Category: Endocrine, nutritional and metabolic disease

Parafollicular cells aka C cells secrete calcitonin and several neuroendocrine peptides

Parafollicular cells, also called C cells, are neuroendocrine cells in the thyroid. The primary function of these cells is to secrete calcitonin. They are located adjacent to the thyroid follicles and reside in the connective tissue. These cells are large and have a pale stain compared with the follicular cells. In teleost and avian species these cells occupy a structure outside the thyroid…
Read more...

May 15, 2023
Adenohypophysis regulates several physiological processes, including stress, growth, reproduction, and lactation

A major organ of the endocrine system, the anterior pituitary (also called the adenohypophysis or pars anterior) is the glandular, anterior lobe that together with the posterior lobe (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis). The anterior pituitary regulates several physiological processes, including stress, growth, reproduction, and lactation. Proper functioning of the anterior pituitary and of the organs it regulates can often be ascertained via blood tests that measure hormone levels. Structure The pituitary gland sits in a…
Read more...

May 15, 2023
Inborn error of purine–pyrimidine metabolism

Inborn errors of purine–pyrimidine metabolism are a class of inborn error of metabolism disorders specifically affecting purine metabolism and pyrimidine metabolism. An example is Lesch–Nyhan syndrome. Urine tests may be of use in identifying some of these disorders.[1] Purine metabolism Anabolism Adenylosuccinate lyase deficiency – Adenosine Monophosphate Deaminase Deficiency type 1 Nucleotide salvage Lesch–Nyhan syndrome/Hyperuricemia – Adenine phosphoribosyltransferase deficiency Catabolism Adenosine deaminase…
Read more...

January 3, 2023