Tag: Prostaglandin
-
đ Thiocyanate and Sodium as Endogenous Antithrombotics: Reframing the Prostaglandin Paradigm
Abstract Trauma-induced clot formation is traditionally addressed through pharmacologic intervention targeting thrombotic and inflammatory pathways. However, recent frameworks suggest an overlooked endogenous axis: the thiocyanateâsodium lattice. This paper explores the role of SCNâ» and sodium in preventing vascular leakage and clot formation, especially in high-inflammation states initiated by prostaglandin cascades. 1. Introduction Injury initiates a…
-
Vascular Coherence supported by SodiumâSCNâ» lattice
The prostaglandin cascade, sparked by trauma and mediated by arachidonic acid and cyclooxygenase (COX), is a biochemical ignition sequence that destabilizes vascular coherence â precisely the kind of systemic unraveling our sodiumâSCNâ» lattice seeks to prevent. Letâs thread it together: đ„ Trauma â Arachidonic Acid â Prostaglandins â Vascular Leak The Canonical Pathway Result: Leaky…
-
Autacoids Unleashed: The Self-Made, Self-Destructive Hormones You Didnât Know You Needed
What Are Autacoids? Autacoids (or autocoids) are the bodyâs DIY hormonesâlocally produced, short-lived biochemical messengers that scream, âI got this!â before promptly fading into oblivion. The term comes from the Greek autos (self) and acos (relief or drug), which is ironic because theyâre basically the overachieving interns of the body: they do all the work locally, get no credit,…
-
Three mechanisms predominate for beneficial effects of smoking: the ‘anti-estrogenic effect’ of smoking; alterations in prostaglandin production; and stimulation of nicotinic cholinergic receptors in the central nervous system
Beneficial effects of nicotine and cigarette smoking: the real, the possible and the spurious Baron JA. Beneficial effects of nicotine and cigarette smoking: the real, the possible and the spurious. Br Med Bull. 1996 Jan;52(1):58-73. doi: 10.1093/oxfordjournals.bmb.a011533. PMID: 8746297.
-
Prenatal exposure to paracetamol/acetaminophen and precursor aniline impairs masculinisation of male brain and behaviour
Paracetamol/acetaminophen (N-Acetyl-p-Aminophenol; APAP) is the preferred analgesic for pain relief and fever during pregnancy. It has therefore caused concern that several studies have reported that prenatal exposure to APAP results in developmental alterations in both the reproductive tract and the brain. Genitals and nervous system of male mammals are actively masculinised during foetal development and…
-
AM404, aka N-arachidonoylphenolamine, is an active metabolite of paracetamolÂ
AM404, also known as N-arachidonoylphenolamine, is an active metabolite of paracetamol (acetaminophen), responsible for all or part of its analgesic action and anticonvulsant effects. Chemically, it is the amide formed from 4-aminophenol and arachidonic acid. Pharmacology It is established that AM404 increases concentrations of the endogenous cannabinoid anandamide within the synaptic cleft, contributing to its analgesic activity. This has been well characterised as involving endocannabinoid transporter inhibition, but the precise transporter responsible is yet to be…
Recent Posts
- đ§Ź Disease Table with Low Sodium Connection
- đ§ Sodium Reduction and Sodium Replacement: A History of Reformulation and Exploding Diseases, Including Many Diseases Unheard of Before Deadly Sodium Policies
- đ§ The DEADLY 1500 mg Sodium Recommendation predates the WHOâs formal global sodium reduction push by nearly a decade (and it’s even worse than that)
- đ§Ź What Is Beta-Glucuronidase?
- When Sugar Was Salt: Crystalline Confusion and the Covenant of Sweetness
Tags
ADAM ASPARTAME Birds Blood Bones Brain Bugs Cancer Columba Cows crystallography Death Death cults Eggs Etymology Gastrin Gold Growth hormone History Hormones Insulin Liver Mere Perplexity Metal Monkey Business Mythology Paracetamol Plants Poison Pregnancy Protein Religion Reproduction Rocks Salt Slavery Snakes Sodium the birds and the bees Thiocyanate Tobacco Tylenol Underworld Venom zinc