Tag: NITROPHENOL

  • 4-Aminophenol – what a molecule!

    This is a humble organic compound with the formulaĀ H2NC6H4OH, but don’t let its unassuming structure fool you. This is not just any crystalline powder; this is a chemical that moonlights as a pharmaceutical ingredient, a hair dye precursor, and—wait for it—a black-and-white film developer. If molecules had rĆ©sumĆ©s, 4-Aminophenol’s would read like someone who’s worked…

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  • Paracetamol is an aniline derivative with a sketchy date of birth (and a very sketchy rebirth)

    Paracetamol was first made in 1877…or possibly 1852. Some reports state that Cahn & Hepp or a French chemist called Charles Gerhardt first synthesized paracetamol in 1852. AcetanilideĀ was the firstĀ anilineĀ derivative serendipitously found to possess analgesic as well asĀ antipyreticĀ properties, and was quickly introduced into medical practice under the name ofĀ AntifebrinĀ by Cahn & Hepp in 1886. But…

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  • Hapten

    In immunology, haptens are small molecules that elicit an immune response only when attached to a large carrier such as a protein; the carrier may be one that also does not elicit an immune response by itself (in general, only large molecules, infectious agents, or insoluble foreign matter can elicit an immune response in the body). Once the body has generated antibodies to a hapten-carrier adduct, the small-molecule hapten may…

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  • What Is Nitrophenol? (besides something mentioned in ā€˜Scientific Opinion on the re‐evaluation of aspartame as a food additive’)

    What Is Nitrophenol? (besides something mentioned in ā€˜Scientific Opinion on the re‐evaluation of aspartame as a food additive’)

    Nitrophenols are compounds of the formula HOC6H5āˆ’x(NO2)x. The conjugate bases are called nitrophenolates. Nitrophenols are more acidic than phenol itself. Wikipedia Mono-nitrophenols with the formula HOC6H4NO2. Three isomeric nitrophenols exist: o-Nitrophenol (2-nitrophenol; OH and NO2 groups are neighboring; CAS number: 88-75-5), a yellow crystalline solid (m.p. 46 °C). m-Nitrophenol (3-nitrophenol, CAS number: 554-84-7), a yellow solid (m.p. 97 °C) and precursor to the…

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  • 4-Nitrophenol mentioned in ‘Scientific Opinion on the re‐evaluation of aspartame (E 951) as a food additive’ (2013)

    4-Nitrophenol mentioned in ‘Scientific Opinion on the re‐evaluation of aspartame (E 951) as a food additive’ (2013)

    3.2.6.2. Studies on the effect of aspartame administration on xenobiotic metabolising enzymesAn early study (E15, 1972) indicated that the oral administration of aspartame to male Charles River rats (2000-4000 mg/kg) for four days had no acute effect on hepatic cytochrome P450 (CYP)-mediated xenobiotic metabolism, as measured as aminopyrine N-demethylation, p-nitroanisole Ndemethylation, hexobarbital sleeping time or…

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  • Green synthesis of gold nanoparticles using aspartame and their catalytic activity for p-nitrophenol reduction

    Green synthesis of gold nanoparticles using aspartame and their catalytic activity for p-nitrophenol reduction

    Wu S, Yan S, Qi W, Huang R, Cui J, Su R, He Z. Green synthesis of gold nanoparticles using aspartame and their catalytic activity for p-nitrophenol reduction. Nanoscale Res Lett. 2015 May 8;10:213. doi: 10.1186/s11671-015-0910-7. PMID: 25991916; PMCID: PMC4431991. Abstract We demonstrated a facile and environmental-friendly approach to form gold nanoparticles through the reduction…

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  • Aspartame Notes

    Aspartame Notes

    NOTES ASPARTAME Under various names, aspartame is an ingredient in tens of thousands of consumables. some researchers suggest it is “by far” the most dangerous food additive. this is a collection of notes and articles concerning aspartame (in no particular order). HISTORY Aspartame was discovered in 1965 by James M. Schlatter, a chemist working for…

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