Paracetamol is an aniline derivative with a sketchy date of birth (and a very sketchy rebirth)
Paracetamol was first made in 1877…or possibly 1852. Some reports state that Cahn & Hepp or a French chemist called Charles Gerhardt first synthesized paracetamol in 1852
The word “paracetmol”
The word “paracetmol” is a shortened form of para-acetyl-amino-phenol, and was coined, manufactured and sold by Frederick Stearns & Co in 1956.
The word “acetaminophen”
The word “acetaminophen” is a shortened form of N-acetyl aminophenol, and was coined and first marketed by McNeil Laboratories in 1955.
Paracetamol is extremely toxic to cats, which lack the necessary UGT1A6 enzyme to detoxify it
Paracetamol is extremely toxic to cats, which lack the necessary UGT1A6 enzyme to detoxify it. Initial symptoms include vomiting, salivation, and discoloration of the tongue and
N-acetylcysteine treatment is efficacious in dogs when administered within two hours of toxic paracetamol ingestion
Paracetamol has been reported to be as effective as aspirin in the treatment of musculoskeletal pain in dogs. The main effect of toxicity in dogs is liver damage, and GI ulceration
Paracetamol is lethal to snakes
Paracetamol is lethal to snakes, and has been suggested as a chemical control program for the invasive brown tree snake (Boiga irregularis) in Guam. Doses of 80 mg are inserted
Benefits of paracetamol for fever are unclear
Paracetamol (acetaminophen or para-hydroxyacetanilide) is a medication used to treat fever and mild to moderate pain. At a standard dose, paracetamol only slightly decreas
Metoclopramide, Paracetamol/metoclopramide, Witch’s Milk, Lactating Men and Homicidal Maniacs?
Metoclopramide is a medication used for stomach and esophageal problems. It is commonly used to treat and prevent nausea and vomiting,
Anti-thymocyte globulin (ATG)
Anti-thymocyte globulin (ATG) is an infusion of horse or rabbit-derived antibodies against human T cells and their precursors (thymocytes), which is used in the prevention and t
Prolactin receptor modulators
Prolactin Agonists An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to m
What Is Nitrophenol? (besides something mentioned in ‘Scientific Opinion on the re‐evaluation of aspartame as a food additive’)
Nitrophenols are compounds of the formula HOC6H5−x(NO2)x. The conjugate bases are called nitrophenolates. Nitrophenols are more acidic than phenol itself. Wikipedi
Another reason not to feed pigeons – your food is poison?
I can’t tell you why except they showed up on a wiki search. Climate change has a negative effect on this bird, and reproductive performance decreases with increased temperat