AgrinĀ is a largeĀ chimeric proteoglycan, a heparan sulfate and chondroitin proteoglycan,Ā whose best-characterised role is in the development of theĀ neuromuscular junctionĀ duringĀ embryogenesis
Agrin was originally found in the electric organ of Tarpedo california and in the basal lamina at the neuromuscular junction as a protein that directs the aggregation of acetylcholine receptors (AChR) and acetylcholinesterase (AChE) at synaptic
Cadherin-1
Cadherin-1Ā orĀ Epithelial cadherin(E-cadherin), (not to be confused with theĀ APC/C activator protein CDH1) is aĀ proteinĀ that in humans is encoded by theĀ CDH1gene.[5]Ā Mutations are correlated withĀ gastric,Ā breast, colorectal, thyroid, and ovarian cancers. CDH1 has also been designated asĀ CD3
Hippo signaling pathway
The Hippo signaling pathway, also known as the Salvador-Warts-Hippo (SWH) pathway, is a signaling pathway that controls organ size in animals through the regulation of cell proliferation and apoptosis. The pathway takes its name from o
WW domain
TheĀ WW domain,[2]Ā (also known as theĀ rsp5-domain[3]Ā orĀ WWP repeatingĀ motif[4]) is a modularĀ protein domainĀ that mediates specific interactions with protein ligands. This domain is found in a number of unrelated signaling and structural proteins and may be repeated up to four times in some pr
YAP1Ā
YAP1Ā (yes-associated protein 1), also known asĀ YAPĀ orĀ YAP65, is a protein that acts as aĀ transcription coregulatorĀ that promotes transcription of genes involved inĀ cellular proliferationĀ and suppressingĀ apoptoticĀ genes. YAP1 is a component in theĀ hippo signaling pathwayĀ which regulates o