Category: Bad Medicine
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Fischer-Fantuzzi L, Vesco C. Deletion of 43 amino acids in the NH2-terminal half of the large tumor antigen of simian virus 40 results in a non-karyophilic protein capable of transforming established cells. Proc Natl Acad Sci U S A. 1985
Abstract We have characterized a simian virus 40 (SV40) mutant, derived from the viral DNA insertion present in simian cell transformants, which carries a deletion affecting the NH2-terminal region of the SV40 large tumor antigen. This mutant protein is 6% smaller than normal, has lost the typical nuclear localization of the SV40 large tumor antigen,…
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Nucleus accumbens aka accumbens nucleus
The nucleus accumbens (NAc or NAcc; also known as the accumbens nucleus, or formerly as the nucleus accumbens septi, Latin for “nucleus adjacent to the septum“) is a region in the basal forebrain rostral to the preoptic area of the hypothalamus. The nucleus accumbens and the olfactory tubercle collectively form the ventral striatum. The ventral striatum and dorsal striatum collectively form the striatum, which is the main component of the basal ganglia. The dopaminergic neurons of the mesolimbic pathway project onto the GABAergic medium…
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Enterohepatic circulation
Enterohepatic circulation refers to the circulation of biliary acids, bilirubin, drugs or other substances from the liver to the bile, followed by entry into the small intestine, absorption by the enterocyte and transport back to the liver. Enterohepatic circulation is an especially important concept in the field of toxicology as many lipophilic xenobiotics undergo this process causing repeated liver damage. Enterohepatic circulation allows for recycling of metabolized and non-metabolized compounds,…
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Sonification
Sonification is the use of non-speech audio to convey information or perceptualize data. Auditory perception has advantages in temporal, spatial, amplitude, and frequency resolution that open possibilities as an alternative or complement to visualization techniques. For example, the rate of clicking of a Geiger counter conveys the level of radiation in the immediate vicinity of the device. Though many experiments with data sonification have been explored in forums…
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🝖 Alchemical Symbol For Horse Dung
Ah, the alchemical symbol for horse dung! Let’s gallop into this steaming pile of esoteric wisdom, shall we? 🐎💩✨ Picture this: An alchemist, eyes wild with the fever of discovery, realizes that the key to unlocking the universe’s secrets lies not in rare metals or exotic herbs, but in the humble excrement of Equus ferus…
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What is Immunoprecipitation (IP)?
Immunoprecipitation (IP) is a technique used to enrich protein antigens from a complex mixture using specific antibodies. To carry out an IP, antibodies must be coupled to a solid substrate, such as agarose resin or magnetic beads, to allow for purification of the target antigens. Immunoprecipitation (IP) is the technique of precipitating a protein antigen out of solution using an antibody that…
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Symbols for Sulfur and Mercury
Symbols for sulfur and mercury 1F70D 🜍 ALCHEMICAL SYMBOL FOR SULFUR = brimstone 1F70E 🜎 ALCHEMICAL SYMBOL FOR PHILOSOPHERS SULFUR 1F70F 🜏 ALCHEMICAL SYMBOL FOR BLACK SULFUR = sulfur nigra, dye 1F710 🜐 ALCHEMICAL SYMBOL FOR MERCURY SUBLIMATE → 263F ☿ mercury → 1F75E 🝞 alchemical symbol for sublimation…
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Ceres, Roman goddess
In ancient Roman religion, Ceres was a goddess of agriculture, grain crops, fertility and motherly relationships. She was originally the central deity in Rome’s so-called plebeian or Aventine Triad, then was paired with her daughter Proserpina in what Romans described as “the Greek rites of Ceres”. Her seven-day April festival of Cerealia included the popular Ludi Ceriales (Ceres’ games). She was also honoured in the May lustration (lustratio) of the fields at the Ambarvalia festival: at…
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Keres, bloodthirsty death spirits in Greek Mythology
In Greek mythology, the Keres (/ˈkɪriːz/; Ancient Greek: Κῆρες), singular Ker (/ˈkɜr/; Κήρ), were female death-spirits. They were the goddesses who personified violent death and who were drawn to bloody deaths on battlefields. Although they were present during death and dying, they did not have the power to kill. All they could do was wait and then feast on the dead. The…
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A columbarium is a structure for the reverential and usually public storage of funerary urns holding cremains of the dead
A columbarium (pl. columbaria) is a structure for the reverential and usually public storage of funerary urns holding cremains of the dead. The term comes from the Latin columba (dove) and originally solely referred to compartmentalized housing for doves and pigeons, also called dovecotes. Background Roman columbaria were often built partly or completely underground. The Columbarium of Pomponius Hylas is an ancient Roman example, rich in frescoes, decorations, and…
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Brno Ossuary holds the remains of over 50 thousand people
Brno Ossuary is an underground ossuary in Brno, Czech Republic. It was rediscovered in 2001 in the historical centre of the city, partially under the Church of St. James. It is estimated that the ossuary holds the remains of over 50 thousand people which makes it the second-largest ossuary in Europe, after the Catacombs of Paris. The ossuary was founded in the 17th century,…
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Memento mori (symbolic trope)
Memento mori (Latin for ‘remember that you [have to] die’) is an artistic or symbolic trope acting as a reminder of the inevitability of death. The concept has its roots in the philosophers of classical antiquity and Christianity, and appeared in funerary art and architecture from the medieval period onwards. The most common motif is a skull, often accompanied by one or more bones. Often this alone is…
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Secondary burial is a feature of prehistoric and historic gravesites which refers to an exhumation and reburial
The secondary burial (German: Nachbestattung or Sekundärbestattung), or “double funeral” (not to be confused with double burial in which two bodies are interred together) is a feature of prehistoric and historic gravesites. The term refers to remains that represent an exhumation and reburial, whether intentional or accidental. Examples of secondary burial are known from the Paleolithic period, (including the Middle Paleolithic Mousterian culture and the Upper Paleolithic Magdalenian culture) and continuing through the Mesolithic period into the Neolithic period. The…
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Saint-Lazare Prison was originally a leprosarium and then a prison and then a hospital now marked by the Church of Saint-Vincent-de-Paul
Saint-Lazare Prison was a prison in the 10th arrondissement of Paris, France. History Originally a leprosarium was founded on the road from Paris to Saint-Denis at the boundary of the marshy area of the former River Seine bank in the 12th century. It was ceded on 7 January 1632 to St. Vincent de Paul and the Congregation of the Mission he had founded. At this stage, it became a place…
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Dis Pater aka Rex Infernus, Roman god of the underworld, contracted from Dives Pater (“Father of Riches”)
Dīs Pater (Dītis Patris), otherwise known as Rex Infernus or Pluto, is a Roman god of the underworld. Dis was originally associated with fertile agricultural land and mineral wealth, and since those minerals came from underground, he was later equated with the chthonic deities Pluto (Hades) and Orcus. Dīs Pater’s name was commonly shortened to Dīs, and this name has since become an alternative name for the underworld or a part…
