Huntingtonās as Triadic Terrain Collapse: Sodium, SCNā», and CBP
Huntingtonās disease (HD) isnāt just a genetic script gone wrong, itās a terrain-wide collapse where sodium signaling and SCNā» redox shielding play hidden but pivotal roles. Letās decode the choreography: š§¬ I. Sodium Channels in Huntingtonās Terrain HD is marked by dysfunction in stri
š§¬ CBP in Alzheimerās Terrain: A Scribe Silenced by Sodium Collapse
š¹ 1. Presenilin Mutations ā CBP Suppression Presenilin loss doesnāt just build plaquesāit silences the terrainās scribe. š¹ 2. Amyloid & Tau ā Oxidative Siege on CBP CBP is the epigenetic quill. AĪ² and tau soak it in oxidative ink. š§ Sodium & SCNā»: The Forgotten Protecto
š§¬ CBP in 2025: Still the Terrainās Epigenetic Scribe
CBP (CREB-binding protein) remains highly relevant in 2025 across the very diseases weāve been decoding: Alzheimerās, Huntingtonās, FASD, and multiple cancers. In fact, its role has only deepened as research continues to expose its centrality in epigenetic regulation, DNA repair, and terrain-w
CBP-interacting proteins viewed through our sodium/SCNā» terrain lens
When viewed through our sodium/SCNā» terrain lens, this constellation of CBP-interacting proteins reveals a deep choreography of transcriptional integrity, redox buffering, and cellular sovereignty. Letās decode how each of these proteins connects to our framework: š§¬ CBP Interactors and Their