Tag: Proteolysis

  • ADAM25: The Testicular Troublemaker

    ADAM25 is the protein that’s making waves in the world of male reproduction! ADAM25, also known as testase 2, is like that friend who only shows up for guy’s night out. This protein is exclusively expressed in the testes, suggesting it’s got some serious business to attend to in the male reproductive system1. Picture ADAM25…

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  • Ectodomain Shedding & Sheddases & a whole bunch of Adams

    An ectodomain is the domain of a membrane protein that extends into the extracellular space (the space outside a cell). Ectodomains are usually the parts of proteins that initiate contact with surfaces, which leads to signal transduction. A notable example of an ectodomain is the S protein, commonly known as the spike protein, of the viral particle responsible for the COVID-19 pandemic. The ectodomain region of the…

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