Tag: Cannabinoids
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Adenosine
Adenosine (symbol A) is an organic compound that occurs widely in nature in the form of diverse derivatives. The molecule consists of an adenine attached to a ribose via a β-N9–glycosidic bond. Adenosine is one of the four nucleoside building blocks of RNA (and its derivative deoxyadenosine is a building block of DNA), which are essential for all life. Its derivatives include the energy carriers adenosine mono-, di-, and triphosphate, also…
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AM404, aka N-arachidonoylphenolamine, is an active metabolite of paracetamolÂ
AM404, also known as N-arachidonoylphenolamine, is an active metabolite of paracetamol (acetaminophen), responsible for all or part of its analgesic action and anticonvulsant effects. Chemically, it is the amide formed from 4-aminophenol and arachidonic acid. Pharmacology It is established that AM404 increases concentrations of the endogenous cannabinoid anandamide within the synaptic cleft, contributing to its analgesic activity. This has been well characterised as involving endocannabinoid transporter inhibition, but the precise transporter responsible is yet to be…
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Dicoumarol (Moldy Sweet Clover) Toxicosis in a Group of Holstein Calves
Yamini B, Poppenga RH, Emmett BW, Judge LJ. Dicoumarol (Moldy Sweet Clover) Toxicosis in a Group of Holstein Calves. Journal of Veterinary Diagnostic Investigation. 1995;7(3):420-422. doi:10.1177/104063879500700328 References 1. Alstad AD, Casper HH, Johnson LJ: 1985, Vitamin K treatment of sweet clover poisoning in calves. J Am Vet Med Assoc 187:729–731. 2. Blakley BR: 1985, Moldy sweet clover (dicoumarol) poisoning in…
