Tag: Infertility
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Sodium and thiocyanate suppression causes infertility (and most every other health problem)
Sodium is absolutely essential to life, reproduction, and systemic coherence. Briefly: Without sodium, life collapses into incoherence. It’s not seasoning—it’s signal. But you may not know the same is true for thiocyanate, a kind of mammal marker required for life and proper functioning and reproduction. Sodium deficiency represses thiocyanate. The best workaround for humans may…
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salt deficiency may mimic other conditions
Here’s a concise, evidence-informed breakdown showing how acute or chronic sodium deficiency or mismanagement (restriction, wasting, or inability to retain) may mimic, exacerbate, or parallel mechanisms seen in these conditions. Each bullet links sodium to key dysfunctions: Parkinson’s Disease COVID Complications Vaccine Reactions Alzheimer’s Disease Autoimmune Conditions Fatigue & Chronic Exhaustion Heart Problems & Arrhythmias…
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ADAM29: The Sperm’s Secret Weapon
ADAM29 is the protein that’s bringing a whole new meaning to “family planning”! ADAM29 is like that mysterious friend who shows up at all the important life events but keeps their day job a secret. This protein is primarily expressed in the testis, making it a VIP member of the reproductive club45. Picture ADAM29 as…
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HFE H63D & VO2 max
SMOKE EM IF YOU GOT EM The HFE H63D is a single-nucleotide polymorphism in the HFE gene (c.187C>G, rs1799945), which results in the substitution of a histidine for an aspartic acid at amino acid position 63 of the HFE protein (p.His63Asp). HFE participates in the regulation of iron absorption. Homozygous H63D variant can occasionally be the cause of hemochromatosis. It is also…
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Freemartin
A freemartin or free-martin (sometimes martin heifer) is an infertile female cattle with masculinized behavior and non-functioning ovaries.[1] Phenotypically, the animal appears female, but various aspects of female reproductive development are altered due to acquisition of anti-Müllerian hormone from the male twin.[2] Genetically, the animal is chimeric: karyotypy of a sample of cells shows XX/XY chromosomes. The animal originates as a female (XX), but acquires the male (XY) component in utero by exchange of…
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Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility
Studies report that fetal exposure to paracetamol/acetaminophen by maternal consumption can interfere with male reproductive development. Moreover, recent biomonitoring data report widespread presence of paracetamol in German and Danish populations, suggesting exposure via secondary (nonpharmaceutical) sources, such as metabolic conversion from the ubiquitous industrial compound aniline. In this study, we investigated the extent to which…
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Prolactin (PRL)
In mammals, prolactin is associated with milk production; in fish it is thought to be related to the control of water and salt balance. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. It has important cell cycle-related functions as a growth-, differentiating- and anti-apoptotic factor. As a growth factor,…
