 

    CCK-4 reliably causes severe anxiety symptoms when administered to humans in a dose of as little as 50μg

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  • A tetrapeptide is a peptide, classified as an oligopeptide, since it only consists of four amino acids

    A tetrapeptide is a peptide, classified as an oligopeptide, since it only consists of four amino acids

    Examples of tetrapeptides are: See also Hormones Categories:  From Wikipedia where this page was last updated July 2, 2022

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  • Calcitriol

    Calcitriol

    Medical use Adverse effects Mechanism of action Calcitriol increases blood calcium levels ([Ca2+]) by: Biosynthesis and its regulation Interactive pathway map Metabolism History Names External links Hormones Vitamins (A11) Drugs used for psoriasis (D05) Vitamin D receptor modulators Portal:  Medicine Categories:  From Wikipedia where this page was last updated August 4, 2022

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  • Brain natriuretic peptide 32 (BNP)

    Brain natriuretic peptide 32 (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume. BNP is one of two natriuretic peptides  “UniProt”. www.uniprot.org. Retrieved 11 August 2022. The 32-amino acid polypeptide BNP is secreted attached to a 76–amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. Once released, BNP binds…

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  • Somatostatin

    Not to be confused with Somatocrinin or Somatomedin. Somatostatin, also known as growth hormone-inhibiting hormone (GHIH) or by several other names, is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin inhibits insulin and glucagon secretion.  “somatostatin”. Encyclopædia Britannica. Encyclopædia Britannica Online. Encyclopædia Britannica Inc., 2016. Web. 04 mag. 2016…

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  • All The Hormones

    All The Hormones

    I am posting all the hormones (or a large number of them) for further reference. This is a serious pain the ass but I think it will be worth it. As ever I am starting with the Wikipedia pages and references. The tags will be crazy until I’m finished and maybe much longer. Eventually I…

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  • Triiodothyronine, aka T3

    Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. Bowen, R. (2010-07-24). “Physiologic Effects of Thyroid Hormones”. Colorado State University. Retrieved 2013-09-29. Production of T3 and its prohormone thyroxine (T4) is activated by thyroid-stimulating hormone (TSH), which is released from the anterior pituitary gland. This pathway is part of a closed-loop feedback process: Elevated…

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  • Calcitonin

    Calcitonin

    Calcitonin is a 32 amino acid peptide hormone secreted by PARAFOLLICULAR CELLS (also known as C cells) of the thyroid (or endostyle) in humans and other chordates in the ultimopharyngeal body. It acts to reduce blood calcium (Ca2+), opposing the effects of PARATHYROID HORMONE (PTH). Its importance in humans has not been as well established as its importance in other animals, as its function is usually not significant in the…

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  • Corticotropin-like intermediate [lobe] peptide (CLIP)

    Corticotropin-like intermediate [lobe] peptide (CLIP), also known as adrenocorticotropic hormone fragment 18-39 (ACTH(18-39)), is a naturally occurring, endogenous neuropeptide with a docosapeptide structure and the amino acid sequence  Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe. CLIP is generated as a proteolyic cleavage product of adrenocorticotropic hormone (ACTH), Gianoulakis C, Seidah NG, Routhier R, Chrétien M (December 1979). “Biosynthesis and characterization of adrenocorticotropic hormone, alpha-melanocyte-stimulating hormone, and an NH2-terminal fragment of the adrenocorticotropic hormone/beta-lipotropin precursor from rat pars intermedia”. The…

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  • Melanin-concentrating hormone (MCH) aka PMCH

    Melanin-concentrating hormone (MCH), also known as pro-melanin stimulating hormone (PMCH), is a cyclic 19-amino acid orexigenic hypothalamicpeptide originally isolated from the pituitary gland of teleost fish, where it controls skin pigmentation. Barson JR, Morganstern I, Leibowitz SF (2013). “Complementary roles of orexin and melanin-concentrating hormone in feeding behavior”. International Journal of Endocrinology. 2013: 983964. doi:10.1155/2013/983964. PMC 3727095. PMID 23935621. In mammals it is involved in the regulation of feeding behavior, mood,…

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  • Pro-opiomelanocortin (POMC)

    Pro-opiomelanocortin (POMC) is a precursor polypeptide with 241 amino acid residues. POMC is synthesized in corticotrophs of the anterior pituitary from the 267-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin (pre-POMC), by the removal of a 26-amino-acid-long signal peptide sequence during translation.  “pro-opiomelanocortin preproprotein [Homo sapiens] – Protein – NCBI”. www.ncbi.nlm.nih.gov. Retrieved 30 December 2020. POMC is part of the central melanocortin system. Function POMC is cut (cleaved) to give rise to multiple peptide hormones. Each of these peptides is packaged…

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  • Oxytocin

    Oxytocin (Oxt or OT) is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary.  Gray’s Anatomy: The Anatomical Basis of Clinical Practice (41 ed.). Elsevier Health Sciences. 2015. p. 358. ISBN 978-0-7020-6851-5.  It plays a role in social bonding, reproduction, childbirth, and the period after childbirth. Audunsdottir K, Quintana DS (2022-01-25). “Oxytocin’s dynamic role across the lifespan”. Aging Brain: 100028. doi:10.1016/j.nbas.2021.100028. ISSN 2589-9589. S2CID 246314607. Leng G, Leng RI (November 2021). “Oxytocin: A…

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  • Cholecystokinin aka pancreozymin notes

    History Structure Function Gastrointestinal Digestion Satiety The effects of CCK vary between individuals. For example, in rats , CCK administration significantly reduces hunger in adult males, but is slightly less effective in younger subjects, and even slightly less effective in females. The hunger-suppressive effects of CCK also are reduced in obese rats.  Fink H, Rex A, Voits M, Voigt…

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