Category: CREATURES

  • Dr. Leo Stanley

    Dr. Leo Stanley

    Let it be known throughout the land that Dr. Leo Leonidas Stanley, a man of most peculiar proclivities, did preside over San Quentin’s medical realm from the year of our Lord 1913 to 1951. This self-proclaimed surgeon, bereft of true surgical experience, did embark upon a crusade most bizarre. With a scalpel in his hand…

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  • Average body temperature dropped every decade since the 1800s and even more every decade since 1960 

    Attention, fellow humans! It’s time to chill out… literally! 🧊 Our bodies are on a cosmic cooldown, and it’s not just because we’ve all become walking popsicles addicted to air conditioning. Oh no, this is far more sinister and hilarious than that! The Great American Refrigeration❄️ Since the 1800s, our core temperatures have been dropping…

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  • Royal Jelly & Silkworm Droppings: The Buzz and the Poop of Traditional Chinese Medicine

    Get ready, because we’re about to dive into the most unhinged yet scientifically fascinating duo in Traditional Chinese Medicine (TCM): Royal Jelly (the queen bee’s secret sauce) and Silkworm Droppings (yes, bug poop, but make it medicinal). These two are the Beyoncé and Jay-Z of the insect-derived health world—unexpected, iconic, and absolutely legendary in their own right. 🐝💩✨ Royal…

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  • the ULTIMATE BUGGY BASS DROP

    Oh snap, buckle up buttercup, ’cause we’re about to dive deep into the wildest rave this side of the exoskeleton! 🐛🎉 Imagine, if you will, a microscopic mosh pit where insects are gettin’ jiggy with it on a molecular level. It’s not your average hormone hoedown, oh no – this is the ULTIMATE BUGGY BASS…

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  • Evans blue

    Evans blue

    T-1824 or Evans blue, often incorrectly rendered as Evan’s blue, is an azo dye that has a very high affinity for serum albumin. Because of this, it can be useful in physiology in estimating the proportion of body water contained in blood plasma. It fluoresces with excitation peaks at 470 and 540 nm and an emission peak at 680 nm. Evans blue dye has been used as a viability assay on…

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  • Chondrin

    Chondrin is a bluish-white gelatin-like substance, being a protein–carbohydrate complex and can be obtained by boiling cartilage in water. The cartilage is a connective tissue that contains cells embedded in a matrix of chondrin. Chondrin is made up of two proteins  See also External links Charles Darwin – Insectivorous Plants Page 56 (added below minus the milk section) Categories:  I therefore wished to…

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  • Dermatan sulfate (and a few other things)

    Dermatan sulfate is a glycosaminoglycan (formerly called a mucopolysaccharide) found mostly in skin, but also in blood vessels, heart valves, tendons, and lungs. It is also referred to as chondroitin sulfate B, although it is no longer classified as a form of chondroitin sulfate by most sources. The formula is C14H21NO15S. This carbohydrate is composed of linear polymers of disaccharide units that contain, N-acetyl galactosamine (GalNAc) and iduronic…

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  • Chondroitin sulfate

    CHONDROITIN SULFATE is a sulfated glycosaminoglycan (GAG) composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid). It is usually found attached to proteins as part of a proteoglycan. A chondroitin chain can have over 100 individual sugars, each of which can be sulfated in variable positions and quantities. Chondroitin sulfate is an important structural component of cartilage, and provides much of its…

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  • Methaemalbumin in Man (1939)

    Methaemalbumin in Man (1939)

    (Pseudo-methaemoglobin) Section of Therapeutics and Pharmacology and a list of related articles

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  • Buggy Love Potion: The Science of Insect Sex Hormones

    Listen up, you sexy six-legged sirens and alluring arthropods! 🐞💋 Get ready to have your mind blown and your exoskeleton rocked. Insect sex hormones: They’re real, they’re spectacular, and they’re changing the game of love in the miniature world! From ecdysone’s double life to gonadotropins’ matchmaking skills, these hormones are the unsung heroes of insect…

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  • Sex-determining region Y protein (SRY), or testis-determining factor (TDF)

    Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that is responsible for the initiation of male sex determination in therian mammals (placental mammals and marsupials). SRY is an intronless sex-determining gene on the Y chromosome. Mutations in this gene lead to a range of disorders of sex development with varying effects on an individual’s phenotype and genotype. SRY is a member of the SOX (SRY-like box)…

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  • DAX1

    DAX1 (dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1) is a nuclear receptor protein that in humans is encoded by the NR0B1 gene (nuclear receptor subfamily 0, group B, member 1). The NR0B1 gene is located on the short (p) arm of the X chromosome between bands Xp21.3 and Xp21.2, from base pair 30,082,120 to base pair 30,087,136. Function This gene encodes a protein…

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  • DMRT1

    Doublesex and mab-3 related transcription factor 1, also known as DMRT1, is a protein which in humans is encoded by the DMRT1 gene. Function DMRT1 is a dose sensitive transcription factor protein that regulates Sertoli cells and germ cells. The DMRT1 gene is located at the end of the 9th chromosome. This gene is found in a cluster with two other members…

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  • DMT1 aka DCT1 and NRAMP2

    Natural resistance-associated macrophage protein 2 (NRAMP 2), also known as divalent metal transporter 1 (DMT1) and divalent cation transporter 1 (DCT1), is a protein that in humans is encoded by the SLC11A2 (solute carrier family 11, member 2) gene. DMT1 represents a large family of orthologous metal ion transporter proteins that are highly conserved from bacteria to humans. As its name suggests, DMT1 binds a variety of divalent metals…

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  • Steroidogenic factor 1 (SF-1) protein and a few related things

    The steroidogenic factor 1 (SF-1) protein is a transcription factor involved in sex determination by controlling the activity of genes related to the reproductive glands or gonads and adrenal glands. This protein is encoded by the NR5A1 gene, a member of the nuclear receptor subfamily, located on the long arm of chromosome 9 at position 33.3. It was originally identified as a regulator of genes encoding cytochrome P450 steroid hydroxylases, however, further roles…

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  • The neonatal fragment crystallizable (Fc) receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans is encoded by the FCGRT gene

    It is an IgG Fc receptor which is similar in structure to the MHC class I molecule and also associates with beta-2-microglobulin. In rodents, FcRn was originally identified as the receptor that transports maternal immunoglobulin G (IgG) from mother to neonatal offspring via mother’s milk, leading to its name as the neonatal Fc receptor. In humans, FcRn is present in the placenta where…

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