Tag: ASPARTAME
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Dulcin, toxic artificial sweetener about 250 times sweeter than sugar
Dulcin is an artificial sweetener about 250 times sweeter than sugar, discovered in 1883 by the Polish chemist Józef (Joseph) Berlinerblau (27 August 1859 – 1935). It was first mass-produced about seven years later. Although it was discovered only five years after saccharin, it never enjoyed the latter compound’s market success. Nevertheless, it was an important sweetener of the early 20th…
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Metoclopramide, Paracetamol/metoclopramide, Witch’s Milk, Lactating Men and Homicidal Maniacs?
Metoclopramide is a medication used for stomach and esophageal problems. It is commonly used to treat and prevent nausea and vomiting, to help with emptying of the stomach in people with delayed stomach emptying, and to help with gastroesophageal reflux disease. It is also used to treat migraine headaches. Common side effects include: feeling tired, diarrhea, and feeling restless. More serious side effects include: movement disorder like tardive dyskinesia, a condition called neuroleptic malignant…
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Dicoumarol (Moldy Sweet Clover) Toxicosis in a Group of Holstein Calves
Yamini B, Poppenga RH, Emmett BW, Judge LJ. Dicoumarol (Moldy Sweet Clover) Toxicosis in a Group of Holstein Calves. Journal of Veterinary Diagnostic Investigation. 1995;7(3):420-422. doi:10.1177/104063879500700328 References 1. Alstad AD, Casper HH, Johnson LJ: 1985, Vitamin K treatment of sweet clover poisoning in calves. J Am Vet Med Assoc 187:729–731. 2. Blakley BR: 1985, Moldy sweet clover (dicoumarol) poisoning in…
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Tetragastrin is commonly used in scientific research to induce panic attacks
CCK-4 reliably causes severe anxiety symptoms when administered to humans in a dose of as little as 50μg
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Several high-ranking government officials closely tied to the approval and subsequent defense of aspartame took jobs in the NutraSweet industry
U.S. Attorney Samuel Skinner went to work for Sidley & Austin, G.D. Searle’s law firm. Assistant U.S. Attorney William Conlon went to work for Sidley & Austin. H.R. Roberts, director of the FDA’s Bureau of Food took a job as vice president of the National Soft Drink Assoc. After an unsuccessful bid in the late…
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After an unsuccessful bid in the late ’70s, G.D. Searle reapplied for FDA approval of aspartame the day after Ronald Reagan was inaugurated.
G.D. Searle CEO Donald Rumsfeld served as a key member of Reagan’s transition team. In April 1981 From Sweetheart Deal Thoughts for another day: Rumsfeld – ‘Valiant Thor’? 🤨
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What Is Metalloproteinase?
Metalloproteinase – the name alone screams “I’m here to ruin everything” – is a feral pack of enzymes armed with metal claws (zinc, mostly, because it’s the shiniest weapon in the elemental arsenal) that shred proteins like they’re auditioning for a slasher flick. These molecular psychopaths don’t just cut – they obliterate, turning the extracellular…
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What Is Nitrophenol? (besides something mentioned in ‘Scientific Opinion on the re‐evaluation of aspartame as a food additive’)
Nitrophenols are compounds of the formula HOC6H5−x(NO2)x. The conjugate bases are called nitrophenolates. Nitrophenols are more acidic than phenol itself. Wikipedia Mono-nitrophenols with the formula HOC6H4NO2. Three isomeric nitrophenols exist: o-Nitrophenol (2-nitrophenol; OH and NO2 groups are neighboring; CAS number: 88-75-5), a yellow crystalline solid (m.p. 46 °C). m-Nitrophenol (3-nitrophenol, CAS number: 554-84-7), a yellow solid (m.p. 97 °C) and precursor to the…
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Another reason not to feed pigeons – your food is poison?
I can’t tell you why except they showed up on a wiki search. Climate change has a negative effect on this bird, and reproductive performance decreases with increased temperatures. It is also particularly vulnerable to oil, and adults near oiled shores display symptoms of hepatocellular injury, where elevated levels of aspartate aminotransferase can be found in the liver. Otherwise,…
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Haldol: The Grim Reaper’s Sidekick
Haloperidol, better known as Haldol, is not just a drug—it’s a cultural artifact of medicine’s darker corners. It has worn many hats: psychiatric savior, hospice workhorse, veterinary tranquilizer, and even a lurking specter in the shadowy world of death cocktails. This report dives deep into the multifaceted (and occasionally unsettling) life of Haldol, from its…
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4-Nitrophenol mentioned in ‘Scientific Opinion on the re‐evaluation of aspartame (E 951) as a food additive’ (2013)
3.2.6.2. Studies on the effect of aspartame administration on xenobiotic metabolising enzymesAn early study (E15, 1972) indicated that the oral administration of aspartame to male Charles River rats (2000-4000 mg/kg) for four days had no acute effect on hepatic cytochrome P450 (CYP)-mediated xenobiotic metabolism, as measured as aminopyrine N-demethylation, p-nitroanisole Ndemethylation, hexobarbital sleeping time or…
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Aspartame was discovered by James M. Schlatter (1930 – 2019)
Lead chemist and developer of Aspartame used to make NutraSweet and Equal artificial sweeteners
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Torunn Atteraas Garin (1947 – 2002)
Norwegian chemical engineer who helped develop aspartame sweetener as a sugar substitute while working for General Foods (1971-85)
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Green synthesis of gold nanoparticles using aspartame and their catalytic activity for p-nitrophenol reduction
Wu S, Yan S, Qi W, Huang R, Cui J, Su R, He Z. Green synthesis of gold nanoparticles using aspartame and their catalytic activity for p-nitrophenol reduction. Nanoscale Res Lett. 2015 May 8;10:213. doi: 10.1186/s11671-015-0910-7. PMID: 25991916; PMCID: PMC4431991. Abstract We demonstrated a facile and environmental-friendly approach to form gold nanoparticles through the reduction…
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