Tag: CXCL12
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đź“„ The Ionic Collapse: Rethinking Salt as a Systemic Stabilizer in Modern Disease
Despite living in one of the most salt-rich nations on Earth, Americans—and much of the modern world—are experiencing a silent epidemic of salt-wasting syndromes: fatigue, infertility, immune collapse, clotting disorders, and early-onset cancer. This paradox is not due to a lack of salt in the environment, but to a systemic misallocation of salt across food,…
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🦴 Joint Disorders and the Ionic Collapse
Joint pain and degeneration are often framed as mechanical or autoimmune problems. But mounting evidence suggests that chronic joint disorders are also failures of immune coordination, vascular repair, and connective tissue signaling—all of which are governed by the PF4–CXCR4–CXCL12 axis and deeply influenced by ionic balance, especially sodium. 🔹 1. The PF4–CXCR4–CXCL12 Axis in Joint…
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🦵 Peripheral Artery Disease and the Ionic Collapse
Peripheral artery disease (PAD) is a form of atherosclerosis that affects the arteries of the limbs—most often the legs—leading to reduced blood flow, tissue ischemia, and in severe cases, ulcers, gangrene, or amputation. While traditionally viewed as a lipid-driven vascular disease, PAD is increasingly understood as a failure of vascular repair and immune coordination—precisely the…
Recent Posts
- 🧬 Disease Table with Low Sodium Connection
- 🧂 Sodium Reduction and Sodium Replacement: A History of Reformulation and Exploding Diseases, Including Many Diseases Unheard of Before Deadly Sodium Policies
- 🧂 The DEADLY 1500 mg Sodium Recommendation predates the WHO’s formal global sodium reduction push by nearly a decade (and it’s even worse than that)
- 🧬 What Is Beta-Glucuronidase?
- When Sugar Was Salt: Crystalline Confusion and the Covenant of Sweetness
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