Tag: Breast

  • ADAM29: The Sperm’s Secret Weapon

    ADAM29 is the protein that’s bringing a whole new meaning to “family planning”! ADAM29 is like that mysterious friend who shows up at all the important life events but keeps their day job a secret. This protein is primarily expressed in the testis, making it a VIP member of the reproductive club45. Picture ADAM29 as…

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  • Osteopontin (OPN)

    Osteopontin (OPN), also known as bone /sialoprotein I (BSP-1 or BNSP), early T-lymphocyte activation (ETA-1), secreted phosphoprotein 1 (SPP1), 2ar and Rickettsia resistance (Ric), is a protein that in humans is encoded by the SPP1 gene (secreted phosphoprotein 1). The murine ortholog is Spp1. Osteopontin is a SIBLING (glycoprotein) that was first identified in 1986 in osteoblasts. The family of non-collagenous proteins known as SIBLING proteins, standing for small integrin-binding ligand, N-linked glycoprotein, are components of the extracellular matrix of bone and dentin. Evidence shows that these proteins play key…

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  • Gastrin-releasing peptide aka GRP and Pro-Gastrin-Releasing-Peptide aka Pro-GRP (and something called PreProGRP?)

    Gastrin-releasing peptide, also known as GRP, is a neuropeptide, a regulatory molecule that has been implicated in a number of physiological and pathophysiological processes. Most notably, GRP stimulates the release of gastrin from the G cells of the stomach. Function GRP is also involved in the biology of the circadian system, playing a role in the signaling of light to the master circadian oscillator in…

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