ParacetamolTobacco🜺 Arsenic (and Old Leeches)
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Some smokers show fewer symptoms or appear less affected by certain toxins — arsenic included — at doses that harm nonsmokers. This isn’t protection in the traditional sense. It’s more like biochemical compensation or adaptive masking. 🔄 Possible Mechanisms Behind the Paradox Induced Detox Enzymes: Chronic exposure to smoke mayContinue Reading

AminosaursAspartameBiotinEggsFood supplementsHairParacetamol
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Isoleucine (symbol Ile or I) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+3 form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO− form under biological conditions), and a hydrocarbon side chain with a branch (a central carbon atom bound to three other carbon atoms). It is classified as a non-polar, uncharged (atContinue Reading

AspartameParacetamol
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Reference for subtitle: Finamor IA, Bressan CA, Torres-Cuevas I, Rius-Pérez S, da Veiga M, Rocha MI, Pavanato MA, Pérez S. Long-Term Aspartame Administration Leads to Fibrosis, Inflammasome Activation, and Gluconeogenesis Impairment in the Liver of Mice. Biology. 2021; 10(2):82. https://doi.org/10.3390/biology10020082 NLR family pyrin domain containing 3 (NLRP3) (previously known as NACHT,Continue Reading

AspartameParacetamol
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Glutathione Local Links Nuclear factor erythroid 2-related factor 1 Local Links Reference for subtitle: Finamor IA, Bressan CA, Torres-Cuevas I, Rius-Pérez S, da Veiga M, Rocha MI, Pavanato MA, Pérez S. Long-Term Aspartame Administration Leads to Fibrosis, Inflammasome Activation, and Gluconeogenesis Impairment in the Liver of Mice. Biology. 2021; 10(2):82.Continue Reading

AspartameNeuroscienceParacetamol
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Although widely believed by pediatricians and parents to be safe for use in infants and children when used as directed, increasing evidence indicates that early life exposure to paracetamol (acetaminophen) may cause long-term neurodevelopmental problems. Furthermore, recent studies in animal models demonstrate that cognitive development is exquisitely sensitive to paracetamolContinue Reading

AnilineAzo dyesBrain developmentIndigoMaleNeuroendocrinologyParacetamol
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Paracetamol/acetaminophen (N-Acetyl-p-Aminophenol; APAP) is the preferred analgesic for pain relief and fever during pregnancy. It has therefore caused concern that several studies have reported that prenatal exposure to APAP results in developmental alterations in both the reproductive tract and the brain. Genitals and nervous system of male mammals are activelyContinue Reading

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Studies report that fetal exposure to paracetamol/acetaminophen by maternal consumption can interfere with male reproductive development. Moreover, recent biomonitoring data report widespread presence of paracetamol in German and Danish populations, suggesting exposure via secondary (nonpharmaceutical) sources, such as metabolic conversion from the ubiquitous industrial compound aniline. In this study, weContinue Reading

Azo dyesHormonesIndigoMaleParacetamolSexology
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Industrial use of aniline is increasing worldwide with production estimated to surpass 5.6 million metric tons in 2016. Exposure to aniline occurs via air, diet, and water augmenting the risk of exposing a large number of individuals. Early observations suggest that aniline is metabolized to paracetamol/acetaminophen, likely explaining the omnipresenceContinue Reading

Bad FoodBad MedicineDogHeparinLipopolysaccharideParacetamolPiss ProphecyTobaccoZinc
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Glucuronic acid (from Greek γλεῦκος “wine, must” and οὖρον “urine“) is a uronic acid that was first isolated from urine (hence the name”uronic acid”). It is found in many gums such as gum arabic (approx. 18%), xanthan, and kombucha tea and is important for the metabolism of microorganisms, plants and animals. Not to be confused with Gluconic acid (Gluconic acid occurs naturally in fruit, honey, and wine. As a food additive E574, it isContinue Reading

Accessory Digestive OrgansEnterohepatic CirculationParacetamol
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Enterohepatic circulation refers to the circulation of biliary acids, bilirubin, drugs or other substances from the liver to the bile, followed by entry into the small intestine, absorption by the enterocyte and transport back to the liver. Enterohepatic circulation is an especially important concept in the field of toxicology as many lipophilic xenobiotics undergo this process causing repeated liver damage. Enterohepatic circulation allows for recyclingContinue Reading

BambooBeechParacetamolPlant ToxinsSpruceSticks and Stones
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Piceol is a phenolic compound found in the needles and in mycorrhizal roots of Norway spruces (Picea abies). Picein is the glucoside of piceol. Pungenin is a also phenolic compound found in the needles of Blue Spruce (Picea pungens). It is the glucoside of 3,4-dihydroxyacetophenone. The compound serves a feeding deterrent against Spruce Budworm larvae. This may be a little redundant as the base information is alreadyContinue Reading

BaccharisBeeBiological PigmentsCattleParacetamolPlant ToxinsSilver
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They are commonly known as baccharises but sometimes referred to as “brooms”, because many members have small thin leaves resembling the true brooms. They are not at all related to these however, but belong to an entirely different lineage of eudicots. B. halimifolia is commonly known as “groundsel bush”, however true groundsels are found in theContinue Reading