Category: Nutrition

  • Konzo is an epidemic paralytic disease reportedly from simultaneous malnutrition and high dietary cyanide intake

    Konzo is an epidemic paralytic disease reportedly from simultaneous malnutrition and high dietary cyanide intake

    Konzo is an epidemic paralytic disease occurring among hunger-stricken rural populations in Africa where a diet dominated by insufficiently processed cassava results in simultaneous malnutrition and high dietary cyanide intake.  Konzo was first described by Giovanni Trolli in 1938 who compiled the observations from eight doctors working in the Kwango area of the Belgian Congo (now Democratic Republic of the Congo). “Konzo” means “tied legs” in…

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  • CBP has intrinsic acetyltransferase functions

    Cyclic adenosine monophosphate Response Element Binding protein Binding Protein (CREB-binding protein), also known as CREBBP or CBP or KAT3A, is a coactivator encoded by the CREBBP gene in humans, located on chromosome 16p13.3. CBP has intrinsic acetyltransferase functions; it is able to add acetyl groups to both transcription factors as well as histone lysines, the latter of which has been shown to alter chromatin structure making genes more accessible for transcription. This relatively…

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  • The Poisonous Pulse of Vapniarka: Grasspea, Lathyrism, and the Holocaust’s Forgotten Horror

    The Poisonous Pulse of Vapniarka: Grasspea, Lathyrism, and the Holocaust’s Forgotten Horror

    During the Second World War, amidst the atrocities of the Holocaust, a little-remembered but harrowing chapter unfolded in the Vapniarka concentration camp in Transnistria. Here, under the command of Colonel Ioan Murgescu, over 1,000 Jewish detainees were subjected to a cruel experiment in survival: they were fed almost exclusively on Lathyrus sativus, or grass pea, a…

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  • Lysine Tyrosylquinone (LTQ)

    Lysine Tyrosylquinone (LTQ)

    LTQ does not have a wikipedia page so I will check elsewhere. In the meantime, I found another reason to just say no to beans – osteolathyrism aka odoratism, which is a form of the disease Lathyrism. Wikipedia says: The disease results from the ingestion of Lathyrus odoratus seeds (sweet peas) from the family Fabaceae (legumes). The toxin found in the sweet peas is…

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  • Oxalyldiaminopropionic acid (ODAP) is a structural analogue of the neurotransmitter glutamate found in the grass pea Lathyrus sativus

    Oxalyldiaminopropionic acid (ODAP) is a structural analogue of the neurotransmitter glutamate found in the grass pea Lathyrus sativus. It is the neurotoxin responsible for the motor neuron degeneration syndrome lathyrism. Woldeamanuel, Yohannes W.; Hassan, Anhar; Zenebe, Guta (2011-11-12). “Neurolathyrism: two Ethiopian case reports and review of the literature”. Journal of Neurology. 259 (7): 1263–1268. doi:10.1007/s00415-011-6306-4. ISSN 0340-5354. PMID 22081101. S2CID 27543906. Sources ODAP is found in the seeds of the legume L. sativus, a grass pea…

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  • The sweet pea is a flowering plant in the genus Lathyrus in the family Fabaceae (legumes)  🧪☣️☠️⚗️🤢

    The sweet pea is a flowering plant in the genus Lathyrus in the family Fabaceae (legumes)  🧪☣️☠️⚗️🤢

    The sweet pea, Lathyrus odoratus, is a flowering plant in the genus Lathyrus in the family Fabaceae (legumes), native to Sicily, southern Italy and the Aegean Islands. It is an annual climbing plant, growing to a height of 1–2 metres (3 ft 3 in – 6 ft 7 in), where suitable support is available. The leaves are pinnate with two leaflets and a terminal tendril, which twines around supporting plants and structures, helping the sweet pea to climb. In…

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