Tag: HIV
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Graft-versus-host disease (GvHD) is divided into acute and chronic forms
Graft-versus-host disease (GvHD) is a syndrome, characterized by inflammation in different organs. GvHD is commonly associated with bone marrow transplants and stem cell transplants. Not to be confused with Host-versus-graft disease. White blood cells of the donor’s immune system which remain within the donated tissue (the graft) recognize the recipient (the host) as foreign (non-self). The white blood cells present within the…
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Maculopapular rash is seen in graft-versus-host disease (GVHD)
A maculopapular rash is a type of rash characterized by a flat, red area on the skin that is covered with small confluent bumps. It may only appear red in lighter-skinned people. The term “maculopapular” is a compound: macules are small, flat discolored spots on the surface of the skin; and papules are small, raised bumps. It is also described as erythematous, or red.…
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Reactive arthritis aka Reiter’s syndrome
Reportedly triggered by everything from food poisoning to bug bites to STDs to hormones (estrogen, relaxin) Mnemonic: Can't See, Can't Pee, Can't Climb a Tree
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Complement receptor type 2 (CR2)
Complement receptor type 2 (CR2), also known as complement C3d receptor, Epstein-Barr virus receptor, and CD21 (cluster of differentiation 21), is a protein that in humans is encoded by the CR2 gene. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells express CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation…
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Complement receptor type 1 (CR1)
Complement receptor type 1 (CR1) also known as C3b/C4b receptor or CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the CR1 gene. This gene is a member of the regulators of complement activation (RCA) family and is located in the ‘cluster RCA’ region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, hyalocytes, and splenic follicular dendritic…
