Tag: PROTEINS
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Vitellin is essential in the fertilization process, and embryonic development in egg-laying organisms
Vitellin is a protein found in the egg yolk. It is a phosphoprotein. Vitellin is a generic name for major of many yolk proteins. Vitellin has been known since the 1900s. The periodic acid-Schiff method and Sudan black B dye was used to help determine that Vitellin is a glycolipoprotein because it stained positive when tested. This protein was…
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Protein phosphorylation was first reported in 1906
Protein phosphorylation is a reversible post-translational modification of proteins in which an amino acid residue is phosphorylated by a protein kinase by the addition of a covalently bound phosphate group. Phosphorylation alters the structural conformation of a protein, causing it to become activated, deactivated, or otherwise modifying its function. Approximately 13,000 human proteins have sites that are phosphorylated. The reverse reaction of phosphorylation is called dephosphorylation, and is catalyzed by…
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Phosphorylation
In biochemistry, phosphorylation is the attachment of a phosphate group to a molecule or an ion.[1] This process and its inverse, dephosphorylation, are common in biology.[2] Protein phosphorylation often activates (or deactivates) many enzymes.[3][4] During respiration and photosynthesis Phosphorylation is essential to the processes of both anaerobic and aerobic respiration, which involve the production of adenosine triphosphate (ATP), the “high-energy” exchange medium in the cell. During aerobic respiration, ATP is synthesized…
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The transforming growth factor beta receptors
a family of serine/threonine kinase receptors involved in TGF beta signaling pathway
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Sterol carrier proteins (aka nonspecific lipid transfer proteins)
These proteins are different from plant nonspecific lipid transfer proteins but structurally similar to small proteins of unknown function from Thermus thermophilus. This domain is involved in binding sterols. The human sterol carrier protein 2 (SCP2) is a basic protein that is believed to participate in the intracellular transport of cholesterol and various other lipids. Human…
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Opioid growth factor receptor
Opioid growth factor receptor, also known as OGFr or the ζ-opioid receptor, is a protein which in humans is encoded by the OGFR gene. The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. The endogenous ligand is thus a known opioid peptide, and OGFr was originally discovered and named as a new opioid receptor zeta (ζ). However it was…
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What is Immunoprecipitation (IP)?
Immunoprecipitation (IP) is a technique used to enrich protein antigens from a complex mixture using specific antibodies. To carry out an IP, antibodies must be coupled to a solid substrate, such as agarose resin or magnetic beads, to allow for purification of the target antigens. Immunoprecipitation (IP) is the technique of precipitating a protein antigen out of solution using an antibody that…
