Identification of cembratriene-4,6-diol as antitumor-promoting agent from cigarette smoke condensate
Yutaka Saito, Haruo Takizawa, Sumie Konishi, Daisuke Yoshida, Shigenobu Mizusaki, Identification of cembratriene-4,6-diol as antitumor-promoting agent from cigarette smoke condensate, Carcinogenesis, Volume 6, Issue 8, August 1985, Pages 1189–1194, https://doi.org/10.1093/carcin/6.8.1189
Tobacco use is negatively associated with the risk of developing skin cancer, prostate cancer, multiple myeloma, endometrial carcinoma, or breast cancer (negatively associated with means less disease associated with)
Impact of tobacco smoking on the risk of developing 25 different cancers in the UK: a retrospective study of 422,010 patients followed for up to 30 years. Jacob L, Freyn M, Kalder M et al (2018) Impact of tobacco smoking on the risk of developing 25 different cancers in the UK: a retrospective study
Evidence of the protective effect of smoking against thyroid cancer
Cigarette smoking and the risk of thyroid cancer. Kreiger N, Parkes R. Cigarette smoking and the risk of thyroid cancer. Eur J Cancer. 2000 Oct;36(15):1969-73. doi: 10.1016/s0959-8049(00)00198-2. PMID: 11000579. Thyroid cancer risk and smoking status: a meta-analysis. Cancer Causes Control Cho YA, K
Cigarette smoking significantly reduces risk of endometrial cancer especially among postmenopausal women
Cigarette smoking and the risk of endometrial cancer: a meta-analysis. Zhou B, Yang L, Sun Q, Cong R, Gu H, Tang N, Zhu H, Wang B. Cigarette smoking and the risk of endometrial cancer: a meta-analysis. Am J Med. 2008 Jun;121(6):501-508.e3. doi: 10.1016/j.amjmed.2008.01.044. PMID: 18501231.
Smoking is associated with a reduced risk of hypertension during pregnancy
The puzzling association between smoking and hypertension during pregnancy Zhang J, Klebanoff MA, Levine RJ, Puri M, Moyer P. The puzzling association between smoking and hypertension during pregnancy. Am J Obstet Gynecol. 1999 Dec;181(6):1407-13. doi: 10.1016/s0002-9378(99)70384-4. PMID: 10601921.
Evidence that cigarette smoking is associated with lower uterine leiomyomata incidence
A prospective ultrasound study of cigarette smoking and uterine leiomyomata incidence and growth Wesselink AK, Wegienka G, Coleman CM, Geller RJ, Harmon QE, Upson K, Lovett SM, Claus Henn B, Marsh EE, Noel NL, Baird DD, Wise LA. A prospective ultrasound study of cigarette smoking and uterine leiomyo
Pharmacologically, nicotine acts on cholinergic (nicotinic-specific) receptors which are depleted in AD and PD. Nicotinic receptors also interact closely with several neurotransmitters including dopamine, which is implicated in both PD and Gilles de la Tourettes’s syndrome
Does nicotine have beneficial effects in the treatment of certain diseases? Birtwistle J, Hall K. Does nicotine have beneficial effects in the treatment of certain diseases? Br J Nurs. 1996 Oct 24-Nov 13;5(19):1195-202. doi: 10.12968/bjon.1996.5.19.1195. PMID: 9006184.
Three mechanisms predominate for beneficial effects of smoking: the ‘anti-estrogenic effect’ of smoking; alterations in prostaglandin production; and stimulation of nicotinic cholinergic receptors in the central nervous system
Beneficial effects of nicotine and cigarette smoking: the real, the possible and the spurious Baron JA. Beneficial effects of nicotine and cigarette smoking: the real, the possible and the spurious. Br Med Bull. 1996 Jan;52(1):58-73. doi: 10.1093/oxfordjournals.bmb.a011533. PMID: 8746297.
Smoking is beneficial against Parkinson’s, Alzheimer’s, allergic alveolitis, nausea and vomiting of pregnancy, pre-eclampsia, fibroids, carcinoma of body of uterus, ulcerative colitis, pyoderma gangrenosum, aphthous stomatitis and ulceration, pemphigus, herpes simplex and acne
Smoking can be good for you Wolf R, Orion E, Matz H, Maitra S, Rowland-Payne C. Smoking can be good for you. J Cosmet Dermatol. 2004 Apr;3(2):107-11. doi: 10.1111/j.1473-2130.2004.00069.x. PMID: 17147565.
Primary sclerosing cholangitis, like ulcerative colitis, is a disease of non-smokers as the odds of having PSC are significantly decreased among current and former smokers
Cigarette smoking, appendectomy, and tonsillectomy as risk factors for the development of primary sclerosing cholangitis: a case control study Mitchell SA, Thyssen M, Orchard TR, Jewell DP, Fleming KA, Chapman RW. Cigarette smoking, appendectomy, and tonsillectomy as risk factors for the development
Smoking cessation significantly raises risk and incidence of type-2 diabetes and obstructive pulmonary disease
Study shows increased risk of diabetes after smoking cessation lasts for 12 years Yeh HC, Duncan BB, Schmidt MI, Wang NY, Brancati FL. Smoking, smoking cessation, and risk for type 2 diabetes mellitus: a cohort study. Ann Intern Med. 2010 Jan 5;152(1):10-7. doi: 10.7326/0003-4819-152-1-201001050-000
Glucuronic acid is a uronic acid that was first isolated from urine
Glucuronic acid (from Greek γλεῦκος “wine, must” and οὖρον “urine“) is a uronic acid that was first isolated from urine (hence the name”uronic acid”). It is found in many gums such as gum arabic