HFE H63D & VO2Â max
SMOKE EM IF YOU GOT EM The HFE H63D is a single-nucleotide polymorphism in the HFE gene (c.187C>G, rs1799945), which results in the substitution of a histidine for an aspartic acid at amino acid position 63 of the HFE protein (p.His63Asp). HFE participates in the regulation of iron absorption.
Transferrin binding and PH
Transferrin binding to transferrin receptors reduces its affinity for iron. Two pathways can occur once endocytosedâdegradation or recycling pathways. The degradation pathway is where the dissociation of ferric ions from transferrin occurs from an early and late endosome. Iron can now be utilized
Thermolysin – The Tiny Terminator of Plasma Proteins!
Both thermolysin and snake venom metalloproteinases (SVMPs) share a similar mechanism of action, utilizing zinc ions to hydrolyze peptide bonds in proteins
DMT1 aka DCT1 and NRAMP2
Natural resistance-associated macrophage protein 2 (NRAMP 2), also known as divalent metal transporter 1 (DMT1) and divalent cation transporter 1 (DCT1), is a protein that in humans is encoded by the SLC11A2 (solute carrier family 11, member 2)
Ovotransferrin aka conalbumin
Ovotransferrin (conalbumin) is a glycoprotein of egg white albumen. Egg white albumen is composed of multiple proteins, of which ovotransferrin is the most heat reliable. It has a molecular weight of 76,000 daltons and contains about 700 amino acids. Ovotransferrin makes up approximately 13
Laterite
Laterite is a soil type rich in iron and aluminium and is commonly considered to have formed in hot and wet tropical areas. Nearly all laterites are of rusty-red coloration, because of high iron oxide content. They develop by intensive and prolonged weathering of the underlying parent rock
Saprolite
Saprolite is a chemically weathered rock. Saprolites form in the lower zones of soil profiles and represent deep weathering of the bedrock surface. In most outcrops, its color comes from ferric compounds. Deeply weathered profiles are widespread on t
Cupronickel or copper-nickel (CuNi) is an alloy of copper that contains nickel and strengthening elements, such as iron and manganese
The copper content typically varies from 60 to 90 percent. (Monel is a nickel-copper alloy that contains a minimum of 52 percent nickel.) Despite its high copper content, cupronickel is silver in colour. Cupronickel is highly resistant to corrosion by salt water, and is therefore used for piping,
Transferrins
Transferrins are not limited to only binding to iron but also to different metal ions.
Hephaestin, first identified in 1999 is homologous with ceruloplasmin
Named after Hephaestus, the Greek god of metal working
Ceruloplasmin carries more than 95% of the total copper in healthy human plasma and in addition plays a role in iron metabolism. It was first described in 1948.
Ceruloplasmin (or caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. Ceruloplasmin is the major copper-carrying protein in the blood, and in addition plays a role in iron metabolism. It was first described in 1948. Another protein, hephaestin, is noted for it
Supergene (geology) and something called gossan cap
In ore deposit geology, supergene processes or enrichment are those that occur relatively near the surface as opposed to deep hypogene processes. Supergene processes include the predominance of meteoric water circulation (i.e. water derived from prec