Tag: Egg
-
ADAM36: The Reproductive Enigma
ADAM36 is the protein that’s playing a mysterious role in the world of reproduction! ADAM36 is like that enigmatic character in a novel who appears briefly but leaves a lasting impression. This protein is primarily expressed in the male reproductive system, particularly in the testis and epididymis. Picture ADAM36 as the secret agent of sperm…
-
ADAM26: The Sperm’s Surface Specialist
ADAM26 is the protein that’s making waves on the surface of sperm! ADAM26 is like that friend who’s always on the front lines, ensuring everything runs smoothly. This protein is specifically expressed on the surface of sperm, where it plays a crucial role in sperm-egg interactions. Picture ADAM26 as the matchmaker of the reproductive world.…
-
ADAM24: The Sperm’s Secret Weapon
ADAM24 is the protein that’s giving sperm their cutting edge! ADAM24, also known as Testase 1, is the James Bond of the sperm world. This plasma membrane-anchored protease is found exclusively on mature sperm, ready to spring into action when duty calls1. It’s believed to play a crucial role in sperm function during epididymal maturation…
-
ADAM34: the Bigfoot of the protein world
Prepare to be mystified by ADAM34, the protein that’s playing an elaborate game of hide-and-seek with scientists! ADAM34 is like that elusive celebrity who everyone’s heard of, but no one’s actually seen. This protein is shrouded in mystery, with researchers still debating its very existence in humans. It’s been spotted in mice, where it’s thought…
-
ADAM30: The Reproductive Rebel
ADAM30 is the protein that’s breaking all the rules in the reproductive playbook! ADAM30 is like that friend who shows up to a black-tie event in a Hawaiian shirt – it’s doing its own thing, and it doesn’t care who knows it. While most ADAM proteins are content with their roles in sperm production or…
-
ADAM1: The Wingman of the Fertilization World
Picture this: ADAM1 and ADAM2, arm in arm, strutting down the sperm surface like they own the place. They’re the power couple of the reproductive world, working together to make sure that when sperm meets egg, it’s love at first sight. ADAM1, also known as fertilin alpha, is the other half of the dynamic duo…
-
Tobacco-derived 4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice (decreases levels of pro-inflammatory cytokines; improves memory function; activates STAT3, Akt1, and CREB phosphorylation; and upregulates the mRNA levels of ORM2, GDNF, and C3) independent of the α7 nicotinic receptor
Rojas-Colón, L.A., Dash, P.K., Morales-Vías, F.A. et al. 4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice. J Neuroinflammation 18, 95 (2021). https://doi.org/10.1186/s12974-021-02136-9 LPS: Lipopolysaccharide “4R protects the hippocampus against inflammation and memory impairments triggered by LPS by lowering TNF-α and IL-1β levels and activation of the Akt1 and CREB signaling pathways. Astrocyte proteins involved in neuronal survival also…
-
Ovorubin
Ovorubin (PcOvo or PcPV1) is the most abundant perivitellin (>60 % total protein) of the perivitelline fluid from Pomacea canaliculata snail eggs. This glyco-lipo-caroteno protein complex is a approx. 300 kDa multimer of a combination of multiple copies of six different ~30 kDa subunits. Together with the other perivitellins from Pomacea canaliculata eggs, ovorubin serves a nutrient source for developing embryos, notably to the intermediate and late stages. Moreover, after hatching,…