Tag: ASPARTATE

  • Kynureninase or L-Kynurenine hydrolase (KYNU) is part of the pathway for the catabolism of Trp and the biosynthesis of NAD cofactors from tryptophan (Trp).

    Kynureninase or L-Kynurenine hydrolase (KYNU) is part of the pathway for the catabolism of Trp and the biosynthesis of NAD cofactors from tryptophan (Trp).

    Kynureninase or L-Kynurenine hydrolase (KYNU) (EC 3.7.1.3) is a PLP dependent enzyme that catalyses the cleavage of kynurenine (Kyn) into anthranilic acid (Ant). It can also act on 3-hydroxykynurenine (to produce 3-hydroxyanthranilate) and some other (3-arylcarbonyl)-alanines. Note: 3-Hydroxykynurenine is a metabolite of tryptophan, which filters UV light in the human lens. It is one of two pigments identified as responsible for the goldenrod crab spider‘s (Misumena vatia) yellow coloration. 3-Hydroxyanthranilic acid is an intermediate in the metabolism of tryptophan. It…

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  • Cholecystokinin aka pancreozymin notes

    History Structure Function Gastrointestinal Digestion Satiety The effects of CCK vary between individuals. For example, in rats , CCK administration significantly reduces hunger in adult males, but is slightly less effective in younger subjects, and even slightly less effective in females. The hunger-suppressive effects of CCK also are reduced in obese rats.  Fink H, Rex A, Voits M, Voigt…

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  • Rennet

    For the apple varieties, see Reinette Rennet is a complex set of enzymes produced in the stomachs of ruminant mammals. Chymosin, its key component, is a protease enzyme that curdles the casein in milk. In addition to chymosin, rennet contains other enzymes, such as pepsin and a lipase. Rennet has traditionally been used to separate milk into solid curds and liquid whey, used in the production of cheeses. Rennet from calves has become less common for this use, to the…

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  • Chymase and Chymosin – Rumored To Be Synonyms (and a little renin and rennin)

    Chymase Alternative name for chymosin [“chymase .” A Dictionary of Food and Nutrition. . Encyclopedia.com. 25 Aug. 2022 https://www.encyclopedia.com] Mast Cell Chymase and Tryptase and some MMPs Chymase and tryptase are packaged in secretory granules together with histamine and other mediators in mast cells, which are infiltrated in rheumatoid synovium. Chymase is a chymotrypsin-like proteinase with a broad spectrum of activity against ECM components such as type VI collagen7 and aggrecan. It…

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  • What Is Metalloproteinase?

    Metalloproteinase – the name alone screams “I’m here to ruin everything” – is a feral pack of enzymes armed with metal claws (zinc, mostly, because it’s the shiniest weapon in the elemental arsenal) that shred proteins like they’re auditioning for a slasher flick. These molecular psychopaths don’t just cut – they obliterate, turning the extracellular…

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  • What Are Plant Matrix Metalloproteinases?

    What Are Plant Matrix Metalloproteinases?

    Plant matrix metalloproteinases are metalloproteins and zinc enzymes found in plants. Matrix Metalloproteinase Matrix metalloproteinases (MMPs) are zinc endopeptidases, commonly called metzincins. MMP enzymes represent an ancient family of proteins with major similarities in genetic make-up that are present in a range of diverse organisms from unicellular bacteria to multicellular vertebrates and invertebrates. The superfamily is distinguished due to its motif consisting of three histidines bonded to…

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  • What are Matrix Metalloproteinases?

    The MMPs belong to a larger family of proteases known as the metzincin superfamily.[ Matrix Metalloproteinases: Its implications in cardiovascular disorders] Collectively, these enzymes are capable of degrading all kinds of extracellular matrix proteins, but also can process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands (such as the FAS ligand), and chemokine/cytokine inactivation.[Van…

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  • What Is Carnoy’s Solution?

    What Is Carnoy’s Solution?

    Carnoy’s solution is a fixative composed of 60% ethanol, 30% chloroform and 10% glacial acetic acid, 1 gram of ferric chloride.[1][2] Carnoy’s solution is also the name of a different fixation composed of ethanol and glacial acetic acid (3:1).[3][4][5] Hm..and here are some articles that come up on a search for Carnoy’s solution at Science Direct I haven’t read them all but this…

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  • Another reason not to feed pigeons – your food is poison?

    Another reason not to feed pigeons – your food is poison?

    I can’t tell you why except they showed up on a wiki search. Climate change has a negative effect on this bird, and reproductive performance decreases with increased temperatures. It is also particularly vulnerable to oil, and adults near oiled shores display symptoms of hepatocellular injury, where elevated levels of aspartate aminotransferase can be found in the liver. Otherwise,…

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  • Haldol: The Grim Reaper’s Sidekick

    Haloperidol, better known as Haldol, is not just a drug—it’s a cultural artifact of medicine’s darker corners. It has worn many hats: psychiatric savior, hospice workhorse, veterinary tranquilizer, and even a lurking specter in the shadowy world of death cocktails. This report dives deep into the multifaceted (and occasionally unsettling) life of Haldol, from its…

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  • Green synthesis of gold nanoparticles using aspartame and their catalytic activity for p-nitrophenol reduction

    Green synthesis of gold nanoparticles using aspartame and their catalytic activity for p-nitrophenol reduction

    Wu S, Yan S, Qi W, Huang R, Cui J, Su R, He Z. Green synthesis of gold nanoparticles using aspartame and their catalytic activity for p-nitrophenol reduction. Nanoscale Res Lett. 2015 May 8;10:213. doi: 10.1186/s11671-015-0910-7. PMID: 25991916; PMCID: PMC4431991. Abstract We demonstrated a facile and environmental-friendly approach to form gold nanoparticles through the reduction…

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  • Aspartame Notes

    Aspartame Notes

    NOTES ASPARTAME Under various names, aspartame is an ingredient in tens of thousands of consumables. some researchers suggest it is “by far” the most dangerous food additive. this is a collection of notes and articles concerning aspartame (in no particular order). HISTORY Aspartame was discovered in 1965 by James M. Schlatter, a chemist working for…

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