Tag: Malnutrition
-
Hypomagnesemic tetany of ruminants (1988)
Hypomagnesemic tetany of ruminants is a noninfectious metabolic disorder that occurs in a wide range of nutritional and management conditions. This article considers its etiology and pathogenesis, clinical signs, clinical pathology and lesions, diagnosis, clinical management, prevention, and control. Smith RA, Edwards WC. Hypomagnesemic tetany of ruminants. Vet Clin North Am Food Anim Pract. 1988…
-
Studies on the nutritional basis of abnormal behavior in albino rats; the effect of pyridoxine deficiency upon sound-induced magnesium tetany (1945)
After a magnesium deficient diet for 5 to 8 days, young rats showed vasodilatation, hyperirritability, and latent tetany. Brief exposures to the sound of a resonated buzzer elicited severe tonic-clonic convulsions. When such a diet was continued for 10 to 23 days, sensitivity increased with death resulting from spontaneous or induced seizures. In a similar…
-
Experts warn of fatty liver disease ‘epidemic’ in young people
In Bristol University‘s study Children of the 90s, 2.5% of 4,000 people born in 1991 and 1992 were found by ultrasound scanning at the age of 18 to have non-alcoholic fatty liver disease; five years later transient elastography (fibroscan) found over 20% to have the fatty deposits on the liver of steatosis, indicating non-alcoholic fatty liver disease; half of those…
-
Lytico-bodig disease, Guam disease, or amyotrophic lateral sclerosis-parkinsonism-dementia (ALS-PDC) is a neurodegenerative disease or all of them
Lytico-bodig (also Lytigo-bodig) disease, Guam disease, or amyotrophic lateral sclerosis-parkinsonism-dementia (ALS-PDC) is a neurodegenerative disease of uncertain etiology endemic to the Chamorro people of the island of Guam in Micronesia. Lytigo and bodig are Chamorro language words for two different manifestations of the same condition. ALS-PDC, a term coined by Asao Hirano and colleagues in 1961, reflects its resemblance to amyotrophic lateral sclerosis (ALS), Parkinson’s disease, and Alzheimer’s disease. First reports of the disease surfaced in three death certificates on Guam in 1904 which made…
-
Malnutrition may play a role in Tropical ataxic neuropathy (TAN) aka Strachan-Scott Syndrome and prisoners of war neuropathy
Tropical ataxic neuropathy (TAN, also known as Strachan-Scott Syndrome and prisoners of war neuropathy) is a disease or category of diseases that commonly causes disability and increases mortality. The causes of TAN are not understood; there is no generally accepted treatment, and the reported outcomes are inconsistent. The disease affects poor tropical populations; there are no good statistics on how…
-
Cause and Prevention of Konzo
The character of the neurological injury is not clear. The disease onset is associated with high intake of cyanide from a diet of mostly bitter cassava, which is low in protein, particularly sulfur amino acids. These are essential for the detoxification in the body of cyanide to thiocyanate, which is removed in the urine. A…
-
Signs and symptoms of Konzo
The onset of paralysis (spastic paraparesis) is sudden and symmetrical and affects the legs more than the arms. The resulting disability is permanent but does not progress. Typically, a patient is standing and walking on the balls of the feet with rigid legs and often with ankle clonus. Initially, most patients experience generalized weakness during the first…
-
Differential diagnoses for Konzo are lathyrism and paraparesis apparently caused by geographical location or bad genes…go figure
The clinical symptoms are strikingly similar to those of lathyrism and also similar to tropical spastic paraparesis and hereditary spastic paraparesis, only that the latter two disorders have a slow onset. Konzo is distinct from polio which is a flaccid paralysis and most often affects a person asymmetrically.[citation needed] Konzo is one of several tropical neuropathies. A distinct myeloneuropathy also associated to cyanogen intake from cassava is tropical ataxic…
-
Konzo is an epidemic paralytic disease reportedly from simultaneous malnutrition and high dietary cyanide intake
Konzo is an epidemic paralytic disease occurring among hunger-stricken rural populations in Africa where a diet dominated by insufficiently processed cassava results in simultaneous malnutrition and high dietary cyanide intake. Konzo was first described by Giovanni Trolli in 1938 who compiled the observations from eight doctors working in the Kwango area of the Belgian Congo (now Democratic Republic of the Congo). “Konzo” means “tied legs” in…
-
The Poisonous Pulse of Vapniarka: Grasspea, Lathyrism, and the Holocaust’s Forgotten Horror
During the Second World War, amidst the atrocities of the Holocaust, a little-remembered but harrowing chapter unfolded in the Vapniarka concentration camp in Transnistria. Here, under the command of Colonel Ioan Murgescu, over 1,000 Jewish detainees were subjected to a cruel experiment in survival: they were fed almost exclusively on Lathyrus sativus, or grass pea, a…
-
Lysine Tyrosylquinone (LTQ)
LTQ does not have a wikipedia page so I will check elsewhere. In the meantime, I found another reason to just say no to beans – osteolathyrism aka odoratism, which is a form of the disease Lathyrism. Wikipedia says: The disease results from the ingestion of Lathyrus odoratus seeds (sweet peas) from the family Fabaceae (legumes). The toxin found in the sweet peas is…
-
Human placental lactogen (hPL)
Human placental lactogen (hPL), also called human chorionic somatomammotropin (HCS), is a polypeptideplacental hormone, the human form of placental lactogen (chorionic somatomammotropin). Its structure and function are similar to those of human growth hormone. It modifies the metabolic state of the mother during pregnancy to facilitate the energy supply of the fetus. hPL has anti-insulin properties. hPL is a hormone secreted by the syncytiotrophoblast during pregnancy. Like human growth hormone, hPL…
-
Oxalyldiaminopropionic acid (ODAP) is a structural analogue of the neurotransmitter glutamate found in the grass pea Lathyrus sativus
Oxalyldiaminopropionic acid (ODAP) is a structural analogue of the neurotransmitter glutamate found in the grass pea Lathyrus sativus. It is the neurotoxin responsible for the motor neuron degeneration syndrome lathyrism. Woldeamanuel, Yohannes W.; Hassan, Anhar; Zenebe, Guta (2011-11-12). “Neurolathyrism: two Ethiopian case reports and review of the literature”. Journal of Neurology. 259 (7): 1263–1268. doi:10.1007/s00415-011-6306-4. ISSN 0340-5354. PMID 22081101. S2CID 27543906. Sources ODAP is found in the seeds of the legume L. sativus, a grass pea…
-
The sweet pea is a flowering plant in the genus Lathyrus in the family Fabaceae (legumes) 🧪☣️☠️⚗️🤢
The sweet pea, Lathyrus odoratus, is a flowering plant in the genus Lathyrus in the family Fabaceae (legumes), native to Sicily, southern Italy and the Aegean Islands. It is an annual climbing plant, growing to a height of 1–2 metres (3 ft 3 in – 6 ft 7 in), where suitable support is available. The leaves are pinnate with two leaflets and a terminal tendril, which twines around supporting plants and structures, helping the sweet pea to climb. In…
