Paracetamol is an aniline derivative with a sketchy date of birth (and a very sketchy rebirth)
Paracetamol was first made in 1877…or possibly 1852. Some reports state that Cahn & Hepp or a French chemist called Charles Gerhardt first synthesized paracetamol in 1852. AcetanilideĀ was the firstĀ anilineĀ derivative serendipitously found to possess analgesic as well asĀ antipyreticĀ pr
Paracetamol is extremely toxic to cats, which lack the necessaryĀ UGT1A6Ā enzyme to detoxify it
Paracetamol is extremely toxic to cats, which lack the necessaryĀ UGT1A6Ā enzyme to detoxify it. Initial symptoms include vomiting, salivation, and discoloration of the tongue and gums. Unlike an overdose in humans, liver damage is rarely the cause of death; instead,Ā methemoglobinĀ formation and th
What Is Nitrophenol? (besides something mentioned in āScientific Opinion on the reāevaluation of aspartame as a food additiveā)
Nitrophenols are compounds of the formula HOC6H5āx(NO2)x. The conjugate bases are called nitrophenolates. Nitrophenols are more acidic than phenol itself. Wikipedia Mono-nitrophenols with the formula HOC6H4NO2. Three isomeric nitrophenols exist: o-Nitrophenol (2-