The neonatal fragment crystallizable (Fc) receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans is encoded by the FCGRT gene
It is an IgG Fc receptor which is similar in structure to the MHC class I molecule and also associates with beta-2-microglobulin. In rodents, FcRn was originally identified a
Elevated alpha-fetoprotein
Elevated alpha-fetoprotein refers to a state where alpha-fetoprotein levels are outside of the reference range. There are two categories of AFP tests: tests performed on serum
Smoking is associated with a reduced risk of hypertension during pregnancy
The puzzling association between smoking and hypertension during pregnancy Zhang J, Klebanoff MA, Levine RJ, Puri M, Moyer P. The puzzling association between smoking and hypertens
Microsomal prostaglandin E synthase-1 (mPGES-1)
Microsomal prostaglandin E synthase-1 (mPGES-1) or Prostaglandin E synthase is an enzyme that in humans is encoded by the PTGES gene. The protein encoded by this gene is a g
Microfold cells (or M cells)
Microfold cells (or M cells) are found in the gut-associated lymphoid tissue (GALT) of the Peyer’s patches in the small intestine, and in t
Thunderstones in European Folklore
In Scandinavia thunderstones were frequently worshiped as family gods who kept off spells and witchcraft. Beer was poured over them as an offering, and they were sometimes an
Cells in the APUD system may include Juxtaglomerular cells (JG cells), the renin producing cells in the kidney
Juxtaglomerular cells (JG cells), also known as juxtaglomerular granular cells are cells in the kidney that synthesize, store, and secrete the enzyme renin. They are specia
CBP and p300 are critical for normal embryonic development
Mouse models CBP and p300 are critical for normal embryonic development, as mice completely lacking either CBP or p300 protein, die at an early embryonic stage. In addition, mice
Decreased concentrations of CBP and lower amounts of H3 and H4 acetylation associated with fetal alcohol spectrum disorders
Fetal alcohol spectrum disorders (FASD) is a classification of diseases that all result from alcohol exposure during pregnancy. Symptoms of these disorders include poor cerebella