Tag: Constipation

  • HFE H63D & VO2 max

    SMOKE EM IF YOU GOT EM The HFE H63D is a single-nucleotide polymorphism in the HFE gene (c.187C>G, rs1799945), which results in the substitution of a histidine for an aspartic acid at amino acid position 63 of the HFE protein (p.His63Asp). HFE participates in the regulation of iron absorption. Homozygous H63D variant can occasionally be the cause of hemochromatosis. It is also…

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  • Enterochromaffin (EC) cells aka Kulchitsky cells

    Enterochromaffin (EC) cells (also known as Kulchitsky cells) are a type of enteroendocrine cell, and neuroendocrine cell. They reside alongside the epithelium lining the lumen of the digestive tract and play a crucial role in gastrointestinal regulation, particularly intestinal motility and secretion. They were discovered by Nikolai Kulchitsky. EC cells modulate neuron signalling in the enteric nervous system (ENS) via the secretion of the neurotransmitter serotonin and other peptides.…

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  • Haldol: The Grim Reaper’s Sidekick

    Haloperidol, better known as Haldol, is not just a drug—it’s a cultural artifact of medicine’s darker corners. It has worn many hats: psychiatric savior, hospice workhorse, veterinary tranquilizer, and even a lurking specter in the shadowy world of death cocktails. This report dives deep into the multifaceted (and occasionally unsettling) life of Haldol, from its…

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