Tag: Prion
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Daniel Carleton Gajdusek (1923 – 2008) was an American physician and medical researcher who was the co-recipient (with Baruch S. Blumberg) of the Nobel Prize in Physiology or Medicine in 1976 for work on the transmissibility of kuru, implying the existence of an infectious agent, which he named an ‘unconventional virus’.
His papers are held at the National Library of Medicine in Bethesda, Maryland and at the American Philosophical Society in Philadelphia, Pennsylvania. Early life and education Gajdusek’s father, Karol Gajdusek, was a Slovak butcher from Smrdáky, Kingdom of Hungary, now Slovakia. His mother Ottilia DobrĂłczki, and maternal grandparents, ethnic Hungarians of the Calvinist faith, emigrated from Debrecen, Hungary. Gajdusek was born in Yonkers, New York, and graduated…
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Microfold cells (or M cells)
Microfold cells (or M cells) are found in the gut-associated lymphoid tissue (GALT) of the Peyer’s patches in the small intestine, and in the mucosa-associated lymphoid tissue (MALT) of other parts of the gastrointestinal tract. These cells are known to initiate mucosal immunity responses on the apical membrane of the M cells and allow for transport of microbes and particles across the epithelial cell layer from the gut lumen to the lamina…
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Peyer’s patches (aggregated lymphoid nodules)
Peyer’s patches (or aggregated lymphoid nodules) are organized lymphoid follicles, named after the 17th-century Swiss anatomist Johann Conrad Peyer. They are an important part of gut associated lymphoid tissue usually found in humans in the lowest portion of the small intestine, mainly in the distal jejunum and the ileum, but also could be detected in the duodenum. History Peyer’s patches had been observed and described by several anatomists…
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NLR family pyrin domain containing 3Â (NLRP3) (previously known as NACHT, LRR and PYD domains-containing protein 3 [NALP3] and cryopyrin)
Reference for subtitle: Finamor IA, Bressan CA, Torres-Cuevas I, Rius-PĂ©rez S, da Veiga M, Rocha MI, Pavanato MA, PĂ©rez S. Long-Term Aspartame Administration Leads to Fibrosis, Inflammasome Activation, and Gluconeogenesis Impairment in the Liver of Mice. Biology. 2021; 10(2):82. https://doi.org/10.3390/biology10020082 NLR family pyrin domain containing 3Â (NLRP3) (previously known as NACHT, LRR and PYD domains-containing protein…
