Immunodeficiency – Mere Moonshine

January 16, 2024

4, DNA, Dumbbells, Embryology, Hamster, Immunology, Serine/Threonine, Tertiary

Structure of DNA repair protein XRCC4 aka X-ray repair cross-complementing protein 4

XRCC4 protein is a TETRAMER that resembles the shape of a DUMBBELL containing two globular ends separated by a long, thin stalk. The tetramer is composed of two dimers, and each dimer is made up of two similar subunits. The first subunit (L) contains amino acid residues 1 – 203 and has a longer

July 20, 2023

Heparin, Hormones, Immunology, Metals, Reproduction

The transforming growth factor beta receptors

a family of serine/threonine kinase receptors involved in TGF beta signaling pathway

July 10, 2023

Complement, Inborn Errors, Lymphoid and compliment disorders causing immunodeficiency, Seeing Red, Who's Who

Adenosine deaminase deficiency (ADA deficiency) was discovered in 1972 and recognized as the first immunodeficiency disorder

Adenosine deaminase deficiency (ADA deficiency) is a metabolic disorder that causes immunodeficiency. It is caused by mutations in the ADA gene. It accounts for about 10–15% of all cases of autosomal recessive forms of severe combined immunodeficiency (SCID) among non-inbred populations

July 10, 2023

Hormones, Neurotransmitters

Adenosine

Adenosine (symbol A) is an organic compound that occurs widely in nature in the form of diverse derivatives. The molecule consists of an adenine attached to a ribose via a β-N9–glycosidic bond. Adenosine is one of the four nucleoside building