Tag: Magnesium
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Saprolite
Saprolite is a chemically weathered rock. Saprolites form in the lower zones of soil profiles and represent deep weathering of the bedrock surface. In most outcrops, its color comes from ferric compounds. Deeply weathered profiles are widespread on the continental landmasses between latitudes 35°N and 35°S. Conditions for the formation of deeply weathered regolith include a topographically moderate relief flat enough to prevent erosion and to allow leaching of the products of chemical weathering. A second…
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Catecholamine (CA)
A catecholamine (abbreviated CA) is a monoamine neurotransmitter, an organic compound that has a catechol (benzene with two hydroxyl side groups next to each other) and a side-chain amine. Fitzgerald, P. A. (2011). “Chapter 11. Adrenal Medulla and Paraganglia”. In Gardner, D. G.; Shoback, D. (eds.). Greenspan’s Basic & Clinical Endocrinology (9th ed.). New York: McGraw-Hill. Retrieved October 26, 2011. Catechol, not to be confused with Catechin which is also sometimes called catechol, can be either…
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Magnesium Deficiency Causes a Reversible, Metabolic, Diastolic Cardiomyopathy (2021)
Background Dietary Mg intake is associated with a decreased risk of developing heart failure, whereas low circulating Mg level is associated with increased cardiovascular mortality. We investigated whether Mg deficiency alone could cause cardiomyopathy. Methods and Results C57BL/6J mice were fed with a low Mg (low-Mg, 15-30 mg/kg Mg) or a normal Mg (nl-Mg, 600…
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The hyperventilation syndrome: a neurosis or a manifestation of magnesium imbalance? (1985)
It has been proven with clinical, psychological and electromyographic tests that the hyperventilation (HV) syndrome cannot be separated from so-called genuine tetany. Tetanic patients with and without HV are characterized by a significant hypocalcemia; but a significant hypomagnesemia is exclusively found in tetanic patients with HV attacks. Possible pathogenic mechanisms are discussed which may explain…
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Latent tetany and anxiety, marginal magnesium deficit, and normocalcemia (1975)
The identification of marginal magnesium deficit, such as we have detected in a patient with anxiety, depression, and psychomatic complaints, is a difficult diagnostic problem. Electromyography of a limb, rendered acutely ischemic either just before or after hyperventilation, can elicit latent tetany in this condition, as well as in calcium deficiency. We have demonstrated iterative…
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Hypomagnesemic tetany of ruminants (1988)
Hypomagnesemic tetany of ruminants is a noninfectious metabolic disorder that occurs in a wide range of nutritional and management conditions. This article considers its etiology and pathogenesis, clinical signs, clinical pathology and lesions, diagnosis, clinical management, prevention, and control. Smith RA, Edwards WC. Hypomagnesemic tetany of ruminants. Vet Clin North Am Food Anim Pract. 1988…
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The magnesium-deficiency tetany syndrome in man (1960)
Magnesium is second only to potassium in abundance as an intracellular cation. The whole body of a human adult contains nearly 25 gm. The numerous important biochemical reactions dependent upon the presence of this metal have been discussed elsewhere. Magnesium is an essential nutrient for animals and plants, suggesting that a dietary inadequacy of this ion might…
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Studies on the nutritional basis of abnormal behavior in albino rats; the effect of pyridoxine deficiency upon sound-induced magnesium tetany (1945)
After a magnesium deficient diet for 5 to 8 days, young rats showed vasodilatation, hyperirritability, and latent tetany. Brief exposures to the sound of a resonated buzzer elicited severe tonic-clonic convulsions. When such a diet was continued for 10 to 23 days, sensitivity increased with death resulting from spontaneous or induced seizures. In a similar…
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Phosphopyruvate hydratase, aka enolase, is a metalloenzyme that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis
Phosphopyruvate hydratase, usually known as enolase, is a metalloenzyme (EC 4.2.1.11) that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis. The chemical reaction is:2-phospho-D-glycerate ⇌ phosphoenolpyruvate + H2O Phosphopyruvate hydratase belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme is 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming). The reaction is reversible, depending on environmental concentrations of…