Tag: Hormones
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Chalone Rangers: The Tissue-Specific Mitotic Inhibitors You Never Knew You Needed
Chalones are the unsung heroes of cellular crowd control. These tissue-specific, water-soluble substances are like the bouncers of your body, standing at the gates of mitosis with their arms crossed, saying, âNot tonight, buddy.â Theyâre the biochemical equivalent of that one friend who knows when to call it a night before things get out of…
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Autacoids Unleashed: The Self-Made, Self-Destructive Hormones You Didnât Know You Needed
What Are Autacoids? Autacoids (or autocoids) are the bodyâs DIY hormonesâlocally produced, short-lived biochemical messengers that scream, âI got this!â before promptly fading into oblivion. The term comes from the Greek autos (self) and acos (relief or drug), which is ironic because theyâre basically the overachieving interns of the body: they do all the work locally, get no credit,…
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Snake Venom: The Hormone Hijacker đ
Imagine a villainous mastermind that can infiltrate your body’s hormonal headquarters, manipulating the delicate balance of estrogen and other hormones. Welcome to the world of snake venom, where the stakes are high and the effects are unpredictable. Estrogen’s Uninvited Guest: When Snake Venom Crashes the Hormone Hoedown Prepare for the most bizarre gatecrasher at the…
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Eraso Y. Biotypology, endocrinology, and sterilization: the practice of eugenics in the treatment of Argentinian women during the 1930s. Bull Hist Med. 2007 Winter;81(4):793-822. doi: 10.1353/bhm.2007.0130. PMID: 18084107; PMCID: PMC2629848.
SUMMARYThis article looks at medical approaches to womenâs fertility in Argentina in the 1930s and explores the ways in which eugenics encouraged the reproduction of the fit and attempted to avoid the reproduction of the unfit. The analysis concentrates on three main aspects: biotypology (the scientific classification of bodies), endocrine therapy, and sterilization. The article…
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the hormone hustle
We’re about to embark on a time-traveling, mind-bending journey through the evolution of normalization, biopolitics, and the wild world of hormones. From Foucault’s philosophical bombshells to Nicola Pende’s hormone-fueled science experiments, this is a story that will leave you questioning everything you thought you knew about “normal.” Act I: The Birth of Biopower (18th Century) Picture…
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Beccalossi C. Sexology, sexual development, and hormone treatments in Southern Europe and Latin America, c.1920-40. Hist Human Sci. 2023 Dec;36(5):94-121. doi: 10.1177/09526951231213028. Epub 2023 Dec 6. PMID: 38077463; PMCID: PMC10700059.
AbstractDisplacing the physiological model that had held sway in 19th-century medical thinking, early 20th-century medical scientists working on hormones promoted a new understanding of the body, psychological reactions, and the sexual instinct, arguing that each were fundamentally malleable. Hormones came to be understood as the chemical messengers that regulated an individual’s growth and sexual development,…
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Beccalossi C. Italian sexology, Nicola Pende’s biotypology and hormone treatments in the 1920s. Hist Med Sante. 2017 Winter;12:73-97. doi: 10.4000/hms.1173. Epub 2018 May 28. PMID: 31501760; PMCID: PMC6733708.
AbstractThis article analyses a selection of Nicola Pendeâs studies from the 1920s on âendocrinological abnormalitiesâ associated with impotence, a lack of virility in men, a lack of femininity in women, and homosexuality. By analysing endocrinological sexual theories and treatments, it aims to illustrate the ways in which hormone research pioneered an innovative approach to the…
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BECCALOSSI C. Optimizing and normalizing the population through hormone therapies in Italian science, c.1926â1950. The British Journal for the History of Science. 2020;53(1):67-88. doi:10.1017/S0007087419000906
Abstract This essay explores how hormone treatments were used to optimize and normalize individuals under Italian Fascism. It does so by taking the activities of the Biotypological Orthogenetic Institute â an Italian eugenics and endocrinological centre founded by Nicola Pende in 1926 â as the prime example of a version of eugenics, biotypology, which was…
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the ULTIMATE BUGGY BASS DROP
Oh snap, buckle up buttercup, ’cause we’re about to dive deep into the wildest rave this side of the exoskeleton! đđ Imagine, if you will, a microscopic mosh pit where insects are gettin’ jiggy with it on a molecular level. It’s not your average hormone hoedown, oh no â this is the ULTIMATE BUGGY BASS…
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Buggy Love Potion: The Science of Insect Sex Hormones
Listen up, you sexy six-legged sirens and alluring arthropods! đđ Get ready to have your mind blown and your exoskeleton rocked. Insect sex hormones: They’re real, they’re spectacular, and they’re changing the game of love in the miniature world! From ecdysone’s double life to gonadotropins’ matchmaking skills, these hormones are the unsung heroes of insect…
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Brain-derived neurotrophic factor (BDNF) aka abrineurin
Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4/NT-5. Neurotrophic factors are found in the brain and the periphery. BDNF was first isolated from a pig brain in 1982 by Yves-Alain Barde and Hans Thoenen. BDNF…
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Neurotrophin-3 and Neurotrophin-4
Neurotrophin-4 (NT-4), also known as neurotrophin-5 (NT-5), is a protein that in humans is encoded by the NTF4 gene. It is a neurotrophic factor that signals predominantly through the TrkB receptor tyrosine kinase. NT-4 was first discovered and isolated from xenopus and viper in the year 1991 by Finn Hallbook et.al Neurotrophin-3 is a protein that in humans is encoded by the NTF3 gene. The protein encoded by this gene, NT-3, is a neurotrophic factor in the NGF (Nerve…
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The PVN Powerhouse: How the Paraventricular Nucleus Rules Hormone Secretion
Hold onto your hypothalamus, folks! We’re about to dive into the wild world of the Paraventricular Nucleus (PVN), where tiny cells pack a mighty hormonal punch! Picture this: deep in the brain’s control center, the hypothalamus, sits the PVN – a cluster of cells that’s like the body’s own hormone factory. But we’re not talking…
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The transforming growth factor beta receptors
a family of serine/threonine kinase receptors involved in TGF beta signaling pathway
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The adrenal medulla is the principal site of the conversion of the amino acid tyrosine into the catecholamines; epinephrine, norepinephrine, and dopamine
The adrenal medulla (Latin: medulla glandulae suprarenalis) is part of the adrenal gland. It is located at the center of the gland, being surrounded by the adrenal cortex. It is the innermost part of the adrenal gland, consisting of chromaffin cells that secrete catecholamines, including epinephrine (adrenaline), norepinephrine (noradrenaline), and a small amount of dopamine, in response to stimulation by sympathetic preganglionic neurons. Structure The adrenal medulla consists of irregularly shaped cells…
