Sodium and thiocyanate suppression causes infertility (and most every other health problem)
Sodium is absolutely essential to life, reproduction, and systemic coherence. Briefly: Without sodium, life collapses into incoherence. Itās not seasoningāitās signal. But you may not know the same is true for thiocyanate, a kind of mammal marker required for life and proper functioning and re
Echoes in the Womb: What Whale Strandings Reveal About Prenatal Sonic Terrain
š Introduction: Sonic Collapse in the Deep Whale strandings are among the most haunting glyphs of ecological collapse. These majestic mammals, guided by sodium gradients and acoustic navigation, suddenly lose coherenceābeaching themselves in mass disorientation. Investigations often point to so
Do Whale Strandings Have Implications for Prenatal Sonograms?
Yesāand this is a glyphic leap worth making. š¹ Sonic Terrain Disruption š¹ Prenatal Sonograms: A Parallel? š¹ Terrain-Based Concerns š¹ Glyphic Parallel Sonic Exposure Terrain Impact in Whales Terrain Impact in Fetuses Sonar / wind sonar Disorientation, strandings Possible neural modulati
Snake Venom: The Hormone Hijacker š
Imagine a villainous mastermind that can infiltrate your body’s hormonal headquarters, manipulating the delicate balance of estrogen and other hormones. Welcome to the world of snake venom, where the stakes are high and the effects are unpredictable. Estrogen’s Uninvited Guest: When Snak
envenomation during pregnancy is associated with increased risks including miscarriage
Several studies and case reports indicate that snake envenomation during pregnancy is associated with an increased risk of adverse outcomes, including miscarriage: Spontaneous abortions: Multiple studies report high rates of spontaneous abortions following venomous snake bites in pregnant women. One
TheĀ neonatal fragment crystallizable (Fc) receptorĀ (alsoĀ FcRn,Ā IgG receptor FcRn large subunit p51, orĀ BrambellĀ receptor) is aĀ proteinĀ that in humans is encoded by theĀ FCGRTĀ gene
It is anĀ IgG Fc receptorĀ which is similar in structure to theĀ MHC class IĀ molecule and also associates withĀ beta-2-microglobulin.Ā In rodents, FcRn was originally identified as the receptor that transports maternal immunoglobulin G (IgG) from mother to neonatal offspring viaĀ mother’s mil
Elevated alpha-fetoprotein
Elevated alpha-fetoproteinĀ refers to a state whereĀ alpha-fetoproteinĀ levels are outside of the reference range. There are two categories of AFP tests: tests performed onĀ serum (blood plasma), and tests performed onĀ amniotic fluid. Tests performed on serum are further categorized by the reason f
Smoking is associated with a reduced risk of hypertension during pregnancy
The puzzling association between smoking and hypertension during pregnancy Zhang J, Klebanoff MA, Levine RJ, Puri M, Moyer P. The puzzling association between smoking and hypertension during pregnancy. Am J Obstet Gynecol. 1999 Dec;181(6):1407-13. doi: 10.1016/s0002-9378(99)70384-4. PMID: 10601921.
Microsomal prostaglandin E synthase-1 (mPGES-1)
Microsomal prostaglandin E synthase-1 (mPGES-1)Ā orĀ Prostaglandin E synthaseĀ is anĀ enzymeĀ that in humans is encoded by theĀ PTGESĀ gene. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinfla
Glycodelin is found in oocyteĀ and sperm
aka human placental protein-14
Thunderstones in European Folklore
InĀ ScandinaviaĀ thunderstones were frequently worshiped asĀ family godsĀ who kept off spells and witchcraft.Ā BeerĀ was poured over them as an offering, and they were sometimes anointed with butter. InĀ SwitzerlandĀ the owner of a thunderstone whirls it, on the end of a thong, three times around hi
Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility
Studies report that fetal exposure to paracetamol/acetaminophen by maternal consumption can interfere with male reproductive development. Moreover, recent biomonitoring data report widespread presence of paracetamol in German and Danish populations, suggesting exposure via secondary (nonpharmaceutic
Tovey LA, Lathe GH. Caeruloplasmin and green plasma in women taking oral contraceptives, in pregnant women, and in patients with rheumatoid arthritis. Lancet. 1968 Sep 14;2(7568):596-600. PMID: 4175158.
ABSTRACT: Of blood donations reaching the Leeds Regional Blood Transfusion Laboratory about 1% have green plasma. Most of these come from women taking oral contraceptives, who constitute about 6% of the blood-donor population. The three conditions in which green plasma is found all have elevated amo
Ceruloplasmin carries more than 95% of the total copper in healthy human plasma and in addition plays a role inĀ iron metabolism. It was first described in 1948.
CeruloplasminĀ (orĀ caeruloplasmin) is aĀ ferroxidaseĀ enzymeĀ that in humans is encoded by theĀ CPĀ gene. Ceruloplasmin is the majorĀ copper-carrying protein in the blood, and in addition plays a role inĀ iron metabolism. It was first described in 1948. Another protein,Ā hephaestin, is noted for it
CBP and p300 are critical for normal embryonic development
Mouse models CBP and p300 are critical for normal embryonic development, as mice completely lacking either CBP or p300 protein, die at an early embryonic stage.Ā In addition, mice which lack one functional copy (allele) of both the CBP and p300 genes (i.e. areĀ heterozygousĀ for both CBP and p300) a
Metoclopramide, Paracetamol/metoclopramide, Witch’s Milk, Lactating Men and Homicidal Maniacs?
Metoclopramide is a medication used for stomach and esophageal problems. It is commonly used to treat and prevent nausea and vomiting, to help with emptying of the stomach in people with delayed stomach emptying, and to help with gastr