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The drug phencyclidine (more commonly known as PCP or 'Angel Dust') antagonizes glutamic acid non-competitively at the NMDA receptor. For the same reasons, dextromethorphan and ketamine also have strong dissociative and hallucinogenic effects. Acute infusion of the drug LY354740 (also known as eglumegad, an agonist of the metabotropic glutamate receptors2 and 3) resulted in a marked diminution of yohimbine-induced stress response in bonnet macaques

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Bad Food, Bad Medicine, Glutamate, Glutamine
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Oxalyldiaminopropionic acid (ODAP) is a structural analogue of the neurotransmitter glutamate found in the grass pea Lathyrus sativus. It is the neurotoxin responsible for the motor neuron degeneration syndrome lathyrism. Woldeamanuel, Yohannes W.; Hassan, Anhar; Zenebe, Guta (2011-11-12). "Neurolathyrism: two Ethiopian case reports and review of the literature". Journal of Neurology. 259 (7): 1263–1268. doi:10.1007/s00415-011-6306-4. ISSN 0340-5354. PMID 22081101. S2CID 27543906. Sources ODAP

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Bad Food, Glutamate, Legumes, Malnutrition
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Tryptophan tryptophylquinone (TTQ) is an enzyme cofactor, generated by posttranslational modification of amino acids within the protein. Methylamine dehydrogenase (MADH), an amine dehydrogenase, requires TTQ for its catalytic function. Davidson, V. L.; Liu, A. (2012). "Tryptophan tryptophylquinone biosynthesis: A radical approach to posttranslational modification, by Victor L. Davidson1 and Aimin Liu2,

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Blood, Copper, Crosslinks between two AAs, Hemeproteins, Iron, Tryptophan–Tryptophylquinone
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Kaede is a photoactivatable fluorescent protein naturally originated from a stony coral, Trachyphyllia geoffroyi. Its name means "maple" in Japanese. With the irradiation of ultraviolet light (350–400 nm), Kaede undergoes irreversible photoconversion from green fluorescence to red fluorescence. Kaede is a homotetrameric protein with the size of 116 kDa. The tetrameric structure was deduced as its primary structure

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Histidine–Tyrosine–Glycine, Three consecutive AAs (chromophore formation)
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Interactive image of nucleic acid structure (primary, secondary, tertiary, and quaternary) using DNA helices and examples from the VS ribozyme and telomerase and nucleosome. (PDB: ADNA, 1BNA, 4OCB, 4R4V, 1YMO, 1EQZ) Nucleic acid secondary structure is the basepairing interactions within a single nucleic acid polymer or between two polymers. It can be represented as a list of bases which are paired in

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Complement, Nucleic acid structure, Secondary

In a chain-like biological molecule, such as a protein or nucleic acid, a structural motif is a common three-dimensional structure that appears in a variety of different, evolutionarily unrelated molecules. Johansson, M.U. (23 July 2012). "Defining and searching for structural motifs using DeepView/Swiss-PdbViewer". BMC Bioinformatics. 13 (173): 173. doi:10.1186/1471-2105-13-173. PMC 3436773. PMID 22823337.  A structural motif does not have to be

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Complement, See also, Structural motif, Zinc
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β turns (also β-bends, tight turns, reverse turns, Venkatachalam turns) are the most common form of turns—a type of non-regular secondary structure in proteins that cause a change in direction of the polypeptide chain. They are very common motifs in proteins and polypeptides.Venkatachalam, CM (1968). "Stereochemical criteria for polypeptides and proteins. V. Conformation

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Extended, Protein Secondary Structure