Hippo
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Agrin聽is a large聽chimeric proteoglycan, a heparan sulfate and chondroitin proteoglycan,聽whose best-characterised role is in the development of the聽neuromuscular junction聽during聽embryogenesis
Agrin was originally found in the electric organ of Tarpedo california and in the basal lamina at the neuromuscular junction as a protein that directs the aggregation of acetylcholine receptors (AChR) and acetylcholinesterase (AChE) at synaptic sites. Tetronarce californica also known as… Read more.
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Cadherin-1
Cadherin-1聽or聽Epithelial cadherin(E-cadherin), (not to be confused with the聽APC/C activator protein CDH1) is a聽protein聽that in humans is encoded by the聽CDH1gene.[5]聽Mutations are correlated with聽gastric,聽breast, colorectal, thyroid, and ovarian cancers. CDH1 has also… Read more.
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Hippo signaling pathway
The Hippo signaling pathway, also known as the Salvador-Warts-Hippo (SWH) pathway, is a signaling pathway that controls organ size in animals through the regulation of cell proliferation and apoptosis. The pathway takes its name from one of its key signaling components鈥攖he protein kinase Hippo (Hpo).… Read more.