Category: Hormones
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Ghrelin or lenomorelin
History and name Gene, transcription products, and structure Ghrelin cells Alternative names Location Features Function and mechanism of action Blood levels Ghrelin receptor Locations of action Glucose metabolism Sleep Reproductive system Fetus and neonate Anorexia and obesity Disease management Gastric bypass surgery See also External links Look up ghrelin in Wiktionary, the free dictionary. Hormones Peptides: neuropeptides Appetite…
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Prolactin receptor modulators
Prolactin Agonists An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the agonist, while an inverse agonist causes an action opposite to that of the agonist. Etymology: From the Greek αγωνιστής (agōnistēs), contestant; champion; rival < αγων (agōn), contest, combat; exertion, struggle…
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Prolactin (PRL)
In mammals, prolactin is associated with milk production; in fish it is thought to be related to the control of water and salt balance. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. It has important cell cycle-related functions as a growth-, differentiating- and anti-apoptotic factor. As a growth factor,…
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Progastrin
Progastrin is an 80-amino acid intracellular protein and the precursor of gastrin, a gastrointestinal hormone produced by G cells in the gastric antrum. Fiona M., Gribble; Frank, Reimann; Geoffrey, P. Roberts (2018). Gastrointestinal Hormones. Physiology of the Gastrointestinal Tract, Elsevier. pp. 31–70. The main function of gastrin is to regulate acid secretion. Rehfeld, Jens F.; Goetze, Jens Peter (2005). “2 The Post-Translational Phase of Gene Expression in Tumor…
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Gastrin
Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas. Gastrin binds to cholecystokinin B receptors to stimulate the release of histamines in enterochromaffin-like cells, and it induces the insertion of K+/H+ ATPase pumps into the apical membrane of parietal cells (which…
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Leydig cells aka interstitial cells of the testes and interstitial cells of Leydig
Leydig cells, also known as interstitial cells of the testes and interstitial cells of Leydig, are found adjacent to the seminiferous tubules in the testicle and produce testosterone in the presence of luteinizing hormone (LH).[1][2] They are polyhedral in shape and have a large, prominent nucleus, an eosinophiliccytoplasm, and numerous lipid-filled vesicles.[3] Structure The mammalian Leydig cell is a polyhedral epithelioid cell with a single eccentrically located ovoid nucleus.…
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Human placental lactogen (hPL)
Human placental lactogen (hPL), also called human chorionic somatomammotropin (HCS), is a polypeptideplacental hormone, the human form of placental lactogen (chorionic somatomammotropin). Its structure and function are similar to those of human growth hormone. It modifies the metabolic state of the mother during pregnancy to facilitate the energy supply of the fetus. hPL has anti-insulin properties. hPL is a hormone secreted by the syncytiotrophoblast during pregnancy. Like human growth hormone, hPL…
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Human chorionic gonadotropin (hCG)
Human chorionic gonadotropin (hCG) is a hormone for the maternal recognition of pregnancy produced by trophoblast cells that are surrounding a growing embryo (syncytiotrophoblast initially), which eventually forms the placenta after implantation. Cole LA (2009). “New discoveries on the biology and detection of human chorionic gonadotropin”. Reprod. Biol. Endocrinol. 7: 8. doi:10.1186/1477-7827-7-8. PMC 2649930. PMID 19171054. Gregory JJ, Finlay JL (April 1999). “Alpha-fetoprotein and beta-human chorionic gonadotropin: their clinical significance as…
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Prostaglandins (PG)
The prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids “Eicosanoid Synthesis and Metabolism: Prostaglandins, Thromboxanes, Leukotrienes, Lipoxins”. themedicalbiochemistrypage.org. Retrieved 2018-09-21. having diverse hormone-like effects in animals. Prostaglandins have been found in almost every tissue in humans and other animals. They are derived enzymatically from the fatty acid arachidonic acid. Ricciotti E, FitzGerald GA (May 2011). “Prostaglandins and inflammation”. Arteriosclerosis, Thrombosis, and Vascular Biology. 31 (5): 986–1000. doi:10.1161/ATVBAHA.110.207449. PMC 3081099. PMID 21508345. Every prostaglandin contains 20 carbon atoms, including…
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Parathyroid hormone (PTH)
Structure Function Regulation of serum calcium Main article: Calcium metabolism Regulation of serum phosphate Vitamin D synthesis Interactive pathway map Click on genes, proteins and metabolites below to link to respective articles. [§ 1] Regulation of PTH secretion Stimulators Inhibitors Disorders Measurement Interpretive guide Condition Intact PTH Calcium Normal Parathyroid Normal Normal Hypoparathyroidism Low or Low Normal [note…
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24S-Hydroxycholesterol
24S-Hydroxycholesterol (24S-HC), also known as cholest-5-ene-3,24-diol or cerebrosterol, is an endogenousoxysterol produced by neurons in the brain to maintain cholesterolhomeostasis. [1] It was discovered in 1953 by Alberto Ercoli, S. Di Frisco, and Pietro de Ruggieri, who first isolated the molecule in the horse brain [2] and then demonstrated its presence in the human brain. [3] 24S-HC is produced by a hydroxy group substitution at carbon number 24 in cholesterol, catalyzed by…
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21-Hydroxypregnenolon
21-Hydroxypregnenolone, also known as prebediolone, as well as 3β,21-dihydroxypregn-5-en-20-one, is a naturally occurring and endogenous pregnane steroid, and an intermediate in the biosynthesis of 11-deoxycorticosterone (21-hydroxyprogesterone), corticosterone (11β,21-dihydroxyprogesterone), and other corticosteroids. [Wishart, David S.; Guo, An Chi; Oler, Eponine; Wang, Fel; Anjum, Afia; Peters, Harrison; Dizon, Raynard; Sayeeda, Zinat; Tian, Siyang; Lee, Brian L.; Berjanskii, Mark; Mah, Robert; Yamamoto, Mai; Jovel Castillo, Juan; Torres Calzada, Claudia; Hiebert Giesbrecht, Mickel; Lui, Vicki…
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17α-Hydroxypregnenolone
17α-Hydroxypregnenolone is a pregnane (C21) steroid that is obtained by hydroxylation of pregnenolone at the C17α position. This step is performed by the mitochondrialcytochrome P450 enzyme 17α-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. Hill M, Lukác D, Lapcík O, Sulcová J, Hampl R, Pouzar V, Stárka L (April 1999). “Age relationships and sex differences…
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Dihydrotestosterone glucuronide
No page at wikipedia – found in a chart
