The first hepatitis B vaccine was approved in the United States in 1981. A recombinant version came to market in 1986. Both versions were developed by Maurice Hilleman and his team. (a history of hepatitis B vaccine)
Preliminary work In 1963, the American physician/geneticist Baruch Blumberg, working at the Fox Chase Cancer Center, discovered what he called the “Australia Antigen” (HBsAg) in the serum of an Australian Aboriginal person. In 1968, this protein was found to be part of the virus that
Physiology of the gastrointestinal system
of the intestinal UPPER GI TRACT
The lactating birds and the bees (gastrin, pepsin, etc)
Crop milk is a secretion from the lining of the crop of parent birds that is regurgitated to young birds. It is found among all pigeons and doves where it is referred to as pigeon milk. An analog to crop milk is also secreted from the esophagus of flamingos and the male emperor penguin. D
Pepsinogens are mainly grouped in 5 different groups based on their primary structure
1. Pepsinogen A (also called pepsinogen I) 2. Pepsinogen B 3. Progastricsin (also called pepsinogen II and pepsinogen C) 4. Prochymosin (also called prorennin) 5. Pepsinogen F (also called pregnancy-associated glycoprotein).
Nepenthesin (and the carnivorous plants it comes from)
Nepenthesin (also spelled nepenthacin or nepenthasin) is an aspartic protease of plant origin that has so far been identified in the pitcher secretions of Nepenthes and in the leaves of Drosera peltata. Discovery In the late 19th century, Sydney Howard Vines showed that the pitcher flui
Chymase and Chymosin – Rumored To Be Synonyms (and a little renin and rennin)
Chymase Alternative name for chymosin [“chymase .” A Dictionary of Food and Nutrition. . Encyclopedia.com. 25 Aug. 2022 https://www.encyclopedia.com] Mast Cell Chymase and Tryptase and some MMPs Chymase and tryptase are packaged in secret
What Is Metalloproteinase?
Metalloproteinase – the name alone screams âIâm here to ruin everythingâ – is a feral pack of enzymes armed with metal claws (zinc, mostly, because itâs the shiniest weapon in the elemental arsenal) that shred proteins like theyâre auditioning for a slasher flick. These molecul