Tag: metalloproteins

  • The molecular mayhem of immunogens, haptens, carriers and adjuvants

    The molecular mayhem of immunogens, haptens, carriers and adjuvants

    First up, the immunogen: the molecular maestro of the immune system, orchestrating a symphony of B-cells and T-cells like a conductor with a grudge. These substances don’t just knock politely on the immune system’s door—they kick it down with the force of a battering ram. Immunogens are a subset of antigens (because “antibody-generating” wasn’t obvious enough)…

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  • Phosphopyruvate hydratase, aka enolase, is a metalloenzyme that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis

    Phosphopyruvate hydratase, aka enolase, is a metalloenzyme that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis

    Phosphopyruvate hydratase, usually known as enolase, is a metalloenzyme (EC 4.2.1.11) that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis. The chemical reaction is:2-phospho-D-glycerate ⇌ phosphoenolpyruvate + H2O Phosphopyruvate hydratase belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme is 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming). The reaction is reversible, depending on environmental concentrations of…

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  • What Is Metalloproteinase?

    Metalloproteinase – the name alone screams “I’m here to ruin everything” – is a feral pack of enzymes armed with metal claws (zinc, mostly, because it’s the shiniest weapon in the elemental arsenal) that shred proteins like they’re auditioning for a slasher flick. These molecular psychopaths don’t just cut – they obliterate, turning the extracellular…

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  • What Are Plant Matrix Metalloproteinases?

    What Are Plant Matrix Metalloproteinases?

    Plant matrix metalloproteinases are metalloproteins and zinc enzymes found in plants. Matrix Metalloproteinase Matrix metalloproteinases (MMPs) are zinc endopeptidases, commonly called metzincins. MMP enzymes represent an ancient family of proteins with major similarities in genetic make-up that are present in a range of diverse organisms from unicellular bacteria to multicellular vertebrates and invertebrates. The superfamily is distinguished due to its motif consisting of three histidines bonded to…

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