ADAM24 is the protein that’s giving sperm their cutting edge! ADAM24, also known as Testase 1, is the James Bond of the sperm world. This plasma membrane-anchored protease is found exclusively on mature sperm, ready to spring into action when duty calls1. It’s believed to play a crucial role inContinue Reading

ADAM23 is the protein that’s making waves in the world of neuroscience. ADAM23 is like that friend who’s always helping you find your way around a new city. This protein is highly expressed in the central nervous system and plays a crucial role in brain development1. Picture ADAM23 as theContinue Reading

ADAM22 is a unique member of the ADAM family, primarily expressed in the brain. Unlike many of its relatives, ADAM22 is a non-catalytic metalloprotease-like protein, meaning it lacks proteolytic activity4. Picture ADAM22 as the bouncer at an exclusive neural nightclub. It’s involved in regulating cell adhesion and spreading, and itContinue Reading

ADAM8 is the protein that’s stirring up trouble in your immune system! ADAM8 is like that friend who always shows up when there’s drama brewing. This protein is primarily expressed in immune cells, making it a key player in inflammatory responses. Picture ADAM8 as the bouncer of the cellular world.Continue Reading

ADAM31 is the protein that’s playing hide-and-seek with human geneticists! ADAM31 is like that distant cousin who only shows up at family reunions in other countries. While it’s a well-known member of the ADAM family in mice, it’s conspicuously absent from the human genome. In mice, ADAM31 is expressed inContinue Reading

Prepare to be mystified by ADAM34, the protein that’s playing an elaborate game of hide-and-seek with scientists! ADAM34 is like that elusive celebrity who everyone’s heard of, but no one’s actually seen. This protein is shrouded in mystery, with researchers still debating its very existence in humans. It’s been spottedContinue Reading