Chrysiasis
Chrysiasis is a dermatological condition induced by the parenteral administration of gold salts, usually for the treatment of rheumatoid arthritis.â Such treatment has been superseded as the best practice for treating the disease because of “numerous side effects and monitoring require
Cathepsin G
Cathepsin G plays an important role in eliminating intracellular pathogens and breaking down tissues at inflammatory sites, as well as in anti-inflammatory response
Acid phosphatase (systematic name phosphate-monoester phosphohydrolase (acid optimum)) is an enzyme that frees attached phosphoryl groups from other molecules during digestion
Acid phosphatase (EC 3.1.3.2, systematic name phosphate-monoester phosphohydrolase (acid optimum)) is an enzyme that frees attached phosphoryl groups from other molecules during digestion. It can be further classified as a phosphomonoesterase. It is stored in lysosomes and functions when these
Sodium aurothiomalate aka gold sodium thiomalate
Sodium aurothiomalate (INN, known in the United States as gold sodium thiomalate) is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Along with an orally-administered gold salt, auranofin, it is one of only two gold compounds currently employed in modern medi
Microsomal prostaglandin E synthase-1 (mPGES-1)
Microsomal prostaglandin E synthase-1 (mPGES-1) or Prostaglandin E synthase is an enzyme that in humans is encoded by the PTGES gene. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinfla
Elastase
In molecular biology, elastase is an enzyme from the class of proteases (peptidases) that break down proteins. In particular, it is a serine protease. Forms and classification Eight human genes exist for elastase: Family Gene symbol Protein name EC number Approved Previous Appro
β-Glucuronidases
For ι-glucuronidase, see alpha-glucuronidase. β-Glucuronidase β-Glucuronidase asymmetric unit showing active site residues Glu451, Tyr504, and Glu540, along with the potentially supporting Asn450 residue Identifiers Symbol GUSB NCBI gene 2990 HGNC 4696 OMIM 611499 RefSeq NM_000181 UniProt P0
Testican
Testican is a type of proteoglycan. Testican-1 is a highly conserved, multidomain proteoglycan that is most prominently expressed in the thalamus, and is upregulated in activated astroglial cells of the cerebrum. Several functions of this gene product have now been demonstra
Lumican aka LUM
Lumican, also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12. Structure Lumican is a proteoglycan Class II member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan
Albumen prints and egg whites…all the rage back in the day…and a few other things
The albumen print, also called albumen silver print, was published in January 1847 by Louis DĂŠsirĂŠ Blanquart-Evrard, and was the first commercially exploitable method of producing a photographic print on a paper base from a negative. It used the albumen foun
p-Phenylenediamine (PPD) is a derivative of aniline used in kevlar, hair dye and henna substitutions among other things, the derivatives of which are used in antiozonants among other horrors
p-Phenylenediamine (PPD) is an organic compound with the formula C6H4(NH2)2. This derivative of aniline is a white solid, but samples can darken due to air oxidation.It is mainly used as a component of engineering polymers and composites like kevlar. It is also an ingredient in hair dyes a
Thunderstones (and Touchstones) in Asian Tradition
In Burma they are used as a cure and preventative for appendicitis. In Japan they cure boils and ulcers. In Malaysia and Sumatra they are used to sharpen the kris, are considered very lucky objects, and have been credited with being touchstones for gold. A touchstone is a small tablet of dark
Von Willebrand factor (VWF) is a large multimeric glycoprotein present in blood plasma and produced constitutively as ultra-large VWF in endothelium (in the WeibelâPalade bodies), megakaryocytes (Îą-granules of platelets), and subendothelial connective tissue
Von Willebrand factor (VWF) is a blood glycoprotein that promotes hemostasis, specifically, platelet adhesion. It is deficient and/or defective in von Willebrand disease and is involved in many other diseases, including thrombotic thrombocytopenic pu
Ectodomain Shedding & Sheddases & a whole bunch of Adams
An ectodomain is the domain of a membrane protein that extends into the extracellular space (the space outside a cell). Ectodomains are usually the parts of proteins that initiate contact with surfaces, which leads to signal transduction. A nota