The approximate biotin requirements of breeding hens have been established and the embryos examined for gross pathological symptoms and the approximate age at death are recorded. Cravens, W.W., W., & Sebesta, M.A. (1944). Effect of biotin deficiency on embryonic development in the domestic fowl.

Studies report that fetal exposure to paracetamol/acetaminophen by maternal consumption can interfere with male reproductive development. Moreover, recent biomonitoring data report widespread presence of paracetamol in German and Danish populations, suggesting exposure via secondary (nonpharmaceutic