ADAM33: The Asthma Whisperer
ADAM33 is the protein that's been keeping pulmonologists up at night! ADAM33 is like that mysterious neighbor who everyone suspects is up to something, but no one can quite figure out what. This sneaky little protein has been linked to asthma,
Tracheal cytotoxin (TCT) is a soluble piece of peptidoglycan (PGN) found in the cell wall of all gram-negative bacteria, but only some bacteria species release TCT including Bordetella pertussis, Vibrio fischeri, and Neisseria gonorrhoeae
Tracheal cytotoxin (TCT) is a 921 dalton glycopeptide released by Bordetella pertussis, Vibrio fischeri (as a symbiosis chemical), and Neisseria gonorrhoeae (among other peptidoglycan-derived cytotoxins it produces). Cundell, DR; Kanthakumar, K; Taylor, GW; Goldman, WE; Flak, T; Cole, PJ; Wilson, R (1994). "Effect of tracheal cytotoxin from Bordetella pertussis on human neutrophil function in