Neuroscience
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ADAM23: The Neural Navigator
ADAM23 is the protein that’s making waves in the world of neuroscience. ADAM23 is like that friend who’s always helping you find your way around a new city. This protein… Read more.
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Insall R. Dispatch. Dictyostelium chemotaxis: fascism through the back door? Curr Biol. 2003 Apr 29;13(9):R353-4. doi: 10.1016/s0960-9822(03)00274-4. PMID: 12725750.
Abstract Aggregating Dictyostelium cells secrete cyclic AMP to attract their neighbours by chemotaxis. It has now been shown that adenylyl cyclase is enriched in the rear of cells, and this localisation is… Read more.
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Sex-determining region Y protein聽(SRY), or聽testis-determining factor聽(TDF)
Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that is responsible for the initiation of male sex determination in therian mammals (placental mammals and marsupials). SRY is an intronless sex-determining gene on… Read more.
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Staphylokinase聽(SAK) aka staphylococcal聽fibrinolysin聽or M眉ller’s factor
Staphylokinase聽(SAK; also known as staphylococcal聽fibrinolysin聽or M眉ller’s factor) is a聽protein聽produced by聽Staphylococcus aureus. It contains 136 amino acid residues and has a molecular mass of 15kDa. Synthesis of staphylokinase occurs in late… Read more.
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Paracetamol (acetaminophen) use in infants and children was never shown to be safe for neurodevelopment: a systematic review with citation tracking
Although widely believed by pediatricians and parents to be safe for use in infants and children when used as directed, increasing evidence indicates that early life exposure to paracetamol (acetaminophen)… Read more.
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Prenatal exposure to paracetamol/acetaminophen and precursor aniline impairs masculinisation of male brain and behaviour
Paracetamol/acetaminophen (N-Acetyl-p-Aminophenol; APAP) is the preferred analgesic for pain relief and fever during pregnancy. It has therefore caused concern that several studies have reported that prenatal exposure to APAP results… Read more.
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Agrin聽is a large聽chimeric proteoglycan, a heparan sulfate and chondroitin proteoglycan,聽whose best-characterised role is in the development of the聽neuromuscular junction聽during聽embryogenesis
Agrin was originally found in the electric organ of Tarpedo california and in the basal lamina at the neuromuscular junction as a protein that directs the aggregation of acetylcholine receptors (AChR) and acetylcholinesterase (AChE) at synaptic sites. Tetronarce californica also known as… Read more.
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Adenosine
Adenosine (symbol A) is an organic compound that occurs widely in nature in the form of diverse derivatives. The molecule consists of an adenine attached to a ribose via a 尾-N9–glycosidic bond. Adenosine is one of the four nucleoside building… Read more.
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Proline and a few other notes
Proline (symbol Pro or P) is an organic acid classed as a proteinogenic amino acid (used in the biosynthesis of proteins), although it does not contain the amino group -NH2 but is rather a secondary amine. The secondary amine nitrogen is in… Read more.
